DMV64: reinstate Saphris?

[DMV64]

24 minutes ago, Rosetta said:

Maybe your other drugs will cover for any bumps post-zero!!

I hope sso too! : )

[DMV64]

@ChessieCat I’m expecting I will have symptoms like I usually do when I make any cut. But is there anything special I should look for? Like if the symptoms go on for longer than a certain amount of time do I have to reinstate or do I just hang in?

[DMV64]

@JanCarol @manymoretodays @Rabe @Roseta Day 3 since my last dose of Saphris. Definitely feeling some of the typical symptoms of cuts: anxiety in morning. Fear. Hoping I adjust soon. Xo

[JanCarol]

Hey D - congrats on the jump!!!

3 days - wayyyy toooooo sooooon to make any judgement calls.  Besides - you're gonna ride this one out, yes?  Just be patient with yourself until it settles?

Please wait before moving to the next taper.  I'm thinking at least 4 weeks after symptoms settle.  Which might be 6+ weeks from now.  That gives this time to settle, and you get a new baseline!

HOORAY = your first new baseline, Saphris free!  Coming soon to a D near you!

So - let's start discussion your options for the next taper.  Benzo?  Geodon?  Vyvanse?  Is there another one that you are already converting to liquid? Let's work this through!  You might want to do a meditation, where you take the tablets and ask your body which one it needs to be rid of first.  This polydrug stuff can be complicated - and you've had a lot going on, so enjoy this 6 week break before your next taper!

 

i've been - back to regular sun walks to fight off the black dog (it still happens, but now it happens drug free, and I am the one empowered to do something about it).  

So - I hope you see the sun today!

[Carmie]

Congratulations on being Saphris free DMV, that’s wonderful news💚

[DMV64]

8 hours ago, JanCarol said:

taper

Thanks! It’s a little rough right now. Feel pretty shaky and agitated

I believe that Shep said we should do the Geoden next. And I’m already doing that in liquid form about three times a day. So I guess that’s where we should go next? Glad you are getting sun!

[JackieDecides]

On 8/21/2019 at 4:15 AM, DMV64 said:

@JanCarol @manymoretodays @Rabe @Roseta Day 3 since my last dose of Saphris. Definitely feeling some of the typical symptoms of cuts: anxiety in morning. Fear. Hoping I adjust soon. Xo

 

 

give yourself more time, as a wise person said. congratulations on being free of the Saphris! 

[manymoretodays]

Oh DMV,

3 hours ago, DMV64 said:

Thanks! It’s a little rough right now. Feel pretty shaky and agitated

I believe that Shep said we should do the Geoden next. And I’m already doing that in liquid form about three times a day. So I guess that’s where we should go next? Glad you are getting sun!

On 8/21/2019 at 5:15 AM, DMV64 said:

Day 3 since my last dose of Saphris. Definitely feeling some of the typical symptoms of cuts: anxiety in morning. Fear. Hoping I adjust soon. Xo

 

So.......yay and controlled happy dance for you now. 💃  As this was your initial goal.......way back when and all.  So........do allow yourself to feel the pride of a job well done, and completed.  And oh my.......look how far you have come, along the way........the patience with yourself, and self care and learning.  I mean it's all rather huge.

 

And yah......bumps along the way.  And the morning, this morning of day 4, I presume,  you report shaky and agitated.  What skills, the non-drug coping ones, are you using?  A yoga stretch perhaps, or some meditation via writing in your journal or just getting right to the NOW- however you like to do that,  or a gentle walk, even weighed blanket and staying put, watching something uplifting or doing a craft,  etc.  You get my drift. 

Oh boy, seeking direction for my thoughts and feelings on awakening, is sometimes a challenge for me.......I do an easy go to of just giving thanks.......for my feet and toes, while I wiggle them, and then on upward.....Heyo......I think JC got me going with that. 🤓  And then asking the Great One to guide me and my thoughts and actions too, always, without a doubt, helps so much.

