FernanCC Posted August 25, 2023 Posted August 25, 2023 Hi all, On 08/2023 I am a 25 year old male, soon to be 26. I have used a SSRI called "sertraline" for over five (05) years, I ended the SSRIs daily 100mg "treatment" on 18th of July 2023, due to changes in my environment, this allowed me to move from a stressing environment to a healthier one. Being a month "clean", I am developing back my "nervous system excitement". I feel more active and awake, on that note I am also finding trouble sleeping, additionally my sex drive and full genitalia sensibility have came back, The secondary effect that I am still experiencing is weight gain, It has been progressive and it seems to have been consolidating too, because my metabolism seems to have completely changed; * A lot of foods are now aggressive to my gut causing heartburn and intestinal gas => I have woken in the middle of the night to throw up due to the acidic response in my stomach. * I have had diabetic episodes, of not being able to stop peeing and feeling dizzy * Most importantly, seemingly effective and well-executed diets are miserably failing, and I went from having a privileged metabolism, to feeling like anything makes me fat. My perception is that years of SSRIs use have caused accumulation of residual chemicals in my body, which are now altering my metabolism. I am following the thread behind this mechanism, but it seems unexplored. Lastly I joined here as last resort, hoping to hear encouraging testimonials or at least promising lines of action, thanks. * Sertraline 100mg after breakfast for 05 years - quit cold turkey no symptoms. (August 2023). * Reinstatement of sertraline, immediately get start up symptoms and withdrawal until dose adjustment in 150mg (May 2024). * Currently tapering at 75mg.
Moderator Go2zero Posted August 25, 2023 Moderator Posted August 25, 2023 Hello @FernanCC, Welcome to this support site. Before we can answer your questions, please give us more information first. Good that you came to this website. There is a lot of knowledge to be found and shared here. Also the members can support each other here. Can you please give us specific information about your drug history for all drugs you are on and have been on? Please read the link below for instructions. This will allow us to give you the best guidance. https://www.survivingantidepressants.org/topic/28240-how-to-summarize-your-drug-history-in-your-signature/ As soon as we have this signature we can advise you further. For now it seems to me that you are suffering from Withdrawal syndrome. Drugs like sertraline should be tapered of very slowly and careful. Going too fast can give extreme withdrawal symptoms. Luckily you did not stop that long ago, so probably it will be possible to stop this withdrawal process. Here is some important and interesting info you can read: 1993 Anafranil (Clomipramine) for a few months. Later in 1993 Paxil for a few months 1993- 2006 No medication 2006 Effexor, Cymbalta, some Benzo’s. All for short periods. Later in 2006 Lexapro (escitalopram) 10 mg and shortly after Wellbutrin XR 150mg, against side effects Lexapro Since 2006 until end of 2015: Several times on and off Lexapro and Wellbutrin and several slight dosage changes. Mostly taken dosages: 5mg Lexapro and 150mg Wellbutrin 2016 Dosage change Lexapro from 5mg to 2,5 mg. Wellbutrin stayed om 150mg November 2016 – April 2017 Down from 2,5mg to 0,6mg Lexapro (in steps) without much problems. Wellbutrin down from 150mg to 66mg. Also without much problems. April 2017 – March 2019 Lexapro 0,6 mg April 2017 - August 2018 Wellbutrin in small steps down from 66mg in to 37,5 mg . Quite heavy WD after each step. March 2019 – May 2019 Lexapro down from 0,6 to 0,3mg then Prozac to 0,6 mg switch because severe discontinuation effects (may also have been from Wellbutrin..) Wellbutrin down from 37,5mg to 35,3mg October 2019 Seroquel 12,5 mg for 4 weeks because of extreme sleeping problems, then weaning off in 2 weeks Prozac up dosage to 1,2 mg March 2020 Wellbutrin in 2 steps down from 35,3mg to 33,3mg Extreme withdrawal effects during 8 months. Stopped tapering Wellbutrin until total off Prozac. February 2020 – November 2020 Prozac down in steps from 1,2mg to 0,57mg. Jan 2021 : Prozac down to: 0,55> 0,53>0,51mg, Feb 0,47mg , Mar 0,42mg, Apr 0,37, longer hold because of WD symptoms July 0,36 and hold again, Sept 19 0,35, Sept 26 0,34mg, Oct 3 0,33mg Long hold of 172 days until March 2022 January 20, 2022: Wellbutrin from 33,3 to 32,4mg March 22, 2022 Prozac down from 0,33mg to: 0,30mg, Apr 0,29, May 0,28, 0,27, June 0,26, 0,25, July 0,24, 0,23, 0,22, 0,21, Aug 0,20, 0,19 Sep 0,18, Oct 0,17. 