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  1. I was put on 2.5mg of Olanzapine for racing thoughts/anxiety and as a sleep-aid. I was mostly taking 1.25mg though. I wish I had done the research before taking it!! I would have never taken it if I had known it would be like this, and cause such changes to the brain. So, I've decided to just stop taking it cold turkey, as I figure that having only been on 1.25mg - 2.5mg for most of the 3 weeks, and... (5.0 for 2 days near the end) it for 3 weeks total, it's best to just stop without adding length to the drug being in my system. The dose I've been taking is small also, however, I am very medicine sensitive. I'm so worried about side-effects from withdrawing... I was using the phone and laptop last night until 3am to distract me until I felt relaxed enough to try and get some sleep, which I eventually did at about 3.30am. I was researching all about Olanzapine withdrawals and looking at many videos people posted on YouTube regarding this. It was slightly comforting. I had very vivid dreams, as I have been having on the Olanzapine, only they somehow felt even MORE vivid. I can still remember the dreams easily enough if I try and this makes me feel anxious as I experience derealization/depersonalization every day I feel. I woke up a few times this morning. First at about 6am. Felt like absolute crap. Depression, comparable to the “come down” after a high from ecstasy etc. Managed to sleep again, even with an anxiety-induced racing heart, falling into that vivid dream-filled, seemingly shallow sleep. Woke again before my wife got up at 8am, but once again, managed to fall asleep before she left the house. It’s 12.15pm now, and I feel very depressed. I feel no joy and I have anxiety that is bubbling behind this cloud of depression. Obsessive, intrusive thoughts are frequent, and I don’t want to do anything at all today. I feel so very low. I find it extremely difficult to even write this, but I’m trying as I know it is something positive, to be keeping track of my progress. I really hope I feel better soon. I’m very nervous about what to expect. I feel like it can’t get worse than this, as I feel absolutely hopeless, with no happy feelings…I’m just so depressed. I’ve been thinking about trying Effexor XR, as I’m experiencing this crippling feeling of depression, and I’ve been feeling about the same way for the past 3 days, give or take. I actually started feeling this low after I re-commenced on Olanzapine 2.5mg after a 2 day trial of withdrawing from it after I took one 5mg tablet. I started feeling this low after taking that last 2.5mg tablet. Well, that’s all I have to write for now. I feel so low… (My question to people who have successfully stopped Olanzapine) - Will I ever feel ok again? Will I find the old me..? Is 3 weeks and the dose I've been on not small..? I was taking it for 3 weeks, and mostly (for about 75% of those 3 weeks) 1.25mg (splitting 2.5mg in half) along with taking 0.625mg (splitting the 2.5mg in half) as I’m very med sensitive and nervous in general about medication. UPDATE on DAY 2 of Olanzapine WIthdrawal It is now 5.10pm in the afternoon. I am still feeling depressed and have racing thoughts which are causing me anxiety on a high level. I feel like I have lost myself, and I'm afraid that I won't be happy again. This depression is so bad that I managed to talk to a psychiatrist in the day hospital and she prescribed Mirtazapine 7.5mg (taking half of 15mg). I really hope this will help me through this, as I am feeling rather hopeless and lost... Has anyone used antidepressants to ease coming off of Olanzapine? Thanks. UPDATE on DAY 3 I slept from some time after 1.30am while listening to a YouTube video. My sleep felt very shallow with vivid dreams, which I can't recall clearly now, but I don't think they were particularly good dreams. Woke up at 6am. Immediate panic. Still empty, no, worse... no feelings at all, just fear/panic. Perhaps this is due to my receptors being messed around with from the 3 weeks on Olanzapine? Is 3 weeks enough time to do irreversible, permanent damage to the brain? I wish I had some answer... I used my phone to watch videos of people's journey of withdrawing. I couldn't seem to find enough. I continued to watch videos until about 9.30am when I got out of bed with my wife. It is 10.20am now. I'm trying to remain active, even though doing things is just so difficult! I washed the dishes. I managed to eat a banana. My wife made me a cup of hot milk. Thinking about eating food makes me feel quite nauseated. I have zero appetite. My thoughts don't seem to stop. I wonder about the point of existence. Humans as creatures - what, really, is the point? I have depersonalization and derealization for at least 4 months now, and I think about every little thing I do or see... I'm just so tired and stressed! I'll continue to update. Thank you everyone, and I hope to hear some friendly people! Shane.
  2. Moderator note: link to benzo forum thread - Miko789: Xanax withdrawal/tapering Hi, I'm new to the forum, I have some questions I want to ask. My doctor prescribed effexor for depression, in 2009. Now I'm free of symptoms and I managed to come off with withdrawal symptoms though. That's with the antidepressant. Now I'm on Risperdal consta from November 2013 and seroxat 10mg. My doctor prescribed with risperdal consta 3,3mg/day long acting injection every two weeks. From February 2015 he lowered the dosage to 25mg/every 2 weeks equals 1,66mg/day. I tried to lower the seroxat 10mg but after 40-45h I have withdrawal symptoms vertigo, dizziness. Is it possible to cut down seroxat? How about the Risperdal consta (long acting injection). Has anyone tapered off completely without withdrawals? I read about the 10% harm reduction procedure to taper off and I'm going to tell my doctor and follow. thanks in advance