 

12 hours ago, JanCarol said:

Let's work this through!  You might want to do a meditation, where you take the tablets and ask your body which one it needs to be rid of first.  This polydrug stuff can be complicated - and you've had a lot going on, so enjoy this 6 week break before your next taper!

3 hours ago, DMV64 said:

I believe that Shep said we should do the Geoden next. And I’m already doing that in liquid form about three times a day. So I guess that’s where we should go next?

 

Cool, yes, do the meditation too, with your meds. in hand.  Geodon may be the best choice, as it's a nasty AP.........  You've got time though here, and we can review a bit. 

Enjoy your break.  I kind of want to post the "Happy" song here now, you know......... the Funk one that gets one out of their chair and smiling.

 

Oh DMV, this is all quite grand, and I am smiling with you.  😻

 

Love, peace, healing, and growth,

mmt

Edited August 22, 2019 by manymoretodays
grammar corrections

[DMV64]

54 minutes ago, manymoretodays said:

bumps

Well today I went to DBT group and I will be taking a yoga class later as well as teaching one. I do feel like I really accomplish something. But I do have another sinus infection which is really annoying since I just had sinus surgery. And then I got into a minor car accident this morning. However I’m not going to let this steal away my accomplishment

[manymoretodays]

Music what helps you, put it here

I posted 2 ^.......because I'm happy......

(it's in off topic forum, so one has to be signed in to get there)

 

Good work DMV64.

 

Make it a good one today everybody.

Edited August 22, 2019 by manymoretodays
spacing is off

[Rabe]

WOW DMV!!!  How exciting to be jumping off!  I am so excited for you that one of the drugs will be gone.  YAY!!!  You go girl!!  

Love and hugs DMV!💜

[DMV64]

52 minutes ago, Rabe said:

YAY!!!

Omg yes! Not too bad so far. Here’s hoping!

[neroli]

oh, DMV, so pleased to hear you have got one drug out of the way.  And in amazement that you are able to do a yoga class and teach one, too!  AND got to a DBT group.

 

You are doing so well.

 

lots of best wishes

 

Neroli 💜💜

[DMV64]

4 hours ago, neroli said:

You are doing so well.

Thank you I really needed that this morning. It’s rough one with some older feelings of deeper terror coming in. I hope it doesn’t last too long 

[neroli]

I hope so, too, DMV.  sending best thoughts over the water to you...

 

Neroli 💜

[DMV64]

 Hello friends. I’m just checking in because I woke up in a not a great way. I know this is going to be an up-and-down road as I have jumped off. But the depression was pretty strong this morning. Plus I was going to go to the beach and now it looks like it’s going to be cloudy there and it’s over an hour drive so I don’t think we’re going. For some reason this has hit me really hard. Also last night my husband was talking about wanting to do different things. Things that are hard for me to do right now. He says it wasn’t about me it was just about trying to check in with each other and make some plans  but I wound up feeling kind of deflated. 

[JanCarol]

Hey D - 

I am lucky in this regard.  Sometimes it seems like I have to scramble to do what hubby wants to do - like a festival at the Theatre (3 days of multiple shows), or travel.

Travel is really hard for me to say no to, because - it's paid for, so I usually kick my arse and go.  And end up having a great time.  Sometimes I return sick or have to have meltdown time - but I survive, and enjoy the experience.  I even got a wheelchair for myself so that I could do a little hiking in Tasmania.  I didn't use it every day - but it gave me rest days in between big physical days.

He's currently talking major trips like flying around the world, seeing Europe, and I'm terrified!  Right now I know it's not financially possible, so - I let him talk about it, and do not express my terror that the toilets will be unavailable, or - throneless - or - down the hall in the hotel.  Or that jet lag will make me useless for the entire trip.  Or that tours (if we take them) might wear me down, and then - I'm half the world away from my home.  Or that I might get sick, and have difficulty getting what I need.  All of these things cross my mind, but I hold my tongue, and let him talk.  (he is aware of my fears, and if I expressed them, he would do his best to accommodate).  We are not getting younger, so if we want to see England (again, for me) or Denmark, France, Germany, Iceland, Norway, Russia, Mongolia, China, Japan, Vietnam - we'd better get to it sooner rather than later.

