Sarath Posted November 2, 2022 Posted November 2, 2022 In 2012 I was diagnosed as having depression. Dr prescribed me seroquel. Starting dose was 25mg. After taking this I got anger issues& gets irritated easily. So I tried to quit at 2015myself bt I couldn't. But dr increased my dosage till 100mg . Then I consulted Ayurveda hospitals but that too didn't work for me. Then upto 2019 I continued seroquel &I stopped . But I got severe withdrawal symptoms including insomnia, anxiety ,hypersensitivity etc. So I visited another psychiatrist but they gave me medicine for anxiety issues (NEXITO 10mg). So I took for one day & didn't worked from second day, so I stopped. Again I consulted another psychiatrist and he gave me OLANZAPINE. It was effective for one day and no longer effective from the second day. Then in 2021 I reinstated seroquel 25mg but it was overdose for me that I didn't know.Then the very Next day seroquel 25mg was no longer effective for me so I increased my dosage to 50mg . Then after 3 days 50mg was no longer effective and I increased to 75mg. Within 2 weeks I reached upto 200mg.But still 200mg is not so effective for me but I didn't want to increase further . About before a month I stopped completely .But due to withdrawal symptoms i restarted 25mg of seroquel 1 week back but didnt feel any effects at all so i stop. I think my brain receptors are downregulated. What to do? 2012-2019 Quetiapine 18/5/2021-Nexito 10mg for 2 days 5/8/2021-Quetiapine25mg within 2 weeks reached 200mg then tapered down to 50mg&stopped in 24/3/2022 25/3/2022 olanzapine for 2 days 27/3/2022- Quetiapine reinstate at 50mg then tapered down to zero at 20/9/2022 1/11/2022 Quetiapine reinstate 25mg no effects so stopped that day itself
Administrator Altostrata Posted November 5, 2022 Administrator Posted November 5, 2022 (edited) Welcome, @Sarath As I understand it, you have been taking Seroquel for the better part of 10 years. When did you start taking 25mg again? What are the withdrawal symptoms you experienced? What are your most prominent symptoms now. To help us out, follow these instructions Please summarize your drug and withdrawal history in your signature. You may need to use a computer to do this. How to List Your Drug History in Your Signature Edited November 18, 2022 by getofflex This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner. "It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein All postings © copyrighted.
Sarath Posted November 9, 2022 Author Posted November 9, 2022 Hi,thank you for your reply. Current symptoms Insomnia,Mood instability,irritability,anger and memory issues,attention problem,anhedonia,low energy,depression,anxiety issues,become an introvert etc Previous wd symptoms:hypersensitivty,allergy,insomnia,low energy,fever,hypotension,gi issues,eye sight problem,cognitive issues,fatty liver ,personality changes, anxeity etc 2012-2019 Quetiapine 18/5/2021-Nexito 10mg for 2 days 5/8/2021-Quetiapine25mg within 2 weeks reached 200mg then tapered down to 50mg&stopped in 24/3/2022 25/3/2022 olanzapine for 2 days 27/3/2022- Quetiapine reinstate at 50mg then tapered down to zero at 20/9/2022 1/11/2022 Quetiapine reinstate 25mg no effects so stopped that day itself
Administrator Altostrata Posted November 11, 2022 Administrator Posted November 11, 2022 You've only been taking 25mg for 10 days, correct? Have any symptoms reduced since you started it November 1? This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner. "It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein All postings © copyrighted.
Sarath Posted November 13, 2022 Author Posted November 13, 2022 Hi,I had reinstated 25mg just for one day and stopped that day itself because i didnt have any effect of having that. 2012-2019 Quetiapine 18/5/2021-Nexito 10mg for 2 days 5/8/2021-Quetiapine25mg within 2 weeks reached 200mg then tapered down to 50mg&stopped in 24/3/2022 25/3/2022 olanzapine for 2 days 27/3/2022- Quetiapine reinstate at 50mg then tapered down to zero at 20/9/2022 1/11/2022 Quetiapine reinstate 25mg no effects so stopped that day itself
Administrator Altostrata Posted November 16, 2022 Administrator Posted November 16, 2022 You would have to take the 25mg for at least several days to see what effect it has. Has your symptom pattern changed over the last few days? This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner. "It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein All postings © copyrighted.
