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PearlsMom1979: Boiling Rage/Anger and Cognitive Decline


PearlsMom1979

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Thank you so much again @Barry2954

 

I was curious as I don't think anyone has ever reported such increase in appetite as symptom.

But anyways as we all know it's different for everyone, so we just have to wait it out.

 

Thanks again.

Fluxonine April 2021 to June 2021 

Lenzo 0.5 added in June 2021

Risperidone added in July 2021

Started with 0.5 ml risperidone, dose was increased by doctor upto 4 ml till we reached November 2021

Started tapering from January 2022 and completed taper in February 2023 with the guidance of doctor 

Drug free from 14th February 2023

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It might help to know that people with benzo withdrawal often have sugar cravings. Between that and the benzo induced vomiting and gallstone induced problems I was dependent upon pizza's, chocolate, and sweetened condensed milk, for years. As I have been recovering I am now pickling various foods with apple cider vinegar, using herbs and spices, have eliminated dairy and most sugars (I eliminated gluten more than a decade ago), and have been making good, though slow, progress at recovering. For me currently this is all about trying to repair my microbiome.

Prior medications;

sertraline 50mg April

sertraline 100mg May to July 2014 (ceased medication immediately upon occurrence of first thunderclap headache)

lorazepam April 2014 and November 2014 to January 2015 (each time suppressing symptoms of illness until two weeks after cessation of medication)

seroquel November 2014 to January 2015 50mg prior to being raised to 100mg for one day (medication ceased immediately upon occurrence of convulsive seizure)

warfarin 1990 to June 2023

Was instructed to 'cease doing anything healthy' by treating psychiatrist in June 2014 (the psychiatrist stating that belief in disease is the cause of disease and that dietary supplementation encourages people to think there's something wrong with us) so only commenced taking supplements again in June 2023 upon contrary instructions from GP.

 

Current medications;

eliquis since June 2023

Supplements; multivitamin/mineral, zinc, magnesium, calcium/magnesium, vitamin c, vitamin d, spirulina, resveratrol, iron.

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@Barry2954 thanks again.

 

It's not craving for any particular food. It's the constant urge to keep on eating. If she asks for chocolates and I tell her chocolate is finished, do you want some nuts, she will eat nuts without any fuss.

 

She demands non stop but in the situation when her food of choice is not available, she will agree to any alternative offered.

 

This is the way I am still trying to give her healthy replacements, thanking God for small favours...

 

Urges for some particular type of food during withdrawal, I do understand that. 

 

But it's not possible to feel hungry all the time. I really don't know what is happening here in our case , if this is a withdrawal symptom or she actually needs it.

 

Anyways cannot help it much, just waiting it to pass. And praying for you and all of us here 💕  ❤️ 

Fluxonine April 2021 to June 2021 

Lenzo 0.5 added in June 2021

Risperidone added in July 2021

Started with 0.5 ml risperidone, dose was increased by doctor upto 4 ml till we reached November 2021

Started tapering from January 2022 and completed taper in February 2023 with the guidance of doctor 

Drug free from 14th February 2023

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3 hours ago, PearlsMom1979 said:

@Barry2954 thanks again.

 

It's not craving for any particular food. It's the constant urge to keep on eating. If she asks for chocolates and I tell her chocolate is finished, do you want some nuts, she will eat nuts without any fuss.

 

She demands non stop but in the situation when her food of choice is not available, she will agree to any alternative offered.

 

This is the way I am still trying to give her healthy replacements, thanking God for small favours...

 

Urges for some particular type of food during withdrawal, I do understand that. 

 

But it's not possible to feel hungry all the time. I really don't know what is happening here in our case , if this is a withdrawal symptom or she actually needs it.

 

Anyways cannot help it much, just waiting it to pass. And praying for you and all of us here 💕  ❤️ 

Ghrelin is the substance which tells us when we are full and don't need to eat. Certain types of bacteria in our microbiomes are responsible for triggering the release of it. A hypothesis I have had about the psych meds in general, which I haven't been able to find a way to prove, has been that they disrupt our microbiomes so inducing many of our symptoms. It's possible that this is what happened with your daughter and that she no longer has healthy levels of the bacteria which trigger it's release. https://my.clevelandclinic.org/health/body/22804-ghrelin I have had to deal with this myself in switching from the sugar rich diet the benzo's caused me to eat to a much more healthy diet. Things which helped me were oils, herbs and spices, and natural prebiotics. Here is a list of the ingredients of foods I used or hope to use whether for antibacterial properties, antibiofilm properties, anti-inflammatory, or prebiotic purposes. You will need to look them up yourself to find out what they are in which your daughter eats. Palmitoleic acid, tridecanoic acid, linoleic acid, myristic acid, oleic acid, eicosapentaenoic acid, gamma-linolenic acid, polyphenols, vitamin D, fructo-oligosaccharides, inulin-oligosaccharides, pectins, beta glucans, resistant starch, fibre, omega 3, quercetin glycosides, resveratrol, vitamin B6, retinoic acid (produced in our bodies from vitamin A), curcumin, vitamin C, flavan-3-ols, gingerols, fukoidan, oleuropein, flavonol glycosides, arabinogalactans, xylanoligosaccharides, low salt diet (as this disrupts the microbiome), cinnamic acid. Sorry if that was a very technical list but apparently we are healthier if we have a wide range of bacteria in our microbiomes, including some pathogenic bacteria, rather than having it weighted towards specific bacteria and each of the prebiotics has the purpose of feeding that range of bacteria. The fatty acids/oils, as well as some other ingredients, helps with breaking down the biofilms which bacteria use to protect themselves.

 

A cheat method is to add as much palmitoylethanolamide to her diet as possible. Palmitoylethanolamide is in some foods and supplements but is also produced by healthy bacteria as it not only kills off bad bacteria but also feeds good one's. You're better off looking up the food sources for it yourself as the best sites are commercial one's which I can't provide you with a link for here.

Prior medications;

sertraline 50mg April

sertraline 100mg May to July 2014 (ceased medication immediately upon occurrence of first thunderclap headache)

lorazepam April 2014 and November 2014 to January 2015 (each time suppressing symptoms of illness until two weeks after cessation of medication)

seroquel November 2014 to January 2015 50mg prior to being raised to 100mg for one day (medication ceased immediately upon occurrence of convulsive seizure)

warfarin 1990 to June 2023

Was instructed to 'cease doing anything healthy' by treating psychiatrist in June 2014 (the psychiatrist stating that belief in disease is the cause of disease and that dietary supplementation encourages people to think there's something wrong with us) so only commenced taking supplements again in June 2023 upon contrary instructions from GP.

 

Current medications;

eliquis since June 2023

Supplements; multivitamin/mineral, zinc, magnesium, calcium/magnesium, vitamin c, vitamin d, spirulina, resveratrol, iron.

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@Barry2954 it's wonderful you know so much about these things, really impressive 😄 

 

I have gone through some of the information shared by you and I think once again you are correct. It is due to the drugs and now withdrawal only.

