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Kairos posted a topic in Introductions and updatesHi there, So I've been lurking on here for the past few months, and some of the advice and reassurance I've been getting from reading threads here has really helped turn things around for me after a truly hellish time, so I wanted to lead with thanking you all for that. It's been nice just to not feel alone in all of this. Now, I'll get into some of my history. I started out taking 50 mg of sertraline after a deep depressive episode that I'd been trying and failing to fight through alone for years in about 2016. I took sertraline for a few years, and started having what brief blackouts for a few seconds or less. This was pointed out to me while I was driving with a family member, and ran a light that I hadn't even realised I'd gone past. After the sertraline struggles, I went on 75 mg of venlafaxine, which didn't really help my depression and I started to feel much worse mentally and really struggling with insomnia. In January of 2019, I was prescribed mirtazapine to help these symptoms, I started out on a low dose, and we later upped it to 30 mg. This helped greatly for years. I started sleeping fully, and gradually found some emotional stability, with maybe some minor side-effects, dry mouth, appetite fluctuations, morning grogginess, but that was about it. I still don't know if these two things are related or not, maybe I was just unlucky? However, in June of 2021, I was feeling extremely emotionally happy. But I started to notice tinnitus and a constant feeling of fullness and pain in my ears. I was prescribed a course of antibiotics, but they didn't really help. I later saw an ENT specialist who diagnosed me with eustachian tube dysfunction. A few months later, I started having a feeling of tightness in my chest, trouble breathing, irregular heartbeats, etc. A few ECG tests after a trip to my GP indicated I had pericarditis. After two weeks of ibuprofen, I was supposedly in the clear. And I was, for a little bit, but then I started having more chest pains, tightness, and palpitations again, along with frequent burping, abdominal discomfort, cycling between diarrhoea and severe constipation for several days at a time. I was also having a lot of vision problems (significantly increased floaters, particularly when I look at a bright or white light source, redness, dryness, and photosensitivity). A 72-hour ECG came back mostly clear, and doctors told me I probably had sinus arrhythmia, which is quite normal and usually completely asymptomatic. My blood pressure was normal too. I was put on omeprazole for acid reflux, which helped for a while, but I eventually ran out. Since my gastrointestinal symptoms had settled, I was told to just ride out the chest issues, and that they were likely anxiety. I tried this for a while, and then I started experiencing some other things, sudden leg and arm twitches, tremors, closed-eye hallucinations when sleeping, increased heart palpitations, neck stiffness, and headaches and tenderness at the back of my head. Having researched some of these symptoms to try and figure things out, I spoke to my doctor, who inspected me for signs of infection as a lot of these symptoms lined up, except for the closed-eye hallucinations and tremors. I was told there was nothing wrong. I brought up the potential of having an adverse reaction to the mirtazapine, and he recommended we wait a little longer. I came back a few weeks later with a lot of the same symptoms as well as sharp pain in my kidneys, increased urination at night, extreme anxiety and agitation, and a return of my gastrointestinal issues, whilst still having all of the other issues. I was given a prescription for a lowered dose of mirtazapine to 15 mg and told to taper over the course of a month. By now, it was December. I'd already started to try to improve my diet and improve some of my habits to manage my acid reflux after the pericarditis scare, no coffee (god, I miss it), no alcohol, much better eating habits, and daily exercise through brisk walking/jogging on the treadmill. This helped a little, but while exercising one night, I felt faint after only five minutes, and had severe chest pain, which hadn't happened before. I stopped and called my local hospital's non-emergency number and explained my symptoms and history. I was taken in via ambulance, inspected by paramedics and quickly examined. A brief ECG while I wasn't having palpitations and a blood test returned normal, so I was told something my chest pain and tenderness was "maybe something muscular" and released. I continued to take my lowered dose, and noticed an increase in whatever muscular chest pain I was having, an overall feeling of dullness throughout my body, increased tremors, acid reflux reaching my throat and causing vocal instability, temperature sensitivity, and a lot of brain fog. One night, I stayed up a little later than usual, and noticed that some of the brain fog and dullness eased significantly for a while. I took my dosage before bed and woke up the next day feeling as awful as I had before. I discussed this as a phone appointment with another doctor at my GP surgery, and was advised to stop the mirtazapine immediately without completing the taper. I did so, and felt significantly better for a few days. Then, I guess the withdrawal symptoms must have caught up with me, because a lot of the feelings I'd had returned with a vengeance. Although I stopped having the hallucinations, improved photosensitivity, tremors, full-body dullness, chest tightness, and brain fog, my acid reflux and indigestion got even worse, and I started having nerve pain, symptoms that seem to line up with peripheral neuropathy, constant gurgling in my legs, loss of appetite, extreme anxiety, heart palpitations that felt completely different to the previous ones, and a complete inability to sleep. After a few days of this, I had sharp chest pain after a sudden palpitation that radiated to my left arm. And then I started struggling to breathe. I returned to hospital, was inspected again, returned normal tests (although they had issues drawing blood from my arms), and was sent home again, being told that it was probably indigestion and my breathlessness was a result of a panic attack on the journey to hospital. After discussing my SSRI withdrawal, the hospital advised me to see my GP and restart omeprazole now that I'd been off my mirtazapine for a few days. It's been about a month since I was in the hospital