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  1. Hi all. I’m writing on behalf of my husband. Bit of background: 2003 was put on Prozac for 3 months- no adverse reaction and subsequently various doses of venlafaxine which he successfully came off of with no issues. 2013 was switched from Venlafaxine to sertraline. Had ‘activation syndrome’ (extreme anxiety) for 8 weeks (always thought it was him) but went away once body used to drug. August 2021 had been on 25mg for years and thought he would taper over 2 months, successfully came off no issues or problems. january 2022- I was having a C section and he was a bit worried, nothing extreme though, just normal worry and decided to reinstate the Sertraline. Within days, ‘activation syndrome’ was back. He stayed on for 5 weeks and then doctor said ‘come off as you weren’t anxious or depressed to start with’ symptoms of withdrawal started but manageable. He thought after 6 weeks that it wasn’t withdrawal as nhs website said it should have gone after 2 weeks! March 2022- started mirtazapine at 15mg going up to 30mg. Fine for 3 weeks, but then developed activation syndrome and quickly came off. GP advised to go back on to sertraline at a bigger dose- ended up in a and e, so agitated! 3 weeks later, he thought that the mirtazapine might be less activating at a smaller dose, so went back on at 15mg… alas, 3 weeks later, activation syndrome is back! june 5th came off and has been battling severe anxiety, but generally, every other day! I am aware of windows and waves but don’t understand this. One day he’s perfect and the next can’t leave the house! He also started propanalol in June which we feel makes it worse as apparently it blocks seritonin to a degree, but makes anxiety a lot worse if he reduces (or maybe he did too big a jump). NHS have left us to it, no help! Have a private appointment on Monday. Questions are: If he is getting windows this early on, is it a good sign?! The only symptom he has is extreme anxiety/agitation which seems more a reaction to lack of seritonin, thus firing out tons of cortisol? Could he go on a low dose of Prozac to see if that helps? Prozac is the only antidepressant he doesn’t think caused activation syndrome?! is there any experiences with propanalol making matters worse? I think there is a slight improvement in the anxiety but considering it’s only been out of his system for 6 weeks I expect takes a lot longer to build new pathways etc/level out. Thanks for reading. Just want my husband back, it’s destroying me and him!
  2. Hello all, I have been browsing the site and thought i would now try introducing myself and asking the community here for any advice on next steps. About me - My name is Joe, i live in the UK just outside London. My mental health Journey started in February 2020, when i suffered Panic Attacks, followed by severe general anxiety and depression. I was initially given 40mg of Propranolol to help with the Panic Attack episodes. Then 50mg Sertraline for anxiety and depression. These medications helped me stabilize but not improve. i Also had 10 sessions of CBT, which included EMDR Therapy to help my deal with previous Trauma and to disassociate certain situations with Panic Attacks etc. After my dosage was increased twice up to 150mg with little to no effect, i was switched to 20mg of Citalopram in December 2020. I can honestly say Citalopram changed me for the better, i had almost no side effects. I gradually improved to a point where i was enjoying life again, my sex life improved to a point where it was better than i could remember. I had almost no re-occurrence of Panic like symptoms, plus my general anxiety and depression had improved dramatically. I even got Married while taking this mediation (Oct 2021). Previously i was petrified about my Anxiety ruining the day, but i had no problems on the day and couldn't believe how calm and collected i was. Now on to the issue - Because i felt so confident and was in such a good place, On December 1st i dropped to 10mg, and on 1st January i stopped altogether. I soon after experienced Post SSRI Sexual Dis-function (Premature Ejaculation, Loss of Libido and attraction) this quickly expanded to general emotional numbness. I felt disconnected from life, work and my Wife. i was still able to function correctly (go to work etc) but was not enjoying anything like i was before. Around 10 days ago, quickly and suddenly Anxiety/Panic symptoms stated again, i started obsessing about my breathing again (problem i had after my initial panic attacks). I have had to leave work multiple times, i feel overwhelmed and panicky when i feel either trapped or isolated (at work, stuck in traffic, in public). I experience chest pains and stiffness all over. I am also full of regret and negative thoughts, i feel scared and im obsessively worrying about this downward spiral and the impact its having on my health and my relationship with my Wife. I have gone from such a high, to a massive low. I'm seeing a psychiatrist next Tuesday. After much reading on here i feel like i have screwed myself over by trying to do something which i thought was good, stopping the medication!! My initial questions for anybody, although any input at all is appreciated - Given the fact that i tolerated Citalopram very well, Should i start taking it again? in the hope it will help like it did before, and then attempt to taper much much more slowly (my GP has already suggested starting a 10mg dose again). However i am concerned this may compound the problems of PSSD even further. - Any thoughts on whether this may be a relapse of symptoms or simply SSRI withdrawal? - Does anybody have experience with PSSD after stopping Citalopram, and how they dealt with this? Thank you all so much.
