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  1. A live interview last night about PSSD awareness on Juliemadblogger Radio. It has been recorded and widely available for free on demand at http://www.blogtalkradio.com/juliemadblogger/2017/10/22/guest-from-uk-pssd-sexual-dysfunction-from-psychiatric-drugs You can also download the mp3 version that can be listened to offline by clicking the download icon at the top too... (top right) Please share and distribute as widely as possible on social media and websites. And help spread PSSD Awareness.
  2. Hello, I was diagnosed with fibro in 1994. I was just diagnosed by a rheumatologist with CSS - central sensitivity syndrome. A central nervous system disease/disorder that makes people hypersensitive to almost everything. Here are two studies that might be of interest: Fibromyalgia and Overlapping Disorders: The Unifying Concept of Central Sensitivity Syndromes by Muhammad B Yunus, MD -also: clinical review and education- JAMA April 16, 2014 volume 311, number 15 - Fibromyalgia A Clinical Review by Daniel J Clauw, MD. These articles show how the central nervous system plays a huge role in why so many of us have fibromyalgia CFS/ME, MCS-Multiple Chemical Sensitivities, etc. This explains why I've had so much trouble with antidepressants, benzodiazepines, and withdrawals, along with so many other physical and emotional symptoms
  3. I don't profess to know what it's like to live with anxiety, depression, or "medically diagnosed psychosis" in any form. Nor have I experienced the brain numbing side effects of the so called "Happy Pills" that are dished out like lollies to children and adults alike. And now Babies are the next largest growing market for these personality fixers. I live on the "Otherside". Firstly, I am the Mother, who against all pleading, and arguing with Doctor's (of all ranks) to not put my then "coming of a Meth Addiction" Son, onto Anxiety medication, was ignored. We are the people who stand by and watch as our loved one's fall apart slowly, in front of our eyes. The one's who are powerless to help and to fix it, because we are "out ranked" by the people who are supposed to know what is best. What I have done, is make it my life's work to understand Addiction and Anxiety - including coming off of these debilitating drugs and what happens within the brain from an unconscious, neuroscience and being in control of yourself perspective. I found this site because I too was looking for some answers on "cold turkey withdrawal". My Son decided to go cold turkey off of his Antidepressants 3 1/2 weeks ago. His decision? because he was sick of the night terrors, cold sweats and feeling like he was constantly in a fog. He asked me to help in my professional capacity and together we got through the hard parts. He still has a way to go, and I am not recommending going "cold turkey" However, what I can say is this: There IS clarity at the end of that foggy tunnel, allow your mind and body to adjust to this new drug free you. It will take sometime, it will happen. I am here to lend support just like all of the other amazing people in this forum . If I am able to support you by giving you any tools that will assist you. I will. Here is something I would like to share with you; You don't need to be strong. Realise, really understand and see, just how self empowered you have become, by being on this journey. And that you are absolutely AWESOME!!!! In those moments of doubt and grayness, give yourself permission to acknowledge just how amazing you are. You have come this far, keep going! xx
  4. fema4psychiatrists

    Sterilized when Young in UK by Psych Drugs

    I was interviewed on the everyday psychvictims project. Share if you care.
  5. Hello . I took anti depressants ,anti anxiety , syzophenia medicines for one month . One doctor prescribed me these medicines after knowing the side effects in inherent I was scared to eat it and didn't want to eat it . I started suffering from acidity after eating I felt scared all the time 24/7 . My legs shivered atoagocally when I tried sitting still , my brain stopped working normally , I stopped eating properly , I stopped caring about everything , then I went to another psychiatrist . He told me I have been prescribed wronge medicines . Which is the syzophenia one cause I don't have syzophenia . I was shocked :((( cause I already ate it for 1 month ... I had to leave school when I promoted to class 9 cause I couldn't concentrate at all it's been a year I threw away those medicines and also complained to the psychiatrist about the side effects . I had brain pain after I stopped taking the 1 mg medicines each . Now I don't have brain pain . every time I tried studying my brain pained I was always a good student first time ever I failed I cried day and nighth I couldn't study and remember things whereas I was the best student layer after seeing my state my parents supported me and complained to psychiatrist . I'm still crying while writing this I thought I will never ever recover and I can't live with brain pain forever . I cried everyday and slowly the brain pain went . I'm healing . Thankgod I didn't eat it for 3 months but I completed 50% course . I think I'll fail next year too . Will I ever recover full my teachers noticed changes in me and told my parents what happened to me . I have heard from 2 people they suffered same things but got addicted to medicines
