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  1. I don't know how to put the medication history as a tag, so I guess I'll just put it at the end. Hi everyone! So, I started on 3/21/19 with the Bupropion and Risperidone after being hospitalized for suicidal ideation. I had been resigned for some time because of difficult changes that had been going on in my life socially for the past year, and I was responding angrily and with frustration (internally) until I was pushed to the limit. After hospitalization, I’ve had some transformative thinking around how I interact with people socially, which has led me to an ease with the situation that I hadn’t known before I was hospitalized. I still struggled with social interaction but I am much better and not feeling overwhelmed by my situation as I once was. Although the initial usage of Bupropion and Risperidone I had trouble sleeping the first week, everything seemed fine after that. I had some flare ups of anger, but I was working through it and seeing my psychologist twice a week. In May, my psychiatrist saw that Risperidone was elevating my hormone levels, and he wanted me off of it. I started taking Abilify as a substitute in July. Towards the end of July, the panic-like symptoms I would get from just sitting still was too much for me. I went off of it. He then put me on Latuda. I was on for two days and still had similar effects and I couldn’t sleep. I came off of it, all the while having a lot of withdrawal symptoms- profuse sweating, getting hot, panic. I still couldn’t sleep. I started supplementing with benadryl (at the suggestion of the nurse for withdrawal) then later melatonin. After talking to my psychologist, she suggested that I may have insomnia from the actual Bupropion. Because Risperidone makes some people groggy, what she thought was that the Risperidone masked the activating effect of Bupropion. After I stopped taking the Risperidone, the Bupropion was keeping me awake. She had several clients that had to switch to something else because of the Bupropion keeping them awake. So, I quit cold turkey on the Bupropion, and similarly all the other drugs. I guess my psychiatrist didn’t think I needed to taper from the Risperidone because I had only been on it for 3 months. I thought all was well, but I now have these rushes of anxiety that come over me for around 10-20 minutes at a time. It started after I dropped the Latuda, I believe I was having them even before the Bupropion was dropped but hadn’t noticed a pattern of getting them until the Bupropion was dropped. I get a few (5 or 6) rushes a day. When the rush is over, I'm still usually uneasy for a bit of time after that. I also have some light depression in the mornings, but that has dropped off. The possibility of the anxiety rushes usually stop after 6-7pm at night now (this is a newer development). I go to bed around 10-11pm, so now I can this period the “golden hours” where I feel completely myself and don’t feel like the onset of either a depression tinge or an anxiety rush will happen. So, it’s been technically a little over a month since I CT’d Bupropion and two months since I CT’d the Risperidone. I took both medications from 3/21-7/1 and only Bupropion (and Abilify) from 7/1-8/10. So total I was on medication for about 4 months. What do you think? Will the anxiety rushes fall away? When I am outside of them, I definitely think I can handle this, but when I am getting washes of them, I feel hopeless like it is not going to end. It is unlike anything I ever experienced before taking medication. I would get anxious from various scenarios in the past, but not this random, involuntary rush that occurs for no reason. I look to the writings on here about neuroplasticity (I am 44 years old) and how healing happens every day with building new neural pathways not that I’m off of everything, but I am scared that I am doing this for nothing. Also, I did everything CT, so how does that impact my withdrawal? Thanks for reading, Armorall 3/21/19 started Bupropion XL 150 mg 3/21/19 started Risperidone 2mg 7/7/19 start Abilify half dose 5 mg. discontinue Risperidone 7/9/19 full dose Abilify 10 mg 7/29/19 discontinued Abilify due to panicky side effects 8/2/19 Began Latuda 20 mg 8/5/19 discontinued Latuda due to similar side effects 8/10/19 discontinued Bupropion after realizing it was causing the insomnia From 8/10/19 no drugs whatsoever Withdrawal symptoms coming in and more acute in September
  2. Hey all, 36 year old here – trying to sort out withdrawal effects, med side effects and potential underlying medical issues. Current meds: Bupropion (Wellbutrin) IR – 75mg w/breakfast, 37.5 w/ lunch, 37.5 with dinner (150 mg total) Amphetamine salts (Adderall) – 2.5 mg morning, 2.5 mg afternoon (5 mg total) Caffeine – 100 mg late morning Loratadine (Claritin) – 10 mg w/ breakfast Cefuroxime (antibiotic) – 250 mg morning, 250 mg evening Doxylamine Succinate (OTC sleep aid) – 17.5 mg before bed Current / past health issues: Depression – on and off since about 2000, started Bupropion in 2009 Anxiety – has always been low level, much worse since WD started IBS – dx around 2000 Chronic bladder inflammation (interstitial cystitis) – dx in 2010 Prostatitis – sort of chronic, reason for current antibiotics WD history, short version: Started Bupropion (SR) about 10 years ago. 2018 tapered 50 mg at a time from 300 down to 150. 