Flo75: suffering from Brintellix SD - should i reinstate?

[Flo75]

Hi, sorry in advance, I am a non-native English speaker.

 

In Sep. 2021 I was “diagnosed” with burnout syndrome, after working way too much over years, basically day and night as a vet surgeon. I was resting and things were slightly improving until dec. 21, I felt really fatigued and weak, but never low mood or depressed. Sleep was always good. In Jan. 22, I was prescribed first time in my life with an AD, Brintellix 5 mg (med history in my signature). In March 22 I was stopped from 10 mg Brintellix because of many physical symptoms and ended in hospital with weakness, muscle pains, couldn’t barely walk. What I didn’t know then, I was probably suffering from wd symptoms.

 

1. April I was set back on 5 mg, raised to 20 mg till 17. May. Suffered from severe physical smyptoms couldn’t barely walk, ataxia, muscle weakness, nausea, dizziness, vertigo & fatigue. Then the doc made me reduce again in Jul. to 10 mg, the symptoms were stabilizing after two weeks, but the doc gave me Wellbutrin 150 mg, stopped after 3 days, this was hell!! Read afterwards Wellbutrin is “doubling” the dose from Brintellix! 24. Aug I reduced to 5 mg, symptoms were stabilizing after 10 days but doc made me stop in a few days with 5 – 0 mg. Since 14. Sep. no meds at all, after 2 days all hell broke loose: itch on the whole body (never had before), flu like symptoms (never had before), neuropathic pains, muscle pains, stomach ache (never had before), weakness, headaches, light sensitivity, dizziness, fatigue and so on.

 

And yesterday I stumbled on this forum. I am speechless, angry, and sad, this is crazy, nobody ever told me to taper off slowly, this is insane. And it says in the booklet from Brintellix you can stop immediately! I’ve spent hours reading in your topics and your work is very much appreciated, wow!

 

So now I think I am suffering from wd symptoms. Should I go back now on a low dose brintellix to stabilize? And then taper off slowly? How much should I take? 0.5 mg or more? I am so desperate.

 

Right now, I am taking Vit. C 500 mg and Omega 3 fish oil since yesterday, and that’s it.

 

Thanks for your advice in advance

 

Much love

Flo75

 

 

Edited October 12, 2022 by ChessieCat
added spacing

[getofflex]

Hello, and welcome to SA.  We are a volunteer-run community of people who have been or are getting off of psychiatric drugs.  I'm glad you found us. 

 

On 10/8/2022 at 4:11 AM, Flo75 said:

I am speechless, angry, and sad, this is crazy, nobody ever told me to taper off slowly, this is insane. And it says in the booklet from Brintellix you can stop immediately!

The vast majority of us here on the forum feel equally betrayed by the mental "health care" system.  We understand what you are talking about.  I'm sorry that you have been put in this position.  

 

Can you please clarify your drug history by putting your Wellbutrin information on a separate line?  Thank you.  I'm willing to bet that the 3 days of Wellbutrin further confused your nervous system, and contributed to your symptoms.  

 

How to List Drug History in Signature

 

Here is some important information about how these drugs actually work.  This explains why we get symptoms from going off of these medications, and why it's so important to taper slowly and carefully, and be very cautious about changing our doses: 

 

How Psychiatric Drugs Remodel Your Brain

 

 

This helps you understand what withdrawal syndrome is: 

 

Video on Recovery from Psych Drugs

 

Windows and Waves Pattern of Stabilization

 

Here is a link with checklists of common WD symptoms: 

 

Dr Joseph Glenmullen Withdrawal Symptom Checklists

 

 

Here are some techniques to cope with symptoms: 

 

Non Drug Ways to Cope with Withdrawal Symptoms

 

Stability is really important when we are tapering off psych meds.  Please read the link about stability:

 

Keep It Simple, Slow, and Stable

 

 

We don't suggest many supplements, but 2 that many of us find helpful are magnesium and omega-3 fish oil. Here are the links for info about those. It is suggested to add one at a time, and start with a low dose to see how it affects you. 

