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  1. Hi friends! I am a 24 year old male. I had been using Venlafaxine XR 225mg capsules for around a year and a half ( July 2017- April 2019). I'd started Venlafaxine for my chronic fatigue which was thought to be depression (it most probably was). Other drugs I used: -Pre Workouts(PW): Mix of Caffeine, PEAs, and a variety of nootropics. I used these almost daily to try to stay awake. They helped me enormously with school and social life; to the point that I got psychologically addicted. -Modafinil(rarely): Best antidepressant I've ever felt in my life when it was combined with the Venlafaxine. Not stimulating like the PWs, just made me feel completely normal. - 4 LSD trips over 1 year In March of this year I had decided that the Venlafaxine had not been having any major positive effects and that I was better off stopping it. Together with my psychiatrist we decided to taper off of it. At the time I didn't know about the importance of proper tapering and neither does my psyhiatrist. Her plan consisted of reducing to 150mg for 2 weeks and then 75mg for another two, after which I went down to 0. I had the classical 1-2 weeks of acute withdrawal with the brain zaps, nausea, depersonalisation, derealisation, extreme depression and anxiety etc. Followed by this I went through about 2 weeks of what I would consider complete normality and I thought I was out of the woods. Following those 2 weeks it got really bad. I got severe parestethias, numbness, extreme fatigue, anxiety, lack of concentration. Over a period of 1 month I failed 3 exams in med school. I was trying to keep myself focused and alert with the PWs and Modafinil but I seemed to be hyper-reactive to them. Sometimes they worked really well but sometimes they gave me this intense head pressure where I could theoretically see but it was more like a brain and "eye" fog. Before the withdrawal, and before every taking Venlafaxine, my tiredness, or low mood, or anxiety could be temporarily fixed by taking PW. I was not getting any of the functional use anymore. Since then, I've been getting waves of this sort of state, with waves of feeling "better", but I haven't felt close to how I used to feel on Venlafaxine since, or even before starting Venlafaxine. In other words I'm doing worse now than before starting the VF. In the worst parts of the wave I can't even take caffeine anymore without getting head pressure and a sense of overstimulation. Before all this it was like I didn't even have a threshold for how high I could go with stimulants without adverse effects, but now I take 1/4-1/8 of what I used to, and even that's risky. I'm not looking for the "rush" again, I'm just trying to be as transparent as possible with how my body reacts. For my last exam in July, I had a 3 week period where I took Wellbutrin IR 150mg so I wouldn't fail again. It seemed to help bring me a bit closer to stability, but again nothing like before. On Jul 5th I quit Wellbutrin cold turkey. As far as I can tell I've had no withdrawal symptoms at all. Nowadays I try maintaining stability by Meditating, taking Mg Glycinate( 400 - 800 mg ) and Fish Oil. I've also had another 2 LSD trips and one Mushroom trip. All of these have helped me with accepting my symptoms and powering through the day. I'm still taking low doses of PW to get any sort of semblance of energy and focus through the day. However, I'd ideally like to reinstate VF so I can taper properly and be stable. These symptoms are very disruptive and I'd love to go back to any semblance of my old stable self. Would it still make sense for me to try reinstating something like 37.5mg or 75mg Venlafaxine now and starting tapering? Is my only other option waiting it out? Sorry for the long block of text. Any advice is appreciated.
  2. Hi, I am 37 male (not a native english speaker so please excuse my english). I read a lot from this forum many other sources on the internet. I have been taking venlafaxine XR 150 mg several years, then switched to XR 75mg without big issues, after another year I tried taking only about half capsule. Couple of weeks later taking even less than half capsule daily I decied to go cold turkey. Bad idea! After horrible withdrawal, I gave up the fourth day and reinstated. I developed tinnitus since that, but I get used to it. Now I would like to taper slowely and get off this medicine. I have Velaxine from Egis (Hungarian pharma company) which come in small pellets (each about 0.30mg). Pellets have different sizes- they are obviously coated for extended release. Strangely they have also two colors- white and yellow (there are much more yellow than white pellets). Could it be that white pellets are with immediate release and yellow are with extended release? Also, I wonder if amount of venlafaxine is the same in each pellet and only the coat mass differs. Tried asking manufacturer and pharmacy, but they were reluctant to share any information:( I am glad to be here, always good to know we are no different and share our troubles.
