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  1. Hello! Here’s my psychosis and medication history; so.. i had psychosis which was caused by extremely heavy drinking. i had meds (latest risperdal) for.. 10months and they made me a zombie 😕 i quit risperdal about 4 months ago and i started feeling great little by little, until someday i felt totally back to myself! (Normally i’m talkative, say jokes and laugh alot) uh oh so lately (2weeks) i’ve been feeling myself little bit ”too good” like i’m in a super good mood of love and happiness and i’m super confident! (Nothing euphoric) but *zap* my mood can be killed so easily to super pissed off (like workmate not greeting me) but in these 2 weeks i have learned to drink coffee and smoking cigarettes so.. every day i drink about 5-10cups of coffee (i get usually too energenic) so it (coffe/cig) cause me this kind of energyboosts. I’m not psychically energic, but mentally too energic, my mind is racing like crazy! i’ll try to avoid coffee and cigs and alcohol from now on and i can already see that my mind is alot calmer.. (uh oh coffe/cig withdrawals are going to be hellish!) like i said i’hv been only mentally/emotionally energic (my mood is changing all the time!) but pychically (you know my bodyfunction) i am really LAZY! (Like i normally am) but when i’m alone, i’m super lazy! Even when in my head can make up great ideas and such but i have been reading about mania, i dont waste money or do all the rime something? Like i said, i’m lazy I have read the topic ”dealing with emotional spiral” and thats just the ways my mind is racing! I tried that sleeping habit about listening meditation music and it really helped and i slept within 10minutes! In these 2 weeks i have slept normally only once i didnt sleep at all (drank 10cups of coffee before going to sleep) but i’m still concerned if THIS IS BIPO/MANIA?? 😕
  2. Hello All, This may be slightly long but I think it's worth the read for those on/coming off ADs or with significant others on/coming off of ADs. I've been a member of the Topix discussion that was recently removed since around the middle of last year. Like many, my significant other was prescribed an AD (Effexor in this case) for generalized anxiety. This was in early February. The effects were almost immediate but as I was so unaware of the possibilities with these drugs I did not notice any troubling side effects. She had a lot more energy and her anxiety really was gone, but I did not know to relate this to emotional blunting. This girl was absolutely trustworthy and honest and I know this because we were together all the time and she hid nothing from me. We were inseparable. I came to eventually realize that within the first few days of taking Effexor she began to lose feelings for me, but that "give a ****" factor had already gone away and I was of no concern to her. Within a few months she had full blown mania, she was hyper-sexual and had begun cheating. There was no selection, just whoever would take interest in her. At the same time this started, she told me that she had lost her sex drive. I did some research, found this was a common complaint and decided to give it time. We didn't have sex for many many months, all the while she was sleeping with pretty much anyone who would give her the attention. She started drinking heavily almost immediately. I just had no idea that ADs could do this. Eventually I had a growing suspicion, but I could really find nothing online. It took a lot of very specific Google searches to find what I had suspected, but that was months into it. So fast forward after I found out about the infidelity (which was gut wrenching, agonizing, horrific to say the least - it took the life out of me). I had found the Topix discussion, printed many relevant pages and showed it to her. She almost laughed it off, she would not reply to any specific questions. Like most others, she felt new and more alive. Her friend base had changed, and many of them had been given a very different story than what was really happening. She told a lot of them that she was afraid of me, suddenly cops were showing up because her new partners were calling the cops on me, for absolutely nothing. She would scream and break things and hit me, when she had only had one beer (this stuff is BAD NEWS when mixed with alcohol). At a certain point she had not only thrown me aside, but her entire family as well. They did not understand what was happening, so I began to speak to them. In October her life had spiraled out of control and she decided to begin a taper, but only because everyone insisted and she really had no choice. For what it is worth, her doctors refused to believe me. They actually suggested we up the dose because "it wasn't working". So no help there. The withdrawal was horrible. We tried all the supplements and methods that work for some people, but they had no effect on her. She cut her dose slightly about once a month, the same week she would be softer but then the withdrawal would ramp up quickly. In this period she nearly moved out of the state with her old boss. She was planning on leaving me and I had no clue until I found an email and confronted her. That is when it really hit her. She tapered more quickly (perhaps too quickly) because she just wanted off the stuff. In December she finally quit taking it. She had the very horrible brain zaps, she was insanely moody and I was walking on egg shells non-stop. But I stuck it out. The delayed withdrawal hit around January/February but at this point she knew it was withdrawal. And she absolutely was pissed that she had been given a drug like this. She is more upset now than ever that this can happen. We found out two weeks ago that she is pregnant with my child. We are getting married, and she is dedicated to un-doing these things. We are starting over fresh. It is not easy, but it can happen. The best advice I was given was by btdt on Topix. She said do not hold them to their actions, they do not know what they are doing. My fiance echoes this sentiment now. She is more than angry that she let a GP talk her into taking these meds, and then would not listen when she was a danger to herself. But that is how the stories seem to go. Don't get me wrong, it hurts. And now that we're at the one year mark since this started, there are a lot of triggers that I have to really put in an effort into pushing aside. Simple things - songs, smells, places, weather, tone of voice, etc. I'll be around to answer any questions or comments. I want to help as many as I can.