0,16, 0,15, Nov 0,14 Jan 2023 0,13, 0,12, 0,11 Feb 0,10, 0,09 Mar 0,08 , June 0,07 , July 0,06, 0,05, Aug 0,04, 0,03, Sept 0,026, 0,024 Nov 0,022, 0,019, 0,016, 0,013 Dec 0,012, 0,011, 0,010, 0,009 Jan 2024 0,008, 0,007, 0,006, 0,005, 0,004, 0,003, 0,002, 0,001, Feb 0,0007. 0,0005, 0,0003, 0,0001, Feb 23, 2024: 0,00000 Wellbutrin resume tapering: Apr 2024 31,6mg, 30,8, 30,0 , May 29,1, 28,2, July 23,7, Aug 22,6, 21,4, Dec 21,0, 20,5, 20,0 Jan 2025 19,6 mg Supplements: Fish Oil (3000mg), Magnesium 100 mg, 2 drops of Lavender Oil, only when feeling extreme anxiety. 50mg of L-Theanine only when severe discontinuation effects caused by Wellbutrin Please note this is NOT a medical advice. Discuss all your medical issues with a doctor who understands psychical drugs and really knows how to withdraw from them. I wish that you will find one.
FernanCC Posted August 25, 2023 Author Posted August 25, 2023 1 hour ago, Go2zero said: Hello @FernanCC, Welcome to this support site. Before we can answer your questions, please give us more information first. Good that you came to this website. There is a lot of knowledge to be found and shared here. Also the members can support each other here. Can you please give us specific information about your drug history for all drugs you are on and have been on? Please read the link below for instructions. This will allow us to give you the best guidance. https://www.survivingantidepressants.org/topic/28240-how-to-summarize-your-drug-history-in-your-signature/ As soon as we have this signature we can advise you further. For now it seems to me that you are suffering from Withdrawal syndrome. Drugs like sertraline should be tapered of very slowly and careful. Going too fast can give extreme withdrawal symptoms. Luckily you did not stop that long ago, so probably it will be possible to stop this withdrawal process. Here is some important and interesting info you can read: I just added my signature, although I had already mentioned my medication and dosage at the top of my post, My post really is not so much about withdrawal, but rather about how I have developed a diabetic profile, which is something contemplated in the literature. My concern is to not only loose weight, but to reverse the effects of the medication on my metabolism, which seem to have some sort of carry-over. Regards. * Sertraline 100mg after breakfast for 05 years - quit cold turkey no symptoms. (August 2023). * Reinstatement of sertraline, immediately get start up symptoms and withdrawal until dose adjustment in 150mg (May 2024). * Currently tapering at 75mg.
Moderator Go2zero Posted August 26, 2023 Moderator Posted August 26, 2023 (edited) Since when did you develop this diabetic profile? What are your blood sugar figures. When was this tested? And since when did you start gaining weight? Edited August 26, 2023 by Go2zero 1993 Anafranil (Clomipramine) for a few months. Later in 1993 Paxil for a few months 1993- 2006 No medication 2006 Effexor, Cymbalta, some Benzo’s. All for short periods. Later in 2006 Lexapro (escitalopram) 10 mg and shortly after Wellbutrin XR 150mg, against side effects Lexapro Since 2006 until end of 2015: Several times on and off Lexapro and Wellbutrin and several slight dosage changes. Mostly taken dosages: 5mg Lexapro and 150mg Wellbutrin 2016 Dosage change Lexapro from 5mg to 2,5 mg. Wellbutrin stayed om 150mg November 2016 – April 2017 Down from 2,5mg to 0,6mg Lexapro (in steps) without much problems. Wellbutrin down from 150mg to 66mg. Also without much problems. April 2017 – March 2019 Lexapro 0,6 mg April 2017 - August 2018 Wellbutrin in small steps down from 66mg in to 37,5 mg . Quite heavy WD after each step. March 2019 – May 2019 Lexapro down from 0,6 to 0,3mg then Prozac to 0,6 mg switch because severe discontinuation effects (may also have been from Wellbutrin..) Wellbutrin down from 37,5mg to 35,3mg October 2019 Seroquel 12,5 mg for 4 weeks because of extreme sleeping problems, then weaning off in 2 weeks Prozac up dosage to 1,2 mg March 2020 Wellbutrin in 2 steps down from 35,3mg to 33,3mg Extreme withdrawal effects during 8 months. Stopped tapering Wellbutrin until total off Prozac. February 2020 – November 2020 Prozac down in steps from 1,2mg to 0,57mg. Jan 2021 : Prozac down to: 0,55> 0,53>0,51mg, Feb 0,47mg , Mar 0,42mg, Apr 0,37, longer hold because of WD symptoms July 0,36 and hold again, Sept 19 0,35, Sept 26 0,34mg, Oct 3 0,33mg Long hold of 172 days until March 2022 January 20, 2022: Wellbutrin from 33,3 to 32,4mg March 22, 2022 Prozac down from 0,33mg to: 0,30mg, Apr 0,29, May 0,28, 0,27, June 0,26, 0,25, July 0,24, 0,23, 0,22, 0,21, Aug 0,20, 0,19 Sep 0,18, Oct 0,17. 