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Poll: Did you get sexual dysfunction (PSSD) or emotional anesthesia after you stopped all drugs?


Did you get sexual dysfunction (PSSD) or emotional anesthesia after you stopped all drugs?  

19 members have voted

  1. 1. Did you develop PSSD after you stopped a drug?

    • Yes
      12
    • No
      7
  2. 2. If you developed PSSD, did you also have emotional anesthesia?

    • Yes
      10
    • No
      9
  3. 3. Did you develop emotional anesthesia but not get PSSD?

    • Yes, developed emotional anesthesia but not PSSD
      0
    • No, did not develop emotional anesthesia or PSSD
      0
    • Developed emotional anesthesia with PSSD
      2
    • Developed PSSD but not emotional anesthesia
      1

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  • Poll closes on 02/10/2025 at 08:00 AM

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  • Administrator
Posted (edited)

Hello. Please respond to this poll about sexual dysfunction or emotional anesthesia after going off any antidepressant or psychiatric drug, not just SSRIs.

 

Post-drug sexual dysfunction may be a continuation of the sexual dysfunction you felt while taking the drug or it may be a new sexual dysfunction. Post-drug, it is generally described as an unusual lack of sexual sensation that interferes with normal functioning.

 

Emotional anesthesia is a complete deadening of feelings, not just feeling down or lethargic or "blunted". 

 

Note: PSSD means Post-SSRi Sexual Dysfunction, and it occurs only after you've gone off the drug. If you are taking any drugs, sexual dysfunction might be an adverse drug effect, not PSSD.

 

Thank you.

 

 

Edited by Altostrata
restated ambiguous question

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

Posted

Is "emotional anesthesia" the same as anhedonia?

Sertraline (Zoloft) 2004: 50mg (Nov); 2005: 100mg (Feb), 200mg (Jul); 2006: 100mg (Feb); 2007-2010: 150mg; 2011: 100mg (Jun); 2012: 75mg, 100mg; 2013: 125mg; 2014: 100mg, 75mg, 50mg; 2015: 75mg, 100mg, 125mg, 150mg; 2018: 149mg (4 Jan) - 128mg (3 Dec); 2019: 125mg (20 Jun); 2022: ↘︎ 123mg (9 Feb) - 111mg (28 Dec); 2023: ↘︎ 110mg (4 Jan) - 59mg (27 Dec); 2024: ↘︎ 58mg (1 Jan) - 12mg (25 Dec); 2025: ↘︎ 11mg (18 Jan), ↘︎ 10mg (4 Feb); ↘︎ = Daily micro-taper (fractions of a mg).

Temazepam 2004: ?mg - 0mg.

Alprazolam (Xanax) 2007: 0.5mg - 4mg - 0mg.

Quetiapine (Seroquel) 2008: 25mg - 75mg; 2009: 50mg - 0mg.

Dexamphetamine 2013: 5mg - 0mg.

Modafinil 2017: 100mg - 0mg.

 

QUIT: Coffee (09 Mar '22) | Alcohol (11 Mar '22) | Vitamin supplements (14 Mar '22) | OTC medications (14 Mar '22) | Herbal and mushroom supplements (14 Dec '22)

 

"Discipline will set you free"

  • Administrator
Posted

Anhedonia is a rather vague term used by psychiatry.

 

We coined "emotional anesthesia" for an unprecedented, more intense and global deadening of all positive emotions that is often seen in withdrawal syndromes. 

 

"Emotional anesthesia" is not just feeling blah, disengaged, or bored.

 

@Snowblind Please shorten your signature, it demands a lot of scrolling to get past it.

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

Posted
On 1/12/2025 at 5:26 AM, Altostrata said:

Anhedonia is a rather vague term used by psychiatry.

 

We coined "emotional anesthesia" for an unprecedented, more intense and global deadening of all positive emotions that is often seen in withdrawal syndromes. 

 

Hi Alto, good to see you here and thank you for your ongoing work fighting the good fight on behalf of us all!

