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  1. Hi everyone,✋I’ve been on a number of different meds in the past due to chronic pain: opiates, benzos, antipsychotics etc. I don’t remember all the names, but I was cold turkeyed at times with severe reactions. The reason I’m on the forum now is that I’ve been tapering off seroquel for many years, it’s the only medication I’m on. I’ve gone from 300mg to 7.5mg and am doing water titration now. I just have a quick question. If I accidentally doubled up on my dose one day does that make the withdrawals worse? I couldn’t remember if I took my dose of 7.5mg because of brain fog a week ago. I couldn’t sleep n thought maybe I didn’t take it as it usually makes me go to sleep, so I took another dose 1am 🌔 as I was so scared of what missing a dose might do. I thought the withdrawals from the last dose were starting the settle, but they’ve ramped up again. I know this happens anyway in withdrawal but I was just wondering if the double dose might have have affected this too? Thank u in advance for your input😊
  2. I cold turkey Seroquel 300mg for 3 weeks then reinstated 100 mg again because the withdrawal was too hard nausea and anxiety really bad. Its been 2 weeks sinceI dropped to 75 mg still have w/d.how long don theses last
  3. Hi all , I am 8 months off reinstated sertraline for a month ( by doc) and Aripropazole. History Its around 4 years back when i passed out my college and not get placed even after making to finals in many interviews .. that i decided to write competitive exam for PG. I had taken coaching but just before exam I came back and found myself unable to recall things. My brain is just like nothing in it. I found myself in despair and stopped studying. This fog is happening all the time since my engineering but I managed to get average marks sometimes and sometimes very good . There is more in back history but I ll get to it later. So, my parents took me to a psychiatrist ( family known) and he put me to Olanzapine and one more thing. He diganosed me bipolar2. I got about 10 pounds on it but its not help . Meanwhile after 4 months, with the help of a relative , I got intern in a company and I moved out with fog to a distant city. TThere in a hospital, they put me on floxetine and Amisulpride for 3 months . Then i moved to a private psychiatrist ... where it starts getting haywire . He stopped fluoxetine and Amisulpride . And put me on Venlafaxine and Seroquel... As i was interning, i get usual heat racing in between job times but my doctor convinced me to stay with it . 4 months and I just started feeling agitated due to stress. It happened that I slapped a senior on abusing me and there I left a job I never happened to get physical in my school or college .. but it happened. Doctor told me to scrap the prescription he wrote of raising Venlafaxine. And he put me paroxetine + Oxcarbazepine. In his words , it is best tolerable and has lesser side effects. I managed to get a job by my own and cracking first time. But this time there is lot of work and culture pressure. Its a startup with full of politics . Boss and his boss .. all keep on putting things. Let office aside, I started feeling some well .. overly casual ... excited .. raged .. Iits about 25 mg Paroxetine and 300/600 mg Oxcarbazepine. I had unusual violent acts .. had hit a school friend .. insomnia.. I decided to leave the paxil by asking the doctor . He said half in a week and then other half a week to off. Thats when it all started , i cannot sleep whole night and with day light i start getting a nap. I left going office with fear of state i was in . I cannot wake and even if I .. i was too tired and angry . Doctor then gave me Mirtazapine which didn't help . I resigned job telling muly boss about all and came back home. It was Nov,2015. I start getting yhese uncontrollable rage that I locked myself in a room. Parents took to a local shrink who put me on Venlafaxine+ Mirtazapine(CRF), lamotrigine, resperidal, Seroquel. The NEXT Day I woke up so fresh .. all calm like 12 yrs back .. i was smiling happy.. but it lasted only 4 hrs .. and i am doomed again . I took those meds 10 days and i decided to go off. Physical Damage. I got brain zaps as sounds with eye movement .. While on Paxil I got severe neck stiffness and movement pains - which came out as Osteophytes. Anger , heart race , memory, fog , chest pains , fatigue ... All I beared for 4 months. Reinstatement after 4 months. Father took me to another psych who put me on Sertraline+ Aripropazole+ Seroquel. I started having increases restless legs than before and the doctor asked me not to go over net. After 2 visits and when he said it wslas Aripropazole for restlessness all time.. and he is cutting it . I stopped all meds . Withdrawals in 8 months. All first symptoms with some new like utter sensitivity in teeth. It is while breathe in most of the teeth . Muscles gone from forearms .. My left hands gone ulnar neuropathy and i got surgery done when no hope lived. Right hand has stiffness too . MAnger I am living with .. I have stopped talking .. I have decided to go sit on my Shop but I was unable to understand the talk . In spite anger biuts and memory makes it difficult to adjust. I keep forgetting people faces .. important talks . So i stopped . Now I am muted all the time with burst inside . Read success stories and play CoC. This is the most I can write now.