  3. Hello I will give a brief summary of what has happened after taking most recent drugs. I am a 21 yr old college student, low-income and person of color who recently had to drop their studies (September) due to what I think is OCD and quit their job (November) due to never before experienced debilitating and frightening symptoms. These began after stopping Luvox 50 mg and Prozac 20 mg. I have never been warned or informed or properly tapered off any psychotropic drug by any psychiatrists I have seen including the one (due to insurance I can only speak with him once a month) who prescribed me the last four recent drugs. I was unfortunately very naive in my decisions surrounding these drugs. For clarity: I was being treated for "depression" and anxiety. Started at age 17. My signature is copied off records of prescription dates. For the most part I did not take pills regularly, I remember last year organizing my room and seeing that I had bottles full of pills I never took. A lot of prescriptions were what the psychiatrists called trial and error, so I was trying pills to see their effects which were miss which made me realize they were making me sick so I stopped. I unfortunately cannot remember which ones I did take consistently prior to this year (2021). Up until summer I was taking propranolol as needed for anxiety/stress (it had been I think ~1 yr more or less since I had taken any drug). During the summer I needed and wanted guidance to cope with anxiety/stress in the form of therapy. Through my insurance I emailed and left calls for many people but did not get responses and was getting discouraged. I was so desperate for relief that I was prescribed buspirone 10 mg, which did initially provide a calming relief. In the beginning of September 2021, I was overwhelmed with work and inability to properly cope with my internal problems which was taking a toll on my studies. *Here is where details become very blurry. I let the current psychiatrist know and he prescribed me Fluvoxamine 50 mg. The first two times I took it in the evening and found that it made me restless, it did not let me sleep. So I switched to taking it in the mornings and cut it in half; it still made me restless and I would be very sleepy during the day. I let the psychiatrist know and he told me to switch to Prozac 20 mg. I took it once it the morning before work and the restlessness was awful, I could not sleep at all. Note: I do remember taking advil pm and even buspirone alongside the fluvoxamine at the same time to abate the restlessness. I ceased all medications and after that and since then I have been experiencing things I have never experienced before. -acute short-term memory loss and other gaps in memory* -frightening confusion* -cognitive problems* -weird thinking and feelings I do not know the words to describe* -vision problems (after-image, visual snow/static, visual distortion, stars in vision)* -loss of personality and identity* -head ache/pain/pressure mostly* (this has been consistent, I remember waking up one day before work in October to a sharp pain only in the right side of my head, then afterwards feeling pressure localized around only the right side of my head/eye, and now a bit of the top of my head) -slipping in and out of consciousness when closing my eyes* -dpdr* -auditory problems (cannot focus on what I'm listening)* -feeling stuck in my head* -intrusive thoughts like never before* -hypnagogia -disorientation -delirium -coordination and balance problems -fear and dread -lack of motivation -bizzare dreams -heart/chest pain -dreadful anxiety for no reason -severe depression/anhedonia (I have never in my life experienced actual depression)* -crying so much There are more but I cannot remember right now. The ones with asterisks are the most concerning for me. Everything came on so suddenly and abruptly and unprecedentedly. I am so afraid that I am developing a more serious mental illness and that I will have to take more drugs which I do not want. I have no support system, my family is busy and other people I know are as well. The psychiatrist doesn't think the drugs did anything. With what strength I have, I was able to schedule a neurologist appointment and will be getting studies done. I feel that I am wasting their time. I think deep down I want this to be something physical that can be cured. Which I know is wishful and doesn't serve me good. I am trying my best to not let my fear get to me but I am constantly reminded of my decisions. I am beyond heartbroken, this is not who I am. I am a spirited and passionate person, I do not know what to do as I wait for answers.
  4. Hello, I'm new to the forum. I've been having a lot of trouble with sleep. This started 2 years ago (Nov. 2011) after my father passed away. I started waking up panicking every time I would start to fall asleep. I was put on 20 mg of Lexapro and 5 mg of Zyprexa. Everything stabilized and was good for 2 months until I developed a rash on my legs. I was told to stop taking the Lexapro immediately. I stayed of of it for 1 1/2 months and wasn't taking any medications. Then I started having fever like symptoms, extreme anxiety and just felt horrible. A psychiatrist introduced Zoloft to me at 50 mg. It drove me out of my mind with anxiety. At this point I was put back on 20 mg of Lexapro and my sleeping problems began again. I was given Xanex to take as needed. Every time I would start to relax and fall asleep I would become shaky, panicky and my heart would race. For the next 3 months I had no natural sleep. I was put on Seraquil, Lithium, Elaville and Trazadone. I had the startling, shaky, panicky heart racing feeling anywhere I tried to sleep except for the spare room. I stayed on 20 mg of Lexapro for quite a while, it was put up to 30 mg but it didn't help so after a few weeks I came back down to 20 mg. Then wellbutrin was introduced, that also made the anxiety terrible so that was discontinued. At this point I decided to wean myself off of the Lexapro dropping 2 1/2 mg every 2 weeks. I got down to 2 1/2 mg in March of 2013 and my anxiety became unbearable. I went back up to 5 mg of Lexapro. I was put on Prozac, stayed on it only a few weeks because of increased anxiety yet again. I remained on the 5 mg of Lexapro until October 2, 2013. At that point I hadn't taken any sleep medication in about a year. I still could only sleep in the spare room without the panicky feeling when I started to fall asleep. 10 mg of Propranolol was added 3 times a day and I dropped from the 5 mg of Lexapro to 2 1/2 mg. The panicky feeling went away when I was relaxing to fall asleep. I decided to drop down to 1 1/8 mg around Nov. 2. Things were getting better, I was able to sleep in my bedroom with my wife again without the panicky feeling when going to sleep. I was feeling great! 6 weeks into that last drop all that changed. My anxiety is horrible, I can't sleep at night without medication leaving me feeling drugged the next day. I'm back to sleeping in the spare room but I even get that startling, panicky, shaky feeling in there now. My heart pounds so hard it makes my hand go numb. Last night was horrible, I had to take 50 mg of Elaville and 50 mg of Trazadone. This is left over from the 3 months of sleeping without natural sleep when they tried so many medications to try to put me to sleep. I'm extremely upset about the progress I feel I've lost with my sleep because now I feel like I'm right back to where I've started. I just don't know what to do about my central nervous system that is triggering the fight or flight response every time I try to sleep. The only thing that works to take away that panicky feeling is xanex but I don't take it that often because I don't want an addiction problem. Thank you in advance for your ideas to help.
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