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Staz: Poly drugged & trying to get drug free


Staz

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Hi everyone,

I've been on and off a slew of drugs since having depression starting in March 2016. I'm in the U.K. so was treated by our NHS who initially put me on mirtazapine then when that didn't work they introduced me to prozac at 25mg and my anxiety went sky high. I'd been on and off prozac several times in the last 20 years but the reaction was horrific. To calm me down they put me on Diazepam at 15mg until I became so ill I was hospitalised for 2 weeks in May 2016. Prozac was withdrawn and replaced by Escitalopram which gave me the same severe reaction. To counter this I was put on Lyrica at 300mg and within 10 weeks became suicidal so I've just finished a taper from lyrica and am still suffering withdrawals after 8 weeks off the med. To try and counter my increasing depression lofepramine was prescribed along with Quetiapine at 150mg. The lofepramine did nothing so I tapered off of that but the quetiapine was kept in place by my shrink. My Lyrrica withdrawal was painful and my shrink added Dosulepin as an A/D. All this time I was kept on diazepam.

I'm now trying to untangle this mess and am suffering badly with depression and anxiety and none of my medication appears to be helping. I've made the decision to get off of as many meds as I can and am unsure of the order in which to reduce them. I feel I've been the victim of psychiatry and any advice would be appreciated.

Dosulepin 75mg 1996 - 1997 tapered off no problem - Prozac sporadic use between 1995 and 2011 usually 9 months then off.

Mirtazapine 2015 tapered off after 4 months no problem -Prozac 20mg 2012-2015 tapered off no problems

Prozac 20mg April 2016-May 2016 stopped ct after 4 weeks due to adverse reaction I believe to be serotnin toxicity due to mirtazapine interaction

Escitlopram 10 mg May 2016 - cut to 5mg May 2016  stopped ct November 2016 no W/d's noted

Lyrica 300mg May 2016 - July 2017 - Taper from Jan to Jul 17 awful taper.

Lofepramine 150mg  November 2016 - January 2017 Swift w/d as it didn't work

Quetiapine 75mg November 2016 changed to 150 XL May2017 changed to 150mg IR July 2017 reduced to in 25mg steps from July to 50mg Oct 17. 37.5mg 12th Nov 17 - 35mg 20 Nov 17 - 30mg 22 Nov 17 - 25mg 24 Nov 17 dropped to 20mg Dec 17, 15mg Jan 18. Current taken at bedtime.

Quetiapine dropped Jan 17th 2018.

Dosulepin 75mg May 2017 - increased in 25mg steps to 175mg Oct 17 Reduced to 150mg Nov 17 current taken at bedtime

Diazepam 15mg May 2016 - c/t'd by shrink after 6 weeks. Reinstated at 12mg after 4 weeks June 16 - current 4mg 3 times a day morning, 2.30pm and bedtime.

Mirtazapine 15mg since March 2015 - current - pooped out within 4 weeks

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  • ChessieCat changed the title to Staz: Poly drugged & trying to get drug free
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  • Moderator Emeritus

Staz -- Welcome to Surviving Antidepressants (SA)

 

You've been through a lot in the 17 months.  Unfortunately sometimes a drug that was previously effective or neutral can cause a problem at a later time. It's possible that either your exposure to mirtazapine or the way it interacted with prozac sensitized your CNS (central nervous system).

 

Thank you for posting a clear signature.  One thing I'd like to confirm -- are you still taking mirtazapine? Rereading your post and your signature, I'm not 100% certain. Also, am I correct in assuming that your doses of quetiapine, dosulepin and diazepam haven't changed since you started taking them?  If that's incorrect, please add the date you started your current dose to the relevant line in your signature.

 

Tapering off a medication in 8 weeks can be a painful experience for many if not most people, even if the drug was having negative effects.  Our approach to discontinuing medications is a conservative, harm-reduction approach: decrease ONLY one drug at a time by reducing dose by no more than 10% once per month. You can read more about that in these topics:

Before you begin tapering -- what you need to know.

Why taper by 10% of my dosage?.

 

You ask a very good question about where to start when you're taking more than one drug.  This discussion has suggestions about that:

Taking multiple drugs? Which to taper first.

 

Here are our topics relevant to your medications:

Tips for tapering off Remeron (mirtazapine)

Tips for tapering off Seroquel (quetiapine)

Members-only benzo forum -- tapering benzos like diazepam is different from other psychiatric medications so we have a special forum for those discussions

 

This is YOUR introduction topic -- the place for you to ask questions, record symptoms, share your progress, and connect with other members of the SA community.

 

I hope you'll find the information in the SA forums helpful for your situation. I'm sorry that you are in the position that you need the information, but am glad that you found us.

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.
1997-1999 Effexor; 2002-2005 Effexor XR 37.5 mg linear taper, dropping same #beads/week with bad results

Cymbalta 60 mg 2012 - 2015; 2016: 20 mg to 7 mg exact doses and dates in this post; 2017: 6.3 mg to  0.0 mg  Aug. 12; details here


scallywag's Introduction
Online spreadsheet for dose taper calculations and nz11's THE WORKS spreadsheet

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Hi Scallywag,

Yes I'm still on mirtazapine at 15mg. My dose of quetiapine was changed from 75mg to 150mg MR 3 months ago but has not been changed back to 150mg IR. Sorry if I didn't make this clear in my profile. I will amend it.

Thank you for the information and links you've provided.

Dosulepin 75mg 1996 - 1997 tapered off no problem - Prozac sporadic use between 1995 and 2011 usually 9 months then off.

Mirtazapine 2015 tapered off after 4 months no problem -Prozac 20mg 2012-2015 tapered off no problems

Prozac 20mg April 2016-May 2016 stopped ct after 4 weeks due to adverse reaction I believe to be serotnin toxicity due to mirtazapine interaction

Escitlopram 10 mg May 2016 - cut to 5mg May 2016  stopped ct November 2016 no W/d's noted

Lyrica 300mg May 2016 - July 2017 - Taper from Jan to Jul 17 awful taper.

Lofepramine 150mg  November 2016 - January 2017 Swift w/d as it didn't work

Quetiapine 75mg November 2016 changed to 150 XL May2017 changed to 150mg IR July 2017 reduced to in 25mg steps from July to 50mg Oct 17. 37.5mg 12th Nov 17 - 35mg 20 Nov 17 - 30mg 22 Nov 17 - 25mg 24 Nov 17 dropped to 20mg Dec 17, 15mg Jan 18. Current taken at bedtime.

Quetiapine dropped Jan 17th 2018.

Dosulepin 75mg May 2017 - increased in 25mg steps to 175mg Oct 17 Reduced to 150mg Nov 17 current taken at bedtime

Diazepam 15mg May 2016 - c/t'd by shrink after 6 weeks. Reinstated at 12mg after 4 weeks June 16 - current 4mg 3 times a day morning, 2.30pm and bedtime.

Mirtazapine 15mg since March 2015 - current - pooped out within 4 weeks

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Hi,

I'd like some advice please on which drug to taper first form my cocktail as shown below. I've just managed to get off of Lyrica after 10 months on it and despite all my meds I'm very depressed and anxious and having suicidal idealisation. Could this be part of the Lyrica w/d and when and which med should I tackle first. I should say I'm not psychotic and my Dr put me on seroquel as the A/D lofepramine was causing me to lose sleep. Due to no change in my condition my Dr upped my seroquel from 75mg to 150mg nightly and that has failed to work as well.

Any thoughts would be appreciated.

Staz

Dosulepin 75mg 1996 - 1997 tapered off no problem - Prozac sporadic use between 1995 and 2011 usually 9 months then off.

Mirtazapine 2015 tapered off after 4 months no problem -Prozac 20mg 2012-2015 tapered off no problems

Prozac 20mg April 2016-May 2016 stopped ct after 4 weeks due to adverse reaction I believe to be serotnin toxicity due to mirtazapine interaction

Escitlopram 10 mg May 2016 - cut to 5mg May 2016  stopped ct November 2016 no W/d's noted

Lyrica 300mg May 2016 - July 2017 - Taper from Jan to Jul 17 awful taper.

Lofepramine 150mg  November 2016 - January 2017 Swift w/d as it didn't work

Quetiapine 75mg November 2016 changed to 150 XL May2017 changed to 150mg IR July 2017 reduced to in 25mg steps from July to 50mg Oct 17. 37.5mg 12th Nov 17 - 35mg 20 Nov 17 - 30mg 22 Nov 17 - 25mg 24 Nov 17 dropped to 20mg Dec 17, 15mg Jan 18. Current taken at bedtime.

Quetiapine dropped Jan 17th 2018.

Dosulepin 75mg May 2017 - increased in 25mg steps to 175mg Oct 17 Reduced to 150mg Nov 17 current taken at bedtime

Diazepam 15mg May 2016 - c/t'd by shrink after 6 weeks. Reinstated at 12mg after 4 weeks June 16 - current 4mg 3 times a day morning, 2.30pm and bedtime.

Mirtazapine 15mg since March 2015 - current - pooped out within 4 weeks

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  • Moderator Emeritus

Staz, because you're still having symptoms from the RAPID Lyrica discontinuation, we'd suggest EITHER holding steady with your current medications and doses OR possibly reinstating a very, very small dose of Lyrica to see if it eases your symptoms.

 

What is your symptom pattern?  Please keep notes on paper of your symptoms and the times of your dose(s). This post has a useful format for a daily log:

Take notes of doses and symptoms.

 

You can either post those notes each day for a few days (3-4) or post 3-4 days worth of notes all at once in a single post.

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.
1997-1999 Effexor; 2002-2005 Effexor XR 37.5 mg linear taper, dropping same #beads/week with bad results

Cymbalta 60 mg 2012 - 2015; 2016: 20 mg to 7 mg exact doses and dates in this post; 2017: 6.3 mg to  0.0 mg  Aug. 12; details here


scallywag's Introduction
Online spreadsheet for dose taper calculations and nz11's THE WORKS spreadsheet

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6 hours ago, scallywag said:

Staz, because you're still having symptoms from the RAPID Lyrica discontinuation, we'd suggest EITHER holding steady with your current medications and doses OR possibly reinstating a very, very small dose of Lyrica to see if it eases your symptoms.

