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Saphriskill: Tapering off Saphris


Saphriskill

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Posted

I have been on various antipsychotics since 2016.

I've been on Saphris for almost a year, and I am taking 3/4 of 5mg tablet currently.

I'm determined to come off antipsychotics eventually.

However, I would like to stay on 3/4 tablet until mid-April because I expect some changes in my life.

I don't know how to taper off Saphris because it can't be dissolved in water.

I am splitting my medication but I don't use scale to measure the dosage.

 

Edit: I don't know how to add my medical history.

 

Invega 3mg escotalopram 10mg - 2016-2018

 

Risperidone 1.5mg 2018- 2019

 

Latuda 2019- 2020

 

Risperidone 1.5mg  end of 2020- early 2022

 

Saphris 5mg February 2022(current medication)-  3.75mg(February 2023)

  • Moderator Emeritus
Posted

Welcome to SA, Saphriskill.

 

You can use the following link to post your drug signature (drug history)--doses, dates, and discontinuations & reinstatements, in the last 12-24 months particularly.

 

Account Settings – Create or Edit a signature.

 

The only way to taper Saphris is by reducing the tablet.  To get consistent and accurate doses it's much better to use a digital scale rather than just cutting tablets.  Many members use the Smart Weigh digital scale, available on Amazon.  Here's the link:

 

Amazon.com: Smart Weigh: All Scales

 

The following link is about tapering Saphris

 

Tips for tapering off asenapine (Saphris) - Tapering

 

We don't recommend a lot of supplements on SA, as many members report being sensitive to them due to our over-reactive nervous systems, but two supplements that we do recommend are magnesium (glycinate is a good form) and omega 3 (fish oil). Many people find these to be calming to the nervous system. 

 

Magnesium, nature's calcium channel blocker 

 

Omega-3 fatty acids (fish oil) 

 

Add in one at a time and at a low dose in case you do experience problems.

 

This is your introduction topic -- the place for you to ask questions, record symptoms, share your progress, and connect with other members of the SA community.  I hope you’ll find the information in the SA forums helpful for your situation.  I'm sorry that you are in the position that you need the information, but I am glad that you found us.

 

Gridley Introduction

 

Lexapro 20 mg since 2004.  Begin Brassmonkey Slide Taper Jan. 2017.   

End 2017 year 1 of taper at 9.25mg 

End 2018 year 2 of taper at 4.1mg

End 2019 year 3 of taper at 1.0mg  

Oct. 30, 2020  Jump to zero from 0.025mg.  Current dose: 0.000mg

3 year, 10 month taper is 100% complete.

 

Ativan 1 mg to 1.875mg 1986-2020, two CT's and reinstatements

Nov. 2020, 7-week Ativan-Valium crossover to 18.75mg Valium

Feb. 2021, begin 10%/4 week taper of 18.75mg Valium 

End 2021  year 1 of Valium taper at 6mg

End 2022 year 2 of Valium taper at 2.75mg 

End 2023 year 3 of Valium taper at 1mg

Jan. 24, 2024: Hold at 1mg and shift to Imipramine taper.

Taper is 95% complete.

 

Imipramine 75 mg daily since 1986.  Jan.-Sept. 2016 tapered to 14.4mg  

March 22, 2022: Begin 10%/4 week taper

Aug. 5, 2022: hold at 9.5mg and shift to Valium taper

Jan. 24, 2024: Resume Imipramine taper.  Current dose as of Dec 28: 2.2mg

Taper is 97% complete.  

  

Supplements: multiple, quercetin, omega-3, vitamins C, E and D3, magnesium glycinate, probiotic, zinc, melatonin .3mg, iron, serrapeptase, nattokinase, L-Glutamine, milk thistle, choline


I am not a medical professional and this is not medical advice. It is information based on my own experience as well as that of other members who have survived these drugs.

  • Mentor
Posted
19 hours ago, Saphriskill said:

I am splitting my medication but I don't use scale to measure the dosage.

 

Hello and welcome! Just popping in to say that I had a huge difference when I started using a high quality scale to measure my meds. I thought at low doses it wouldn’t matter than much if I eyeballed it. When I started measuring, I started feeling a lot more steady.

 

There’s a learning curve to it, especially when it comes to fillers in meds, but it helps so much. I learned the hard way not to try a discount scale, and returned it to get the recommended Gemini 20 Scale. It’s much more exact, and worth the investment. Can’t tell you how much it helped to get exact!

Pronouns: they/them/theirs 

Started on Prozac in early 2000s to treat cPTSD, been on various cocktails ever since.