  6. In-depth article about how genetics informs how you process drugs, and also how it affects drug interactions, and the genetic tests used to determine if you will likely react badly to a drug or not. It's written by a forensic medical examiner. I've only skimmed it but seems well worth a read through. https://www.madinamerica.com/2017/01/cyp-testing-prevent-dangerous-adverse-drug-reactions/ CYP Testing to Help Prevent Dangerous Adverse Drug Reactions By Selma Eikelenboom-Schieveld, MD January 24, 2017 Readers of this website might be aware that antidepressants can cause suicide, other violent behavior and even homicide. These can be side effects or adverse drug reactions from the medication taken. Not only can antidepressants cause these side effects, but basically every psychoactive medication can put patients at risk. Few people may know that there are DNA tests that can identify individuals who might be prone to these adverse drug reactions.1 To understand what kind of information such a test would provide, it might be helpful to explain the science behind these DNA tests. In general, human cells contain 23 pairs of chromosomes. The father donates half of the chromosomes; the other half comes from the mother. Every chromosome contains many genes. A gene is the part of the DNA that codes for proteins, and proteins cause hereditary characteristics to be expressed. A gene can have two forms, called alleles. If someone inherits the same allele from the father and the mother, the person is called homozygous for that trait; if they are different, the person is heterozygous. Medication needs to be metabolized to be expelled from the body. This is done by certain proteins called enzymes. Most medications that interact with brain chemistry are metabolized by an enzyme system called Cytochrome P450 (also known as CYP450 or P450). There are many different P450 enzymes, and they are divided into families and subfamilies. Cytochrome P450 family names are denoted by an Arabic number (e.g., CYP2), the subfamily by a Roman uppercase letter (e.g., CYP2D), and the individual enzymes by another Arabic number (e.g., CYP2D6). The alleles are indicated with an asterisk and a number, separated by a forward slash. More at above link...
  7. Hi, I think lately I've been under covert medication. Anybody recognizes these symptoms with any antidepressant or antipsychotic? Thank you in advance. -Extreme photophobia (light hurts even at night with street lights or car lights) -Excess of fat in your stools (daily) (soft, greasy and pale yellow stools) -Urgency to urinate constantly -Lack of concentration -Feeling cold all the time but sometimes you feel heat intolerant (even when you are in direct sunlight you feel almost hypothermia) -Acathisia or restless sensation all the time -Racing thoughts all the time -Extreme Insomnia -Unability to achieve a lasting erection and difficult to achieve orgasms -Darkening and thickening of your hair, not only body hair but face and head (you have brown hair and the suddenly you have black thick and damaged-like hair) -You feel you cannot learn easily and you have a really hard time memorizing things you could easily do -You keep sweating and sweating but at the same time you have dry skin and sometimes lack of sweating in your face (cold, clammy skin) -You leave a weird odor in your clothes, always, even if you bathe yourself well -Dry mouth and bad breath even if you wash your teeth -ANNOYING muscle tightness (it feels like you just cannot relax your muscles and all the time you feel like if they are pulling) -Feeling like walking as a drunk or you feel you don't have stability as you walk -Lack of judgment, (getting very emotional out of nothing or not really seeing the whole picture of situations) -You feel like you are more complaisant that normal (agreeing things you normally don't and feeling like you worry about what others can say about you when you normally don't) -Abnormal euphoria just because everything -Mood changes (from euphoria and being very emotional to rage and depression) -Losing sensation of your body (you touch yourself but it feels like you don't feel anything) -Pallor -Abnormal healing of wounds (I could have a cut but the wound won't heal as fast as before, it would just take weeks to properly close) -Wanting to talk and verbalize everything nonstop -Constant gum bleeding (very sensitive just by brushing teeth) -Strange change in food's taste -Fatigue alterning with periods of extreme energy and I-can-do-it-all periods -Feeling like you were running and agitated most of the time -You cannot stop moving your feet -Weight gain -Dilated pupils -Dry lips -Numbed tongue -Difficulty in speaking (like you don't know the words to describe something totally easy and normal, stuttering) -Dilated arm veins -Ear buzzing -Increased sensitivity to normal noises -Difficulty to do maths -Eye bags and looking ill in general. -Feeling suicidal -Looking yellow sometimes -Having foam in your urine sometimes. -Zero sexual arousal (it is like you do