My friend - not a psych survivor, but suffers chronic pain and fatigue  - has a husband who always wants to do active things.  Hike the Great Divide of the Rockies.  Hike the Appalacian Trail.  Bicycle to Mexico.  Walking tours of Italy and cycling around England, etc. etc.

After going along with as much as possible, she has found compromises.  She got an electric bike for some of his bike trips (and gritted her teeth over the travel - like me - survived it - and enjoyed the experience, but with less suffering because of the electric bike.  And the big one?  The big backpacking trips?  "Honey, go with your mates.  Make it a men's thing.  I'm just not strong enough to do that kind of grueling effort."  And so he went, and she gets a little rest.

You're doing just fine, be kind to yourself!

And I hope you see the sun today!

[Rosetta]

(((DMV))). I know that feeling -- suddenly realizing that something one wanted to do isn't going to happen.  It's been a shock at times because for so many years I felt nothing but relief if an outing was cancelled.  The anticipatory anxiety was so strong that I was happy if something was nixed.  Now that I feel disappointment it's surprising and the disappointment is strong.  Can you figure out a back up plan?  Something you have been hoping to do but never find the time?  It could be simple -- drive a cross town and get a certain food.  Go out tonight instead.  See a movie.  Visit a museum.  

 

The fake depression is really awful if it reminds us of the real thing, isn't it?  Maybe you are one who never had the real thing, (I can't remember) but just the memory of before stabilization must be tough to experience.  Watching a comedy or a stand up routine on Netflix often helps me.

[DMV64]

@JanCarol @RosettaYou know I really didn’t have depression like this before these meds. Sigh. 

Travel really makes me anxious. I kind of need a nap every day. My ibs might flare. I am on a taper schedule involving liquids. I never know how I am going to feel. Just going on s short day trip feels too hard. 

Camping is way out of the question. I hope it is not always like this. I would like to be more carefree

[JackieDecides]

3 hours ago, DMV64 said:

@JanCarol @RosettaYou know I really didn’t have depression like this before these meds. Sigh. 

Travel really makes me anxious. I kind of need a nap every day. My ibs might flare. I am on a taper schedule involving liquids. I never know how I am going to feel. Just going on s short day trip feels too hard. 

Camping is way out of the question. I hope it is not always like this. I would like to be more carefree

 

🙁  I believe it is temporary. I think things are getting better for all of us, but it's hard meanwhile. 

 

did your husband mean he would do things without you, instead? 

 

 how much can you talk to him about how it feels and what might make it something you can bear?  I find that planning help with anxiety - the more I know what's going to happen the easier it is.  

 

I would also like to go camping someday - but not alone so I need to meet someone I can go with! 

[DMV64]

2 hours ago, JackieDecides said:

without you,

No, he didn’t mean that. I think he just meant he would like to do more things together. I think it is hard for him. But he is very compassionate. 

I am tired a lot.  Sigh

[JackieDecides]

12 hours ago, DMV64 said:

No, he didn’t mean that. I think he just meant he would like to do more things together. I think it is hard for him. But he is very compassionate. 

I am tired a lot.  Sigh

 

that's good. I mean he wants to do more together, not that you are tired a lot.

 

it's temporary!! 

[Rabe]

Im sorry DMV...so can empathize.  I feel often that I juset cannot 'keep up' with life the way I used to.  The fears are back and the spontaneity is gone....I feel I fall short of expectations and needs often.  

On 8/25/2019 at 1:46 PM, DMV64 said:

I would like to be more carefree

I miss this SO much too!!!  Take care of you!  Hope you are feeling ok with sinuses and GI.  Take care DMV!! 💜

[DMV64]

@JanCarol I have been prescribed Uribel for my Irritable Bladder (Interstitial cystitis). I need to take something. Diet alone is not working. I am scared.What do you think?