Magnesium

Omega 3 Fish Oil

 

You may benefit from a small reinstatement.  Since you had a significant adverse reaction to Brintellix, I suggest you try a tiny test dose to see how it affects you.   Reinstatement is best done very carefully.  This is temporary, and after stabilizing you would then taper gradually off of this.  There is some risk involved.  Here is some information about reinstatement.  

 

About Reinstating and Stabilizing to Reduce Withdrawal Symptoms

 

If it were me, I would try a tiny test dose of 0.5 mg of Brintellix.  Give it at least a week, unless you feel significantly worse, in which case you should stop it immediately.  If in a week you don't feel a difference, or feel slightly better, we can increase the dose by a very small amount more.  Let's take it a step at a time.  Please be very careful to take your dose at the same time each and every day, at the same time of day.  What you need now is stability and consistency.  The easiest way to take this is to make your tablets into a liquid, or get a commercial liquid.  This link will explain how: 

 

Dosing and Tapering Brintellix/Trintellix

 

It is your choice as to whether or not you want to try the reinstatement.  Please let us know how this goes.  

 

 

 

Edited October 11, 2022 by getofflex

[manymoretodays]

Hi there Flo75 and welcome,

Sorry to hear of your troubles.  Oh my.  It's been rough for you, winding up in the hospital for some pretty severe physical symptoms of WD(withdrawal).  It does sound like you have read quite a bit here already.    I think it may be a combination of adverse effects from the Brintellix and WD.

Hoping we can help.  Hang in there.  You've come to the right place.

On 10/8/2022 at 3:11 AM, Flo75 said:

So now I think I am suffering from wd symptoms. Should I go back now on a low dose brintellix to stabilize? And then taper off slowly? How much should I take? 0.5 mg or more? I am so desperate.

 

Right now, I am taking Vit. C 500 mg and Omega 3 fish oil since yesterday, and that’s it.

 

Thanks for your advice in advance

 

 

Did you begin to suffer the horrible symptoms when you went back on Brintellix at 5 mg?  Or only when your dose was increased to ? 10 mg or 20 mg?

 

Thank you for putting together your signature so nicely for us.

 

And yes, you might be in a good time frame to try a small 0.5 mg reinstatement of Brintellix.  Unfortunately your symptoms have been longer lasting, but perhaps it might help a little bit.  Reinstatement works best if done right when WD symptoms appear.  And then you've had some obvious adverse reactions to the Brintellix too.  So.....  I'll give you a bit more to read over, and I think I'll confer.

 

And so, getofflex and I conferred, and agree.  Totally okay to go ahead and try that small reinstatement of 0.5 mg Trintellix now, with hopes that it will begin to mitigate some of your symptoms, even if just by a little bit.  Keep us updated with what you decide, and along the way.  Thank you.

 

Tips for tapering vortioxetine/Trintellix/Brintellix

this ^ will also help, if you reinstate to figure out how to get just a small dose to try

 

About reinstating and stabilizing to reduce withdrawal symptoms

 

More about WD(withdrawal) and our harm reduction method of tapering(Likely that you've already seen some of this, but it will be here for reference and for you to look at some more):

 

 

Why taper by 10% of my dosage?

 

When we take medications, the CNS (central nervous system) responds by making changes over the months and years we take the drug(s). When the medication is discontinued, the CNS has to undo all the changes it made.  The CNS likes stability. Rebuilding the neurotransmitter production and reactivating the receptor and transporter cells takes time -- during that rebuilding process symptoms occur.

 

Generally it only takes about 4 weeks for those changes to occur, when taking an AD.  Or a "physiologic dependency"

 

 

 

Some basics:

Brain Remodelling

What is withdrawal syndrome?