2002-2004, 2017-2022: Buspar, tapered down to 0

2016-present: 100mg Seroquel for sleep -> May 2023: 90mg -> June 2023: 81mg -> September 2023: 72mg -> switched to brand name, much too strong, down to 60mg -> October 2023: 54mg -> November 2023: 50mg -> January 2024: 45mg -> April 2024: 40.5mg -> May 2024: 41mg -> June 2024: 35mg -> July 2024: 31mg -> August 2024: 28mg -> September 2024: 25mg

2016-Present: 100mg Wellbutrin SR -> January 2023: 75mg IR (37.5mg 2x a day, a mistake, don't replicate) -> February 2023 (33.75mg 2x a day) -> July 2023 (30.37mg 2x a day) -> August 2023: 25mg 2x a day -> October 2024: 22mg 2x a day

2018-present: 25mg Pristiq

2015-present: 600mg Gabapentin (200mg 3x a day) -> December 2022: 300mg Gabapentin (100mg 3x a day) per GP's recommendation after side effects -> March 2023: 90mg 3x a day (switched to liquid suspension) -> April 2023: 81mg 3x a day -> September 2023: bad generic, switched back to homemade liquid; too strong after bad generic, down to 70mg 3x a day, still bad. Adjusted slowly till at 60mg 3x a day, much better. Long hold till -> December 2023: 54mg, still feels too high after November Seroquel switch from brand name to generic, doc recommended 50mg which feels better -> January 2024: When Wellbutrin went down, Gabapentin started putting me to sleep, went down to 45mg, then 41mg to stay awake, so far so good -> February 2024: 36mg, still too high, 34mg -> March 2024: 31mg, STILL too high, 30mg down to 25mg

Supplements: Multivitamin w/magnesium, probiotics, digestive enzymes, anti-viral nitric oxide nose spray as needed

  • 2 weeks later...
Posted
On 1/30/2023 at 2:01 PM, Gridley said:

Welcome to SA, Saphriskill.

 

You can use the following link to post your drug signature (drug history)--doses, dates, and discontinuations & reinstatements, in the last 12-24 months particularly.

 

Account Settings – Create or Edit a signature.

 

The only way to taper Saphris is by reducing the tablet.  To get consistent and accurate doses it's much better to use a digital scale rather than just cutting tablets.  Many members use the Smart Weigh digital scale, available on Amazon.  Here's the link:

 

Amazon.com: Smart Weigh: All Scales

 

The following link is about tapering Saphris

 

Tips for tapering off asenapine (Saphris) - Tapering

 

We don't recommend a lot of supplements on SA, as many members report being sensitive to them due to our over-reactive nervous systems, but two supplements that we do recommend are magnesium (glycinate is a good form) and omega 3 (fish oil). Many people find these to be calming to the nervous system. 

 

Magnesium, nature's calcium channel blocker 

 

Omega-3 fatty acids (fish oil) 

 

Add in one at a time and at a low dose in case you do experience problems.

 

This is your introduction topic -- the place for you to ask questions, record symptoms, share your progress, and connect with other members of the SA community.  I hope you’ll find the information in the SA forums helpful for your situation.  I'm sorry that you are in the position that you need the information, but I am glad that you found us.

 

Thank you for the reply.

I started using pill cutter, and I think I really need to use scale to be stabilized.

I have had semi depression for almost 3 weeks since I was not motivated to do anything.

I was not motivated to do my school work but I also didn't know if I could handle any types of work during withdrawl process.

This is the reason for delayed response.

Invega 3mg escotalopram 10mg - 2016-2018

 

Risperidone 1.5mg 2018- 2019

 

Latuda 2019- 2020

 

Risperidone 1.5mg  end of 2020- early 2022

 

Saphris 5mg February 2022(current medication)-  3.75mg(February 2023)

  • Moderator Emeritus
Posted
Just now, Saphriskill said:

I think I really need to use scale to be stabilized.

It's very important to get a consistent, accurate dose.  As @littlebird noted, the Gemini-20 scale (now called the Smart Weigh scale) works very well.

Gridley Introduction

 

Lexapro 20 mg since 2004.  Begin Brassmonkey Slide Taper Jan. 2017.   

End 2017 year 1 of taper at 9.25mg 

End 2018 year 2 of taper at 4.1mg

End 2019 year 3 of taper at 1.0mg  

Oct. 30, 2020  Jump to zero from 0.025mg.  Current dose: 0.000mg

3 year, 10 month taper is 100% complete.

