Jump to content

Recommended Posts

Posted
Hi there, 
 
I have been lurking on this site for quite a long time and too afraid to share my story, but I am reaching the point where I really need some help. 
 
To give you a bit of a case history: 
 
I am 38 now and was diagnosed with depression and anxiety at the age of 14 after suffering some pretty debilitating and terrifying panic attacks. At 14, I was put on Paxil  (20mg) and later Wellbutrin (300mg), which was added to address the sexual side effects of Paxil. The Paxil seemed like a miracle when I first began it, and for many years later, and I felt entirely in "remission" for nearly two decades. Over the years, I would occasionally attempt to lower my dosages, but would suffer from brain fog and a recurring depression. About 6 years ago, I began to feel that the medication was no longer actually working -- I was depressed and felt an increasing sense of numbness and anhedonia. I experienced no happiness at all from my life -- no sadness either, really. Just blah. My memory was also getting quite worrisome -- I'd begun to regularly forget people's names. 
 
I met with a psychiatrist who advised me to switch from Paxil to Prozac to bridge to zero meds. I cross-tapered from the Paxil to the Prozac (20mg) over a period of about three months. It was a rocky period, with lots of what I now recognize as akathisia, anxiety, agitation, and GI symptoms. But I managed to make it without any brain zaps, which had hobbled all other previous attempts of mine. I then did a very fast taper of the Prozac and Wellbutrin to zero in probably two and a half months. At first, all seemed fine enough. And then, like clockwork, three months in, I suffered a terrible depressive episode, much worse than any I'd had before the meds. I reinstated the Prozac but now at 15mg, because I found side effects at 20mg (tremors, anxiety, palpitations) undoable. At this first resinstatement, I began to have tinnitus, which has never gone away, but otherwise seemed to do okay, if not great. 
 
This sense of not really doing great caused my psychiatrist to try to switch me from Prozac to Cymbalta. After a month on the latter, severely depressed, I went back to the Prozac, and then switched to Trintellix. The Trintellix was awful and left me in a terrible depression, although I now wonder if this was also due to withdrawal symptoms from the Prozac. Over this time, I began to experience debilitating brain fog along with the mood swings and intense anhedonia. 
 
Last September, 2021, I finally went back to the Prozac after three months off. The reinstatement took away the worst of the depression, but the brain fog never abated and I began to suffer from terrible fatigue as well, along with recurring episodes of derealization and depersonalization. I tried ketamine infusions, which I found did nothing but make me feel even more derealized. 
 
Over the last year, I changed my diet entirely, adopting a whole-foods, gluten-, dairy-, alcohol-free diet. I began to think my symptoms (the brain fog, attentional difficulties, fatigue) were due to an organic physiological issue and did a battery of tests with a battery of physicians, none of which revealed anything wrong. 
 
Finally, over the last several months, I found this website and began to suspect that my symptoms were not being alleviated by the medications but exacerbated by them. In July, I began a very slow taper of the Prozac. It has been quite difficult even with very small cuts. 
 
Essentially, I am now in a place where I am wondering two things: 
 
1) Because of the timeline of my symptoms, is it possible that what I have been experiencing is actually an adverse reaction to the reinstatement of the Prozac? I never had any fatigue before the back-and-forth of drugs and then landing back on Prozac, for instance. If so, does that mean I should be accelerating my taper? 
 
2) The advice on this site is to cut and then hold until the nervous system stabilizes, but it feels to me like my nervous system never quite really stabilizes. Do I keep going anyway? 
 
Thank you to anyone for your help. This is such a difficult, lonely process, and I am very grateful that this group even exists. 
 
 


 

1997-2019: Paxil (20mg), eventually pooped out; 2000-present: Wellbutrin (300mg); 

Sept - Nov, 2019: Bridged from Paxil to Prozac (20mg). Many withdrawal symptoms but manageable. 

Nov, 2019 - Jan, 2020: Fast taper of Prozac and Wellbutrin. Few symptoms. 

Mar, 2020Terrible depression. Reinstated both Prozac (at 15mg) and Wellbutrin. 

Nov, 2020: Prozac seemingly not effective (still depressed, brain fog), switched to Cymbalta. 

Dec, 2020: Cymbalta not effective, reinstated Prozac. Major symptoms began around here: depression, anxiety, brain fog.

Jan, 2021: Switched from Prozac to Trintellix. Symptoms greatly worsened. 

Mar, 2021: Reinstated Prozac. Symptoms abated somewhat but never entirely. Fatigue grew worse from this point on. 

Aug, 2021: Ketamine infusions. Little if any effect. 

Jul - Oct 2022: Began slow taper of Prozac from 15mg. Currently at 12mg. 

 

 

Posted (edited)
Prozac Taper Intro
 
Hi there, 
 
I have been lurking on this site for quite a long time and too afraid to share my story, but I am reaching the point where I really need some help. 
 