  3. Has anyone here taken zyprexa and healed after quitting the drug? What did you do to heal? How long did healing take?
  4. I was really stressed out after a breakup with a manipulative ex boyfriend and had a psychotic break in November 2016,I thought he was tracking me and was I was taken to hospital by my parents. While there, I read some material and then thought my ex was going to harm me. So they put me on Risperidone 1mg, saying it was going to help me get better. I think I took that for a week, complaining that it was too strong, they reduced the dose to 0.5mg for 2weeks. I hated the stuff and had leg twitching at night, so they took me off and gave me Ativan and Seroquel for 2 days. I then switched to Latuda 10mg for a week and one day, on the way to the hospital, I jumped out of the car, completely scared and was admitted again to the psych ward. (I think it was the meds b/c I felt confined in my seatbelt in the backseat and felt restless, plus I was feeling extremely suicidal). I was readmitted and given paliperidone (invega) which turned me into an emotional zombie and was taking 6mg for 2 months, I went up to 9mg for a week and they lowered it back to 6mg b/c it blunted me severely. I started to develop restlessness, so they switched me onto abilify (aripiprazole) 10mg for 1 1/2 months to try and get rid of the restlessness. It didn't work, but I did become more of myself on it. I was then switched onto 5mg olanzapine (zyprexa) and have been on it for about 1 1/2 months. It has made me gain weight, I haven't had a period in 5 months (I had a period when I was switching from abilify to olanzapine),I feel less motivation, less joy, thoughtless, constipated, etc. I am a 36yr old female and I used to be vibrant, funny, thin, centre of attention, outgoing, active and now I'm none of that. The doctors say I have schizophrenia and I have to be on these meds for 1-2 years b/c I had only one psychotic episode and you can try to come off the meds at that time (which scares me from hearing all the horror stories and I don't want to have the doctor put me back on these meds for the rest of my life). I had no mental illness before this and now all of a sudden I have this b/c I had a psychotic break and delusional thoughts for a brief period of time.
  5. Hi, I have been on olanzapine since December 2014 (2.5 years). I started at 10 mgs, then went to 5 mgs after 2 months. I then dropped to 2.5 mgs. Last August, I started 1.25 mgs day and stayed there until July 2017. I am now doing .625 mg/day since July 6. I am cutting this from a 5 mg pill. I am on no other medications. I stopped seeing my psychiatrist last Aug. I lost my insurance then. I have been doing really well and feel like I will be ok coming off. Even when I was seeing the doctor, I told him I could not stay on this forever as I've gained 30 lbs and I am afraid of diabetis, the dulled effect to my personality and other side-effects. I lapsed into a depression that lasted a few months when dropping under 2.5 mg. I felt with absolute certainty that it was caused from tapering down the medication and not a return of any illness. The depression lifted suddenly back in the spring and I've felt more like my old self than I have in years. The only side-effect I seem to have right now from the taper is difficulty sleeping some nights. It's not every night...probably 3 nights a week that I wake up several times in the night. I don't know where to put my question but I'd like to know if anyone has successfully come off olanzapine (Zyprexa) and when they did the final jump. I am taking such a small crumb of pill that I don't think I can cut it anymore. I am thinking that my next step will be to do .625 every other night. I feel happier today than I ever did while on olanzapine. It depressed the heck out of me and blunted my emotions greatly. I look at this tiny crumb I take every night and wonder if it is doing anything at all. Can anyone direct me where to go to post my questions? Thank you!
  6. Hello: I am new to this forum. I am tapering zyprexa. I was put on 10 mg in the hospital at the beginning of December. In the first week of January, I cut down to 8.50, then 7.5. for 10 days. Right now I am at 6.25 mg, and have been at that level for 1 week. They decided to put me on zoloft in the hospital as it "works fast" the doctors said, and is being used "until the zoloft kicks in". I am very impatient to get off zyprexa, and figured if I join your group, I would get support from people to help me be patient and wait enough time between cuts. Still figuring out how to do the signature. Will add it when I do. I am also on a whopping dose of 200 mg Zoloft, also given in the hospital. Before that, I had been 6 months free of Zoloft after tapering it for at least 3 years or even more. It was a huge disappointment to end up in the hospital and to have to go on it again.
  7. I’m having a very hard time with a withdrawal situation and I’m grateful this site is here. After dropping my Prozac dose to nothing, I came off 2.5 mg of Zyprexa last summer, very quickly. I tried to tough out the worsening withdrawal symptoms. I was getting manic until I became psychotic for three months.During the psychosis, I was often extremely restless, sometimes wanting to jump out of my skin. But I was also delusional and euphoric.When I got out of my second hospital stay, I was on Risperdal and Depakote. I’d come out of my delusional state, and was no longer restless, but I was still confused and just beginning to heal. Also, I didn’t have a psychiatrist, just refills. I’m sad to say that I was still eager to be off meds and thought I could titrate myself. I went off very quickly and, though the delusions didn’t come back, I soon became very agitated. I ended up messing with my meds on my own for three months. It was like I was trapped, unsure of what dose to take every night, wanting to stay on one dose but scared it was the wrong one. I was experiencing agony, including emotional fits and depression. I couldn’t sit still, and learned the word “akathisia.”I finally found a decent doctor who tried to keep me on a steady dose of Risperdal, as it could be worsening the akathisia, but I’d get back to a good place with it. When that didn’t happen, he switched me to 5 mg of Zyprexa, and, when that wasn’t enough, 10 mg (which I’ve been on a few months) That alleviates most of my suffering, but I still have trouble sitting still, reading, verbally communicating, and keeping my attention on one task. I also just don’t feel like the same person I was before this dreadful year, which is very frightening.Now my doctor isn’t sure if I have akathisia or agitation, or both. But my fear is how long it’ll last. I met someone who experienced this kind of condition for 10 years after coming off an anti-psychotic. I don’t want to be on 10 mg of Zyprexa that long, and I’m not even functional on that dose.Thank you for reading. I’m looking for some hope, or advice.