 

Based on the quoted text, is it correct that "emotional anesthesia" means that one feels no positive emotions while still feeling negative emotions? This is what trips me up about the term, where "anesthesia" strikes me as a misnomer. I only very rarely feel any semblance of positive emotions and certainly feel all the negative emotions quite intensely and overwhelmingly -- would gladly welcome some anesthetic relief (numbing) from the latter! Perhaps I do not understand the way "anesthesia" is being used.

 

I've answered the poll above. I wasn't sure how to answer question 3. I did have PSSD for a number of years. It has basically resolved. I have also long had persistent, stubborn severe emotional distress/anguish. I didn't notice any particular connection between "emotional anesthesia" and the PSSD, although they were concurrent (and the experience of PSSD was not exactly mood-enhancing). The intensely, overwhelmingly negative emotional/mental landscape continues to a nightmarish degree even though I have been drug-free for years.

 

Is PGAD considered part of PSSD? Or is it considered a distinct phenomenon? In my case they blended and overlapped. For what it's worth, I'd characterize PGAD as a subset of PSSD. The PGAD "mixed" phase preceded a prolonged period of "pure" PSSD, where PGAD was characterized by its own singular dysfunction although without the same level of associated dysphoria as subsequent non-PGAD PSSD.

1996-2018 - misc. polypharmacy, incl. SSRIs, SNRIs, neuroleptics, lithium, benzos, stimulants, antihistamines, etc. (approx. 30+ drugs)

2012-2018 - 10mg lexapro/escitalopram (20mg?)    Jan. 2018 - 10mg -> 5mg, then from 5mg -> 2.5mg, then 0mg  -->  July 2018 - 0mg

2017(?)-2020 - vyvanse/lisdexamfetamine 60-70mg    2020-2021 - 70mg down to 0mg  -->  July 2021 - 0mg

March-April 2021 - vortioxetine 5-10mg (approx. 7 weeks total; CT)  -->  April 28th, 2021 - 0mg

August 2021 - 2mg melatonin   August 1, 2022 - 1mg melatonin   March 31, 2023 - 0mg melatonin

2024 supplements update: electrolyte blend in water sipped throughout the day; 1 tsp cod liver oil blend (incl. vit. A+D+E) w/ breakfast; calcium; vitamin C+zinc

 

Courage is fear that has said its prayers.  - Karle Wilson Baker

love and justice are not two. without inner change, there can be no outer change; without collective change, no change matters.  - Rev. angel Kyodo williams

Holding multiple truths. Knowing that everyone has their own accurate view of the way things are.  - text on homemade banner at Afiya house

 

I am not a medical professional; this is not medical advice. 

Posted

My PSSD started right after discontinuation and ended about 5 months into withdrawal, but at 2.5 years I still have emotional anesthesia. It's somewhat tolerable early in the day and gets progressively worse until I go to bed.

  • 2011 (age 10) - 2019 100mg Sertraline then cold turkey'd. Took it very sporadically. 
  • June 2021 - July 2022 50mg Sertraline then cold turkey'd again
Posted
On 1/9/2025 at 10:55 PM, Altostrata said:

Hello. Please respond to this poll about sexual dysfunction or emotional anesthesia after going off any antidepressant or psychiatric drug, not just SSRIs.

 

Post-drug sexual dysfunction may be a continuation of the sexual dysfunction you felt while taking the drug or it may be a new sexual dysfunction. Post-drug, it is generally described as an unusual lack of sexual sensation that interferes with normal functioning.

 

Emotional anesthesia is a complete deadening of feelings, not just feeling down or lethargic or "blunted". 

 

Note: PSSD means Post-SSRi Sexual Dysfunction, and it occurs only after you've gone off the drug. If you are taking any drugs, sexual dysfunction might be an adverse drug effect, not PSSD.

 

Thank you.