 

I will do more research on foods which can help her to have healthy gut microbes,thank you so much again..

 

Prayers and blessings for you and all of us here 💕 

Fluxonine April 2021 to June 2021 

Lenzo 0.5 added in June 2021

Risperidone added in July 2021

Started with 0.5 ml risperidone, dose was increased by doctor upto 4 ml till we reached November 2021

Started tapering from January 2022 and completed taper in February 2023 with the guidance of doctor 

Drug free from 14th February 2023

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Update for self records:

 

Another wave full of anger from 2nd October 

 

Overall notes of symptoms:

 

Zombie or glazed look - gone

Sitting at one place full day - gone

Mute/non verbal - gone and communication good when in windows 

Dry mouth - gone

Restlessness / akathisia - gone 

 

Cognition decline/brain fog - almost gone

Insomnia - happens sometimes 

 

Anger/rage - still present very much and whenever it comes, it's the same intensity 

 

From July till now , waves are coming in more frequency.

 

Gloria's mom had also reported something similar , from 15 month to 20 month from zero drug there was a bad period for them.

 

We are in month 19 and suffering a lot from 17th month a lot. So hoping for it to end very soon for us as well.

 

God save us.

 

Love and blessings for all of us here ❣️ 

 

 

 

 

Fluxonine April 2021 to June 2021 

Lenzo 0.5 added in June 2021

Risperidone added in July 2021

Started with 0.5 ml risperidone, dose was increased by doctor upto 4 ml till we reached November 2021

Started tapering from January 2022 and completed taper in February 2023 with the guidance of doctor 

Drug free from 14th February 2023

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This increase in anger seems to have another component which I forgot to add in above update, that is senseless increase in appetite.

 

I don't know what is causing what but she eats multiple times more than her normal diet when this anger wave comes. 

 

And if we try to stop her from overeating so much of junk, it causes more anger.

 

Fluxonine April 2021 to June 2021 

Lenzo 0.5 added in June 2021

Risperidone added in July 2021

Started with 0.5 ml risperidone, dose was increased by doctor upto 4 ml till we reached November 2021

Started tapering from January 2022 and completed taper in February 2023 with the guidance of doctor 

Drug free from 14th February 2023

Link to comment

Another thing to add: 

 

Cog fog and confusion/not able to understand anything happening around her has gone completely.

 

She knows very well what is happening around day to day.

 

In rage waves also she does know what is happening.

 

For example from the waves of last 2 times , rage is associated with over eating. So I hide all the stuff which I feel is heavy or junk or can make her unwell.

 

She is able to find and discover it all no matter where I hide it.

 

In the past she was not aware of anything, even if it was kept right under her nose. Now she observes clearly and is able to search at the right place and gets it when she thinks I am not watching. 

 

I am trying to keep an eye on her all the time but it seems now she is also keeping an eye on me.

 

Although this is good progress but it has certainly made life more difficult in one way for us.

 

She is getting her brain back nicely but she is not putting it in the right direction.

 

Telling her anything invites more anger, so I am still not forcing her, unless it's absolutely necessary to stop her.

 

Fluxonine April 2021 to June 2021 

Lenzo 0.5 added in June 2021

Risperidone added in July 2021

Started with 0.5 ml risperidone, dose was increased by doctor upto 4 ml till we reached November 2021

Started tapering from January 2022 and completed taper in February 2023 with the guidance of doctor 

Drug free from 14th February 2023

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Please if anyone can advise on this point:

 

Since Pearl's confusion is better now, she should be trying to do her activities more. But it's the opposite. Unfortunately from the month of May when she went to school for one week, then we went for holidays sometime this year, July onwards we are in continuous waves. 

And her predominant symptom is rage, so we are not mentioning anything which she does not want to do.

 

But her father feels that she is sufficiently conscious and clear of mind now and is making wrong choices.

 

I do observe that now she has a stubbornness look all the time. But I still feel we should not push her.

 

From July onwards her waves are mostly of screaming , trying to hit me and breaking stuff. And these are coming in more frequency. So there is no time for me to work out to put her in right direction.

But I also feel stubbornness is increasing month after month.

 

What should we do? These days we are almost scared of her and waiting for wave to pass, although I am again feeling it will never end :(

 

Fluxonine April 2021 to June 2021 

Lenzo 0.5 added in June 2021

Risperidone added in July 2021

Started with 0.5 ml risperidone, dose was increased by doctor upto 4 ml till we reached November 2021

Started tapering from January 2022 and completed taper in February 2023 with the guidance of doctor 

Drug free from 14th February 2023

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3 hours ago, PearlsMom1979 said:

Please if anyone can advise on this point:

 

Since Pearl's confusion is better now, she should be trying to do her activities more. But it's the opposite. Unfortunately from the month of May when she went to school for one week, then we went for holidays sometime this year, July onwards we are in continuous waves. 

And her predominant symptom is rage, so we are not mentioning anything which she does not want to do.

 

But her father feels that she is sufficiently conscious and clear of mind now and is making wrong choices.

 

I do observe that now she has a stubbornness look all the time. But I still feel we should not push her.

 

From July onwards her waves are mostly of screaming , trying to hit me and breaking stuff. And these are coming in more frequency. So there is no time for me to work out to put her in right direction.

But I also feel stubbornness is increasing month after month.

 

What should we do? These days we are almost scared of her and waiting for wave to pass, although I am again feeling it will never end :(

 

Even now, after all of these years, frustration is my trigger for the rage to return. Last week I spent a number of hours trying to get past one of those AI answering services which a company uses to try get it to let me talk to someone at the call centre. It just wouldn't let me get through. The frustration triggered my rage and I eventually gave up rather than keep fueling the rage. I discuss the similarity of this to the rages which autistic people experience, as her daughter is autistic. People assume that, because I'm intelligent enough to understand much of the science involved in benzo withdrawal and other health issues, I will be smart enough to understand pretty much anything again but it's not like that. I really have to focus to understand the research and I find myself on a single track without being able to understand a lot of other things like I could before the benzo withdrawal. Trying to force myself to understand things outside my immediate focus triggers the rages because the frustration cuts in, when no matter what I try fails. My brother has a way of trying to push me to understand things again, probably similar to how teachers would berate their students for not comprehending what they are being taught, and he has never failed to trigger my rages when he has tried this. Have you tried asking your daughter whether it is harder for her to comprehend things now? Someone on the benzo withdrawal forum put it that benzo's make us dumb. At my worst I would attempt to count to ten using my fingers and it would only take four fingers before I reached ten. I knew that I had skipped numbers but had no clue what they could have been. I'm a long way on the journey to recovery but still find it difficult to learn new things. Another thing is how is her memory? People assume that, because I have been able to remember a wide range of things, my memory must be good. However I really have to focus if I want to remember something, repeatedly researching it so that it sticks. Quite often, even after doing this, I still can't remember it (particularly if a length of time has passed). Withdrawal can induce so many potential deficits like these that I can't tell you what could be frustrating your daughter but, whatever it is, it's likely to be triggering her frustration and rage.