2/2019 tried to taper from 150 to 100 and stopped due to withdrawal effects. Effects returned 4/2019 despite no dose change. Ended up switching from 150 SR to 150 IR on April 26th, and made large cut to my Adderall and Caffeine doses April 29th. Still recovering from symptoms and trying to stabilize fully. WD history, long version: In 2018, I started tapering the Bupropion down 50 mg at a time (at the advice of my doctor) starting at 300 mg. At the time I was taking the SR formulation. Sept/Oct 2018 - I taped from 200 mg to 150 mg around and got fairly sick for a week in October. Upset stomach, fever, flu-like symptoms. At the time I thought it was just a stomach bug, but after having similar symptoms during WD I’ve been wondering if it was WD. Feb 2019 - Tried to taper from 150 mg to 100 mg and experienced severe dizziness, nausea, fever/chills and sinus symptoms. I went back up to 150 mg after 5 days and felt better within a day or two . April 14th - Picked up my Rx refill, and on April 15th I started to feel lightheaded, dizzy and tired. I got worse over the next few days with headache, congestion, fever/chills, nausea and chest pain. I went to an emergency dentist on 4/21 thinking it might be an abscessed tooth (they said tooth looked fine) and went to urgent care due to pain while urinating. Urine culture was normal, and I tested negative for flu. I went to my PCP on 4/23 with very bad shakes in addition to the other symptoms. At this point, I started wondering if my new refill had somehow been a “bad batch” of the generic meds, so I got an Rx for the same meds from a different manufacturer. I tried that for two days with no improvement. 4/26, I switched from Bupropion SR (taken once a day at this point) to Bupropion IR (taken 3 times a day). The total dose didn’t change. Also had blood work done (CBC w/ diff, comp metabolic panel) – results normal. 4/29, following a morning with very rapid heartbeat, I cut my ADD meds (generic Adderall) from 15 mg to 5 mg. I also cut my daily caffeine from 200 mg to 100 mg. I’d reduced both the ADD meds and the caffeine in the past without any apparent ill effects, so I didn’t think it would have any effect this time around. 5/6 – 5/13 - Symptoms mainly resolved, except for some GI issues. 5/14 I had a rash, fever and shaking. Bad anxiety due to symptoms – went to Urgent Care b/c of rash. Over the next week I also started getting nauseous. 5/22 – Had blood work done again - (CBC w/ diff, comp metabolic panel plus ESR-Wes+CRP to check for inflammation). Also had Urine Analysis. All results normal. 5/29 – 6/6 again felt mostly better save for some lasting GI issues including mild belly pain. 6/6 had fever, chills, fatigue, added dizziness and shakiness over the next few days Most of June: occasional dizziness and stomach pains. 6/17 - Tried to taper from 150 to 131. Reinstated after a few days dizziness and nausea. Early July: Feverish, pains in stomach and chest. Occasional tightness in chest and heart palpitations. Lots of anxiety about symptoms. Started antibiotic July 17th. Current (past few days): some pain in stomach and chest, more frequent heart palpitations. Stomach a bit upset (probably due to antibiotics). I’m seeing a therapist every other week, mostly about anxiety. I’d been planning (hoping) to try tapering the Bupropion again this coming week because I have a few weeks off work, but I’ve having second thoughts since I just started the antibiotic. Also wondering if it would be better to taper the caffeine first, since I should be able to get off that more easily. Glad I found this site, very good to know I’m not the only one 😊
  3. I'm a 27 year old female and I was prescribed to Wellbutrin a year and a half ago. I had never taken any type of psychiatric medication previous to this, and was prescribed to Wellbutrin by a physician that insisted it would help with the depressive symptoms that I was experiencing due to a generalized anxiety disorder (GAD). My primary disorder at the time was GAD, and the only reason that I was experiencing depressive symptoms, is because of the change in my demeanor since becoming constantly worried about the possibility of having an anxiety attack in any social situation. The first time that I went to see a general practitioner about my general anxiety disorder, she immediately wrote me a prescription for Prozac, I took the medication a grand total of three days before having a pretty bad car accident while driving my brother to school. I went back to the doctor and she decided that it would be better if I tried going the antidepressant route. At the time I started Wellbutrin I was in my first semester of graduate school and the effects of Wellbutrin were welcome. I was able to concentrate better than ever before, and was getting all A's in school. It went this way for a little over a year, until 3 months ago when I started seeing a return of my panic attacks. I went back to the doctor and she told me that it sounded like I was building up a resistance to the dosage of medication that I was taking. I was taking a once daily immediate release dosage of 75 mg of Wellbutrin at the time and she decided it would be a good idea to up my dosage to 100 mg of sustained release in order to get me back to a base line. I went home with the medication and thought about what the up dosage meant. I had a lot to consider... I didn't want to be dependent on the medication for the rest of my life. Especially since I was taking an antidepressant medication when I didn't even actually have depression. That day I decided that I was going to quit the medication altogether.. without my doctor’s consent… I had NO IDEA how bad of an idea that would turn out to be. Fast forward to a week and a half after trying to quit wellbutrin cold turkey and I was a COMPLETE DISASTER. I was experiencing suicidal ideation (the first time I’d ever had ANY thoughts like this), MAJOR anhedonia, memory issues and extreme fatigue. I went back to my doctor to get help, because I was scared of what I was going to do. Long story short, she ended up putting me on the Wellbutrin SR 100 mg anyways so that I could level out before I started my taper process. I took the 100 mg SR every day for about 2 weeks and was having some really uncomfortable side effects. So I decided it was time for me to start weening myself off of it. I took the 100 mg SR every other day for two weeks and then every two days for another two weeks, so all in all I tapered off of the medication over a month. I know now that this was WAY too fast, but it’s too late for me to try to go back on it for a slower taper. I’m just wondering if anyone else has a similar story to mine, that can tell me what kind of recovery timeline I’m looking at. I’m experiencing some pretty sever anhedonia and memory/concentration issues that present themselves in waves.
