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Hey everybody, for the third time within a year (and the second time since the middle of june this year) I experienced severe effects from a (low) dose of sertraline on my stomach and it feels like this time I done fucked up. Since three weeks after that last (12,5mg) dose of sertralin (stopped the taking immediately) I'm having a burning sensation as well as a hollow pain in my stomach (not the colon or small intestine), an inability to normally digest just eaten food resulting in burping up stomach content and the feeling of a balloon trapped below the last rib on the left. In addition to that, since the beginning of week 3, I have a nearly constant urge to burp (air), but the inability to do so for most of the time, which drives me crazy! The urge gets more present if I swallow a little sth, be it water or food, and (and thats curious) when I get up, meaning my chest is in a vertical position. I know these conditions since the last time I took a sertraline pill on an empty stomach only (yeah I'm dumb for taking it just with water), but it went away after 2 weeks. Now we are in week 4. Also I had learned sth from the previous mistake and took the pill after food recently - apparently it wasnt enough...or too soon after the meal; cause here we are. To clear things up: I stopped the medication right after the first incident in mid june (was on 50mg sertralin for like 6 weeks until this date) and only wanted to cushion some withdrawal symptoms with the latest low dose in early july and then this happened. In hindsight, I should have sticked with those symptoms instead of losing 6kg in 3 weeks as a 70kg male and all the mean stuff above. I know there are several reports about heartburn etc. but can someone actually explain what's in the sertraline that effects the stomach the moment it's in it (literally felt the balloon getting infalted at that moment) - shouldnt be the active ingredient itself (since it gets absorbed later in the gut) but some other ingredients!? Does it make a difference if I break the pill in pieces? And why the hell does it say "take with or without food" in the leaflet? Does any of you had similar experiences with sertraline (zoloft)? Did it make a difference for you to take it with food, or experienced some of you the same even if they had a meal before (would bring some inner peace to me). I think I have a severe chemical-toxical induced gastritis, probalby getting chronic atm. I'm on 40mg of esomeprazol since last week, no difference since. Would you up the dose? Swallowing the endoscope tomorrow, curious and anxious at the same time about the probable certainty 😕 Thanks much for reading through this and even more gratitude for replying! PS: please forgive eventual mistakes as i am no native speaker! Michael.