PurpleRein: Have you heard about MTHFR mutations?

[PurpleRein]

Hi everyone,

I lost my son to suicide a few days after his dose of Zoloft was increased.  So I've been researching for the past 3 years.  I don't mean just reading a few studies.  I mean all the time.

 

Anyway, the other day I visited one of the Facebook groups and I noticed something very interesting.  The "withdrawal symptoms" you guys are having are the exact same symptoms caused by MTHFR mutations, which makes sense since both antidepressants and MTHFR mutations cause the same vitamin deficiencies.  Please allow me to explain.  

The MTHFR gene helps absorb Folic Acid.  You need Folic Acid and Vitamin B12 to be able to recycle homocysteine (which is toxic to neurons) into something useful (Methionine) to be able to make SAM-e which is needed to make brain neurotransmitters and hormones, and many other important processes.

 

When you have MTHFR mutations (variations), they decrease your ability to absorb Folic Acid so it disrupts the entire cycle and that can cause low Folate, low Vitamin B12, low Vitamin D and high homocysteine, which can cause many symptoms...like all the ones you guys are having.....brain fog, brain zaps, neuropathy, paresthesias, akithesia, gastroparesis, gait disturbance, anxiety, erectile dysfunction, orthostatic tachycardia, sleep problems, chronic fatigue syndrome, joints pain and aches, eye problems, and much more.  They are also associated with anxiety, depression, autism, ADHD, Bipolar disorder and schizophrenia.  

 

MTHFR also helps detoxify, so when you have mutations, that decreases your ability to detoxify and metal levels can get too high.  That may cause you to have reactions to chemicals, additives, and even some supplements..

 

Antidepressants and antipsychotics cause deficiencies of the same vitamins.  Look, this is from the NIH.  It's a list of meds that cause vitamin deficiencies.  Look at the part that says SSRI's.  It tells you which vitamins it affects and under Risk factors it lists MTHFR mutations. 

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874849/

 

I realize that you don't know me and you might not believe me but I would feel guilty if I didn't tell you because mutations can be treated by doctors who have experience doing so.  Please let me know if you need more sources.

[Altostrata]

Hello, @PurpleRein

 

I am sorry you lost your son.

 

Yes, we know about MTHFR mutations. Most are normal mutations. In general, they have no bearing on withdrawal symptoms.

 

Many conditions have symptoms similar to withdrawal symptoms. Similarity in symptoms does not mean much.

 

FYI