  4. Cigarettes at age 11. Alcohol periodically from age 13 to age 30. Valium episodically from age 18 to age 27. I have been on myriad anti-depressants since 1982 for major depression and generalized anxiety. Imipramine, desyrel, ativan. Off drugs from 1984 till 1995. Started Prozac 1995 till 2014 (did well from 1995 to 2011). Tried Wellbutrin, Cymbalta. Abilify and Trintellix from March 2014 till August 8, 2017 (depression free). Had to withdraw due to cervical dystonia and tremors which still persist. Terrible experience withdrawing from Abilify and Trintellix. Started Wellbutrin 150 mg. and Prozac 10 mg. for one week to help with withdrawal. Then increased Wellbutrin to 300 mg. and experienced ringing in ears; stopped the Wellbutrin and increased Prozac to 20 mg. (10 in A.M.; 10 in P.M.) Now on Prozac 20 mg. per day, occasional Propranolol for tremors (doesn't help). I've read that coming off Abilify can take up to 3 months or more, and it has been 2 months so far. I feel like I've spent (wasted) my entire adult life trying to feel better, first by self-medicating, then by psychiatric medicating. I'm 72 years old. I wonder if there is any hope for me.
  5. Hi there, I have been reading quite a few topics on this website, and would like to see if anyone has suggestions for my situation. I was put on effexor and wellbutrin over 5 years ago. I am not exactly sure of the exact time length I have been on it, and what doses I have tried, but the past few years I have been on 150mg of effexor and 150 mg of wellbutrin. My dr and I decided I can come off the effexor on a tapered schedule. Basically I was tapered from 150 to 75 to 37.5 to nothing in just over a month or there abouts. I didnt keep a track of the dates, which I probably should have. The tapering was ok, I didnt really notice anything happening. Then when I went from 37.5 to nothing, it really hit me. I had all the discussed symptoms and was a mess. I think July 25 was my last day on effexor. In August I think I had two or three good days, and I use the term good loosely here. September I had about 10 good days, October, is only at 8 good days so far. These day are not all in a row, they are very sporadic. I recently started a new job, but it only goes for another month. That has me really stressed out, as I have no savings to fall back on and no job lined up yet. My job I am currently at is good though, it has me outside in the forest, getting lots of exercise and lots of fresh air. Since about October 11, I have been having these crazy crying fits. I just cry, and cry. When I am not crying, I feel ok, but then I start crying hours later. I did go to the walk in clinic, as I cannot get into see my fam dr with my work schedule, and the dr at the walk in suggested I try doubling my wellbutrin either every day, or I could double it up every second day. He said this will still take a month before I start feeling any better, if I do. This morning, out of desperation, I took a second pill and I will continue with this, unless someone has another suggestion... Does anyone have any experience with this? When I have a good day, I still have a tightness in my chest, and I know I am so close to tears, but I am able to ward them off. I find I have to keep myself super busy to not cry, or think, as htinking leads to tears. Today is another rough day, lots of crying already. I do not want to go back on effexor, as my mind has never felt so crisp and clear. I feel unfogged and alert, I do not remember ever feeling like this. Any suggestions would be greatly appreciated.
  6. Today is my birthday and I feel like the best gift ever is finding this forum. I am tapering off of fifteen years of taking Symbyax and bupropion. My psychiatrist seems to have little knowledge about antidepressant withdrawal. I have been on half my usual dose for two months now and I seem to be getting more severe ups and downs. I am so grateful to find other people willing to share their experiences. It gives me strength. I will be monitoring this forum daily as I already feel better knowing you all are here. Thank you.
  7. Hello, and many thanks to this website for being so informative! I only wish that I had known about this site a few years ago (or even a few months ago). Here is why - My 19 year old daughter is, I believe, now going through Bupropion withdrawal. It's hard to know for sure because a virus *could* be partly to blame. Either way, she is too out of it to be her own advocate right now so I am trying to learn as much s possible so that I can best help her. My daughter began taking Bupropion (150mg) in the summer of 2016 for pretty severe depression. In the winter of 2017, Fluvoxamine 100mg was added for OCD. Gabapentin (900mg per day) was added about 9 months ago for nervousness. During this time we moved and had to switch doctors. The new doctor changed her Bupropion to the 150mg XL (extended release) formula about 6 months ago. She was previously taking the 75mg SR version twice per day. It was soon after our move, which corresponded to the new doctor and new Bupropion formula, that my daughter's mental health seemed to take a downturn. In the past 4-5 months in particular she has stayed in bed most days with a low mood. She also started having a tremor in her hands and feelings of nausea off and on. I contacted her PCP in August this year to share my concern and was told it was probably a virus and that she would feel better soon...but she only got worse. A month later the nausea got so bad that she began vomiting all the time. After 5 days of this severe vomiting with no other viral symptoms, the doctors agreed to run tests. We found her ALT to be elevated, and this was concerning in regards to the Bupropion so it was agreed that she would stop taking the Bupropion. Her PCP recommended that she titer by half every 3 days. I thought that I was being cautious by making this a week instead of 3 days. Now, after a month, she is on 18.75mg every other day of the Bupropion SR. Her psychiatrist says she should be off it by now, but I have added this every other day titration at this point and I'm not sure where to go from here. The psychiatrist wants her off the Bupropion so that Lamictal can be started. I'm still not sure about starting another drug at this point! Anyway... To make things even more complicated, we tested her blood for the Epstein Barr Virus (EBV) and her result was borderline (technically they call it "equivocal"). She had mono (which is caused by the EBV) two years ago and got very, very sick then. The fatigue she is experiencing could be related...or not. It's hard to tell. Her PCP feels her fatigue is depression related. The psychiatrist thinks it could have something to do