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Weight gain, weight loss, appetite changes, hunger

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Meimeiquest

Throwing randomly...I have been reading of oxidative stress lately. It could gum up your mitochondria so they can't make energy. You might try careful vegetable juicing. Ending with every disclaimer possible.....

 

There is a man in Nashville who claims to have cracked the code on weight loss...John Jubilee. His insights on "cellular transformation" are super-protected for his clients, his fee is $3000. He claims a 100% success rate, money back guarantee. Which beats suicide.

 

Speaking of which, such a strong reaction might be worth looking into.

 

Really wishing you the best!

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Nikki

High estrogen and high testosterone will cause a big weight gain.....how was your progesterone? 

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Finn

I actually lost weight when I was on ads, and I was very rarely able to lose anymore than a few pounds before this time. Or at least I lost when I was on Zoloft/ Effexor. When I bridged to Prozac and started tapering that is when I noticed the gain. But it could be unrelated since I have unstable blood sugar, high male hormone levels, insulin resistance. My gain was enough that my endocrinologist noticed. I didn't mention to her anything about ad withdrawal or my theory on cortisol. I'm monitoring my weight now, though, and if it continues to go up, I'll have to talk to my endo about it.

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jnahas

Does anyone have experience with bloating caused by withdrawal?  I too am gaining weight, but my diet and exercise routine hasn't changed.  I've been celexa free for 2 weeks (I did tapered but probably should have done it more slowly) and up 5 pounds.  Is this withdrawal?  Does it get better?  Is there anything I can do?  The only additional issue I have is intense lower back pain if anyone has dealt with that one, I'd love advise!

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Jemima

Both being on antidepressants and withdrawing from them can upset a person's metabolism so that they gain weight without changing their eating or exercise habits. You still have time to reinstate Celexa (about thirty days from stopping the drug, or about two weeks in your case) and I recommend that you do that, although at a lower dose than what you were taking, perhaps 10%.  If that's enough to stabilize, you can then set about tapering off gradually and slowly which will give both your body and your brain time to adjust.

 

It would help us to help you if you'd post an Introduction in the 'Introductions and updates' discussion area and include your psychiatric drug history in the signature. Here's how: http://survivingantidepressants.org/index.php?/topic/893-please-put-your-withdrawal-history-in-your-signature/

 

Welcome to the forum, jnahas.  You'll find lots of good information and friendly support here. 

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Newbeginning

Does anyone have experience with bloating caused by withdrawal?  I too am gaining weight, but my diet and exercise routine hasn't changed.  I've been celexa free for 2 weeks (I did tapered but probably should have done it more slowly) and up 5 pounds.  Is this withdrawal?  Does it get better?  Is there anything I can do?  The only additional issue I have is intense lower back pain if anyone has dealt with that one, I'd love advise!

 

The 5 pound gain was after the 2 weeks on celexa or after a few weeks off celexa? Depending on how fast you gained the weight, it could be a number of things, including SSRI use/withdrawal. Have you had a medical check? Hormonal problems or health problems that result in abnormal water retention could also cause rapid weight gain.

 

Best of luck.

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Newbeginning

KS1994,

 

I didn't realize you had replied with more information. I think your hormones being out of whack is defintely an issue that could be causing the weight gain.

 

Please don't despair. Suicide is a permanent solution and what you're facing is a temporary problem that has a solution. You have things that you can try, such as bio-identical hormones. Work with the new endocrinologist. Don't give up.

 

Remember that your weight or your physical appearance are not everything that defines you or gives you value as a person. Think of how many people love you regardless of your appearance, and how many you love, regardless of their appearance.

 

Things will get better. Don't lose hope.

 

If you would like to talk, please send me a PM.

 

Wish you strength and peace. You're in my prayers,

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Donna1960

Hi there, it is really interesting to find out that someone else is suffering the same as I am.

 

I have gained 20kg and growing since starting to come off my medication 10 months ago and am at my wits end to understand why.  While on them I lost the same 20kg without any extra effort on my part and nothing has changed regarding my eating and exercise patterns.  I may be wrong but the only thing I can tie it to is the medication.  I have been a weightwatchers member for years and eat/exercise accordingly.