  8. I used to be very happy and funny guy who loved dancing and enjoyed going out with friends until one night I got drunk and someone put drugs in my drinks.I still dont know what that drug was but I felt like my legs were burning and I became very agressive and delusional.I got locked up for trying to brake into a house and send into a mental hospital. I was forced to take zyprexa for 3 months and after that zoloft for 2 months. Since then I lost all feelings and emotions. For all I mean: fear, love, hate, envy,everithing.I've Lost all my friends. No desire to live, I feel like an empty shell. Complete lack of creativity, lack of social skills Lack of empathy, lack of motivation and a sense of accomplishment. 5 months ago I stopped taking zyprexa but I have no improvement and Im beginning to think that my brain is permanently damaged by these drugs. Is there any hope that my brain will recover?
  9. Hi. I was at psyc ward after psychosis and my sleep was not perfect so i was put on zyprexa. I accepted to get out of there. I was on 20mg 2days then 10mg for 10days until i was released. When released I stopped cold turkey and and waited 3-4weeks before withdrawals came. Worst was my complete insomnia.. didnt sleep for 7 days so i had to reinstate. I went back on last dose 10mg. Immediately i felt it was a bad idea but i had to sleep. i tried to taper it off over a month. I had all side effects you could think so finally I just stopped again and used sleep pills to beat insomnia. Problem now 6months later(stopped oct2015) is that i still have insomnia. barely sleeps at all(1-4hrs) What advice do you guys have? From what ive read, this forum advice me to start on a small dose and taper from there am i right? I really dont want to reinstate since it slmost killed me but i dont know how to solve this either..
  10. Hi, I have a long history (18 years) of psych drug usage and have been on antipsychotics, antidepressants and mood stabilisers. I recently (1 month ago) started Zyprexa again because I had a crisis, and this time it didn't really work as well as it had in the past. I took 10mg and I passed out and felt awful and later was admitted to a private hospital, where various other drugs were added. I am now on 2.5mg Zyprexa and would like to get off it because I am pre-diabetic. Given that I have only been on it for a month, is a 25% reduction per week ok? I have withdrawn off it before and I am petrified. I feel in general that my mental health has declined quite a bit this year, so I am not sure if I could handle the withdrawal. Having said that though, going off it gives me hope that I will feel better and have my cognition back. Is this a realistic expectation? Zyprexa withdrawal is very rough. And unfortunately Zyprexa has affected my memory quite a bit. I am quite confused too at the moment, because I have seen too many shrinks and they all have different diagnosis and views for me. My shrink of 18 years pretty much gave up on me recently because I discharged against his advice from a private hospital where he consulted. I only did this because he wanted to start me on Abilify to replace the Zyprexa and after one dose, I had horrible side effects which he didn't believe. My life is in a complete mess at the moment and I am very sad at what psych drugs have done to me :__( Thanks Rico
  11. hello there. i registered here to search for help for symptoms that are bothering me and that came after 15mg of olanzapine for 7-8 months. generally, i've been taking olanzapine for like a year or something, i started with a 5mg dose at 2015, after some time they upped it to 10mg, and then i've had a full-blown psychotic episode and i began taking 15mg. i was hospitalized and there they gave me high doses of 5 different medications. when i came back home, things just weren't the same. okay, that didn't bother me, i was still thinking that it's only a phase. then, month after month, i realized that that "phase" is actually... something deeper, different. so i searched about it on the internet; and saw that "antipsychotics destroy brain". i stopped taking olanzapine cold turkey, which was DEFINITELY a very bad idea. at first, i was very depressed, i don't know if it lasted long enough to be called a major depressive episode, but it was severe. i was full of guilt... but, the worst of it all - i couldn't feel a damn thing. i couldn't enjoy a damn thing. i was on a winter holiday and i'm a skier, but i didn't feel anything while i was skiing. yes, i could leave a bed, but i was doing it only because i felt like the world around me would judge me and criticize me if i didn't. people are supposed to feel happy, free when they're skiing, even scared. i didn't feel anything. i realized that i stopped caring about everything, so, you could tell me a good thing - i would feel nothing (sometimes it was even hard to fake a smile, because it was even hard to move my face). you could tell me a bad thing - i would feel nothing. i had a fear of being criticized, but now, that faded too. but that's okay, to be honest, it's much easier to live without the guilt and at the same time energy to do anything about the guilt you're feeling. and i wanted to feel things. i wanted, and not only wanted, but i still want to feel things. deeply. so i started faking reactions to things... i was like - okay, imagine you're a normal person who didn't go through this kind of situation. how would a normal, rational person react ? and then i reacted that way. i still do that tho, it became some kind of a habit. my concentration is very bad. my will is very bad. i have anhedonia and apathy. my cognitive abilities are awful. but i just can't seem to care. and you know, sometimes you feel bad for not caring about things. i don't even feel bad about not caring, i just don't feel a damn thing. i had a period where i was doing better and was motivated to recover. i still want to recover, but i feel like nothing makes sense and i don't know how to get out of this nonsense. if any of you found sense, can you please tell me how ? i know it's an extremely hard and long process, but i somehow believe that it's possible. WHY ? i went to the neurologist and spent a lot of money on some neurological tests, for example magnetic resonance imaging of the brain. guess what ? IT'S NOT THE BRAIN. IT'S PSYCHE. mind. mental. !!!!!!!!!!!! at least for me. tests can't and don't lie. i believe in those tests, even tho i have all the symptoms of brain damage, i surely don't have a brain damage because i have an evidence. the tests have shown that my brain is perfectly healthy, despite my mental disorder. i don't know about you, but i can recommend checking yourself just to be sure, it can ease the pain, even if you do have a brain damage or if you don't. if you don't have enough money, there are local hospitals where you can check yourself. so that's why i accepted medications and i'm currently using 10mg of escitalopram and i started few days ago aripiprazole 5mg. i'm willing to try things. i just feel so brain-foggy and that's stopping me from doing anything. and now, i'll go and search the forum for some advices from you guys, i will write here again. thanks if you read this. ...and yeah, sorry for a really bad post, i'm not so well right now. i'm glad that i became the part of this community, the feeling that i'm not alone makes me feel better. and it's hell.