with the EBV. She will be re-tested for EBV next week. And to make things even MORE complicated, her psychiatrist said we should take her off the Gabapentin by reducing one 300mg pill per week. I hired another psychiatrist to oversee psychiatrist number 1 and he said that we could reduce the Gabapentin every 2 weeks but that he did not want to wait longer than that because he wants her to start the Lamictal. We took away one pill almost two weeks ago. Right now my daughter's main symptom is fatigue. She is in bed 90% of the time. She had to drop out of college this semester. She is also super depressed. She was having intense nightmares and sleepless nights these past few months, waking up each morning screaming, but that seems to have gotten a bit better (no waking up screaming the past few weeks). The good news is that her tremor is gone! She does get a little more agitated than normal as well. My daughter is currently taking fish oil (900mg/per meal) and vitamin D3 (5000IU/day) as supplements, and last night she took her first dose of Melatonin 0.3mg. She also takes birth control pills for PCOS. I believe that these pills might be behind her depression but at this point I don't want to jar her system further by removing/changing them. As soon as we can we will address this. My quandaries now are: - How to proceed with Bupropion (currently on 18.75mg every other day - doctor does not want her to reduce more because he wants her to start on Lamictal). - How to proceed with the Gabapentin (doctor says 1 pill per 2 week titer and I worry about this) - Do we give Lamictal a chance? Once she is stabilized, she will begin tapering the Fluvoxamine. We don't think it's really helping her. I now know that this needs to be done at 10% increments each month for years. We will think more about this when the time comes. For now I want to make sure that she is able to get through this Bupropion and Gabapentin withdrawal. If anyone here has any insight or knowledge to share then I would really appreciate it. Thank you, Snek (I chose this name because my daughter loves snakes and this is a cute word she uses for them - she does still smile when I show her pictures of cute snakes so I now love snakes too)
  8. Want2Want2

    Want2Want2: hello

    Hi yall, So much to say, but little time now. Will be back w/more info soon. Glad to be here. Currently struggling with ongoing apathy, indifference, just-not-caring, from initial (and fairly immediate) introduction of Zoloft in 2013. It has persisted since then whether on or off medication, although it IS dose dependent w/Prozac. Reading this forum has been instrumental in my previous tapering but only now have I created an account. So thanks to all, especially Altostrata. I know there are much more difficult symptoms, as I've had many of them in the past, but this indifference seems to have completely (permanently?) changed my personality. Preparing to discontinue current doses of 10mg Prozac and 150mg Wellbutrin, beginning in April.
  9. Topic title: Welbutrin use for 10 years have done with tapering but awful things happening almost 2 months still My daughter has been in and out of er spent a week in the mental ward. Since getting off these meds we are at a dead end she is a awful mess. She was put on buspar 2 weeks ago to help cope , any insight any help would be so welcome at this point.
  10. 26/F. Depression/anxiety. History of being somewhat underweight. Family history of severe mood disorders. My brother killed himself about 6 months ago. 2007-2013: Lexapro 10-20 mg. Took this on and off, with 2 cold turkey "quits." I remember it took about 7-8 days of sleeping and withdrawal symptoms both times. Luckily this time around, my SSRI has a much longer half-life, and wellbutrin has been pretty tame so far in terms of withdrawl side effects. 2015: Moved out of state by myself. Lived alone. Started seeing psychiatrist regularly. After trying: citalopram, sertraline, and the SR version of bupropion, my stable prescription has been 150 mg bupropion XL (wellbutrin) and 30 mg fluoxetine (prozac) in the morning everyday. Wellbutrin was my "Godsend." I was crying for 12 hours a day for no reason. Wellbutrin made it possible to get out of bed. 2017: Moved back with family. They're feeding me and taking care of me. I'm trying a taper because of side effects. There are so many "mild" ones that it's difficult to even identify them anymore - I've accepted them as just "normal". The dizziness, the foggy brain, the random "blank" moments when I forget what I'm saying mid-sentence. GI symptoms... Etc. I stopped the wellbutrin earlier this week. According to this website: https://www.health.harvard.edu/diseases-and-conditions/going-off-antidepressants it should be out my system 99% by now. Keeping the prozac consistent. I have a ~10 or so pills of .025 generic xanax that I'm keeping for panic attack emergencies or acute withdrawal symptoms. I'm taking 3 capsules of 10mg each. I might try dropping one whole capsule for a week and see how I do. I will be of work for a few weeks so it will be a good time to experiment. I'm trying to add lifestyles changes that will help me manage depression. Here is what I am trying right now, in approximate order of perceived efficacy: 1. exercise: 3-5 days a week, trying to get 150min of moderate cardio and 2 days of full body strength (per CDC recommendation). Has helped with mood, self-esteem, dramatically improved sleep quality and appetite. 2. meditation: using an app for this. started with 3 minutes, went up to 10. Haven't done it the last few days, will start again tonight. 3. sleeping hygiene - work in progress. 4. diet: avoiding processed foods and junk foods, eating 3 good meals a day, lots of water. I have been experiencing huge pangs of thirst since stopping wellbutrin. I'm taking a few supplements (curcumin, probiotics, among others) but I don't know if that's doing anything. I'm interested in "gut health" - apparently there's a huge connection between the gut and the brain, eh? Trying to take care of it. I'm also reading some books. Currently reading Upward Spiral. Has anyone read it? Here's the description: "Depression can feel like a downward spiral, pulling you into a vortex of sadness, fatigue, and apathy. In The Upward Spiral, neuroscientist Alex Korb demystifies the intricate brain processes that cause depression and offers a practical and effective approach to getting better. Based on the latest research in neuroscience, this book provides dozens of straightforward tips you can do every day to rewire your brain and create an upward spiral towards a happier, healthier life." Here's to managing symptoms... of the meds, withdrawal symptoms, and depression.