  4. Kristine

    Kristine: not alone

    Moderator note: link to Kristine's benzo thread - Kristine: Protracted clonazepam withdrawal? Hello, I am new to this site and would firstly like to extend my gratitude to all the people who have shared their stories and support. I now know I am not alone. My story is long and complex so I will attempt to condense it. I am 43 years old and was introduced to antidepressants 10 years ago after being diagnosed with MDD, GAD and PTSD (l do not feel comfortable with labels) by my psychiatrist. During the first 8 years of treatment multiple antidepressants and other psychotropic medications were prescribed. I will fast forward to October 2015 when I attempted to end my life (I had never been suicidal prior to taking antidepressants). I had to resign from work and was hospitalised for 1 month. At the time I had been taking citalopram for a number of years and had reached the maximum dose. My intuition told me it was not helping. I wanted to stop this medication and my psychiatrist was supportive of this decision. However, it is obvious to me now that she was inexperienced and uneducated with this process. The citalopram was ceased over one week and due to severe anxiety I was commenced on seroquel and diazepam. After leaving hospital I managed to taper off the seroquel and diazepam but became increasingly unwell both mentally and physically. My psychiatrist convinced me that my mental illness had returned and I was commenced on Parnate which was increased in dose over 3 months. Instead of improving my mental and physical ailments worsened and my psychiatrist sort a second opinion. I was hospitalised again in May 2016 under the 'care' of another psychiatrist. This was the beginning of an indescribable hell where I was treated like a human lab rat. Looking back the medications he prescribed were beyond belief and I was the victim of poly pharmacy without adequte professional rational. Unfortunally, like so many others, I was vulnerable and trusted his guidance. He treated me as both an inpatient and out patient over a one year period. Over this time I was prescribed over 14 psychotropic medication some of which were abruptly ceased and crossed over with other medications. If this wasn't enough I was subjected to 15 sessions of unnessaccery ECT. Not surprisingly, I was in a zombified state, unable to function and unable to return to work. My anxiety and depression was not alleviated and I was plagued with tremors, nausea, vomiting, fatigue and migraines. By April 2017 I ceased my appointments with this psychiatrist (he had little belief in withdraw symptoms or side effects of the medication he prescribed - he resorted to blaming me) and returned to my previous psychiatrist. Over the past eight months I have the mammoth task of withdrawing from multiple medications. These include escitalopram (completed reduction), Lithium (competed reduction), clonazepam (partial reduction), bupropion (completed reduction), seroquel (completed reduction), dexamphetamine (partial reduction) and fluoxetine (no reduction). My withdrawal symptoms are horrendous and relentless. My psychiatrist has been unable to advise me along a comfortable path. She appears to be in denial and her support has mostly evaporated. I feel abandoned, alone and frightened. I was forced to seek information independently (for which I am grateful), which continues to be a hideous realisation that for years I was in a constant state of drug withdrawal, side effects and drug interaction. I also feeling very angry about my treatment. I am tapering at the 10% rate now (one medication at a time) but even though I know road ahead will be long and rocky, I feel a sense of empowerment from educating myself. What I am experiencing is common and I am finally breaking free from the clutches of psychiatry.
  5. mngal-want-to-try-again-but-not-sure Hi. I heard this forum will help with other meds besides anti-depressants. I got off of those years ago but probably did myself some damage in the process. I put in a signature so you can see how I got here and where I am. I was so tired from lack of sleep that I was just taking whatever the nurse or doctor said without thinking it through. Now I'm sleeping 5-6 hours and can think well enough to know that I'm in a bad place from these drugs and need to get off. My biggest problem now is sedation/depression. I cannot drive most days. I've lost my job and most of my friends. I used to be much more active but now can't even walk around the block. I also have a lot of anxiety but not sure if it's life circumstances or meds or both. I can't figure out where to start. I'm losing hope that I will ever get better. I do think I got much worse when I started the gabapentin. Actually, I'd say the anxiety got better but the sedation and depression and feeling hopeless got worse. I don't know where to start but I figure I'm not going to ask my doctor for a plan given what happened with the anti-depressant taper he gave me. I wanted to rip my brain out of my head, it was that bad. Don't ever want to experience that again. But can't stay like I am, either.
  6. Hi guys, I’ve been doing some research into histamine since I believe it plays a very key role in the withdrawal process--at least from the medications that I’m on. I will summarise what I’ve found below as well as the potential impact it could have on managing the withdrawal from antipsychotics such as Zyprexa/Seroquel. I searched this forum but couldn’t find any good overview or discussion, so hoping this can help people. Many of the popular antipsychotics such as Olanzapine/Zyprexa and Seroquel/Quetiapine have a very powerful antihistamine effect: only a very small amount of these medications are required to block the H1 Histamine receptor. Zyprexa, for example, has a Ki(nM) of 0.65–4.9 according to Wikipedia, which is incredibly low (the lower the Ki(nM), the smaller the amount of a medication is needed to block a certain receptor). Therefore, withdrawing from histamine-blocking medications (Zyprexa/Seroquel) is associated with increased histamine (as the blocking effect is reduced, histamine levels become elevated). Certain groups of people might have even had a histamine intolerance and/or high histamine before going on psych-drugs (and both histamine intolerance and high histamine--also related to under-methylation--have been linked to psychosis and other psychiatric disorders), so coming off histamine-blocking medications can also exacerbate this pre-existing imbalance, on top of the effect described in the point above. Histamine is a neuromodulator of the adrenals, so elevated histamine can make the adrenals release a lot more adrenaline, instigate ‘fight or flight’ mode in the body and cause severe anxiety. There is also a strong link between histamine and sleep; having high histamine can cause insomnia. Interestingly, histamine levels naturally peak around 3am/4am, which is when many people experience cortisol spikes and unwanted adrenal activity. Sound familiar? All of these symptoms are very common in the withdrawal process, as we unfortunately know. When withdrawing from histamine-blocking medications, you can take steps to bring down histamine levels to help manage the adverse effects mentioned above. I’ve found anecdotal success stories online from the world of integrative medicine; Alice Lee (MD) says: “If you ever want to successfully reduce a medication that blocks histamine receptors, you will need to know how to lower histamine levels.” Lowering histamine levels can be done through a combination of diet and supplementation: 1) Follow a low-histamine diet (google it for more info!) 2) Through supplementation - taking a histamine digester that ‘chews up the histamine in food’ - Alice Lee recommends Histazyme (by Dr. Amy Myers, MD), but I’ve also seen Daosin 50 and other brands which all contain the same ingredient, Daimine Oxidase 3) Supplementation - natural histamine blockers like Allqlear by Integrative Therapeutics, Histaplex A-B by Biotics Research, or Opsin II by DesBio. Avoid xenobiotics for antihistamine support, such