 

What is your symptom pattern?  Please keep notes on paper of your symptoms and the times of your dose(s). This post has a useful format for a daily log:

Take notes of doses and symptoms.

 

You can either post those notes each day for a few days (3-4) or post 3-4 days worth of notes all at once in a single post.

Ok thanks Scallywag. I will hold any further tapers until my Lyrica w/d's stop. I don't have the option of reinstating the Lyrica as my shrink doesn't believe in w/d's carrying on for long periods after stopping drugs and I've not got any spare tablets left over.

Staz

Dosulepin 75mg 1996 - 1997 tapered off no problem - Prozac sporadic use between 1995 and 2011 usually 9 months then off.

Mirtazapine 2015 tapered off after 4 months no problem -Prozac 20mg 2012-2015 tapered off no problems

Prozac 20mg April 2016-May 2016 stopped ct after 4 weeks due to adverse reaction I believe to be serotnin toxicity due to mirtazapine interaction

Escitlopram 10 mg May 2016 - cut to 5mg May 2016  stopped ct November 2016 no W/d's noted

Lyrica 300mg May 2016 - July 2017 - Taper from Jan to Jul 17 awful taper.

Lofepramine 150mg  November 2016 - January 2017 Swift w/d as it didn't work

Quetiapine 75mg November 2016 changed to 150 XL May2017 changed to 150mg IR July 2017 reduced to in 25mg steps from July to 50mg Oct 17. 37.5mg 12th Nov 17 - 35mg 20 Nov 17 - 30mg 22 Nov 17 - 25mg 24 Nov 17 dropped to 20mg Dec 17, 15mg Jan 18. Current taken at bedtime.

Quetiapine dropped Jan 17th 2018.

Dosulepin 75mg May 2017 - increased in 25mg steps to 175mg Oct 17 Reduced to 150mg Nov 17 current taken at bedtime

Diazepam 15mg May 2016 - c/t'd by shrink after 6 weeks. Reinstated at 12mg after 4 weeks June 16 - current 4mg 3 times a day morning, 2.30pm and bedtime.

Mirtazapine 15mg since March 2015 - current - pooped out within 4 weeks

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  • Moderator Emeritus

You can get a prescription from any doctor, it doesn't have to be a psychiatrist.

 

How do you talk to a doctor about tapering and withdrawal?


What should I expect from my doctor about withdrawal symptoms?

Please DO NOT TAG me - thank you

PLEASE NOTE:  I am not a medical professional.  I provide information and make suggestions. 

  MISSION ACCOMPLISHED:    (6 year taper)      0mg Pristiq      on 13th November 2021

ADs since ~1992:  25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq:  50mg 2012, 100mg beg 2013 (Serotonin Toxicity)  Tapering from Oct 2015 - 13 Nov 2021   LAST DOSE 0.0025mg

Post 0 updates start here    My tapering program     My Intro (goes to tapering graph)

 VIDEO:   Antidepressant Withdrawal Syndrome and its Management

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My Dr won't prescribe anything with out my shrinks say so ChessieCat. That's the way it works in the UK.

 

Dosulepin 75mg 1996 - 1997 tapered off no problem - Prozac sporadic use between 1995 and 2011 usually 9 months then off.

Mirtazapine 2015 tapered off after 4 months no problem -Prozac 20mg 2012-2015 tapered off no problems

Prozac 20mg April 2016-May 2016 stopped ct after 4 weeks due to adverse reaction I believe to be serotnin toxicity due to mirtazapine interaction

Escitlopram 10 mg May 2016 - cut to 5mg May 2016  stopped ct November 2016 no W/d's noted

Lyrica 300mg May 2016 - July 2017 - Taper from Jan to Jul 17 awful taper.

Lofepramine 150mg  November 2016 - January 2017 Swift w/d as it didn't work

Quetiapine 75mg November 2016 changed to 150 XL May2017 changed to 150mg IR July 2017 reduced to in 25mg steps from July to 50mg Oct 17. 37.5mg 12th Nov 17 - 35mg 20 Nov 17 - 30mg 22 Nov 17 - 25mg 24 Nov 17 dropped to 20mg Dec 17, 15mg Jan 18. Current taken at bedtime.

Quetiapine dropped Jan 17th 2018.

Dosulepin 75mg May 2017 - increased in 25mg steps to 175mg Oct 17 Reduced to 150mg Nov 17 current taken at bedtime

Diazepam 15mg May 2016 - c/t'd by shrink after 6 weeks. Reinstated at 12mg after 4 weeks June 16 - current 4mg 3 times a day morning, 2.30pm and bedtime.

Mirtazapine 15mg since March 2015 - current - pooped out within 4 weeks

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  • Moderator Emeritus

Staz,  what you're looking for with respect to your symptoms is stability -- no major swings within a day or from one day to the next. It may be that symptoms lighten and stop, or it may be a kinda-rotten-everyday-normal.  That's where a symptoms log becomes important; it's too easy to forget what has actually happened.

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.
1997-1999 Effexor; 2002-2005 Effexor XR 37.5 mg linear taper, dropping same #beads/week with bad results

Cymbalta 60 mg 2012 - 2015; 2016: 20 mg to 7 mg exact doses and dates in this post; 2017: 6.3 mg to  0.0 mg  Aug. 12; details here


scallywag's Introduction
Online spreadsheet for dose taper calculations and nz11's THE WORKS spreadsheet

Link to comment

It's rotten every day kind of normal Scallywag. Minor variations only I'm afraid. I've forgotten what feeling happiness and joy is like. My life has been 18 months of drugs hell. It's like living in a horror movie day after day every time I wake up.

Dosulepin 75mg 1996 - 1997 tapered off no problem - Prozac sporadic use between 1995 and 2011 usually 9 months then off.

Mirtazapine 2015 tapered off after 4 months no problem -Prozac 20mg 2012-2015 tapered off no problems

Prozac 20mg April 2016-May 2016 stopped ct after 4 weeks due to adverse reaction I believe to be serotnin toxicity due to mirtazapine interaction

Escitlopram 10 mg May 2016 - cut to 5mg May 2016  stopped ct November 2016 no W/d's noted

Lyrica 300mg May 2016 - July 2017 - Taper from Jan to Jul 17 awful taper.

Lofepramine 150mg  November 2016 - January 2017 Swift w/d as it didn't work

Quetiapine 75mg November 2016 changed to 150 XL May2017 changed to 150mg IR July 2017 reduced to in 25mg steps from July to 50mg Oct 17. 37.5mg 12th Nov 17 - 35mg 20 Nov 17 - 30mg 22 Nov 17 - 25mg 24 Nov 17 dropped to 20mg Dec 17, 15mg Jan 18. Current taken at bedtime.

Quetiapine dropped Jan 17th 2018.

Dosulepin 75mg May 2017 - increased in 25mg steps to 175mg Oct 17 Reduced to 150mg Nov 17 current taken at bedtime

Diazepam 15mg May 2016 - c/t'd by shrink after 6 weeks. Reinstated at 12mg after 4 weeks June 16 - current 4mg 3 times a day morning, 2.30pm and bedtime.

Mirtazapine 15mg since March 2015 - current - pooped out within 4 weeks

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On 9/13/2017 at 3:13 AM, scallywag said:

Staz,  what you're looking for with respect to your symptoms is stability -- no major swings within a day or from one day to the next. It may be that symptoms lighten and stop, or it may be a kinda-rotten-everyday-normal.  That's where a symptoms log becomes important; it's too easy to forget what has actually happened.

It's rotten every day kind of normal Scallywag. Minor variations only I'm afraid. I've forgotten what feeling happiness and joy is like. My life has been 18 months of drugs hell. It's like living in a horror movie day after day every time I wake up

Dosulepin 75mg 1996 - 1997 tapered off no problem - Prozac sporadic use between 1995 and 2011 usually 9 months then off.

Mirtazapine 2015 tapered off after 4 months no problem -Prozac 20mg 2012-2015 tapered off no problems

Prozac 20mg April 2016-May 2016 stopped ct after 4 weeks due to adverse reaction I believe to be serotnin toxicity due to mirtazapine interaction

Escitlopram 10 mg May 2016 - cut to 5mg May 2016  stopped ct November 2016 no W/d's noted

Lyrica 300mg May 2016 - July 2017 - Taper from Jan to Jul 17 awful taper.

Lofepramine 150mg  November 2016 - January 2017 Swift w/d as it didn't work

Quetiapine 75mg November 2016 changed to 150 XL May2017 changed to 150mg IR July 2017 reduced to in 25mg steps from July to 50mg Oct 17. 37.5mg 12th Nov 17 - 35mg 20 Nov 17 - 30mg 22 Nov 17 - 25mg 24 Nov 17 dropped to 20mg Dec 17, 15mg Jan 18. Current taken at bedtime.

Quetiapine dropped Jan 17th 2018.

Dosulepin 75mg May 2017 - increased in 25mg steps to 175mg Oct 17 Reduced to 150mg Nov 17 current taken at bedtime

Diazepam 15mg May 2016 - c/t'd by shrink after 6 weeks. Reinstated at 12mg after 4 weeks June 16 - current 4mg 3 times a day morning, 2.30pm and bedtime.

Mirtazapine 15mg since March 2015 - current - pooped out within 4 weeks

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  • 1 month later...

After many changes of meds to try and control my depression by shrink has suggested adding to those meds I already take. He wants to add either Lithium or lamotrigine. The other options are to take me off my dosulepin and try another a/d called aglomelatine or just taper off of diazepam and slowly remove all the other meds. I don't feel strong enough to cope atm and each day is endless agony. I've resorted to having a couple of beers an evening to try and get my mind to slow down but I know I can't rely on that and will create a bigger problem for myself so I'm cutting that out.

 

Does anyone have any experience with Lamotrigene or could offer any advice as it seems counter intuitive to add yet another med to my cocktail but I've read it works for treatment resistant depression for some? Any advice or views would be greatly appreciated.

Staz.

Dosulepin 75mg 1996 - 1997 tapered off no problem - Prozac sporadic use between 1995 and 2011 usually 9 months then off.