[DMV64]

Also cog fog is very bad since jumping off Saphris. Is this a normal occurance? Like really bad. Sometimes I forget what I am doing in the middle of doing it.

[ChessieCat]

I suggest you do a drug interaction check of all the drugs and include the Uribel.  Copy and paste the results in a post.

 

Drug Interactions Checker   and/or   medscape.com/drug-interactionchecker

 

[ChessieCat]

BTW spelling is incorrect in your drug signature:  Geodon not Geoden and Omeprazole not Omezerpole

[DMV64]

I've bolded and coloured Uribel

Interactions between your drugs

Major

sodium biphosphate  ziprasidone

Applies to: Uribel (hyoscyamine / methenamine / methylene blue / phenyl salicylate / sodium biphosphate), Geodon (ziprasidone)

Ziprasidone can cause an irregular heart rhythm that may be serious and potentially life-threatening, although it is a relatively rare side effect. The risk is increased if you have low blood levels of magnesium or potassium, which can occur with bowel cleansing preparations or excessive use of medications that have a laxative effect. You should use sodium biphosphate exactly as prescribed by your doctor, and drink plenty of clear liquids before, during, and after the cleansing process to avoid becoming dehydrated. Talk to your doctor if you have any questions or concerns. Your doctor may be able to recommend specific fluids you can drink before starting sodium biphosphate to help maintain your electrolyte levels. He/she may also want to monitor your electrolyte levels and/or heart rhythm. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations during treatment with these medications. In addition, you should let your doctor know if you experience signs and symptoms of low electrolyte levels such as weakness, tiredness, drowsiness, dizziness, confusion, tingling, numbness, muscle pain, cramps, nausea, or vomiting. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Switch to professional interaction data

Major

sodium biphosphate  phenyl salicylate

Applies to: Uribel (hyoscyamine / methenamine / methylene blue / phenyl salicylate / sodium biphosphate), Uribel (hyoscyamine / methenamine / methylene blue / phenyl salicylate / sodium biphosphate)

Bowel cleansing with sodium biphosphate can cause kidney failure, in some cases up to several months after the procedure. Although it rarely occurs, the risk is increased in individuals receiving treatment with phenyl salicylate, especially if they are also elderly or frail. You may need a dose adjustment or special tests to safely use both medications. Combining these medications may also increase the risk of dehydration and electrolyte abnormalities. In severe cases, dehydration and electrolyte abnormalities can lead to irregular heart rhythm, seizures, and kidney problems. You should use sodium biphosphate exactly as prescribed by your doctor, and drink plenty of clear fluids before, during, and after the cleansing process to keep yourself hydrated. Your doctor may also recommend an electrolyte rehydration solution that you can use. Talk to your doctor if you have any concerns. It is important to tell your doctor about all other medications you use, including vitaminsand herbs. Do not stop using any medications without first talking to your doctor.

Switch to professional interaction data

Major

hydrOXYzine  ziprasidone

Applies to: hydroxyzine, Geodon (ziprasidone)

Using ziprasidone together with hydrOXYzine is not recommended. Combining these medications can increase the risk of an irregular heart rhythm that may be serious and potentially life-threatening, although it is a relatively rare side effect. You may be more susceptible if you have a heart condition called congenital long QT syndrome, other cardiac diseases, conduction abnormalities, or electrolyte disturbances (for example, magnesium or potassium loss due to severe or prolonged diarrhea or vomiting). Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations during treatment with either of these medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Switch to professional interaction data

Moderate

benztropine  clonazePAM

Applies to: Cogentin (benztropine), Klonopin (clonazepam)

Using benztropine together with clonazePAM may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Switch to professional interaction data