as Benadryl, because the body will react with an inflammatory response to a xenobiotic. I know that this kind of integrative approach is generally a dirty word on this forum, but for me it makes too much sense to ignore. Most of this advice comes from Alice Lee, who is a “holistic psychiatrist” who actually went through the withdrawal process herself, and reports impressive success stories weaning her clients off all kinds of medication (APs, ADs), just check the testimonials on her website TL;DR: I’m going to try a low histamine diet (being more careful around the time when I make a cut to my medication), as well as adding some of the anti-histamine supplements and histamine digesters. I will still be tapering using the 10% method. If anyone else has research or real experience in this area, I would be very curious to hear it. I think it is a very under-recognised factor and understanding more could potentially make for a smoother withdrawal. I'm also conscious that it's only one piece in the puzzle, and there are other receptors to tackle too. But for insomniac, Zyprexa-dependent folks like myself, it could be really key. More reading and links to the success stories can be found here: http://www.holisticpsychiatrist.com/viewpoint/2018/6/7/understanding-histamines-connection-to-mental-health and http://www.holisticpsychiatrist.com/medication-withdrawal/ https://beyondmeds.com/2014/07/13/histamine-psych-drugs/ and https://beyondmeds.com/2013/01/07/histamine-intolerance/ from around 33 mins https://www.mthfrsupport.com.au/dao-deficiency-and-histamine-the-unlikely-connection/
  7. In 2014, I was misdiagnosed as being Bipolar and Borderline, and was prescribed Seroquel. Slowly but surely, the dose was increased. In June of 2017, I was admitted to a psych ward, via my therapist. Because I refused any other medication, they chose to increase my Seroquel to 500mg. In August of that year, I met with a new psychiatrist and started to taper off of the medication. From August to December, I tapered down to 200mg. Unfortunately, I was not aware of how fast of a taper that was for my body, and I admitted myself to a psych ward for the fourth time in my life, for what I now know was withdrawal. I was prescribed Prozac and Gabapentin while in the hospital, and my anxiety has not been the same since. In 2016, I did a rapid taper from Diazepam and did not have any withdrawal symptoms. Because of this, along with having no idea how quickly Benzodiazepines could have a negative effect on my body, I chose to go back on the medication due the severity of my anxiety. It would take an incredibly long time to describe everything that I have experienced during my withdrawal and my experience with the system in general, but I can honestly say that it's been one of the hardest things that I have ever had to endure. In total, I have been on 17 different psychotropic medications. It's now April of 2019, and I am down to 50mg of Seroquel, while also trying to taper off of 10mg of Diazepam PRN. To say that it has been a nightmare would be an understatement, both physically and mentally. I can't remember the last time that I wasn't nauseous or filled with anxiety to the point that I can no longer drive. I was excelling in school, but am no longer able to attend due to being debilitated. Along with the nausea, I get brain zaps, my IBS caused from the Seroquel has gotten worse, my entire body is weak and sore, and I'm trying to manage all of the emotions that come with the withdrawal. Last year I was going to an acupuncturist on a weekly basis, but it became too expensive. I am slowly integrating organic and gluten free foods into my diet. I am also about to start taking Chelated Mangnese, Malungay, and Jia Wei Xiap Yao Wan on a daily basis. Does anyone have any prior experience or advice/support on tapering from Seroquel? To anyone that takes the time to read this, I greatly appreciate it. I have also been taking about 60mg of Buspar on daily basis for the past year for anxiety, and it also takes away my nausea to where I can eat again. Are there any supplements/natural remedies to help increase appetite besides exercise? It is incredibly hard for me to do so due to the chronic nausea, however, I would like to be off all psychotropic medications.
  8. Hey, everyone. Here's my introduction (I hope it's not too long): In 1994, at 19, I suffered panic attacks from being bullied in school and having cognitive errors in my thinking (perfectionism, negative self talk, etc.) My parents took me to a psychiatrist who told me I had a "chemical imbalance in my brain," prescribed me 80 mg of Prozac a day, and kicked me out the door. I received no therapy and from that day forward saw myself as a mental health patient. This diagnosis changed the course of my entire life. My Prozac took six weeks to kick in, and it brought with it a slew of side effects: generalized anxiety, hypervigilance (constant surveying the world and my body for signs of panic), stomach cramps, and irritable bowel syndrome. Like the proverbial boiling frog who doesn't notice the raising temperature, the side effects eased in to my life so slowly I thought they were a part of me and my "chemical imbalance." In essence I had a paradoxical reaction to the drug: it amplified my existing struggles but I had no idea my medication was the source. I was never told this was possible, nor was I told about the danger of trying to come off. The side effects made work outside the home, socializing, and dating extremely difficult because I was always afraid of the next wave of anxiety that would send me racing to the washroom. I watched my friends grow up and have careers, partners, and families, while I tried to buoy what was left of my self-esteem with self-help books and different therapists, none of who ever questioned the drug or the dosage. After two years of cognitive behavioral therapy to untwist the errors in my thinking, I tried coming off the drug under the supervision of my doctor in 2006 but the initial reduction of 20 mg every two weeks proved to be far too steep. When I reached zero I had a few days of bliss, then an absolute mental collapse. I developed akathisia and was unable to sit still and paced relentlessly and lost control of my emotions. I felt completely hollow and cried for no reason, all the while suffering from unspeakable anxiety. My parents debated admitting me to a hospital but was told that the doctors would check my medication levels then ask me to leave as there would be nothing they could do. I went to my psychiatrist who misdiagnosed my condition not as withdrawal but as depression and anxiety that the Prozac had been treating. Desperate not to lose my mind, I restarted the drug and lost another ten years to side effects. Two years ago I lowered my dose from 40 mg to 30 mg. Three days later I was to meet friends for dinner for as long as my anxiety would allow. I braced myself during the meal for the inevitable tsunami of mental anguish but what I felt instead was a mere ripple. I was stunned, then perplexed. When I realized what was happening and that the drug had been the cause, I burst into tears. Instead of racing home after the meal as I so often had in the past, my friends and I went to a movie. Over the past few months I've been easing off Prozac at 5 mg every six weeks. My quality of life improves with each reduction. My hypervigilance and anxiety all but vanished at 20 mg. At 15 mg I have become more social than I have ever been, and at 10 mg I feel like myself again - sort of. I've been on 10 mg of Prozac since May 9th, and I'm also on 50 mg of Seroquel. I want to get off the Prozac completely but I'm going to stay at 10 mg for at least three months until I know I'm stable. Though most of my anxiety is gone, I had a panic attack last week. I had an appointment with my psychiatrist yesterday over how much I've missed out on from the medication and cried through the whole thing. Naturally she was concerned that this might be a relapse of depression/anxiety, but I honestly feel better now than I ever did on the higher dose. So...that's me!