 

I have spoken with my doctor, been for tests which all came back normal.  I am beginning to wonder if it is the cortisol thing.  I presume the medication would have reduced the levels and that would have been why I lost the weight.  Now I have come off it the cortisol has returned to previous levels and therefore the weight has come back on.

 

Any ideas would be appreciated.

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LRG

I'm so glad I found this forum because most everything I read countermands what I am experiencing.  I went off Lexapro after more than a decade on antidepressants.  I tapered off slowly, did everything right, and I am now having horrendous post-med symptoms.  First, I've had a rebirth of all the menopause symptoms I missed out on 15 years ago: night sweats, flushes, flashes, just awful.  Then, I seem to be gaining about a pound a day.  Also, my already nasty bowel problems are getting worse.  I'm seeing the doctor, this week, but I'm really having trouble living with the symptoms. 

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UselessSpork

Anyone notice the pounds flying off after withdrawing from mirtazapine/remeron? What does mirtazapine do that effects your weight? aside from making you have more of an appetite.

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ten0275

Well, for me - esepcially when I first started taking the Mirt - I had the munchies that would rival any college frat brother/sister on a stoned Friday night with the smell of saucy, cheesy pizza and breaded, slightly seasoned mozzarella sticks in the air.... That tempered itself the longer I took it, but it always stimulated my appetite. So calorie intake increased, which of course is going to promote weight gain.

 

I also theorize that it does something metabolically that affected fat stores, but I am uncertain of the science behind this. That said, I am on 1.9mg now and maintain a good body weight with exercise - but do expect some loss after total cessation from the Mirt.

 

Hang in there.

 

Dave

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UselessSpork

Well, for me - esepcially when I first started taking the Mirt - I had the munchies that would rival any college frat brother/sister on a stoned Friday night with the smell of saucy, cheesy pizza and breaded, slightly seasoned mozzarella sticks in the air.... That tempered itself the longer I took it, but it always stimulated my appetite. So calorie intake increased, which of course is going to promote weight gain.

 

I also theorize that it does something metabolically that affected fat stores, but I am uncertain of the science behind this. That said, I am on 1.9mg now and maintain a good body weight with exercise - but do expect some loss after total cessation from the Mirt.

 

Hang in there.

 

Dave

Ahh yeah, when i first started i wanted to eat everything. But the appetite calmed down after a while.. although i still retained a higher weight than normal, despite not eating **** tons. So i think you may be right, it might be effecting some part of your metabolism and fat stores. Right now i will admit im eating less (trying to avoid sh*tty foods more) but it's not enough to warrant the crazy weight loss. Hopefully i can start gaining weight again soon, not really a fan of being skeletor lol.

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Lily777

Hi all,  I am new here and am very grateful for all the advice and great posts.   I am wondering if anyone else had weight gain with cymbalta?    I have only been on it for 6 months,  and I have gained weight steadily.   Along with severe bloating and constipation.  Frankly I am miserable.  Help please.

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ang

Just wanted to start a topic here.  Like I was panicking about having no appetite, now i am in WD.....and eating perhaps two pieces of toast per day... other days are better.

Well I got over panicking, I will not starve.  Before Antidepressants use I was thin, the usual me... my sister convinced me I was too thin, so antidepressants, and yes, got so fat my legs rubbed together!  

Well now i just accept that my body is healing, now I am off these evil drugs.  My legs no longer rub together, but still my real me.... my real inner me,.... my natural body seems to think I am fat... My natural body is reducing rapidly to the "normal for me"....  so I just take this symptom of having no appetite, as my body going back to the normal for me.

Anyone else panic about not eating  ""enough"..............?????????????  

I aint worried anymore, and nice to see my thin body returning...  I am thin, naturally a skinny person.......  I was well until someone convinced me I was too thin... judgements, judgments...

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ten0275

ang, hey.

 

this does freak me out. i lost so much weight in benzo withdrawal, it truly scared me. i was, at certain points, eating less than 300 calories a day and having daydreams about being delightfully over-weight. i had to keep my pants tied up with a rope. i was really freaked about the weight thing.