0,16, 0,15, Nov 0,14 Jan 2023 0,13, 0,12, 0,11 Feb 0,10, 0,09 Mar 0,08 , June 0,07 , July 0,06, 0,05, Aug 0,04, 0,03, Sept 0,026, 0,024 Nov 0,022, 0,019, 0,016, 0,013 Dec 0,012, 0,011, 0,010, 0,009 Jan 2024 0,008, 0,007, 0,006, 0,005, 0,004, 0,003, 0,002, 0,001, Feb 0,0007. 0,0005, 0,0003, 0,0001, Feb 23, 2024: 0,00000 Wellbutrin resume tapering: Apr 2024 31,6mg, 30,8, 30,0 , May 29,1, 28,2, July 23,7, Aug 22,6, 21,4, Dec 21,0, 20,5, 20,0 Jan 2025 19,6 mg Supplements: Fish Oil (3000mg), Magnesium 100 mg, 2 drops of Lavender Oil, only when feeling extreme anxiety. 50mg of L-Theanine only when severe discontinuation effects caused by Wellbutrin Please note this is NOT a medical advice. Discuss all your medical issues with a doctor who understands psychical drugs and really knows how to withdraw from them. I wish that you will find one.
FernanCC Posted August 31, 2023 Author Posted August 31, 2023 On 8/26/2023 at 1:27 PM, Go2zero said: Since when did you develop this diabetic profile? What are your blood sugar figures. When was this tested? And since when did you start gaining weight? Good questions, here; * The beginning and wheight gain: As some may know obesity and diabetes are strictly related, with around 80/90% people with diabetes having obesity. My wheight gain on antidepressants started early on, and it has been progressive and exponential, shooting up around 3 years in, as the literature mentions, with increased feelings of "bloatedness" and acidic response to foods, leading to gasses and excess of bile, even causing me to wake up more frecuently in the middle of the night to puke. This is yet another hint, due to the known correlation between gastrointestinal reflux disease (GERD) and diabetes. 04 years on SSRIS - Around October 2022 - I had an episode of "diabetic ketoacidosis" (DKA). For three to four days I was peeing every five minutes and I was feeling thirsty and dizzy. This was dismissed and undiagnosed by well-intentioned doctors that are educated on illness and medications, not health, if they did they their protocols would have ringed the alarm and suggested me to monitor and lower my blood levels, something I am doing now. (Unfortunately I don't have access to the blood results of the episode at the moment). * Testing and blood sugar levels; Since then I have had several blood tests, that I am judging per the guidelines of researchers specialized on prevention and curing pre-diabetes, here's a useful guide for your glucose levels that will help you control it; MORNINGS ON AN EMPTY STOMACH: (mg/dl) Diabetes; 125+ Pre-diabetes; 100-124 Pre-obesity; 86-99 Normal; 85 o or less. During last year my blood results after the DKA episode, have ranged from 90mg/dl to 100mg/dl, something a doctor would dismiss. I on the other hand, have found key correlations with my symptomatology. I started training again January 2023, at a rate at which I used to see results previously. Now 7 months of training, A month and half after cutting-off the medication (18/07) and starting a low carb diet (something new for me) there are no changes, which as made me look for evidence of permanent effects on the metabolism and I have been quite surprised with how plausible of a possibility it is, and the link to diabetic profile development. I will keep monitoring my blood-glucose levels on an empty stomach, and going down the rabbit hole to find the evidence behind the mechanisms that caused this and how to revert it. Regards. * Sertraline 100mg after breakfast for 05 years - quit cold turkey no symptoms. (August 2023). * Reinstatement of sertraline, immediately get start up symptoms and withdrawal until dose adjustment in 150mg (May 2024). * Currently tapering at 75mg.