  9. Hi folks, First of all I'm new to this site, so feel free to tell me I'm in the wrong area or redirect me.. But here's my story... I currently have what I think is severe anhedonia. Last July, I was a bit depressed (I stress a bit, not majorly).......doctor gave me lexapro 10. After taking this, I vomited on the first night and developed sleep problems. Later in the week, I was given 25 seroquel which apparently would help balance out adverse effects of lexapro.......by the end of the week, I wasn't sleeping and I was suicidal. I subsequently was admitted to hospital. In hospital, I got more and more meds thrown at me and my mid august I was on 125 seroquel, 30 mirtazapine, 20 lexapro, 20 Olanzapine/Zyprexa....My main problem was the medication ripped my stomach apart.....the docs didn't believe me and just gave me more and more meds. I left hospital anyway on the concoction I mentioned.....I spent the following four months on these meds. During those four months, I felt no emotion whatsever, nothing. I felt suicidal, and that I would never recover. I had no desire to do anything. I just stayed in bed until late in the day, even though my sleep did not feel like real sleep. By mid November, i realised that the medication was messing me up, I demanded that I gradually come off everything. On that day, the doctor dropped the mirtazapine, and cut everything else in half. There was a quick taper, maybe too quick, and by christmas eve I was off everything. There were brief windows of emotion during the taper but still 95% anhedonia. Days after I went off everything....I cried for the first time in six months.....days later I laughed for the first time in months... I'm now 6 weeks off everything, I had huge headaches up unitl last week. My stomach started to improve after going off everything and is on the mend. However, I'm still worried about emotions/desires/thoughts etc.....over the last six weeks....I've had maybe 5 occassions where I felt strong positive emotions...and maybe 3 times where I've been sad/angry to the point of proper crying. outside of those 8 occassions, there's still an awful amount of flat feeling, apathy etc... I'm worried and wonder how long or if I will recover at all. Feedback welcome!!
  10. hello all, thx for being here showing the way. my current doses and meds are listed in my signature... i take 68.75mg at night...one 50mg pill and the other a 25 mg pill that i try to "quater" into 6.25mg, not very succesfully! what i need help with now is finding my micro-taper rate and correct schedule, since i suck at math (failed it 2x in high school but they passed me because they pitied me for trying so hard and getting it so wrong!) i had been breaking my 25 mg pills into rough quarters but they no longer break anywhere close to 6.25 mg pieces...so i'm really suffering with the inaccurate pill splitting disaster. i'd love to try the ORA-Pro or actually this one: HUMCO 8916001 Flavor Blend 16 oz, Shape https://www.amazon.com/gp/product/B0773DL1XJ/ref=ox_sc_act_title_1?smid=ATVPDKIKX0DER&psc=1 it's way cheaper looks the same stuff to me...and do a suspension with it and see if i can get a more accurate dose, but after reading all the pages i can find on this site and benzo buddies and others i am still confused... the video on how to make a simple water titration that was for low dose naltrexone as an example showed me how to do the basics measuring 25 ml distilled water and dissolving a 25 mg pill in it for a 1mg medication per 1 ml liquid ratio. i understand that part. and as far as i got it, i would take my nightly 50mg pill of quetiapine whole as a dry pill and then draw out the 6.25mg/6.25 ml of liquid medication from the water solution and dispose of it and then drink/take orally the remainder of the liquid (18.75mg/ml) to make my current total nightly dose of 68.75mg of quetiapine. seems like i could be doing 5 mg/ml cuts instead of 6.25 if i use the solution or a suspension though...and i think i may be going to fast, or at leat the cuts are too abrupt, so i really want to do a microtaper, if someone could do the math part and then maybe i'd have a chance.☺️ where i get messed up is how to mix the ORA-pro/HUMCO suspension liquid with the (mortar and pestle crushed) 25mg pill of quetiapine and then how do i know how much to syringe out of the mixed suspension for my 18.75mg liquid portion dose? or if i did a 20mg/ml would it be easier to measure out? or if i did a microtaper of something closer to a fraction of a mg/ml every few days instead of 6.25mg cut every 4 weeks, maybe that would allow for a smoother taper and less rough withdrawals? i honestly don't even know how to divide 6.25mg by 28 days! i guess you can see why i failed math 2x! anyways... i 'd love to do the 10% (or less) reduction from the last dose as is reccomended, instead of the Ashton method of a "cut and suffer" that i've been trying to emulate...but all of the calculators and spreadsheets just serve to confuse me even more. if anyone here feels my pain and would like to point me to a "micro-taper schedule off of seroquel for dummies" chart or table that shows me exactly what to do for each day of the microtaper ...i don't know what i can offer in return! my eternal gratitude? my kidneys? lol thx again
  11. Hello. I had severe postpartum depression which started at 8 weeks postpartum in December 2017. It was endogenous and melancholic...lots of agitation and anxiety, pacing around, taking on psychotic features. I was put on Seroquel XR 100 mg and 50 mg on seroquel IR both in the evening. Ive managed to come down on the IR by going down 12.5 mg every 2 weeks. I waa fine but once I got to zero (just using the 100 mg XR and no IR) I was hit with nausea, throwing up, loss of energy and anxiety. Also horrendous diarrhea. This feels like the flu its unbearable. What do I do now? How can I wean slowly off the remaining XR when they only come in 50 mg tabs and you cant break them? Scared :(
  12. Hi there, I am hoping to be able to leverage the wisdom of this community to shed some light into my personal situation and help decide possible courses of action. The only people I can speak to in real life about this are my well-meaning family/friends (who think Doctors have all the answers) and my psychiatrist/doctor/psychologist who only respond with medication-related suggestions. Up until this point I have been relatively ill-informed of the pitfalls of withdrawing from psychiatric drugs and I’ve clearly made some big errors along the way. However, my goal (like many I’m sure) is to be drug-free but of course this isn’t something my psychiatrist supports. I am sorry in advance this is such an essay. [And apologies for all bold - my javascript bold function is broken!] About me: I’m a 30 year old British female living in Amsterdam, with a full-time job in Marketing. Where it all began: Just over 5 years ago, at age 25, I experienced a very intense mania with extreme psychosis and was hospitalised. The psychosis was triggered by a melange of stress, diet, lack of sleep and smoking a joint (which I used to do regularly in my teens and 20s with no ill-effects). In the psychiatric ward I was given Olanzapine at 7.5mg dose and gradually over a few weeks, the psychotic symptoms disappeared, and I was discharged. My doctor gave me the loose diagnosis as either Schizophrenia