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Pokopen tapering duloxetine


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I've been tapering Duloxetine from Lupin Pharmaceuticals which come in a capsule of 5 mg mini tablets. Started from 60 mg, I took out one mini tablet at a time to 30 mg. but now withdrawal symptoms more apparent, I am switching to the bead counting using brand name Cymbalta.


My question is, how safe is mixing Lupin Pharmaceutical's duloxetine with brand name Cymbalta? In other word, how accurate is the actual potency of lupin's mini tablets? In theory, we can do as described in the original post, say, 5 mini tablets of Lupin's and 2 mg worth of brand name to create 27 mg. what I am worrying is that when its time to decrease one mini tablet using this method (e.g., 21 mg to 19 mg), is it possible to have a fluctuation in potency?


Does any of you have experience with this method? I'm sure it is safer to use brand name throughout, but mixing the mini tablet does save money. I want to know the ACTUAL experience of people using this method.



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  • 6 months later...
  • Administrator

Hello, Pokopen.


I am sorry this post was overlooked in the Cymbalta tapering topic. Some people feel a difference between the generic and brand name drugs, some do not.


How are you doing now?

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

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  • 1 year later...

Pokopen any update?

Thought for the day: Lets stand up, and let’s speak out , together. G Olsen

We have until the 14th. Feb 2018. 

URGENT REQUEST Please consider submitting  for the petition on Prescribed Drug Dependence and Withdrawal currently awaiting its third consideration at the Scottish Parliament. You don't even have to be from Scotland. By clicking on the link below you can read some of the previous submissions but be warned many of them are quite harrowing.


Please tell them about your problems taking and withdrawing from antidepressants and/or benzos.

Send by email to petitions@parliament.scot and quote PE01651 in the subject heading. Keep to a maximum of 3 sides of A4 and you can't name for legal reasons any doctor you have consulted. Tell them if you wish to remain anonymous. We need the numbers to help convince the committee members we are not isolated cases. You have until mid February. Thank you

Recovering paxil addict

None of the published articles shed light on what ssri's ... actually do or what their hazards might be. Healy 2013. 

This is so true, with anything you get on these drugs, dependance, tapering, withdrawal symptoms, side effects, just silent. And if there is something mentioned then their is a serious disconnect between what is said and reality! 

  "Every time I read of a multi-person shooting, I always presume that person had just started a SSRI or had just stopped."  Dr Mosher. Me too! 

Over two decades later, the number of antidepressant prescriptions a year is slightly more than the number of people in the Western world. Most (nine out of 10) prescriptions are for patients who faced difficulties on stopping, equating to about a tenth of the population. These patients are often advised to continue treatment because their difficulties indicate they need ongoing treatment, just as a person with diabetes needs insulin. Healy 2015

I believe the ssri era will soon stand as one of the most shameful in the history of medicine. Healy 2015

Let people help people ... in a natural, kind, non-addictive (and non-big pharma) way. J Broadley 2017



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