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k4tniss: Zoloft tapering after about 6 weeks


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Posted (edited)

Hi everyone. 

 

I'm a 32-year-old woman and my journey with antidepressants started two years ago. I've had a long standing mixed anxiety-depressive disorder for which I did therapy on and off over the years. In 2022 I felt I couldn't handle therapy alone anymore and I went to see a psychiatrist. I was started on venlafaxine 37.5 mg on September 27th, 2022 and after a week the psy told me to increase to 75 mg. For a year I felt quite ok and I hadn't cried a single time. Due to anhedonia and excessive sweating I asked my psychiatrist to discontinue this medication and I was told to switch back to 37.5 mg for 6 weeks (from July 12th, 2023 to September 20th, 2023) and then stop. The day after the first missed dose was really awful. I couldn't stand up, read or eat. I was very nauseous and dizzy. It took me about 10 days to start recovering and I felt completely fine after 1-2 months. In the following months I've had recurring episodes of dizziness whenever I drank alcohol, even after just one pint of beer, which lasted for a few days, and decided to quit drinking completely.

 

Last March I had a relapse of anxiety and depression due to my father's diagnosis of brain cancer. I went back to the same psychiatrist and I was started on sertraline 25 mg on March 21st, 2024. After one week I was told to increase to 50 mg. The first two weeks were awful, but I think it was mostly because I had to face this dramatic change in my life. I was really anxious and I had severe headaches daily. I also took delorazepam 0.25 mg and ibuprofen 400 mg almost daily for about 2 weeks (from March 21st to April 4th) thinking I was experiencing tension headaches, but I had no relief. I also started noticing tremors in my hands at rest (especially on the left hand), random episodes of lip twitching and restless legs. Since these symptoms were similar to my father's, it caused me a lot of stress and I decided to start tapering on my own. On April 29th I switched to 25 mg and so far I've been good. Headaches have disappeared, my mood improved and the hand tremors are less evident. I'm having random episodes of diarrhoea and I've started taking probiotics.

 

Since I'm sick of antidepressants' side effects, I want to quit for good this time. Do you think it could be feasible to do a rapid taper since I've been on Zoloft for no more than 2 months? As for the diarrhea episodes, which could be a side effect of Zoloft, do you think it would be advisable to start taking magnesium? 

Edited by Emonda
Name to title

Mixed anxiety-depressive disorder.

- Sep 27, 2022 to Oct 04, 2022: Venlafaxine 37.5 mg.

- Oct 05, 2022 to Jul 11, 2023: Venlafaxine 75 mg.

- Jul 12, 2023 to Sep 20, 2023: Venlafaxine 37.5 mg. 

CT on Sep 21, 23 after psychiatrist's advice.

 

Relapse of depression and anxiety due to my father's diagnosis of glioblastoma. Started sertraline.

- Mar 21, 2024 to Mar 28, 2024: Sertraline 25 mg.

- Mar 29, 2024 to Apr 28, 2024: Sertraline 50 mg. Developed severe headache, not responding to NSAIDs and benzo. Decided to step down to 25 mg.

- Apr 29, 2024 - currently: Sertraline 25 mg. 

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  • Emonda changed the title to k4tniss: Zoloft tapering after about 6 weeks
  • Moderator

Hi k4tniss,

 

Welcome to SA. Thank you for summarizing your drug history in your signature.

 

On 5/6/2024 at 10:59 AM, k4tniss said:

Do you think it could be feasible to do a rapid taper since I've been on Zoloft for no more than 2 months?

 

Two months is long enough to develop dependency so we would recommend dropping no more than 10% of your previous dose per month. You can read more at Why taper by 10% of my dosage? This is especially important given all of the medication changes you have went through recently.

 

We have instructions on tapering Zoloft at Tips for tapering Zoloft (sertraline)

 

On 5/6/2024 at 10:59 AM, k4tniss said:

do you think it would be advisable to start taking magnesium

 

Magnesium is one of the supplements that we recommend during withdrawal. We have further info at Magnesium, nature's calcium channel blocker. You may want to start with a small dose to see how you tolerate it and make no other changes so you can assess properly.

 

Thanks,

 

Firefly

 

Pre- October 2022: Wellbutrin, Escitalopram, CitalopramSertraline, Adderall IR, Vyvanse, Propranolol, Buspar, Ativan, and Latuda

Oct 13, 2022 - Oct 24, 2022 and Oct 31, 2022 - Present: Zyprexa (2.5 mg). Jan 14, 2023 -> Began transition to liquid suspension. Jan 29, 2023 = 2.375mg -> Feb 12, 2023 = 2.25mg -> Feb 27, 2023 = 2.14mg -> Mar 12, 2023 = 2.025mg -> Mar 27, 2023 = 1.93mg -> Apr 10, 2023 = 1.82mg -> Apr 23, 2023 = 1.74mg -> May 7, 2023 = 1.64mg -> May 21, 2023 = 1.56mg -> June 4, 2023 = 1.48mg -> June 19, 2023 = 1.4mg -> July 2, 2023 = 1.33mg -> July 16, 2023 = 1.26mg -> July 31, 2023 = 1.2mg -> Aug 13, 2023 = 1.14mg -> Aug 27, 2023 = 1.08mg -> Sep 13, 2023 = 1.02mg -> Jan 22, 2024 = 0.97mg -> Feb 4, 2024 = 0.92mg -> Feb 19, 2024 = 0.87mg -> Mar 3, 2024 = 0.83mg -> Mar 17, 2024 = 0.78mg -> Mar 31, 2024 = 0.74mg -> Apr 14, 2024 = 0.7mg -> Apr 28, 2024 = 0.66mg -> May 12, 2024 = 0.63mg

Oct 14, 2022 - Present: Prozac (40mg) upped from 20mg on Nov 1, 2022.

Oct 31, 2022 - Present: Gabapentin (300mg 3x day) -> May 3, 2023 = 300mg 2x day -> Oct 1, 2023 = 570mg -> Oct 15, 2023 = 540mg -> Oct 29, 2023 = 510mg -> Nov 13, 2023 = 484mg -> Nov 27, 2023 = 460mg -> Dec 9, 2023 = 436mg -> Dec 24, 2023 = 414mg -> Jan 7, 2024 = 400mg

 

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