  11. All of my symptoms in bolded, for ease of quick scanning for relevance by anyone interested. I have ended up on this website after lots and lots of google research to pin down the cause of my incessant symptoms of a low-grade migraine headache and constant nausea that I have been experiencing for 10 days straight now. My Migraine History: I have been getting migraines fairly regularly (about 2 or 3 each month) since middle school. but they are pretty mild, as migraines go. About 25% of the time, one will be preceded by an aura that is a lightening-shaped blind spot or blurry vision and then the headache will be very severe. And occasionally, one will be accompanied by severe nausea. But normally, my migraines are just quite painful headaches accompanied by heightened sensitivity to light, sounds, and smells. With ibuprofen and extra sleep, they are usually completely gone within 30 hours. During puberty and especially pregnancy, my migraines were more severe in all aspects: nausea, sensory sensitivity, and pain. My Venlafaxine Withdrawal/Discontinuation Symptoms: I did not connect these symptoms to the cessation of Venlafaxine until recently because 1. I did not know that physical symptoms could be related to the cessation of antidepressants. 2. The onset of symptoms did not occur until 5 days after my last half dose of Venlafaxine. 3. I was only on Venlafaxine for 27 days (including a half-dose for the last 7 days). I only made this correlation after several days of googling possible causes, and after including symptoms that I had previously dismissed as insignificant and inconsequential in my internet searches I started experiencing a persistent nausea that did not seem like food poisoning or stomach flu (no stomach cramping, etc.) 14 days ago. There were/are waves when the nausea is worse throughout the day, and a constant malaise otherwise. Unlike the stomach "flu" or food poisoning, there is/was no stomach cramping or urge to vomit. On the 4th day of no relief, I realized that it was just like the nausea I get that sometimes accompanies my migraines. I hadn't equated it with a migraine previously, because there was no headache. I started taking ibuprofen periodically, treating it as if it were a migraine. On about the 5th day, I could feel a headache "trying to set in", which is my usual precursor to an impending migraine (although historically the nausea, if it develops, does not come on until after the headache presents). Since then, I have had no improvement in symptoms. On about day 6, I started googling possible migraine prescriptions and was considering seeing my M.D. the following day, if there was no improvement. I also started googling the combination of all my other mild/querky symptoms to see what else it could possibly be, if not a migraine. These other sporadic symptoms had each seemed inconsequential as they had come and gone here and there, and were easily dismissed. But I was starting to realize they might be related. Muscle Weakness in my biceps that I had noticed when using a steering wheel or when filing through clothing racks while shopping. Crying and/or the feeling that I needed a good cry, without provocation, that felt very similar to PMS (although this was about 10 days after my last menses). Brain Fog in the middle of conversation. I will have to concentrate really hard to remember what the conversation is about, and what I was going to say next. I will forget what my husband told me just minutes ago. Word Recall Difficulty both while texting/typing (spelling) and in conversation (vocabulary). High Pulse Rate of 88pm, which was noted at the medical appointment that I had on the fourth day after my last dose of Venlafaxine, when I felt great. Chills Hot Flashes/Feeling Flushed Sinus Congestion which was present before, but is now much worse, especially at night. Nausea that feels like "Morning" Sickness when there is 0% that I am pregnant. Yes, 0%. At times, I can tell that I will feel better if I eat, and at other times I can tell that eating will make me feel worse. My best time of day is the first 3-4 hours after waking up. Shivers not related to body temperature this one I just experienced last night, and suspect (hope!) is more likely related to my inadverdently taking 2 different antihistamines (diphenhydramine and cetrizine) at the same time! Very pronounced and fast onset of "prune skin" on the soles of my feet, followed by Extreme itchiness on the soles of my feet Another really bizarre symptom that I think might have another cause. ??? I had sprayed the soles of my feet at bedtime with magnesium oil two nights in a row, as I have done in the past when experiencing a severe migraine. I did not bathe or shower until a third night. 5 minutes into my bath, my feet (and only my feet) were EXTREMELY pruny, as if I had been soaking for more than an hour! I have found nothing online indicating that this wierd fluke may be related to the magnesium oil, nor to antidepressant withdrawal/discontinuation. After the bath, my feet were excruciatingly itchy (just the skin, not the nerves) for at least 30 minutes! After much reading on this and other similar forums, I contacted my P.A. that has been assisting in my medication management for the last 3 months. I am going to reintroduce 5 beads of Venlfaxine tonight and see if it makes a difference by the time my afternoon appointment rolls around tomorrow. She is doubtful that any of these symptoms are related to the antidepressant, so I hope this works. I really hope that my experience, along with the litany of literature I will be leaving with her tomorrow, convinces her of this very real and very under-reported issue!