not feel aroused or have erections as you normally do) In general, feeling like you are totally drugged, in a dream, or as I have read, like if you were on cocaine. I would thank if someone would recognize these symptoms and tell with what kind of medication did you feel them as I suspect I have been under covert medication because I refused at first to take those things. It is a long story but I have been medicated wrongly because I have a tumor that causes me weird things and they thought I was depressed just because at first they didn't find anything. Furthermore, a lot of physicians just simply didn't know or explain weird symptoms like extreme photophobia. I swear I had to wear sunglasses even at night because that symptom was unbearable, it literally caused me pain in the day or even when I looked at the floor, strangely that was when I had dilated pupils, really big pupils. I don't do drugs and this happened overnight. The most weird thing is the photophobia, dilated pupils and muscular tightness for me, I was checked neurologically and everything was fine, no head tumors, no eye damage, anything at all. I suspect this covert medication because stubborn psychiatrists wanted to put me on medications and I refused completely because I knew something physical was wrong instead of just a "mental illness", whatever that means. Most of these symptoms suddenly started to dissapear a year and a half ago, gradually, and then I got like a withdrawal syndrome feeling suicidal, like I couldn't go out of bed, suddenly that euphoria went off and nothing would satisfy me at all, it is like a flat emotional response, but then you get depressed and angry, nausea, sweaty.. a total mess. Now, after all that last stir, the last months I have been feeling more like myself and all those symptoms dissapearing but I want to know because all of this seems so suspicious to me. Now, my original physical condition it is not treated so you cannot blame the getting better to a treatment to the physical ailment. Another thing I would want to ask is that if a withdrawal syndrome can last up to many years after you have taken the medications, because I stopped taking those things by myself from one day to another without gradually diminish them and I was wondering if that withdrawal could have lasted by six years (which I don't think so), so my family would have decided to go on covert medication by psychiatrist orders or something or is just something else that I have in my body. I really feel like crap and as if my brain was shook and then you come back to normal life after (and that is something that tumor doesn't do and do not behaves like that).
  8. If you or a loved one had a child with a birth defect after taking antidepressants during pregnancy and you are willing to be interviewed about your experience, PM me and we'll talk. I am a free-lance writer specializing in medical harm.
  9. Hi! I'm Britt777. I joined this site to figure out what is causing me numerous symptoms. Here is my brief story: Took Lexapro for about 3 years or more, came off of it Tried Trintillex and Brintillex, didn't like the way it made me feel Doctor then tried Fluvoxamine 100mg and took that for 7 months. He decided to add Wellbutrin (Bupropion XL 150mg) along with it. A month later I ask to stop Fluvoxamine (Luvox) because I felt like I was experiencing "depersonalization" or pretty much felt like life was not real and was a dream. So, at that appointment he told me to stop the Fluvoxamine and upped my Wellbutrin to 300mg once a day. The first day from this switch I felt great. Then the second day came... had nausea, lightheadedness, dizziness, "brain zaps", increased tinnitus (ringing in the ears), blurry vision, feeling like I could pass out, headaches, head pressure, and crazy fluctuating heart rate. (Today I had a heart rate of 100 and dropped to 70 within 5 minutes without doing anything different.) This is day 7 since the switch. I just want to find out if it's withdrawal symptoms from the Fluvoxamine since he didn't advise me to taper or if it's a reaction to upping the Wellbutrin.
  10. Please help, 2 weeks ago I was prescribed 50mg sertraline for intrusive thoughts, but was not depressed. I took my first one and about 6 hours later I had a very bad reaction I had a fever my blood pressure was high, I had diarrhea and my mind was cray I knew instantly that I had poisoned myself, it wasn't until a week later I read up on serotonin syndrome and realized I experienced all the side effects and still suffer some of them to this day, here are my symptoms I have and have got worse short term Memory loss, agitation, irritability, muscle twitching, shivering, restlessness, sweating(up my neck and scalp mostly), hallucinations derealization/depersonalization, feel disoriented at times, muscle spasms which are painful at times, tingling/prickling sensations in my hands feet chest arms and legs, pressure at the back of my head. I don't get it I was a happy outgoing person until the doctor insisted the tablet would take away intrusive thoughts, not only do I still get them but get even worse! hallucinations! I don't want this Have I got the effects from serotonin syndrome or is this permanent nerve and brain damage? please help I am quite worried and no one wants to listen to me