 

i fear the same thing at times now with my continued withdrawal from mirtazapine. so far, the appetite issue hasn't become a problem. i know it could, but it hasn't. i'll cross that bridge if and when i have to. this time, i would probably opt to force-drink whey protein shakes with full fat milk.

 

it's true. we will not starve. but still unsettling when the appetite evaporates.

 

so you are definitely not along in getting freaked out by this.

 

hang in there.

 

dave

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sunflower

Hi,

 

My appetite is very poor and it is freaking me out!

 

Does anyone know why our appetite is negatively affected during WD?

 

Sunflower

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wantrelief

I have this problem too - I have been losing a lot of weight (and have in the past with various failed attempts at withdrawing from ADs).  Food just doesn't appeal to me, nothing sounds good (which is so not me).  The weird thing is that despite having no appetite, I have been forcing myself to eat pretty much what I would have eaten before going through WD and I am still losing weight.  It feels like anxiety is making me burn more calories or something.  I also haven't been sleeping very well and wonder if just being up when I would have been sleeping is burning more calories.  I don't know…..whatever the cause it does distress me.  It is so ironic as I hated the weight I gained from ADs but I hate losing it in this unhealthy way at the same time.  I also get upset if someone mentions my weight.  The other day someone said I was shrinking and it freaked me out.  :(

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ten0275

Hello, this response pertains to Sunflower's query about why appetite is negatively affected in withdrawal.

 

I have read that with both Benzos and ADs, there are receptor sites for both GABA and serotonin in the gut as well as the brain. So just as the hobbled receptors in the brain cause issues, so do those in the gut. There have been many articles written about the connection between gut health and mental health. The gut is sometimes referred to as "the second brain."

 

Hang in there.

 

Dave

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AliG

Mirtazapine is the same as Mianserin.  Huge appetite, zombie- if you like sleeping till 12md. No life.

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AliG

I haven't seen anything on this , here, but I am finding it increasingly difficult to control my weight. I know SSRI's are notorious for weight gain as a side effect, and I did put on some weight on some of them, no matter how hard I tried not to. The thing is I've noticed that even when I've stopped the medication, I'm still gaining. I had a break from A/D's for 8 months and still struggled, to lose the weight. This time , it seems even worse. It's not diet or exercise, as I do that. It's like the body has a mind of it's own. Is it possible that the metabolism gets affected long term? I would love to hear from anyone who is having the same issues, or if anyone has been through this and has advice to share on how to lose resistant weight.

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FatPaxiller

When I originally went on SSRI's back in 2008 (Prozac) I was very slim. Within about 8-10 months I was up a whole dress size and bigger than when pregnant. I never ate more that is guaranteed. I then switched to Citalopram 2 years ago and gained a further 3lbs, then after 5 months I suffered depersonalisation and switched to Paroxetine and gained 12lbs more.

Nobody in the world can convince me that these do not alter metabolism. I have been drug free now for almost 11 months and have lost 7lbs. I feel better physically (although I feel depressed still, but I'm managing without A/D's even though I never thought that was possible).

I have been told that if I never ate more it must be because of my age, but nobody gains 12lbs in as many months, twice due to 'age' (I'm currently 26 and my family are skinny). I still have a lot of weight to lose, but from what I've read it can take upto 2 years to even start coming off (I noticed my loss in December, so almost 8 months off, literally dropped off although I haven't lost any since).

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JanCarol

I was always athletic, running, cycling, skating, weightlifting, skiing, hiking, backpacking.  I was always slim and fit.  5'8", 125 lbs.  And strong, with endurance.

 

I am no longer.  I started to have some metabolic issues after trying this or that SSRI and finally settling on Wellbutrin - but it was also accompanied by stress.  I knew I would not lose any weight.  I took out a bet with a head of the corporate fitness center where I worked - he said that if I followed his 1500 calorie diet and exercised exactly as he told me, I would lose weight.  I laughed.  6 weeks later, I was a lot more fit from all the cardio and aerobic and weightlifting etc. (that was when we were just discovering that weightlifting increases metabolism, too), but not a pound lost - while on Wellbutrin which is sometimes prescribed for weight loss!