Sarath Posted November 16, 2022 Author Posted November 16, 2022 Hi, i didnt feel any effect on my body and no reduction in side effects too. 2012-2019 Quetiapine 18/5/2021-Nexito 10mg for 2 days 5/8/2021-Quetiapine25mg within 2 weeks reached 200mg then tapered down to 50mg&stopped in 24/3/2022 25/3/2022 olanzapine for 2 days 27/3/2022- Quetiapine reinstate at 50mg then tapered down to zero at 20/9/2022 1/11/2022 Quetiapine reinstate 25mg no effects so stopped that day itself
Administrator Altostrata Posted November 17, 2022 Administrator Posted November 17, 2022 Do you still have these withdrawal symptoms? On 11/9/2022 at 10:33 AM, Sarath said: Hi,thank you for your reply. Current symptoms Insomnia,Mood instability,irritability,anger and memory issues,attention problem,anhedonia,low energy,depression,anxiety issues,become an introvert etc Previous wd symptoms:hypersensitivty,allergy,insomnia,low energy,fever,hypotension,gi issues,eye sight problem,cognitive issues,fatty liver ,personality changes, anxeity etc Reinstatement of the drug is the only known way to reduce the withdrawal symptoms. You might find that if you took a half-tablet of 12.5mg every day, it may reduce your withdrawal symptoms. Your decision whether you want to do this or deal with withdrawal symptoms for a while. This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner. "It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein All postings © copyrighted.
Sarath Posted November 17, 2022 Author Posted November 17, 2022 Hi, Since quetiapine has no effects on me i want to stop this medication.if i continue to deal with my current symptoms without quetiapine, how long it will take to get normal? 2012-2019 Quetiapine 18/5/2021-Nexito 10mg for 2 days 5/8/2021-Quetiapine25mg within 2 weeks reached 200mg then tapered down to 50mg&stopped in 24/3/2022 25/3/2022 olanzapine for 2 days 27/3/2022- Quetiapine reinstate at 50mg then tapered down to zero at 20/9/2022 1/11/2022 Quetiapine reinstate 25mg no effects so stopped that day itself
Administrator Altostrata Posted November 17, 2022 Administrator Posted November 17, 2022 That is unknown. Could be months. This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner. "It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein All postings © copyrighted.
Sarath Posted November 19, 2022 Author Posted November 19, 2022 Hi,Quetiapine doesnt help with my withdrawal symptoms especially insomnia and it doesnt have any effects on me.Is this tachyphylaxis?should i continue to take this medicine or what should i do ? 2012-2019 Quetiapine 18/5/2021-Nexito 10mg for 2 days 5/8/2021-Quetiapine25mg within 2 weeks reached 200mg then tapered down to 50mg&stopped in 24/3/2022 25/3/2022 olanzapine for 2 days 27/3/2022- Quetiapine reinstate at 50mg then tapered down to zero at 20/9/2022 1/11/2022 Quetiapine reinstate 25mg no effects so stopped that day itself
Administrator Altostrata Posted November 20, 2022 Administrator Posted November 20, 2022 How long have you been taking 25mg quetiapine? This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner. "It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein All postings © copyrighted.
Sarath Posted November 20, 2022 Author Posted November 20, 2022 Hi,since November 1 2012-2019 Quetiapine 18/5/2021-Nexito 10mg for 2 days 5/8/2021-Quetiapine25mg within 2 weeks reached 200mg then tapered down to 50mg&stopped in 24/3/2022 25/3/2022 olanzapine for 2 days 27/3/2022- Quetiapine reinstate at 50mg then tapered down to zero at 20/9/2022 1/11/2022 Quetiapine reinstate 25mg no effects so stopped that day itself
Administrator Altostrata Posted November 20, 2022 Administrator Posted November 20, 2022 You have been taking 25mg quetiapine every day since November 1? How has your symptom pattern changed in the last week? This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner. "It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein All postings © copyrighted.
Sarath Posted November 22, 2022 Author Posted November 22, 2022 No there is no change. 2012-2019 Quetiapine 18/5/2021-Nexito 10mg for 2 days 5/8/2021-Quetiapine25mg within 2 weeks reached 200mg then tapered down to 50mg&stopped in 24/3/2022 25/3/2022 olanzapine for 2 days 27/3/2022- Quetiapine reinstate at 50mg then tapered down to zero at 20/9/2022 1/11/2022 Quetiapine reinstate 25mg no effects so stopped that day itself
Administrator Altostrata Posted November 22, 2022 Administrator Posted November 22, 2022 Which of these have gotten better or worse? On 11/9/2022 at 10:33 AM, Sarath said: Current symptoms Insomnia,Mood instability,irritability,anger and memory issues,attention problem,anhedonia,low energy,depression,anxiety issues,become an introvert etc This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner. "It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein All postings © copyrighted.