or Bipolar I, but was leaning towards Bipolar--so that’s what I’ve stuck with (but to be honest I’m not sure if it’s correct). After my discharge, I reduced the Olanzapine from 7mg to 5mg and then to 2.5mg over the next few months, and stopped taking Olanzapine completely since the side effects of weight gain and libido loss were not tolerable (with my Doctor’s blessing). For a few months, all was well, until I started getting insomnia, characterised by heart palpitations, feeling of mini panic attacks when trying to fall asleep (and therefore not being able to drift to sleep), and very poor quality sleep when I did manage to sleep. My psych recommended I try taking Seroquel instead, and started me off on 700mg per night. The (Good) Seroquel Years Over the next 4 years, I led a perfectly normal and healthy life--even moved to a new country and changed my job--taking Seroquel with minimal side effects. I managed to reduce the Seroquel from 700mg down to 100mg over 2-3 years, and was feeling better and better the lower the dose (with much less sedation and grogginess the lower the dose). I also switched to a vegan diet & cut down on booze and partying in this time which also helped a lot! Finally, I went from 100mg to 50mg around May 2017, and still felt no adverse affects (only positive improvements). My only concern was the niggling fear that I had become dependent on the Seroquel for sleep. The Disruption - coming off Seroquel cold turkey and switching to Olanzapine In August 2017, completely out of the blue, I suddenly stopped being able to sleep. What then followed was a few months of terrible broken sleep and heavy reliance on Zopiclone (alternating nights) to be able to keep up appearances at work, do my job and maintain normality. My therapist at the time suggested I increase the dose of Seroquel to counter the insomnia, so in October, I moved back up to 100mg Seroquel (occasionally 150mg). This worked a treat for the insomnia, however I suddenly started experiencing very regular involuntary muscle movements (more than a twitch, less than a jerk, around 2x per minute in all different areas of my body), and became very worried this was Tardive Dyskinesia. My Doctor (I didn’t have a psychiatrist at this point) told me I should stop the Seroquel immediately, since this was a serious side effect. I quickly got referred to a psychiatrist, who put me on Olanzapine 5mg instead. The twitching stopped, the sleep was fine, but I hated being on Olanzapine (heavily sedated/low mood/very withdrawn/binge eating/weight gain etc.). Recent struggles with Olanzapine After 2 months on 5mg Olanzapine and its shi*tty side effects, I halved the dose to 2.5mg and stayed on that for 6 weeks with no WD, but annoyingly only a very light reduction in the side effects. Complaining to my psychiatrist, she suggested I try the antipsychotic Abilify (10mg) instead, and told me to switch directly (a hard stop of Olanzapine!). Abilify does not block histamine receptor like Olanzapine and Seroquel, and it did nothing for my insomnia. My sleep started to deteriorate the second I stopped taking Olanzapine, and as soon as it was fully out of my system my insomnia returned with a vengeance - I was not able to sleep without Zopiclone, and even with Zopiclone I would only get 4 hours sleep then get woken up by loud, piercing tinnitus and moderate anxiety. I managed to live like this for only 10 nights, some nights getting no sleep at all, other nights getting less than 4 hours with Zopiclone. Annoyingly all the Olanzapine side effects stopped and I felt great, except for the crippling insomnia which stopped me functioning. I gave in and reluctantly switched back to Olanzapine, which almost brings us to the present moment. Where I'm at Today Ever since going back on the Olanzapine (2.5mg), my sleep problems haven’t really gone away: I can get off to sleep fine, but keep getting woken up by the piercing tinnitus and ‘high energy’ around 4am; often I can’t get back to sleep. I’ve tried increasing the Olanzapine back up to 5mg and that isn’t helping much. Before anyone goes there, my sleep hygeine is pretty good. I've also stopped drinking alcohol completely and have a regular bedtime of 10pm. Now I am starting to panic that not even Olanzapine can help me live a normal life. I am plagued by the fear that I am dependent on Olanzapine to get any sleep and that beneath it lies an incurable insomnia. Regardless, I cannot fathom living my life long-term on Olanzapine and I need an escape plan to give me hope (even if I’m not ready to come off it yet). Where I could use some guidance: >> I am not sure if a lot of what I am experiencing with regards to the insomnia is related to withdrawal, even though I am still on the Olanzapine - is that possible? OR is it more likely that my insomnia is the beginnings of psychosis/schizophrenia and therefore I need antipsychotics to not be psychotic. >> Clearly, I’ve messed up my system somehow with all the medication switching and dose changes (none of the reductions have been that gradual). Is there a good strategy to get me back on track? >> Has anyone had any luck with undergoing biochemical nutrient therapy to help support their taper? This is something I'm looking into. >> (Not really a question) I just find the prospect of tapering and inevitably re-living through insomnia for a sustained period of time incredibly impossible, especially with a full-time job. I just don’t know how anyone does it... I can barely last a week - and I also have the threat of having another psychosis &hospitalisation being induced by insomnia. I realise my situation is not that extreme at the moment, but I am already losing hope and am in a pretty dark place with depressive thoughts about my prospects. I am not sure how I will manage mentally and physically if things get worse (which I suspect they inevitably will). Thank you in advance for reading this far.
  13. naturalborn-successful-story hi i'm new at this forum and i'm brazilian, 20 years old, started effexor when i was 18 for depression, stayed on it for 8 or 10 months, with almost no side effects, after this tried going cold turkey , since then have been dealing with all possible kinds of side effects, i tried reinstatement on january of this year (after 4 months of wd) obviously didn't worked, stayed on them for more 5 months, went to rehab. tapered effexor there and started trazadone and seroquel. now i've been taking 150 mg of trazadone and 25 mg of seroquel, was kind of "ok" so tried to reduce trazadone to 100 mgs, wasn't able to sleep for 3 days, went back on 150 mgs, and added 2 mg of klonopin to use when needed, but since that abruptly quitting of effexor i haven't been the same, dealed with EXTREME anxiety (never was a problem before), SEVERE imsonia, sometimes 5 days without any sleep, chronic pain and numbess and poor coordination on the right side of my body. the left side seems ok, i have no idea why. derealization, poor memory, poor concentration, diahrrea, akastisia, poor stress tolerance, emotional numbess, brain zaps and brain fog, anyway i have been dealing with pretty much all the symtoms you can come up with, pretty hopeless, desesperated, regreted, scared, feeling like it will never be the same. i really want to know what you guys think, is there any hope for me ever being the same again?