Moderator Go2zero Posted September 1, 2023 Moderator Posted September 1, 2023 Hello @FernanCC, Thank you for the info. I would like to comment on your case from several corners. 1) This is a website to help people to get away from psychotropic medication in a safe way. We also assist people who have gotten away from such meds too fast. We advise them how to stabilise and how to heal from their withdrawal symptoms. 2) We are no doctors, so we cannot (and are not allowed to) give medical diagnoses Having said that and looking at your info, I want to say the following: 1) Your blood sugar figures are not in the range of diabetes. 2) Most SSRI's (like sertraline) are know to create (often much) weight gain. 3) Psychotropic medication and also withdrawal from such medication can have effects on blood sugar levels and also on the urge to urinate more than normal. These are common symptoms that lots of people on this medication have now and then. These symptoms may just come and go without a real cause. It is related to the use and withdrawal of this medication. See also here: https://www.survivingantidepressants.org/topic/9126-reactive-hypoglycemia-low-blood-sugar-and-symptoms/ https://www.mpg.de/593605/pressRelease20091028?fbclid=IwAR3uCJThPQIcokI5vIKT-KY8bkL__SfgwAePomc6zg_OihPEfXnpdSfqAJQ 3) I am worried about you cold turkey stopping 100 mg sertraline (which is double of a "normal dose") about 6 weeks ago. This may trigger heavy withdrawal symptoms within now and 2-3 months from now. Do you notice any withdrawal symptoms like: - change in sleep pattern? - headaches - nausea - change in anxiety - depressed feelings - heart palpitations - other physical or emotional changes 1993 Anafranil (Clomipramine) for a few months. Later in 1993 Paxil for a few months 1993- 2006 No medication 2006 Effexor, Cymbalta, some Benzo’s. All for short periods. Later in 2006 Lexapro (escitalopram) 10 mg and shortly after Wellbutrin XR 150mg, against side effects Lexapro Since 2006 until end of 2015: Several times on and off Lexapro and Wellbutrin and several slight dosage changes. Mostly taken dosages: 5mg Lexapro and 150mg Wellbutrin 2016 Dosage change Lexapro from 5mg to 2,5 mg. Wellbutrin stayed om 150mg November 2016 – April 2017 Down from 2,5mg to 0,6mg Lexapro (in steps) without much problems. Wellbutrin down from 150mg to 66mg. Also without much problems. April 2017 – March 2019 Lexapro 0,6 mg April 2017 - August 2018 Wellbutrin in small steps down from 66mg in to 37,5 mg . Quite heavy WD after each step. March 2019 – May 2019 Lexapro down from 0,6 to 0,3mg then Prozac to 0,6 mg switch because severe discontinuation effects (may also have been from Wellbutrin..) Wellbutrin down from 37,5mg to 35,3mg October 2019 Seroquel 12,5 mg for 4 weeks because of extreme sleeping problems, then weaning off in 2 weeks Prozac up dosage to 1,2 mg March 2020 Wellbutrin in 2 steps down from 35,3mg to 33,3mg Extreme withdrawal effects during 8 months. Stopped tapering Wellbutrin until total off Prozac. February 2020 – November 2020 Prozac down in steps from 1,2mg to 0,57mg. Jan 2021 : Prozac down to: 0,55> 0,53>0,51mg, Feb 0,47mg , Mar 0,42mg, Apr 0,37, longer hold because of WD symptoms July 0,36 and hold again, Sept 19 0,35, Sept 26 0,34mg, Oct 3 0,33mg Long hold of 172 days until March 2022 January 20, 2022: Wellbutrin from 33,3 to 32,4mg March 22, 2022 Prozac down from 0,33mg to: 0,30mg, Apr 0,29, May 0,28, 0,27, June 0,26, 0,25, July 0,24, 0,23, 0,22, 0,21, Aug 0,20, 0,19 Sep 0,18, Oct 0,17. 0,16, 0,15, Nov 0,14 Jan 2023 0,13, 0,12, 0,11 Feb 0,10, 0,09 Mar 0,08 , June 0,07 , July 0,06, 0,05, Aug 0,04, 0,03, Sept 0,026, 0,024 Nov 0,022, 0,019, 0,016, 0,013 Dec 0,012, 0,011, 0,010, 0,009 Jan 2024 0,008, 0,007, 0,006, 0,005, 0,004, 0,003, 0,002, 0,001, Feb 0,0007. 0,0005, 0,0003, 0,0001, Feb 23, 2024: 0,00000 Wellbutrin resume tapering: Apr 2024 31,6mg, 30,8, 30,0 , May 29,1, 28,2, July 23,7, Aug 22,6, 21,4, Dec 21,0, 20,5, 20,0 Jan 2025 19,6 mg Supplements: Fish Oil (3000mg), Magnesium 100 mg, 2 drops of Lavender Oil, only when feeling extreme anxiety. 50mg of L-Theanine only when severe discontinuation effects caused by Wellbutrin Please note this is NOT a medical advice. Discuss all your medical issues with a doctor who understands psychical drugs and really knows how to withdraw from them. I wish that you will find one.