The windows and waves pattern of stabilization

 

Dr.Glenmullen’s withdrawal symptom list

 

 

 

When we take medications, the CNS (central nervous system) responds by making changes over the months and years we take the drug(s). When the medication is discontinued, the CNS has to undo all the changes it made.  The CNS likes stability. Rebuilding the neurotransmitter production and reactivating the receptor and transporter cells takes time -- during that rebuilding process symptoms occur. And sleep is really important during withdrawal.  Insomnia is no small deal.  Glad you had one good night so far.

 

We don't recommend a lot of supplements on SA, as many members report being sensitive to them due to our over-reactive nervous systems, but two supplements that we do recommend are magnesium and omega 3 (fish oil). Many people find these to be calming to the nervous system.   Read through these links, at least the first couple of posts in them, to see if what you have started makes sense so far.  We've got a lot of information around here.  I hope you like reading.

 

Magnesium, nature's calcium channel blocker 

Omega-3 fatty acids (fish oil) 

 

Okay.  Well I see another mod has responded too.  So welcome, welcome. Double welcome.

 

This is your introduction/journal page where you have now introduced yourself to the community, you can ask questions here regarding your tapering, or your case, give updates, communicate with us, and just keep a record of your journey.

 

Best.  Love, peace, healing, and growth,

manymoretodays(mmt)

 

 

 

Edited October 11, 2022 by manymoretodays
in bold

[Flo75]

12 hours ago, manymoretodays said:

Did you begin to suffer the horrible symptoms when you went back on Brintellix at 5 mg?  Or only when your dose was increased to ? 10 mg or 20 mg?

 

Thank you for putting together your signature so nicely for us.

 

And yes, you might be in a good time frame to try a small 0.5 mg reinstatement of Brintellix.  Unfortunately your symptoms have been longer lasting, but perhaps it might help a little bit.  Reinstatement works best if done right when WD symptoms appear.  And then you've had some obvious adverse reactions to the Brintellix too.  So.....  I'll give you a bit more to read over, and I think I'll confer.

 

And so, getofflex and I conferred, and agree.  Totally okay to go ahead and try that small reinstatement of 0.5 mg Trintellix now, with hopes that it will begin to mitigate some of your symptoms, even if just by a little bit.  Keep us updated with what you decide, and along the way.  Thank you.

 

 

Thank you so much for your warm double welcome and your advice! I am overwhelmed.

 

I was mostly suffering when they stopped my med immediately in March, when I was reinstated on 5 mg I had mostly nausea for a few days, and I was feeling quite okish. But when the doc told me to raise the dose to 10 and to 20 mg the adverse reactions were getting worser and worser, but he just ignored them. So, in summary I had the worst reactions when the dose was changed, especially on the high doses and when they took me off the medication.

 

So now, I reinstated 0.5 mg 4 days ago (couldn’t wait any longer) and I am feeling so much better, pretty much all symptoms are gone or significantly better, still a bit itchy in the eyes and face and weakness, but there is hope again. So, I will stay on 0.5 mg for at least 2 weeks and check if everything is bearable and if so, I will stay on 0.5 mg at least a few more weeks to stabilize my nervous system and then try my first slow taper. Should I try the 10 % reduction per month or 0.1 mg reduction per month?

 

Thank you so much so far

 

Much love and health

 

Flo

 

(I edited my signature as suggested)

 

Edited October 12, 2022 by ChessieCat
added spacing

[getofflex]

5 hours ago, Flo75 said:

So now, I reinstated 0.5 mg 4 days ago (couldn’t wait any longer) and I am feeling so much better, pretty much all symptoms are gone or significantly better, still a bit itchy in the eyes and face and weakness, but there is hope again. So, I will stay on 0.5 mg for at least 2 weeks and check if everything is bearable and if so, I will stay on 0.5 mg at least a few more weeks to stabilize my nervous system and then try my first slow taper.

I'm very glad to hear that the 0.5 mg reinstatement has been so helpful.  If it were me, I would really take it slow and easy.  Your nervous system has been through quite a lot in the past year.  It would probably benefit you to stay on the 0.5 mg dose for at least a month or two before starting to taper.  Wait until you are stable for at least a few weeks before doing another reduction. 

