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uncomfortablynumb: withdrawal symptoms or anxiety / depression


uncomfortablynumb

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Hi, I found your thread because I related to some of your symptoms. I know you have been asking if anyone recovers from this... I wonder the same thing... but it sounds like you are someone who has recovered from this in the past... so I think you can again. Sorry to hear you are feeling this way though, it is awful.

- 2003 to 2015: celexa, 20 mg, ~12 years

- 2015: easy switch off celexa and onto cymbalta, 30mg

     (over a decade of fantastic years in here, with one anxiety/depressive episode brought on by a breakup, which I got through with therapy, tools, etc)

- 2017: Nov/December: tapered off cymbalta, 20mg --> 0, over 1.5 mo. in conjunction with my (former) psychiatrist. Zero date: 12/15/17

     (I was just sort of curious to try being off meds after so many (great) years. I wondered the degree to which meds may have been affecting my sex drive/orgasm/access to deeper emotions. After going off was ok for about 3 mo... then: horrible anxiety, panic attacks (first time in 14 years and way stronger than I ever had before), agitation, suicidal depression, crushing physical sensation, anhedonia, dp/dr, emotional numbness. Horrible.)

- 2018, July 21: Tried going back on celexa, 5mg

    (HORRIBLE adverse reaction, discontinued after 10 days, stopped 7/31/18, thought I would need to be hospitalized)

- 2018, Aug 3: Tried remeron, got up to 15mg for 14 days, then tapered back down to 3.5 mg/d (super sedating, couldn't think and could feel even less)

- 2018, Sept 7 - Oct: Restarted Cymbalta, ~4mg (sept 9, stopped the 3.5 mg of remeron). Went up to 13 mg Cymbalta, then right back down to 4.5mg.

    (Now see it as withdrawal and am wanting to get off and heal.)

 

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  • uncomfortablynumb

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MMMM - how long have you been going through this?   Last time I got off Remeron then Ativan I suffered with these symptoms but it didn't last nearly as long.  I feel more numb and blank this time around or maybe I forget what it was like.  I am scared though.  Life has become a non-experience.  Can't feel anything.  I am almost 40 now.  Still pretry young so if this is permanent it is could be a long wait to die.  

 

Do people usually not recover from the depersonalization and numbness?  It has been 9 months now of dissociation and being emotionless.  Have not felt any happiness or laughed this whole time.   

 

Not sure if this was caused by kindling (alcohol) or trauma/life stress (death in family, moving etc.). Does it matter in regards to recovery?  Feel empty and brain damaged.

2006-15 Effexor on and off mostly on. Also tried drugs that didn't work; notriptyline, Celexa, Zoloft, Welbutrin, Abilify, Pristiq, Cymbalta. Weaned off Effexor for last time quickly (2015) - horrible depression, anxiety, and insomnia.
Remeron (2016) helped wd symptoms. 
2017 - tapered off Rem over a few mths. Horrible wd symptoms with insomnia. Reinstating Remeron fail. For wd insomnia tried: Trazodone, Elavil, Gabapentin, Seroquel, Doxepin, Valium. Failed. 2mg Ativan at bed intermittent use 4mth.
CT Ativan - off all meds June '17.  Recovered by Oct '17 - well for a yr.
Oct '18-now. Major stresses, drank alcohol. In hell -insomnia, dp/dr, head pressure, anhedonia, no emotions, blank mind.
May/June '19 - 16 doses Rem CT, 10 doses 2mg Ativan. CT

Recovered Oct 2020-June 2022 - fully functional, working.  Only left with head pressure.

Major stresses - mainly financial, living space, relationship - severe insomnia, severe anxiety, depression, dp/dr, emotional numbness, blank mind

Sept 2022 - for sleep - took 8 doses of 15mg Remeron, 3 doses of 7.5mg, 3 doses of 3.75mg, 3 doses of 1.875mg

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  • 3 months later...

I am still suffering from severe insomnia (never get over 2hrs sleep), head pressure and brain burning, emotional blunting, blank mind, dp/dr, anxiety, depression, and tinnitus.  Is there anything I can do at this point?  Is this stuff even going to get better?  Very difficult to continue on like this.  

2006-15 Effexor on and off mostly on. Also tried drugs that didn't work; notriptyline, Celexa, Zoloft, Welbutrin, Abilify, Pristiq, Cymbalta. Weaned off Effexor for last time quickly (2015) - horrible depression, anxiety, and insomnia.
Remeron (2016) helped wd symptoms. 
2017 - tapered off Rem over a few mths. Horrible wd symptoms with insomnia. Reinstating Remeron fail. For wd insomnia tried: Trazodone, Elavil, Gabapentin, Seroquel, Doxepin, Valium. Failed. 2mg Ativan at bed intermittent use 4mth.
CT Ativan - off all meds June '17.  Recovered by Oct '17 - well for a yr.
Oct '18-now. Major stresses, drank alcohol. In hell -insomnia, dp/dr, head pressure, anhedonia, no emotions, blank mind.
May/June '19 - 16 doses Rem CT, 10 doses 2mg Ativan. CT

Recovered Oct 2020-June 2022 - fully functional, working.  Only left with head pressure.