  12. jonathangalack

    jonathangalack: Zyprexa taker

    Hello there, how are you? I am a 33 years old french dude. I finished my withdrawal by tapering off since 2 or 3 months. I started taking this drug in 2012, because of insomnia due to a bad trip from a cactus named San Pedro. I started to withdraw myself from it in the beginning of 2016 and i finished the withdrawal 2 months. The more i advanced in the levels of tapering, the more i felt mental clarity and the more i had a good sleep (dreaming again). When i totally finished the withdrawal, i started having panic attacks, strange fatigue, anxiety, but, my sleep was even better. The more i lowered the dosages, the more i had mind clarity and the more my sleep was good. And, since i totally stopped the drug, even if it was hard at the beginning, it became more bearable. But, strange symptoms came back some weeks ago. It that normal? To feel better and then to have side effects coming back? I was exposed to stress, so, it could be the cause. Some months after starting the withdrawal (in 2016), i started to have pains in the body, inflammations, like fibromyalgia and it never disappear since. Because, i am really tired recently and when i think back, this strange fatigue started years ago and i now think i can associate it with a step level of my tapering off. I can totally recognize myself in the fibromyalgia symptoms (i have a lot of inflammations). I have weird symptoms since many years: -migraine -photo-sensitivity and eye tiredness -fatigue, tiredness -inflammations I took Zyprexa 16 years ago also, for 1-2 months, because of anxiety. And as the first migraine i had was after i took Zyprexa (not directly, but, after), i am wondering myself if Zyprexa would not be the cause of it and my photo-sensitivity i also had years after. I think i have fibromyalgia, etc, but, i tend to think more and more than Zyprexa could be the cause of my problems. I also have a lombalgia, one of my vertebra has recuced. I take supplements and try to go in the forest and do bare-footing, etc. I try to find all the activity and acts that could be good to the being and the body. I feel better sometimes, but my strange fatigue makes me stress sometimes and it accentuates the problem. Maybe the stress is the cause of the or a big part of the cause of this state of being. Well, see you, peace.
  13. Hi, ive been on Zyprexa 5 mg since November 27 2018 for a very stressful period in my life when I was suffering from high anxiety that caused chronic insomnia and some suicidal ideation i was on it for roughly 3 weeks after going through a difficult cross-country move, I managed to get myself off the drug, cutting from 5 to 2.5 to 0 within 2 weeks. from December 27th through January 4th of this year, I was drug free, feeling and sleeping great. then I got hit with another wave of external stress regarding a job opportunity in California (where I had just moved from) after 3 days of insomnia, my shrink advised me to go back on the drug. Dumb mistake. ive been on the drug since January 7th and have probably developed a physical dependence by now i want off this damn thing and I want my life back. 10 weeks shouldn’t make withdrawal has horrifying as I’ve seen it be for some people here Im mainly concerned with the insomnia. I have read threads where some people claimed success using gabbapentin and benzos to get through the sleeplessness, though I would probably just opt for the former. if anybody can share Zyprexa discontinuation success stories, please share. hoping to start cutting my dose this week.
  14. Hi, I've been on Zyprexa for about a month and a half now. I started off at 15MG for one month at a psychiatric facility after being diagnosed with Bipolar disorder. Since I've gotten out (about a month ago) I've been at 10MG for most of the last month and have recently cut down to 5MG. The side effects like tardive dyskenesia, diabetes (I am already prediabetic and genetically predisposed to it) along with potential brain shrinkage is not what I'm looking for, and I'm determined to get to the point where I can manage my own moods without medication. I have made an attempt to quit cold turkey, but unsurprisingly that failed miserably and about two weeks in I had to reinstate at 10MG to stop the overwhelming depression and eventual mania ridden with racing violent thoughts of suicide and harming others. Those two weeks were probably some of the worst weeks I've ever had. I was bedridden each day and entrenched in a deep depression rife with suicidal ideation. In an effort to avoid the horrid symptoms of withdrawal I have decided to lower my dose to 5mg, hold that for a month and then taper down to 2.5mg another month, then finally to no Zyprexa at all. Since 12-14-18 I am on Zyprexa 5mg, and things seem to be very manageable so far. The overwhelming depression I was experiencing is gone. I'm just very anxious/irritable and am vaping more frequently than usual. I intend to get off of nicotine once I get off of Zyprexa successfully. I take magnesium every night and use CBD oil twice a day. I have found that CBD oil helps immensely with anxiety, and the insomnia I had back when I quit CT. Running a mile each day or spending an hour on the exercise bike seems to help a lot with the anxiety. Am taking a 6 month leave from my senior year of high school to get off this drug. Since I just moved to a different city two hours north of where I used to live, I have no friends/support except a therapist I'm going to see in a couple days. I have already had facial/leg tremors, some weight gain, and am worried about developing TD. So glad to have found this online community - will keep updates on my mood and such going forward.
