Jump to content

roxie tapering off risperidone .5 mg?


Recommended Posts

I am new to this group.  I have been on a psychotropic medication cocktail for several years, including:  clonazepam .5 mg which I tapered off of about 3 weeks ago; risperidone .5 mg (still want to taper this med); duloxetine 60 mg; and lamotrigine 200 mg.  I still have some withdrawal symptoms from the clonazepam, but am coping okay thus far.  I want to come off all the others too, but am wondering which one first, and also how to taper off .5 mg of risperidone. I tried cold turkey off risperidone a few days ago, and within 4 days, I had super withdrawal symptoms including irritability, anger, hostility, aggression, anxiety, to the point where I could not stand it anymore, so I went back on the .5 mg of risperidone last night and today I feel better with no withdrawal symptoms.  How does one taper off .5 mg of risperidone when the pill is so teensy that I cannot cut it, even with the pill splitter.  Does anyone know how to taper this drug?

Link to comment
  • Moderator Emeritus

Hi roxie , welcome to the site. Your post has been moved to the Introductions section. This is your

own personal thread to journal or ask questions. Please click FOLLOW at the top right so you receive

an email each time someone posts here.


We have all the information you need to taper off safely , so I'm going to point you in a few directions

and you have some reading ahead.


" clonazepam .5 mg which I tapered off of about 3 weeks ago"

This is huge accomplishment. Please don't make any further changes for at least 2 or 3 months so your

central nervous system can recover. As you found , things are fragile at the moment.


With regard to which drug to taper next , see "Taking multiple psych drugs? Which drug to taper first?"


We usually advise tapering the more activating drug first , which would be duloxetine. Holding the 0.5mg

respiradone may help keep things stable.


To taper from tiny doses like 0.5mg , you can make a liquid solution by dissolving you tablet in water

and using a syringe to draw up a precise amount. See http://survivingantidepressants.org/index.php?/topic/2693-how-to-make-a-liquid-from-tablets-or-capsules/


Please come back with questions. You've had a taste of how things can get bad very quickly , and we want

to help you avoid that.


It would be a big help if you can fill in your signature with a summary of your drug history. Please read



Best wishes , Fresh

1987-1997 pertofran , prothiaden , Prozac 1997-2002 Zoloft 2002-2004 effexor 2004-2010 Lexapro 40mg

2010-2012Cymbalta 120mg

Sept. 2012 -decreased 90mg in 6months. Care taken over by Dr Lucire in March 2013 , decreased last 30mg at 2mg per week over 3 months. July 21 , 2013- last dose of Cymbalta

Protracted withdrawal syndrome kicked in badly Jan.2014 Unrelenting akathisia until May 2014. Voluntary hosp. admission. Cocktail of Seroquel, Ativan and mirtazapine and I was well enough to go home after 14 days. Stopped all hosp. meds in next few months.

July 2014 felt v.depressed - couldn't stop crying. Started pristiq 50mg. Felt improvement within days and continued to improve, so stayed on 50mg for 8 months.

Began taper 28 Feb. 2015. Pristiq 50mg down to 45mg. Had one month of w/d symptoms. Started CES therapy in March. No w/d symptoms down to 30mg.

October 2015 , taking 25mg Pristiq. Capsules compounded with slow-release additive.

March 2016 , 21mg

Link to comment

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now
  • Create New...

Important Information

Terms of Use Privacy Policy