Moderate

hyoscyamine  ziprasidone

Applies to: Uribel (hyoscyamine / methenamine / methylene blue / phenyl salicylate / sodium biphosphate), Geodon (ziprasidone)

Using hyoscyamine together with ziprasidone may increase side effects such as drowsiness, blurred vision, dry mouth, heat intolerance, flushing, decreased sweating, difficulty urinating, abdominal cramping, constipation, irregular heartbeat, confusion, and memory problems. Side effects may be more likely to occur in the elderly or those with a debilitating condition. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Switch to professional interaction data

Moderate

hydrOXYzine  gabapentin

Applies to: hydroxyzine, gabapentin

Using hydrOXYzine together with gabapentin may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Switch to professional interaction data

Moderate

hydrOXYzine  sodium biphosphate

Applies to: hydroxyzine, Uribel (hyoscyamine / methenamine / methylene blue / phenyl salicylate / sodium biphosphate)

HydrOXYzine can cause an irregular heart rhythm that may be serious and potentially life-threatening, although it is a relatively rare side effect. The risk is increased if you have low blood levels of magnesium or potassium, which can occur with bowel cleansing preparations or excessive use of medications that have a laxative effect. You should use sodium biphosphate exactly as prescribed by your doctor, and drink plenty of clear liquids before, during, and after the cleansing process to avoid becoming dehydrated. Your doctor may be able to recommend specific fluids you can drink before starting sodium biphosphate to help maintain your electrolyte levels. He/she may also want to monitor your electrolyte levels and/or heart rhythm. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations during treatment with these medications. In addition, you should let your doctor know if you experience signs and symptoms of low electrolyte levels such as weakness, tiredness, drowsiness, dizziness, confusion, tingling, numbness, muscle pain, cramps, nausea, or vomiting. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Switch to professional interaction data

Moderate

hydrOXYzine  hyoscyamine

Applies to: hydroxyzine, Uribel (hyoscyamine / methenamine / methylene blue / phenyl salicylate / sodium biphosphate)

Using hydrOXYzine together with hyoscyamine may increase side effects such as drowsiness, blurred vision, dry mouth, heat intolerance, flushing, decreased sweating, difficulty urinating, abdominal cramping, constipation, irregular heartbeat, confusion, and memory problems. Side effects may be more likely to occur in the elderly or those with a debilitating condition. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Switch to professional interaction data

Moderate

gabapentin  ziprasidone

Applies to: gabapentin, Geodon (ziprasidone)

Using gabapentin together with ziprasidone may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Switch to professional interaction data

Moderate

clonazePAM  ziprasidone

Applies to: Klonopin (clonazepam), Geodon (ziprasidone)

Using clonazePAM together with ziprasidone may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Switch to professional interaction data

Moderate

clonazePAM  methylene blue

Applies to: Klonopin (clonazepam), Uribel (hyoscyamine / methenamine / methylene blue / phenyl salicylate / sodium biphosphate)

Using clonazePAM together with methylene blue may occasionally cause high blood pressure and flushing. Contact your doctor if you experience severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting during treatment with these medications, as these may be signs and symptoms of excessively high blood pressure. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Switch to professional interaction data

Moderate

clonazePAM  omeprazole

Applies to: Klonopin (clonazepam), omeprazole

Omeprazole may increase the blood levels and effects of clonazePAM. This can increase the risk of side effects including excessive drowsiness and breathing difficulties. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Switch to professional interaction data

Moderate

benztropine  ziprasidone

Applies to: Cogentin (benztropine), Geodon (ziprasidone)

Before using ziprasidone, tell your doctor if you are also on benztropine. You may need dose adjustments or special tests in order to safely use both medications together. You should notify your doctor if you have signs of bladder problems, dry mouth, stomach pain, fever, blurred vision, confusion, dizziness, or reduced heart rate. You should avoid driving until you know how these medications will affect you. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using your medications without first talking to your doctor first.

