NAVMMC: Bupropion rough ride down

[NAVMMC]

Hi Everyone, 

I’ve been on Bupropion 300xl since beginning of 2019 so almost 5 years. I also was taking Trazodone 50mg nightly for sleep and dropped to 25mg for a month or so then discontinuing it around June 2023. I also discontinued Losartan a blood pressure med around the same time. The doctor said my blood pressure was doing great and I could come off if, I wanted to. Around July 2023, I started to experience anxiety creeping in slowly due to a trigger thought from my past. I let it manifest and get bigger and bigger day by day until I went in full panic mode. It got so bad I went to VA hospital where I get care and they gave me Hydroxyzine for anxiety and panic attacks. I took it but it really didn’t help the anxiety was too strong at this point. I wasn’t sleeping very good. Had a couple more panic attacks. I then went back to the VA and saw mental health provider who told the Bupropion was causing the anxiety. He dropped me from 300xl to 150mg (75 ir X 2 a day).and started buspar 5mg morning and 5mg night. This was 21 Sep 23. I take the bupropion at 6am and 2pm. I also had a blood panel, thyroid test, and ekg to rule those out for the anxiety. All came back normal. I also started therapy. I stopped taking the buspar after a week. Didn’t really feel it was doing anything and made me feel weird. The anxiety has been debilitating at times it seems to be getting better slowly day by day. I’ve never had it this extreme in my 47 years. I’m retired from the Navy after 20 years and have had some stressful situations but this has really got me. I went back and saw mental health twice saying this a rough ride not being able to sleep a full night and the anxiety. They gave me rameron 30mg to take at night. I took it one time and then didn’t take it again. Didn’t want to get started on something else and the side effects of weight gain not worth it to me. Also tried Trazodone again 100mg just to see if I could get some relief made me too groggy and didn’t really help same with Hydroxyzine 25mg.  I just feel off, tired, irritable, frustrated, depression and anxiety comes and goes. Sometimes I have passing suicidal thoughts but would never act on them and I share this with my wife just so she knows what’s going through my head. They definitely scare me. Definitely affects your quality of life. I guess I just deal with it now. It’s no where near like before or at panic level. Oh and they want to put me on Prozac now. I haven’t touched it yet. I mentioned my sister is on it with good results so they feel that would be a good fit. I think I was dropped too fast on the bupropion and I’m feeling the withdrawal. It’s been five weeks now and just wanted to see what everyone’s input on this is. I want to try and be done with these meds and go natural. I don’t want to introduce more stuff that I’ll have to come off of. The biggest thing I’m dealing with is anxiety and poor sleep. I’ve looked at the taper schedule and guess I’m beyond the taper from 300xl spot. What are your recommendations at this point? I think it was odd I was dropped to 75ir x 2 a day. Any recommendations to ease the burden?  Many Thanks! 

[getofflex]

Hello, and welcome to SA.  We are a volunteer-run community of people who have been or are getting off of psychiatric drugs.  If you are looking to get off the psychiatric drugs, then you have come to the right place.   If I had to venture a guess, I would say that your symptoms are from reducing the bupropion too quickly be reducing it 50%, and probably also from the fast taper off trazodone.  However, I suspect that the other drugs that you have stopped and started may have also further contributed to your symptoms.  Once our nervous systems are destabilized by fast tapering, we tend to react poorly to other drugs, and these can destabilize us even further.  

 

Q: Just to clarify, the only psych drug you are currently taking is bupropion 150 mg (75 mg IR twice daily)?  Is this correct?  If not please give details.  

 

Can you please specify in your signature which drugs you are currently on - thank you.  

 

Here is some important information about how these drugs actually work.  This explains why we get symptoms from going off of these medications, and why it's so important to taper slowly and carefully, and be very cautious about changing our doses: 

 

How Psychiatric Drugs Remodel Your Brain

 

 

This helps you understand what withdrawal syndrome is: 

 

Video on Recovery from Psych Drugs

 

Windows and Waves Pattern of Stabilization

 

 

Tapering is best done extremely slowly, and we generally taper by 10% of the current dose no more than once every 4 weeks, so that the reduction becomes exponentially smaller.

 

 Why Taper by 10% of my Dosage 

 

It is possible that a partial updose of the bupropion might help you, but we need more information. 

 

Q: How is your eating, and daily functioning?  

 

Q: How many hours of sleep do you get each night on average?

 

 

I don't want to overwhelm you with information, so I will stop here for now.  

 

Edited October 31, 2023 by getofflex