Mirtazapine 2015 tapered off after 4 months no problem -Prozac 20mg 2012-2015 tapered off no problems

Prozac 20mg April 2016-May 2016 stopped ct after 4 weeks due to adverse reaction I believe to be serotnin toxicity due to mirtazapine interaction

Escitlopram 10 mg May 2016 - cut to 5mg May 2016  stopped ct November 2016 no W/d's noted

Lyrica 300mg May 2016 - July 2017 - Taper from Jan to Jul 17 awful taper.

Lofepramine 150mg  November 2016 - January 2017 Swift w/d as it didn't work

Quetiapine 75mg November 2016 changed to 150 XL May2017 changed to 150mg IR July 2017 reduced to in 25mg steps from July to 50mg Oct 17. 37.5mg 12th Nov 17 - 35mg 20 Nov 17 - 30mg 22 Nov 17 - 25mg 24 Nov 17 dropped to 20mg Dec 17, 15mg Jan 18. Current taken at bedtime.

Quetiapine dropped Jan 17th 2018.

Dosulepin 75mg May 2017 - increased in 25mg steps to 175mg Oct 17 Reduced to 150mg Nov 17 current taken at bedtime

Diazepam 15mg May 2016 - c/t'd by shrink after 6 weeks. Reinstated at 12mg after 4 weeks June 16 - current 4mg 3 times a day morning, 2.30pm and bedtime.

Mirtazapine 15mg since March 2015 - current - pooped out within 4 weeks

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  • Moderator Emeritus

Hi Staz, I've moved your recent post back into your introduction topic and would ask that you post all of your questions there.  We have a policy of one topic per member and it is best to keep all of your information in one place.  I just noticed that you increased your Dosulepin dose from 75mg to 175mg ... and are now wanting to add another drug ... are you planning on tapering off of your medication or are you looking to find a medication that will help with your depression?  I am confused as to what you are trying to do?

 

Current Prescription Drugs for Hypothyroidism:  Synthroid 100mcg / Cytomel 5mcg (15 years Pristiq/Effexor)

Tapering Schedule
September 15, 2016 - switched from Pristiq 50mg to Effexor XR 75mg; November 10, 2016 - reduced to 67.5 Effexor XR
December 9, 2016 - reduced 60.75
January 5, 2017 - reduced 54.67
January 30, 2017 - reduced to 49.0
February 20, 2017 - reduced to 44.0 
May 20, 2017 - reduced to 40.25 (holding for additional month due to late onset of withdrawal symptoms after this taper)
July 17, 2017 - reduced to 38.24
August 15, 2017 - reduced to 37.5 (50% of my original dose)

October 15, 2017 - reduced to 35.6

November 12, 2017 - reduced to 33.8
December 15, 2017 - up-dose to 35.6
December 28, 2017 - up-dose to 37.5

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Sorry baroquep.

I'm just looking at the options my shrink has given me. My dosulepin TCA has been increased from 75mg in May to 175mg in October and has given me no benefit so the options are to leave everything as is and add a mood stabiliser as per my post or come off of dosulepin and add in another a/d called aglomelatine. After 18 months of not responding to treatments I'm really at my wits end and can't see an end to my suffering.

The odd thing is I always responded to prozac but when this episode started I was put on mirt then that failed after a few weeks and prozac re introduced. I nearly went mad with anxiety so the prozac was stopped after 21 days and the escitalopram added. Same result and down the poly drugged trail I went. My depression wasn't this bad before the meds.

Dosulepin 75mg 1996 - 1997 tapered off no problem - Prozac sporadic use between 1995 and 2011 usually 9 months then off.

Mirtazapine 2015 tapered off after 4 months no problem -Prozac 20mg 2012-2015 tapered off no problems

Prozac 20mg April 2016-May 2016 stopped ct after 4 weeks due to adverse reaction I believe to be serotnin toxicity due to mirtazapine interaction

Escitlopram 10 mg May 2016 - cut to 5mg May 2016  stopped ct November 2016 no W/d's noted

Lyrica 300mg May 2016 - July 2017 - Taper from Jan to Jul 17 awful taper.

Lofepramine 150mg  November 2016 - January 2017 Swift w/d as it didn't work

Quetiapine 75mg November 2016 changed to 150 XL May2017 changed to 150mg IR July 2017 reduced to in 25mg steps from July to 50mg Oct 17. 37.5mg 12th Nov 17 - 35mg 20 Nov 17 - 30mg 22 Nov 17 - 25mg 24 Nov 17 dropped to 20mg Dec 17, 15mg Jan 18. Current taken at bedtime.

Quetiapine dropped Jan 17th 2018.

Dosulepin 75mg May 2017 - increased in 25mg steps to 175mg Oct 17 Reduced to 150mg Nov 17 current taken at bedtime

Diazepam 15mg May 2016 - c/t'd by shrink after 6 weeks. Reinstated at 12mg after 4 weeks June 16 - current 4mg 3 times a day morning, 2.30pm and bedtime.

Mirtazapine 15mg since March 2015 - current - pooped out within 4 weeks

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  • Moderator Emeritus
On 09/09/2017 at 6:16 AM, Staz said:

I've made the decision to get off of as many meds as I can

 

And the title of your topic is:  trying to get drug free.

 

Your last post mentions options of more/different drugs by your shrink.

 

Surviving Antidepressants is a peer support site providing information and support for coming off drugs safely.

 

5 hours ago, Staz said:

My depression wasn't this bad before the meds.

 

These drugs can cause the issues which we are told they fix.  The book Your Drug May Be Your Problem by Dr Peter Breggin has a chapter talking about this.

 

There is also a thing called medication spell binding.  Dr Breggin talks about this in one of these Simple Truths About Psychiatry - Series of 10 by Dr Peter Breggin

 

My personal opinion is that what you are experiencing is being caused by the drugs you are taking.  I don't think taking a different drug or adding an additional drug to "fix" what is being caused by the original drugs is the answer.   Personally I think it would be better for you to be reducing your drugs by tapering.

 

I have been taking an antidepressant for 25 years.  It wasn't until my dose got lower that I started feeling my emotions again.  It wasn't until this happened that I realised that I had been numb for all those years.  I also experienced times of depression during that time and from what I have learned since being a member here, I would not be at all surprised if it was caused by the AD.  Now I'm not saying that I would not have experienced some depression if I hadn't been on an AD.  I do think that being numbed by the AD made it harder to use non drug coping techniques.  I would just give in to the depression because I didn't have any mental energy, whereas now I feel more alert and am better able to use techniques to get me through the times when my mood is more depressed.

Please DO NOT TAG me - thank you

PLEASE NOTE:  I am not a medical professional.  I provide information and make suggestions. 

  MISSION ACCOMPLISHED:    (6 year taper)      0mg Pristiq      on 13th November 2021

ADs since ~1992:  25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq:  50mg 2012, 100mg beg 2013 (Serotonin Toxicity)  Tapering from Oct 2015 - 13 Nov 2021   LAST DOSE 0.0025mg

Post 0 updates start here    My tapering program     My Intro (goes to tapering graph)

 VIDEO:   Antidepressant Withdrawal Syndrome and its Management

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32 minutes ago, ChessieCat said:

 

And the title of your topic is:  trying to get drug free.

 

Your last post mentions options of more/different drugs by your shrink.

 

Surviving Antidepressants is a peer support site providing information and support for coming off drugs safely.

 

 

These drugs can cause the issues which we are told they fix.  The book Your Drug May Be Your Problem by Dr Peter Breggin has a chapter talking about this.

 

There is also a thing called medication spell binding.  Dr Breggin talks about this in one of these Simple Truths About Psychiatry - Series of 10 by Dr Peter Breggin

 

My personal opinion is that what you are experiencing is being caused by the drugs you are taking.  I don't think taking a different drug or adding an additional drug to "fix" what is being caused by the original drugs is the answer.   Personally I think it would be better for you to be reducing your drugs by tapering.

 

I have been taking an antidepressant for 25 years.  It wasn't until my dose got lower that I started feeling my emotions again.  It wasn't until this happened that I realised that I had been numb for all those years.  I also experienced times of depression during that time and from what I have learned since being a member here, I would not be at all surprised if it was caused by the AD.  Now I'm not saying that I would not have experienced some depression if I hadn't been on an AD.  I do think that being numbed by the AD made it harder to use non drug coping techniques.  I would just give in to the depression because I didn't have any mental energy, whereas now I feel more alert and am better able to use techniques to get me through the times when my mood is more depressed.

I appreciate your response Chessie and agree with your overall synopsis of my situation. When you are poly drugged and suicidely depressed  where do you go.?My shrink gave me options as per my post and I think the only way is off but from a position of strength. I've come off of lyrica, escitalopram, prozac and  lofepramine in the last 18 months so my question to you is which is causing the disabling depression of my current meds? Where do I start and with which drug? Can I hang on that long or is adding another drug to help me ease of the rest a valid strategy as my depression is now considered unipolar and treatment resistant. I have the option of staying in the life threatening pit of misery or just maybe add a mood stabiliser. The choice is mine. I can stay where I am and try and stabilise before cutting one of the meds or maybe get some relief from another drug which has worked for some. The root cause is as you suggest. The path to take to reach my goal is a little less clear. Thanks for your opinion on the subject. also Dr Breggin I admire but he has a reputation of being selective with his clients although I agree with a lot of his ideas on the subject. Dr Healy here in the UK has also written extensively on the subject.

 

Staz.

 

Dosulepin 75mg 1996 - 1997 tapered off no problem - Prozac sporadic use between 1995 and 2011 usually 9 months then off.

Mirtazapine 2015 tapered off after 4 months no problem -Prozac 20mg 2012-2015 tapered off no problems

Prozac 20mg April 2016-May 2016 stopped ct after 4 weeks due to adverse reaction I believe to be serotnin toxicity due to mirtazapine interaction

Escitlopram 10 mg May 2016 - cut to 5mg May 2016  stopped ct November 2016 no W/d's noted

Lyrica 300mg May 2016 - July 2017 - Taper from Jan to Jul 17 awful taper.

Lofepramine 150mg  November 2016 - January 2017 Swift w/d as it didn't work

Quetiapine 75mg November 2016 changed to 150 XL May2017 changed to 150mg IR July 2017 reduced to in 25mg steps from July to 50mg Oct 17. 37.5mg 12th Nov 17 - 35mg 20 Nov 17 - 30mg 22 Nov 17 - 25mg 24 Nov 17 dropped to 20mg Dec 17, 15mg Jan 18. Current taken at bedtime.