Major stresses - mainly financial, living space, relationship - severe insomnia, severe anxiety, depression, dp/dr, emotional numbness, blank mind

Sept 2022 - for sleep - took 8 doses of 15mg Remeron, 3 doses of 7.5mg, 3 doses of 3.75mg, 3 doses of 1.875mg

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  • Administrator

As you know, we're not in a position to recommend drugs for sleep. Have you tried any of songbird's suggestions, or any of these?

 

We have to think in terms of very gradual improvement. Anything you can do to improve your sleep a little bit is good.

 

Are you getting at least a half-hour of gentle exercise, such as walking, every day?

 

Are you avoiding alcohol and caffeine?

 

On 4/25/2019 at 10:59 PM, Altostrata said:

 

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

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Hi Alto, 

I have cut out caffeine and alcohol.  I only have had decaf a few times in past few months.  Back before Hell broke lose late last year I remember my last time drinking.  The alcohol had no effect on me, like no regular inebriated feelings.  Strange.  Also at the same coffee didn't give me the regular perk up.  It is really messed.  Wonder if those are signs of a screwed up nervous system.  

 

I have been trying to go for regular walks and get sun.  I have taken melatonin over the last few months at low doses up to 5mg.  Not sure if it has helped because never have gotten over two hours. Think it might be making me more depressed and head pain worse.  

 

Have tried progressive muscle relaxation in bed and didn't help.  Also any audio seems to keep me awake.   

 

I could try and stay away from blue light a little earlier since I have failed at that.  I tried using my blue blocking glasses but that hasn't helped.   

 

Is the head pressure and burning some sort of nerve damage like central pain syndrome?  This symptom is pretty disturbing.  The loss of self and personality is hard to live with too.  Feel erased.  Do you know of others who have recovered from these things?  

 

I recovered from this situation before.  But this time it is not improving and I am afraid of it being permanent.  

 

This is all a nightmare and I probably need some dental work done including removal and replacement of mercury filling and a filling or root canal.  Been holding off but I am just not getting better.  

 

2006-15 Effexor on and off mostly on. Also tried drugs that didn't work; notriptyline, Celexa, Zoloft, Welbutrin, Abilify, Pristiq, Cymbalta. Weaned off Effexor for last time quickly (2015) - horrible depression, anxiety, and insomnia.
Remeron (2016) helped wd symptoms. 
2017 - tapered off Rem over a few mths. Horrible wd symptoms with insomnia. Reinstating Remeron fail. For wd insomnia tried: Trazodone, Elavil, Gabapentin, Seroquel, Doxepin, Valium. Failed. 2mg Ativan at bed intermittent use 4mth.
CT Ativan - off all meds June '17.  Recovered by Oct '17 - well for a yr.
Oct '18-now. Major stresses, drank alcohol. In hell -insomnia, dp/dr, head pressure, anhedonia, no emotions, blank mind.
May/June '19 - 16 doses Rem CT, 10 doses 2mg Ativan. CT

Recovered Oct 2020-June 2022 - fully functional, working.  Only left with head pressure.

Major stresses - mainly financial, living space, relationship - severe insomnia, severe anxiety, depression, dp/dr, emotional numbness, blank mind

Sept 2022 - for sleep - took 8 doses of 15mg Remeron, 3 doses of 7.5mg, 3 doses of 3.75mg, 3 doses of 1.875mg

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  • Administrator

Those are symptoms of a nervous system destabilized by adverse drug effects and withdrawal.

 

Please do what you can to improve your sleep environment, if only a little. Melatonin is best taken at nightfall -- around 9 or 10 p.m. at this time of year. Even 0.25mg can be effective. You'll need to take it at the same time each night and turn off the lights for it to do its work. This may not happen immediately.

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

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  • 4 months later...

Hi @uncomfortablynumb so sorry to see you suffering so much. I can relate to almost all of your symptoms. Just wanted to see how you are doing? :)

Clomipramine: 50mg October-December 2016 

Vyvanse: 20mg on most days from December 2016-February 2017, 10mg on most days from February-December 2017, 5-10mg as needed afterward. Stopped Vyvanse April 2018.

Clonazepam: 0.25mg x3 February 2018-April 2018, 0.25mg x2 April-June 2018, 0.25mg x1 June-August 2018, tapered off 0.25mg over the course of 2 weeks.

Escitalopram: 10mg December 2016, 15mg January 2017, 20mg February-December 2017, 30mg January 2018, 40mg February-April; began taper end of April, 15mg mid-June 2018, rushed from 15-0mg from mid-June to late June 2018. Reinstated to 1mg August 2018, then 2mg then 5mg then 10mg over the course of 5 weeks. Decreased from 10mg to 8mg for 2 weeks, then from 8mg to 0mg when Vortioxetine was added. Reinstated within a few days to 2mg (in early November) and then dropped to 1mg in early December.

Vortioxetine: 5mg October-December 2018, tapered off over the course of 10 days after on it. 

December 7, December 2018 - June 22: Escitalopram 1mg.

Current: No psychoactive meds ever again.

 

Supplements: Mg2+ 600-800mg/day (most comes from HardyNutritionals DENs of which I take 12 capsules a day), 3000mg omega-3 oil, 1000mg vitamin C, tried 20+ other supplements before realizing that they are not effective for a destabilized central nervous system.

