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Jncs posted a topic in Introductions and updatesHi, My husband takes Mirtazapine 15mg every night, along with two psychotic drugs (Trifluoperazine & Olanzapine) for his agitation/yelling and Vortioxetine 10mg (every am) and recently Prozac 20mg. His problem was insomnia but after being put on benzos & antidepressants, it became more complex - one thing leads to another, and he has very bad daytime agitation/constant yelling, memory loss, confusion, low mood, unable to function etc... He has just started Prozac 20mg two weeks ago, to aid with tapering of Mirtazepine. His doctor agreed on 50% cut but he suffers bad withdrawal after 1 week. Previously, he was able to taper off 45mg Mirt to 30mg then to 15mg without much difficulty. So now he is on 25% cut on Mirt. Q: Is this too much considering that he is on Prozac which should help with the tapering as we understand. We are really tired of this journey as his problem was simply Insomnia and it became so much worse after he is put on these potent addictive drugs and we realised that we were trapped! Would really appreciate all your kind advice. Thank you so much!