  15. Hi folks, First of all I'm new to this site, so feel free to tell me I'm in the wrong area or redirect me.. But here's my story... I currently have what I think is severe anhedonia. Last July, I was a bit depressed (I stress a bit, not majorly).......doctor gave me lexapro 10. After taking this, I vomited on the first night and developed sleep problems. Later in the week, I was given 25 seroquel which apparently would help balance out adverse effects of lexapro.......by the end of the week, I wasn't sleeping and I was suicidal. I subsequently was admitted to hospital. In hospital, I got more and more meds thrown at me and my mid august I was on 125 seroquel, 30 mirtazapine, 20 lexapro, 20 Olanzapine/Zyprexa....My main problem was the medication ripped my stomach apart.....the docs didn't believe me and just gave me more and more meds. I left hospital anyway on the concoction I mentioned.....I spent the following four months on these meds. During those four months, I felt no emotion whatsever, nothing. I felt suicidal, and that I would never recover. I had no desire to do anything. I just stayed in bed until late in the day, even though my sleep did not feel like real sleep. By mid November, i realised that the medication was messing me up, I demanded that I gradually come off everything. On that day, the doctor dropped the mirtazapine, and cut everything else in half. There was a quick taper, maybe too quick, and by christmas eve I was off everything. There were brief windows of emotion during the taper but still 95% anhedonia. Days after I went off everything....I cried for the first time in six months.....days later I laughed for the first time in months... I'm now 6 weeks off everything, I had huge headaches up unitl last week. My stomach started to improve after going off everything and is on the mend. However, I'm still worried about emotions/desires/thoughts etc.....over the last six weeks....I've had maybe 5 occassions where I felt strong positive emotions...and maybe 3 times where I've been sad/angry to the point of proper crying. outside of those 8 occassions, there's still an awful amount of flat feeling, apathy etc... I'm worried and wonder how long or if I will recover at all. Feedback welcome!!
  16. Hi guys, I’ve been doing some research into histamine since I believe it plays a very key role in the withdrawal process--at least from the medications that I’m on. I will summarise what I’ve found below as well as the potential impact it could have on managing the withdrawal from antipsychotics such as Zyprexa/Seroquel. I searched this forum but couldn’t find any good overview or discussion, so hoping this can help people. Many of the popular antipsychotics such as Olanzapine/Zyprexa and Seroquel/Quetiapine have a very powerful antihistamine effect: only a very small amount of these medications are required to block the H1 Histamine receptor. Zyprexa, for example, has a Ki(nM) of 0.65–4.9 according to Wikipedia, which is incredibly low (the lower the Ki(nM), the smaller the amount of a medication is needed to block a certain receptor). Therefore, withdrawing from histamine-blocking medications (Zyprexa/Seroquel) is associated with increased histamine (as the blocking effect is reduced, histamine levels become elevated). Certain groups of people might have even had a histamine intolerance and/or high histamine before going on psych-drugs (and both histamine intolerance and high histamine--also related to under-methylation--have been linked to psychosis and other psychiatric disorders), so coming off histamine-blocking medications can also exacerbate this pre-existing imbalance, on top of the effect described in the point above. Histamine is a neuromodulator of the adrenals, so elevated histamine can make the adrenals release a lot more adrenaline, instigate ‘fight or flight’ mode in the body and cause severe anxiety. There is also a strong link between histamine and sleep; having high histamine can cause insomnia. Interestingly, histamine levels naturally peak around 3am/4am, which is when many people experience cortisol spikes and unwanted adrenal activity. Sound familiar? All of these symptoms are very common in the withdrawal process, as we unfortunately know. When withdrawing from histamine-blocking medications, you can take steps to bring down histamine levels to help manage the adverse effects mentioned above. I’ve found anecdotal success stories online from the world of integrative medicine; Alice Lee (MD) says: “If you ever want to successfully reduce a medication that blocks histamine receptors, you will need to know how to lower histamine levels.” Lowering histamine levels can be done through a combination of diet and supplementation: 1) Follow a low-histamine diet (google it for more info!) 2) Through supplementation - taking a histamine digester that ‘chews up the histamine in food’ - Alice Lee recommends Histazyme (by Dr. Amy Myers, MD), but I’ve also seen Daosin 50 and other brands which all contain the same ingredient, Daimine Oxidase 3) Supplementation - natural histamine blockers like Allqlear by Integrative Therapeutics, Histaplex A-B by Biotics Research, or Opsin II by DesBio. Avoid xenobiotics for antihistamine support, such as Benadryl, because the body will react with an inflammatory response to a xenobiotic. I know that this kind of integrative approach is generally a dirty word on this forum, but for me it makes too much sense to ignore. Most of this advice comes from Alice Lee, who is a “holistic psychiatrist” who actually went through the withdrawal process herself, and reports impressive success stories weaning her clients off all kinds of medication (APs, ADs), just check the testimonials on her website TL;DR: I’m going to try a low histamine diet (being more careful around the time when I make a cut to my medication), as well as adding some of the anti-histamine supplements and histamine digesters. I will still be tapering using the 10% method. If anyone else has research or real experience in this area, I would be very curious to hear it. I think it is a very under-recognised factor and understanding more could potentially make for a smoother withdrawal. I'm also conscious that it's only one piece in the puzzle, and there are other receptors to tackle too. But for insomniac, Zyprexa-dependent folks like myself, it could be really key. More reading and links to the success stories can be found here: http://www.holisticpsychiatrist.com/viewpoint/2018/6/7/understanding-histamines-connection-to-mental-health and http://www.holisticpsychiatrist.com/medication-withdrawal/ https://beyondmeds.com/2014/07/13/histamine-psych-drugs/ and https://beyondmeds.com/2013/01/07/histamine-intolerance/ from around 33 mins https://www.mthfrsupport.com.au/dao-deficiency-and-histamine-the-unlikely-connection/
  17. rajp

    rajp

    post moved from andy: Finally off zyprexa Hi, I went to see the doctor and he took 5mg of my dose in one go. I was on 10mg day. 5mg at night, 2.5in the morning and 2.5 in the afternoon. He said I dont need the morning and afternoon dose. I was ok the first week but this second week I think im feeling withdrawal symptoms As I've dropped 5mg in one go , any ideas how long the withdrawal symptoms will last ? Should I go back to my doctor and ask to be tapered off slowly ?