To give you a bit of a case history: 
 
I am 38 now and was diagnosed with depression and anxiety at the age of 14 after suffering some pretty debilitating and terrifying panic attacks. At 14, I was put on Paxil  (20mg) and later Wellbutrin (300mg), which was added to address the sexual side effects of Paxil. The Paxil seemed like a miracle when I first began it, and for many years later, and I felt entirely in "remission" for nearly two decades. Over the years, I would occasionally attempt to lower my dosages, but would suffer from brain fog and a recurring depression. About 6 years ago, I began to feel that the medication was no longer actually working -- I was depressed and felt an increasing sense of numbness and anhedonia. I experienced no happiness at all from my life -- no sadness either, really. Just blah. My memory was also getting quite worrisome -- I'd begun to regularly forget people's names. 
 
I met with a psychiatrist who advised me to switch from Paxil to Prozac to bridge to zero meds. I cross-tapered from the Paxil to the Prozac (20mg) over a period of about three months. It was a rocky period, with lots of what I now recognize as akathisia, anxiety, agitation, and GI symptoms. But I managed to make it without any brain zaps, which had hobbled all other previous attempts of mine. I then did a very fast taper of the Prozac and Wellbutrin to zero in probably two and a half months. At first, all seemed fine enough. And then, like clockwork, three months in, I suffered a terrible depressive episode, much worse than any I'd had before the meds. I reinstated the Prozac but now at 15mg, because I found side effects at 20mg (tremors, anxiety, palpitations) undoable. At this first resinstatement, I began to have tinnitus, which has never gone away, but otherwise seemed to do okay, if not great. 
 
This sense of not really doing great caused my psychiatrist to try to switch me from Prozac to Cymbalta. After a month on the latter, severely depressed, I went back to the Prozac, and then switched to Trintellix. The Trintellix was awful and left me in a terrible depression, although I now wonder if this was also due to withdrawal symptoms from the Prozac. Over this time, I began to experience debilitating brain fog along with the mood swings and intense anhedonia. 
 
Last September, 2021, I finally went back to the Prozac after three months off. The reinstatement took away the worst of the depression, but the brain fog never abated and I began to suffer from terrible fatigue as well, along with recurring episodes of derealization and depersonalization. I tried ketamine infusions, which I found did nothing but make me feel even more derealized. 
 
Over the last year, I changed my diet entirely, adopting a whole-foods, gluten-, dairy-, alcohol-free diet. I began to think my symptoms (the brain fog, attentional difficulties, fatigue) were due to an organic physiological issue and did a battery of tests with a battery of physicians, none of which revealed anything wrong. 
 
Finally, over the last several months, I found this website and began to suspect that my symptoms were not being alleviated by the medications but exacerbated by them. In July, I began a very slow taper of the Prozac, with plans to go off that before touching the Wellbutrin. It has been quite difficult even with very small cuts. 
 
Essentially, I am now in a place where I am wondering two things: 
 
1) Because of the timeline of my symptoms, is it possible that what I have been experiencing is actually an adverse reaction to the reinstatement of the Prozac? I never had any fatigue before the back-and-forth of drugs and then landing back on Prozac, for instance. If so, does that mean I should be accelerating my taper? 
 
2) The advice on this site is to cut and then hold until the nervous system stabilizes, but it feels to me like my nervous system never quite really stabilizes. Do I keep going anyway? 
 
Thank you to anyone for your help. This is such a difficult, lonely process, and I am very grateful that this group even exists. 

 

 

Edited by ChessieCat
added Intro topic title before merging with intro topic

1997-2019: Paxil (20mg), eventually pooped out; 2000-present: Wellbutrin (300mg); 

Sept - Nov, 2019: Bridged from Paxil to Prozac (20mg). Many withdrawal symptoms but manageable. 

Nov, 2019 - Jan, 2020: Fast taper of Prozac and Wellbutrin. Few symptoms. 

Mar, 2020Terrible depression. Reinstated both Prozac (at 15mg) and Wellbutrin. 

Nov, 2020: Prozac seemingly not effective (still depressed, brain fog), switched to Cymbalta. 

Dec, 2020: Cymbalta not effective, reinstated Prozac. Major symptoms began around here: depression, anxiety, brain fog.

Jan, 2021: Switched from Prozac to Trintellix. Symptoms greatly worsened. 

Mar, 2021: Reinstated Prozac. Symptoms abated somewhat but never entirely. Fatigue grew worse from this point on. 

Aug, 2021: Ketamine infusions. Little if any effect. 

Jul - Oct 2022: Began slow taper of Prozac from 15mg. Currently at 12mg. 

