Jump to content

Aspartame , Depression and SSRI's


Fresh
 Share

Recommended Posts

  • Moderator Emeritus

Food for Thought: Aspartame , Depression and SSRI's

By Melissa Melton

 

 

The eighties didn’t just bring us the magic of hot green biker shorts; it also gave us FDA approval of the artificial sweetener Aspartame and the antidepressant Prozac.

Three quick facts about Aspartame: it is the most widely abundant artificial sweetener on the grocery store shelves today, it took the U.S. Food and Drug Administration (FDA) over 20 years to finally approve it, and when it finally did get approved, it had not been tested on humans even once beforehand (although animal studies concluded the substance caused cancer, neurological issues, and literally ate holes in brain tissue).

Aspartame is 50 percent phenylalanine, 40 percent aspartic acid, and 10 percent methanol (yummy). It comes from genetically modified (GM) E. coli bacteria, and by “comes from”, I mean Aspartame is GM bacteria poop (super yummy). Aspartic acid is an excitotoxin, methanol is wood alcohol used in antifreeze, and too much of the amino acid phenylalanine in the brain can decrease serotonin levels over time, leading to chemical imbalances that can cause mood disorders and depression.

Why? Because serotonin is the neurotransmitter widely believed to contribute to an overall sense of happiness and well-being. Not only can serotonin influence moods and emotions, but it can effect sleep patterns and aggression too.

The FDA first approved Aspartame for use in soda in 1983, after a two-decade-long battle that only ended when President Ronald Reagan fired the FDA commissioner holding things up and put in a new guy that would essentiallyrubber stamp the sweetener for then-Searle Pharmaceutical CEO Donald Rumsfeld, a key player in the shadow government power structure. Searle sold $600 million bucks worth of the stuff in just the following year, and Rumsfeld later became the U.S. Secretary of Defense after he played a major role in Monsanto’s acquisition of Searle.

But did you catch the part before that? Too much phenylalanine, a key component in Aspartame, can decrease serotonin levels and lead to depression. What would one need if they were, say, suffering low serotonin levels that contributed to depression?

Oh why, a selective serotonin reuptake inhibitor (SSRI) of course!

The global pharmaceutical company with extensive Bush family ties, Eli Lilly, got its SSRI Prozac approved in 1987, and the drug first appeared on the market in 1988. In just two years’ time, Prozac became the “most prescribed” SSRI in the United States.

 

A 2010 U.S. Centers for Disease Control and Prevention study found that a fifth of the U.S. population drinks soda on any given day, and the second most popular soda is Diet Coke (with Aspartame). Four of the top ten sodas are diet and contain Aspartame. Today, one in ten Americans take SSRIs.

Nevermind that a multitude of studies have linked antidepressants to everything from birth defects (causing the FDA to place a black box warning on them) to increased suicidal tendencies (causing the FDA to update the initial black box warning to include an additional suicidal tendencies warning).

Problem: Does Aspartame cause depression?
ReactionStudies say it, in fact, can.
Solution: Antidepressants, please!

Hey, wait a minute. Is there a possible link between the best-selling artificial sweetener on the market today and the most widely-prescribed antidepressant in history?

Must be yet another coincidence, just like all of these people:

pharmagovvenn1.jpg

Food for thought.

Did You Know?

Donald Rumsfeld, former Searle CEO and Defense Secretary, sat on the board directors for Amylin Pharmaceuticals twice, and the second time was right before the company partnered with Eli Lilly. Rumsfeld ran the Pentagon under President George W. Bush, overseeing the Iraq War, while President George H. W. Bush was appointed to the Eli Lilly Board of Directors by the Quayle family after leaving his CIA Director post in the 1970.