 

 

 

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Thanks for asking.  I am still struggling as bad.  I am sorry if you are in similar shoes.  I don't know if these head symptoms, especially the brain burning, are signs of permanent damage.  It is just not letting up.   

2006-15 Effexor on and off mostly on. Also tried drugs that didn't work; notriptyline, Celexa, Zoloft, Welbutrin, Abilify, Pristiq, Cymbalta. Weaned off Effexor for last time quickly (2015) - horrible depression, anxiety, and insomnia.
Remeron (2016) helped wd symptoms. 
2017 - tapered off Rem over a few mths. Horrible wd symptoms with insomnia. Reinstating Remeron fail. For wd insomnia tried: Trazodone, Elavil, Gabapentin, Seroquel, Doxepin, Valium. Failed. 2mg Ativan at bed intermittent use 4mth.
CT Ativan - off all meds June '17.  Recovered by Oct '17 - well for a yr.
Oct '18-now. Major stresses, drank alcohol. In hell -insomnia, dp/dr, head pressure, anhedonia, no emotions, blank mind.
May/June '19 - 16 doses Rem CT, 10 doses 2mg Ativan. CT

Recovered Oct 2020-June 2022 - fully functional, working.  Only left with head pressure.

Major stresses - mainly financial, living space, relationship - severe insomnia, severe anxiety, depression, dp/dr, emotional numbness, blank mind

Sept 2022 - for sleep - took 8 doses of 15mg Remeron, 3 doses of 7.5mg, 3 doses of 3.75mg, 3 doses of 1.875mg

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45 minutes ago, uncomfortablynumb said:

Thanks for asking.  I am still struggling as bad.  I am sorry if you are in similar shoes.  I don't know if these head symptoms, especially the brain burning, are signs of permanent damage.  It is just not letting up.   

Sorry to hear. Are you still hardly sleeping more than 2 hours a night?

 

 

Clomipramine: 50mg October-December 2016 

Vyvanse: 20mg on most days from December 2016-February 2017, 10mg on most days from February-December 2017, 5-10mg as needed afterward. Stopped Vyvanse April 2018.

Clonazepam: 0.25mg x3 February 2018-April 2018, 0.25mg x2 April-June 2018, 0.25mg x1 June-August 2018, tapered off 0.25mg over the course of 2 weeks.

Escitalopram: 10mg December 2016, 15mg January 2017, 20mg February-December 2017, 30mg January 2018, 40mg February-April; began taper end of April, 15mg mid-June 2018, rushed from 15-0mg from mid-June to late June 2018. Reinstated to 1mg August 2018, then 2mg then 5mg then 10mg over the course of 5 weeks. Decreased from 10mg to 8mg for 2 weeks, then from 8mg to 0mg when Vortioxetine was added. Reinstated within a few days to 2mg (in early November) and then dropped to 1mg in early December.

Vortioxetine: 5mg October-December 2018, tapered off over the course of 10 days after on it. 

December 7, December 2018 - June 22: Escitalopram 1mg.

Current: No psychoactive meds ever again.

 

Supplements: Mg2+ 600-800mg/day (most comes from HardyNutritionals DENs of which I take 12 capsules a day), 3000mg omega-3 oil, 1000mg vitamin C, tried 20+ other supplements before realizing that they are not effective for a destabilized central nervous system.

 

 

 

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I still am not sleeping much at all.  It is ridiculous that it is not getting better.  Have you read about insomnia lasting years or head pressure and burning?  I need some kind of reassurance that this is not permanent.  Went to a neurologist and they didn't do tests.  They just wanted to prescribe Topamax before doing any investigation.  Topamax sounds horrible if you read about it.  I am feeling so lost and defeated.

2006-15 Effexor on and off mostly on. Also tried drugs that didn't work; notriptyline, Celexa, Zoloft, Welbutrin, Abilify, Pristiq, Cymbalta. Weaned off Effexor for last time quickly (2015) - horrible depression, anxiety, and insomnia.
Remeron (2016) helped wd symptoms. 
2017 - tapered off Rem over a few mths. Horrible wd symptoms with insomnia. Reinstating Remeron fail. For wd insomnia tried: Trazodone, Elavil, Gabapentin, Seroquel, Doxepin, Valium. Failed. 2mg Ativan at bed intermittent use 4mth.
CT Ativan - off all meds June '17.  Recovered by Oct '17 - well for a yr.
Oct '18-now. Major stresses, drank alcohol. In hell -insomnia, dp/dr, head pressure, anhedonia, no emotions, blank mind.
May/June '19 - 16 doses Rem CT, 10 doses 2mg Ativan. CT

Recovered Oct 2020-June 2022 - fully functional, working.  Only left with head pressure.

Major stresses - mainly financial, living space, relationship - severe insomnia, severe anxiety, depression, dp/dr, emotional numbness, blank mind

Sept 2022 - for sleep - took 8 doses of 15mg Remeron, 3 doses of 7.5mg, 3 doses of 3.75mg, 3 doses of 1.875mg

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36 minutes ago, uncomfortablynumb said:

I still am not sleeping much at all.  It is ridiculous that it is not getting better.  Have you read about insomnia lasting years or head pressure and burning?  I need some kind of reassurance that this is not permanent.  Went to a neurologist and they didn't do tests.  They just wanted to prescribe Topamax before doing any investigation.  Topamax sounds horrible if you read about it.  I am feeling so lost and defeated.