Switch to professional interaction data

Moderate

benztropine  gabapentin

Applies to: Cogentin (benztropine), gabapentin

Using benztropine together with gabapentin may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Switch to professional interaction data

Moderate

benztropine  hyoscyamine

Applies to: Cogentin (benztropine), Uribel (hyoscyamine / methenamine / methylene blue / phenyl salicylate / sodium biphosphate)

Using benztropine together with hyoscyamine may increase side effects such as drowsiness, blurred vision, dry mouth, heat intolerance, flushing, decreased sweating, difficulty urinating, abdominal cramping, constipation, irregular heartbeat, confusion, and memory problems. Side effects may be more likely to occur in the elderly or those with a debilitating condition. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Switch to professional interaction data

Moderate

benztropine  hydrOXYzine

Applies to: Cogentin (benztropine), hydroxyzine

Using benztropine together with hydrOXYzine may increase side effects such as drowsiness, blurred vision, dry mouth, heat intolerance, flushing, decreased sweating, difficulty urinating, abdominal cramping, constipation, irregular heartbeat, confusion, and memory problems. Side effects may be more likely to occur in the elderly or those with a debilitating condition. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Switch to professional interaction data

Minor

omeprazole  phenyl salicylate

Applies to: omeprazole, Uribel (hyoscyamine / methenamine / methylene blue / phenyl salicylate / sodium biphosphate)

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed. 

For clinical details see professional interaction data.

No other interactions were found between your selected drugs. This does not necessarily mean no other interactions exist. Always consult your healthcare provider.

Drug and food interactions

Moderate

progesterone  food

Applies to: progesterone

Grapefruit juice may increase the blood levels of certain medications such as progesterone. You may want to limit your consumption of grapefruit and grapefruit juice during treatment with progesterone. However, if you have been regularly consuming grapefruit or grapefruit juice with the medication, then it is advisable for you to talk with your doctor before changing the amounts of these products in your diet, as this may alter the effects of your medication. Contact your doctor if your condition changes or you experience increased side effects. Orange juice is not expected to interact.

Switch to professional interaction data

Moderate

hydrOXYzine  food

Applies to: hydroxyzine

Alcohol can increase the nervous system side effects of hydrOXYzine such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with hydrOXYzine. Do not use more than the recommended dose of hydrOXYzine, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Talk to your doctor or pharmacist if you have any questions or concerns.

Switch to professional interaction data

Moderate

sodium biphosphate  food

Applies to: Uribel (hyoscyamine / methenamine / methylene blue / phenyl salicylate / sodium biphosphate)

Oral medications may not be properly absorbed when they are taken within one hour before starting sodium biphosphate for bowel cleansing. Talk to your doctor or pharmacist to see if you should adjust the dosing schedule of your other medications before you begin bowel cleansing treatment. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Switch to professional interaction data

Moderate

gabapentin  food

Applies to: gabapentin

Alcohol can increase the nervous system side effects of gabapentin such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with gabapentin. Do not use more than the recommended dose of gabapentin, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Talk to your doctor or pharmacist if you have any questions or concerns.

Switch to professional interaction data

Moderate

ziprasidone  food

Applies to: Geodon (ziprasidone)

Alcohol can increase the nervous system side effects of ziprasidone such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with ziprasidone. Do not use more than the recommended dose of ziprasidone, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Talk to your doctor or pharmacist if you have any questions or concerns.

Switch to professional interaction data

Minor

estradiol  food

Applies to: Estradiol Patch (estradiol)

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed. 

For clinical details see professional interaction data.

Therapeutic duplication warnings

Therapeutic duplication is the use of more than one medicine from the same drug category or therapeutic class to treat the same condition. This can be intentional in cases where drugs with similar actions are used together for demonstrated therapeutic benefit. It can also be unintentional in cases where a patient has been treated by more than one doctor, or had prescriptions filled at more than one pharmacy, and can have potentially adverse consequences.

