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Serotonin down regulation / withdrawals 2023 radomised trials of 580 people


mickde1

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Hi all

Im 8 years and 9 months into recovery but  still not out of the woods yet  i'm physically  healthy eating mostly a healthy diet  and at the   moment on a very low dose of ashwagandha that just  enough to keep me relaxed and better quality sleep at a higher dose but still below thrapeutical amount  i found  it has a down regulations effect of serotonin experiencing  in a loss of libido and sex interest 

 

 This topic and the studies information is the first that i've come across

 

https://link.springer.com/article/10.1007/s40263-022-00960-y

 

I've been medication free for 8 years and 9 months  months , stopped   med's December 14th 2015,  history  20 years on  Prozac 80mg & Moclobemide 150 mg  per day,  stopped  Moclobemide sometime in 2012 then about a year later lowered Prozac  dose to 20mg  per day, then changed to Paroxetine, then change to a Mirtazapine,  then change to Lexapro,  then changed to Brintellix,  then changed to Edronax  all at 10mgs or less  over a period of about  year,   Edronax tapered 4mg to 2mg over  10 weeks, 2 mg for 8 weeks 1 mg for 10 weeks  stopped all meds completely 14 December 2015  3 months later all HELL broke loose 

18 Jan 2019 reinstated Prozac  .25 mg then ceased 8/8/20

 

 

 

 

I've been medication free for 65 months and a half months as posted of May 30th 2021 , stopped   med's December 14th 2015,  history  20 years on  Prozac 80mg & Moclobemide 150 mg  per day,  stopped  Moclobemide sometime in 2012 then about a year later lowered Prozac  dose to 20mg  per day, then changed to Paroxetine, then change to a Mirtazapine,  then change to Lexapro,  then changed to Brintellix,  then changed to Edronax  all at 10mgs or less  over a period of about  year,   Edronax tapered 4mg to 2mg over  10 weeks, 2 mg for 8 weeks 1 mg for 10 weeks  stopped all meds completely 14 December 2015  3 months later all HELL broke loose 

18 Jan 2019 reinstated Prozac  .25 mg then ceased 8/8/20

 

 

 

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