 

I even took up smoking for 10 years to try and lose a little.  I think I lost 5 pounds, then gained it back - and then I had a smoking habit to deal with.

 

It was only downhill from there.  I can't say what role SSRI's, tricyclics, lithium, and even seroquel have played on my metabolism.  But I suspect I will have to be 3-5 years on the other side of withdrawal to see if I can make a difference.  I also suspect I will have to deal with stress, and trauma, as I wonder how much I am protecting myself from intimacy by being fat, ugly, and uncomfortable.  (don't try to cheer me up on that one, it's what I see in the mirror at this point in time, it may be that my attractiveness, appearance, has been destroyed as karma for the way I lived much of my life!)

 

So yes - I believe that pscyh drugs can ruin the gut, and can contritube to metabolism problems.  Neuroleptics seem to just slow the whole system down, while SSRI's - the withdrawal period could deregulate you (and your gut) and cause you to retain weight.  We retain weight in stress.

 

And that's the other side of the picture.  There are a number of reasons, patterns, beliefs which contribute to keeping weight.  Stress is a huge one. We tend to use it as protective armor against all kinds of stress.  

 

So the drugs don't help, but it's not clear enough (except in the case of neuroleptics, where it's been proven) to point the finger and say "THIS is the cause!"  There are other contributing causes, as well.

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peggy

i initially lost weight on effexor - i was around 57kg (125 lbs) now i am 66kg (145lbs) - whilst that is still in a healthy weight range for my height of 168cm (5 ft 6") i eat far less than i used to.  So, my weight gain has been a slow creep - probably a kg a year after the first few years on effexor.  It is MUCH harder to lose weight for me - almost impossible.  But, how much of this is due to menopause is debatable as well....

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AliG

If you read some of the depression forums, which i did before I found this one, you will find so many people struggling with huge weight gains,


 


that just don't make sense. the thing is some of them have been off the drugs for years and still can't lose the weight. I'm talking about people who are


 


hitting the gym big time, dieting religously  and doing all the right things.  I have found the same thing myself. During the 8 months, I was off everything,


 


I continued to gain. Ther was no rhyme or reason  to it . No matter what I did or do now, it just keeps piling on. I am very strict with myself. It's not like i sit around


 


eating cream buns.  I agree with "FatPaxiller'' that nothing will convince me that this poison doesn't alter metabolism. It alters everything else, that it stands


 


to reason it would affect that as well.  I'm desperate to lose this drug weight. If anyone has any ideas , that would be great.


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JanCarol

There are many of us in this boat.  And it is not helped by the fact that intense exercise is activating and off the menu for many of us.

 

At least we are not alone?  What is the weight limit on this boat?   :o

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chicken

I never gained weight on an SSRI but I did gain on Remeron. I was underweight and that was a plus for me. Now that I'm off Remeron I don't notice too much of a change in my weight. I think I eat a  little less but still more than I did before Remeron. I don't know how long this will last or if it is permanent. I don't want to go back to being underweight but I'm past 40 now the weight might stay anyway with or without a drug.

 

I'm tapering a tricyclic now and it doesn't appear to affect my appetite and the weight is staying the same. If the anxiety comes back I know my weight will drop as anxiety keeps me from eating.

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FatPaxiller

Another thing I find peculiar and I'm sure a few others will too, is the possibility that depression/anxiety causes an individual to lose there appetite and when taking antidepressants, the mood lifts and appetite increases (or returns to normal). I am an emotional eater, always have been, so I should have lost weight on antidepressants, another thing I sincerely cannot understand. Toward the end of my time on A/D's I was eating the healthiest I ever have, I no longer drink alcohol and we are financially struggling so eating out is rare too.

Also, the way I see it if weight gain was caused by additional eating, wouldn't this say so on the list of side effects rather than putting weight gain alone?

Either way, I have lost weight without trying and people have noted that my face also looks slimmer. I have read other websites when I was deciding whether to stay on meds or not and quite a few people claim the weight eventually 'dropped off'. The question is, "when"?