Duplication

Central Nervous System (CNS) Drugs

Therapeutic duplication

The recommended maximum number of medicines in the 'Central Nervous System (CNS) Drugs' category to be taken concurrently is usually three. Your list includes five medicines belonging to the 'Central Nervous System (CNS) Drugs' category:

• Klonopin (clonazepam)
• Geodon (ziprasidone)
• gabapentin
• Cogentin (benztropine)
• hydroxyzine

Note: The benefits of taking this combination of medicines may outweigh any risks associated with therapeutic duplication. This information does not take the place of talking to your doctor. Always check with your healthcare provider to determine if any adjustments to your medications are needed.

Duplication

Tranquilizers

Therapeutic duplication

The recommended maximum number of medicines in the 'tranquilizers' category to be taken concurrently is usually one. Your list includes two medicines belonging to the 'tranquilizers' category:

• Klonopin (clonazepam)
• hydroxyzine

Note: The benefits of taking this combination of medicines may outweigh any risks associated with therapeutic duplication. This information does not take the place of talking to your doctor. Always check with your healthcare provider to determine if any adjustments to your medications are needed.

 

Edited September 1, 2019 by ChessieCat
bolded and coloured Uribel

[JanCarol]

23 hours ago, DMV64 said:

@JanCarol I have been prescribed Uribel for my Irritable Bladder (Interstitial cystitis). I need to take something. Diet alone is not working. I am scared.What do you think?

 

Hey D - 

 

This is outside my range of expertise!  I don't know anyone who has taken it, nor do I know its interactions with other drugs.

If the doctors say that you need it, then take it.  When I looked it up, I learned that it is a gentle muscle relaxant, with antiseptic and pain relieving qualities.  So a brake.

But if you need it, you need it.

When in doubt, go to drugs.com

 

https://www.drugs.com/sfx/uribel-side-effects.html

Chessie's suggestion of doing drug interactions is spot on, too.

Copy / paste - if you are using a phone or tablet, I do not know.  On a PC, I highlight the text I want to copy, the either click Ctrl-V (keyboard) or right click (mouse) and select copy.

Cog fog - throughout the withdrawal process (and often for years afterwards, too) - is normal.  Sorry you are experiencing it (maybe keep up the Wim Hof?), but it will get better, especially as we get your Geodon doses down.

I hope you see the sun today!

 

 

[DMV64]

10 hours ago, JanCarol said:

Cog fog

This is encouraging! I greatly am having trouble putting things together. 

Infortunately I do need this Med. One more. Sigh. 

Thanks for the response’

[JanCarol]

19 hours ago, DMV64 said:

Major

sodium biphosphate  phenyl salicylate

Applies to: Uribel (hyoscyamine / methenamine / methylene blue / phenyl salicylate / sodium biphosphate), Uribel (hyoscyamine / methenamine / methylene blue / phenyl salicylate / sodium biphosphate)

OMG Uribel has a major interaction with Uribel!  

And it does have a major conflict with Geodon.

 

Time to go back to doc and ask for something different - this drug is in direct conflict with your cocktail.  (and, oddly, this drug is in direct conflict with itself.  Who makes these things?)

 

THanks for posting that, and I hope you see the Sun today!

[manymoretodays]

Hey guys,

I'm also seeing a Major and Moderate interaction with Vyvanse and Uribel, DMV64.

You may have forgotten to add that into your own interactions report?

Or did I miss it?  I'll add it here.