 

 

Alto what are your thoughts on the prognosis of PSSD? I remember before that you were of the opinion that all or at least most recovered. Do you still think that? 

Jan 2017 (17 years old) Prozac 10 mg : May 2018 rapid taper to 0mg : August 2018 low dose hydrocodone for 1 week- sept 2018: began taking the legal supplement Kratom (partial opiate agonist, serotonin receptor agonist, 5-HT2c blocker increasing dopemine and norepinephrine) for back pain : October 2018- reinstated 10 mg Prozac Jan 2019 upped to 20 mg prozac
August 2019: upped to 40 mg prozac 
Through 2020 Worked up to 25 gpd krat
September 2020: dropped Kratom dose by 10gpd
Sept 2020- Jan 2021: tapered krat to 7gpd
January 2021: switched to lexapro 10 mg
May 2021:  delayed withdrawal symptoms

May-January- tapered Krat to 0.8 mg, jumped in late Jan 

April 2022: drop lexapro and added 10 mg Prozac 

July 7: 15 mg Prozac 

  • Administrator
Posted

Please use search to review my comments on this subject.

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

Posted

Hi, I stopped using drugs last year, which I was on almost all of 2024 with multiple psychotropic drugs, I took pristiq for 15 days, which showed me sexual dysfunction, and when I stopped it I was still the same, today I continue with the same sexual dysfunction and genital sequence, plus a lot of symptoms that do not improve, it should be noted that they prescribed me welbutrin, which was only a patch for only 15 days. I no longer take psychotropic drugs, but it accompanies me. INSOMNIA TINNISM COGNITIVE DETERIORATION EXTREME SEXUAL DYSFUNCTION (No genital numbness). ANHEDONIA.. I am taking doses of Omega 3 wings, vitamin C, and other supplements to increase sexual function but this does not improve, I am only 23 years old, I do not know what to do and I wanted to end this suffering that drugs left me, I would NEVER have taken them. What do you recommend I take more? I don't know what to do. I want my old life back.

 

Sorry for my English, I'm from Colombia, I use a translator...

Marzo 2024 - Sertralina 50 mg por 4 días, suspensión inmediata, efectos como: desconexión total en las emociones, apatía. Todo mejoró y volvió a la normalidad, a los 20 días amanecí con un TAG que nunca relacioné con la medicación anterior tomada, insomnio, mente en blanco, cambios bruscos de temperatura, inicio de psicosis con voces, etc... Después Sedoxil 1mg hasta abril 2024, suspensión brusca por deterioro cognitivo de corta duración, el psiquiatra nunca me advirtió sobre esto y lo que provocaba la medicación. Luego de tomar Escitalopram genérico por 15 días al aumentar la dosis fui presentando síntomas como demencia, luego: Pristiq 50 mg con quetiapina 25 y 50 mg bloqueo mental, disfunción sexual, me entero de la relación del medicamento con pssd, intento suspender la medicación dividiendo las pastillas de pristiq con ayuda de un psicólogo clínico en menos de dos semanas, un mal procedimiento me dejó con un problema de atención y entré en estado de abstinencia, me recetan levomepromazina en gotas para ayudarme a dormir, más deterioro cognitivo, decidí suspenderlo y buscar otro médico. Luego welbutrin con lorazepam en gotas para dormir, mejoró y corrigió algo que dejó el pristiq, dejó de funcionar al tiempo y fui cada vez más enfermo con síntomas secundarios, actualmente octubre 2024 suspensión de welbutrin lo logre dejar y estuve mal una semana, luego todo empezó a mejorar hasta la ruptura de una relación (8 de noviembre de 2024) cayendo totalmente casi al suicidio, me hospitalizaron y me introdujeron medicamentos a la fuerza.
-Clozapina inyectada 5mg 1 dosis
-abilify inyectado 5mg 1 dosis
-Alpraxolam inyectado

Actualmente me reiniciaron a la fuerza el WELBUTRIN 150 mg y agregaron onlazapina 5 mg para "dormir".

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