  11. Hi I am an Orthomolecular Practitioner with extensive experience in the field of mental health, having worked as a clinician for almost 14 years. I have been treated with ANTIDEPRESSANTS MYSELF BEFORE entering the field of mental healthg and I know first hand of the terrible side effects of the medications. Please take note. I am not here to promote my business and I have no self interest to promote. If anyone needs some help and advice, I can give it my best as I am trained professionally. I have no need for reminders either. If you want to learn, look at healyourmind.com.au Good luck
  12. Hello All- Thank you in advance for any tips or support you can provide. I found this forum by accident, and am really struggling. By way of introduction: I am currently 27 years old, and was misdiagnosed in my adolescent years, sending me into a dreadful spiral of reliance on antidepressants and psychoactive drugs for over 10 years. About two years ago I found a wonderful doctor who saw that these were unnecessary and has been guiding me through the process of tapering off of ALL Medication. I have already been able to completely go off of Lamictal (originally 300mg), though it took me a year, and am now in the final stages of tapering off of 100mg Pristiq (has been an ongoing process since this past summer 2015). As of yesterday, I was taking (roughly since they're tough to cut without crumbling) 6 mg of Pristiq and since I cannot really cut them any smaller, today is Day 1 of being at 0 dosage. My doctor was transparent with me in that this may get messy, and it is difficult to predict how anyone will react to this final cut. All along with the cuts I have experienced: extreme anxiety (subsides as my body adjusts) Depersonalization or feeling totally light-headed and "stupid" Headaches Terrible stomach upset I am so fearful of this last cut because I know it will be the worst....yet I know that the positives of my doing so will outweigh whatever costs I need to incur to get there. Does anyone have any insight for folks who have been on high doses of Pristiq for 8+ years and may give me an idea of what to expect? I feel that's the worst part- not knowing what to expect. Many of these posts involve folks who have been on for just a few years, so I am curious as to how the long-term dependence will manifest itself for a case like mine. I am grateful for any words of wisdom you can provide. Thank you!! KimT1717
  13. Hello everyone, I was diagnosed with Anxiety disorder, agoraphobia, claustrophobia, and severe depression, few years ago. I was on Nexito (Escitalopram) and Rivotril (Clonazepam) for almost 3 years. I went off the above medications 4 months ago, i.e., in January 2016. Withdrawals started after a month. My shrink prescribed me with Stablon (Tianeptine) 12.5mg twice a day, to fight the withdrawals. Three weeks into the new drug, and I started experiencing the following symptoms. Head ache/stuffy head Muscle ache Weakness Joint pain Dry mouth Dizziness Anxiety Suicidal Thought Mood swings Loss of taste I immediately contacted my shrink and he put me back to Nexito and Rivotril. Upon asking whether the above symptoms were the side effect of Tianeptine, he simply avoided the question by claiming Tianeptine to a very mild drug. It has been 4 days now, I'm off Tianeptine, and I am feeling much better. Not completely though. My main concern here is the loss of taste. Been 4 days and I cannot taste food at all. Even if I am not eating anything, there is this greasy metallic feel that persists. I went to an ENT yesterday and he concluded it as a reaction to Acidity, and prescribed me with general antacids, lactic acid bacillus capsules, and mouthwash. Since I do not know why it happened and what exactly it is, I am concerned whether I am on the right line of treatment. If anyone out here can help me on this, I'd be grateful. Thank you!
  14. Suziestarshine

    Suziestarshine hello there

    Hello there everyone, recently took the plunge into tapering off of sertraline after our 2 year love affair began to sour. I'm no newbie to anti depressants and have been battling depression for most of my life. I had my first episode when I was 15 which escalated to a suicide attempt at 16. Since then I have had 3 major episodes the last of which began early 2012 but I let it run and then New Year's Day 2013 I experienced the biggest meltdown of my life so far. My GP began my treatment with citalopran but my body was not comfortable with its side effects so this was replaced with sertraline. Dosaged started at 50mg and climbed to 200mg by October 2015. For the most part I have enjoyed my time on sertraline but I now feel more and more side effects manifesting such as rapid weight gain, insomnia and general feeling of weirdness. I really want to kick this drug and began to stop taking them. I had no idea how bad it would be and have had to return to my normal dose. I was experiencing headaches, dizziness, nausea and irratability. I began researching and came across this site and was comforted by the knowledge that I was not the only one. I am now planning to taper myself off sertraline so wish me luck guys.