Quetiapine dropped Jan 17th 2018.

Dosulepin 75mg May 2017 - increased in 25mg steps to 175mg Oct 17 Reduced to 150mg Nov 17 current taken at bedtime

Diazepam 15mg May 2016 - c/t'd by shrink after 6 weeks. Reinstated at 12mg after 4 weeks June 16 - current 4mg 3 times a day morning, 2.30pm and bedtime.

Mirtazapine 15mg since March 2015 - current - pooped out within 4 weeks

Link to comment
  • Moderator Emeritus

Are these the drugs you are currently taking?  Mirtazapine, Quetiapine, Dosulepin and Diazepam

 

If you are still taking Mirtazapine, please move it to the bottom of your signature so all of the current drugs are together.  Thank you.  Account Settings – Create or Edit a signature

 

Taking multiple psych drugs? Which drug to taper first?
"If you're not having an adverse reaction from the other medications, taper the most activating drug first. This is usually an antidepressant or stimulant (ADHD drug)."

 

That was a really big jump in dose of Dosulepin.  It is not available in the USA so it doesn't show up in the interaction checker we use.  However I've found another one here which does:  https://reference.medscape.com/drug-interactionchecker

 

It is usually best for the member to do their own check, but this one was a bit tricky to use so here are the results:

  • dosulepin + mirtazapine

    dosulepin and mirtazapine both increase serotonin levels. Modify Therapy/Monitor Closely.

  • diazepam + quetiapine

    diazepam and quetiapine both increase sedation. Use Caution/Monitor.

  • diazepam + dosulepin

    diazepam and dosulepin both increase sedation. Use Caution/Monitor.

  • diazepam + mirtazapine

    diazepam and mirtazapine both increase sedation. Use Caution/Monitor.

  • quetiapine + dosulepin

    quetiapine and dosulepin both increase sedation. Use Caution/Monitor.

  • quetiapine + mirtazapine

    quetiapine and mirtazapine both increase sedation. Use Caution/Monitor.

  • dosulepin + mirtazapine

    dosulepin and mirtazapine both increase sedation. Use Caution/Monitor.

 

I suggest you do a search on serotonin syndrome to see if you are experiencing this.  I had mild serotonin toxicity on 100mg Pristiq.  I was sweating a lot and had a feeling of being unsettled which could escalate into agitation/anxiety.  The sweating was an obvious issue but It wasn't until I reduced my dose that I realised how unsettled I had been.

 

Just thinking out loud here.  The sedating drugs may be covering up serotonin toxicity.  You might want to consider reducing the dose of dosulepin because that is the one which was increased by a large amount most recently and may be causing serotonin toxicity without you being aware of it.  Because you have only recently increased the dose you might be able to reduce faster than 10% x 4 week hold.  You could try 10% and see how you are after 3 weeks and maybe reduce again.  Or you could reduce by more than 10% but I wouldn't do anything more than 25%.  After getting your dose a bit lower on the dosulepin you could then start reducing one of the sedating drugs.

 

As I said, these are my thoughts.  I hope I've offered things for you to consider which can help you reduce your drug load.  The decision about how you do it is yours.

Please DO NOT TAG me - thank you

PLEASE NOTE:  I am not a medical professional.  I provide information and make suggestions. 

  MISSION ACCOMPLISHED:    (6 year taper)      0mg Pristiq      on 13th November 2021

ADs since ~1992:  25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq:  50mg 2012, 100mg beg 2013 (Serotonin Toxicity)  Tapering from Oct 2015 - 13 Nov 2021   LAST DOSE 0.0025mg

Post 0 updates start here    My tapering program     My Intro (goes to tapering graph)

 VIDEO:   Antidepressant Withdrawal Syndrome and its Management

Link to comment

Hi Chessie and thanks. That's some really useful information my friend. My Dosulepin was tapered up over a few weeks and I could probably reduce it quicker as a result. I hadn't considered seratonin toxicity but it would explain why I reacted so badly to Prozac which always worked for me when I was already on mirtazapine as I went straight to 20mg of prozac while on 15mg of mirt.  Going on and off prozac by itself hadn't ever caused me a problem in the past although that was years ago now. I'll cut my Dosulepin as you suggest as I think you might be onto something with your analysis of my meds. Thanks again and I'll amend my signature to reflect this and your request.

Staz

Dosulepin 75mg 1996 - 1997 tapered off no problem - Prozac sporadic use between 1995 and 2011 usually 9 months then off.

Mirtazapine 2015 tapered off after 4 months no problem -Prozac 20mg 2012-2015 tapered off no problems

Prozac 20mg April 2016-May 2016 stopped ct after 4 weeks due to adverse reaction I believe to be serotnin toxicity due to mirtazapine interaction

Escitlopram 10 mg May 2016 - cut to 5mg May 2016  stopped ct November 2016 no W/d's noted

Lyrica 300mg May 2016 - July 2017 - Taper from Jan to Jul 17 awful taper.

Lofepramine 150mg  November 2016 - January 2017 Swift w/d as it didn't work

Quetiapine 75mg November 2016 changed to 150 XL May2017 changed to 150mg IR July 2017 reduced to in 25mg steps from July to 50mg Oct 17. 37.5mg 12th Nov 17 - 35mg 20 Nov 17 - 30mg 22 Nov 17 - 25mg 24 Nov 17 dropped to 20mg Dec 17, 15mg Jan 18. Current taken at bedtime.

Quetiapine dropped Jan 17th 2018.

Dosulepin 75mg May 2017 - increased in 25mg steps to 175mg Oct 17 Reduced to 150mg Nov 17 current taken at bedtime

Diazepam 15mg May 2016 - c/t'd by shrink after 6 weeks. Reinstated at 12mg after 4 weeks June 16 - current 4mg 3 times a day morning, 2.30pm and bedtime.

Mirtazapine 15mg since March 2015 - current - pooped out within 4 weeks

Link to comment

You've really got me thinking now as the symptoms you describe Chessie were precisely what happened to me when the prozac was added to the mirt. The answer was to force feed me benzos and not on shrink or doctor ever mentioned this as a possibility. I know I should be tapering quetiapine first due to it's risks but knocking the dosulepin back may help me more in the short term.

Your research also explains why I'm so demotivated, tired and but anxious at the same time. I wish I'd posted earlier now.

Staz

19 hours ago, ChessieCat said:

Are these the drugs you are currently taking?  Mirtazapine, Quetiapine, Dosulepin and Diazepam

 

If you are still taking Mirtazapine, please move it to the bottom of your signature so all of the current drugs are together.  Thank you.  Account Settings – Create or Edit a signature

 

Taking multiple psych drugs? Which drug to taper first?
"If you're not having an adverse reaction from the other medications, taper the most activating drug first. This is usually an antidepressant or stimulant (ADHD drug)."

 

That was a really big jump in dose of Dosulepin.  It is not available in the USA so it doesn't show up in the interaction checker we use.  However I've found another one here which does:  https://reference.medscape.com/drug-interactionchecker

 

It is usually best for the member to do their own check, but this one was a bit tricky to use so here are the results:

  • dosulepin + mirtazapine

    dosulepin and mirtazapine both increase serotonin levels. Modify Therapy/Monitor Closely.

  • diazepam + quetiapine

    diazepam and quetiapine both increase sedation. Use Caution/Monitor.

  • diazepam + dosulepin

    diazepam and dosulepin both increase sedation. Use Caution/Monitor.

  • diazepam + mirtazapine

    diazepam and mirtazapine both increase sedation. Use Caution/Monitor.

  • quetiapine + dosulepin

    quetiapine and dosulepin both increase sedation. Use Caution/Monitor.

  • quetiapine + mirtazapine

    quetiapine and mirtazapine both increase sedation. Use Caution/Monitor.

  • dosulepin + mirtazapine

    dosulepin and mirtazapine both increase sedation. Use Caution/Monitor.

 

I suggest you do a search on serotonin syndrome to see if you are experiencing this.  I had mild serotonin toxicity on 100mg Pristiq.  I was sweating a lot and had a feeling of being unsettled which could escalate into agitation/anxiety.  The sweating was an obvious issue but It wasn't until I reduced my dose that I realised how unsettled I had been.

 

Just thinking out loud here.  The sedating drugs may be covering up serotonin toxicity.  You might want to consider reducing the dose of dosulepin because that is the one which was increased by a large amount most recently and may be causing serotonin toxicity without you being aware of it.  Because you have only recently increased the dose you might be able to reduce faster than 10% x 4 week hold.  You could try 10% and see how you are after 3 weeks and maybe reduce again.  Or you could reduce by more than 10% but I wouldn't do anything more than 25%.  After getting your dose a bit lower on the dosulepin you could then start reducing one of the sedating drugs.

 

As I said, these are my thoughts.  I hope I've offered things for you to consider which can help you reduce your drug load.  The decision about how you do it is yours.

 

Dosulepin 75mg 1996 - 1997 tapered off no problem - Prozac sporadic use between 1995 and 2011 usually 9 months then off.

Mirtazapine 2015 tapered off after 4 months no problem -Prozac 20mg 2012-2015 tapered off no problems

Prozac 20mg April 2016-May 2016 stopped ct after 4 weeks due to adverse reaction I believe to be serotnin toxicity due to mirtazapine interaction

Escitlopram 10 mg May 2016 - cut to 5mg May 2016  stopped ct November 2016 no W/d's noted

Lyrica 300mg May 2016 - July 2017 - Taper from Jan to Jul 17 awful taper.

Lofepramine 150mg  November 2016 - January 2017 Swift w/d as it didn't work

Quetiapine 75mg November 2016 changed to 150 XL May2017 changed to 150mg IR July 2017 reduced to in 25mg steps from July to 50mg Oct 17. 37.5mg 12th Nov 17 - 35mg 20 Nov 17 - 30mg 22 Nov 17 - 25mg 24 Nov 17 dropped to 20mg Dec 17, 15mg Jan 18. Current taken at bedtime.

Quetiapine dropped Jan 17th 2018.

Dosulepin 75mg May 2017 - increased in 25mg steps to 175mg Oct 17 Reduced to 150mg Nov 17 current taken at bedtime

Diazepam 15mg May 2016 - c/t'd by shrink after 6 weeks. Reinstated at 12mg after 4 weeks June 16 - current 4mg 3 times a day morning, 2.30pm and bedtime.