Prior medications;

sertraline 50mg April

sertraline 100mg May to July 2014 (ceased medication immediately upon occurrence of first thunderclap headache)

lorazepam April 2014 and November 2014 to January 2015 (each time suppressing symptoms of illness until two weeks after cessation of medication)

seroquel November 2014 to January 2015 50mg prior to being raised to 100mg for one day (medication ceased immediately upon occurrence of convulsive seizure)

warfarin 1990 to June 2023

Was instructed to 'cease doing anything healthy' by treating psychiatrist in June 2014 (the psychiatrist stating that belief in disease is the cause of disease and that dietary supplementation encourages people to think there's something wrong with us) so only commenced taking supplements again in June 2023 upon contrary instructions from GP.

 

Current medications;

eliquis since June 2023

Supplements; multivitamin/mineral, zinc, magnesium, calcium/magnesium, vitamin c, vitamin d, spirulina, resveratrol, iron.

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Oh and it's worth remembering that she, like many of us, have been victims of psychiatric treatment; traumatised by the effects of the treatment and also by many of the things which psychiatrists have told us during that treatment. An RDNS nurse, who worked as one of my support workers for a while, was of the opinion that only one of the psychiatrists at the local mental health facility, which caused my withdrawal and other related issues, was sane. She had to meet with them regarding some of their outpatients (not myself) and couldn't believe some of the things they said during their board meetings. So if they can't talk sanely at those meetings then they're definitely not going to speak sanely with patients when we are alone with them. I don't know whether I will ever recover from many of the things which the various psychiatrists demanded that I needed to believe; such as that this isn't the real world, there are no such things as pain, disease, or suffering in the real world, there are no such things as people in the real world, and so on. Most of the other patients I spoke with believed that the psychiatrists should have been the patients and the patients should have been treating them. Think of what we experience, resulting from this, as a kind of post traumatic stress disorder.

Prior medications;

sertraline 50mg April

sertraline 100mg May to July 2014 (ceased medication immediately upon occurrence of first thunderclap headache)

lorazepam April 2014 and November 2014 to January 2015 (each time suppressing symptoms of illness until two weeks after cessation of medication)

seroquel November 2014 to January 2015 50mg prior to being raised to 100mg for one day (medication ceased immediately upon occurrence of convulsive seizure)

warfarin 1990 to June 2023

Was instructed to 'cease doing anything healthy' by treating psychiatrist in June 2014 (the psychiatrist stating that belief in disease is the cause of disease and that dietary supplementation encourages people to think there's something wrong with us) so only commenced taking supplements again in June 2023 upon contrary instructions from GP.

 

Current medications;

eliquis since June 2023

Supplements; multivitamin/mineral, zinc, magnesium, calcium/magnesium, vitamin c, vitamin d, spirulina, resveratrol, iron.

Link to comment

Thank you @Barry2954

 

The main trigger is always trying to stop her, whatever she is doing. If we leave her alone , most of the time she is fine

In waves she does not get up and use the washroom, clean up , brushing etc goes for a toss. There are days when she continues to sleep for 14 hours. If we try to wake her up, it causes a huge episode of rage.

 

Today we told her to brush her teeth before breakfast, resulting in screaming and breaking stuff near her.

 

Sometimes she will say she wants to go out. We get ready in 5 mins and ask her let's go as you wanted to go, she would start screaming and won't even tell why she does not want to go out anymore. 

 

In windows she will do whatever she is told.

 

Another trigger is when we try to stop her from over eating junk.

 

Sometimes she is sitting quietly and suddenly will scream or try to hit the person sitting close to her , mostly me. In those instances, I have no clue what is happening in her mind causing the trigger.

 

 

Fluxonine April 2021 to June 2021 

Lenzo 0.5 added in June 2021

Risperidone added in July 2021

Started with 0.5 ml risperidone, dose was increased by doctor upto 4 ml till we reached November 2021

Started tapering from January 2022 and completed taper in February 2023 with the guidance of doctor 

Drug free from 14th February 2023

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1 hour ago, PearlsMom1979 said:

Thank you @Barry2954

 

The main trigger is always trying to stop her, whatever she is doing. If we leave her alone , most of the time she is fine

In waves she does not get up and use the washroom, clean up , brushing etc goes for a toss. There are days when she continues to sleep for 14 hours. If we try to wake her up, it causes a huge episode of rage.

 

Today we told her to brush her teeth before breakfast, resulting in screaming and breaking stuff near her.

 

Sometimes she will say she wants to go out. We get ready in 5 mins and ask her let's go as you wanted to go, she would start screaming and won't even tell why she does not want to go out anymore. 

 

In windows she will do whatever she is told.

 

Another trigger is when we try to stop her from over eating junk.

 

Sometimes she is sitting quietly and suddenly will scream or try to hit the person sitting close to her , mostly me. In those instances, I have no clue what is happening in her mind causing the trigger.

 

 

As I have said before; I don't know what type of withdrawal she is experiencing so I'm largely commenting on symptoms of benzo withdrawal. In that we generally experience, among a huge range of other symptoms, dental and jaw pain. Although I was still able to brush my own teeth early on, despite the jaw and tooth pain, it was actually the increasing myopathy induced by withdrawal which eventually stopped me in my tracks with brushing. I lost motor coordination and was knocking out my teeth when I tried. Back when this started I was so frustrated by everything that I was always fighting against the urges to attack people and destroy things. That's despite a lifetimes experience so you can imagine how hard it is for a child. Because I am a long hauler with the withdrawal, since psychiatrists and the local health system chose to accuse me of faking my condition, rather than acknowledging and treating it, I still can't brush my teeth even more than ten years after the withdrawal commenced. Your daughter not only lacks the decades of life's experience which I had but also doesn't have the knowledge which I now have about everything. She can't explain or vocalise what she is experiencing without the risk of triggering it if she is experiencing anything like what happened to me.

 

A quick warning; I was recently reminded that everyone kept telling me off for smashing things and the only thing which I could think of to replace the destruction, without attacking people, was to self-harm. That developed into an irresistable urge to punch myself in the head whenever the states of extreme agitation came on. So, I know that it's not easy but try to be understanding of her attacks and destruction.

Prior medications;

sertraline 50mg April

sertraline 100mg May to July 2014 (ceased medication immediately upon occurrence of first thunderclap headache)

lorazepam April 2014 and November 2014 to January 2015 (each time suppressing symptoms of illness until two weeks after cessation of medication)

seroquel November 2014 to January 2015 50mg prior to being raised to 100mg for one day (medication ceased immediately upon occurrence of convulsive seizure)

warfarin 1990 to June 2023

Was instructed to 'cease doing anything healthy' by treating psychiatrist in June 2014 (the psychiatrist stating that belief in disease is the cause of disease and that dietary supplementation encourages people to think there's something wrong with us) so only commenced taking supplements again in June 2023 upon contrary instructions from GP.