  18. hi, Alto I went to a local pharmacy and they helped me to compound 2.5mg pill into 2.mg. but they changed it into a capsul form. would that make a difference. now my son is taking 2.5 pill and 2capsule. what you think. the pharmacist said it is fine.
  19. Alright, the reason I started this topic is a need a good advice. My problems started September last year, after turbulent relationship and quite possibly due to overtraining I suffered a mental fallout, father panicked called my brother who in turn called the police to take me to the mental hospital, which I refused to go on my own volition. The cherry on top is my mother was a paranoid and committed suicide two decades ago by refusing to take her prescribed meds, so I knew if go through the system I would end up a Poll-drugged zombie. here was my therapy: Valproate 500mg, Haldol 8mg Prozac 20 mgOlanzapine 5 mg Biperiden 2 mg Ativan 5 mg I managed to wean my self to lorazepam 2.5 mg Haldol 0.5 mg Olanzapine 1.25mg three months ago I jumped from Haldol 0.5 mg and a week after from Zyprexa 1.25 mg thinking that antipsychotics are easy to get off (i was stable at the time on these doses) for first two months i suffered anxiety, depression and suicidal thinking, but I managed to shrug them off as withdrawal symptoms, the problem is after approximately 9 weeks I started to suffer 24/7 insomnia, I could fall asleep but would wake up in 30 minutes, that lasted for a couple a days, not wanting to end up hospitalized again i reinstated 1 mg Haldol and 3.75 Zyprexa, at higher doses of both these drugs I get extremely restless, on lower doses I can barely sleep, right now i sleep between 6-8 hours but during the day I am extremely agitated for having to drink these poisons, i went to a couple of reputable shrinks who wanted to up my doses, particularly Zyprexa to 10mg, which I refused. My question is should i listen to these shrinks, or try to though it up and remain at these dosages and try to stabilize? Thanks in advance
  20. Hello fellow withdrawers (if that's a word), I'm Bokart and I'm here on a journey to quit my medication of Olanzapine. Down to 7,5 mg at the moment (see my signature). My story short: back in February 2015 I got admitted in psych ward due to psychosis (due to my destroyed sleep because of my night-shift work). There began my involuntary medication of Olanzapine, which pulled me out of a psychosis, so at least it did some good. I was released from the hospital after two weeks of being there. Now, after jojoing with my olanzapine dose (see signature), I'm finally set to quit it for good. I found this community after searching for succesfull withdrawal stories on the internet and found this community to be great, people being helpful and supportive and giving good advice... I know it can get rough when I approach smaller doses so I do know I will need support. And hopefully I can give support too and offer people hope after and during my taper. I know lots of people are in the same boat as me. Why I want to quit? I got no sexuality anymore, my motivation lacks big time, even personal hygiene is suffering because of that. I can't memorize things like before - learning is difficult. I have very little emotions left in me, basically I'm a dumbed down version of myself nowadays with this drug. I have little social skills - which I would badly need because I plan on working with children in school so some situational awareness is needed (I might have to quit my studies due to me making no progress in my studies... due to this drug). No happines, no enjoying things, lethargy and demotivation... About my psychosis, after it was gone I haven't had any symptoms of it returning (like delusions, paranoia, hallucinations), even after trying to quit my drug cold turkey once, which I see as a good sign. Now I don't want to slip into psychosis again so I need to be extra careful with my taper. After I hit 5,625 mg I will go on tapering by feeling, so no reductions until I feel stable enough. My main concern is sleep. I have a prescribed medication of temazepam (a benzodiazepine), which I can use when my insomnia has hit a threshold of needing immediate attention. I'm trying to limit my use of it to every three days to prevent tolerance and dependence (I know benzodiazepine withdrawals can be bad). But the thing is, lack of sleep led me to psychosis once, so it is a big deal to me. I need at least one night on a while to hit at least 4 hours of uniterrupted sleep, which 40 mg of temazepam does. I've tried many other sleep aids such as low to medium dose of quietiapine (no effect), low to medium dose of levomepromazine (didn't help), low dose of doxepine (no effect), even melatonine and l-tryptophan and 5-htp and none of those helped. One thing that helped me though was phenibut combined with temazepam - I slept 13 hours with that combination! So I know I have an emergency brakes on my train now (assuming that combination works again, haven't taken phenibut in 2 months to avoid tolerance and dependency), but I'm planning on limiting the use of this combination to once a month. On this dose of 7,5mg I'm currently having 2-3 hours of good uninterrupted sleep plus 3-4 hours of bad, constantly waking up kind of sleep So, thank you all for being here! And I wish a speedy recovery to those who are withdrawing from their drugs, we are all here together.
  21. To anyone with experience,... I’m currently on a taper from olanzapine and 1.25 mg is my current dose, in 30 days from now I want to make a cut. My original plan was to just to cut the 1.25 mg piece in half to 0.625 mg making it a 50% reduction which I know is not the 10% taper as suggested, the main reason for this particular cut is because it’s just easier to cut the pill. The last time I made a cut was from 2.5 mg to 1.25 mg and before that from 5 mg to 2.5 mg, when I did that I had mild withdrawal symptoms a little bit of anxiety, lightheadedness and luckily no sleep disturbances, 2 weeks after I tapered and stabilized, I felt almost like I had been feeling when I was taking 5 mg (feeling normal with the 2.5 mg dosage then feeling normal with the 1.25 mg dosage). Keep in mind i worked my way down to 1.25 mg from 15 mg daily so a good amount of progress. My question is, how would I make a 10% reduction from my current dose of 1.25 mg with such a small pill and have it be an accurate cut, cutting the 1.25 mg piece in half just seems easier as I mentioned but I know it doesn’t mean safer, I know going slow is recommended first over jeopardizing my well being. As I get closer to getting off this medicine I get more nervous, I just want everything to go smoothly. I know everybody’s body and mind are different some people can handle significant drops while others cannot, I’m just wondering since I had success with bigger cuts in the past and my symptoms where manageable am I able to repeat the same pattern. If anyone could chime in and let me know what you think or how I should go about the rest of my taper it would be highly appreciated. Me personally, since I’ve made tremendous progress thus far in tapering I’d rather go slow like 10% every 4-6 weeks so I can have a successful safe taper but on the other hand if withdrawal symptoms are manageable then maybe more significant of a drop, I don’t know. Please tell me how to taper 10% from 1.25 mg as well as any recommendations that anyone may have, any input is welcome. Thank you, -Brock P.S. I’ve been on zyprexa since June 2018 so a total of 9 months.