 

 

  • ChessieCat changed the title to Boone: tapering Prozac
  • Moderator Emeritus
Posted (edited)

Hi there Boone, and welcome,

Oh man, I'm sorry as it doesn't sounds like the prozac bridge really helped,  nor did the CT's, and then all the subsequent efforts to treat WD(withdrawal) further just confused and messed up your nervous system.  There is definitely hope though and healing.

You might as well add the ketamine to your signature.  Just so we see it.  That was September 2021 I think.  And thank you for getting that done.

 

Okay, so you are looking to get stabilized a bit further, prior to tapering again, it sounds like.  I think that would be a good idea. 

 

Your symptoms are fairly common ones that we do see here.  Likely some WD(withdrawal) and some of that is nervous system destabilization too.  It does occur after multiple drug trials.  Your symptoms sound pretty frustrating right now, in changing and then in intensity and persistence.  This could be an adverse effect in the way of a drug or drug interactions too.

 

Good stuff here:  Before you begin tapering-what you need to know(just click on the underlined passage to go to the topic, and then do scroll up to the first post in topic, and start there if need be)

And this will be helpful to you too, I think:  Are We There Yet? How Long is Withdrawal Going to Take?

 

How have you been tapering the Prozac?

 

When do you take your Wellbutrin?

When do you take your Prozac?

 

Please do a drug interaction check Drugs.com and then please link us to the results, or copy and paste here.  Let us know what you think.

 

And I'm going to give you more information now too, for you to look at, and learn.  I think you are in the right place now and hope we can help.  As you've found there are no quick solutions and time and patience are required.  Which you do have.

 

We go with a harm reduction approach to tapering.  With tapering by 10% or less of each previous dose.

*Why taper by 10% of my dosage

 

Here is how we like to manage tapers when multiple drugs are involved:

*Taking multiple psych drugs? Which drug to taper first?

Although you are on presently two AD's(antidepressants) I think it is likely that the Wellbutrin is more accelerating.  What do you think?

 

*Tips for tapering Prozac(fluoxetine)

 

*Tips for tapering Wellbutrin SR, XR, XL/Zyban(buproprion)

 

More about what happens when we come off our drugs/medications, and WD:
Brain Remodelling
 
 

 

When we take medications, the CNS (central nervous system) responds by making changes over the months and years we take the drug(s). When the medication is discontinued, the CNS has to undo all the changes it made.  The CNS likes stability. Rebuilding the neurotransmitter production and reactivating the receptor and transporter cells takes time -- during that rebuilding process symptoms occur. And sleep is really important during withdrawal. 
 
We don't recommend a lot of supplements on SA, as many members report being sensitive to them due to our over-reactive nervous systems, but two supplements that we do recommend are magnesium and omega 3 (fish oil). Many people find these to be calming to the nervous system.  

 

Omega-3 fatty acids (fish oil) 

 

I haven't gone into symptoms that you have reported yet, and how you might begin to cope with them, and manage.  We can do that in the future.  Many of us rely on non-drug coping, and do learn to develop new practices which help greatly to get by.  And so, know you are not alone in this journey of yours.  Many here can relate.

 

I will just link to the:

Symptoms and Self Care Forum.

and you'll see it from the Home Page too. 

There you can:

-Read about what others have done for a symptom you may have
- Ask about symptoms, share questions and information
- Find information about supplements and other treatments

 

There is a search feature at the top right of each forum page, you can utilize as well.

 

This is your introduction/journal page where you have now introduced yourself to the community, you can ask questions here regarding your case and tapering, give updates, and just keep a record of your journey.  Just one Introduction per member please.  Thank you.

Welcome aboard!

 

Best. Love, peace, healing, and growth,

manymoretodays(mmt)

 

Edited by manymoretodays
clarity,grammar

Late 2023- gone to emeritus status, inactive, don't @ me, I can check who I've posted on, and I'm not really here like I used to be......thanks.

Started with psycho meds/psychiatric care circa 1988.  In retrospect, and on contemplation, situational overwhelm.

Rounding up to 30 years of medications(30 medication trials, poly-pharmacy maximum was 3 at one time).

5/28/2015-off Adderal salts 2.5mg. (I had been on that since hospital 10/2014)

12/2015---just holding, holding, holding, with trileptal/oxcarb at 75 mg. 1/2 tab at hs.  My last psycho med ever!  Tapered @ 10% every 4 weeks, sometimes 2 weeks to

2016 Dec 16 medication free!!

Longer signature post here, with current supplements.

Herb and alcohol free since 5/15/2016.  And.....I quit smoking 11/2021. Lapsed.  Redo of quit smoking 9/28/2022, and again finally 5/25/24.  Can you say Hallelujah?(took me long enough)💜

None of my posts are intended as medical advice.  Please discuss any decisions about your medical care with a knowledgeable medical provider.  My success story:  Blue skies ahead, clear sailing

 

Posted

Thank you so much for the thoughtful and compassionate response. I really appreciate it. 