1987-1997 pertofran , prothiaden , Prozac 1997-2002 Zoloft 2002-2004 effexor 2004-2010 Lexapro 40mg

2010-2012Cymbalta 120mg

Sept. 2012 -decreased 90mg in 6months. Care taken over by Dr Lucire in March 2013 , decreased last 30mg at 2mg per week over 3 months. July 21 , 2013- last dose of Cymbalta

Protracted withdrawal syndrome kicked in badly Jan.2014 Unrelenting akathisia until May 2014. Voluntary hosp. admission. Cocktail of Seroquel, Ativan and mirtazapine and I was well enough to go home after 14 days. Stopped all hosp. meds in next few months.

July 2014 felt v.depressed - couldn't stop crying. Started pristiq 50mg. Felt improvement within days and continued to improve, so stayed on 50mg for 8 months.

Began taper 28 Feb. 2015. Pristiq 50mg down to 45mg. Had one month of w/d symptoms. Started CES therapy in March. No w/d symptoms down to 30mg.

October 2015 , taking 25mg Pristiq. Capsules compounded with slow-release additive.

March 2016 , 21mg

Link to comment
Share on other sites

  • Moderator Emeritus

I became aware that phenylalanine was an issue when I began researching my MSG intolerance (I became hooked on Sour Cream and Onion Pringles).  Michael J Fox has been a big drinker of Diet Pepsi.

 MISSION ACCOMPLISHED:    13 November 2021 -  0mg Pristiq      

Woohoo!!!  Finally off Pristiq   

ADs since ~1992:  25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq:  50mg 2012, 100mg beg 2013 (Serotonin Toxicity)  Tapering from Oct 2015 - 13 Nov 2021   LAST DOSE 0.0025mg

My full tapering program     My Intro (goes to my tapering graph)    My website

PLEASE NOTE:  I am not a medical professional.  I provide information and make suggestions.  I do not provide tapering advice via PM.  Please post questions in your Introduction topic.  Please do not tag me for any reason.  I am an unpaid volunteer and assist members if I am able to and when I have the time.  Thank you for your understanding.

Mid Nov 2021 changed to low carb diet due to diabetes & cholesterol.  Lost 1/16 body weight, BP has reduced a lot. 

Links to my exercises and weights.  I also do 3 x 5.5 min with HIIT on exercise bike with 20 secs/min as fast as I can cycle.

Link to comment
Share on other sites

  • 1 month later...

Good gracious!  I knew it was crap but never knew this...is there any evidence to suggest that if someone quits diet coke over time there bodies will reverse the damage to their serotonin levels created by the diet coke?

1995 - 2015 antidepressants and antianxiety medicine
Multiple failed attempts to quit/taper anti d/anti anxiety meds since 2008

June 17, 2016 began prozac bridge to get off of effexor xr, stopped effexor xr on June 24, 2016, could not tolerate prozac due to severe side effects so I had to stop it  Currently...300 mg ER of lithium, 1 mg of estradiol, 60 mg propranolol ER, Fish oil 2 x a day, Magnesium Glycinate,  zinc, vitamin c, vitamin d, NAC

 

 

 

 

 

Link to comment
Share on other sites

  • Moderator Emeritus

If you find any articles relating to that Downtongirl , please post them here.

 

"When withdrawing from aspartame, people often report an array of different withdrawal effects. Many individuals though who withdraw from drinking diet soda end up dealing with caffeine withdrawal symptoms, which can have some similar effects to the discontinuation from aspartame."

 

Full article and discussion of some identified aspartame withdrawal symptoms is here http://mentalhealthdaily.com/2014/07/18/aspartame-withdrawal-symptoms-list-of-possibilities/

 

.

1987-1997 pertofran , prothiaden , Prozac 1997-2002 Zoloft 2002-2004 effexor 2004-2010 Lexapro 40mg

2010-2012Cymbalta 120mg

Sept. 2012 -decreased 90mg in 6months. Care taken over by Dr Lucire in March 2013 , decreased last 30mg at 2mg per week over 3 months. July 21 , 2013- last dose of Cymbalta

Protracted withdrawal syndrome kicked in badly Jan.2014 Unrelenting akathisia until May 2014. Voluntary hosp. admission. Cocktail of Seroquel, Ativan and mirtazapine and I was well enough to go home after 14 days. Stopped all hosp. meds in next few months.

