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  1. Hi everyone, thank you for having me. Im looking for advice about updosing to try to stabilize. Prescribed Mirtazapine February 2018 for insomnia caused by over medication of thyroid. (The thyroid medication caused a severe upset to my nervous system- I had every symptom of hyperthyroidism for weeks, even after I ceased my thyroid meds completely. Going hyperthyroid caused my Cortisol to go high especially at night. It took 6 months for the effects of the over medication of thyroid to wear off. My theory is that the thyroid over medication sensitized my nervous system.) Mirtzapine only worked for a few weeks for sleep. I started at 7.5mg and then after 3 weeks increased to 15mg which again only worked for 3 weeks before the sleep effect wore off. Luckily I found some herbs that helped for sleep but they only worked for a few months. I also increased my dose of Luvox to help with sleep. I took temazapam and zolpidem a few times but was not keen on using them as I’d heard about addiction. Went to psychiatrist he told me to increase mirtzapine to 30mg. I reluctantly did this. Again it only worked for sleep for 3 weeks. But I started getting terrible side effects- crying all the time and internal tremors. So I dropped the dose back down to 15mg. I was only on 30mg for 3 weeks. Withdrawals hit straight away. Worsening at 4 weeks after the drop, and then worsening again at 3 months after the drop. I have not tried to reduce again since this first drop from 30mg-15mg. It has been 8 months of terrible symptoms. DR/DP didn’t hit until the 3rd month after the reduction. I wondered if it would be too risky to updose by 1mg of mirtzapine after this long (8 months since the drop). That would make my dose 16mg. Or should I just try to wait longer? I don’t know what to do. Some symptoms, like nausea, have gone, and the internal vibrations have lessened in intensity. Other strange symptoms seem to have stopped, but the DR/DP and low mood has been happening since the 3rd month. Low mood is perhaps not as severe. S ideations less intense, and anxiety still all over the place. A feeling of being numbed out - in terms of sensations in my body and my skin and since month 3 as well. It seems important to me that one of the side effects when I first started the mirtzapine -and which accompanied each increase briefly- was a level of Derealisation and numbing out sensation. This would pass after a week or two, but I’m assuming this makes sense as to why I have the symptoms I have in withdrawal. Thank you in advance
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