  15. http://www.madinamerica.com/2016/04/legal-journal-says-antidepressants-can-cause-violence-and-suicide/ Legal Journal Says Antidepressants Can Cause Violence and Suicide April 18, 2016 Antidepressants have been reported to cause a state called “akathisia,” where people feel extremely agitated and restless and may become preoccupied with thoughts of violence. In a new article, to be published in the latest issue of the Journal of Forensic and Legal Medicine, researchers investigate the role of antidepressants in three recent murders. The researchers, a medical specialist and a forensic psychiatrist and pharmacogeneticist, suggest that tests may be done to assess the role of antidepressant toxicity in violent events that may affect legal determinations, potentially even absolving people charged with homicide. The “new generation” antidepressants, SSRIs and SNRIs, appeared in the 1980s but, according to the reviewers, “their adverse effects and clinical trial data have not been fully disclosed.” In 2004, the FDA published a public health advisory warning of worsening depression and suicidality in some patients being treated with antidepressants. In 2007, a Black Box suicide warning was extended from just teenagers and suggested monitoring all patients up to age 24 for anxiety, agitation, panic attacks, hostility, impulsivity, and akathisia. Recent findings show an increased risk for violent crime in young adults taking antidepressants and a groundbreaking reanalysis of the infamous Study 329 on the effects of Paxil on teens found a heightened risk for suicide that was not initially disclosed by the drug companies. The authors report that genetic variations in metabolism affect how individuals react to antidepressants and that research indicated that “ultra-rapid metabolizers” may be at an increased risk for changes in behavior. More at above link...
  16. Hey everyone, I am new to the site. I wanted to share my experience with my successful taper off of the antidepressant Trazodone. I know how awful the withdrawal and discontinuation syndromes can be. I started taking Trazodone after a bad series of panic attacks and constant edgy anxiety, brought on by my brief usage of the drug Wellbutrin. I know this drug has helped people, but for me, it was very bad. It nearly brought me to a psychological breakdown. I was driven to the emergency room, from there I was taken off the drug (after not sleeping for about 4-5 days, I took around 7 Ativan to finally knock me out.) Great time! From there my doctor prescribed to me Trazodone, upon my reporting my constant agitated state, anxiety and repeating panic attacks, and lack of sleep. That drug is ridiculous. I used it for about a year, naively. When I couldn't sleep, I'd up the dosage a bit. And then suffer intense spells of an anxious and panic stricken state for hours on end. At its worse, I was up to over 300mg a night. After a scary and messed up winter on it, I decided that it was not helping anything. My panic attacks were not any better, my anxiety levels off the charts. Doing daily things became a tremendous struggle. I remember shaking in terror trying to open files on my computer. It was messed up and bad. It may have been some of my regular anxiety kicking in as well. I'm not sure if it was fully the effect of the drugs. But here's what I do know. I am completely off the drug. I'm on no drugs. None! I sleep like a baby most nights. I haven't had a panic attack in over a year. My anxiety, when taking the Trazodone, I would say was at a 10 out of 10 (10 obviously being the worst). I'm an anxious person, prone to it, but after tapering off Trazodone and going drug free, I felt it drop to a 0.5. 10 to 0.5! I practically feel normal. I am actually adjusting my new opinion of normal, as I occasionally have very mild bouts of anxiety. But who doesn't? Anyways, I wanted to post this in hopes someone struggling through the taper and the discontinuation would read it and know that there IS light at the end of the tunnel. I remember the wondrously dreadful, distressing, horrific and disturbing things I went through getting off of it. I tapered off rather quickly - 300mg to 0 over about 6 months. I would make big leaps and cut a quarter of the pill off some nights. But I would pay for it later in terrible insomnia, unsettling mental flashes, body twitches, miniature seizure-like jolts. Rapid eye twitching, a deep and utter terror and fright, and long nights of uncontrollable sobbing. A creepy sense of tunnel-vision throughout the day. I went through it all, and luckily for me, only about those 6 months. I know people who go through withdrawal for very long periods of time. But what I wanted to really say is, to endure it. Buckle down and dig in for it. Because it's worth it in the end. It may seem that it will never let up. It may seem there is no end in sight, and that the psychological predicament you feel trapped in will never come to an end. But it will. Steadily. A while later after I was feeling much better, I wrote in my records that it resembled the tapering process to the time it takes to grow your finger nails. Or growing hair. From day to day, things don't really look different. But over a long period of time, you will notice changes. But that's how slow it goes for some, many, unfortunately. Just bite down and give it hell and get through it. The other thing is, trust your brain. It will recover, and reconnect the wires that got crossed. Eventually, and there is going to be a lot of trial and error for it to finally reconnect everything the way it was. But it will. Your brain is constantly renewing itself, reworking, adapting. And with the lack of drugs in my brain, it could finally get to work reconnecting everything in a natural manner, without any interference. I never thought I would be able to do a bunch of things back then. I never thought I would be normal again, go on dates, hang with my friends without losing my mind, work on projects, go out into the world. Seriously. I wrote it all off, I felt hopeless. But just, if you can even find the tiniest sliver of strength to keep going, to push on, to go forward, do it! Things, eventually, they will get better. Much much better. I hope this finds whoever is reading this well, and if you are going through it, to keep fighting it. Things get better, I promise! N