Sarath Posted January 23, 2023 Author Posted January 23, 2023 No change at all 2012-2019 Quetiapine 18/5/2021-Nexito 10mg for 2 days 5/8/2021-Quetiapine25mg within 2 weeks reached 200mg then tapered down to 50mg&stopped in 24/3/2022 25/3/2022 olanzapine for 2 days 27/3/2022- Quetiapine reinstate at 50mg then tapered down to zero at 20/9/2022 1/11/2022 Quetiapine reinstate 25mg no effects so stopped that day itself
Sarath Posted January 23, 2023 Author Posted January 23, 2023 Its been 3months since i quit quetiapine. Still there is no change from withdrawal symptoms. Is it tachyphylaxis ? Whether i should start another drug or wait somedays and then reinstating quetiapine 2012-2019 Quetiapine 18/5/2021-Nexito 10mg for 2 days 5/8/2021-Quetiapine25mg within 2 weeks reached 200mg then tapered down to 50mg&stopped in 24/3/2022 25/3/2022 olanzapine for 2 days 27/3/2022- Quetiapine reinstate at 50mg then tapered down to zero at 20/9/2022 1/11/2022 Quetiapine reinstate 25mg no effects so stopped that day itself
Administrator Altostrata Posted January 26, 2023 Administrator Posted January 26, 2023 On 11/16/2022 at 11:15 PM, Altostrata said: Reinstatement of the drug is the only known way to reduce the withdrawal symptoms. You might find that if you took a half-tablet of 12.5mg every day, it may reduce your withdrawal symptoms. Your decision whether you want to do this or deal with withdrawal symptoms for a while. This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner. "It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein All postings © copyrighted.
Sarath Posted February 8, 2023 Author Posted February 8, 2023 Hi,i had reinstated quetiapine for 3 days and there is no change in withdrawal symptoms.Then i consulted a psychiatrist and he prescribed me olanzapine and it reduced my withdrawal symptoms about 50% . Should i continue olanzapine or wait for few days and reinstated quetiapine? 2012-2019 Quetiapine 18/5/2021-Nexito 10mg for 2 days 5/8/2021-Quetiapine25mg within 2 weeks reached 200mg then tapered down to 50mg&stopped in 24/3/2022 25/3/2022 olanzapine for 2 days 27/3/2022- Quetiapine reinstate at 50mg then tapered down to zero at 20/9/2022 1/11/2022 Quetiapine reinstate 25mg no effects so stopped that day itself
Moderator FireflyFyte Posted February 8, 2023 Moderator Posted February 8, 2023 55 minutes ago, Sarath said: Hi,i had reinstated quetiapine for 3 days and there is no change in withdrawal symptoms.Then i consulted a psychiatrist and he prescribed me olanzapine and it reduced my withdrawal symptoms about 50% . Should i continue olanzapine or wait for few days and reinstated quetiapine? I am not a moderator but ended up on Olanzapine after a terrible withdrawal from Latuda. How long have you been on the Olanzapine? If it's helping, I would stay on the Olanzapine, stabilize, and then begin a very slow taper of no more than 10% per month. 1 Pre- October 2022: Wellbutrin, Escitalopram, Citalopram, Sertraline, Adderall IR, Vyvanse, Propranolol, Buspar, Ativan, and Latuda Oct 13, 2022 - Oct 24, 2022 and Oct 31, 2022 - Present: Zyprexa (2.5 mg). Jan 29, 2023 = 2.375mg -> Jan 22, 2024 = 0.97mg -> Jan 14, 2025 = 0.25mg Oct 14, 2022 - Present: Prozac (40mg) upped from 20mg on Nov 1, 2022. Oct 31, 2022 - Present: Gabapentin (300mg 3x day) -> May 3, 2023 = 300mg 2x day -> Jan 7, 2024 = 400mg
Mentor littlebird Posted February 8, 2023 Mentor Posted February 8, 2023 Just popping in to say I hope you feel better soon! Pronouns: they/them/theirs Started on Prozac in early 2000s to treat cPTSD, been on various cocktails ever since. 