Mirtazapine 15mg since March 2015 - current - pooped out within 4 weeks

Link to comment

After reading the Quetipine/ Seroquel advice I think that will be the next taper. My shrink wants me off it at the rate of 25mg every 2 weeks which was ok until I hit 50mg. I've held at this dose for a month now. When would it be sensible to re start a 10% taper as I don't feel holding has really changed anything for me? The depression is still there but I'm sleeping 6 hours or so a night now. any advice from those who have tapered this drug would be appreciated.

Cheers

Staz

Dosulepin 75mg 1996 - 1997 tapered off no problem - Prozac sporadic use between 1995 and 2011 usually 9 months then off.

Mirtazapine 2015 tapered off after 4 months no problem -Prozac 20mg 2012-2015 tapered off no problems

Prozac 20mg April 2016-May 2016 stopped ct after 4 weeks due to adverse reaction I believe to be serotnin toxicity due to mirtazapine interaction

Escitlopram 10 mg May 2016 - cut to 5mg May 2016  stopped ct November 2016 no W/d's noted

Lyrica 300mg May 2016 - July 2017 - Taper from Jan to Jul 17 awful taper.

Lofepramine 150mg  November 2016 - January 2017 Swift w/d as it didn't work

Quetiapine 75mg November 2016 changed to 150 XL May2017 changed to 150mg IR July 2017 reduced to in 25mg steps from July to 50mg Oct 17. 37.5mg 12th Nov 17 - 35mg 20 Nov 17 - 30mg 22 Nov 17 - 25mg 24 Nov 17 dropped to 20mg Dec 17, 15mg Jan 18. Current taken at bedtime.

Quetiapine dropped Jan 17th 2018.

Dosulepin 75mg May 2017 - increased in 25mg steps to 175mg Oct 17 Reduced to 150mg Nov 17 current taken at bedtime

Diazepam 15mg May 2016 - c/t'd by shrink after 6 weeks. Reinstated at 12mg after 4 weeks June 16 - current 4mg 3 times a day morning, 2.30pm and bedtime.

Mirtazapine 15mg since March 2015 - current - pooped out within 4 weeks

Link to comment

I'm just about to re start my taper down on seroquel from 50mg which I've been on for 4 weeks or so. I'm not sure which method to go for as I have scales and also accurate lab standard measuring jars and syringes. Dry cutting seems to be too much of a pain and I got off Lyrica using the water titration method although that is water soluble.

Dosulepin 75mg 1996 - 1997 tapered off no problem - Prozac sporadic use between 1995 and 2011 usually 9 months then off.

Mirtazapine 2015 tapered off after 4 months no problem -Prozac 20mg 2012-2015 tapered off no problems

Prozac 20mg April 2016-May 2016 stopped ct after 4 weeks due to adverse reaction I believe to be serotnin toxicity due to mirtazapine interaction

Escitlopram 10 mg May 2016 - cut to 5mg May 2016  stopped ct November 2016 no W/d's noted

Lyrica 300mg May 2016 - July 2017 - Taper from Jan to Jul 17 awful taper.

Lofepramine 150mg  November 2016 - January 2017 Swift w/d as it didn't work

Quetiapine 75mg November 2016 changed to 150 XL May2017 changed to 150mg IR July 2017 reduced to in 25mg steps from July to 50mg Oct 17. 37.5mg 12th Nov 17 - 35mg 20 Nov 17 - 30mg 22 Nov 17 - 25mg 24 Nov 17 dropped to 20mg Dec 17, 15mg Jan 18. Current taken at bedtime.

Quetiapine dropped Jan 17th 2018.

Dosulepin 75mg May 2017 - increased in 25mg steps to 175mg Oct 17 Reduced to 150mg Nov 17 current taken at bedtime

Diazepam 15mg May 2016 - c/t'd by shrink after 6 weeks. Reinstated at 12mg after 4 weeks June 16 - current 4mg 3 times a day morning, 2.30pm and bedtime.

Mirtazapine 15mg since March 2015 - current - pooped out within 4 weeks

Link to comment

Ok. I've gone for it and dropped from 50mg of Quetiapine /seroquel to 37.5mg last night. I'm going to hold at this dose until Christmas. In the New Year I'll be doing 10% cuts from 37.5mg.

Dosulepin 75mg 1996 - 1997 tapered off no problem - Prozac sporadic use between 1995 and 2011 usually 9 months then off.

Mirtazapine 2015 tapered off after 4 months no problem -Prozac 20mg 2012-2015 tapered off no problems

Prozac 20mg April 2016-May 2016 stopped ct after 4 weeks due to adverse reaction I believe to be serotnin toxicity due to mirtazapine interaction

Escitlopram 10 mg May 2016 - cut to 5mg May 2016  stopped ct November 2016 no W/d's noted

Lyrica 300mg May 2016 - July 2017 - Taper from Jan to Jul 17 awful taper.

Lofepramine 150mg  November 2016 - January 2017 Swift w/d as it didn't work

Quetiapine 75mg November 2016 changed to 150 XL May2017 changed to 150mg IR July 2017 reduced to in 25mg steps from July to 50mg Oct 17. 37.5mg 12th Nov 17 - 35mg 20 Nov 17 - 30mg 22 Nov 17 - 25mg 24 Nov 17 dropped to 20mg Dec 17, 15mg Jan 18. Current taken at bedtime.

Quetiapine dropped Jan 17th 2018.

Dosulepin 75mg May 2017 - increased in 25mg steps to 175mg Oct 17 Reduced to 150mg Nov 17 current taken at bedtime

Diazepam 15mg May 2016 - c/t'd by shrink after 6 weeks. Reinstated at 12mg after 4 weeks June 16 - current 4mg 3 times a day morning, 2.30pm and bedtime.

Mirtazapine 15mg since March 2015 - current - pooped out within 4 weeks

Link to comment

After reading up  on Tardive dyskinesia I've decided to accelerate my reduction of Seroquel/Quetiapine. I'd not realised the potential harm this class of drugs can do even at low doses. I'm showing no signs of TD and have dropped to 30mg at night but even low dose carries a risk that I'm not prepared to accept. I've read that after 5 years usage roughly 20% of patients treated with antipsychotics develop TD.

Dosulepin 75mg 1996 - 1997 tapered off no problem - Prozac sporadic use between 1995 and 2011 usually 9 months then off.

Mirtazapine 2015 tapered off after 4 months no problem -Prozac 20mg 2012-2015 tapered off no problems

Prozac 20mg April 2016-May 2016 stopped ct after 4 weeks due to adverse reaction I believe to be serotnin toxicity due to mirtazapine interaction

Escitlopram 10 mg May 2016 - cut to 5mg May 2016  stopped ct November 2016 no W/d's noted

Lyrica 300mg May 2016 - July 2017 - Taper from Jan to Jul 17 awful taper.

Lofepramine 150mg  November 2016 - January 2017 Swift w/d as it didn't work

Quetiapine 75mg November 2016 changed to 150 XL May2017 changed to 150mg IR July 2017 reduced to in 25mg steps from July to 50mg Oct 17. 37.5mg 12th Nov 17 - 35mg 20 Nov 17 - 30mg 22 Nov 17 - 25mg 24 Nov 17 dropped to 20mg Dec 17, 15mg Jan 18. Current taken at bedtime.

Quetiapine dropped Jan 17th 2018.

Dosulepin 75mg May 2017 - increased in 25mg steps to 175mg Oct 17 Reduced to 150mg Nov 17 current taken at bedtime

Diazepam 15mg May 2016 - c/t'd by shrink after 6 weeks. Reinstated at 12mg after 4 weeks June 16 - current 4mg 3 times a day morning, 2.30pm and bedtime.

Mirtazapine 15mg since March 2015 - current - pooped out within 4 weeks

Link to comment
  • 2 weeks later...

I dropped Seroquel to 25mg on the 24th Nov and haven't felt well at all since. I know I've cut to quickly and i'm considering going back to 50mg. Accelerating wasn't a good idea. 

Shep has also pointed out to me the sheer volume of changes in my meds during the last year could have destabilised me so I'm going to stay with my current meds through until Feb I think and try and get my cns settled a bit. I'm still uncertain about upping the seroquel again so any comments or opinions would be appreciated.

Staz

 

Dosulepin 75mg 1996 - 1997 tapered off no problem - Prozac sporadic use between 1995 and 2011 usually 9 months then off.

Mirtazapine 2015 tapered off after 4 months no problem -Prozac 20mg 2012-2015 tapered off no problems

Prozac 20mg April 2016-May 2016 stopped ct after 4 weeks due to adverse reaction I believe to be serotnin toxicity due to mirtazapine interaction

Escitlopram 10 mg May 2016 - cut to 5mg May 2016  stopped ct November 2016 no W/d's noted

Lyrica 300mg May 2016 - July 2017 - Taper from Jan to Jul 17 awful taper.

Lofepramine 150mg  November 2016 - January 2017 Swift w/d as it didn't work

Quetiapine 75mg November 2016 changed to 150 XL May2017 changed to 150mg IR July 2017 reduced to in 25mg steps from July to 50mg Oct 17. 37.5mg 12th Nov 17 - 35mg 20 Nov 17 - 30mg 22 Nov 17 - 25mg 24 Nov 17 dropped to 20mg Dec 17, 15mg Jan 18. Current taken at bedtime.

Quetiapine dropped Jan 17th 2018.

Dosulepin 75mg May 2017 - increased in 25mg steps to 175mg Oct 17 Reduced to 150mg Nov 17 current taken at bedtime

Diazepam 15mg May 2016 - c/t'd by shrink after 6 weeks. Reinstated at 12mg after 4 weeks June 16 - current 4mg 3 times a day morning, 2.30pm and bedtime.

Mirtazapine 15mg since March 2015 - current - pooped out within 4 weeks

Link to comment

Yes, you might need to updose and hold for awhile, surely a mod will come along who can give you suggestions. It sounds like you've tapered your dose too fast and your CNS is already destabilized.

 

A few months ago I was tapering only by 6% of my last dose, but I was tapering a little too fast - the mods warned me about going too fast and they were right, I started getting WD's and I learned my lesson. Tapering from these drugs is no joke. I hope you start feeling better soon.