  17. Congress Proposes Research on the Link Between Psychiatric Drugs and Suicide By Chuck Ruby, PhD Featured Blogs March 30, 2016 Congressman David Jolly (FL-13) has recently introduced the Veteran Suicide Prevention Act (H.R. 4640). The bill calls for the VA to study veteran suicides over the past five years and to determine what extent psychiatric drugs are implicated in those suicides. The International Society of Ethical Psychology and Psychiatry (ISEPP) has long been concerned about this issue, and more broadly, how our veterans and military members suffering from the horrors of war and other traumatic experiences are being treated. I sent letters of support to Mr. Jolly’s office, offering ISEPP’s assistance in any way possible. In 2012, ISEPP launched “Operation Speak Up” (OSU) as a response to the alarmingly high suicide rate of veterans. The name signifies our desire to help veterans speak up, rather than being shut up with psychiatric drugs. Although it started as an effort to encourage Congress to consider a non-medical model approach to helping those suffering from trauma, it quickly turned into a grassroots and consumer focused endeavor from the ground up under the leadership of our OSU Director, Mary Vieten, Ph.D., ABPP, U.S. Naval Reserve Commander. Mary has since made great strides in partnering with Melwood, Inc., a non-profit organization dedicated to helping people with disabilities in the greater Washington DC area. Together with Melwood’s support and funding, Mary has created a program called TOHIDU (a Cherokee word meaning “peace of mind, body, and spirit”) as a wonderful alternative to conventional treatment. You can see more about TOHIDU here. Mr. Jolly’s bill will be the first to establish congressional oversight of this alarming problem of using psychiatric drugs shotgun style to quiet the screams of trauma. Despite the increasing concerns of the deleterious effects of psychiatric drugs, they continue to be the mainstay form of treatment within the VA and Defense Department, as they are on the outside. This has to change.The extant research makes it abundantly clear that psychiatric drugs do not correct chemical imbalances. It would be better said that they cause chemical imbalances. They artificially alter brain chemistry in ways that are not clearly understood, and that numb important emotions that signal meaningful issues in our lives. The brain tries to counteract their effect by making changes in how neurotransmitters are used. The person experiences these changes in very agonizing ways, the most worrisome is called “akathisia,” or a state of agitation, restlessness, and a terrible sense of not feeling welcome in one’s own skin. This can lead to unpredictable irritability and violent behavior, including violence toward oneself. To read more on this, see ISEPP’s White Paper. More here: http://www.madinamerica.com/2016/03/congress-proposes-research-on-the-link-between-psychiatric-drugs-and-suicide/ Also on that page is information about how to contact Congress to express your support for this bill. It would be a great idea to also encourage them to investigate the suicide-drug link in other populations too!
  18. If the theory of up-regulated serotonin receptor sites is true as an explanation for depression, this could be a compensatory measure taken by the brain as a result of anxiety, acute stress responses, environmental factors, and even other medications. Seems to me that only non-pharmacological interventions would have any real long-term therapeutic value. Ie. cognitive behavioral therapy, altered thinking process, etc. Any thoughts?
  19. Tashimoto

    TMG (Trimethylglycine)

    The following was posted by a reviewer on the iherb site, offering her responses to the supplement 'Jarrow Formulas, TMG, Trimethyglycine. I take the liberty of posting it here as I was struck by how much benefit she claims to have derived from TMG. I am NOT in any way involved with the sale of this or any other health product. The following testimonial is copied from: http://www.iherb.com/product-reviews/Jarrow-Formulas-TMG-Trimethylglycine-500-mg-120-Tablets/141/?p=1&fr=5 "TMG is a godsend. When I went off antidepressants rather suddenly and was fishing around for something to stop panic attacks and intense bad moods, TMG was the first consistent improvement. Four years later, it is still an indispensable part of my regimen. Perhaps its most important effect is recycling homocysteine into SAMe, which has antidepressant effects. Unchecked homocysteine sensitizes neurons to glutamate toxicity, and probably harms new neurons trying to grow in the hippocampus. Other B-vitamins have also helped me, especially B-2 and B-6 (pyridoxamine), along with fish oil and a non-choline source of uridine (for example magnesium orotate, or triacetyluridine). Some of these will help migraines and focus along with mood. I take 500 to 1000 mg TMG a day; much more may raise cholesterol. Don't mix with acetyl-l-carnitine (and in fact, if you're depressive, I'd advise against acetyl-l-carnitine altogether, thanks to its acetylcholinergic activity). TMG raises carnitine levels itself, and has a mild choline sparing effect. SAMe, by the way, is similar but not so safe; the surge in SAMe levels will create a surge in homocysteine. I tried combining the two, hoping TMG would recycle the homocysteine back SAMe, but I've found TMG on its own most stabilizing and effective."