  3. Hello to all! I was tapered, over a period of two months w/doctor's help, off of venlafaxine xr, buspirone, trazadone, and abilify. I had taken venlafaxine xr and abilify for 7 years and the other two for 14 years. Prior to the venlafaxine and abilify, I was on lexapro for 7 years. Considering the multiple meds and number of years of having taken them, I believe that my doctor tapered me down much too quickly. What is a real kicker is that when I contacted her to tell her I was having terrible symptoms, she diagnosed me over the phone with allergies and told me to go see my GP for further help. I did that, and he said they were all withdrawal symptoms. He assured me that time will heal me. He advised me to drink a lot of water, get exercise, and a lot of sleep. It's been over 5 months now, and I'm still symptomatic although they have reduced in minute degrees of intensity. I go from always being sick to feeling sicker and then back to being sick. My symptoms include burning, stinging, tingling skin on my arms; hot flashes (did those years ago with menopause); insomnia; lack of energy and motivation; icy-cold feeling hands, lower legs, and feet; brain-freeze feeling in the right backside of my head; and sensations of being stabbed throughout my body. The skin sensations are constant. The only thing I take now is fish oil--nothing else. When I first went off the drugs I also had terrible, intense, insatiable itching. The more I scratched, the more I itched. That has subsided, thank goodness. Has anyone experienced any similar symptoms? If so, did they eventually disappear? Did you ever experience a window? So far, I don't think I've had one. I would appreciate any help.
  4. Hello, I have recently learned that my body is experiencing a toxicity of sorts from taking venlafaxine ER. I started taking the brand name, Effexor ER, back in 2002 at about 37.5 mg for panic attacks. I tried to come off of it after a few years and experienced extreme panic attacks and was told by my doctor that I might have to take it forever like a diabetic does insulin. I resigned myself to this. Throughout the years as my depression and anxiety increased, the doctor increased my doses and eventually I ended up at 300 mg in 2017. The doctor assured me that although that was the max dose, they could go up a little bit more if I needed. I was actually hospitalized in March 2018 for pneumonia but the reason they wanted to keep me at the hospital was because my heart rate was 160. The ER doctor said it is common for tachycardia when someone has pneumonia and so I was kept for observation. After I recovered fully, I was sent to a cardiologist. After all the testing imaginable, they could find no reason for my heart rate to be so high. They also reported that I now also had high blood pressure when I never had it before. Life at this time was hard, I could not sleep because my heart was pounding and I felt constantly buzzed. I also started suffering from constantly cold feet, so much so that I had to use a heating pad at night and put toe warmers in my shoes during the day. The cardiologist tested everything and had me wear a monitor, but gave me no answers. He actually mailed me a letter that said he could not find what was wrong but that he included a list of disorders that might explain my symptoms. I suspected the medication and took myself down from 300mg to 150 mg. I experienced a mild depression but nothing really noticeable when I did this. I started to search for a doctor that would do more than send me lists. I eventually found one early this year who listened as I described symptoms (tachycardia, high blood pressure, sweating, tiredness, extremely cold feet, low body temp, headache, eye pain, ringing in ears, restlessness, restless legs, memory loss) and then asked my medications. When I told him the drug name, he said he thought it was a terrible drug and that nobody should be on it. He said he believed all of my symptoms were related to a toxicity from this drug and we needed to get me off ASAP. He described my cold feet as being vasoconstriction from the drug. He believed the sweating and fatigue is from my heart rate. He put me on a medication to lower my blood pressure and heart rate and is keeping me on the 150 mg dose until I return from a trip overseas. When back, he plans to taper me very slowly although I cannot remember the taper he mentioned. At this point I feel angry that I ever listened to the doctor who said I need to be on it forever. Fernweh Venlafaxine ER 300mg straight down to 150mg Metoprolol
  5. Hi I am currently on Venlafaxine XR ( 150 mg ) and have decided to reduce my dose as feel in a stable place to try. Me and my doctor decided to taper down using 37.5 mg XL tablets as this is the smallest dose they do. Anyway I had very bad withdrawl symptoms which began after about 1.5 days after dropping the dos by 37.5 mg After about 9 weeks and still suffering from withdrawls I went back up to my normal 150 mg XL dose which helped. My question is how do I withdraw any less that 37.5 mg as this is the smallest tablet and I believe you are not able to cut the XR version of venlafaxine XR. Thanks
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