FernanCC Posted September 2, 2023 Author Posted September 2, 2023 19 hours ago, Go2zero said: Hello @FernanCC, Thank you for the info. I would like to comment on your case from several corners. 1) This is a website to help people to get away from psychotropic medication in a safe way. We also assist people who have gotten away from such meds too fast. We advise them how to stabilise and how to heal from their withdrawal symptoms. 2) We are no doctors, so we cannot (and are not allowed to) give medical diagnoses Having said that and looking at your info, I want to say the following: 1) Your blood sugar figures are not in the range of diabetes. 2) Most SSRI's (like sertraline) are know to create (often much) weight gain. 3) Psychotropic medication and also withdrawal from such medication can have effects on blood sugar levels and also on the urge to urinate more than normal. These are common symptoms that lots of people on this medication have now and then. These symptoms may just come and go without a real cause. It is related to the use and withdrawal of this medication. See also here: https://www.survivingantidepressants.org/topic/9126-reactive-hypoglycemia-low-blood-sugar-and-symptoms/ https://www.mpg.de/593605/pressRelease20091028?fbclid=IwAR3uCJThPQIcokI5vIKT-KY8bkL__SfgwAePomc6zg_OihPEfXnpdSfqAJQ 3) I am worried about you cold turkey stopping 100 mg sertraline (which is double of a "normal dose") about 6 weeks ago. This may trigger heavy withdrawal symptoms within now and 2-3 months from now. Do you notice any withdrawal symptoms like: - change in sleep pattern? - headaches - nausea - change in anxiety - depressed feelings - heart palpitations - other physical or emotional changes Hello again, 1) I'm treating diabetes and obsesity as a continuum, and so should people whose wheight gain is being psychotropic induced, due to the commonality of the symptoms and the comorbidity. 2) Because of the unexplored nature of the mechanisms behind this phenomena, and having diabetic case in the family (caused by excess sugar consumption), I have become even more skeptical of how SSRIs may impact previous heathy body's well-managed proclivities. 3) I experienced KDA while on my medication, so it wasn't due to withdrawal, now that I am off it, I haven't had anything similar. 4) Thanks, exercise and eating healthy have been of huge help for this process. On the neurological side I've had effects that I don't want to emphasize but I'll comment: a.) I had paresthesia for 2-3 weeks. b.) Being a little more active, is difficulting me to reach a sleep-friendly state, but that seems organic. I don't foresee any of this increasing in the coming 02 months as "a)" has disappeared and "b)" is normal. No other changes whatsoever, I do consider myself lucky in that regard. Thanks for your concern. * Sertraline 100mg after breakfast for 05 years - quit cold turkey no symptoms. (August 2023). * Reinstatement of sertraline, immediately get start up symptoms and withdrawal until dose adjustment in 150mg (May 2024). * Currently tapering at 75mg.
