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Chris60: Mirtazapine


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How do I come off mirtazipine.i've been taking 30mg daily for roughly 8 months, would like to stop but how do I do this gradually? I hear you should not just stop,you need to ween yourself off them.

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Hi Chris , I am also on mirtazapine ,about 6 months and want to come of it , I tried cutting from30 to 15mg and crashed really badly , this med has done nothing for me if anything made my depression worse , I wanted to stabilise a bit before withdrawing but as the med is not doing anything for me I don't think I will ever be stabilise , all I can say is go very slow in withdrawing ,there is very good info on here about withdrawing so read up up as much as you can , may I ask why you want to come of matazapine

2001 to jan 2015 Effexor 150 mg 

jan 2015 15 mg mirtazapine 20 mg quetiapine 

feb 2015 quetiapine stopped 

feb 2015 30 mg of citalopram added 

feb 2015 mirtazapine increased to 30 mg 

july 2015 citalopram stopped 

sept 2015 200mg of pregabalin 

jan 2017 mirtazapine stopped

jan 2017 20 mg fluoxetine

march 2017 all meds stopped 

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Hi Chris--  Welcome tot he group, I'm so glad you've gotten here before you started to reduce your dose.  It is much better to start out properly then to try and play catch up.  Mirtz  is one of the trickier ones to deal with, but done correctly there should be a minimum of fuss.  We have several threads of information that it would be good for you to take a look at:


Preparing to taper


Why taper by 10% of my dosage?


Tips for tapering off Remeron (mirtazapine)


That will get you started, give those a read and then come back and ask a lot of questions.


If you would please add a signature block it would really help us to see what is going on.




Also if you would please start a thread in the Introduction forum, you will get a lot more responses and you can use it for your journal and asking all the questions you'd like. 

20 years on Paxil starting at 20mg and working up to 40mg. Sept 2011 started 10% every 6 weeks taper (2.5% every week for 4 weeks then hold for 2 additional weeks), currently at 7.9mg. Oct 2011 CTed 15oz vodka a night, to only drinking 2 beers most nights, totally sober Feb 2013.

Since I wrote this I have continued to decrease my dose by 10% every 6 weeks (2.5% every week for 4 weeks and then hold for an additional 2 weeks). I added in an extra 6 week hold when I hit 10mg to let things settle out even more. When I hit 3mgpw it became hard to split the drop into 4 parts so I switched to dropping 1mgpw (pill weight) every week for 3 weeks and then holding for another 3 weeks.  The 3 + 3 schedule turned out to be too harsh so I cut back to dropping 1mgpw every 4 weeks which is working better.

Final Dose 0.016mg.     Current dose 0.000mg 04-15-2017


"It's also important not to become angry, no matter how difficult life is, because you can loose all hope if you can't laugh at yourself and at life in general."  Stephen Hawking

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