July 2014 felt v.depressed - couldn't stop crying. Started pristiq 50mg. Felt improvement within days and continued to improve, so stayed on 50mg for 8 months.

Began taper 28 Feb. 2015. Pristiq 50mg down to 45mg. Had one month of w/d symptoms. Started CES therapy in March. No w/d symptoms down to 30mg.

October 2015 , taking 25mg Pristiq. Capsules compounded with slow-release additive.

March 2016 , 21mg

Link to comment
Share on other sites

There is a book about Aspertaine and it discusses addiction 

 

http://www.amazon.ca/Aspartame-Disease-An-Ignored-Epidemic/dp/1884243177

 

 

I searched it for the word addiction 

Sign in to view the search results.
 
 
 

I then searched the book for the word serotonin

Sign in to view the search results.
 
 

WARNING THIS WILL BE LONG
Had a car accident in 85
Codeine was the pain med when I was release from hosp continuous use till 89
Given PROZAC by a specialist to help with nerve pain in my leg 89-90 not sure which year
Was not told a thing about it being a psych med thought it was a pain killer no info about psych side effects I went nuts had hallucinations. As I had a head injury and was diagnosed with a concussion in 85 I was sent to a head injury clinic in 1990 five years after the accident. I don't think they knew I had been on prozac I did not think it a big deal and never did finish the bottle of pills. I had tests of course lots of them. Was put into a pain clinic and given amitriptyline which stopped the withdrawal but had many side effects. But I could sleep something I had not done in a very long time the pain lessened. My mother got cancer in 94 they switched my meds to Zoloft to help deal with this pressure as I was her main care giver she died in 96. I stopped zoloft in 96 had withdrawal was put on paxil went nutty quit it ct put on resperidol quit it ct had withdrawal was put on Effexor... 2years later celexa was added 20mg then increased to 40mg huge personality change went wild. Did too fast taper off Celexa 05 as I felt unwell for a long time prior... quit Effexor 150mg ct 07 found ****** 8 months into withdrawal learned some things was banned from there in 08 have kept learning since. there is really not enough room here to put my history but I have a lot of opinions about a lot of things especially any of the drugs mentioned above.
One thing I would like to add here is this tidbit ALL OPIATES INCREASE SEROTONIN it is not a huge jump to being in chronic pain to being put on an ssri/snri and opiates will affect your antidepressants and your thinking.

As I do not update much I will put my quit date Nov. 17 2007 I quit Effexor cold turkey. 

http://survivingantidepressants.org/index.php?/topic/1096-introducing-myself-btdt/

There is a crack in everything ..That's how the light gets in :)

Link to comment
Share on other sites

There is a documentary called Sweet misery 

http://topdocumentaryfilms.com/sweet-misery-a-poisoned-world/

 

I am not up to watching it and it is slammed here by some as being bunk I don't know but I do not use aspertame or msg. 

 

which brings me to an old flow chart I found long ago which I was going to work on and never did I looked at it again just now and it has a list of things that counter act glutamate:

Taurine,

Magnesium

Cocaine

Red Bull

CoQ10

Booze

Ice Cream

 

Rx drugs listed that counter act glutamate these are dopamine agonists

LDopa

Bromocripline

Cabergoline

 

and Singulair which is a Leukotriene Blocker

 

Valium we all know is a benzo right...they have it listed with Lunesta which I don't know about 

 

This is a chart and tricky for me to follow today... all these listed above in the flow chart are green... there are other  colour titles...

blue = Glutamate Blockers 

ibuprofen, baclofen, memantine, riluzole, tramado, tizanodine,haloperidal,benadryl,vitamin e,cinnamon, antihistamines, special K which is ketamine, nicotine 

 

pink = Glutamate Removers 

vitamin B6, is the only one listed note it made me depressed after a few days ... could barely lift my head 

 

grey = protects from neurotoxicity 

ibuprofen, niacin,orange juice, vitamin C, alpha-lipoic acid,idebenone, uric acid?

may be useful I took ibuprofen every morning for a long time when I woke with server head issues cement head and brain fog headache... lowest adult dose tried kid dose once ... grape don't do it. 