Really sorry to see you suffering so much. I have all the severe cognitive symptoms, anhedonia, depersonalization, squeezing head pressure, burning brain, etc. I do get windows of improvements every now and then, although waves dominate 95% of the time. I did notice that if I sleep less than 6.5 hours, all of my symptoms are more severe. I can thus only imagine the havoc your brain has been experiencing given how sleep deprived you are. Have you had any slight improvements/windows of improved sleep? I know individuals that suffer protracted benzo withdrawal can go several years with minimal sleep then they recover and all their symptoms resolve as soon as their sleep is normalized. 

 

Regarding Topamax, the neurologist wanted to see if by numbing your neurons he could trigger sleep. However, all those drugs create dependence and worsen the quality of sleep as shown in Dr. Matthew Walker's (world-renowned sleep scientist) novel "Why We Sleep?"

 

Do you still take ativan? I have no doubt that this you are suffering from severe protracted withdrawal syndrome, with many symptoms exacerbated by lack of sleep which was either triggered by stress combined with intrinsic chemical, synaptic, and structural changes that can occur during withdrawal at any point in time, or the latter alone. 

 

I am confident that you will heal from this but it will likely take many more months.

 

How many hours of sleep do you get on average?

Clomipramine: 50mg October-December 2016 

Vyvanse: 20mg on most days from December 2016-February 2017, 10mg on most days from February-December 2017, 5-10mg as needed afterward. Stopped Vyvanse April 2018.

Clonazepam: 0.25mg x3 February 2018-April 2018, 0.25mg x2 April-June 2018, 0.25mg x1 June-August 2018, tapered off 0.25mg over the course of 2 weeks.

Escitalopram: 10mg December 2016, 15mg January 2017, 20mg February-December 2017, 30mg January 2018, 40mg February-April; began taper end of April, 15mg mid-June 2018, rushed from 15-0mg from mid-June to late June 2018. Reinstated to 1mg August 2018, then 2mg then 5mg then 10mg over the course of 5 weeks. Decreased from 10mg to 8mg for 2 weeks, then from 8mg to 0mg when Vortioxetine was added. Reinstated within a few days to 2mg (in early November) and then dropped to 1mg in early December.

Vortioxetine: 5mg October-December 2018, tapered off over the course of 10 days after on it. 

December 7, December 2018 - June 22: Escitalopram 1mg.

Current: No psychoactive meds ever again.

 

Supplements: Mg2+ 600-800mg/day (most comes from HardyNutritionals DENs of which I take 12 capsules a day), 3000mg omega-3 oil, 1000mg vitamin C, tried 20+ other supplements before realizing that they are not effective for a destabilized central nervous system.

 

 

 

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Hi All

 

Hoe you don’t mind me joining your thread. I’ve been going through hell (six months CT from amitriptyline). I can tick your symptoms in relation to insomnia and  particularly head tension/pressure/squeezing etc. The latter is probably the worst, as it contributes to insomnia at night and then communicating and functioning during the day. Sometimes pressure, sometimes numbness, sometimes pins and needles sensation. Pretty 24/7 now. 

 

Other main symptoms are worsening head tremor and nerve pain/numbness/pins and needles in both lower legs. Don’t think I saw these in your blog?

 

Hope things improve for you.

 

God bless.

 

 

 

Cymbalta 2007

Lyrica 2010

Venlafaxine 2010-2018

Amitriptyline October 2018-2019. (25, 50, 75, 100, 75, 50, 25)

CT 10 Sept 2019

Reinstate amitriptyline 5 mg 29 Oct 2019

Reinstate amitriptyline 2.5mg 19 Nov 2019

CT 24  Nov 2019

Vitamin D 16 Dec and Promethazine 25mg 16 Dec (one month only)

 

 

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  • 1 month later...

Unconfort, how is your sleep?

 

I getting 15 min sleep the last two days its horrible. My head and fingers keep jerking. 

May - october 2017 - Mirtazapine from 7.5 - 12mg mg for insomnia

May - october 2017 Lyrica 100mg a day.

October-november 2017 - both mirt and Lyrica, or one of them went paradoxical, exteme vertigo after Lyrica. Cut down Lyrica to 3x25mg a day, same vertigo, CT Lyrica. Insomnia developed severe on 12 MG mirtazapine, reduced to 7.5, still insomnia, reduced to 3.75 still.insomnia. CT mirt. 

November 2017 - present burning feet, pins and needles, muscle spasms, myoclonus limbs, head, bugs crawling my head burning hands, left side worst. Ears cracking sensation.

May 2019 - put on gabapentin 100mg 4xday to counteract insomnia

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Just recovered to baseline sleep. It was getting hard. Tried melatonin and it helped.

May - october 2017 - Mirtazapine from 7.5 - 12mg mg for insomnia

May - october 2017 Lyrica 100mg a day.

October-november 2017 - both mirt and Lyrica, or one of them went paradoxical, exteme vertigo after Lyrica. Cut down Lyrica to 3x25mg a day, same vertigo, CT Lyrica. Insomnia developed severe on 12 MG mirtazapine, reduced to 7.5, still insomnia, reduced to 3.75 still.insomnia. CT mirt. 