  12. Hi everyone, I am new and super happy to be here. I have been on Prozac 20mg and Wellbutrin XL 300 for twenty five years. I have tried to get off a few times but was not successful. I started to taper in Jan and was down to half doses on May first. The withdraw, specifically anger and self hate became too intense and I went back to old doses two weeks ago. Now I feel like crap. Side effects are harsh and benefit little. I feel like I have let an angry tiger out of the cage and can't get it back in. I am thinking of going back to the half doses and just dealing with the emotional stuff by working out. I started yoga in Jan but maybe harder cardio is the way to get the anger out. Problem is that I am also very tired. I work and come home and go to bed. I journal, go to AA meetings been sober over 15 years. I feel like I am a mess. I am wondering about some of the natural antidepressants like SamE or 5HTP? I just feel like my brain is raw and hurts. Any ideas on how to supplement and sooth my brain? thanks, and I also will stop the taper and work with my doctor but can't see him for another month so that is why I am thinking of going back to the Prozac 10 and Wellbutrin 150 that I have been taking for the past couple of months.
  13. I recently got pregnant and went from 10mg paxil to 5mg in one week and then completely stopped. I then had a miscarriage (about 2 months ago) and am having severe withdrawal symptoms. Would it be safe to go back on a low dose of paxil and try to taper off properly, or is it too late? I am miserable! Thanks in advance. Update as of March 29, 2017: Link to post below
  14. Hi Everyone, I found this forum through the recent New Yorker article and have already found it very helpful. Here's a brief version of my story... I was put on Effexor XR at the age of 15 to treat severe anxiety (I was given a diagnosis of Generalized Anxiety Disorder). At the time I was dealing with teenage hormones and a suicide in the immediate family and having regular panic attacks. As I got closer to 30 I decided I wanted to know what life was like without them, and wondered if being put on them at such a young age had impacted my emotional development. I felt like I had reached a point of relative stability in my life (stopped drinking, good support system). Going off Effexor ended up being a disaster - in hindsight it seems like it was a very fast taper and I reached the point of not being able to get out of bed in the morning due to anxiety. I found a new psychiatrist who put me on Lexapro and Xanax (not every day, to take as needed). I felt very good on Lexapro but I gained about 50 lbs in one year. She then added Wellbutrin into the mix, which didn't make me feel as good. I felt very agitated and had a hard time concentrating. At this time my psychiatrist was fixated on my weight and wanted to increase my Wellbutrin while going down on the Lexapro. We'd have arguments about it where I tried to explain how bad the Wellbutrin made me feel, despite the weight loss benefit. Eventually we parted ways and I am now trying to taper off everything for the first time in my adult life with another psychiatrist. I'm currently 4 weeks off Lexapro and on 100 mg of Wellbutrin. I am in therapy weekly in addition to seeing my psychiatrist monthly. I started taking fish oil after reading this site and am trying to integrate some dietary changes in addition to my regular yoga/meditation practice. I struggle with feeling a lack of agency over my own life and feeling helpless. The constant focus on and discussion of my weight over the past few years has also not been great. On my bad days I have feelings of hopelessness and despair and occasional depersonalization. I don't have an expectation that I will feel great all of the time, I just want to feel some level of control over my mental and emotional state. Reading this site helps me because I feel like I am not alone. You guys have already helped me so I want to say thank you and I hope I can learn more - the concept of windows and waves is really useful. Today is a window which is why I'm able to write this - I've had two good days and that feels really encouraging. In the meantime if there are any suggestions for additional supplements or lifestyle changes I'm all ears!
  15. rhanch

    finding my way

    I've been taking antidepressants, nearly as long as they've been around. Following a psychotic break - clinical depression, which might have been predicted, given the circumstances and looking back at it. I was first prescribed Sinequan by my family GP - a tricyclic drug considered at the time the latest medical miracle. It seemed to work and brought me back to earth, though it may have been just as much a result of a change in circumstances. The thing is, the fact that it seemed to work against the closest thing to absolute hell I could have possibly imagined created the fear that going off it would return me to the same state. So I continued taking it, in larger or much lesser amounts but continuously, through the coming decades. The ssri's came on the market and books were written declaring the latest and most important, culturally transforming chemotherapeutic drugs. I threw my hat in the ring and decided to try Prozac. Was quickly thrown into some sort of dissociative/ serotonin syndrome state and quickly retrieved the hat. My GP eventually retired and had to shift to a psychiatrist to ensure my supply of antidepressants. He more or less turned me into his psychiatric guinea pig. "I believe it may be prudent to throw Abilify into the mix at this point." "Well, you're the expert." Or so he figured. The upshot: I'm currently taking 150 mg Buproprion,150 mg Venlafaxine 50 mg Trazadone & 5-10 mg of Diazepam. Though I haven't taken any Venlafaxine for a few days because I believe it has left me with ED. I have a lot of opinions and insights into what led me to where I am today, but leave that for later. Thank-you for your attention and/or feedback.
  16. Hello Everyone, Has anyone had a successful taper from wellbutrin 300XL? I would appreciate any feedback. The doctor wants me to drop to 250 mg, but I'm kind of scared because that's more than a 10% drop. He says that wellbutrin is easy to withdraw from. (?????) Thanks so much!