Apr 09 2013 started taking 30mg Remeron

Oct 10 2013 began tapering 27 mg  Nov 07/ 24 mg  Nov 27/ 22 mg  Dec 20/ 20mg

***Stopped taper and reinstated back up to 30mg shortly afterwards due to the symptoms that I was taking Remeron for came back. The Exact Same symptoms. I wasn't willing to live through that again.

2nd attempt at tapering.

Feb 20 2017/ 28 mg  Mar 20/ 25 mg   Apr 20/ 23 mg  May 21/ 22mg  June 21/ 21mg  July 15/ 20mg  Aug 5/ 19mg Aug22/18mg  Oct 21/ 17 mg  Nov 27/ 16 mg  Dec 26/ 15mg  Jan 27 2018/ 14mg  Mar 1/ 13mg  Mar 31/ 12 mg 

Apr 28/ 11mg  May 27/ 10 mg  July 7/ 9 mg  Aug 4/ 8.1 mg  Aug 31/ 7.2 mg  Sept 29/ 6.3 mg  Oct 28/ 5.6 mg 

Nov 26/ 5 mg  Dec 25/ 4.5 mg   01/03/2020 .65 mg  03/11/20  - 0.36 mg- omg omw to being AD free!

 

I also take 30mg Temazepam for sleep every night, Pulmicort 180mcg inhaler 2x/day for cough variant asthma, albuterol inhaler as needed, Vitamin D, Vitamin C, omega 3 fish oil, 400mg magnesium malate, potassium iodide, CBD oil 25 - 30mgs/day

 

HOPE = Hold On, Pain Ends

Link to comment

Thank you Kitson,

My depression is getting out of control now and I'm worried for my own safety tbh.

Dosulepin 75mg 1996 - 1997 tapered off no problem - Prozac sporadic use between 1995 and 2011 usually 9 months then off.

Mirtazapine 2015 tapered off after 4 months no problem -Prozac 20mg 2012-2015 tapered off no problems

Prozac 20mg April 2016-May 2016 stopped ct after 4 weeks due to adverse reaction I believe to be serotnin toxicity due to mirtazapine interaction

Escitlopram 10 mg May 2016 - cut to 5mg May 2016  stopped ct November 2016 no W/d's noted

Lyrica 300mg May 2016 - July 2017 - Taper from Jan to Jul 17 awful taper.

Lofepramine 150mg  November 2016 - January 2017 Swift w/d as it didn't work

Quetiapine 75mg November 2016 changed to 150 XL May2017 changed to 150mg IR July 2017 reduced to in 25mg steps from July to 50mg Oct 17. 37.5mg 12th Nov 17 - 35mg 20 Nov 17 - 30mg 22 Nov 17 - 25mg 24 Nov 17 dropped to 20mg Dec 17, 15mg Jan 18. Current taken at bedtime.

Quetiapine dropped Jan 17th 2018.

Dosulepin 75mg May 2017 - increased in 25mg steps to 175mg Oct 17 Reduced to 150mg Nov 17 current taken at bedtime

Diazepam 15mg May 2016 - c/t'd by shrink after 6 weeks. Reinstated at 12mg after 4 weeks June 16 - current 4mg 3 times a day morning, 2.30pm and bedtime.

Mirtazapine 15mg since March 2015 - current - pooped out within 4 weeks

Link to comment

I think I've kindled due to my benzo reinstatement. It feels like I've wasted 18 months. I'm in such poor mental state I don't know how I'm ever going to get off of Valium no. It feels like constant withdrawal.

 

Dosulepin 75mg 1996 - 1997 tapered off no problem - Prozac sporadic use between 1995 and 2011 usually 9 months then off.

Mirtazapine 2015 tapered off after 4 months no problem -Prozac 20mg 2012-2015 tapered off no problems

Prozac 20mg April 2016-May 2016 stopped ct after 4 weeks due to adverse reaction I believe to be serotnin toxicity due to mirtazapine interaction

Escitlopram 10 mg May 2016 - cut to 5mg May 2016  stopped ct November 2016 no W/d's noted

Lyrica 300mg May 2016 - July 2017 - Taper from Jan to Jul 17 awful taper.

Lofepramine 150mg  November 2016 - January 2017 Swift w/d as it didn't work

Quetiapine 75mg November 2016 changed to 150 XL May2017 changed to 150mg IR July 2017 reduced to in 25mg steps from July to 50mg Oct 17. 37.5mg 12th Nov 17 - 35mg 20 Nov 17 - 30mg 22 Nov 17 - 25mg 24 Nov 17 dropped to 20mg Dec 17, 15mg Jan 18. Current taken at bedtime.

Quetiapine dropped Jan 17th 2018.

Dosulepin 75mg May 2017 - increased in 25mg steps to 175mg Oct 17 Reduced to 150mg Nov 17 current taken at bedtime

Diazepam 15mg May 2016 - c/t'd by shrink after 6 weeks. Reinstated at 12mg after 4 weeks June 16 - current 4mg 3 times a day morning, 2.30pm and bedtime.

Mirtazapine 15mg since March 2015 - current - pooped out within 4 weeks

Link to comment

Update - Still not settled from my quick drop of Quetiapine. Suffering increased depression and crying jags daily but still holding on just. i really don't want to up dose this med so will leave it to settle for another week before any decision on up dosing is made.

 

I've been surprised by my reaction as at this dose I thought it just acted like a giant antihistamine.

Staz

Dosulepin 75mg 1996 - 1997 tapered off no problem - Prozac sporadic use between 1995 and 2011 usually 9 months then off.

Mirtazapine 2015 tapered off after 4 months no problem -Prozac 20mg 2012-2015 tapered off no problems

Prozac 20mg April 2016-May 2016 stopped ct after 4 weeks due to adverse reaction I believe to be serotnin toxicity due to mirtazapine interaction

Escitlopram 10 mg May 2016 - cut to 5mg May 2016  stopped ct November 2016 no W/d's noted

Lyrica 300mg May 2016 - July 2017 - Taper from Jan to Jul 17 awful taper.

Lofepramine 150mg  November 2016 - January 2017 Swift w/d as it didn't work

Quetiapine 75mg November 2016 changed to 150 XL May2017 changed to 150mg IR July 2017 reduced to in 25mg steps from July to 50mg Oct 17. 37.5mg 12th Nov 17 - 35mg 20 Nov 17 - 30mg 22 Nov 17 - 25mg 24 Nov 17 dropped to 20mg Dec 17, 15mg Jan 18. Current taken at bedtime.

Quetiapine dropped Jan 17th 2018.

Dosulepin 75mg May 2017 - increased in 25mg steps to 175mg Oct 17 Reduced to 150mg Nov 17 current taken at bedtime

Diazepam 15mg May 2016 - c/t'd by shrink after 6 weeks. Reinstated at 12mg after 4 weeks June 16 - current 4mg 3 times a day morning, 2.30pm and bedtime.

Mirtazapine 15mg since March 2015 - current - pooped out within 4 weeks

Link to comment

Hi Staz, I only became a member yesterday and stumbled across your posts today.  We share a similar situation in regards to polypharmacy.  I am so sorry you are going through such turmoil.  Your descriptions are very familiar to me.  I also experienced terrible withdrawal from Quetiapin XR, however, it is difficult to seperate w/d, side effects and drug interactions when multiple medications of different classes are involved.  After multiple drug withdraws (unfortunately before I found this site) I still have three to go. Clonazepam, dexamphetamine and fluoxetine. 