 

Ativan 1 mg to 1.875mg 1986-2020, two CT's and reinstatements

Nov. 2020, 7-week Ativan-Valium crossover to 18.75mg Valium

Feb. 2021, begin 10%/4 week taper of 18.75mg Valium 

End 2021  year 1 of Valium taper at 6mg

End 2022 year 2 of Valium taper at 2.75mg 

End 2023 year 3 of Valium taper at 1mg

Jan. 24, 2024: Hold at 1mg and shift to Imipramine taper.

Taper is 95% complete.

 

Imipramine 75 mg daily since 1986.  Jan.-Sept. 2016 tapered to 14.4mg  

March 22, 2022: Begin 10%/4 week taper

Aug. 5, 2022: hold at 9.5mg and shift to Valium taper

Jan. 24, 2024: Resume Imipramine taper.  Current dose as of Dec 28: 2.2mg

Taper is 97% complete.  

  

Supplements: multiple, quercetin, omega-3, vitamins C, E and D3, magnesium glycinate, probiotic, zinc, melatonin .3mg, iron, serrapeptase, nattokinase, L-Glutamine, milk thistle, choline


I am not a medical professional and this is not medical advice. It is information based on my own experience as well as that of other members who have survived these drugs.

Posted
On 1/30/2023 at 3:43 PM, littlebird said:

 

Hello and welcome! Just popping in to say that I had a huge difference when I started using a high quality scale to measure my meds. I thought at low doses it wouldn’t matter than much if I eyeballed it. When I started measuring, I started feeling a lot more steady.

 

There’s a learning curve to it, especially when it comes to fillers in meds, but it helps so much. I learned the hard way not to try a discount scale, and returned it to get the recommended Gemini 20 Scale. It’s much more exact, and worth the investment. Can’t tell you how much it helped to get exact!

 

Sorry for the delayed response.

Thank you for your advice!

I am stabilized on 3/4 tablet currently, and I am going to buy a scale you mentioned to have a steady withdrawal process.

My psychiatrist added Lexapro after I told him that I had anxiety attack for stopping Saphris cold turkey.

 

I think Lexapro might be helpful for tapering Saphris but I don't want another brutal withdrawl process.

 

I am in mu 20s, and there are many years left behind. I want to live a life without taking any more neurotoxin.

Invega 3mg escotalopram 10mg - 2016-2018

 

Risperidone 1.5mg 2018- 2019

 

Latuda 2019- 2020

 

Risperidone 1.5mg  end of 2020- early 2022

 

Saphris 5mg February 2022(current medication)-  3.75mg(February 2023)

  • Moderator Emeritus
Posted
20 minutes ago, Saphriskill said:

I think Lexapro might be helpful for tapering Saphris but I don't want another brutal withdrawl process.

I'm sorry to hear that your psychiatrist added Lexapro.  This is an extremely powerful SSRI drug, and can be very hard to get off of.  It takes only 4 weeks for your brain to adapt to Lexapro and become dependent on it.  If you just recently started the Lexapro, as in the past few days or week or 2, you can just stop it without tapering.  When did you start this Lexapro?  Please add this to your drug signature, thank you.  Psychiatrists are notorious for adding more drugs to patients, and this usually causes more problems than it solves.  Instead of helping with WD, it may just confuse your brain more to have more chemicals put in it.  Just FYI, it took me 5 years to taper off Lexapro, and it was very difficult.  I'm just trying to help you avoid big problems in the future.  

 

Your drug sig says "Saphris 5mg February 2022- till now". Please say the actual date, as we won't know what "till now" is.  

 

Psychiatrists MO is to add drugs.  You can recover without adding Lexapro or other drugs.  

Please do not private message me.  Only tag me for urgent questions about tapering and reinstating - thank you.  

 

***Please note this is not medical advice.  Discuss any decisions about your medical care with a doctor who understands psych meds and how to withdraw from them, if you can find one.

 

Lexapro   Started Apr 15 2010 - 10 mg;  started taper August 2017, recent taper info: Apr 2 '20  0.18 mg; Jul 16  0.17 mg, Aug 23  0.16 mg, Oct 7  0.15 mg, Nov 8 - 0.14, Jan 16 '21 - 0.13, Feb 7 - 0.12, Feb 22 - 0.11, Mar 26 - 0.10, May 21 - 0.09, June 15 - 0.08 Aug 16 - 0.07, Oct 6 - 0.06, Nov 21 0.05, Dec. 17 0.04, Jan 14 '22 0.03, Feb 19 0.02, Apr 18 0.01, May 15 0.005,  Jul 8, 0.00.  Psych Drug Free as of July 8, 2022!!  Woohoo!!!

other meds: Levothyroxine 75 mg

magnesium in small amounts at 4 AM, before bed

suppl AM: fish oil, flax oil, vit C, vit E, multivitamin, zinc

suppl 8 PM: magnesium 350 mg, extended release vitamin C, melatonin 2 mg

 