  17. Am frightened Weened MYSELF off zyprexa and buproprion SIX WEEKS ago and am very sick. 24 7 headache for SIX weeks and NO SLEEP. Anxiety and manía off the charts. I keep thinking with each day i will get better. Will I? Dont want to go back on. Feel like getting worse. No money. No Insurance. Not working. Huge medical debt. Can not go back to Dr who did this to me. Will this get better? On both 4 months. On MANY MORE through the years. In January stopped 15yr opiods and 10yr benzos use. Is this zyprexa? 5.5 months off benzos and opiods is it that? Taking 10mg zolpidem to try and escape hell on earth and this headache NOT WORKING. Afraid to stop that too. Frightened to be in hospital or back on meds trying to get off of. SIX WEEKS! Can anyone tell me this will get better? Please? Living a nightmare.
  18. I have been on Wellbutrin for the last 10 years. I am currently on 300 mg of bupropion extended release. This will be my third attempt to taper off successfully. This time I have prepped my body and created a conducive environment to successfully taper off. I've followed the pre-taper protocol of a few holistic psychiatrists, mainly Dr. Kelly Brogan. Can anyone who has successfully tapered off Wellbutrin recommend a tapering schedule? Also, did you have the drug compounded into a liquid to taper or just taper down using the tablets? The compounding pharmacy said that they couldn't create a compounded version of the extended release of the Wellbutrin; it would just be immediate release. Is this true?
  19. Hi I have been on Wellbutrin 150 XL for 4 years. I tried to cold turkey 2 years ago, and spent 5 days unable to get out of bed. Due to loss of insurance, and really wanting to be off meds, I am tapering again. I received Wellbutrin 75mg IR (immediate release). I was going to start off with a slow taper, however the IR pills have been a roller coaster. When I first take the pill I am irritable and agitated for about 3 hours. And then I become lethargic and tired until my next dose. Due to these ups and downs I had to reduce the dosage pretty quickly. I take 3 doses a day. 3/8 in the morning, 3/8 at lunch, and 1/4 in the evening. For a total of 75 mg a day. I started tapering 2 weeks ago, and finally now feel pretty stable. Honestly, the best time for me is when i first wake up. After I take my first dose I get irritable and agitated. I am planning on doing another reduction tomorrow, and just cannot wait to get off this medicine. I am supplementing with lots of Omega 3s, multivitamin, magnesium and vitamin B. Hope to use this as a journal, documenting my taper. Thank you for reading.
  20. I need help, i have been taking wellbutrin xl 300mg for years and decided to stop cold turkey. It wasnt until after 3 weeks that i started feeling major w/d symptoms. I started taking them again and after 3 days still feeling w/d is this normal?
  21. Hi, guys. My depression started over 15 years ago and I came to the point when I wanted to end up my life, but I've failed. So my journey from one shrink to another began. I've found a good one when my depression was at my worse. I wasn't happy about taking any medications, because the lack of knowledge in psychiatry field (I'm a nurse with some practice in mental facilities as well and I'm not happy about the things I've seen there nor the general thinking from many doctors and other medical stuff. I was also amazed about the lack of knowledge and common sense in them as well). My depression was so bad that I gave up and started using paroxetine. I had some side effects, but withdrawal after few months was much worse. The vertigo and headaches were horrible. And depression was still there in it's best. I was then on few other SSRI and SNRI, none of them worked (fluoxetine, paroxetine, sertraline, escitalopram, tianeptine, venlafaxine, duloxetine), but all of them gave me their own special withdrawal symptoms. At least I knew I wasn't getting sugar pills. In the meantime I also developed panic attacks and severe anxiety. After few years I suggested switcing to bupropion and I was getting better for the first time. I was also taking clonazepam the whole time. I'm feeling fine for over 4 years now but I had to wait with taper due to some other pain related medical condition. I was adviced to start taper clonazepam first (I started taper 4 months ago). What a mistake! I was on 2mg daily and managed to taper to 1mg. Than I suggested my GP and shrink to taper bupropion as well, because it was making taper heavier and none of them were happy with my suggestion. I have my GP on my side now after seeing me in really bad condition a couple of times. Right now I'm taking 0,875mg of clonazepam and 300mg of gabapentin (started a week ago and I'm not on final dose which will be around 600-900mg) because of my pain related condition. It also helps with the withdrawal. I'm well aware that it has a WD of it's own, it's a risk I'm willing to pay considering the current options. I took my last dose of bupropion today and I will give myself a little brake until the end of this month. In january I'll continue to taper clonazepam. I'm not a native english speaker and I appologize for potential weird (ab)use of grammar. I'm sure you've seen worse due to my current taper I'm also not very good with words.
  22. I'm new here. I have been on various SSRIs for 22 years and depressed since I was at least age 12. I went off the latest SSRI, generic Lexapro, because I have gained 30+ pounds over the last few years, needed at least 12 hours per day of sleep and still wasn't happy. I am on the max of Bruproprion. It doesn't seem to have any unwanted side effects. It is supposed to be at least weight neutral when taken without other drugs. The physical withdrawal effects are brain zaps, ringing in the ears, dizziness and nausea. These aren't 24/7 and they may be subsiding. Hard to say. I tapered from 10mg of Lex to 5mg to 5 every other day. I did this starting beginning mid-June. My struggle is that I fear my depression is returning. I feel like I will never be OK. I also don't want to become anti-psych med or anti doctor but I wonder if I wasted years of my life on meds that never worked or if this is the way it will always be.