November 2017 - present burning feet, pins and needles, muscle spasms, myoclonus limbs, head, bugs crawling my head burning hands, left side worst. Ears cracking sensation.

May 2019 - put on gabapentin 100mg 4xday to counteract insomnia

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This is just not getting better.  Never sleep over 2hours and go days without.  Never feel sleepy still.  

 

Head pressure and brain burning has not changed at all.  

 

Also cannot feel any emotion at all.  Stuck with DP/DR. Just depressed and anxious.  Can't feel joy, laugh, cry.  

 

Other things that are less concerning, considering the above are awful, include tinnitus and I have become almost completely night blind.

 

I don't see too many people recovering from my set of symptoms.  It seems like if you have a burning brain with a lot of head pressure the chances of recovering go way down.  I took way too many drugs and have done too many cold turkeys.  

 

If anyone knows of anyone who has recovered from my symptoms please let me know. Not in a good place now.       

2006-15 Effexor on and off mostly on. Also tried drugs that didn't work; notriptyline, Celexa, Zoloft, Welbutrin, Abilify, Pristiq, Cymbalta. Weaned off Effexor for last time quickly (2015) - horrible depression, anxiety, and insomnia.
Remeron (2016) helped wd symptoms. 
2017 - tapered off Rem over a few mths. Horrible wd symptoms with insomnia. Reinstating Remeron fail. For wd insomnia tried: Trazodone, Elavil, Gabapentin, Seroquel, Doxepin, Valium. Failed. 2mg Ativan at bed intermittent use 4mth.
CT Ativan - off all meds June '17.  Recovered by Oct '17 - well for a yr.
Oct '18-now. Major stresses, drank alcohol. In hell -insomnia, dp/dr, head pressure, anhedonia, no emotions, blank mind.
May/June '19 - 16 doses Rem CT, 10 doses 2mg Ativan. CT

Recovered Oct 2020-June 2022 - fully functional, working.  Only left with head pressure.

Major stresses - mainly financial, living space, relationship - severe insomnia, severe anxiety, depression, dp/dr, emotional numbness, blank mind

Sept 2022 - for sleep - took 8 doses of 15mg Remeron, 3 doses of 7.5mg, 3 doses of 3.75mg, 3 doses of 1.875mg

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  • Moderator Emeritus

Hello, 

 

Your symptoms sound like very common symptoms (DP/DR, anxiety, despair, tinnitus...).

 

Almost all people here have gone through them, and Succes stories show us healing will come :)
 

https://www.survivingantidepressants.org/forum/28-success-stories-recovery-from-withdrawal/

 

 

I know how hard it can be, it is so hard to remember that it is only temporary while going through the worse of it. But it will. Slowly, gradually, healing is happening ❤️ 

2006 : 20mg Paxil+Bromazepam. 2008 : cold turkey of both. 2010 : Reinstatement 20mg Paxil + Bromazepam.

2014-June2017 : Switch from Bromazepam to Prazepam, slow taper to 0mg.

2018 to August 2019 : Paxil 20mg taper (3% every 15 days). 22 Aug 2019 updose to 10mg (was at 8.4mg).

25th Sept 2019 To April 2020 : found SA, holding at 10mg Paxil. 

April 2020 : Paxil 10mg to Prozac 7mg bridge. Details topic/21457

 

Current Supplements : magnesium citrate + fish oil

Current medication :

* 7pm Diazepam  : 0.85mg (15 Aug 2022) / 0.95 mg (24 April 2022) / 1mg Diazepam (since 29 Aug 2020)

* 8am Prozac : 6.16mg (25 oct 2022, feel awful, slight updose) / 6.08 mg (9 oct 2022) / 6.24mg (11 July 22) / 6.44mg (22 May 22) / 6.64mg (4 Nov 21) / 6.72mg (8 oct 21) / 6.8 mg (15 Sept 21)6.88mg (14 Aug 21)/ 6.92mg (23 Jun 21)

 

I am not a professional, I don't give medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

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  • 2 weeks later...

Unconfort, just wide awake as i AM writting this. My brain simply does not shut down. Tinitus on left side just horrible. Gabapentin sometimes work sometimes not. Having constant head jerks to the left right back, i seem like a stupid robot. Your persistence gives me hope to endure. You are a hero men. 

 

We will win this. We have to. 

May - october 2017 - Mirtazapine from 7.5 - 12mg mg for insomnia

May - october 2017 Lyrica 100mg a day.

October-november 2017 - both mirt and Lyrica, or one of them went paradoxical, exteme vertigo after Lyrica. Cut down Lyrica to 3x25mg a day, same vertigo, CT Lyrica. Insomnia developed severe on 12 MG mirtazapine, reduced to 7.5, still insomnia, reduced to 3.75 still.insomnia. CT mirt. 

November 2017 - present burning feet, pins and needles, muscle spasms, myoclonus limbs, head, bugs crawling my head burning hands, left side worst. Ears cracking sensation.

May 2019 - put on gabapentin 100mg 4xday to counteract insomnia

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Unconfort, i know it is hard, but can you recall what happened from june to on october 2017? What do you thing that lead you to recover on October 2017? Do you remember doing something different with the meds, tried anything unusual?