 

Stability

 

5 hours ago, Flo75 said:

Should I try the 10 % reduction per month or 0.1 mg reduction per month?

I wouldn't do the 0.1 mg reduction per month, as that is faster than we suggest.  It is especially important to taper really slowly at the lower doses, because at the very low doses, the drug has a disproportionately hight effect on our brains.  Please see this link which explains this. 

 

SERT Occupancy Studies

 

Pay attention to the chart there.  At the very low doses, the graph is almost vertical, showing how, at the lower doses, even a tiny dose change affects a larger number of receptors in your brain.  

 

Edited October 12, 2022 by getofflex

[Flo75]

Thank you very much, again! I think, that will be my tapering plan, 10 % reduction max. per month, we'll see how it goes.

Another question regarding supplements: I've read many times here you only recommend fish oil and magnesium but my Vitamin D levels are crazy low, but I am afraid of supplementing it, should I try and substitute with Vitamin D?

 

Flo75

[manymoretodays]

I'm just going to add, if it hasn't already been said.

To calculate 10% from your 0.5 mg dose, this is how:

0.5 mg X 0.90= 0.45 mg, which then represents a full 10% taper from your present dose

If you want to do less than 10%

multiply current dose by 0.95 mg to get a 5% taper dose

multiply current dose by 0.975% to get a 2.5% taper dose

 

That will be important, that you don't overshoot your tapers, and go too fast. 

I might go a full month or more on the 0.5 mg dose if it was me.

 

With the Vitamin D, it can be activating so definitely take it in the morning.  And start low, lower than any recommended doses for a trial at it, and until you see how you react.

Vit D3(cholecalciferol or calcitriol)

 

It's the sunshine vitamin.  So.....you might wait just until you're settled in with the reinstate before trying.  Meantime, if you can, get outside, and if it's sunny get a little D that way.

[Flo75]

11 minutes ago, manymoretodays said:

I'm just going to add, if it hasn't already been said.

To calculate 10% from your 0.5 mg dose, this is how:

0.5 mg X 0.90= 0.45 mg, which then represents a full 10% taper from your present dose

If you want to do less than 10%

multiply current dose by 0.95 mg to get a 5% taper dose

multiply current dose by 0.975% to get a 2.5% taper dose

 

That will be important, that you don't overshoot your tapers, and go too fast. 

I might go a full month or more on the 0.5 mg dose if it was me.

 

Thank you very much, I will stay on 0.5 mg for at least 4 - 6 weeks, my symptoms are still improving, I am so thankful I found SA.

Flo75

[Flo75]

I just wanted to give you a quick update, after 10 days of the reinstatement of 0.5 mg Brintellix some symptoms got slightly better or vanished (flu like symptoms, stomach ache, fatigue is also slightly better) but I am still suffering from itchiness and muscle pain / muscle aches, I feel like I was hit by a train, especially in the afternoon and evening, the pain is driving me nuts. I take my dose everday at 10:00 pm as before.

On 10/11/2022 at 8:46 PM, getofflex said:

If it were me, I would try a tiny test dose of 0.5 mg of Brintellix.  Give it at least a week, unless you feel significantly worse, in which case you should stop it immediately.  If in a week you don't feel a difference, or feel slightly better, we can increase the dose by a very small amount more.  Let's take it a step at a time.  Please be very careful to take your dose at the same time each and every day, at the same time of day.  What you need now is stability and consistency.  The easiest way to take this is to make your tablets into a liquid, or get a commercial liquid. 

 

 

Should I slightly raise my dose to 1.0 mg (or more) to try it out? I didn’t notice any adverse reactions so far to the reinstatement.

Thank you and much health and love

Flo

[manymoretodays]

Hi Flo75,

Well that sounds good then, that you are feeling some benefit but without adverse effects.

When do you take it?

And then in relation to your dosing the reinstatement how are the symptoms occurring?