  14. 8 years ago I was in a ward voluntarily for three months and then I have been taking Seroquel XR since I have been released . 400mg XR for a period of time and lowered the dose to 350 and then 300. since september 2017 i have reduced the dose to 200, increasing to 300 three times and bouncing back to 200 again. I have stabilized on Seroquel 200mg XR since January 2018 until now. In order to continue the taper I have tried tapering to seroquel 150 XR but I had sleeping disorders. I have asked my psych to change the prescription to 200 IR and I have also got a precription for 25 mg IR pills. I've been told to take 100mg IR at night and 100mg at day. Last night I took the pill and had a good sleep. Today Ive taken the daily dose at around 10PM and I have been very sleepy until 4PM which kinda sucks. I have slept around 3-4 hours during that time. I have thought about decreasing the daily dose soon to 75mg. What are your thoughts about this. How should I continue the tapering?
  15. Admin note: link to benzo forum thread: freespirit123: Lunesta So I've been on Seroqoil nightly for about 3-4 months. I started on 100mg and that only lasted one night. Went to 75mg and that lasted for a couple of weeks then 50mg. Last month I went down to 25mg. And about 4 wks ago I've been on 12-14mg (cutting the 50 in 1/2 then the half in 1/2.) I'm also taking Lunesta 3mg at no hr and about once a week ill need Klonopin.25 bc I have a hard time falling asleep. I've also started Celexa for anxiety during the day. So question and problem! How do I get off this Seroqoil?!? Like is aid I haven't even taking it long to begin with and I've taped to 12-14mg fine but it seems to mess with my sleep when I try and cut that in half. Don't believe I have the EXtended tablet. Help!!! If it messes with my sleep, is it only temp? I don't want to switch this to get hooked on Klonopin bc that's a nasty drug too!
  16. Hello to all you brave souls out there who want psych off drugs. I have been in the mental health system for 10 years, and most of it was because of akathisia related problems that doctors will throw shade at as not happening. The only drug that has allowed me to live akathisia free that I have tried is Seroquel. I haven't been successful at tapering, and started going down by percentages only in the last few years. I have to go 3% because 10% is too fast. I have got nutritional tests (NutrEval and spectra cell) for the past two years that confirm what this article is saying: http://www.optimallivingdynamics.com/blog/7-important-nutrients-depleted-by-psychiatric-drugs-antidepressants-antipsychotics-stimulants-benzodiazepines-induced-guide-vitamins-medications I am going through all my old hospital records to look at what I have forgotten. In 2008 I was put on Celexa and they gave me Inderal for my "presumed" akathisia. I have forgotten most of 2008, but these records are making me mad. They are so arrogant deny the torture that is right in front of them. I respond very badly to these drugs. I will eventually have a list like most of you have that details your med history. If you are tapering off Seroquel or have been tortured by akathisia please message me. If you are going through akathisia right now, please, DON'T LET THEM DRIVE YOU CRAZY!!! It is really happening to you and it has to be stopped. I don't know what else to write right now. I hope you look into basic nutrition as a way to feel better.
  17. Hi, I am currently withdrawing from Seroquel. I have slowly gotten myself off a large cocktail of drugs, the most recent being lithium and diazepam (off lithium since early last year, and diazepam about November last year) I did not realise it would be a bad idea to go off the last 25mg of Seroquel all at once. I thought that would be a small difference. It I only recently that I have realised that I was experiencing withdrawals at all. I have been a bit ill as well and had an operation for stage four endometriosis last year. It is hard to tell what symptoms are from that and what is the withdrawals. Looking at it now, I tapered too fast. I do not think it is a good idea to go back on now. It has been two months, so I guess I have to push through it. I am looking to connect to people in my area, (CAPE TOWN, SOUTH AFRICA), to start a support group, or for someone to talk to. I feel very alone and scared. I think that perhaps if I can talk to others who are experiencing something similar it would help. Thank you for reading this! Tammy
  18. Hello all, I've been reading these forums intensely for the past week as I've been in rough shape, but I found out about SA last August when my meds first pooped-out. Anyways, I thought it was time that I posted and got more involved because it's Hell right now.. So a little background, I was first put on Zoloft in 2006 for social anxiety and depression, which was secondary to the social anxiety IMO. I was started on 50mg and had some slight flushing and palpitation, nothing too severe and completely bearable. Then my psych Dr kept increasing the dosage by 25mg I think about every two weeks until I reached 150mg. I was feeling fine even at 75mg so I don't know why he did that. Anyways I had 0 side effects, sexual or otherwise, and basically got my life back. I got my first girlfriend in college, went clubbing, made friends and got a part-time job. Things I thought were never going to happen in my life when I first started struggling with social anxiety when I was around 17. Then about 8 months in after starting Zoloft, the Dr advised that I taper off and quit because I was doing so well. He had me taper from 150mg to 0 in about 6 weeks or so. After about 2 weeks off Zoloft, the zaps started. They were pretty severe every time I turned my head. Then I got hungry right after I ate so I would eat more. Then I got emotional, to the point that I shed a tear or two while watching a Jet Li movie..I had no clue about withdrawal back then so I just stuck it out and about 3 to 4 weeks after quitting Zoloft, the emotional symptoms hit hard. Crippling depression, anxiety, impending doom, suicidal thoughts, depersonalization. I was bed bound for a few days and then started drinking. So the Dr put me back on Zoloft but I was still a wreck after a week or so, and he added risperidone to no avail, switched me to Paxil and finally Lexapro 10mg and Seroquel 50mg at night which seemed to help after 3 or 4 days. Thinking back, I probably could have stuck with Zoloft after the reinstatement and stuck it out until I stabilized which would have been preferable to adding an anti-psychotic but again I had no clue about withdrawal and I guess neither did the Dr. But the Lexapro and seroquel worked so I stayed on it for about a year before deciding to try quitting again in April of 2008. Went through the same withdrawal after tapering off too quickly (don't remember how fast but probably 10 weeks or less) and reinstated