 

Current medications;

eliquis since June 2023

Supplements; multivitamin/mineral, zinc, magnesium, calcium/magnesium, vitamin c, vitamin d, spirulina, resveratrol, iron.

Link to comment

Thank you again @Barry2954

 

She does not have any pain, that is for sure. No jaw or teeth pain. Only in waves she stops brushing sometimes. Whenever she does it, it's fine, comfortable brushing no pain.

 

She was given antidepressants and then due to antidepressants side effects, she was given antipsychotic along with a drug called Pacitane, which was supposed to cover side effects of antipsychotic.

 

In between lenzo was given for sleeping. This nonsense cocktail we gave for 6 months and then understood it's uselessness and started tapering. We tapered to zero from 2 ml in around 14 months.

 

We are 19 months of being zero drug.

 

Main damages in our case seems to be from antipsychotic risperidone and not benzos.

 

Thanks for your warning.

 

We are careful with her. Most of the times when she screams we let her do it. If she breaks stuff we ignore. 

 

If she tries to attack me , I leave the room.

 

If she attacks her siblings then we do stop her.

 

I will try to be more careful though.

 

Thanks again .

Fluxonine April 2021 to June 2021 

Lenzo 0.5 added in June 2021

Risperidone added in July 2021

Started with 0.5 ml risperidone, dose was increased by doctor upto 4 ml till we reached November 2021

Started tapering from January 2022 and completed taper in February 2023 with the guidance of doctor 

Drug free from 14th February 2023

Link to comment

Just remember that I blamed the antidepressant for years before finding a publication about benzodiazepine withdrawal earlier this year and recognising the precise pattern of timing and symptoms which fit with it. Just three weeks of inpatient treatment with Lorazepam was enough to induce the withdrawal in me. If you aren't aware they use it, or another benzo, to make people sleep at night and to calm the antidepressant induced bouts of akathisia. It was only in the last couple of months that I learned that treatment with the antipsychotic Seroquel induces severe aggravation of benzo withdrawal. Don't assume, like I did, that the picture is as clear as you think. If she had any inpatient treatment then this is one possibility which you should be looking at, particularly with your mention of the antipsychotic.

 

I don't suppose that the psychiatrists ever chose to warn you that antidepressants actually increase the risk of children committing suicide and that the policy used to be never to give them to children. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493620/ The following article details the especial concerns regarding wild swings early in treatment prior to the antidepressant stabilizing a persons condition. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3353604/ Anyway, as you say, it could well be antidepressant withdrawal as this article details. https://my.clevelandclinic.org/health/diseases/25218-antidepressant-discontinuation-syndrome

Prior medications;

sertraline 50mg April

sertraline 100mg May to July 2014 (ceased medication immediately upon occurrence of first thunderclap headache)

lorazepam April 2014 and November 2014 to January 2015 (each time suppressing symptoms of illness until two weeks after cessation of medication)

seroquel November 2014 to January 2015 50mg prior to being raised to 100mg for one day (medication ceased immediately upon occurrence of convulsive seizure)

warfarin 1990 to June 2023

Was instructed to 'cease doing anything healthy' by treating psychiatrist in June 2014 (the psychiatrist stating that belief in disease is the cause of disease and that dietary supplementation encourages people to think there's something wrong with us) so only commenced taking supplements again in June 2023 upon contrary instructions from GP.

 

Current medications;

eliquis since June 2023

Supplements; multivitamin/mineral, zinc, magnesium, calcium/magnesium, vitamin c, vitamin d, spirulina, resveratrol, iron.

Link to comment

@Barry2954

 

She was never in any inpatient treatment.

 

Lorazepam was prescribed but I had not given it more than 3 days. So total 3 pills of benzo she had taken.

However, she was on risperidone for almost 6 months.

 

In either case when time is the only answer in either case, does not matter which drug is making us suffer.

 

All we have to do is wait and hold on, which we are trying our best to do.

 

Till date I have not found any solution, except time. This is what everyone says here. And some symptoms have actually gone and cognition is far far better. Communication has come almost to normal.

So hopefully with time we will be out of this awful rage also.

 

People with benzo, antidepressants and antipsychotic use, all are suffering and no one can predict the end period of their sufferings. This is the worst part.

 

Thanks a ton for your support, as always. I am always reading links given by you whenever I get any questions in mind :)

 

 

 

Fluxonine April 2021 to June 2021 

Lenzo 0.5 added in June 2021

Risperidone added in July 2021

Started with 0.5 ml risperidone, dose was increased by doctor upto 4 ml till we reached November 2021

Started tapering from January 2022 and completed taper in February 2023 with the guidance of doctor 

Drug free from 14th February 2023

Link to comment

Assuming that you're right then these articles are relevant. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7552943/   Table 2 contains routine symptoms. https://psychscenehub.com/psychinsights/antipsychotic-withdrawal-syndrome-tapering/ The list in that article is much more comprehensive though still doesn't detail aggression. Those of us who do experience this seem to be such a small minority that psychiatrists and researchers generally choose to ignore us.

Prior medications;

sertraline 50mg April

sertraline 100mg May to July 2014 (ceased medication immediately upon occurrence of first thunderclap headache)

lorazepam April 2014 and November 2014 to January 2015 (each time suppressing symptoms of illness until two weeks after cessation of medication)

seroquel November 2014 to January 2015 50mg prior to being raised to 100mg for one day (medication ceased immediately upon occurrence of convulsive seizure)

warfarin 1990 to June 2023

Was instructed to 'cease doing anything healthy' by treating psychiatrist in June 2014 (the psychiatrist stating that belief in disease is the cause of disease and that dietary supplementation encourages people to think there's something wrong with us) so only commenced taking supplements again in June 2023 upon contrary instructions from GP.

 

Current medications;

eliquis since June 2023

Supplements; multivitamin/mineral, zinc, magnesium, calcium/magnesium, vitamin c, vitamin d, spirulina, resveratrol, iron.

Link to comment

Thanks @Barry2954

 

Even if I am wrong, what will it achieve now. Whatever has happened cannot be undone. The fact is that she should not have been given these drugs. 

Symptoms are changing without doing anything also. Rage is something which is torturing us and we are desperate for it to get better or even end completely.

As I said before, whether the suffering is from benzo or risperidone, it does not make it less suffering. We all are struggling here.

Fluxonine April 2021 to June 2021 

Lenzo 0.5 added in June 2021

Risperidone added in July 2021

Started with 0.5 ml risperidone, dose was increased by doctor upto 4 ml till we reached November 2021

Started tapering from January 2022 and completed taper in February 2023 with the guidance of doctor 

Drug free from 14th February 2023

Link to comment

Knowing precise causes can give you a better idea of how to try to reverse the condition. I am looking at natural TMEM16 inhibitors, like allicin in garlic, theaflavins in black tea, silibinin in milk thistle, and niacin to try to alleviate the benzo withdrawal. This could work with your daughter but I'm not certain without understanding the precise mechanisms of her withdrawal.