Moderator Go2zero Posted September 2, 2023 Moderator Posted September 2, 2023 OK, thanks for making things more clear. 1 hour ago, FernanCC said: I don't foresee any of this increasing in the coming 02 months as "a)" has disappeared and "b)" is normal. It is great when you have come away from your medication without too much issues. If something would change here (let's hope not) you can always ask here for assistance if you want. Most often symptoms after stopping these meds occur 1-5 months after stopping. If that does not happen, you are a lucky person. I wish you so! Since we are "only" helping people to get away from psychotropic meds, I do not know if we can do something for you right now. Unless you have specific questions in that field. 1993 Anafranil (Clomipramine) for a few months. Later in 1993 Paxil for a few months 1993- 2006 No medication 2006 Effexor, Cymbalta, some Benzo’s. All for short periods. Later in 2006 Lexapro (escitalopram) 10 mg and shortly after Wellbutrin XR 150mg, against side effects Lexapro Since 2006 until end of 2015: Several times on and off Lexapro and Wellbutrin and several slight dosage changes. Mostly taken dosages: 5mg Lexapro and 150mg Wellbutrin 2016 Dosage change Lexapro from 5mg to 2,5 mg. Wellbutrin stayed om 150mg November 2016 – April 2017 Down from 2,5mg to 0,6mg Lexapro (in steps) without much problems. Wellbutrin down from 150mg to 66mg. Also without much problems. April 2017 – March 2019 Lexapro 0,6 mg April 2017 - August 2018 Wellbutrin in small steps down from 66mg in to 37,5 mg . Quite heavy WD after each step. March 2019 – May 2019 Lexapro down from 0,6 to 0,3mg then Prozac to 0,6 mg switch because severe discontinuation effects (may also have been from Wellbutrin..) Wellbutrin down from 37,5mg to 35,3mg October 2019 Seroquel 12,5 mg for 4 weeks because of extreme sleeping problems, then weaning off in 2 weeks Prozac up dosage to 1,2 mg March 2020 Wellbutrin in 2 steps down from 35,3mg to 33,3mg Extreme withdrawal effects during 8 months. Stopped tapering Wellbutrin until total off Prozac. February 2020 – November 2020 Prozac down in steps from 1,2mg to 0,57mg. Jan 2021 : Prozac down to: 0,55> 0,53>0,51mg, Feb 0,47mg , Mar 0,42mg, Apr 0,37, longer hold because of WD symptoms July 0,36 and hold again, Sept 19 0,35, Sept 26 0,34mg, Oct 3 0,33mg Long hold of 172 days until March 2022 January 20, 2022: Wellbutrin from 33,3 to 32,4mg March 22, 2022 Prozac down from 0,33mg to: 0,30mg, Apr 0,29, May 0,28, 0,27, June 0,26, 0,25, July 0,24, 0,23, 0,22, 0,21, Aug 0,20, 0,19 Sep 0,18, Oct 0,17. 0,16, 0,15, Nov 0,14 Jan 2023 0,13, 0,12, 0,11 Feb 0,10, 0,09 Mar 0,08 , June 0,07 , July 0,06, 0,05, Aug 0,04, 0,03, Sept 0,026, 0,024 Nov 0,022, 0,019, 0,016, 0,013 Dec 0,012, 0,011, 0,010, 0,009 Jan 2024 0,008, 0,007, 0,006, 0,005, 0,004, 0,003, 0,002, 0,001, Feb 0,0007. 0,0005, 0,0003, 0,0001, Feb 23, 2024: 0,00000 Wellbutrin resume tapering: Apr 2024 31,6mg, 30,8, 30,0 , May 29,1, 28,2, July 23,7, Aug 22,6, 21,4, Dec 21,0, 20,5, 20,0 Jan 2025 19,6 mg Supplements: Fish Oil (3000mg), Magnesium 100 mg, 2 drops of Lavender Oil, only when feeling extreme anxiety. 50mg of L-Theanine only when severe discontinuation effects caused by Wellbutrin Please note this is NOT a medical advice. Discuss all your medical issues with a doctor who understands psychical drugs and really knows how to withdraw from them. I wish that you will find one.