K

  • Citalopram 20mg - 40mg ~ approx 2010 - October 2015 (stopped over one week)
  • Parnate  20mg - 50mg and olazapine 5mg ~ Jan 2016 - May 2016 (ceased over 2 days) 
  • Lithium 450mg-900 mg and Thyroxin ~May 2016 - May 2017
  • Diazepam various doses (including PRN) ~ 2015 - 2017
  • Oxazepam various doses (including PRN) ~ May 2016 - June 2016
  • Lurasidone 20mg ~Mid May 2016 - Mid June 2016
  • Vortioxetine 10mg - 20mg ~ 6th June 2016 - 20th July 2016 (abruptly ceased)
  • Amitriptyline 200mg ~July 2016 - September 2016 (ceased over 1 week)
  • Nortriptyline  (dose ?) ~October 2016 ~ November 2016 (abruptly ceased)
  • Seroquel XR 100mg - 300mg ~ May 2016 - August 2017 (ceased over 3 weeks)
  • Escitalopram 10mg - 30mg ~ August 2016 - March 2017 (ceased over 2 weeks)
  • Bupropion 300mg ~ December 2016 - May 2017 (ceased over 1 week)
  • Clonazepam 1.5mg daily ~ July 2016 (started tapering May 2017 - September 2017 currently on 0.375mg..ie 0.125mg TDS) 27th May 2018 5% 0.357mg (possible paradoxical reaction - see benzo thread)  28th June 5% 0.337mg, 28th July 10% 0.303mg, 12th September10% 0.272mg, 18th September reinstated 10% due to intolerable WD 0.303mg, 1st October-11th Oct 10% (1% reduction over 10 days) 0.272mg, 22nd October clonazepam ceased crossed over 10mg diazepam
  •  Dexamphatamine 20mg ~ December 2016 (started tapering October 2017 - tapered 1.25mg 4th Dec 2017, 1.25mg 19th Dec 2017 6.25mg, Speed up decrease due to major interaction between Dex and fluoxetine- ref to thread 10% 17th Feb 2018 5.63mg, 10% 21st Feb 2018 5.1mg, 10% 26th Feb 2018 4.5mg 10% 28th Feb 4.1mg, 10% 1st March 3.7mg, 10% 5th March 3.3mg, 10% 8th March 3mg, 10% 10th March 2.7mg, 10% 12th March 2.4mg, 10% 14th March 2.16mg, 10% 16th March 1.94mg, 10% 18th March 1.74mg, 10% 20th March 1.57mg, 10% 21st March 1.41mg, 10% 22nd March 1.26mg, 10% 23rd March 1.13mg, 10% 24th March 1.01mg, 10% 25th March 0.9mg, 10% 27th March 0.81mg, 10% 29th March 0.73mg, 10% 31st March 0.66mg, 10% 2nd April 0.59mg , 10% 4th April 0.53mg, 10% 6th April 0.47mg, 10% 8th April 0.42mg, 10%10th April 0.37mg, 11th April 0.2mg, 12th April 0.1mg (last dose) OFF! 
  • Fluoxetine 40mg ~December 2016 - 31 Jan 2018 reduced to 20mg (probable serotonin toxicity) 10th March 2020 10mg, 7th April 9mg, 1st May 8.5mg, 15th May 8.0mg, 27th May 7.5mg, 8th Sept 7.2mg, 2nd Oct 7mg, 19th Oct 6.8mg, 28th Oct 6.6mg, 5th Nov 6.4mg, 26th Nov 6mg, 2nd April 2021 5.9mg, 9th April 5.8mg, 19th April 5.75mg, 22nd April 5.7mg, 26th April 5.65mg,28th April 5.6mg, 1st May 5.5mg, 4th May 5.45mg, 7th May 5.4mg, 10th May 5.35mg, 12th May 5.3mg, 15th May 5.25mg, 18th May 5.2mg, 20th May 5.15mg, 22nd May 5mg, 10th July 4.5mg, 9th Aug 4.48mg (switched from syringe to pipette method), 12th Aug 4.46mg, 14th Aug 4.4mg, 18th Aug 4.38mg, 19th Aug 4.36mg, 20th Aug 4.34, 21st 4.32mg, 22nd 4.3mg, 23rd Aug 4mg (hold), (micro-taper) 12th Oct 2021 3.98mg, 14th Oct 3.96mg, 15th Oct 3.94mg, 16th Oct 3.92mg, 17th Oct 3.9mg, 18th Oct 3.88mg, 19th Oct 3.86mg, 21st Oct 3.84mg, 22nd Oct 3.82mg, 23rd Oct 3.8mg, 24th Oct 3.78mg, 25th Oct 3.76mg, 26th Oct 3.74mg, 27th Oct 3.72mg, (WD reached intolerable level, reinstated 0.06mg) 28th Oct 3.8mg, 7th March 2022 3.7mg, 21st March 3.6mg, 4th April 3.5mg, 18th April 3.4mg, 2nd May 3.3mg, 16th May 3.2mg, 20th June 3.1mg, 4th July 3mg, 18th July 2.9mg, 12th September 2.7mg, 18th October 2.5mg, 14th Nov 2.3mg
  • Diazepam 10mg ~ 22nd Oct 2018, 10th November 8mg, 14th Nov 7mg, 8th December 6mg, 30th December 5mg (Nocte), 7th March 2019 4.5mg,14th March 4mg, 5th April 3.5mg, 9th April 3mg, 18th April 2.5mg,1st May 2mg, 17th May 1.75mg, 25th May 1.6mg, 4th June 1.59mg, 5th June 1.58mg, 6th June 1.57mg, 7th June 1.56mg, 8th June 1.55mg, 22nd June 1.4mg, 4th July 1.2mg, 16th July 1mg, 30th July 0.8mg, 13th Aug 0.6mg, 28th Aug 0.4mg, 10th Sept 0.2mg, 23rd Sept Off! 
  • SR Circadin 2mg (melatonin) 25th May - 20th June 
  • Zolpidem 10mg 25th May (7 tablets)
  • Supplements: Magnesium glycinate (soluble - sip throughout the day) 

 

"Whenever you feel yourself doubting how far you can go,  just remember how far you have come.  Remember everything you have faced, all the battles you have won, and all the fears you have overcome"    Unknown 

Link to comment

Thanks for your reply Kristine. My depression is crushing me and my life is a living hell. I'm sorry you have been down the same path as me but you seem to be moving in the right direction. I'm loosing hope tbh as I've had no relief at all from drug or combination of drugs. How are you feeling?

Staz

Dosulepin 75mg 1996 - 1997 tapered off no problem - Prozac sporadic use between 1995 and 2011 usually 9 months then off.

Mirtazapine 2015 tapered off after 4 months no problem -Prozac 20mg 2012-2015 tapered off no problems

Prozac 20mg April 2016-May 2016 stopped ct after 4 weeks due to adverse reaction I believe to be serotnin toxicity due to mirtazapine interaction

Escitlopram 10 mg May 2016 - cut to 5mg May 2016  stopped ct November 2016 no W/d's noted

Lyrica 300mg May 2016 - July 2017 - Taper from Jan to Jul 17 awful taper.

Lofepramine 150mg  November 2016 - January 2017 Swift w/d as it didn't work

Quetiapine 75mg November 2016 changed to 150 XL May2017 changed to 150mg IR July 2017 reduced to in 25mg steps from July to 50mg Oct 17. 37.5mg 12th Nov 17 - 35mg 20 Nov 17 - 30mg 22 Nov 17 - 25mg 24 Nov 17 dropped to 20mg Dec 17, 15mg Jan 18. Current taken at bedtime.

Quetiapine dropped Jan 17th 2018.

Dosulepin 75mg May 2017 - increased in 25mg steps to 175mg Oct 17 Reduced to 150mg Nov 17 current taken at bedtime

Diazepam 15mg May 2016 - c/t'd by shrink after 6 weeks. Reinstated at 12mg after 4 weeks June 16 - current 4mg 3 times a day morning, 2.30pm and bedtime.

Mirtazapine 15mg since March 2015 - current - pooped out within 4 weeks

Link to comment

Hi Staz, I'm sorry you feel so terrible :( It can feel very isolating when these emotional and physical symptoms are relentless.  However, there is always hope.  My symptoms have improved a little over the past week but I have not tapered anymore medication during this time.  I know that I must be patient and not rush this process. Other medications have been ceased abruptly by a psychiatrists and unfortunately I think this will prolong my recovery time.  But that is in the past and even though I can't change these events I can certainly learn from them.  I have accepted that this will take years, but that's ok.  Over the past five years I have kept a journal recording various events in my life including medications, side effects ect.  I will be working on a post describing various symptoms and side effects from a variety of medication. Hopefully this will be helpful.  In my journal I have noted some of the experiences when I w/d from quetiapine however they could also be linked with clonazepam w/d

  • migraine (mostly right side of head) have to sit in dark room, light hurts eyes
  • nausea (chewing crystallised ginger or ginger tea helped) - vomited a few times
  • no appetite 
  • feeling dizzy and off balance (vertigo) 
  • very irritable - felt like screaming 
  • fatigue but unable to rest / brain won't stop buzzing
  • unable to regulate my body temperature. Shivering and sweating
  • Fluctuating moods, one minute I feel flat and emotionless the next I am sobbing and can't stop
  • Terrible insomnia (this lasted for two weeks)
  • muscular aches and pains
  • also during this period I fractured my ankle (due to balance issues) this didn't help!
  • my head/brain heavy and uncomfortable, often felt like a hornets nest
  • tremour in hands
  • unable to do simple tasks let alone multitask (I used to be the queen of multitasking!)

hopefully you you find some comfort in this. K

  • Citalopram 20mg - 40mg ~ approx 2010 - October 2015 (stopped over one week)
  • Parnate  20mg - 50mg and olazapine 5mg ~ Jan 2016 - May 2016 (ceased over 2 days) 
  • Lithium 450mg-900 mg and Thyroxin ~May 2016 - May 2017
  • Diazepam various doses (including PRN) ~ 2015 - 2017
  • Oxazepam various doses (including PRN) ~ May 2016 - June 2016
  • Lurasidone 20mg ~Mid May 2016 - Mid June 2016
  • Vortioxetine 10mg - 20mg ~ 6th June 2016 - 20th July 2016 (abruptly ceased)
  • Amitriptyline 200mg ~July 2016 - September 2016 (ceased over 1 week)
  • Nortriptyline  (dose ?) ~October 2016 ~ November 2016 (abruptly ceased)
  • Seroquel XR 100mg - 300mg ~ May 2016 - August 2017 (ceased over 3 weeks)
  • Escitalopram 10mg - 30mg ~ August 2016 - March 2017 (ceased over 2 weeks)
  • Bupropion 300mg ~ December 2016 - May 2017 (ceased over 1 week)
  • Clonazepam 1.5mg daily ~ July 2016 (started tapering May 2017 - September 2017 currently on 0.375mg..ie 0.125mg TDS) 27th May 2018 5% 0.357mg (possible paradoxical reaction - see benzo thread)  28th June 5% 0.337mg, 28th July 10% 0.303mg, 12th September10% 0.272mg, 18th September reinstated 10% due to intolerable WD 0.303mg, 1st October-11th Oct 10% (1% reduction over 10 days) 0.272mg, 22nd October clonazepam ceased crossed over 10mg diazepam
  •  Dexamphatamine 20mg ~ December 2016 (started tapering October 2017 - tapered 1.25mg 4th Dec 2017, 1.25mg 19th Dec 2017 6.25mg, Speed up decrease due to major interaction between Dex and fluoxetine- ref to thread 10% 17th Feb 2018 5.63mg, 10% 21st Feb 2018 5.1mg, 10% 26th Feb 2018 4.5mg 10% 28th Feb 4.1mg, 10% 1st March 3.7mg, 10% 5th March 3.3mg, 10% 8th March 3mg, 10% 10th March 2.7mg, 10% 12th March 2.4mg, 10% 14th March 2.16mg, 10% 16th March 1.94mg, 10% 18th March 1.74mg, 10% 20th March 1.57mg, 10% 21st March 1.41mg, 10% 22nd March 1.26mg, 10% 23rd March 1.13mg, 10% 24th March 1.01mg, 10% 25th March 0.9mg, 10% 27th March 0.81mg, 10% 29th March 0.73mg, 10% 31st March 0.66mg, 10% 2nd April 0.59mg , 10% 4th April 0.53mg, 10% 6th April 0.47mg, 10% 8th April 0.42mg, 10%10th April 0.37mg, 11th April 0.2mg, 12th April 0.1mg (last dose) OFF! 
  • Fluoxetine 40mg ~December 2016 - 31 Jan 2018 reduced to 20mg (probable serotonin toxicity) 10th March 2020 10mg, 7th April 9mg, 1st May 8.5mg, 15th May 8.0mg, 27th May 7.5mg, 8th Sept 7.2mg, 2nd Oct 7mg, 19th Oct 6.8mg, 28th Oct 6.6mg, 5th Nov 6.4mg, 26th Nov 6mg, 2nd April 2021 5.9mg, 9th April 5.8mg, 19th April 5.75mg, 22nd April 5.7mg, 26th April 5.65mg,28th April 5.6mg, 1st May 5.5mg, 4th May 5.45mg, 7th May 5.4mg, 10th May 5.35mg, 12th May 5.3mg, 15th May 5.25mg, 18th May 5.2mg, 20th May 5.15mg, 22nd May 5mg, 10th July 4.5mg, 9th Aug 4.48mg (switched from syringe to pipette method), 12th Aug 4.46mg, 14th Aug 4.4mg, 18th Aug 4.38mg, 19th Aug 4.36mg, 20th Aug 4.34, 21st 4.32mg, 22nd 4.3mg, 23rd Aug 4mg (hold), (micro-taper) 12th Oct 2021 3.98mg, 14th Oct 3.96mg, 15th Oct 3.94mg, 16th Oct 3.92mg, 17th Oct 3.9mg, 18th Oct 3.88mg, 19th Oct 3.86mg, 21st Oct 3.84mg, 22nd Oct 3.82mg, 23rd Oct 3.8mg, 24th Oct 3.78mg, 25th Oct 3.76mg, 26th Oct 3.74mg, 27th Oct 3.72mg, (WD reached intolerable level, reinstated 0.06mg) 28th Oct 3.8mg, 7th March 2022 3.7mg, 21st March 3.6mg, 4th April 3.5mg, 18th April 3.4mg, 2nd May 3.3mg, 16th May 3.2mg, 20th June 3.1mg, 4th July 3mg, 18th July 2.9mg, 12th September 2.7mg, 18th October 2.5mg, 14th Nov 2.3mg
  • Diazepam 10mg ~ 22nd Oct 2018, 10th November 8mg, 14th Nov 7mg, 8th December 6mg, 30th December 5mg (Nocte), 7th March 2019 4.5mg,14th March 4mg, 5th April 3.5mg, 9th April 3mg, 18th April 2.5mg,1st May 2mg, 17th May 1.75mg, 25th May 1.6mg, 4th June 1.59mg, 5th June 1.58mg, 6th June 1.57mg, 7th June 1.56mg, 8th June 1.55mg, 22nd June 1.4mg, 4th July 1.2mg, 16th July 1mg, 30th July 0.8mg, 13th Aug 0.6mg, 28th Aug 0.4mg, 10th Sept 0.2mg, 23rd Sept Off! 
  • SR Circadin 2mg (melatonin) 25th May - 20th June 
  • Zolpidem 10mg 25th May (7 tablets)
  • Supplements: Magnesium glycinate (soluble - sip throughout the day) 