Prior medications;

sertraline 50mg April

sertraline 100mg May to July 2014 (ceased medication immediately upon occurrence of first thunderclap headache)

lorazepam April 2014 and November 2014 to January 2015 (each time suppressing symptoms of illness until two weeks after cessation of medication)

seroquel November 2014 to January 2015 50mg prior to being raised to 100mg for one day (medication ceased immediately upon occurrence of convulsive seizure)

warfarin 1990 to June 2023

Was instructed to 'cease doing anything healthy' by treating psychiatrist in June 2014 (the psychiatrist stating that belief in disease is the cause of disease and that dietary supplementation encourages people to think there's something wrong with us) so only commenced taking supplements again in June 2023 upon contrary instructions from GP.

 

Current medications;

eliquis since June 2023

Supplements; multivitamin/mineral, zinc, magnesium, calcium/magnesium, vitamin c, vitamin d, spirulina, resveratrol, iron.

Link to comment

Thanks @Barry2954

I got your point but it's very difficult in case of Pearl as she has taken antidepressant for around 2-3 months, antipsychotic for another 5-6 months and lorazepam a few pills.

 

All these were given not together but one after another.

 

Along with antipsychotic, she was given Pacitane also.

So all possible types of drugs were given to her for few months each. Plus we did skip the doses in between a lot.

Entire tapering consisted of skipping doses till we reached zero.

 

So I am totally clueless as to what is causing it.

 

The reason I mentioned it could be caused by risperidone was because I think antipsychotics are the most dangerous type, worse than antidepressants and benzos. But I could be wrong as well.

 

Thanks a ton for explaining it all :)

 

 

Fluxonine April 2021 to June 2021 

Lenzo 0.5 added in June 2021

Risperidone added in July 2021

Started with 0.5 ml risperidone, dose was increased by doctor upto 4 ml till we reached November 2021

Started tapering from January 2022 and completed taper in February 2023 with the guidance of doctor 

Drug free from 14th February 2023

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I’m happy to see that Pearl is gradually improving. I think anger/rage may related to the unspoken feeling inside that make us frustrated. Have you ever try to find a therapist? Being able to express ourself, talk it out in some ways, cope with it, may help relieve the internal tension. My son had tried few ones and we are making another one now. Hopefully he will like the one from a counseling center recommended by church pastor.
 

Or have you ever think about  planning a family vocation if possible? Nature beauty can really sooth us. When my son is more stable, I really want to take him go out some time to a place with beautiful water, lakes, trees and  flowers . 
 


 

 

Son: 2020-Aug: Ambience, 5 days; 2022-July:Trazodone 50mg on/off about 40 days, cold turkey off

2022-Nov: Risperidone 1mg morning, 1mg evening;  Depakote 250mg morning, 500mg evening 

        (Tried serval times to tape Risperidone to half of morning dose in year 2022, but reinstate back) 

2023-Feb 26-March 16: Taped both Risperidone and Depakote by skipping the entire morning doses

2023-March 17-March 26: Reinstate by skipping every other day of morning doses

2023-March 26-march 29: Reinstate both Risperidone and Depakote back to the original doses. 

2023-March 30-Now: Depakote 250mg twice a day(Taped 250mg evening dose)
2023-April 11-April 15:  0.5mg Risperidone in the morning and 1mg in the evening for 5 day

2023-April 16-Now: Risperidone 1mg morning, 1mg evening; 

2022: Nov-Feb 26 2023: Mirtazapine 7.5mg; 2023 Feb 27-March 26: taped Mirtazapine 7.5mg every other day for 4 weeks, 2023-March 27-April 18 : taped Mirtazapine 7.5mg twice a week (Tue , Friday)

2023-April 19-Now: 3.75mg Mirtazapine, occasionally skipped for few times due to tiredness. On 9/26/23 last year started  a 10 month tapering of 2mg Risperidone 10-15 % every two weeks.During 0.04mg for 2 weeks on July,  experiencinv hallucinations. But still, in July 16, 2024 jumpped to zero of risperidone out of concern of inaccurate small dose.  After the jumping,  Gogo has manageable small wave but generally feel very good. The changes started on 9/13 with increased disorganized behavior. So on 9/23/24 We updosed  to .25mg for a shy of week after an anger burst out of control. On 9/29/24 updose to .5mg 

 

Link to comment
7 hours ago, PearlsMom1979 said:

Thanks @Barry2954

I got your point but it's very difficult in case of Pearl as she has taken antidepressant for around 2-3 months, antipsychotic for another 5-6 months and lorazepam a few pills.

 

All these were given not together but one after another.

 

Along with antipsychotic, she was given Pacitane also.

So all possible types of drugs were given to her for few months each. Plus we did skip the doses in between a lot.

Entire tapering consisted of skipping doses till we reached zero.

 

So I am totally clueless as to what is causing it.

 

The reason I mentioned it could be caused by risperidone was because I think antipsychotics are the most dangerous type, worse than antidepressants and benzos. But I could be wrong as well.

 

Thanks a ton for explaining it all :)

 

 

I think that you can be reasonably certain that the Pacitane wasn't responsible. While there don't seem to be many articles on antispasmodic withdrawal this one on Baclofen withdrawal seems to paint a different picture from that which you have described. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5167087/ However I had the thought to check something and it turns out that one of the effects of excess ghrelin levels is aggression. https://www.sciencedirect.com/science/article/pii/S0306453018311752   So your daughters constant hunger, resulting from high ghrelin levels, is likely triggering her rages. Here is a page on ghrelin and its effects on hunger. https://my.clevelandclinic.org/health/body/22804-ghrelin  She is likely to be going through waves of satiation of the hunger followed by increases in ghrelin triggering her to overeat. With the exception of that one all of the pages on how to reduce ghrelin production by the body seem to be commercial one's which I can't provide you with links for here.

Prior medications;

sertraline 50mg April

sertraline 100mg May to July 2014 (ceased medication immediately upon occurrence of first thunderclap headache)

lorazepam April 2014 and November 2014 to January 2015 (each time suppressing symptoms of illness until two weeks after cessation of medication)

seroquel November 2014 to January 2015 50mg prior to being raised to 100mg for one day (medication ceased immediately upon occurrence of convulsive seizure)

warfarin 1990 to June 2023

Was instructed to 'cease doing anything healthy' by treating psychiatrist in June 2014 (the psychiatrist stating that belief in disease is the cause of disease and that dietary supplementation encourages people to think there's something wrong with us) so only commenced taking supplements again in June 2023 upon contrary instructions from GP.

 

Current medications;

eliquis since June 2023

Supplements; multivitamin/mineral, zinc, magnesium, calcium/magnesium, vitamin c, vitamin d, spirulina, resveratrol, iron.