2002-2004, 2017-2022: Buspar, tapered down to 0 2016-present: 100mg Seroquel for sleep -> May 2023: 90mg -> June 2023: 81mg -> September 2023: 72mg -> switched to brand name, much too strong, down to 60mg -> October 2023: 54mg -> November 2023: 50mg -> January 2024: 45mg -> April 2024: 40.5mg -> May 2024: 41mg -> June 2024: 35mg -> July 2024: 31mg -> August 2024: 28mg -> September 2024: 25mg 2016-Present: 100mg Wellbutrin SR -> January 2023: 75mg IR (37.5mg 2x a day, a mistake, don't replicate) -> February 2023 (33.75mg 2x a day) -> July 2023 (30.37mg 2x a day) -> August 2023: 25mg 2x a day -> October 2024: 22mg 2x a day 2018-present: 25mg Pristiq 2015-present: 600mg Gabapentin (200mg 3x a day) -> December 2022: 300mg Gabapentin (100mg 3x a day) per GP's recommendation after side effects -> March 2023: 90mg 3x a day (switched to liquid suspension) -> April 2023: 81mg 3x a day -> September 2023: bad generic, switched back to homemade liquid; too strong after bad generic, down to 70mg 3x a day, still bad. Adjusted slowly till at 60mg 3x a day, much better. Long hold till -> December 2023: 54mg, still feels too high after November Seroquel switch from brand name to generic, doc recommended 50mg which feels better -> January 2024: When Wellbutrin went down, Gabapentin started putting me to sleep, went down to 45mg, then 41mg to stay awake, so far so good -> February 2024: 36mg, still too high, 34mg -> March 2024: 31mg, STILL too high, 30mg down to 25mg Supplements: Multivitamin w/magnesium, probiotics, digestive enzymes, anti-viral nitric oxide nose spray as needed
Administrator Altostrata Posted February 9, 2023 Administrator Posted February 9, 2023 If you feel better, we don't argue with that. What are this psychiatrist's plans for tapering olanzapine? This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner. "It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein All postings © copyrighted.
Sarath Posted February 9, 2023 Author Posted February 9, 2023 I had olanzapine for 1 week and it reduced my anxiety a little bit bt no changes in any other withdrawal symptoms . But after 1 week there is no effects on having olanzapine similar like qutipine .Is it tachyphylaxis ? 2012-2019 Quetiapine 18/5/2021-Nexito 10mg for 2 days 5/8/2021-Quetiapine25mg within 2 weeks reached 200mg then tapered down to 50mg&stopped in 24/3/2022 25/3/2022 olanzapine for 2 days 27/3/2022- Quetiapine reinstate at 50mg then tapered down to zero at 20/9/2022 1/11/2022 Quetiapine reinstate 25mg no effects so stopped that day itself
Administrator Altostrata Posted February 9, 2023 Administrator Posted February 9, 2023 If you are seeking additional drug treatment, please talk to your prescriber. We do not provide counseling for new drug treatment here. We don't know of any miracle solution to withdrawal syndrome. Reinstatement of a low dose of the original drug is the most reliable option, but it may not immediately reverse withdrawal. As explained earlier about your attempt to reinstate quetiapine: On 11/15/2022 at 11:23 PM, Altostrata said: You would have to take the 25mg for at least several days to see what effect it has. At this point, you might try reinstating 10mg quetiapine and see if that helps. This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner. "It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein All postings © copyrighted.
Sarath Posted February 12, 2023 Author Posted February 12, 2023 I had 10mg quetiapine, and it seems to be no longer effective.should i take drug holiday or what else should i do? 2012-2019 Quetiapine 18/5/2021-Nexito 10mg for 2 days 5/8/2021-Quetiapine25mg within 2 weeks reached 200mg then tapered down to 50mg&stopped in 24/3/2022 25/3/2022 olanzapine for 2 days 27/3/2022- Quetiapine reinstate at 50mg then tapered down to zero at 20/9/2022 1/11/2022 Quetiapine reinstate 25mg no effects so stopped that day itself
Administrator Altostrata Posted February 13, 2023 Administrator Posted February 13, 2023 10 hours ago, Sarath said: I had 10mg quetiapine, and it seems to be no longer effective.should i take drug holiday or what else should i do? When did you take 10mg quetiapine? This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner. "It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein All postings © copyrighted.