 

"Whenever you feel yourself doubting how far you can go,  just remember how far you have come.  Remember everything you have faced, all the battles you have won, and all the fears you have overcome"    Unknown 

Link to comment

Thank you Kristine.

I'm sat alone in my house with no job and suffering daily a mental torture that only those that have been through it could understand. I've never been stable at all due to the meds and changes. My symptoms of reducing Seroquel have mainly been depression but I've also been drinking 2-3 beers a night for a long time now just to feel 'normal' I know I need to quit this as it's probably making things a lot worse than they need be and I don't want it to escalate which is always a danger. Self medicating doesn't work in the long run. My only hope is to stop drinking and wean off of my meds. I don't know if I've the strength left to do this though. I feel completely exhausted and haven't felt happiness or relaxation for so long now.

Staz

Dosulepin 75mg 1996 - 1997 tapered off no problem - Prozac sporadic use between 1995 and 2011 usually 9 months then off.

Mirtazapine 2015 tapered off after 4 months no problem -Prozac 20mg 2012-2015 tapered off no problems

Prozac 20mg April 2016-May 2016 stopped ct after 4 weeks due to adverse reaction I believe to be serotnin toxicity due to mirtazapine interaction

Escitlopram 10 mg May 2016 - cut to 5mg May 2016  stopped ct November 2016 no W/d's noted

Lyrica 300mg May 2016 - July 2017 - Taper from Jan to Jul 17 awful taper.

Lofepramine 150mg  November 2016 - January 2017 Swift w/d as it didn't work

Quetiapine 75mg November 2016 changed to 150 XL May2017 changed to 150mg IR July 2017 reduced to in 25mg steps from July to 50mg Oct 17. 37.5mg 12th Nov 17 - 35mg 20 Nov 17 - 30mg 22 Nov 17 - 25mg 24 Nov 17 dropped to 20mg Dec 17, 15mg Jan 18. Current taken at bedtime.

Quetiapine dropped Jan 17th 2018.

Dosulepin 75mg May 2017 - increased in 25mg steps to 175mg Oct 17 Reduced to 150mg Nov 17 current taken at bedtime

Diazepam 15mg May 2016 - c/t'd by shrink after 6 weeks. Reinstated at 12mg after 4 weeks June 16 - current 4mg 3 times a day morning, 2.30pm and bedtime.

Mirtazapine 15mg since March 2015 - current - pooped out within 4 weeks

Link to comment

Hi Staz , I can relate with a lot you say.i quit drink nearly 3 years ago ,I was a huge binge drinker .its the best thing I ever did .2 /3 beers to me doesn't seem too much ,but stopping anything that would make your recovery better is good .be careful because the depression makes us have guilt feelings .if you think stopping drink is a good thing ,maybe you could actively pursue it ,don't read the horror stories at this time ,we can be easily triggered .

You have hope as you've written ,this is a good sign .

Take care 

PB

Alcohol free since February 2015 

1MG diazepam

4.5MG PROZAC.

 

 

 

Link to comment

Thank you Powerback,

I'm going to stop drinking today and see if it helps my depression. It's supposed to deplete serotonin so is probably working against my meds now. Hopefully a few weeks dry I should see a bit of an improvement.

Dosulepin 75mg 1996 - 1997 tapered off no problem - Prozac sporadic use between 1995 and 2011 usually 9 months then off.

Mirtazapine 2015 tapered off after 4 months no problem -Prozac 20mg 2012-2015 tapered off no problems

Prozac 20mg April 2016-May 2016 stopped ct after 4 weeks due to adverse reaction I believe to be serotnin toxicity due to mirtazapine interaction

Escitlopram 10 mg May 2016 - cut to 5mg May 2016  stopped ct November 2016 no W/d's noted

Lyrica 300mg May 2016 - July 2017 - Taper from Jan to Jul 17 awful taper.

Lofepramine 150mg  November 2016 - January 2017 Swift w/d as it didn't work

Quetiapine 75mg November 2016 changed to 150 XL May2017 changed to 150mg IR July 2017 reduced to in 25mg steps from July to 50mg Oct 17. 37.5mg 12th Nov 17 - 35mg 20 Nov 17 - 30mg 22 Nov 17 - 25mg 24 Nov 17 dropped to 20mg Dec 17, 15mg Jan 18. Current taken at bedtime.

Quetiapine dropped Jan 17th 2018.

Dosulepin 75mg May 2017 - increased in 25mg steps to 175mg Oct 17 Reduced to 150mg Nov 17 current taken at bedtime

Diazepam 15mg May 2016 - c/t'd by shrink after 6 weeks. Reinstated at 12mg after 4 weeks June 16 - current 4mg 3 times a day morning, 2.30pm and bedtime.

Mirtazapine 15mg since March 2015 - current - pooped out within 4 weeks

Link to comment
9 minutes ago, Staz said:

Thank you Powerback,

I'm going to stop drinking today and see if it helps my depression. It's supposed to deplete serotonin so is probably working against my meds now. Hopefully a few weeks dry I should see a bit of an improvement.

replace that time you drink with something ,make it a positive action that will help recovery .go for a walk on the times you would drink .people that know I've given up drink say to me ,how do I do it ,but little do they know the fight of withdrawl is much bigger for  me.

Good luck  you'll be fine. go easy on yourself .

Alcohol free since February 2015 

1MG diazepam

4.5MG PROZAC.

 

 

 

Link to comment

I don't underestimate the amount of willpower it must have taken you. Not for one minute. Last year I went about 3 months without any alcohol and ever since it's been at a pretty low level but like you say it's replacing the time you drink with something else instead. That's the difficulty for me as I only drink in the evenings while watching TV. It's only a couple of 4% 500ml bottles of bitter but with my meds it's bad news as alcohol is cross tolerant with any benzo. When I come to my benzo taper it's got to stop and I'm sure it makes other w/d's more difficult. I'm still really struggling with my last quetiapine cut which I know I did far too quickly.

Being home all day is boring as well especially when you are in w/ds and the temptation to blot the day out is tempting although I've resisted temptation during my illness. 

Dosulepin 75mg 1996 - 1997 tapered off no problem - Prozac sporadic use between 1995 and 2011 usually 9 months then off.

Mirtazapine 2015 tapered off after 4 months no problem -Prozac 20mg 2012-2015 tapered off no problems

Prozac 20mg April 2016-May 2016 stopped ct after 4 weeks due to adverse reaction I believe to be serotnin toxicity due to mirtazapine interaction

Escitlopram 10 mg May 2016 - cut to 5mg May 2016  stopped ct November 2016 no W/d's noted

Lyrica 300mg May 2016 - July 2017 - Taper from Jan to Jul 17 awful taper.

Lofepramine 150mg  November 2016 - January 2017 Swift w/d as it didn't work

Quetiapine 75mg November 2016 changed to 150 XL May2017 changed to 150mg IR July 2017 reduced to in 25mg steps from July to 50mg Oct 17. 37.5mg 12th Nov 17 - 35mg 20 Nov 17 - 30mg 22 Nov 17 - 25mg 24 Nov 17 dropped to 20mg Dec 17, 15mg Jan 18. Current taken at bedtime.

Quetiapine dropped Jan 17th 2018.

Dosulepin 75mg May 2017 - increased in 25mg steps to 175mg Oct 17 Reduced to 150mg Nov 17 current taken at bedtime

Diazepam 15mg May 2016 - c/t'd by shrink after 6 weeks. Reinstated at 12mg after 4 weeks June 16 - current 4mg 3 times a day morning, 2.30pm and bedtime.

Mirtazapine 15mg since March 2015 - current - pooped out within 4 weeks

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