both Lexapro and Seroquel. Decided just to stay on them for life if they keep working because I didn't have any noticeable side effects besides the Seroquel making my nose stuffy but I took it at night and it knocked me out in about an hour so I guess I didn't really care. Fast forward to August of 2017, after the birth of my first child which required some significant lifestyle changes coupled with a stressful/dirty/dangerous work environment, I got the withdrawal symptoms, even though I was on the same dosage. Not a lot of the physical symptoms but very mild zaps 2-3 times/day and just some generalized fatigue which went on for about a 8 weeks, then the sudden crippling emotional symptoms hit. Went to the local Dr (I moved so it was a different Dr) and asked to try Effexor XR after doing some research. Thought I needed something stronger..lol..but was only on it for about 10 days which was hell because by then I also had hot flushes, tinnitus, light sensitivity, and panic attacks. I went back to the Dr and this time switched back to Zoloft with fingers crossed. I went back up to 150mg, but didn't notice much improvement after about 8 weeks so I decided it wasn't working and that I was just going to quit all antidepressants forever. So from October 16 to December 4 2017, I went from 150 mg to 0. Shortly after starting the taper I noticed the Zaps had flared up again but I just brushed it off to the poop-out. I started taking 200 mg sam-e and 250 to 500mg l-theanine in hopes of lessening the withdrawal symptoms, and I did okay with manageable anxiety and little to no depressive symptoms. That is until I decided it was time to stop the sam-e and l-theanine as well. I started skipping sam-e and l-theanine every 3 days, then 2 then every other day and so on until my last dose on the 18th of February 2018. The past week or so I have hit rock bottom again with the emotional symptoms, being homebound and not able to workout which means a lot because I have not missed a single day of lifting weights in the past 3 or so years except the day my child was born. I am now seriously thinking about reinstating either the Zoloft or the sam-e and l-theanine then following the 10% taper method because I will have to move again in about 4 weeks and I'm supposed to go on a month long trip with my family in April, both of which has been stressing me out for some time now. I would rather not if I can because it feels like taking steps back but as I've read multiple times in this forum sometimes it's necessary to go back a few steps to move forward. I'm just scared of the many unknown variables, but it certainly is better than the alternative especially now that I have a wonderful, loving and supportive wife and a lovely baby whom I love very much.
  19. Hello all, just found this site and was looking for some advice on tapering off antipsychotic's. It all started about 11 months ago when I was prescribed saphris for depression by my pdoc to augment pristiq, (I know I should have known better). All was fine until about three months in when I started slowly developing anhedonia, just a complete lack of interest in life, it messed up my endocrine system, and destroyed my short term memory. Having successfully quit seroquel cold turkey in the past I thought saphris would be a breeze.... Boy was I wrong, only managed to make it there days in before the overwhelming anxiety (which I've never had before)and insomnia drove me back onto it. After three failed attempts to taper off(lowest dose is 5mg and couldn't cut sublingual wafers any lower), my pdoc suggested switching to 10mg zyprexa for two weeks then stopping that cold turkey, well that was a mess again, had anxiety from hell and insomnia. Again we tried switching over to seroquel which failed.So now I'm back on zyprexa (with a whole new set of side effects)with the plan of tapering off at a rate of -1.25mg every two weeks, currently I'm down to 7.5mg with moderate anxiety, intermittent insomnia and an insatiable appetite. Just wondering if this is too aggressive a taper, I only have tablets available so I'm just relying on cutting them into quarters. Just want off this pharmaceutical merry go round, feel as though I've been lobotomized.
  20. ADMIN NOTE See ang's Intro topic with her earlier history here ☼ ang: help and confidence needed Hello Altostrata and friends. I now believe I am a success story. I am working, contributing and ENJOYING life again. I am 58, so I am grateful that I can enjoy maybe a few more years of my life. From the amount of drugs I was on, this is a miracle. Took me I would say, many years. Mistakes I made, so, so many, ........then in desperation .......... I found this wonderful lifeline Surviving Antidepressants. The pharma fraud, and psychiatric fraud, and $$$$ made destroying lives on these poisons, I can never forgive. I have not been able to update my own timeline, as I have been so happily busy. I do, however, wish to write my survival story, maybe in 6 months, when I am permanent in my job, and will update with all the things I have done in the last 6 months. Just wanted to say, is hard to revisit this site, remembering how ill and desperate I was. But I will, and I will contribute when I can. Yes, there IS a light at the end of the tunnel, for me the agony waxed and waned for a couple of years. Keep up the fight, never give in. Happy Easter Everyone. I am so hoping you may be able to enjoy, but I know how ill I have been, and family and friends were just too much to cope with. This easter, I cant WAIT to see my grandkids and family. Yes the brain recovers from these poisons. Cheers Ang
  21. Hi everyone, I'm new here. I figured I needed some support through this journey of exploration. I am currently on - Quetiapine/Seroquel 300 mg XR and 25 IR (used to be 300 XR + 100 IR half a year ago, I've been on it, just like the other meds, for more than three years) - Fluoxetine 40 mg - Dexamfetamine 3dd 10 mg I've been on psychotropic meds for 5 or 6 years now (I'm almost 21). I've been on different meds before this combination. The side-effect have taken it's toll on me (No matter how long I sleep, I wake up tired, tachycardia, tremors, constantly out of breath, I feel like an old lady) When I was prescribed my psych meds I was in a very bad place, I was suicidal. However, I feel like most of the reason I was in a bad place was bc I was living at home. Things weren't going well there, and I've had depressed symptoms and an eating disorder that went unnoticed since I was 13. I've had many diagnosis, it started with adjustment disorder, ADHD and asperger, adjustment disorder changed to depression NOS, then came the borderline and eating disorder diagnosis and now I finally have a diagnosis of PTSD and major depression and ADHD (which I agree with). I was originally given the antipsychotic for my "autism and hypersensitivity". anyway the new psychiatrist just coppied that medicine regime and now I figured I'm done with it. It helped me through **** times, but I've been living in a different place for 2 years now and that allowed me to make some process. The whole tapering of Seroquel isn't going easy though. The first 50 mg (in 25mg per 3 months) gave me pretty bad anxiety. I lowered 25 mg again 4 days ago, I've been able to get the anxiety under control with magnesium (3 times a day, 600 mg in total). Beside the mental discontinuation problems, the first 2 days it made my tachycardia go haywire and my tremors go nuts. It was quite funny, but not if that will happen with every 25 mg decrease. 