  22. Hello I always wanted to return to the site and thank all that helped me in the dark hours and also the forum owner and originator for the tireless work that has helped so many people Heres my thread when I first asked for help http://survivingantidepressants.org/index.php?/topic/6865-andy-hello-tapering-from-zyprexa/ I wont go into how I finally quit the drug because it wasnt the normal 10% approach although I tried 5 times and failed miserably.I found a good understanding doctor who helped me reduce and more than anything listened to me without prejudice.This helped enormously,I finally jumped off at 1.25mg and to be honest it wasnt to bad,by far the worst reduction was going just under 2.5mg,I had severe migraines ,nausea,heart palpitations,sickness,depression,mania,mood swings and relentless insomnia.The insomnia was by far the worst symptom as it made me anxious and very irritable ,all this while trying to be a good father and holding down a very stressful and demanding job.Of all the drugs I was put on Zyprexa was the hardest to quit,it was hell and back but it can be done I have recently started my Taekwondo training again that I practiced for over 15 years but couldnt while I was on this terrible drug,I now feel calmer and sleep well.I put on over 3 stone while on zyprexa even though I ate a well balanced diet,I felt lethargic and had no interest in life,that has all changed and the weight is coming off steadily. Excercise has been the most helpful tonic for me and even when I had had zero sleep I went to my class and worked out.It slowly but steadily improved my sleep and made me feel confident again that I could get over all of this,when you start to see improvements you start to see light at the end of the tunnel Things are heading in the right direction and my outlook on life is positive once again.I feel good Once again thankyou for all your help and for people just starting the journey dont ever give in it can be done,god bless you all Andy
  23. Evoldnahturt

    Evoldnahturt

    The relevant facts of my life: - I've had trouble sleeping all of my life, I'm usually sleep deprived. - I'm anxious off and on, usually on. Often times the anxiety gets bad. I've been like this for at least 15 years. Probably, at least to some extent, most of my life - I believe I may have been depressed most of my childhood. It got bad in my late teens and has improved, but remained. - My diet has been terrible all my life. No fruits or veggies. Just processed junk. - I was put on Ritalin when I was a kid and took it for many years. It caused me to develop ticks that have gotten better, but pop up sometimes, especially when I'm stressed. - I became suicidal in my late teens and was put on a lot of different medications. None of them worked and I didn't stay on them long. - I took between 2.5mg to 5mg (because I was too lazy to cut the pill in half at times) of Zyprexa for about 14 years starting when I was around 19. - I took Prozac for many years starting at around age 19 and quit CT with no problems several years ago. - I used alcohol off and on over the years. I quit for a long while before it quit getting me high. I noticed that it started working again after I quit Prozac. I started drinking again heavily for a few months, and then once or twice a week off and on after that. - On rare occasion I would pick up a small batch of pain pills. I usually used 5mg-10mg of Hydrocodone, but a couple of times I went overboard. - I used other miscellaneous pills on rare occasion in my late teens. - I smoked marijuana daily for many years and slowed down to a few times a month over the past few years, near the end it was usually just when I was out in nature. I recently quit smoking completely. I don't believe it was causing problems, but I've decided it's not worth the risk. - I was bulimic for over a decade and quit over a year ago. Summary of my withdrawal: 1.25mg weighs 47.5mgpw (mgpw = milligrams pill weight) when weighed on a scale (I use a GEMINI-20). I dropped to 47.5mgpw (1.25mg, quarter of a pill) for somewhere between a few months up to a year. I started quickly tapering sometime around or soon after September 2015. At first I was able to cut my dosage quickly, but things got rough at times and I ending up having to jump back up almost to where I was before I started reducing my dosage. I kept lowering my dosage, often getting to zero, and then raising it again when things got too difficult. I did this for about five months. My first symptoms were pressure in my head, a loss of feeling throughout my body, and fear. Sometimes, I believe, the fear was caused by the other side-effects. However, sometimes I experienced the sensation of fear out of nowhere without being afraid of anything. I usually would then become afraid of the sensation of fear getting worse. In retrospect, I believe these and other effects were triggered or worsened by my taking (at different times) Xanax, Omeprazol, Hydrocodone, and alcohol during Zyprexa withdrawal. It quickly became clear that alcohol was causing me to become fearful, because the effect was immediate. I haven't used alcohol directly since near the beginning of this process. I did, however, use it in the form of Zzzquill, which caused hypnic jerks with the sensation of fear while drifting off to sleep all night. I ended up realizing that Xanax was also causing problem, after using it throughout most of my withdrawal. I later tested using Hydrocodone to see if I could at least handle pain meds. It caused me to feel the sensation of fear while falling asleep that night. Things got really difficult the days leading up to 2-14-16. One of my step-brothers drove me to my mother's where I stayed for a week and a half. I ended up increasing my dose to 142mgpw (3.75mg, 3/4 of a pill). While I was at my mom's, I saw her doctor to get some lab-work done as well as a neurologist. The neurologist did an MRI scan of my brain. A benign lesion was found, but nothing else. The lab-work all looked fine except for the fact that my good cholesterol was low. My mother has been very supportive, but my family has had a hard time believing that these issues were caused by the medication, which baffles me, but I'm very grateful that they're supportive. I've been surprised by how unsupportive many families can be. I have reduced my dosage by 10% a month (calculated from the previous month's dosage) since then. I held for two months