 

So it sounds like the recommendation would be to continue holding at 12mg of Prozac until I achieve greater stabilization? I have been holding for the past several weeks anyway, after getting COVID at the beginning of the month, which seems to have exacerbated everything -- fatigue, brain fog, lightheadedness, derealization. It's been three and a half weeks since I tested positive, so I'm hopeful these symptoms will begin to subside soon, but obviously incredibly anxious about them, and feeling terrified of long COVID. 

 

If/when I return to something like a baseline, my hesitation in holding much longer is that I held at 15mg of Prozac for over a year and my symptoms waxed and waned but never truly went away. Should I be waiting for them to go away entirely before continuing? The fact that the symptoms never really went away is what made me wonder if what I was experiencing were ongoing adverse effects from the Prozac, rather than WD... 

 

To answer your questions: 

 

How have you been tapering the Prozac? I switched to the liquid, which has made it very easy.

 

When do you take your Wellbutrin? Every morning, once a day. 

When do you take your Prozac? Every morning, once a day. 

 

Please do a drug interaction check: Here is what I got back for Wellbutrin XL (I take the name brand) and fluoxetine: https://www.drugs.com/interactions-check.php?drug_list=440-2469,1115-0 

 

Wellbutrin, I know, increases the levels of fluoxetine, so I figured it was best to taper the fluoxetine first, since going down on the Wellbutrin could create the sensation of going down on both. 

 

Thank you again for the response and the links. 

 

1997-2019: Paxil (20mg), eventually pooped out; 2000-present: Wellbutrin (300mg); 

Sept - Nov, 2019: Bridged from Paxil to Prozac (20mg). Many withdrawal symptoms but manageable. 

Nov, 2019 - Jan, 2020: Fast taper of Prozac and Wellbutrin. Few symptoms. 

Mar, 2020Terrible depression. Reinstated both Prozac (at 15mg) and Wellbutrin. 

Nov, 2020: Prozac seemingly not effective (still depressed, brain fog), switched to Cymbalta. 

Dec, 2020: Cymbalta not effective, reinstated Prozac. Major symptoms began around here: depression, anxiety, brain fog.

Jan, 2021: Switched from Prozac to Trintellix. Symptoms greatly worsened. 

Mar, 2021: Reinstated Prozac. Symptoms abated somewhat but never entirely. Fatigue grew worse from this point on. 

Aug, 2021: Ketamine infusions. Little if any effect. 

Jul - Oct 2022: Began slow taper of Prozac from 15mg. Currently at 12mg. 

 

 

  • Moderator Emeritus
Posted (edited)

Hi Boone!

Oooh, and Covid at the beginning of the month......yes, that throws a damper into things.  You don't want to taper right away, or while recovering from that.

Was it a tough case?  The Covid symptoms themself?  I do see you've had definitely an exacerbation of WD symptoms.

 

You will think I'm odd perhaps, and don't think that I am trivializing either........but, what you think about, can influence outcomes sometimes.  So, if at all possible....... think and imagine your complete healing from Covid. 

 

5 hours ago, Boone said:

If/when I return to something like a baseline, my hesitation in holding much longer is that I held at 15mg of Prozac for over a year and my symptoms waxed and waned but never truly went away. Should I be waiting for them to go away entirely before continuing? The fact that the symptoms never really went away is what made me wonder if what I was experiencing were ongoing adverse effects from the Prozac, rather than WD... 

 

Look at the stability section in the Are We There Yet? topic I gave you.  Your baseline stability may be different from your healthiest baseline ever, but tolerable. 

Had you been tapering by 10% of each previous dose?

And.....when did you go down to 12 mg Prozac?  The day in October?

 

Do you take your Wellbutrin and Prozac at the same time every morning?

What I might do now, or soon......before resuming tapering, is split your timing with your 2 drugs.  Move one away from the other by first an hour, and then another hour, until they are taken 2 hours apart.

And yes, you might feel a few bumps, but I just think it would be the safer route to take now, and that's what I'd do.

 

Don't taper while moving your dose, or for a few weeks after.  By then you might be ready to go again too, with tapering.  It can be really hard predicting the CYP450 interactions and then basing a taper around just that too........from what I've seen. 

 

Sending no long Covid for Boone......that's not going to happen thoughts!

5 hours ago, Boone said:

- fatigue, brain fog, lightheadedness, derealization.

 

Are these symptoms different or about the same as the symptoms you were having pre-Covid?  It sounds like you have Windows and Waves too.  That's good.  Windows are good, and a sign of healing.

 

And yes.  I'd HOLD longer than just a couple of weeks from your last taper.  4-6 weeks might be good total time.  Longer is okay too, if you want to be sure you are at a WD stable before tapering.   Your present symptoms almost sound like your WD stable symptoms so that's good too.  Not great if you are in them, I know, but you may actually be at a WD stable now.