3 and 4 day I was nauseous, vitamin C, camille tea and lemon juice made it slightly better. Anyway, I'm thinking about lowering and eventually quitting (if possible and healthy for me) my other medication. Also, I wonder if it's best to take 200XR, 50 XR and 25 IR or 200 XR 50 IR and 25IR for example. I'm not sure about what's better. Anyway, I'm gonna keep you guys posted. Ask questions if you feel like it, -E
  22. Hi, I've been on Lexapro for a year. My highest dose was 5 mgs. Since Aug. 4th I tapered to 1,25 mg daily. I am feeling terrible. A complete lack of motivation. Unable to get out of bed, wash myself. Stopped working a year and a half ago, am on disability benefit. Lots of anxiety, compulsions and obsessions (hand-washing), terrible insomnia. The additional problem is I'm taking Valium and Ambien. For sleep also Seroquel, a tiny amount (a quarter of 25 mg). Also anti-acne (BC) medication Diane-35. Used to be on Lexapro 10-15 mg in years 2007-2011, switched to Effexor for two years 2012-2013. This caused me terrible acne and post-acne scarring, then to Wellbutrin for 1 month (hot flashes, gaining weight). Then to Prozac for a year. Could normally function, work, but developped severe anxiety, which finally led me to benzos. Zoloft acts on me similarly to Prozac. Severe anxiety. Overall, I've been taking antidepressants for 15 years. What should I do about Lexapro? Reinstate? Quit completely? Feel like killing myself. Hugs, Melanie
  23. My boyfriend is now off seroquel and is having major physiological issues to the point that he is at his breaking point. I’m interested in seeing what others have done to improve this. I also am slowly coming off seroquel and am trying to get a better understanding.
  24. Hi, i'm new to this forum, so forgive me if i make mistakes, i'm still learning. I'm about two years out from withdrawing off of Paxil that i tapered down on, and about one year from one situational exposure to benzodiazepines, and two years from consistent benzodiazepine usage (the klonopin,) as i withdrew both the antidepressant and the benzodiazepine at the same time. I am drug free for an entire year. The drugs tagged in my post are also drugs i have been previously exposed to, or had other exposures in the same class of drugs, (E.g, i have also been exposed to zoloft, prozac, and pristiq in the "Serotonin Reuptake Inhibitor" category over the course of 14 years, though paxil was my last exposure to an SSRI drugs.) For the sake of simplicity, i will spare the details. I am posting here today because i am struggling with a couple issues that the specialists i've seen cannot help me with, and i hope to find resources here. I have ruled out thyroid issues, cardiovascular issues, vitamin deficiency in standard ranges, and other infectious disease issues through doctors and testing. I am debating about seeing an endocrinologist, but have lost a lot of faith in medicine since my psychiatric outpatient stent and the answers for my health that continue to elude me. I have listed my main issues below: 1. Fatigue - From what i've read and am trying to understand, fatigue can be a huge factor in antidepressant and benzodiazipine post acute withdrawal because of potential effects on hormones and neurotransmitters. I've also read that amphetamine withdrawal, especially in the context of abuse can cause fatigue, but my exposure to amphetamines was a decade ago, so i don't know if that could still be a contributing factor or not? The fatigue seems to come on intermittently, i drink green tea to help with wakefulness as the fatigue can feel debilitating throughout the day, and i feel like my brain just doesn't want to function on all gears. I am also sensitive to caffeine - if i ingest more than normal it can send me into a panic attack. My intermittent benzodiazepine exposure last year was in part induced by too much coffee, but i used to drink a pot of coffee a day without too much anxiety on paxil. 2. Emotional Blunting - I know that emotional blunting is also a factor in both benzodiazepine and antidepressant use and withdrawal, but i am a little perplexed that i still feel difficulty with emotional attachment. I theorize that this may be due to the benzodiazepine withdrawal mostly, for the reason that benzodiazepines inhibit or prevent neurological recovery from trauma, from what i understand. Is it possible that my body and mind are still in a state of survival even two years out from antidepressant and benzos? I understand that the psychological trauma from years of being medicated may also play a key factor in trust and developing relationships, but that is a psychological piece that should resolve itself through counseling, CBT, once the body begins to function correctly again. My other theory is that all my exposure to drugs over the years, (especially in the context of intermittent antipsychotic and benzodiazipine exposure) has caused irreversible atrophy to the neurological circuitry that is responsible for those functions (pre-frontal cortex and frontal lobe?) I'm looking for any input, resources, or suggestions that might help with those pieces Thanks, - NR EDIT: I don't have any recreational drug exposure either, all my drug exposure has been exclusively psychiatric with the exception of alcohol on a few celebratory occasions. I have also had antibiotic exposures on three separate occasions in the past five years.
  25. I have been diagnosed w ptsd, major chronic depression, bipolar2, and chronic pain. I take cymbalta 120mg daily, lamictal 100mg at night and bedtime. I have seroquel 25mg bid as needed. I am experiencing hypomania, irritability, discontent, and sometimes doc thinks its a serotonin syndrome in making. I know what that feels like. I took nucynta once for pain. Got off of it right away. So, i have permission by psychiatrist to play around w my dosage for comfort. I want to taper off cymbalta and lamictal, i have decreased lamictal by 25mg, at night. I have 60mg caps of cymbalta. I took 1 on monday, tues, and wed. Today i felt headachey, and my back pain flared up. I taught my swim lessons, came home and took the other 60mg. I feel better physically. I want to lower potential for hypomania,
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