Try doing some NOTES, to make clear on answering my above questions.

recording-drug-schedule-and-symptoms-to-track-patterns-and-progress

Notes

 

Use this format, shown in this sample note, and post one:

DATE:

 

6 a.m. Woke with anxiety
8 a.m. Took 2.5mg Lexapro
10 a.m. Stomach is upset
10:30 a.m. Ate breakfast
11:35 a.m. Got a headache, lasted one hour
12:35 p.m. Ate lunch
4 p.m. Feel a bit better
5 p.m. Took 2.5mg Lexapro
6 p.m. Ate dinner
9:20 p.m. Headache
10:00 p.m. Took 50mg Seroquel
10:20 p.m. Feeling dizzy
10:30 p.m. Fell asleep
2:30 a.m. Woke, took 3mg Ambien (NOT "took 1/2 tablet Ambien")
2:45 a.m. Fell asleep
4:30 a.m. Woke but got back to sleep

 

It is possible that you will feel okay in another 3 days or so, and I'm finding it takes about 2 weeks for Brintellix to get to steady state.......that's why I am saying it might be worth waiting just a bit more.

 

Do go over the reinstatement topic again too, as sometimes the reinstatement will help take the edge off WDsymptoms but won't quite completely get to back to total stability.

 

And......I would be more likely to have you, if you do decide to go up in dose, to just do that by 0.25 mg first, giving you a new dose of 0.75 mg each day and observing again.

 

In any case, I'm for waiting just a couple more days with observations, before any further updose.

 

Okay, hoping to see an update soon from you.

 

L, P, H, and G,

mmt

 

[Flo75]

Hi

thank you for your reply. I am really suffering, my muscle pain and weakness is getting worse every day, I can't barely walk, now its the 13th day since reinstatement.
I am using the liquid form (commercially available) and I am correctly mixing it, but the bottle is already 8 weeks open and I think it's not working anymore or less, becaus it says in the booklet only usable for 8 weeks once open. So now I am making a liquid with the pill, got me a professional lab mixer and using the 5 mg pills.

Or should I go back to my original last dose of 5 mg?????? I am soooo desperate, I cant anymore

I take my dose always at 10 pm and the muscle pains are starting every day earlier, 5 days ago it was in the next evening, then 3 days ago at 12 am and now already in the morning!

 

Flo

[manymoretodays]

Oh my Flo75,

It didn't sound so bad in your previous post.  A window perhaps.  And sometimes one event is not a pattern.  So, we do need to see some NOTES before any further suggests.

 

My concern.....is that the muscle pain and weakness might be part of an adverse response to the reinstatement, in which case, we would NOT want to proceed.  It may be, that as the Brintellix peaks that your symptoms occur and that it isn't WD, but an adverse effect........even on 0.5 mg.  Darn it.  I don't know for sure.  One day is not firm evidence.

Any other symptoms similar to the adverse effects you had on the higher doses, or when quickly coming off the Brintellix before?

 

Here's the Brintillex medication guide from the FDA.  When you scroll down near the bottom are the side effects/adverse effects.

 

NOTES help so much Flo75.  If you could post 24 hours of NOTES, what I described/ linked to above.  Time on the left.  Any drugs, supplements taken now on the right, as well as symptoms and sleep, etc. on the right.  Keep the times going on the left throughout the 24 hour period.  Then post it here.

 

No, I would not go all the way back up to 5 mg.  At most up to 0.75 mg total dose, with doing NOTES, or those objective observations for at least a couple of days and then posting them here too.

 

Okay, on mixing your own.

There's more about that in the Tips for tapering vortioxetine  topic too.

 

Meantime while changing form, even liquid to liquid but a new form of liquid it's best to stay put with your current dose.  The 0.5 mg dose

Rules of 3KI's, simple, slow, and stable

 

You could try some Epsom salt baths to relieve the aches and pain of your muscles.......it might make you feel weaker however, so just use much less than recommended on the package, and warm water.  It's a form of magnesium.