 

Or could it be something is interfering with your recovery? Could you have lyme? Remember Lyme is not diagnosable from blood tests,because they come negative most time? Did you ever had any marks in your skin? Ever had facial palsy in your life? What had lead you to take effexor in the first place? Depression can be a sign of infection «, a chronic infection like lyme or bartonella.  Dont give up to rule out every single cause in your entire life since you have born until now, you might find something unusual or something that doctors said to you are normal and you must live with it, dont trust them they might horribly wrong, in fact medical error is on of the main causes of death in the world, be carefull, if there another way, dont rely only on what everyone tells you, go out of the box and dont give up. Not everything is withdrawal, not everything is Lyme, not everything is infection, but it something for sure.

 

You could try NAC its tolerable and chelates metals from the body and it is used to detox liver toxicity in hospitals. But it has a repair purpose on the brain, it inhibits glutamante wish is the excitatory neurotransmiter in the brain. Research it and find studies about it. It even  modulates anxiety and is used for psychiatric disorders.

its not a drug, it even works as an antibiotic.

 

Please do your own research on it and make your decision, try something else. Dont give up.

 

 

May - october 2017 - Mirtazapine from 7.5 - 12mg mg for insomnia

May - october 2017 Lyrica 100mg a day.

October-november 2017 - both mirt and Lyrica, or one of them went paradoxical, exteme vertigo after Lyrica. Cut down Lyrica to 3x25mg a day, same vertigo, CT Lyrica. Insomnia developed severe on 12 MG mirtazapine, reduced to 7.5, still insomnia, reduced to 3.75 still.insomnia. CT mirt. 

November 2017 - present burning feet, pins and needles, muscle spasms, myoclonus limbs, head, bugs crawling my head burning hands, left side worst. Ears cracking sensation.

May 2019 - put on gabapentin 100mg 4xday to counteract insomnia

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May - october 2017 - Mirtazapine from 7.5 - 12mg mg for insomnia

May - october 2017 Lyrica 100mg a day.

October-november 2017 - both mirt and Lyrica, or one of them went paradoxical, exteme vertigo after Lyrica. Cut down Lyrica to 3x25mg a day, same vertigo, CT Lyrica. Insomnia developed severe on 12 MG mirtazapine, reduced to 7.5, still insomnia, reduced to 3.75 still.insomnia. CT mirt. 

November 2017 - present burning feet, pins and needles, muscle spasms, myoclonus limbs, head, bugs crawling my head burning hands, left side worst. Ears cracking sensation.

May 2019 - put on gabapentin 100mg 4xday to counteract insomnia

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It even helps to recover from brain injury:

 

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989181/

May - october 2017 - Mirtazapine from 7.5 - 12mg mg for insomnia

May - october 2017 Lyrica 100mg a day.

October-november 2017 - both mirt and Lyrica, or one of them went paradoxical, exteme vertigo after Lyrica. Cut down Lyrica to 3x25mg a day, same vertigo, CT Lyrica. Insomnia developed severe on 12 MG mirtazapine, reduced to 7.5, still insomnia, reduced to 3.75 still.insomnia. CT mirt. 

November 2017 - present burning feet, pins and needles, muscle spasms, myoclonus limbs, head, bugs crawling my head burning hands, left side worst. Ears cracking sensation.

May 2019 - put on gabapentin 100mg 4xday to counteract insomnia

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  • 2 months later...

How are you doing my friend? Tried NAC?  Hope you get well. Best of health.

May - october 2017 - Mirtazapine from 7.5 - 12mg mg for insomnia

May - october 2017 Lyrica 100mg a day.

October-november 2017 - both mirt and Lyrica, or one of them went paradoxical, exteme vertigo after Lyrica. Cut down Lyrica to 3x25mg a day, same vertigo, CT Lyrica. Insomnia developed severe on 12 MG mirtazapine, reduced to 7.5, still insomnia, reduced to 3.75 still.insomnia. CT mirt. 

November 2017 - present burning feet, pins and needles, muscle spasms, myoclonus limbs, head, bugs crawling my head burning hands, left side worst. Ears cracking sensation.

May 2019 - put on gabapentin 100mg 4xday to counteract insomnia

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  • 3 months later...

I actually did the remeron thing for about a month after panicking after my last dose of Prozac. I did not feel any help from it and then had to taper that down. In the end, for me it just seemed like it prolonged the taper process. I would love to be another month down the road free of this and in the rebuilding process. I don't have any opinions on whether or not it is a good idea. Just sharing my experience.

Paxil  2000 - 2002  Tried unsuccessfully to discontinue

2002 - 2010 A series of trial and error, Wellbutrin, Effexor and unsuccessful attempts to discontinue.  

2010 - 2017 Lexapro With several unsuccessful attempts to withdraw 

2012 - 2017 Lamictal Successfully withdrew Lamictal no problem

2017 - 2020 Switched to 40mg. Prozac to prepare try another Withdrawal. 

2020 - On 15mg Remeron for a few months during withdrawal

Completely off of Antidepressants since Sept. 2020

Klonipin as needed throughout the process. .25 mostly, some .5, some .125,  2 to 12 times per mo.

