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Peter23: Tardive dysphoria after going off sertraline


Peter23

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Could I ask one of the monitors if my zopiclone taper using the liquid formulation is reasonable. I will be reducing the zopiclone 7.5mg/5ml solution by 1ml or 1.5mg every two weeks. I am being closely supported by my primary physician every two weeks. This represents a fast taper of 20% every two weeks which was previously agreed by one of the monitors.

2000-Venlafaxine 150 mg and Olanzapine 10 mg started

2012- Venlafaxine(tapered off) to Sertraline 150 mg until 2021, added mirtazapine 30 mg until 2019

2018-2023, Oct- Pregabalin, started 150 mg to 600 mg

2019- Diazepam started 6mg

2022- July-restart mirtazapine(unsuccessful) Oct- ECT X 12, Zopliclone 7.5 mg start- present

2023- January, olanzapine decreased to 7.5 mg, Lorazepam 1 mg X 2 weeks, Diazepam increased- 20 mg, some tapering to June-Diazepam 10 mg

March- Agomelatine added-25 mg

October 9th, 2023 present meds bolded

 

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7 hours ago, Peter23 said:

This represents a fast taper of 20% every two weeks which was previously agreed by one of the monitors.

Hi @Peter23, yes this might work if you're still taking diazepam. If you're not, the recommendation would be to split the dose and taper the usual 10% per month of current dose.

 

What happened with agomelatine? I had thought you were going to reduce that first?

 

See below:

 

 

2003-2009 on and off various SSRI's for short periods

2010-2011 Ativan

2013-2021 ativan 1-1.5mg 10-12x/month, daily starting Oct 21 to help with buspar WD

2016 - Effexor 75mg, short-term

2021 Mar -Jun Buspar ADR at high dose, tapered 3 months

Oct 22/21 - Direct switch ativan to clonazepam (don't do this)

Tapered clonaz Oct/21 - Apr/23  - 0mg!

 

"Believe that your tragedies, your losses, your sorrows, your hurt, happened for you, not to you. And I bless the thing that broke you down and cracked you open, because the world needs you open" - Rebecca Campbell

 

*** Disclaimer: Please note, my suggestions/comments are based on my own personal experiences. Please consult a knowledgeable practitioner to discuss decisions regarding your medical care *** 

 

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Thanks LotusRising for your reply. I am still on diazepam 10mg daily. Do you think I would benefit by taking some of my diazepam at night once I commence my Zopiclone taper? As I am being monitored by my primary physician during my taper  I might have to extend the period of withdrawal by a week or so if I encounter severe withdrawal symptoms. 

I did start reducing the Agomelatine some time ago by shaving off 10% of the dose by weight. However I found this method unsatisfactory and abandoned it. I think it might be better to leave the Agomelatine taper at the moment and concentrate on coming of the Zopiclone first. Altostrata suggested that I come off the drugs that were acting as " brakes" like the Zopiclone and Pregabalin. I will provide updates once  I commence the Zopiclone taper. Thanks again for your reply and for the link to Z drug tapering .

2000-Venlafaxine 150 mg and Olanzapine 10 mg started

2012- Venlafaxine(tapered off) to Sertraline 150 mg until 2021, added mirtazapine 30 mg until 2019

2018-2023, Oct- Pregabalin, started 150 mg to 600 mg

2019- Diazepam started 6mg

2022- July-restart mirtazapine(unsuccessful) Oct- ECT X 12, Zopliclone 7.5 mg start- present

2023- January, olanzapine decreased to 7.5 mg, Lorazepam 1 mg X 2 weeks, Diazepam increased- 20 mg, some tapering to June-Diazepam 10 mg

March- Agomelatine added-25 mg

October 9th, 2023 present meds bolded

 

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Started the Zopiclone liquid 7.5mg/5ml on the 17/08/24. The doctor wants me to take 5ml for 2 weeks after which I will be reducing my dose by 1ml every 2 weeks. I'm currently only sleeping for 4 or 5 hours. Think this may be caused by rebound insomnia due to taking the Zopiclone for an extended period of time. 

2000-Venlafaxine 150 mg and Olanzapine 10 mg started

2012- Venlafaxine(tapered off) to Sertraline 150 mg until 2021, added mirtazapine 30 mg until 2019

2018-2023, Oct- Pregabalin, started 150 mg to 600 mg

2019- Diazepam started 6mg

2022- July-restart mirtazapine(unsuccessful) Oct- ECT X 12, Zopliclone 7.5 mg start- present

2023- January, olanzapine decreased to 7.5 mg, Lorazepam 1 mg X 2 weeks, Diazepam increased- 20 mg, some tapering to June-Diazepam 10 mg

March- Agomelatine added-25 mg

October 9th, 2023 present meds bolded

 

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