FernanCC Posted November 3, 2024 Author Posted November 3, 2024 Hello there, a note on hormone therapy and TRT for future reference: I've seen some comments and piece of advice in testimonials warning people of the danger of hormone replacement therapy (hrt), particularly trt in withdrawal, as it can further destabilize your nervous system sensitivity. Here's a post with my experience, so other people can share theirs. During tapering I went from 150mg to 25mg in the span of two months, I had to go back up to 75mg and it took me 40 days to stabilize. During this 40 days my doctor agreed that I needed more testosterone because I have congenital hypogonadism. My first shot 100mg enanthate injection, severely increased my symptoms for about a week and after that I waited and tried my regular dose of 50mg test, which also increased my symptoms but just slightly. Having started and stopped my 50mg gel therapy without any problems in the past, I'm led to believe that TRT during periods of increased sensitivity can be very destabilizing and problematic for the unbalanced nervous system. The bottom line seems to be, that during this periods of increased sensitivity any change specifically from systemic medications that involve the nervous system, can affect you in ways that it didn't affect you before... I'm afraid I will have to wait until the tapering ends to continue with my therapy. Regards. * Sertraline 100mg after breakfast for 05 years - quit cold turkey no symptoms. (August 2023). * Reinstatement of sertraline, immediately get start up symptoms and withdrawal until dose adjustment in 150mg (May 2024). * Currently tapering at 75mg.
FernanCC Posted November 3, 2024 Author Posted November 3, 2024 Is this topic approved? Can people interact with my post? * Sertraline 100mg after breakfast for 05 years - quit cold turkey no symptoms. (August 2023). * Reinstatement of sertraline, immediately get start up symptoms and withdrawal until dose adjustment in 150mg (May 2024). * Currently tapering at 75mg.
FernanCC Posted November 4, 2024 Author Posted November 4, 2024 Hello there, a note on hormone therapy and TRT for future reference: I've seen some comments and piece of advice in testimonials warning people of the danger of hormone replacement therapy (hrt), particularly trt in withdrawal, as it can further destabilize your nervous system sensitivity. Here's a post with my experience, so other people can share theirs. During tapering I went from 150mg to 25mg in the span of two months, I had to go back up to 75mg and it took me 40 days to stabilize. During this 40 days my doctor agreed that I needed more testosterone because I have congenital hypogonadism. My first shot 100mg enanthate injection, severely increased my symptoms for about a week and after that I waited and tried my regular dose of 50mg test, which also increased my symptoms but just slightly. Having started and stopped my 50mg gel therapy without any problems in the past, I'm led to believe that TRT during periods of increased sensitivity can be very destabilizing and problematic for the unbalanced nervous system. The bottom line seems to be, that during this periods of increased sensitivity any change specifically from systemic medications that involve the nervous system, can affect you in ways that it didn't affect you before... I'm afraid I will have to wait until the tapering ends to continue with my therapy. Regards. * Sertraline 100mg after breakfast for 05 years - quit cold turkey no symptoms. (August 2023). * Reinstatement of sertraline, immediately get start up symptoms and withdrawal until dose adjustment in 150mg (May 2024). * Currently tapering at 75mg.
FernanCC Posted November 4, 2024 Author Posted November 4, 2024 Just now, FernanCC said: Hello there, a note on hormone therapy and TRT for future reference: I've seen some comments and piece of advice in testimonials warning people of the danger of hormone replacement therapy (hrt), particularly trt in withdrawal, as it can further destabilize your nervous system sensitivity. Here's a post with my experience, so other people can share theirs. During tapering I went from 150mg to 25mg in the span of two months, I had to go back up to 75mg and it took me 40 days to stabilize. During this 40 days my doctor agreed that I needed more testosterone because I have congenital hypogonadism. My first shot 100mg enanthate injection, severely increased my symptoms for about a week and after that I waited and tried my regular dose of 50mg test, which also increased my symptoms but just slightly. Having started and stopped my 50mg gel therapy without any problems in the past, I'm led to believe that TRT during periods of increased sensitivity can be very destabilizing and problematic for the unbalanced nervous system. The bottom line seems to be, that during this periods of increased sensitivity any change specifically from systemic medications that involve the nervous system, can affect you in ways that it didn't affect you before... I'm afraid I will have to wait until the tapering ends to continue with my therapy. Regards. I'd like to know if this post is shown properly, and people can interact with it. * Sertraline 100mg after breakfast for 05 years - quit cold turkey no symptoms. (August 2023). * Reinstatement of sertraline, immediately get start up symptoms and withdrawal until dose adjustment in 150mg (May 2024). * Currently tapering at 75mg.