there, and I can say with certainty that things are getting a lot better. I'm no longer having heart palpitations, my flank pain is mostly gone, I haven't had that full-body nerve pain for a while, my appetite's back, and my anxiety's at least manageable now, a lot of the peripheral neuropathy symptoms are improved, I'm sleeping for at least 4 hours on my worst nights, and I think my tinnitus is finally improving. I'm still suffering with increased urination at night, that gurgling sensation in my legs, irregular heartbeats/inconsistent heart rate, bradycardia, constant tiredness, acid reflux/indigestion (I'm on omeprazole again now, but I'm still having some symptoms), as well as some strange pains in my neck and back, mild muscular pains, a nasal drip and occasionally runny nose, an intermittent cough, and most recently a new kind of chest pain around my sternum that only seems to flare up occasionally (possibly costochondritis, or heartburn, but I'm medically undiagnosed at the moment so it's hard to say for sure). That's most of it, at least, there might be a few other minor things I'm forgetting or I don't think are related to withdrawal, but we're gradually unpicking all of these issues. As for things that have helped me, I'm taking a marine magnesium supplement every night that seems to really calm me and help me sleep, and prevent the nerve pain. I've also found that CBD oil or tea seems to help calm my anxiety and nerves during the day, a hot bath does absolute wonders, and the jogging was helping to stabilise my heart rate from some worrying inconsistencies into something manageable as well as calming some symptoms. It seems every week or few days or so, some old symptom goes away and a new one takes its place, and while I absolutely hate the uncertainty and constant change, things do seem to be getting better overall. That being said, I've felt pretty rough today, this new chest pain's been taking the wind out of my sails and got really bad after I used the treadmill yesterday, so I've decided to avoid that strenuous exercise until it settles. I've discussed it with my doctor and we're keeping an eye on it for now. Things still feel quite worrying and challenging, but nowhere near as terrifying as they used to be, for at least a solid month I had no idea what was going on, and I was convinced this all might kill me. The advice I've found here so far has really helped. I just wanted to share my story, provide some advice for anyone else who is still struggling, reassure anyone else out there that it does get better, and see if any more experienced people on this forum had any advice or similar experiences with the issues I'm still having. Thanks for reading and all the advice! Kairos
I am experiencing heart palpitations months after quitting effexor and was looking around to see if anyone could give me some advice or tell me how long it should take for this to stop. It's messing with my head and I need some help. Seeing doctors about it, tests come up clean, had an EKG, they want to put me in a halter monitor. Anyway hi.
MartinvHS posted a topic in Introductions and updatesI am a 60 year old male (with PhD in biochemistry) who has been using Duloxetine for depression for 10 years (60 mg/d). Before that I was on Effexor for 3 years. I also have been hypothyroid (hashimoto) for 30 years, but that is stable (150 micrograms/d T4). Otherwise I am fit and healthy and after retiring from science a few years ago my wife and I now own and operate a flower farm in Australia. I have wanted to stop cymbalta a couple of years ago because I have been feeling well, but I felt I have become highly dependent on it (on the very rare occasion when I forgot a dose in the morning, I could feel it by the evening). I also felt that my GP recommendation to switch to 30 mg/d for a few weeks and then quit was not going to work, so I felt trapped. Then over the last year I developed orthostatic hypotension and irregular heart rhythms and I actually fainted (broke my nose in the fall) and ended up in a cardiac ward in hospital for a few days of observation. I now have a heart monitor implanted but I have not had a repeat incident even though I have episodes of ectopic heart beats. This incident has made me research known side effects of cymbalta more seriously and I have found reference to orthostatic hypotension and irregular heart rhythms in this context. I also have various other annoying ailments which I now wonder if they are side effects from long-term use of cymbalta. Frequent and difficult urination and poor emptying of bladder, excessive sweating, stubborn modest overweight (BMI 26), sleep disturbance, Inability or delayed ability to ejaculate and possibly reduced libido (?). So I decided in the past few weeks that I really need to come off cymbalta and I started seriously researching online how to do it. Soon I came across the tapering method, so I designed the following schedule: My capsules contain 444 micro beads (plus or minus a couple). I had guessed that phasing them out in 150 days might be safe enough and so I planned to reduce the dose by 3 additional beads every day. So -3 beads on day 1, minus 6 on day 2, minus 9 on day 3 etc. down to zero beads on day 150! I was going to do this (laboriously further down the track) by bead counting. A great plan so I thought and I was excited to finally free myself from the cymbalta shackles. But now on day 4 Of my taper I have already come unstuck!! My daily dose is down only 2.5% (1.5 mg) And I already have major withdrawal symptoms: Blistering continuous headaches, cold sweats, weakness, very poor sleep. So back to the drawing board. For now I have gone back to the full 60 mg dose and I will start again in another week or so. So I went back online and after hours of reading came across very useful patient sites. Thanks to those I now realise that I may have to take as long as 2 years to taper off Duloxetine. If only I had known this when I started with AD. A long journey ahead of me but I want to become free of Duloxetine and I hope my heart health issues will improve.
Sandi1988 posted a topic in Introductions and updatesHi new to the group I’m Day 6 off Lexapro after weaning off for 6 weeks from 20mg 15mg 10mg and then 5mg. I’m having bad side effects brain zaps constantly. Anxiety and heart palpitations and so emotional and teary. I’ve started taking omega supplements and b12 and completely cut caffeine and alcohol out. I know I’m early in but would really love any tips or encouragement on how to get through. 🙏