 

L, P, H, and G,

mmt

Edited by manymoretodays

Late 2023- gone to emeritus status, inactive, don't @ me, I can check who I've posted on, and I'm not really here like I used to be......thanks.

Started with psycho meds/psychiatric care circa 1988.  In retrospect, and on contemplation, situational overwhelm.

Rounding up to 30 years of medications(30 medication trials, poly-pharmacy maximum was 3 at one time).

5/28/2015-off Adderal salts 2.5mg. (I had been on that since hospital 10/2014)

12/2015---just holding, holding, holding, with trileptal/oxcarb at 75 mg. 1/2 tab at hs.  My last psycho med ever!  Tapered @ 10% every 4 weeks, sometimes 2 weeks to

2016 Dec 16 medication free!!

Longer signature post here, with current supplements.

Herb and alcohol free since 5/15/2016.  And.....I quit smoking 11/2021. Lapsed.  Redo of quit smoking 9/28/2022, and again finally 5/25/24.  Can you say Hallelujah?(took me long enough)💜

None of my posts are intended as medical advice.  Please discuss any decisions about your medical care with a knowledgeable medical provider.  My success story:  Blue skies ahead, clear sailing

 

Posted
1 hour ago, manymoretodays said:

You will think I'm odd perhaps, and don't think that I am trivializing either........but, what you think about, can influence outcomes sometimes.  So, if at all possible....... think and imagine your complete healing from Covid. 

 

It's great advice and I appreciate it! 

 

1 hour ago, manymoretodays said:

Had you been tapering by 10% of each previous dose?

And.....when did you go down to 12 mg Prozac?  The day in October?

 

I had been tapering by even less actually -- more like 6% a month, 3% every two weeks. I wonder if it would be better, when I do get back to tapering, to just do one cut a month rather than two -- I found I had symptoms from each individual cut a few weeks after I made it, so splitting them up just seemed to double the WD. I decided to really slow it down this past month and went from 12.2 to 12 on October 4. I'm not sure the smaller cuts actually make much of a difference -- it seems I get the same level of symptoms regardless. Is that possible? 

1 hour ago, manymoretodays said:

 

Do you take your Wellbutrin and Prozac at the same time every morning?

What I might do now, or soon......before resuming tapering, is split your timing with your 2 drugs.  Move one away from the other by first an hour, and then another hour, until they are taken 2 hours apart.

This is not something I have tried... I will definitely do so when I get back to tapering! 

1 hour ago, manymoretodays said:

Are these symptoms different or about the same as the symptoms you were having pre-Covid?  It sounds like you have Windows and Waves too.  That's good.  Windows are good, and a sign of healing.

 

The symptoms are worse since having COVID, but they definitely are the same ones. 

 

And one of the reasons I did begin to have hope this summer is that, when I began tapering, I began to have real windows for the first time in years, it felt like. It felt like the lower I was going on the medication, the more myself I was feeling -- once the WD from the last cut lessened, which usually took a couple weeks. 

 

Thank you thank you for all of the wisdom and guidance! I can't tell you how much it means... 

1997-2019: Paxil (20mg), eventually pooped out; 2000-present: Wellbutrin (300mg); 

Sept - Nov, 2019: Bridged from Paxil to Prozac (20mg). Many withdrawal symptoms but manageable. 

Nov, 2019 - Jan, 2020: Fast taper of Prozac and Wellbutrin. Few symptoms. 

Mar, 2020Terrible depression. Reinstated both Prozac (at 15mg) and Wellbutrin. 

Nov, 2020: Prozac seemingly not effective (still depressed, brain fog), switched to Cymbalta. 

Dec, 2020: Cymbalta not effective, reinstated Prozac. Major symptoms began around here: depression, anxiety, brain fog.

Jan, 2021: Switched from Prozac to Trintellix. Symptoms greatly worsened. 

Mar, 2021: Reinstated Prozac. Symptoms abated somewhat but never entirely. Fatigue grew worse from this point on. 

Aug, 2021: Ketamine infusions. Little if any effect. 

Jul - Oct 2022: Began slow taper of Prozac from 15mg. Currently at 12mg. 

 

 

  • Moderator Emeritus
Posted
On 10/28/2022 at 3:50 PM, Boone said:

And one of the reasons I did begin to have hope this summer is that, when I began tapering, I began to have real windows for the first time in years, it felt like. It felt like the lower I was going on the medication, the more myself I was feeling -- once the WD from the last cut lessened, which usually took a couple weeks. 

 

Okay then.  This is good.  And that's about par or right for when you make a change in Prozac and when you might feel it. 

Still though, going down with each taper by 10% or less is going to be the best thing you can do.......as far as hopefully minimizing WD, and having a successful taper.