 

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Uncomfortablynumb, How are you my friend? Hope you are better

May - october 2017 - Mirtazapine from 7.5 - 12mg mg for insomnia

May - october 2017 Lyrica 100mg a day.

October-november 2017 - both mirt and Lyrica, or one of them went paradoxical, exteme vertigo after Lyrica. Cut down Lyrica to 3x25mg a day, same vertigo, CT Lyrica. Insomnia developed severe on 12 MG mirtazapine, reduced to 7.5, still insomnia, reduced to 3.75 still.insomnia. CT mirt. 

November 2017 - present burning feet, pins and needles, muscle spasms, myoclonus limbs, head, bugs crawling my head burning hands, left side worst. Ears cracking sensation.

May 2019 - put on gabapentin 100mg 4xday to counteract insomnia

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  • 1 month later...

Were ever you are my friend, you fought everyday, hope you still fighting, like you, my hope is starting to fade too. At least you were my hope, my friend. Everytime i saw your posts on how you coped so many days without sleep, i got encouraged to endure too, but now i have lost the hope for me too. 

 

I see you around were ever you are.

May - october 2017 - Mirtazapine from 7.5 - 12mg mg for insomnia

May - october 2017 Lyrica 100mg a day.

October-november 2017 - both mirt and Lyrica, or one of them went paradoxical, exteme vertigo after Lyrica. Cut down Lyrica to 3x25mg a day, same vertigo, CT Lyrica. Insomnia developed severe on 12 MG mirtazapine, reduced to 7.5, still insomnia, reduced to 3.75 still.insomnia. CT mirt. 

November 2017 - present burning feet, pins and needles, muscle spasms, myoclonus limbs, head, bugs crawling my head burning hands, left side worst. Ears cracking sensation.

May 2019 - put on gabapentin 100mg 4xday to counteract insomnia

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  • 1 year later...

@uncomfortablynumb

How are you feeling?

I have the same symptoms you were experiencing in your relapse! 

June-July -21 Zyprexa 2.5-7.5 mg 

July -21 Mianserin 20 mg four days

July-Aug -21 Valium 30 mg a day, tapred, return of symptoms 

Aug-Oct -21 Oxazepam Tapred from 10 mg x 3 to zero

Dec-Jan -21/22 On and off mirtazapine 15 mg. Kindling reaction?

March 8.-19. - Zopiclone 7.5 mg to combat insomnia 

March 20 - 5 mg valium because of akathisia and panic 

April 3. - 5 mg x 2

 

 
 

 

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Thank you so much for asking. Anxiety is intense!!! It's been 18 months since my last dose and I'm shocked that I'm still struggling as much as I am. Very limited in my daily activities and work even though I am faking my way through it and scraping by. I freak out and think I need to do something here, throw in the towel or something and then I pick myself up for another day. My husband says he sees improvement. I can totally keep going if I knew it was going to heal one day and give me freedom from this rollercoaster. My wishful thinking is that I wish I could see inside my body a map of where I was, where I am and if this is going somewhere that resembles healed. Like what thechell is going on in there to feel this way after over 2 years total. That for me is the challenge. I really need to work on recommitting to a vision that I am doing this because I intend to be healed and free one day. I'm feeling a little resigned right now. I would love to hear from others on how they stay positive in their vision and commitment. The upside is I'm still here taking it one day at a time and the tiny spark of hope is still outweighing the thought of going back. Blessings to you. Would love to hear how you are.  

Paxil  2000 - 2002  Tried unsuccessfully to discontinue

2002 - 2010 A series of trial and error, Wellbutrin, Effexor and unsuccessful attempts to discontinue.  

2010 - 2017 Lexapro With several unsuccessful attempts to withdraw 

2012 - 2017 Lamictal Successfully withdrew Lamictal no problem

2017 - 2020 Switched to 40mg. Prozac to prepare try another Withdrawal. 

2020 - On 15mg Remeron for a few months during withdrawal

Completely off of Antidepressants since Sept. 2020

Klonipin as needed throughout the process. .25 mostly, some .5, some .125,  2 to 12 times per mo.

 

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  • 6 months later...

Hi Everyone,

I was med-free and recovered (living on my own, trying different new jobs, building new relationship) from withdrawal for almost 2 years but early this year had stressful stuff happen (changing jobs and not finding a good placement and running out of my savings and some major relationship stresses).  I am not sure if this is a bout of depression/anxiety or a withdrawal setback.  It started again around July. I have been having the same symptoms of: depression, high anxiety, insomnia, depersonalization, derealization, emotional numbness, and blank mind.

Could anxiety and panic cause all this?  I am not working now and will have to go back home and live with my mom until I recover and find work/better work.  I had to tell my girlfriend we needed a break so I can figure this situation out.  It is all pretty horrible.  

 

I did something I regret, but I was desperate with severe sleep deprivation and got prescribed Remeron yet again (knowing I had a problem with it and withdrawals in the past).  I only took it at 15mg for 8 days, then 7.5mg for 3 days, then 3.75mg for 3 days, and then 1.875mg for 3 days.  Is this safe?  Or will I run into trouble?