Either that or try a smidgen of magnesium orally/by mouth for general calming.  Start low and preferably after you've established your new liquid formulation, and have that set.

Meantime, heating pads might help.

Stay away from aspirin or ibuprofen for now as those are not indicated to use with Brintellix.

Our topic:  Muscle and joint stiffness, aches, pain or weakness

that may have some further non-drug, non-supplement coping

 

Okay, hang in there, today a better day all around,

L, P, H, and G,

mmt

 

 

Edited October 20, 2022 by manymoretodays

[Flo75]

Thanks for the detailed reply!

I think I did a mistake, I upped the dose to 1.0 mg two days ago, because the symptoms were getting worser every day on 0.5 mg, but I also took an antihistamine the last two days as suggested by my doc because she thinks I am suffering also from Histamine intolerance. So here are my notes from the last two days:

18.10.2022

7 a.m. Woke up after a well sleep, ate breakfast, 500 mg Vit. C
8 a.m. had to go to work fort he first time in a year, because of the insurance, went really well, loved it
1 p.m. ate lunch, 500 mg fish oil, really tired and weak
3 p.m. took a nap, really bad muscle pain, stomachache, headache, dyspnoea
5 p.m. took a bath
6 p.m. dinner, sprayed and massaged magnesium oil
10 p.m. 1 mg Brintellix, 120 mg fexofenadine, went to bed

19.10.2022

7 a.m. Woke up after a well sleep, ate breakfast, 500 mg Vit. C
8 a.m. did some cleaning and work in and around the house with a few breaks
12 p.m. ate lunch, 500 mg fish oil
1 p.m. crazy muscle pains, stomachache, weakness, dyspnoea
3 p.m. had a massage
4 p.m. felt better after massage
6 p.m. dinner
7 p.m. muscle pain, stomachache, weakness, sprayed and massaged magnesium oil
8 p.m. hat to put down one of our cats (I am vet), she was old and had cancer, felt relief for her
10 p.m. 1 mg Brintellix, 120 mg fexofenadine, went to bed

20.10.2022
7 a.m. Woke up after a well sleep, ate breakfast, 500 mg Vit. C
8 a.m. muscle pains, weakness, stomachache, dizzyness
10 a.m. went to the groceries, took Vit. D 500 UI as suggested by my doc
12 p.m. ate lunch, 500 mg fish oil
1 p.m. crazy muscle pains, stomachache, weakness, dizzyness
3 p.m. took a bath
4 p.m. creazy headaches, took 500 mg paracetamol, headaches getting better
5 p.m. buried our cat

The symptoms are like coming off or change in doses but more severe, especially the muscle pains, the somacheache is new and I was suffering dizziness until I reduced my dose from 20 to 10 in July, since then, never had dizziness until today. I also never had any dispnoea since coming down from 20 to 10 mg.
I just think the liquid brintellix does not the job for me, I always had problems with the liquid form, when the doc upped from 10 to 15 mg for example with the drops, just 10 to 11 mg was worser than 10 to 15 mg, same with coming down…. I don’t know

Thanks for everything

Flo75

[manymoretodays]

Hi Flo75,

Oh, I'm so sorry about your loss.  Losing a pet, your cat.......can be so very heartbreaking.

And.....it can and will add to the nervous system dysfunction.

 

What dose did you take of Brintillex then on the 20th and last night?

While you are still on the liquid, if it was me, I think I would back down to 0.75 mg for your dose(still a little updose from the 0.5 mg), keep doing NOTES, and then we can further evaluate again.

 

Anything that helps with the muscle pains?

On 10/20/2022 at 9:53 AM, Flo75 said:

The symptoms are like coming off or change in doses but more severe, especially the muscle pains, the somacheache is new and I was suffering dizziness until I reduced my dose from 20 to 10 in July, since then, never had dizziness until today. I also never had any dispnoea since coming down from 20 to 10 mg.
I just think the liquid brintellix does not the job for me, I always had problems with the liquid form, when the doc upped from 10 to 15 mg for example with the drops, just 10 to 11 mg was worser than 10 to 15 mg, same with coming down…. I don’t know

Thanks for everything

 

Good information.  Thank you.  Keep in mind some new distress might be from your recent loss.....and then may also level down as you get into your grief process.  Are you having dyspnea or breathing problems now?  Is this usual with losses or emotional distress at all for you........that you get really hit hard with sobbing, and feel like you can't breathe, dizzy, etc?