Paxil 2002 - 2010, switched to Lexapro 2010 

Trazodone 50 mg. 2002 - 2019, fast tapered in 2019 

Xanax 0.5 mg as needed 2002 - 2019, up to 3x weekly 

Posted
25 minutes ago, getofflex said:

I'm sorry to hear that your psychiatrist added Lexapro.  This is an extremely powerful SSRI drug, and can be very hard to get off of.  It takes only 4 weeks for your brain to adapt to Lexapro and become dependent on it.  If you just recently started the Lexapro, as in the past few days or week or 2, you can just stop it without tapering.  When did you start this Lexapro?  Please add this to your drug signature, thank you.  Psychiatrists are notorious for adding more drugs to patients, and this usually causes more problems than it solves.  Instead of helping with WD, it may just confuse your brain more to have more chemicals put in it.  Just FYI, it took me 5 years to taper off Lexapro, and it was very difficult.  I'm just trying to help you avoid big problems in the future.  

 

Your drug sig says "Saphris 5mg February 2022- till now". Please say the actual date, as we won't know what "till now" is.  

 

Psychiatrists MO is to add drugs.  You can recover without adding Lexapro or other drugs.  

 

I used to take Lexapro with Invega from 2016 to 2018. I had no adverse reaction to CT cause I was taking another antipsychotics.

This time is different. I am reducing antipsychotics and my body mechanism could have been changed for the past 6 years.

 

I have not reinstated Lexapro yet and I am taking  Saphris only.

 

Invega 3mg escotalopram 10mg - 2016-2018

 

Risperidone 1.5mg 2018- 2019

 

Latuda 2019- 2020

 

Risperidone 1.5mg  end of 2020- early 2022

 

Saphris 5mg February 2022(current medication)-  3.75mg(February 2023)

  • Moderator Emeritus
Posted
1 hour ago, Saphriskill said:

I have not reinstated Lexapro yet and I am taking  Saphris only.

That's good.  

 

Be aware that the more we go on and off drugs, the more sensitive our systems tend to become, and the harder it is to taper off the drugs.  

Please do not private message me.  Only tag me for urgent questions about tapering and reinstating - thank you.  

 

***Please note this is not medical advice.  Discuss any decisions about your medical care with a doctor who understands psych meds and how to withdraw from them, if you can find one.

 

Lexapro   Started Apr 15 2010 - 10 mg;  started taper August 2017, recent taper info: Apr 2 '20  0.18 mg; Jul 16  0.17 mg, Aug 23  0.16 mg, Oct 7  0.15 mg, Nov 8 - 0.14, Jan 16 '21 - 0.13, Feb 7 - 0.12, Feb 22 - 0.11, Mar 26 - 0.10, May 21 - 0.09, June 15 - 0.08 Aug 16 - 0.07, Oct 6 - 0.06, Nov 21 0.05, Dec. 17 0.04, Jan 14 '22 0.03, Feb 19 0.02, Apr 18 0.01, May 15 0.005,  Jul 8, 0.00.  Psych Drug Free as of July 8, 2022!!  Woohoo!!!

other meds: Levothyroxine 75 mg

magnesium in small amounts at 4 AM, before bed

suppl AM: fish oil, flax oil, vit C, vit E, multivitamin, zinc

suppl 8 PM: magnesium 350 mg, extended release vitamin C, melatonin 2 mg

 

Paxil 2002 - 2010, switched to Lexapro 2010 

Trazodone 50 mg. 2002 - 2019, fast tapered in 2019 

Xanax 0.5 mg as needed 2002 - 2019, up to 3x weekly 

  • 1 year later...
Posted

Hi @Saphriskill how are you going? i am currently at 2.5 mg of Saphris and currently waiting. Do you know how to taper with the scales? Can you please tell me? Cheers.

Escitalopram  approximately 2012 to March 31st 2023 20mg cold turkey.

Back on to escitalopram 10 mg approximately 3weeks later.

Switch to Fluoxetine approximately 3 weeks after that.

Come off Fluoxetine 20 mg 22nd of June cold turkey.

 

2018 Saphris 5mg, 2022 Nov upped to 15mg, March 2024 decreased to 10mg, in April started to drop by 2.5mg a month. Got to 2.5mg and went back up to 7.5mg due to possibly dopamine sensitivety or withdrawal but can be sure. Not sure if kindled or withdrawal of symptoms I'm getting.

 

Been on antipsychotics such as Serrequal, Abilify, Zyprexa, but can't remember dates.

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