initially. My symptoms quickly got better at first and have slowly continued to improve. I can't tell if they're still improving or not. I'm holding at my current dosage for at least another month next month, probably longer. I was initially eager to get my dosage down, I now realize that I should probably slow down to be safe. I'm currently at 104mgpw. I've decided to avoid all other medications for as long as possible. I'm not sure what I'm going to do if something happens where I need medication. I'm also not sure how long I want this taper to last. Stories like Mapleleafgirl's (4 year taper, got very sick 20 months after the taper) make me want to take longer than my body tells me to, like six or eight years. I'm very grateful that I'm doing as well as I am and that reinstating Zyprexa has made things much better, but I got past my breaking point in just a few months with much less severe issues than what many of you are dealing with. I don't understand how you can take it. I have a stronger will to live after going through this, but not strong enough to suffer like that for years. I would have to kill myself and I can't stand the thought of doing that to my mom while she's still alive. The stories on here, what's happened to me, and the fact that I'm still not fully healed after four months of taking a larger dose really scares me. I'm a lot better and what's persisted is manageable, but I figured I would have healed by now. I promise that however this turns out, I'll provide you guys with updates over the years. Symptoms I've experienced: - Pressure in head - Burning sensation throughout my body, especially in my thighs and legs - Arm, leg, upper body, finger, or hand jolts (especially when falling asleep) (Hypnic jerk?), I've had this, to some extent, for many years, but it got worse during withdrawal - Tingling, numbness - Pins and needles (especially when falling asleep) - Knots and frequent noise in stomach - Extreme difficulty swallowing food (briefly before I increased to 142mgpw) - Irregular heart beats - A very hard heart pump that makes me tense up (not as frequent now) - Ringing in an ear (not very often these days) - Pressure in an ear - Tachycardia, especially when getting sleepy, falling asleep, and twice while asleep (woke me up) - Blurred vision when waking up as well as dizziness (this persisted throughout the process of weaning off of Zyprexa, it stopped when I increased to 142.5mgpw (3.75mg)) - Burred vision and dizziness outside of waking up in the morning, this wasn't very frequent - Muscles twitching, like after a workout, but more frequent - Akathisia - Insomnia, I've always been an insomniac, but it got much worse in the beginning and then got back to normal early-in - My mind has been slipping. I'll say things that don't make sense. I'll say I'm hot when I'm cold. I take a long time to come up with a response. This has been the case for years - Other things that I couldn't describe. I've found that if I can't describe something, I forget about what it was like eventually.
  24. Hi, I discovered this site through http://cepuk.org/support/ I was forcibly drugged with Zyprexa/Olanzapine off and on between 2003 and 2005. I tapered off slowly through 2006. I am now drug free. However I am still healing serious brain damage. There have been improvements but I still can't work. I've got to the point now after reading Deadly Medicines and Organised Crime - https://www.amazon.co.uk/Deadly-Medicines-Organised-Crime-Healthcare/dp/1846198844 - where I have the evidence and confidence to seek financial compensation through a clinical negligence solicitor. I already have names of 249 clinical negligence solicitors that accept legal aid. I found this through the Law Society - https://www.lawsociety.org.uk/ - but I need to find the one's who have experience with psychiatric drug claims. So if anyone has experience with good, well run solicitors who can really fight my corner then I'd be very interested to know about it. I had known for many years of serious problems in pharma industry but I was shocked to the core by Peter Gotzsche's book. Probably the most important thing for me has been other examples of corruption. Transparency International is a very good organisation - https://www.transparency.org So at the moment I need to concentrate on getting financial compensation if I can. I do not have a proper place to live and need to buy my own property so I can move along with healing and helping other people. God bless.
  25. Hi, I am currently on 15 mg of remeron. I tried to stop when tapered sucessfully down to 3.75. I had withdrawals with anxiety that made me sucidal and I had to go to the hospital. I have come off all other drugs sucessfully in the past. I am scared to death about ever coming off and wondering if I ever should come off. I keep wondering what happens in the future if some reason I can't get the drug. I constantantly obsess now about getting off the drug to the point I've had to go back on tranxene to keep the anxiety down from worring about coming of this drug some day. Should I just stay on it. If it permantly damages the receptors and they don't repair in your brain would it be best to just stay on it. I have GAD so I may need to stay on a drug for life. I got off prozac some years ago and lived symptom free for 4 years until a bad life trauma caused me to have debilitating anxiety for months. I could not work and could not eat. I dropped down to 100 lbs and had to be hospitalized. I have been stabilized on remeron now for over 2 years. Should I try to stop or would it be best for me just to stay on? If I stay on I'm just going to worry about it until I crack up. Right now I found a doctor in Ashville NC, Dr. Daniel Johnson who specializes in helping people safely withdraw from these meds. He has not returned my calls at all. Maybe he is on vacation or something. I even tried contacting Dr. Peter Breggin.. I'm so scared that if I try to come off my brain will be damaged permantely and will not recover. I know I should think like this but even the slightest anixiety can make me suicidal. I don't know if I can ever risk a withdrawal. I had to go to the hospital for my first attempt at this withdrawal. Some of it could have been extra anxiety by worring about the withdrawal rather than the withdrawel itself, but I don't know. Help, I'm scared to even try. Cheryl
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