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Christeenie posted a topic in Introductions and updatesHello there I am new to this site and came across some really HELPFUL things and hopefully you guys can help me out with some things. My wife has bipolar II and has been on her cocktail of medicine for about 16 years now. She decided she wants to taper off her medicine and we started with the anti-depressant first which is is her Prozac. She was taking 20 mg of Prozac so we reduced her to 10 mg of Prozac.....HORRIBLE IDEA.. after 5 days of dosing her down to the 10 mg of Prozac she became so irritable, and angry .. like I've never seen before. It is now day 3 of her feeling this way and I'm at a loss... Not sure if i should throw her back on the 20 mg or see if she can ride this out??? I read on here to micro taper off medicine if she cant handle the 10% rule.. Any suggestions? Any help? Any words of wisdom here? She's feeling pretty hopeless but I keep cheering her on since I know this process is going to take a long time and I know she is capable of doing it.