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reba22222: Decided Nov. 1, 2023 I wanted off all antidepressants after 32 years on at least half a dozen different ones . I’m a retired mental health professional.


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Spoke with my GP. Lost my psychiatrist when I retired in 2019 & she wouldn’t take my lower quality health insurance. My GP has been filling my scripts last 5 years. She made a few suggestions about titrating & I am now off Cymbalta for about 4 months and over last 9 months tapered down from 450 Wellbutrin (32 years) to 150mg. Then down to 150 3x per week and now doing 150 on Wednesdays & Sundays. That last step down over the last month not doing too well. Manicky symptoms like blasting people verbally in a rage over politics has happened 3x in the last month. I am on Oxcarbazapene 300 daily which I in ntend to continue indefinitely for now. How do I get to the endgame on bupropion. Body aches have been bad during AD withdrawal. I’m 65 years old. But have noticed feeling better & more energy over the last 9 months so my resolve is strong. Can 150’s be liquified to reduce more gradually?

1992-2024 Wellbutrin-450 mg daily, started reducing Nov. 1, 2023 (currently 150 mg 2x per week)

2018-2024 Cymbalta 60 mg daily-(off last 4 months);

2018-2024 Oxcarbazapene-300 mg daily currently.

2004-2018 Effexor (highest dose)

2017 Lithium for 6 months

1992-Proxac

I’m sure I took Zoloft & others in that 32 years but don’t remember specifics.

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  • Emonda changed the title to reba22222: Decided Nov. 1, 2023 I wanted off all antidepressants after 32 years on at least half a dozen different ones . I’m a retired mental health professional.
  • Moderator

Hi reba22222,

 

Welcome to SA. Thank you for summarizing your drug history in your signature.

 

22 hours ago, reba22222 said:

Then down to 150 3x per week and now doing 150 on Wednesdays & Sundays.

 

Can you clarify if you are only taking the Wellbutrin on Wednesdays and Sundays? If so, would encourage you to read NEVER SKIP DOSES TO TAPER.

 

Skipping doses can lead to instability and an increase in withdrawal symptoms so we recommend dosing consistently.

 

Thanks,

 

Firefly

 

Pre- October 2022: Wellbutrin, Escitalopram, CitalopramSertraline, Adderall IR, Vyvanse, Propranolol, Buspar, Ativan, and Latuda

Oct 13, 2022 - Oct 24, 2022 and Oct 31, 2022 - Present: Zyprexa (2.5 mg). Jan 14, 2023 -> Began transition to liquid suspension. Jan 29, 2023 = 2.375mg -> Feb 12, 2023 = 2.25mg -> Feb 27, 2023 = 2.14mg -> Mar 12, 2023 = 2.025mg -> Mar 27, 2023 = 1.93mg -> Apr 10, 2023 = 1.82mg -> Apr 23, 2023 = 1.74mg -> May 7, 2023 = 1.64mg -> May 21, 2023 = 1.56mg -> June 4, 2023 = 1.48mg -> June 19, 2023 = 1.4mg -> July 2, 2023 = 1.33mg -> July 16, 2023 = 1.26mg -> July 31, 2023 = 1.2mg -> Aug 13, 2023 = 1.14mg -> Aug 27, 2023 = 1.08mg -> Sep 13, 2023 = 1.02mg -> Jan 22, 2024 = 0.97mg -> Feb 4, 2024 = 0.92mg -> Feb 19, 2024 = 0.87mg -> Mar 3, 2024 = 0.83mg -> Mar 17, 2024 = 0.78mg -> Mar 31, 2024 = 0.74mg -> Apr 14, 2024 = 0.7mg -> Apr 28, 2024 = 0.66mg -> May 12, 2024 = 0.63mg -> May 27, 2024 = 0.6mg -> June 9, 2024 = 0.57mg -> June 24, 2024 = 0.54mg -> July 6, 2024 = 0.51mg

Oct 14, 2022 - Present: Prozac (40mg) upped from 20mg on Nov 1, 2022.

Oct 31, 2022 - Present: Gabapentin (300mg 3x day) -> May 3, 2023 = 300mg 2x day -> Oct 1, 2023 = 570mg -> Oct 15, 2023 = 540mg -> Oct 29, 2023 = 510mg -> Nov 13, 2023 = 484mg -> Nov 27, 2023 = 460mg -> Dec 9, 2023 = 436mg -> Dec 24, 2023 = 414mg -> Jan 7, 2024 = 400mg

 

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Yes and it doesn’t feel right. I just found this  site. Don’t have health insurance this month so trying to figure stuff out on my own. Can’t afford a doctor right now.

1992-2024 Wellbutrin-450 mg daily, started reducing Nov. 1, 2023 (currently 150 mg 2x per week)

2018-2024 Cymbalta 60 mg daily-(off last 4 months);

2018-2024 Oxcarbazapene-300 mg daily currently.

2004-2018 Effexor (highest dose)

2017 Lithium for 6 months

1992-Proxac

I’m sure I took Zoloft & others in that 32 years but don’t remember specifics.

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How to go from Bupropion 150’s to the endgame without skipping doses would be helpful information. Thank you for your kind reply previously.

1992-2024 Wellbutrin-450 mg daily, started reducing Nov. 1, 2023 (currently 150 mg 2x per week)

2018-2024 Cymbalta 60 mg daily-(off last 4 months);

2018-2024 Oxcarbazapene-300 mg daily currently.