 

It will take about 6 months to get to half of your starting dose, doing the 10% tapers every 4 weeks.

brassmonkey talks about this here:

 

How Long? The Bottom Line.

 

The split, of getting to at least 2 hours between your Wellbutrin and Prozac is to limit, hopefully......the additive effects that they have on each other. 

On 10/28/2022 at 9:20 AM, Boone said:

Wellbutrin, I know, increases the levels of fluoxetine, so I figured it was best to taper the fluoxetine first, since going down on the Wellbutrin could create the sensation of going down on both. 

Yes, this could be......reading further down in the professional interactions check.

https://www.drugs.com/interactions-check.php?drug_list=440-203,1115-648&types[]=major&types[]=minor&types[]=moderate&types[]=food&types[]=therapeutic_duplication&professional=1

 

I was more thinking that it would possibly limit the epileptogenic factor mentioned there.  Or hopefully it would.  I mean I don't know for sure.  So that's why I wanted you to spread them out a little and then see how you feel BEFORE resuming any taper at all.

 

And good too, you are not taking chances, and are often tapering by less than 10%.

 

And so, they both seem to be more accelerating, or possibly activating?  Have you ever taken either one singularly?  And if so what was your overall impression of the effect then?  You've been on both for awhile now.

Why did you choose to start with the taper of Prozac?

I do see in your signature that when you have reinstated Prozac that fatigue came back, and possibly cog fog, depression.

 

Okay, I will confer(ask for some more staff input), as I'm not certain what else to ask you now.  And wonder myself if the taper of Prozac is best to do first.

 

Meantime, HOLD if you will, other than getting to a 2 hour spacing between the Wellbutrin and Prozac.

How's the healing from Covid going?

 

L, P, H, and G,

mmt

 

 

Late 2023- gone to emeritus status, inactive, don't @ me, I can check who I've posted on, and I'm not really here like I used to be......thanks.

Started with psycho meds/psychiatric care circa 1988.  In retrospect, and on contemplation, situational overwhelm.

Rounding up to 30 years of medications(30 medication trials, poly-pharmacy maximum was 3 at one time).

5/28/2015-off Adderal salts 2.5mg. (I had been on that since hospital 10/2014)

12/2015---just holding, holding, holding, with trileptal/oxcarb at 75 mg. 1/2 tab at hs.  My last psycho med ever!  Tapered @ 10% every 4 weeks, sometimes 2 weeks to

2016 Dec 16 medication free!!

Longer signature post here, with current supplements.

Herb and alcohol free since 5/15/2016.  And.....I quit smoking 11/2021. Lapsed.  Redo of quit smoking 9/28/2022, and again finally 5/25/24.  Can you say Hallelujah?(took me long enough)💜

None of my posts are intended as medical advice.  Please discuss any decisions about your medical care with a knowledgeable medical provider.  My success story:  Blue skies ahead, clear sailing

 

  • Moderator Emeritus
Posted

Hey Boone,

How are you today?

You know, you could keep moving the Prozac towards night time.......spacing it even further from the Wellbutrin.

You had said that the Prozac seemed to make you more fatigued I think.

 

I should have asked for you to do NOTES too. 

So will ask for those now.  They give us valuable objective information as to your symptoms before and after each of your drugs.

Recording drug schedule and symptoms to track patterns and progress

The time of day, dosage, and severity of symptoms are essential information. Include

 

- Time and dosage for all drugs taken throughout the day, psychiatric and non-psychiatric.

- Following each dose, note any symptoms. If you are having a reaction to the drug, it may take hours for a symptom to show up -- that's why we ask you to keep notes all day long.

- If you're not taking any drugs, your symptoms throughout the day.

- Your sleep pattern. Since so many drugs disturb sleep, if you find you're waking in the middle of the night, it could be from a drug you took earlier in the evening. If you're not taking any drugs, there may be ways you can improve your sleep.

And so forth. A diary, in chronological order, looking something like this:
 

Example:


DATE:

 

6 a.m. Woke with anxiety
8 a.m. Took 2.5mg Lexapro
10 a.m. Stomach is upset
10:30 a.m. Ate breakfast
11:35 a.m. Got a headache, lasted one hour
12:35 p.m. Ate lunch
4 p.m. Feel a bit better
5 p.m. Took 2.5mg Lexapro
6 p.m. Ate dinner
9:20 p.m. Headache
10:00 p.m. Took 50mg Seroquel
10:20 p.m. Feeling dizzy
10:30 p.m. Fell asleep
2:30 a.m. Woke, took 3mg Ambien (NOT "took 1/2 tablet Ambien")
2:45 a.m. Fell asleep
4:30 a.m. Woke but got back to sleep

 

Even just a couple of days worth.  Post them right here, in a reply box.  That always help to see things more clearly.

