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ADMIN NOTE For tips for tapering your drug , find the link in this list Important topics in the Tapering forum and FAQ You cannot make a liquid from extended-release drugs, such as bupropion SR or XL, or drugs with a protective coating, such as Cymbalta (the type of Effexor XR that comes in a capsule filled with tiny beads is an exception). Many extended-release tablets are held together by a glue to retard their absorption. Mixed with water or other liquids, these tablets become a soggy glob. Otherwise, given variable solubility of drugs, what you're usually doing whe