I've been on the max dose of 200mg per day of Sertraline, an SSRI, since 1990. To begin with it was great. I was working faster, and for longer hours, than was really good for me, physically; but the Dopamine "highs" were so rewarding. Sertraline enabled me to cope - and work even harder. I was getting high on the success I was getting from work and get driving harder and harder.
In 1996 I had a stroke, but returned to work after one year and resumed my "workaholicism". I never equated the SSRI as a possible contributing factor to my stroke, but that possibility has dawned on me re