Sarath Posted February 13, 2023 Author Posted February 13, 2023 Im taking for 3 days. 2012-2019 Quetiapine 18/5/2021-Nexito 10mg for 2 days 5/8/2021-Quetiapine25mg within 2 weeks reached 200mg then tapered down to 50mg&stopped in 24/3/2022 25/3/2022 olanzapine for 2 days 27/3/2022- Quetiapine reinstate at 50mg then tapered down to zero at 20/9/2022 1/11/2022 Quetiapine reinstate 25mg no effects so stopped that day itself
Administrator Altostrata Posted February 13, 2023 Administrator Posted February 13, 2023 What do you mean, "no longer effective"? On 11/2/2022 at 1:50 AM, Sarath said: But due to withdrawal symptoms i restarted 25mg of seroquel 1 week back but didnt feel any effects at all so i stop. What were the withdrawal symptoms you had after September 9, 2022, when you went off quetiapine again? This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner. "It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein All postings © copyrighted.
Sarath Posted February 14, 2023 Author Posted February 14, 2023 Usually quetiapine uplift my mood and helps me to get deep sleep.Bt now i didnt have any feeling of taking it. Actually i reinstated quitiapine so to reduce my withdrawal symptoms. But when i had taken there was no change in that and it remain the same through the period . It didnt help me in dealing with withdrawal symptoms so no effective 2012-2019 Quetiapine 18/5/2021-Nexito 10mg for 2 days 5/8/2021-Quetiapine25mg within 2 weeks reached 200mg then tapered down to 50mg&stopped in 24/3/2022 25/3/2022 olanzapine for 2 days 27/3/2022- Quetiapine reinstate at 50mg then tapered down to zero at 20/9/2022 1/11/2022 Quetiapine reinstate 25mg no effects so stopped that day itself
Administrator Altostrata Posted February 15, 2023 Administrator Posted February 15, 2023 8 hours ago, Sarath said: Actually i reinstated quitiapine so to reduce my withdrawal symptoms. What were your withdrawal symptoms? This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner. "It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein All postings © copyrighted.
Sarath Posted February 15, 2023 Author Posted February 15, 2023 Insomnia,OCD,dementia,emotional blunting,feeling disconnected,Twitching,irritated,no sex drive,ED,no motivation,low energy,low mood. 2012-2019 Quetiapine 18/5/2021-Nexito 10mg for 2 days 5/8/2021-Quetiapine25mg within 2 weeks reached 200mg then tapered down to 50mg&stopped in 24/3/2022 25/3/2022 olanzapine for 2 days 27/3/2022- Quetiapine reinstate at 50mg then tapered down to zero at 20/9/2022 1/11/2022 Quetiapine reinstate 25mg no effects so stopped that day itself
Administrator Altostrata Posted February 15, 2023 Administrator Posted February 15, 2023 How are you taking 10mg quetiapine? Are you using a liquid? What time o'clock do you take it? How do you feel after you take it compared to how you feel before you take it? This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner. "It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein All postings © copyrighted.
Sarath Posted February 16, 2023 Author Posted February 16, 2023 Initially i was taking it as oral tablets.Then i found it no more effective i tried it as liquid solution too.Usually i take at 10PM but there was no effect so i take it whenever im sleepy.Sometimes i feel sleepy only at morming so i take it at that time.Initial days,i take it as a sleep aid and it helps me to sleep but now it was not effective at all. 2012-2019 Quetiapine 18/5/2021-Nexito 10mg for 2 days 5/8/2021-Quetiapine25mg within 2 weeks reached 200mg then tapered down to 50mg&stopped in 24/3/2022 25/3/2022 olanzapine for 2 days 27/3/2022- Quetiapine reinstate at 50mg then tapered down to zero at 20/9/2022 1/11/2022 Quetiapine reinstate 25mg no effects so stopped that day itself
Administrator Altostrata Posted February 16, 2023 Administrator Posted February 16, 2023 Are you making your own liquid? How long have you been taking it as a liquid? It's important that you take quetiapine at the same times each day. Inconsistent dosing might be why it doesn't "work". This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner. "It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein All postings © copyrighted.
Sarath Posted February 17, 2023 Author Posted February 17, 2023 I dilute quetiapine tablet into a solution. 2012-2019 Quetiapine 18/5/2021-Nexito 10mg for 2 days 5/8/2021-Quetiapine25mg within 2 weeks reached 200mg then tapered down to 50mg&stopped in 24/3/2022 25/3/2022 olanzapine for 2 days 27/3/2022- Quetiapine reinstate at 50mg then tapered down to zero at 20/9/2022 1/11/2022 Quetiapine reinstate 25mg no effects so stopped that day itself
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