Moderator LotusRising Posted November 6, 2024 Moderator Posted November 6, 2024 Hi @FernanCC Yes, your post was approved. It was moved over here to your thread and yes, people can interact with it. On 11/3/2024 at 11:26 AM, FernanCC said: Having started and stopped my 50mg gel therapy without any problems in the past, I'm led to believe that TRT during periods of increased sensitivity can be very destabilizing and problematic for the unbalanced nervous system. Yes, it seems many women have this same problem when initiating hormone therapy. I agree, it's likely a good idea to wait until you're done tapering. Thank you for sharing your feedback. 2003-2009 on and off various SSRI's for short periods 2010-2011 Ativan 2013-2021 ativan 1-1.5mg 10-12x/month 2016 - Effexor 75mg, short-term 2021 Mar -Jun Buspar ADR at high dose, tapered 3 months Oct 22/21 - Direct switch ativan to clonazepam (don't do this) Tapered clonaz Oct/21 - Apr/23 - 0mg! "Believe that your tragedies, your losses, your sorrows, your hurt, happened for you, not to you. And I bless the thing that broke you down and cracked you open, because the world needs you open" - Rebecca Campbell *** Disclaimer: Please note, suggestions/comments are based on personal experiences. This is not medical advice. Please consult a knowledgeable practitioner to discuss decisions regarding your medical care *** *** Please do not send me PM's ***
FernanCC Posted November 6, 2024 Author Posted November 6, 2024 11 hours ago, LotusRising said: Hi @FernanCC Yes, your post was approved. It was moved over here to your thread and yes, people can interact with it. Yes, it seems many women have this same problem when initiating hormone therapy. I agree, it's likely a good idea to wait until you're done tapering. Thank you for sharing your feedback. Ah, Thank you so much I understand now. Thanks for the feedback as well. 1 * Sertraline 100mg after breakfast for 05 years - quit cold turkey no symptoms. (August 2023). * Reinstatement of sertraline, immediately get start up symptoms and withdrawal until dose adjustment in 150mg (May 2024). * Currently tapering at 75mg.
FernanCC Posted November 7, 2024 Author Posted November 7, 2024 On 11/6/2024 at 1:55 AM, LotusRising said: Hi @FernanCC Yes, your post was approved. It was moved over here to your thread and yes, people can interact with it. Yes, it seems many women have this same problem when initiating hormone therapy. I agree, it's likely a good idea to wait until you're done tapering. Thank you for sharing your feedback. I've seen both man and woman comments on this, I am a male, I'm curious that you have seen other cases with woman, hopefully this becomes more well known within the male community. * Sertraline 100mg after breakfast for 05 years - quit cold turkey no symptoms. (August 2023). * Reinstatement of sertraline, immediately get start up symptoms and withdrawal until dose adjustment in 150mg (May 2024). * Currently tapering at 75mg.
j1290 Posted November 8, 2024 Posted November 8, 2024 Hi @FernanCC Good to know about the TRT. I tapered off antidepressants 14 months ago, and began tapering finasteride the last few months. I thought it would be no big deal, and turned out to be surprisingly challenging. Symptoms have been similar to getting off of ADs. If I had known I might have waited a little longer before trying this. Good luck with your taper! I am not a doctor and do not offer any medical advice, only my own experience. Consult your physician. 2011-2015 tapered off 300MG of Effexor. Back in the Paxil Progress days. No rebound. 2005-2021: 450 mg Bupropion XL Daily 2021 Buporopion May 450mg/June 400mg/July 375mg/Aug 10th 360mg/ 2021 Dec - 150mg IR, 3x day = 450mg Bup, Heritage manufacturer-yellow color pill. 2022 May 3 - 3 x 150mg IR Bup, Avet brand(pharmacist said they merged with Heritage-orange color) -migraines REINSTATED-BACK TO MY LAST STABLE DOSE/TIME RELEASE 2022 June 5 - switched back to 3 x 150mg XL one time per day= 450 mg total Bup-Apotex brand FINISHED TAPER 2022 Aug 31 - 450MG to 412MG IR Bup//Sep. 28, 2022: 412mg to 375mg//Oct 26, 2022: 375mg to 365 mg//Nov 21, 2022: 365mg to 327mg//Dec 27, 2022: 327 mg to 290 mg//Dec 31, 2022: 290mg to 262mg//Jan 28, 2023: 262mg to 190mg//Feb. 19, 2023: 190mg to 140mg//Mar. 18, '23: 140mg to 100mg//can't remember the rest but jumped to zero Sept 5, 2023 CURRENT TAPER: Finasteride
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