2004-2018 Effexor (highest dose)

2017 Lithium for 6 months

1992-Proxac

I’m sure I took Zoloft & others in that 32 years but don’t remember specifics.

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  • Moderator

How long have you been dosing twice a week?

 

We have information for tapering Bupropion at Tips for tapering off bupropion (Wellbutrin, IR, SR, XR, XL, Zyban).

 

Are you on the XR version?

 

Pre- October 2022: Wellbutrin, Escitalopram, CitalopramSertraline, Adderall IR, Vyvanse, Propranolol, Buspar, Ativan, and Latuda

Oct 13, 2022 - Oct 24, 2022 and Oct 31, 2022 - Present: Zyprexa (2.5 mg). Jan 14, 2023 -> Began transition to liquid suspension. Jan 29, 2023 = 2.375mg -> Feb 12, 2023 = 2.25mg -> Feb 27, 2023 = 2.14mg -> Mar 12, 2023 = 2.025mg -> Mar 27, 2023 = 1.93mg -> Apr 10, 2023 = 1.82mg -> Apr 23, 2023 = 1.74mg -> May 7, 2023 = 1.64mg -> May 21, 2023 = 1.56mg -> June 4, 2023 = 1.48mg -> June 19, 2023 = 1.4mg -> July 2, 2023 = 1.33mg -> July 16, 2023 = 1.26mg -> July 31, 2023 = 1.2mg -> Aug 13, 2023 = 1.14mg -> Aug 27, 2023 = 1.08mg -> Sep 13, 2023 = 1.02mg -> Jan 22, 2024 = 0.97mg -> Feb 4, 2024 = 0.92mg -> Feb 19, 2024 = 0.87mg -> Mar 3, 2024 = 0.83mg -> Mar 17, 2024 = 0.78mg -> Mar 31, 2024 = 0.74mg -> Apr 14, 2024 = 0.7mg -> Apr 28, 2024 = 0.66mg -> May 12, 2024 = 0.63mg -> May 27, 2024 = 0.6mg -> June 9, 2024 = 0.57mg -> June 24, 2024 = 0.54mg -> July 6, 2024 = 0.51mg

Oct 14, 2022 - Present: Prozac (40mg) upped from 20mg on Nov 1, 2022.

Oct 31, 2022 - Present: Gabapentin (300mg 3x day) -> May 3, 2023 = 300mg 2x day -> Oct 1, 2023 = 570mg -> Oct 15, 2023 = 540mg -> Oct 29, 2023 = 510mg -> Nov 13, 2023 = 484mg -> Nov 27, 2023 = 460mg -> Dec 9, 2023 = 436mg -> Dec 24, 2023 = 414mg -> Jan 7, 2024 = 400mg

 

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I went from Bupropion HCL XL on Monday, Wednesday, Friday (for 2-3 months) to Wednesday and Sunday a month ago (June 2024). I see from this site that skipping doses was a mistake. Thank you for the link. I will read it carefully.

1992-2024 Wellbutrin-450 mg daily, started reducing Nov. 1, 2023 (currently 150 mg 2x per week)

2018-2024 Cymbalta 60 mg daily-(off last 4 months);

2018-2024 Oxcarbazapene-300 mg daily currently.

2004-2018 Effexor (highest dose)

2017 Lithium for 6 months

1992-Proxac

I’m sure I took Zoloft & others in that 32 years but don’t remember specifics.

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On 7/7/2024 at 9:30 AM, reba22222 said:

How do I get to the endgame on bupropion.

I can tell you how I did it. I was taking 450mg of the XL, so I talked to my doctor about tapering and they agreed to prescribe me the IR tablets.  I got the prescription filled at honeybee pharmacy, so I could choose the manufacturer that agreed with me the best and it wouldn't get switched around like my insurance does.  They were affordable.  I took the IR 3 times per day.  

 

I slowly tapered down to somewhere around 100mg, then I started doing a liquid taper, which is actually quite easy and convenient once you get the hang of it.  

 

Thats it in a nutshell.   I took it for decades as well.  I didn't find it particularly easy to get off of.  I can tell you that all my symptoms have improved since I got to zero about 10 months ago.   

 

Good luck with whatever you decide!

I am not a doctor and do not offer any medical advice, only my own experience.  Consult your physician.

2011-2015 tapered off 300MG of Effexor.  Back in the Paxil Progress days.  No rebound.   

2005-2021:  450 mg Bupropion XL Daily

2021 Buporopion May 450mg/June 400mg/July 375mg/Aug 10th 360mg/

2021 Dec - 150mg IR, 3x day = 450mg Bup, Heritage manufacturer-yellow color pill. 

2022 May 3 - 3 x 150mg IR Bup, Avet brand(pharmacist said they merged with Heritage-orange color) -migraines

REINSTATED-BACK TO MY LAST STABLE DOSE/TIME RELEASE

2022 June 5 - switched back to 3 x 150mg XL one time per day= 450 mg total Bup-Apotex brand

CURRENT TAPER 2022 Aug 31 - 450MG to 412MG IR Bup//Sep. 28, 2022: 412mg to 375mg//Oct 26, 2022: 375mg to 365 mg//Nov 21, 2022: 365mg to 327mg//Dec 27, 2022: 327 mg to 290 mg//Dec 31, 2022:  290mg to 262mg//Jan 28, 2023:  262mg to 190mg//Feb. 19, 2023:  190mg to 140mg//Mar. 18, '23:  140mg to 100mg//can't remember the rest but jumped to zero Sept 5, 2023

 

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