 

 

2006-15 Effexor on and off mostly on. Also tried drugs that didn't work; notriptyline, Celexa, Zoloft, Welbutrin, Abilify, Pristiq, Cymbalta. Weaned off Effexor for last time quickly (2015) - horrible depression, anxiety, and insomnia.
Remeron (2016) helped wd symptoms. 
2017 - tapered off Rem over a few mths. Horrible wd symptoms with insomnia. Reinstating Remeron fail. For wd insomnia tried: Trazodone, Elavil, Gabapentin, Seroquel, Doxepin, Valium. Failed. 2mg Ativan at bed intermittent use 4mth.
CT Ativan - off all meds June '17.  Recovered by Oct '17 - well for a yr.
Oct '18-now. Major stresses, drank alcohol. In hell -insomnia, dp/dr, head pressure, anhedonia, no emotions, blank mind.
May/June '19 - 16 doses Rem CT, 10 doses 2mg Ativan. CT

Recovered Oct 2020-June 2022 - fully functional, working.  Only left with head pressure.

Major stresses - mainly financial, living space, relationship - severe insomnia, severe anxiety, depression, dp/dr, emotional numbness, blank mind

Sept 2022 - for sleep - took 8 doses of 15mg Remeron, 3 doses of 7.5mg, 3 doses of 3.75mg, 3 doses of 1.875mg

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  • Administrator

Merged with existing topic.

 

Hello, @uncomfortablynumb As you know, we don't provide support for people to ge remedicated, we have enough to do. We cannot tell you if you will run into trouble. You know how to taper off when you want to.

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

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At what point after stopping mirtazapine (30hr-ish half life) are you in clear of severe WD symptoms?

 

I stopped taking mirtazapine 3 days ago (after being on for 2wks) and so far have a bit of nausea, dizziness, and uptick of anxiety.  

I am wondering at what point I may be in the clear for avoiding severe withdrawal (extreme insomnia, worse head pressure etc.)?  I think I remember the severe insomnia almost came the first or second night after stopping mirtazapine the first time.  But since mirtazapine has such a long half life, is it possible to start experiencing severe withdrawal a week after cessation?  

 

I had healed for over 1.5 years and then insomnia (along with my other symptoms of past withdrawals) came back and broke me into taking the pills (have since told my psych I am really done with them this time because it is a dead end).  I was cursing myself after starting again.    

 

Edited by ChessieCat
added topic title before merging with intro topic

2006-15 Effexor on and off mostly on. Also tried drugs that didn't work; notriptyline, Celexa, Zoloft, Welbutrin, Abilify, Pristiq, Cymbalta. Weaned off Effexor for last time quickly (2015) - horrible depression, anxiety, and insomnia.
Remeron (2016) helped wd symptoms. 
2017 - tapered off Rem over a few mths. Horrible wd symptoms with insomnia. Reinstating Remeron fail. For wd insomnia tried: Trazodone, Elavil, Gabapentin, Seroquel, Doxepin, Valium. Failed. 2mg Ativan at bed intermittent use 4mth.
CT Ativan - off all meds June '17.  Recovered by Oct '17 - well for a yr.
Oct '18-now. Major stresses, drank alcohol. In hell -insomnia, dp/dr, head pressure, anhedonia, no emotions, blank mind.
May/June '19 - 16 doses Rem CT, 10 doses 2mg Ativan. CT

Recovered Oct 2020-June 2022 - fully functional, working.  Only left with head pressure.

Major stresses - mainly financial, living space, relationship - severe insomnia, severe anxiety, depression, dp/dr, emotional numbness, blank mind

Sept 2022 - for sleep - took 8 doses of 15mg Remeron, 3 doses of 7.5mg, 3 doses of 3.75mg, 3 doses of 1.875mg

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  • Moderator Emeritus

The effect of psychiatric drugs is cumulative.  What happened in the past may not be the same thing that will happen this time.

 

And sometimes withdrawal symptoms can be delayed.  When I cold turkeyed citalopram I felt really great for about 2 months and then became bedridden for 2.5 weeks with what felt a bit like the flu but it wasn't.  I was not able to eat and lost 8kgs in that time.  It wasn't until I found SA (after going onto Pristiq and then trying to get off it) that I realised that it was withdrawal.

 

What is helpful to understand is that it not to do with the half life of the drug and it "being out of your system".  When we take a psychiatric drug the brain makes adaptations to getting the drug.  And then when it is taken away the brain has to adapt to not getting the drug, in this case none at all.  Generally it can take as little as 1 month for the brain to fully adapt to getting a drug.  The process now needs to be reversed.  So being on it for 2 weeks your brain will have been part of the way there.  It will depend of how much your brain had adapted to getting the drug and how your nervous systems reacts to not getting the drug which will be affected by your past drug history.

 

You've been a member here 1 year longer than I have so I would have thought by now that you understand how it works.

 

Brain Remodelling
Video:  Healing From Antidepressants - Patterns of Recovery
What is Happening in Your Brain

* NO LONGER ACTIVE on SA *

MISSION ACCOMPLISHED:  (6 year taper)      0mg Pristiq  on 13th November 2021

ADs since ~1992:  25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq:  50mg 2012, 100mg beg 2013 (Serotonin Toxicity)  Tapering from Oct 2015 - 13 Nov 2021   LAST DOSE 0.0025mg

Post 0 updates start here    My tapering program     My Intro (goes to tapering graph)

 VIDEO:   Antidepressant Withdrawal Syndrome and its Management

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