 

purple = aids glucose to energy pathway 

There are a few others this chart related to Autism 

http://www.msgtruth.org/NEWUNIFIEDTHEORY.pdf

WARNING THIS WILL BE LONG
Had a car accident in 85
Codeine was the pain med when I was release from hosp continuous use till 89
Given PROZAC by a specialist to help with nerve pain in my leg 89-90 not sure which year
Was not told a thing about it being a psych med thought it was a pain killer no info about psych side effects I went nuts had hallucinations. As I had a head injury and was diagnosed with a concussion in 85 I was sent to a head injury clinic in 1990 five years after the accident. I don't think they knew I had been on prozac I did not think it a big deal and never did finish the bottle of pills. I had tests of course lots of them. Was put into a pain clinic and given amitriptyline which stopped the withdrawal but had many side effects. But I could sleep something I had not done in a very long time the pain lessened. My mother got cancer in 94 they switched my meds to Zoloft to help deal with this pressure as I was her main care giver she died in 96. I stopped zoloft in 96 had withdrawal was put on paxil went nutty quit it ct put on resperidol quit it ct had withdrawal was put on Effexor... 2years later celexa was added 20mg then increased to 40mg huge personality change went wild. Did too fast taper off Celexa 05 as I felt unwell for a long time prior... quit Effexor 150mg ct 07 found ****** 8 months into withdrawal learned some things was banned from there in 08 have kept learning since. there is really not enough room here to put my history but I have a lot of opinions about a lot of things especially any of the drugs mentioned above.
One thing I would like to add here is this tidbit ALL OPIATES INCREASE SEROTONIN it is not a huge jump to being in chronic pain to being put on an ssri/snri and opiates will affect your antidepressants and your thinking.

As I do not update much I will put my quit date Nov. 17 2007 I quit Effexor cold turkey. 

http://survivingantidepressants.org/index.php?/topic/1096-introducing-myself-btdt/

There is a crack in everything ..That's how the light gets in :)

Link to comment
Share on other sites

B 12 was on the list but I was not sure so did not add it look yourself.

WARNING THIS WILL BE LONG
Had a car accident in 85
Codeine was the pain med when I was release from hosp continuous use till 89
Given PROZAC by a specialist to help with nerve pain in my leg 89-90 not sure which year
Was not told a thing about it being a psych med thought it was a pain killer no info about psych side effects I went nuts had hallucinations. As I had a head injury and was diagnosed with a concussion in 85 I was sent to a head injury clinic in 1990 five years after the accident. I don't think they knew I had been on prozac I did not think it a big deal and never did finish the bottle of pills. I had tests of course lots of them. Was put into a pain clinic and given amitriptyline which stopped the withdrawal but had many side effects. But I could sleep something I had not done in a very long time the pain lessened. My mother got cancer in 94 they switched my meds to Zoloft to help deal with this pressure as I was her main care giver she died in 96. I stopped zoloft in 96 had withdrawal was put on paxil went nutty quit it ct put on resperidol quit it ct had withdrawal was put on Effexor... 2years later celexa was added 20mg then increased to 40mg huge personality change went wild. Did too fast taper off Celexa 05 as I felt unwell for a long time prior... quit Effexor 150mg ct 07 found ****** 8 months into withdrawal learned some things was banned from there in 08 have kept learning since. there is really not enough room here to put my history but I have a lot of opinions about a lot of things especially any of the drugs mentioned above.
One thing I would like to add here is this tidbit ALL OPIATES INCREASE SEROTONIN it is not a huge jump to being in chronic pain to being put on an ssri/snri and opiates will affect your antidepressants and your thinking.

As I do not update much I will put my quit date Nov. 17 2007 I quit Effexor cold turkey. 

http://survivingantidepressants.org/index.php?/topic/1096-introducing-myself-btdt/

There is a crack in everything ..That's how the light gets in :)

Link to comment
Share on other sites

  • 2 years later...