Link to comment

Further to my last, I was looking at factors involved in my own withdrawal and found this article, mentioning benzodiazepine inhibition of adenosine transport. https://pubmed.ncbi.nlm.nih.gov/2866831/   Following up on that I found out that adenosine plays a role in regulating ghrelin release. https://jpet.aspetjournals.org/content/336/1/77.short  Thinking of your daughter I looked up the various medications to see whether any had a relationship with adenosine. It turns out that Fluoxetine does, assuming that you mistyped that when you put down Fluxonine. https://www.sciencedirect.com/science/article/abs/pii/S104366180500157X It's only a guess but that would be my best bet about the trigger for her current symptoms.

Prior medications;

sertraline 50mg April

sertraline 100mg May to July 2014 (ceased medication immediately upon occurrence of first thunderclap headache)

lorazepam April 2014 and November 2014 to January 2015 (each time suppressing symptoms of illness until two weeks after cessation of medication)

seroquel November 2014 to January 2015 50mg prior to being raised to 100mg for one day (medication ceased immediately upon occurrence of convulsive seizure)

warfarin 1990 to June 2023

Was instructed to 'cease doing anything healthy' by treating psychiatrist in June 2014 (the psychiatrist stating that belief in disease is the cause of disease and that dietary supplementation encourages people to think there's something wrong with us) so only commenced taking supplements again in June 2023 upon contrary instructions from GP.

 

Current medications;

eliquis since June 2023

Supplements; multivitamin/mineral, zinc, magnesium, calcium/magnesium, vitamin c, vitamin d, spirulina, resveratrol, iron.

Link to comment

Thank you @Dshine for your kind words and it's nice to know that Gogo is getting better.

 

We did go to a vacation few months back.

 

From July onwards we are facing nasty waves back to back, so not getting much breathing time.

 

We will consider counselling once we find she is receptive enough. So far counselling has proved a wastage of time only.

 

Sending you love and blessings 💕 💕 

Fluxonine April 2021 to June 2021 

Lenzo 0.5 added in June 2021

Risperidone added in July 2021

Started with 0.5 ml risperidone, dose was increased by doctor upto 4 ml till we reached November 2021

Started tapering from January 2022 and completed taper in February 2023 with the guidance of doctor 

Drug free from 14th February 2023

Link to comment

Thank you so much again @Barry2954

 

 

So it appears her gheralin in decreased causing her more appetite and more irritation? I have checked foods providing this and so far the only food which has gheralin and which Pearl likes is Peanuts. I will try to find more and include it in her diet.

 

Also as to your second message, yes I misspelt it , I meant Fluoxetine only.

 

It's wonderful that you know so much and thank you again for doing so much research and helping us out. I am reading all the links and try to find useful points which I can implement practically to survive this phase.

 

Thanks a lot again , God bless you 💖 

Fluxonine April 2021 to June 2021 

Lenzo 0.5 added in June 2021

Risperidone added in July 2021

Started with 0.5 ml risperidone, dose was increased by doctor upto 4 ml till we reached November 2021

Started tapering from January 2022 and completed taper in February 2023 with the guidance of doctor 

Drug free from 14th February 2023

Link to comment

Again, you're welcome. This isn't completely selfless though as I find that helping others also helps me and I've learnt that the Zoloft I was on was likely partially responsible for my own withdrawal aggression by exacerbating iron deficiency. I don't actually know much other than how to search for the right words to find answers in medical research as well as knowing when I am looking at rubbish research. Yes, it appears as though low levels of ghrelin not only trigger excessive eating but also aggression. https://www.nature.com/articles/ijo2017123    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4343161/ This is an excerpt from the second article; "we now find that circulating BChE has a large impact on aggressive behavior in mice that is attributable to its ability to inactivate ghrelin, a peptide hormone involved in hunger, feeding, and stress. A key observation was decreased fighting among group-housed male mice overexpressing BChE after viral gene transfer. In contrast, BChE knockout mice exhibited increased fighting." The BChE detailed in the article is an enzyme which breaks down acetylcholine, so lowers depression, as well as seemingly playing some role in ghrelin production.

 

The aggression is likely an expression of the damage to the body which occurs when those levels are low. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581611/ I don't yet know whether iron plays a role in raising levels of BChE but the enzyme is definitely iron-dependent. https://www.mdpi.com/1422-0067/22/4/2033    So low levels of iron absorption will exacerbate your daughters condition. That means that my previous advice about Fluoxetine being the potential cause of her condition was wrong. It doesn't induce iron deficiency but Risperidone does. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6728911/  So you were right to think that Risperidone was the cause of her condition. This means that it may be possible to gradually raise her iron levels in order to normalise her behaviour. That's likely to support the other persons suggestion that periods likely influence the bouts of aggression. Don't go straight to very high doses of iron as that will likely just result in high levels of oxidative stress. People with lots of iron in their diets tend to age very quickly because of that. https://www.sciencedirect.com/science/article/pii/S016748891930148X My advice is to shift her diet to these kinds of foods rather than giving her supplements. https://www.medicinenet.com/how_can_i_raise_my_iron_levels_fast/article.htm That article also details the necessity of increasing vitamin C intake, which increases iron absorption.

Prior medications;

sertraline 50mg April

sertraline 100mg May to July 2014 (ceased medication immediately upon occurrence of first thunderclap headache)

lorazepam April 2014 and November 2014 to January 2015 (each time suppressing symptoms of illness until two weeks after cessation of medication)

seroquel November 2014 to January 2015 50mg prior to being raised to 100mg for one day (medication ceased immediately upon occurrence of convulsive seizure)

warfarin 1990 to June 2023

Was instructed to 'cease doing anything healthy' by treating psychiatrist in June 2014 (the psychiatrist stating that belief in disease is the cause of disease and that dietary supplementation encourages people to think there's something wrong with us) so only commenced taking supplements again in June 2023 upon contrary instructions from GP.

 

Current medications;

eliquis since June 2023

Supplements; multivitamin/mineral, zinc, magnesium, calcium/magnesium, vitamin c, vitamin d, spirulina, resveratrol, iron.

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Thank you so much @Barry2954

 

It's insightful and interesting information.

 

Sure I will try to give her diet with little more iron and vitamin C content.

 

So far we have not given her any supplements.

 

We have tried giving her Bach flower and homoeopathic medicine for anger but nothing seems to be helping.

 

This time also the wave is bad and going on really long.

 

Blessings and prayers for you and all of us 💟 💟 

Fluxonine April 2021 to June 2021 

Lenzo 0.5 added in June 2021

Risperidone added in July 2021

Started with 0.5 ml risperidone, dose was increased by doctor upto 4 ml till we reached November 2021

Started tapering from January 2022 and completed taper in February 2023 with the guidance of doctor 

Drug free from 14th February 2023

Link to comment

Update:

 

Wave which started somewhere in September, probably 27th September, is finally over on 9th October.

