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Hello everyone. I'm CF. Been of psychiatric medication for 4 years, when I was a teen - due to depression and eating disorders. After switching many drugs, by August 2019 (discharged from last hospitalization) I was taking: 100*2mg Lamotrigine, 20*2mg Clotiapine, 25mg Promethazine, 400mg Seroquel XR, 60mg Mirtazapine. In the past: Lustal, Lorivan, Clonazepam & more I don't have documentation of. As of today, I take 100*2mg Lamictal, 400mg Seroquel XR and 45mg Mirtazapine. I am interested in lowering all of those, currently very interested in lowering Seroquel... I was never psychotic or manic. I was given Seroquel, Clotiapine and Promethazine because I was agitated and would self harm constantly. These medications did not change my situation; ECT improved my situation for a month, than went away. Therapy in last year helped a lot. -- My withdrawal history: - Prozac: 20mg (1y) -> 30mg (short) -> 60mg (1y) -> 30mg (1d) -> 0. Side effects: Unknown. Withdrawal: I had no adverse reaction at all, the day I lowered to 30mg I was given Remeron and started having tics. - Clotiapine: 10*3mg (?m) -> 20*3 (4d) -> 20*2 (6m) -> 20mg (2w) -> 0. Side effects: sleepiness (on 20*3). Withdrawal: No symptoms, more energy. - Promethazine: 25mg (6m) -> 0. Side effects: helped with allergies. Withdrawal: no symptoms, allergies still way better than before Promethazine😉 - Lamotrigine: 100mg (?) -> 100*2mg (3m) -> tampering to 0 in 2-3 weeks -> 100*mg (1.6y) Side effects: dry mouth. Withdrawal: Can not recall due to ECT treatment. I believe there were none but not 100% sure. - Mirtazapine: 45mg (1d) -> 60mg (10m) -> 45 (1m). Side effects: 60mg: tics (2h after administration, went away by next morning), sleepiness. The first day I was given Remeron I had tics and couldn't sleep, until I was given a sedative. Became better in the next week. 45mg: sleepiness. Withdrawal: Went from 60mg to 45mg in 1 day. Immediately stopped getting tics, sleep about 1.5h less than on 60mg (7.5h/night now). - Seroquel/Seroquel XR: 20mg (?) - 200mgXR + 20mg (?) -> 300mgXR (2y) -> 400mgXR (2y). Side effects: major weight gain, sleepiness. Withdrawal: not exactly withdrawal, but when I skip a night I have insomnia (2-3h sleep max), and when I skipped two doses - next day was almost normal (5-6h) with no side effects. Slightly sensitive/agitated on day 1 (lack of sleep?). I stopped taking Promethazine and Clotiapine in October-December 2019, Mirtazapine 60->45mg - since March 2020. These are the ones I can remember. I was given other medication before but I can not recall anything. -- My current situation is, my Psychiatrist refuses to let me try and reduce Seroquel XR because of COVID situation. I take XR is cutting it myself is not an option. Don't know what to do, I want to stop taking it, more time = worse withdrawal. I stopped taking 60mg Prozac with no issues (SERT, NET inhibition), Entumine (can not find mechanism of action), Promethazine (D2 and H1). I never had any issues with using brand VS generic. -- I interchangeably use: Lamictal & Lamotrigine; Clotiapine & Entumin/Etumin; Mirtazapine & Remeron.