See how damaging aspartame can be

 

http://www.sweetpoison.com/aspartame-information.html

Drug free Sep. 23 2017

2009 Mar.: lexapro 10mg for headache for 2 weeks.

2009-2012: on and off 1/4 to 1/3 of 10mg

2012 June--2013 Jan,: 1/4-1/3 of 10mg generic, bad jaw pain

2013 Jan-Mar: 10 mg generic. severe jaw and head pain;

2013 Mar--Aug. started tapering (liquid ever since) from 10 to 5 (one step) then gradually down to 2.25 mg by July. first ever panic attack, severe head/jaw pain

2013 Aug.: back to 2.75 mg; Nov: back to Brand Lex. 2.75mg -- 3mg,

2014 June: stopped PPI, head pressure/numbness. up-dosed 4.5mg, severe reaction mental symptoms added on

2014 Aug--2015 Aug: Micro taper down to 3.2mg, .025mg (<1%) cut holding 2-3 weeks.

2015 Aug 15th, Accidental one dose of 4.2mg. worsening brain non-functional, swollen head, body, coma like, DR

2016 Feb., started dosing 10am through 11 pm everyday 2/13--3.2mg, 3/15-- 2.9mg, 4/19-- 2.6mg, 6/26--2.2mg, 7/22 --1.9mg, 8/16--1.8mg,8/31--1.7m g, 9/13--1.6mg, 9/27--1.5mg, 10/8--1.4mg, 10/14--1.3mg, 11/1--1.2mg, 11/29--1.1mg, 12/12--1mg, 12/22--0.9mg

2017: 1/7--0.8mg, 1/15--0.7mg, 1/17--0.6mg, 1/20--0.52, 1/21--0.4mg, 1/22--0.26, 1/23--0.2, 2/13--0.13mg, 2/20--0.06mg, 3/18--0.13mg, 6/1--0.12mg, 7/6--0.1mg, 7/14--0.08mg, 8/17--0.04mg, 8/20--0.03mg, 8/28--0.02mg, 9/6--0.0205mg, 9/8--0.02mg, 9/17--0.015mg, 9/20--0.01mg, 9/21--0.0048mg, 9/22--0.0001mg,

Link to comment
Share on other sites

I thought I'd already responded to this, but apparently not.

 

About thirty years ago I noticed that if I had artificial sweeteners, I would get migraines.

2005 St John's Wort / 2006-2012 Lexapro 20mg, 2 failed attempts to stop, tapered over 4.5 months in early 2012

January 2013 started Sertraline, over time worked up to 100mg

July 2014 Sertraline dropped from 100mg to 75mg, held for six months, slower tapering until 2019 22 Dec 3.2mg

2020 Sertraline 19 Jan 3.1mg, 26 Jan 3.0mg; 1 Mar 2.9, 7 Mar 2.8, May (some drops here) 24 May 2.5, May 29 2.4, June 21 2.3, June 28 2.2mg,  July 4 2.1mg, July 24 (or maybe a bit before) 2mg, early Nov switched to home made suspension; 29 Nov 1.8mg; approx 25 Dec 1.6mg)

2021 Some time in about Jan/Feb realised my dosing was off and as probably on more like 1.8mg and possible mixing error in making suspension; doses after 10 Feb accurate; 10 Feb 1.6mg; 7 Mar 1.4

 

My thread here at SA: https://www.survivingantidepressants.org/topic/1775-bubbles/page/17/

CurrentSertraline: 7 Mar 1.4mg / Armour Thyroid / endless allergy meds, erg

 

 

Link to comment
Share on other sites

Good for you bubbles, so I hope you stopped putting the poison into your body since then

Drug free Sep. 23 2017

2009 Mar.: lexapro 10mg for headache for 2 weeks.

2009-2012: on and off 1/4 to 1/3 of 10mg

2012 June--2013 Jan,: 1/4-1/3 of 10mg generic, bad jaw pain

2013 Jan-Mar: 10 mg generic. severe jaw and head pain;

2013 Mar--Aug. started tapering (liquid ever since) from 10 to 5 (one step) then gradually down to 2.25 mg by July. first ever panic attack, severe head/jaw pain