 

Almost 2 weeks of hell, full of anger, rage, screaming, breaking stuff, hitting me , not using washroom , no drinking water, finally ended.

 

Now full silence, sitting in peace and watching tv.

 

Let's see what happens next.

 

Rage is the only symptom remaining.

 

Love and blessings to all of us here 💕

Fluxonine April 2021 to June 2021 

Lenzo 0.5 added in June 2021

Risperidone added in July 2021

Started with 0.5 ml risperidone, dose was increased by doctor upto 4 ml till we reached November 2021

Started tapering from January 2022 and completed taper in February 2023 with the guidance of doctor 

Drug free from 14th February 2023

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  • 2 weeks later...

Hello!
I just wanted to say that you are very good for being close to your child and trying to find ways to help your daughter. Our children's diseases are thousands of times worse than our own, I understand you. It's terrible, and it should be forbidden to give such pills to children.

2019-2020 fluoxetine due to anxiety disorder (1 capsule per day), withdrawal without WD.

2021- 1 month of Atarax in a daily dosage of 25 mg + symptomatically for a year 1/4 of 25 mg (approximately once a month).

2023 - severe stress, Atarax symptomatically 1/2 of 25 mg (approximately once a month / once a week). Velaxine (min. dosage 1 day) pronounced side effect in the form of an uncontrolled panic attack, withdrawal.

February 2024 - Zoloft (+ Atarax 1.5 months in a dosage of 1/2 25 mg to 50 mg at a time almost every day) with a gradual increase once a week to 75 mg, constant headache, tremor, anxiety, poor eyesight. Then reduce the dose for 3 weeks to 0 mg.

April 2024 - On the 10th day after complete abstinence, derealization, depression, panic attacks, headache, blurred vision, fog in the head, delirium. April 2024 - about once every three days, Atarax 25 mg, slightly relieved the symptoms, then I did not understand what was wrong with me.


MY PROGRESS: https://docs.google.com/spreadsheets/d/1FeyWn2cUXt8UGRp0th2-hMbfjJBzb2PU6Xyg2HcKy_4/edit

 

MY SYMPTOMS: derealization +; wave extreme depression + ; nausea +/- ; loss of appetite +/- ;

 insomnia; weakness in the hands; panic attacks; paresthesia; anxiety; blurred vision; pictures before going to bed; morning cortisol awakenings

 

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Pearlsmom, thinking about you. Hope Pearl is getting better! 
 

❤️❤️❤️

Son: 2020-Aug: Ambience, 5 days; 2022-July:Trazodone 50mg on/off about 40 days, cold turkey off

2022-Nov: Risperidone 1mg morning, 1mg evening;  Depakote 250mg morning, 500mg evening 

        (Tried serval times to tape Risperidone to half of morning dose in year 2022, but reinstate back) 

2023-Feb 26-March 16: Taped both Risperidone and Depakote by skipping the entire morning doses

2023-March 17-March 26: Reinstate by skipping every other day of morning doses

2023-March 26-march 29: Reinstate both Risperidone and Depakote back to the original doses. 

2023-March 30-Now: Depakote 250mg twice a day(Taped 250mg evening dose)
2023-April 11-April 15:  0.5mg Risperidone in the morning and 1mg in the evening for 5 day

2023-April 16-Now: Risperidone 1mg morning, 1mg evening; 

2022: Nov-Feb 26 2023: Mirtazapine 7.5mg; 2023 Feb 27-March 26: taped Mirtazapine 7.5mg every other day for 4 weeks, 2023-March 27-April 18 : taped Mirtazapine 7.5mg twice a week (Tue , Friday)

2023-April 19-Now: 3.75mg Mirtazapine, occasionally skipped for few times due to tiredness. On 9/26/23 last year started  a 10 month tapering of 2mg Risperidone 10-15 % every two weeks.During 0.04mg for 2 weeks on July,  experiencinv hallucinations. But still, in July 16, 2024 jumpped to zero of risperidone out of concern of inaccurate small dose.  After the jumping,  Gogo has manageable small wave but generally feel very good. The changes started on 9/13 with increased disorganized behavior. So on 9/23/24 We updosed  to .25mg for a shy of week after an anger burst out of control. On 9/29/24 updose to .5mg 

 

Link to comment

Hey PearlsMom, you're really brave and I wish for you this fight is over soon..

 

What Barry2954 mentioned about iron absorption is super insightful and I think a really good clue in your case! I remember my father-in-law, who started having aweful bouts of verbal aggression after a sickness, was taking iron supplements. I understand Pearl is young, but usually GPs can comment on finding a natural supplement that is suitable for her.

 

Foods I know that are rich in iron, are all kinds of liver products and leafy greens. I know some traditional cuisines don't use the internal organs of the animals at all, but the liver is a treasury of micro-elements, so I really recommend it! Personally I try to have some pate or Leberwurst around my period as it boosts my energy. Barry's research helps me realise that it might be helping stabilise my mood, too (as I also spent some time on Risperidone, even though it's long ago already). :)

In the end of 2015, got into a few days of psychosis and got an outpatient appointment with a psychiatrist, a diagnosis of schizo-affective disorder and a 2 month treatment with Risperidone. At the current point in time, my doctor is not convinced anymore in the diagnosis, rather points out depression and anxiety as my main condition, but I'm still taking Abilify as prevention therapy.

  • 2016 - 7.5 mg Abilify; 2017 - 2018 - 2 mg; April 2019 - May 2020 - 5 mg; June - December 2020 - 4.5 - 2.3 mg (-10% / month)

-> early 2021 - upped a little bit because of a depressive episode and insomnia

  • March 2021 to Jan 2022 - down to 0.7 mg

-> Feb 2023 - another depression+insomnia episode, so up again; added vit. B3, melatonin, L-tryptophan and split the Abilify dose in two

  • May 2022 to Nov 2022 - 2 mg down to 0.75 mg

-> middle of January 2023 - insomnia kicked in, some derealizations too; so up to:

  • Jan-April - 1 mg Abilify up to 1.5 mg; added Quetiapin 6 mg for a month, then down to 0 mg
  • 2024: dropped gradually Abilify to 0.5 mg and further down to 0.3 mg

Current: 0 mg Abilify since 8th of July 🥳 Holding the situation with aminoacids (tyrosine, tryptophan), Omega-3, Gingko biloba, occasional magnesium, calming herbs and CBD. Getting agitated, 2-3 nights of reduced sleep or depressed at certain phases of my period, overall improved mood and motivation is coming back. Appetite has reduced dramatically, weight is also slowly going down and energy levels - up. I can sweat again!

Link to comment
24 minutes ago, Nocturna said:

Hey PearlsMom, you're really brave and I wish for you this fight is over soon..

 

What Barry2954 mentioned about iron absorption is super insightful and I think a really good clue in your case! I remember my father-in-law, who started having aweful bouts of verbal aggression after a sickness, was taking iron supplements. I understand Pearl is young, but usually GPs can comment on finding a natural supplement that is suitable for her.