  20. If you have been harmed by taking Abilify and you are willing to talk about your experiences, I would like to hear from you. I am a free-lance writer specializing in medical harm. I am particularly interested in hearing from anyone who has taken Abilify as an adjunct to antidepressant therapy. Here's links to my latest article in the Canada Free Press: http://canadafreepress.com/index.php/article/68695 http://canadafreepress.com/index.php/article/68708 http://canadafreepress.com/index.php/article/68717 http://canadafreepress.com/index.php/article/68731 If you are interested, you may contact me at patrickhahn@hotmail.com. Patrick D Hahn
  21. Hello everyone. I am glad this place exists. I am currently trying to get off antidepressants and have read many posts on this forum. I would appreciate any advice on my current situation. Here are the basics: March 2001 At age 18, tried marijuana and a high dose of coricidan cough & cold (dextromethorphan) along with alcohol on spring break. Experienced a 'bad trip', freaking out and thinking I was going to die. For the next couple weeks I felt 'off': experienced dissociative feelings, derealization and anxiety (feared I would never feel back to normal) April 2001 Returned to "normal"June 2001 Developed a cold, and upon taking cough medicine, the dissociative feelings returned and I had a panic attack, fearing I had brain damage from taking the drugs which was causing the feelings, along with heart palpitations, minor chest pain and shortness of breath. Went to the ER and they gave me Valium to calm down. The next day the dissociative feelings were still strong. Went to my PCP and he prescribed Paxil 20mg to anxiety. I was also given Xanax to use when the panic feelings were too strong. Along with anxiety symptoms, noticed ringing in the ears after starting Paxil. July 2001 After 6-8 weeks, the dissociative feelings lifted. I felt more normal.August 2001 Although feeling better, still had problems with anxiety and depression at night, so PCP increased Paxil dose to 30mg. After increasing dose, noticed ringing in the ears again, along with mild dizziness/vertigo and dissociative feelings. PCP assured me that these symptoms would subside in a few weeks, and that every negative feeling was a result of the anxiety disorder, while the medicine was making them go away. January 2002 Felt better and under doctor's advice, began tapering from Paxil.February 2002, Ringing in ears got worse after stopping Paxil, as did dissociative feelings and anxiety. Doc prescribed Xanax as needed. (can't remember if I went back on Paxil) December 2002 Overwhelming anxiety, dissociative feelings, depression and panic attacks return. PCP placed me on Prozac 20mg January 2003 Experiencing chest pain and tightness, panic attacks, and extremely high heart rates when exercising. Higher than normal. Anxiety still bad. Doc reassured me I would be fine and this is normal. Taking xanax almost daily to control anxiety Panic attacks became intense, and anxiety was 24/7. No relief. Had to drop out of college and come home. A few weeks later, went to PCP and he took me off Prozac and put me back on Paxil. April 2003 Anxiety, dissociative feelings and panic attacks have gotten better, but still 'on and off'. Feel okay for a week then feel bad for a week. Doc puts me on Paxil CR 50mg. August 2003 Things have improved. Feeling more 'normal.' Able to enjoy things. Went to the doc wanting to lower dose of Paxil. He put me on 12.5mg. October 2003 Switched to Zoloft 200mg because symptoms were returning Felt back to "normal" after a few weeks and able to enjoy things again. January 2005 Lowered dosage to 200mg Zoloft because of weight gain and feelings of fatigueOctober 2005 Dissociative symptoms, anxiety and depression returning. Doc takes me off Zoloft and puts me on Wellbutrin XL 300mg May 2006 Diagnosed with sleep apneaOctober 2006 Symptoms return. Doc places me on Effexor XR 150mg. After a few weeks feel back to "normal". Able to enjoy things again. September 2008 Wanted to get off medication for good. After getting my wisdom teeth out and being on Vicodin, I thought that would be a good time to do it. 2 weeks later, I freaked out and things were AWFUL. Went to the psychiatric ER and immediately restarted Effexor XR. Felt back to "normal" after a few weeks. July 2012 Begin having "episodes" where i feel lightheaded, and a "wave" feeling comes over me. This is accompanied by a significant raise in pulse and blood pressure, extreme panic and anxiety, and dissociative feelings. The episodes last about 10-15 minutes. Often times I vomit. They seem to happen after a lack of sleep, drinking lots of caffeine, or smoking too many cigarettes. Attack