 

Major

methylene blue lisdexamfetamine

Applies to: Uribel (hyoscyamine / methenamine / methylene blue / phenyl salicylate / sodium biphosphate), Vyvanse (lisdexamfetamine)

Using methylene blue together with lisdexamfetamine is not recommended. Combining these medications can cause dangerously high blood pressure and even death. You may use lisdexamfetamine only after you have been off methylene blue for at least 14 days. You should seek immediate medical attention if you experience sudden and severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting during treatment with methylene blue, as these may be signs and symptoms of excessively high blood pressure. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

 

And comes up again as a moderate:

Moderate

methenamine lisdexamfetamine

Applies to: Uribel (hyoscyamine / methenamine / methylene blue / phenyl salicylate / sodium biphosphate), Vyvanse (lisdexamfetamine)

Methenamine may reduce the blood levels of lisdexamfetamine, which may make the medication less effective in treating your condition. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

 

Current drug list is then:  Uribel, clonazepam, Geodon, gabapentin, Cogentin, hydroxyzine, omeprazole, progesterone, and Vyvanse

(taken from your drug interaction list posted, DMV, and signature)  That's 9!!

Is this all correct?

 

And don't panic dear DMV,  I agree with JC and will add that some of your symptoms now, might very well be from 1. Saphris WD  2. adverse effects 3. drug interactions.

When you can, try and do a few logs, as to when you take all these medications.  Time on the left.  Note all meds/drugs on the right by name and with the dosages.

 

Of course you can find more on individual drug side effects/adverse reactions at Drugs.com too.  Just use the box at the top.

Hopefully, the cog-fog comes and goes.....hard to say for sure, whence that comes from now.  Self care DMV64.  I know it's tough and frustrating.......

Would a gratitude list help?  Staying just in the day as well.  Remember that " Just for Today" prose, meditation?  Oh, be kind and gentle with yourself too.

 

Best DMV, healing vibes sent,

L, P, H, and G,

mmt

 

 

Edited September 2, 2019 by manymoretodays
additional

[DMV64]

On 9/2/2019 at 12:15 PM, manymoretodays said:

gratitude

I do a gratitude list every day for five things. I’ve been doing a long time. I had to stop the uribel Because I believe is a major contributor to the cog fog 

 I’m going to be trying the over the counter AZO  instead but it’s too bad because that medicine really works for me and my bladder. I can’t really tell what’s going on because I just got off of the Saphris But I can say that it’s really intense. I’m dropping things, I can’t remember what I did earlier in the day, I’m forgetting what I was going to say next I’m forgetting my yoga sequences it’s just not good. I hope that it really is just a symptom of coming off the servers and it’s going to end. 

Thanks for writing to me Mmt

[DMV64]

I feel like I am collapsing in on myself. Yes I am on 9 drugs. Sad. 10 if you count estradiol patch. Thought I put that in there. 

I dont know. Maybe if Uribel is not causing cog fog I can take it

[JanCarol]

Hey D - 

 

I'm more concerned about the major interactions with the Uribel...than the cog fog. 

in withdrawal - and on psych drugs - and on many other drugs, too - cog-fog is a given.  It comes and goes.  Windows and waves.  I'm less worried about the cog fog (even though you are concerned) than I am the major interactions with uribel.

Is there anything else the doc can give you?  I know about the AZO, which (to me) feels pretty harmless, but only addresses symptoms - doesn't effect a "cure."  You can't keep taking it forever!

I hope you see the sun today?

[DMV64]

15 hours ago, JanCarol said:

forever!

I stopped the uribel and started up the azo again. I think it’s making me feel sick. But the uribel was resolving symptoms but making me forget everything. So tired like zombie. Doc is away another week. She had mentioned Elmiron. But it takes a couple of months to work and could make your hair fall out in patches. Ugh. Plus I have not looked up interactions. 

I am still getting bladder installation. The next step would be surgery with hydroditension and possible cauterization.

 One other option I know of is a very small dose of amyltriptilime.  

Not sure about that. I am open to ideas. Can’t take AZO forever although some on my IC board do. 

They also do this thing with high-dose antibiotics over a period of time I think the belief behind it is that the infection is embedded in the lower tissue. Some people have had success with that. 

 Then one person told me about this Doctor Who she swears saved her. I think he used  some kind of injection, commonly used for sports injuries in the joints.  I’d have to get on the board, I just don’t remember the name. He was the only doctor she could get to do it. I think he’s in Boston. I would go up there for it but I need a little more information