 

Foods I know that are rich in iron, are all kinds of liver products and leafy greens. I know some traditional cuisines don't use the internal organs of the animals at all, but the liver is a treasury of micro-elements, so I really recommend it! Personally I try to have some pate or Leberwurst around my period as it boosts my energy. Barry's research helps me realise that it might be helping stabilise my mood, too (as I also spent some time on Risperidone, even though it's long ago already). :)

Just be careful with amounts of iron. There is a complex interrelationship between iron and how our brain functions. High levels cause their own set of symptoms just as bad as low levels. https://pmc.ncbi.nlm.nih.gov/articles/PMC6789770/

Prior medications;

sertraline 50mg April

sertraline 100mg May to July 2014 (ceased medication immediately upon occurrence of first thunderclap headache)

lorazepam April 2014 and November 2014 to January 2015 (each time suppressing symptoms of illness until two weeks after cessation of medication)

seroquel November 2014 to January 2015 50mg prior to being raised to 100mg for one day (medication ceased immediately upon occurrence of convulsive seizure)

warfarin 1990 to June 2023

Was instructed to 'cease doing anything healthy' by treating psychiatrist in June 2014 (the psychiatrist stating that belief in disease is the cause of disease and that dietary supplementation encourages people to think there's something wrong with us) so only commenced taking supplements again in June 2023 upon contrary instructions from GP.

 

Current medications;

eliquis since June 2023

Supplements; multivitamin/mineral, zinc, magnesium, calcium/magnesium, vitamin c, vitamin d, spirulina, resveratrol, iron.

Link to comment

@didiyana

@Dshine

@Nocturna

@Barry2954

 

Thank you so much for stopping by and asking about Pearl.

 

After that wave of rage which ended on 9th October, there was a nice window but lasted only one week. 

During that week we went for a small trip for a change. She enjoyed that trip.

 

After that trip on 15th October she hit another wave. This time it was not rage. It was fear and crying. Luckily it lasted only 5 days. From yesterday she is fine and another window of clarity has started. 

 

Hope you all are doing good.

 

Nocturna your comments on iron intake and ofcourse awesome reasearch by Barry is highly useful. I am trying to give her a balanced diet always. Sometimes she tends to overeat esp junk food and it becomes tough to control but mostly it's balanced food only.

 

Didiyana yes I completely agree. It should be a punishable crime , prescribing these medicines, to anyone and especially to kids. But what can we do, the big pharma lobby is more powerful than the government.

 

Dshine so sweet of you for checking on us. We are doing comparatively better. How are you and how is your son doing now? 

 

Lots of love and blessings to you all and our other friends here 💞 💞 

Fluxonine April 2021 to June 2021 

Lenzo 0.5 added in June 2021

Risperidone added in July 2021

Started with 0.5 ml risperidone, dose was increased by doctor upto 4 ml till we reached November 2021

Started tapering from January 2022 and completed taper in February 2023 with the guidance of doctor 

Drug free from 14th February 2023

Link to comment

I'm glad to hear that things seem to be improving. The information isn't directly relevant to your daughter but I recently found in medical research the most likely source of my own withdrawal rage and it was actually only partially the benzodiazepines. I detail this to help you to understand just how complex the interactions between medications can be. It turned out that SSRI antdepressants actually act through serotonin receptors, particularly a type called 5-HT1A. When treatment with antidepressants is ceased there is a set of these receptors in the raphe nucei, in the reticular formation of the brainstem, which experience reduced function. These receptors inhibit rage and aggression and play roles in mood regulation, respiratory function, motor function, memory, photosensitivity, circadian rhythm, spatial awareness, sense of balance, pain sensitivity, anxiety, gastrointestinal motility, and so on. Basically the psychiatrists knocked out my brainstem function so causing all of my symptoms which were then greatly aggravated by the benzodiazepine withdrawal and knockout of GABA-A receptors which would usually reduce those symptoms. So it may be worth looking at the effects of the other medications your daughter was on in order to try to work out whether it really was as simple as the respiridone and iron deficiency. Remember that a lot of people in withdrawal also react badly to certain foods and supplements as well.

Prior medications;

sertraline 50mg April

sertraline 100mg May to July 2014 (ceased medication immediately upon occurrence of first thunderclap headache)

lorazepam April 2014 and November 2014 to January 2015 (each time suppressing symptoms of illness until two weeks after cessation of medication)

seroquel November 2014 to January 2015 50mg prior to being raised to 100mg for one day (medication ceased immediately upon occurrence of convulsive seizure)

warfarin 1990 to June 2023

Was instructed to 'cease doing anything healthy' by treating psychiatrist in June 2014 (the psychiatrist stating that belief in disease is the cause of disease and that dietary supplementation encourages people to think there's something wrong with us) so only commenced taking supplements again in June 2023 upon contrary instructions from GP.

 

Current medications;

eliquis since June 2023

Supplements; multivitamin/mineral, zinc, magnesium, calcium/magnesium, vitamin c, vitamin d, spirulina, resveratrol, iron.

Link to comment

Actually it turns out that the risperidone may act in a very similar way to SSRI medications in activation of the 5-HT1A receptors. Whether this leads to similar effects following treatment I couldn't tell you. https://pubmed.ncbi.nlm.nih.gov/31430459/ https://pmc.ncbi.nlm.nih.gov/articles/PMC5543701/

Prior medications;

sertraline 50mg April

sertraline 100mg May to July 2014 (ceased medication immediately upon occurrence of first thunderclap headache)

lorazepam April 2014 and November 2014 to January 2015 (each time suppressing symptoms of illness until two weeks after cessation of medication)

seroquel November 2014 to January 2015 50mg prior to being raised to 100mg for one day (medication ceased immediately upon occurrence of convulsive seizure)

warfarin 1990 to June 2023

Was instructed to 'cease doing anything healthy' by treating psychiatrist in June 2014 (the psychiatrist stating that belief in disease is the cause of disease and that dietary supplementation encourages people to think there's something wrong with us) so only commenced taking supplements again in June 2023 upon contrary instructions from GP.

 

Current medications;

eliquis since June 2023

Supplements; multivitamin/mineral, zinc, magnesium, calcium/magnesium, vitamin c, vitamin d, spirulina, resveratrol, iron.

Link to comment

Thank you so much Barry

I will go through the information provided by you.

 

 

Pearl is doing fine on emotional issues.

 

Her digestion problem (diarrhea) is back.

 

Hopefully it will settle soon.

 

Overall she is much better.

 

 

Love and blessings ❤️ ❤️ 💗 

Fluxonine April 2021 to June 2021 

Lenzo 0.5 added in June 2021

Risperidone added in July 2021

Started with 0.5 ml risperidone, dose was increased by doctor upto 4 ml till we reached November 2021

Started tapering from January 2022 and completed taper in February 2023 with the guidance of doctor 

Drug free from 14th February 2023

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