  3. http://www.ncbi.nlm.nih.gov/pubmed/25470092# J Clin Psychiatry. 2014 Nov;75(11):e1278-83. doi: 10.4088/JCP.14m09046. Correlates of incident bipolar disorder in children and adolescents diagnosed with attention-deficit/hyperactivitydisorder. Jerrell JM1, McIntyre RS, Park YM. Author information AbstractBACKGROUND:The greater severity and chronicity of illness in youths with co-occurring attention-deficit/hyperactivity disorder (ADHD) and bipolar disorder deserve further investigation as to the risk imparted by comorbid conditions and the pharmacotherapies employed. METHOD:A retrospective cohort design was employed, using South Carolina's Medicaid claims dataset covering outpatient and inpatient medical and psychiatric service claims with International Classification of Diseases, Ninth Revision, Clinical Modification diagnoses and medication prescriptions between January 1996 and December 2006 for patients ≤ 17 years of age. RESULTS:The cohort included 22,797 cases diagnosed with ADHD at a mean age of 7.8 years; 1,604 (7.0%) were diagnosed with bipolar disorderat a mean age of 12.2 years. The bipolar disorder group developed conduct disorder (CD)/oppositional defiant disorder (ODD), anxiety disorder, and a substance use disorder later than the ADHD-only group. The odds of a child with ADHD developing bipolar disorder were significantly and positively associated with a comorbid diagnosis of CD/ODD (adjusted odds ratio [aOR] = 4.01), anxiety disorder (aOR = 2.39), or substance use disorder (aOR = 1.88); longer treatment with methylphenidate, mixed amphetamine salts, or atomoxetine (aOR = 1.01); not being African American (aOR = 1.61); and being treated with certain antidepressant medications, most notably fluoxetine (aOR = 2.00), sertraline (aOR = 2.29), bupropion (aOR = 2.22), trazodone (aOR = 2.15), or venlafaxine (aOR = J Clin Psychiatry. 2014 Nov;75(11):e1278-83. doi: 10.4088/JCP.14m09046. Correlates of incident bipolar disorder in children and adolescents diagnosed with attention-deficit/hyperactivitydisorder. Jerrell JM1, McIntyre RS, Park YM. Author information AbstractBACKGROUND:The greater severity and chronicity of illness in youths with co-occurring attention-deficit/hyperactivity disorder (ADHD) and bipolar disorder deserve further investigation as to the risk imparted by comorbid conditions and the pharmacotherapies employed. METHOD:A retrospective cohort design was employed, using South Carolina's Medicaid claims dataset covering outpatient and inpatient medical and psychiatric service claims with International Classification of Diseases, Ninth Revision, Clinical Modification diagnoses and medication prescriptions between January 1996 and December 2006 for patients ≤ 17 years of age. RESULTS:The cohort included 22,797 cases diagnosed with ADHD at a mean age of 7.8 years; 1,604 (7.0%) were diagnosed with bipolar disorderat a mean age of 12.2 years. The bipolar disorder group developed conduct disorder (CD)/oppositional defiant disorder (ODD), anxiety disorder, and a substance use disorder later than the ADHD-only group. The odds of a child with ADHD developing bipolar disorder were significantly and positively associated with a comorbid diagnosis of CD/ODD (adjusted odds ratio [aOR] = 4.01), anxiety disorder (aOR = 2.39), or substance use disorder (aOR = 1.88); longer treatment with methylphenidate, mixed amphetamine salts, or atomoxetine (aOR = 1.01); not being African American (aOR = 1.61); and being treated with certain antidepressant medications, most notably fluoxetine (aOR = 2.00), sertraline (aOR = 2.29), bupropion (aOR = 2.22), trazodone (aOR = 2.15), or venlafaxine (aOR = 2.37) prior to the first diagnosis of mania. Venlafaxine carries the day! Huzzah! CONCLUSIONS: Controlling for pharmacotherapy differences, incident bipolar disorder was more likely in individuals clustering specific patterns of comorbid psychiatric disorders, suggesting that there are different pathways to bipolarity and providing a clinical impetus for prioritizing prevention and preemptive strategies to reduce their hazardous influence. But the drug classes correlate with the disorders--you can't really control for them (calculate their effects away) - WC
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