Times on the left.  Then basically everything else to the right of the times.  All Drug(s) by name and dose.  Any supplements.  Symptoms as they occur throughout the day.  Some will rate symptoms with intensities, like from 1-10.  Describe your symptoms too, that's helpful.

 

And possibly you might wish to consider alternating tapers at some point.  Wellbutrin one month and then Prozac the other.  You can of course base alternating tapers on symptoms too.

 

Okay.  Hoping that the Covid is soon just history and you are feeling better.

Update soon.

Thanks.

 

L, P, H, and G,

mmt

Late 2023- gone to emeritus status, inactive, don't @ me, I can check who I've posted on, and I'm not really here like I used to be......thanks.

Started with psycho meds/psychiatric care circa 1988.  In retrospect, and on contemplation, situational overwhelm.

Rounding up to 30 years of medications(30 medication trials, poly-pharmacy maximum was 3 at one time).

5/28/2015-off Adderal salts 2.5mg. (I had been on that since hospital 10/2014)

12/2015---just holding, holding, holding, with trileptal/oxcarb at 75 mg. 1/2 tab at hs.  My last psycho med ever!  Tapered @ 10% every 4 weeks, sometimes 2 weeks to

2016 Dec 16 medication free!!

Longer signature post here, with current supplements.

Herb and alcohol free since 5/15/2016.  And.....I quit smoking 11/2021. Lapsed.  Redo of quit smoking 9/28/2022, and again finally 5/25/24.  Can you say Hallelujah?(took me long enough)💜

None of my posts are intended as medical advice.  Please discuss any decisions about your medical care with a knowledgeable medical provider.  My success story:  Blue skies ahead, clear sailing

 

  • Moderator Emeritus
Posted (edited)

Any updates Boone?

I know the NOTES can seem to throw a lot of members so...........

On 10/28/2022 at 9:20 AM, Boone said:

So it sounds like the recommendation would be to continue holding at 12mg of Prozac until I achieve greater stabilization? I have been holding for the past several weeks anyway, after getting COVID at the beginning of the month, which seems to have exacerbated everything -- fatigue, brain fog, lightheadedness, derealization. It's been three and a half weeks since I tested positive, so I'm hopeful these symptoms will begin to subside soon, but obviously incredibly anxious about them, and feeling terrified of long COVID. 

 

If/when I return to something like a baseline, my hesitation in holding much longer is that I held at 15mg of Prozac for over a year and my symptoms waxed and waned but never truly went away. Should I be waiting for them to go away entirely before continuing? The fact that the symptoms never really went away is what made me wonder if what I was experiencing were ongoing adverse effects from the Prozac, rather than WD... 

 

Covid unfortunate at this time.  It is what it is.......... and I think you ARE most definitely on the right track with your current thinking.

To HOLD until such a time that you feel more WD stable to proceed again with a taper.

 

I am hopeful for you too, and a good recovery from the Covid.  Try not to go there......to worries around long Covid.

 

Likely you are experiencing a long haul re-balancing of sort, or getting to some new homeostasis.  Protracted Paxil WD, and then all the upsets as other drugs were tried, and now Covid to wait out too.

 

Do please give a try at the NOTES sooner, rather than later.  They are not hard once you get the hang of them.  And that won't be something you need to do forever, as far as posting them here.   Because I'm wanting to see objectively, when you shift your Wellbutrin away from the Prozac.

 

Okay.  Hope you're still popping in and are doing well enough.  It can be a longer haul than bargained for.  I'll attest to that.

 

Best, L, P, H, and G,

mmt

 

Edited by manymoretodays
grammar

Late 2023- gone to emeritus status, inactive, don't @ me, I can check who I've posted on, and I'm not really here like I used to be......thanks.

Started with psycho meds/psychiatric care circa 1988.  In retrospect, and on contemplation, situational overwhelm.

Rounding up to 30 years of medications(30 medication trials, poly-pharmacy maximum was 3 at one time).

5/28/2015-off Adderal salts 2.5mg. (I had been on that since hospital 10/2014)

12/2015---just holding, holding, holding, with trileptal/oxcarb at 75 mg. 1/2 tab at hs.  My last psycho med ever!  Tapered @ 10% every 4 weeks, sometimes 2 weeks to

2016 Dec 16 medication free!!

Longer signature post here, with current supplements.

Herb and alcohol free since 5/15/2016.  And.....I quit smoking 11/2021. Lapsed.  Redo of quit smoking 9/28/2022, and again finally 5/25/24.  Can you say Hallelujah?(took me long enough)💜

None of my posts are intended as medical advice.  Please discuss any decisions about your medical care with a knowledgeable medical provider.  My success story:  Blue skies ahead, clear sailing

 

Posted

Thanks so much for checking back in. I will definitely get to the notes — it did seem a bit overwhelming but I can absolutely see the value. 