becomes so severe I head to the ER. They do tests, all come back negative. Over the next few months, these episodes become more frequent, and anxiety in between these episodes goes up. November 2012 Wake up in the middle night. Extreme fear and panic. Heart RACING. I call 911 and an ambulance has to come pick me up. At ER, all tests are negative and they give me xanax. Go to a psychiatrist who takes me off Effexor XR and puts me on Lexapro. Anxiety gets worse over the next two months. January 2013 Anxiety is worse than it has ever been. It is absolutely unbearable. Like a 24/7 panic attack from the moment I wake up to the moment I go to bed. Psychiatrist puts me back on Effexor XR 150mg, and Klonopin 25mg 3x daily to keep me from freaking out. Things are AWFUL. Like a mental pain and anguish as iff someone is constantly shaking my head. I can't even describe how awful it is. March 2013 Things have not improved. Pdoc raises my dosage to 225mg of EffexorXR. After a few days, things get even WORSE. They are so bad I have to go to the ER and we decide to put me in an inpatient facility. After a couple days in there, I realize there is nothing they can do for me other than mess with medications. I got out of there after a couple days.May 2013 Things have not improved. I decide to enter a partial hospitalization program where I go in for half the day. They do all sorts of classes about mood and attitude and stuff but this is a physical feeling of mental anguish and pain, not a state of mind. They try to convince me it is a state of mind and I can talk my way out of it. Pdoc tries to increase Effexor XR dosage again. Symptoms get even WORSE. My heart rate races up to 150bpm just walking down the street. BP is up to 140/100. (normally 120/80) June 2013 We finally decide to taper me off Effexor XR and back on to Zoloft. It takes about 2 months, but I finally get off Effexor and onto Zoloft. The transfer was HELL. I would have episodes of extreme anxiety and mental pain, and moments where it felt like my brain was being electrically 'charged up.' Every night I went to bed thinking I was going to die in my sleep. I wish there was a way to describe my anguish. Now taking 200mg Zoloft and 25mg Klonopin 3x daily August 2013 Not getting better. Discover benzobuddies.org. Decide I need to get off the Klonopin. It is making me feel drugged and fatigued and unable to live life. And makes me feel like my legs are tingling and asleep all day. Begin my slow taper from Klonopin. Every time I make a cut it SUCKS... November 2013 Finally get off the Klonopin It's rough for a while, but SLOWLY gets better February 2013 At this point I am able to have moments where I'm not thinking about the anxiety/mental pain. This is a step forward. I still have dissociation and derealization, no 'clarity', mental fog, confusion, unable to organize thoughts, feeling ADHD all the time... but slowly improvingApril 2014 Feeling better. No 'painful' anxiety. Only taking 200mg Zoloft daily. Still have dissociation and derealization and anxiety and depression. Can't feel excitement, love, passion, sex drive, etc. I want to get off all medications. I have felt better since getting off effexor and Klonopin, although it has taken so long. I want to get off Zoloft, but I'm not sure when to begin. Because I am not completely better, I am afraid I will get worse if I try to taper now. But I am ALSO afraid that if I do not taper soon, I will get worse and need more medications to help. Advice??? Thank you :-) Edit: I have always been told that all these symptoms are from my anxiety disorder. After years of research, I'm wondering if the original anxiety was from the imbalance, but all these other problems are from the medications. Do I need medications to get better? Or do I need to taper off them to get better. That is my fear :-(
  22. http://www.madinamerica.com/2014/12/strong-placebo-response-forms-even-drug-trials-start/
  23. Hello everyone, I am in graduate school working on my capstone research about trends in prescribing antidepressants. I am inviting you to participate in this anonymous survey. The survey will only be used by me for the purpose of completing my capstone research. I hope that you will take the time to complete the survey. Your response is important and I want to thank you in advance for taking the time to complete the survey. https://www.surveymonkey.com/s/ZS2YFC5
  24. Hi. I'm feloniousgramma, a.k.a wiley. I've been struggling with the bipolar 2 label since 1992 and am wondering about other people's experience with an antidepressant induced hypomanic episode and feelings and thoughts about the bipolar 2 diagnosis.
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