Apparently the quinine in tonic water can work for restless legs: http://www.peoplespharmacy.com/2010/10/11/is-quinine-in-tonic-water-safe/   Caution: If you have tinnitus, quinine can aggravate it. Is there enough in tonic water to cause a problem? I don't know.   Discussion of various home remedies for RLS http://www.myhomeremedies.com/topic.cgi?topicid=319   More home remedies http://health.howstuffworks.com/wellness/natural-medicine/home-remedies/home-remedies-for-restless-legs-synd