 

I’m feeling a bit frustrated because it seems like COVID basically reversed a huge amount of progress I had made and I now feel like I’ve gone backwards in my symptoms. It’s not only the fatigue, it’s intermittent low grade fever,  vertigo, loss of appetite, depressive symptoms, anxiety, and the crippling brain fog. Out of nowhere last night, some muscles in my lip began twitching for about an hour. In my most optimistic moments, I try to imagine that the COVID basically just precipitated a new wave, which I just need to ride out, and which will be over soon, as all waves inevitably are. Because this feels less like a brand-new, discrete thing (“long COVID”) and more a return and amplification of the WD. 

 

Have you seen other people temporarily set back in their WD journey by COVID? 

I’ve begun to experiment with adding back some magnesium to my daily regimen — a small dose at night before bed, 240mg I believe. I am hopeful that will help at least a little with the anxiety and muscle twitching. 

1997-2019: Paxil (20mg), eventually pooped out; 2000-present: Wellbutrin (300mg); 

Sept - Nov, 2019: Bridged from Paxil to Prozac (20mg). Many withdrawal symptoms but manageable. 

Nov, 2019 - Jan, 2020: Fast taper of Prozac and Wellbutrin. Few symptoms. 

Mar, 2020Terrible depression. Reinstated both Prozac (at 15mg) and Wellbutrin. 

Nov, 2020: Prozac seemingly not effective (still depressed, brain fog), switched to Cymbalta. 

Dec, 2020: Cymbalta not effective, reinstated Prozac. Major symptoms began around here: depression, anxiety, brain fog.

Jan, 2021: Switched from Prozac to Trintellix. Symptoms greatly worsened. 

Mar, 2021: Reinstated Prozac. Symptoms abated somewhat but never entirely. Fatigue grew worse from this point on. 

Aug, 2021: Ketamine infusions. Little if any effect. 

Jul - Oct 2022: Began slow taper of Prozac from 15mg. Currently at 12mg. 

 

 

  • Moderator Emeritus
Posted
On 11/7/2022 at 7:56 AM, Boone said:

In my most optimistic moments, I try to imagine that the COVID basically just precipitated a new wave, which I just need to ride out, and which will be over soon, as all waves inevitably are. Because this feels less like a brand-new, discrete thing (“long COVID”) and more a return and amplification of the WD. 

 

Have you seen other people temporarily set back in their WD journey by COVID? 

I’ve begun to experiment with adding back some magnesium to my daily regimen — a small dose at night before bed, 240mg I believe. I am hopeful that will help at least a little with the anxiety and muscle twitching. 

 

Oh Boone,

That may well be.  You shall be an expert wave surfer!

Yes....I believe I have, seen some......set back.....by COVID.  No doubt.

 

Excellent idea with the magnesium.  You may want to experiment with spreading it out throughout the day as well.  I did 250 mg of the capsule contents of magnesium citrate, sprinkled in a liter of water and sipped throughout the day with good calming response.  It was a bit chunky, not fully dissolved, but with a good shake before sipping it worked out well.

Also, I still have a Magnesium glycinate 400 mg powder, made for dilution.....with kind of a lemony flavor. 

Always take Magnesium with plenty of water.

Check the product labels carefully too, so you know and avoid other additives.

And here's that mammoth link, do just try to read the first and successive posts right after.  Then maybe more recent posts.  Whatever works best for you to find what you need.

-magnesium-natures-calcium-channel-blocker/

 

Do please try on the NOTES, when able okay?  Give me a tag or @ notification when you do so.  Thank you.

 

Best, I see healing on the horizon for your COVID and windows to relax in.

 

L, P, H, and G,

mmt

 

Late 2023- gone to emeritus status, inactive, don't @ me, I can check who I've posted on, and I'm not really here like I used to be......thanks.

Started with psycho meds/psychiatric care circa 1988.  In retrospect, and on contemplation, situational overwhelm.

Rounding up to 30 years of medications(30 medication trials, poly-pharmacy maximum was 3 at one time).

5/28/2015-off Adderal salts 2.5mg. (I had been on that since hospital 10/2014)

12/2015---just holding, holding, holding, with trileptal/oxcarb at 75 mg. 1/2 tab at hs.  My last psycho med ever!  Tapered @ 10% every 4 weeks, sometimes 2 weeks to

2016 Dec 16 medication free!!

Longer signature post here, with current supplements.

Herb and alcohol free since 5/15/2016.  And.....I quit smoking 11/2021. Lapsed.  Redo of quit smoking 9/28/2022, and again finally 5/25/24.  Can you say Hallelujah?(took me long enough)💜

None of my posts are intended as medical advice.  Please discuss any decisions about your medical care with a knowledgeable medical provider.  My success story:  Blue skies ahead, clear sailing

 

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now
×
×
  • Create New...

Important Information

Terms of Use Privacy Policy