2013 Aug.: back to 2.75 mg; Nov: back to Brand Lex. 2.75mg -- 3mg,

2014 June: stopped PPI, head pressure/numbness. up-dosed 4.5mg, severe reaction mental symptoms added on

2014 Aug--2015 Aug: Micro taper down to 3.2mg, .025mg (<1%) cut holding 2-3 weeks.

2015 Aug 15th, Accidental one dose of 4.2mg. worsening brain non-functional, swollen head, body, coma like, DR

2016 Feb., started dosing 10am through 11 pm everyday 2/13--3.2mg, 3/15-- 2.9mg, 4/19-- 2.6mg, 6/26--2.2mg, 7/22 --1.9mg, 8/16--1.8mg,8/31--1.7m g, 9/13--1.6mg, 9/27--1.5mg, 10/8--1.4mg, 10/14--1.3mg, 11/1--1.2mg, 11/29--1.1mg, 12/12--1mg, 12/22--0.9mg

2017: 1/7--0.8mg, 1/15--0.7mg, 1/17--0.6mg, 1/20--0.52, 1/21--0.4mg, 1/22--0.26, 1/23--0.2, 2/13--0.13mg, 2/20--0.06mg, 3/18--0.13mg, 6/1--0.12mg, 7/6--0.1mg, 7/14--0.08mg, 8/17--0.04mg, 8/20--0.03mg, 8/28--0.02mg, 9/6--0.0205mg, 9/8--0.02mg, 9/17--0.015mg, 9/20--0.01mg, 9/21--0.0048mg, 9/22--0.0001mg,

Link to comment
Share on other sites

Oh yes! I only had them - migraines and artificial sweeteners for about a year. I worked two shifts a week in a fast food place and staff were given 2 sodas per shift - I chose some with artificial sweeteners. I started to get migraines. I read somewhere that they were a trigger for migraine. I have avoided them since then and haven't had a migraine in over 30 years.

 

I know I've accidentally had some here and there - this recent push to demonise sugar has the unfortunate side effect of giving artificial sweeteners a health halo and sometimes they appear where not expected. Don't get me wrong - I don't think sugar is *good*, just for me artificial sweeteners are worse. Still, irregular and small intake doesn't seem to be enough to cause me migraines.

 

I discussed it with a doctor some time after that, who asked me if I'd noticed if all, or just some artificial sweeteners, had that effect. I said I didn't know, I'd just cut them all out. He said that was a good move. Nothing has ever caused me to regret that decision!

2005 St John's Wort / 2006-2012 Lexapro 20mg, 2 failed attempts to stop, tapered over 4.5 months in early 2012

January 2013 started Sertraline, over time worked up to 100mg

July 2014 Sertraline dropped from 100mg to 75mg, held for six months, slower tapering until 2019 22 Dec 3.2mg

2020 Sertraline 19 Jan 3.1mg, 26 Jan 3.0mg; 1 Mar 2.9, 7 Mar 2.8, May (some drops here) 24 May 2.5, May 29 2.4, June 21 2.3, June 28 2.2mg,  July 4 2.1mg, July 24 (or maybe a bit before) 2mg, early Nov switched to home made suspension; 29 Nov 1.8mg; approx 25 Dec 1.6mg)

2021 Some time in about Jan/Feb realised my dosing was off and as probably on more like 1.8mg and possible mixing error in making suspension; doses after 10 Feb accurate; 10 Feb 1.6mg; 7 Mar 1.4

 

My thread here at SA: https://www.survivingantidepressants.org/topic/1775-bubbles/page/17/

CurrentSertraline: 7 Mar 1.4mg / Armour Thyroid / endless allergy meds, erg

 

 

Link to comment
Share on other sites

 Share

×
×
  • Create New...

Important Information

Terms of Use Privacy Policy