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Hello, I think it best to start a history of how I got here. I was also on antidepressants from 1986 to 1989. Was put back on AD’s in 1997. I was functional for years with periods of remission and periods of depression and anxiety. Single mother, worked, raised two girls, etc. I was on sertraline the longest. Over a period of about 4 years I began to slowly lose interest in socializing and doing things and became increasingly anxious and fearful, lost my confidence. Was bumped back and forth from Sert. 100-150mg a few times then stayed at 150. Was able to remain functional.