  23. Hi, Since June 2016, I've taken bupropion XL. 150mg a day for first month, 300 for second month, and then on, 450mg a day until May 2018. As far as I could notice, it did not effect my sexuality either negatively or positively. Around, I believe, the middle-to-end of May this year, I stopped the bupropion pretty much cold turkey because I thought it was just elevating my anxiety and not really helping depression. I did not, at the time, believe I had any negative withdrawal symptoms. It seemed pretty painless. At the beginning of this August, I started taking 150mg of bupropion a day again because I thought - why not - see one more time if a lower dose can help while not increasing your anxiety. Now, though, I'm considering if my noticeable sexual dissatisfaction/lowered libido for the past little while may be connected to my cold turkey discontinuation of bupropion back in May. I'm not 100% sure - I couldn't say exactly how much my current sexual dissatisfaction aligns with the discontinuation, since I hadn't thought to watch for that (I thought bupropion couldn't cause negative sexual side effects.) But based on what I do remember, it seems like a very real possibility, which makes me scared of PSSD (so to speak, since bupropion is not an SSRI.) As I said, I reinstated the bupropion at the beginning of August at 150mg XL a day. In terms of effects, I wonder if for this past week it might be elevating my anxieties again, though It could just be my natural anxiety going into overdrive in reaction to the possibility of PSSD. I don't think there's been a positive effect on my sexuality over the month - though it's seemed a bit more okay these past two days, but that could very well be due to hormones from my period that just arrived, or from abstaining a few days from sexual activity before hand. I don't think it's had a negative effect either - my sexuality has been noticeably not good over the course of this month, but my best guess is that this predates the reinstatement. (But I will admit that I am working off of imperfect memory and not careful tracking.) If it is indeed a symptom of the withdrawal/discontinuation, I am wondering if I should be tapering off (safety and slowly, this time,) or if I should basically continue with the reinstatement in some manner. This site says that reinstatement for withdrawal symptoms is most likely to work within a month and gets more unpredictable the later you go on. It's been 3 to 3.5 months since my discontinuation of 450mg bupropion, and about 1 month now since my 150mg reinstatement. I am worried that, if this was induced by the discontinuation, staying on the medication that caused the problem will potentially cause more long-term damage. But I am also worried that this might be my best opportunity left for reinstatement to work, if it will work, since it's been sub-4 months since the cold turkey discontinuation. What should I do? What is the safest bet here to preserve and heal sexual functioning? Taper off, stay on 150mg longer (and for how much longer?), or increase dosage (and if so, increase it to what, for how long)? Is a reinstatement of this nature likely to work on PSSD symptoms? Is it worth the risk? I do still have some sexual functioning/libido, which I value and can enjoy, even if it's noticeably not what it used to be in the earlier months of this year. I really don't want things to get worse. But of course, I'll be unhappy if they don't ever get better again, either. Is there a wrong choice, here? In honesty: a very large part of me feels sick and anxious at the idea of staying on any longer than necessary, in fear that staying on will potentially cause more long term damage. I *want* to start tapering off safely as soon as possible. And I don't want the possible further elevated anxiety of increasing doses. But I worry I won't heal this possible PSSD naturally, either, and that I'm missing my best chance here by not reinstating further. And not knowing how to proceed - fear of making the wrong choice - is distressing me. Other questions: - Before this, I have never considered myself even remotely sensitive to withdrawal symptoms. I'd cold turkey'd off of, or tapered down fast from, a variety of drugs without any apparent consequence. Even with this most recent CT off the bupropion, the sexual dissatisfaction is the only thing I can think to possibly associate with the discontinuation. How should this information effect my decision, if at all, and does my historical insensitivity to withdrawal symptoms possibly make it more likely that this particular symptom - if it is a withdrawal symptom - will heal naturally? - If this is PSSD, then it's noticeable and I want it fixed, but it's not as severe as I know other people's symptoms are. I do still have some sexual functioning which I can enjoy to a certain extent. Could this also make the chance of natural recovery more likely? - I have not had the chance to discuss the situation fully with my GP yet and tell him my concerns over possible sexual dysfunction caused by discontinuation. I don't know how that information might effect his advice. But, my pharmacist called him and absent these full details, my GP recommends as a process for weaning off bupropion - should I choose to do so - to updose for 2 weeks to 200mg SR (as opposed to 150mg XR I'm on now) and then taper off, I think, by 100mg every two weeks. I already know that's way faster than what this site recommends, but what about the initial up dose to 200mg? Is that a bad/good idea? What is the value in it? I will be seeing my GP to discuss this with him in a week. Thanks.
  24. I've been taking these meds for years. I've been on them mostly for extreme anxiety and depression. What do I need to help with anxiety and depression as I try to get off of them so I can stay off of them. Also, how bad is getting off of fluoxetine, trazodone, wellbutrin compared to getting off of Effexor? Getting off of Effexor was pretty hellish.
  25. I weened off my Welbutrin and almost done weening off my Lexapro. It took almost a year now but with a lot of time staying at the same dose (could've taken a lot shorter amount of time but procrastinated initiating dosage drop). Just wanted to let everyone know that I used 5 htp to help with withdrawal symptoms (mainly light headedness/ brain flashes). and it really helped. I basically stopped the Welbutrin cold turkey with taking about 200 - 300 mg of 5 htp for about a week then lowering the 5 htp dramatically and that really helped. The lexapro is harder but the 5 htp really helps. I don't come on this website often so I you guys are always already talking about 5 htp sorry for the redundancy. I just felt the responsibility to come on here and let everyone know. I was on Lexapro 20 mg and Welbutrin 300 mg and now I'm off. and my sex drive is back and I feel emotionally fine because they were probably a placebo in the first place. good luck
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