 

And okay, on the liquid.....I'm seeing that.  Let's try to stay put though without any formulation change for a couple days and see how you do, before attempting to get you back to any solid form of Brintellix?  Do you have any tablets left or available, or could you get some in the future?

 

Thanks Flo75.  I so wish it had all been smoother.  This is pretty normal, for what we see here though.  That first feeling of total recovery on the day after a reinstatement to some wobblies.  So hang in and on.

 

Best, L, P, H, and G,

mmt

 

More NOTES too please.  You did excellent notes.  Thanks.

Edited October 22, 2022 by manymoretodays

[Flo75]

Thanks for your reply again.

I started making my on liquid from the tablets and I can feel already a difference, the muscle pain is much more bearable, headaches are much milder and only short. I noticed since the reinstatement with the commercial liquid, a few days it was okish, then 7 days worser and worser, like this stuff isn’t working anymore, beacause the bottle was already open for more than 8 weeks.

I already know dyspnoea from reducing doses, back in July when I went down from 20 to 15 and 10 mg. It’s the same again. I don’t have much grief from the loss, it was time for her and she had the best life a cat could imagine, I am doing fine mentally, as always, since the beginning, I always “only” suffered physically.

I will stay on 0.75 mg and will make my on liquid from my tablets which I have lot left, I can buy them by myself as vet doc anyway, so no worries there.

Thanks again

Flo

20.10.2022
.
6 p.m. dinner
10 p.m. 0.75 mg Brintellix (tablet solved in liquid)

21.10.2022
7 a.m. Woke up after a well sleep, ate breakfast, 500 mg Vit. C
8 a.m. some stomach ache, some weird pain in the private parts
10 a.m. did some work in and around the house
12 p.m. had dinner, 500 mg fish oil dyspnoea, weakness
5 p.m. “evening crash” (I know this from changing doses)
6 p.m. dinner, some muscle pain, slight vertigo
10 p.m. 0.75 mg Brintellix (tablet solved in liquid)

22.10.2022
7 a.m. Woke up after a ok sleep, ate breakfast, 500 mg Vit. C
8 a.m. some weird pain in the private parts
9 a.m. went to work
1 p.m. dinner, some dyspnoea, weakness
2 p.m. took a nap
6 p.m. dinner, 500 mg fish oil, some muscle pain, some weird pain behind the sternum and back

[manymoretodays]

Hi Flo75,

Okay, that's good......you tolerate the self made better than the other, and if it expires too quickly it's likely not a good plan for the long haul......given you are just on a mini reinstatement dose.

 

Are you leveling off now, with symptoms?  I did see the notes, and proud of you.......getting on with work and things.  On the second day, you didn't experience the evening crash......that bodes well.  By leveling off, I just mean the same symptoms, that are tolerable, and that you can function with.  So......I am hoping for that for you now. 

Do update your signature.

 

And I'll watch for your update.  It will be nice if/when you can just sit tight for a little while......I'd say at least a good couple of months, before tapering again.....and then just at those 10% increments.

 

L, P, H, and G,

mmt

[Flo75]

Hi mmt

 

Thanks again for your reply, this means a lot to me.

I am now 10 days in the reinstatment I can feel improvments every day, a lot less muscle aches, still there but okish, had 2 "evening crashes" last week but still improving. Sometimes the dizziness and lightheadedness is really distubring but I can manage it. The fatigue is also slightly getting better. But the weird everyday changing symptoms are pretty much gone.

I will stay put on my dose for few months (thats scary) and keep you updated.

Thanks again

Flo