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MatGMax

I'm down to 2mg (from 20mg) over the last 2 years.

I'm starting to lose weight, but it is taking time.

And a lot of exercise!

At the moment I'm running 15 km a week and riding 30 km a week.

 

But exercise can be tricky.

It has taken me 4 months to build up any sort of tolerance to running.

At first I could only run 20 metres before getting puffed out.

 

Cheers

 

Damien

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Addax

This is purely anecdotal, but I'll put it out there anyway....

 

SSRIs appear to suppress our ability to feel satiated, while also increasing our craving for carbohydrates. For some I think the craving of alcohol is linked into this. So hungrier and craving carbs can obviously contribute to weight gain.

 

Serotonin plays a role in carbohydrate metabolism, which is likely why some people crave carbs... I'm not sure how it relates to weight gain or fat storage directly but I do know that people react differently to the amount of carbs in their diet. Calorie deficit is the rule of thumb for weight loss, however, ratio of carbs:fat:protein can still play a role as far as I'm aware, and the "beneficial" ratio can be different for different people. It may have more to do with satiety and energy level then actual fat loss, but again, I'm not sure. In any event, given the impact SSRIs seem to have on carbohydrate metabolism, and from what I've read, a high carbohydrate diet maybe beneficial. I know high protien is touted as the gold standard in many circles, but I just read something about that kind of diet being contraindicated for people taking SSRIs for the reasons I mentioned above.

 

Of course candy, cakes, and cookies are not the sort of carbohydrates I'm referring to, in fact sugar seems to exacerbate some symptoms associated with cortisol. But vegetables, grains, legumes, those kind of carbs are good sources. I'll see if I can dig up sources, but it's food for thought in the meantime (I swear the pun was not intended!!).

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AliG

LOL. Addax!   I agree with you , though, there seems to be some discrepancy,  to do with  mood and diet.  There's one camp, that says high protein, high fat diet is  the way to go , given that the brain is made of fat and thrives on fat.  (Grain Brain  by  Dr David Perlmutter).  Then there's the other camp, that says,  carbohydrate is the bomb!!    ( "Potatoes not Prozac". )    It's confusing , as are most things, these days, but I can't help thinking the high " animal protein "   craze , ( paleo) , is being driven by the food industry, just the same way, as the "Pharmaceuticals"!!   Follow the money!!

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dalsaan

Weight gain is notorious on mirtazapine. I think there are two key mechanisms at play. First it makes you very hungry and not for lettuce. Secondly it slows down your metabolism. So it's a double whammy.

 

The only time I have lost weight is through a very low carb diet of about 1500 calories per day coupled with exercise 6 days a week.

 

It's possible but challenging

 

D

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AliG

You're right Dalsaan, they slow down the metabolism.  I was only on Mirtazapine for less than a week, and I could see the writing on the wall, for weight gain.  My appetite had a mind of it's own.  The thing is, how long does this messed up metabolism, stick around?  Not only that , but the high cholesterol, Pre-diabetes, high blood pressure, messed up liver enzymes, and  thyroid issues.

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AliG

It seems to be drug weight , that won't shift. No exercise or diet, works. The metabolism is altered. I hope it's not permanent!!

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Addax

Ha! Potatoes not Prozac. That's funny! I hadn't heard that before. It makes sense since our brain runs exclusively on glucose (except in starvation). I'm wary of the claims in Grain Brain because there's been so much of criticism of the authors claims... And because of the low carb diet money train it rides, as well as what you mentioned :-).

 

I think it comes down to how the food makes you feel and given the serotonin role with carb metabolism there's been speculation that a diet higher in carbohydrates might be the way to go. Weightloss is the result of creating a calorie deficit. Manipulating the macros may help maintain muscle mass during weightloss and stuff like that, but I don't think they play a direct role in losing or maintaining actual body weight.

 

I hadn't realized meds had been shown to actually slow down metabolism. That's awful... I hate theses drugs so much.

 

So far as diet and macros t's probably different for different people for any multitude of reasons. One thing that I think can probably be agreeded on across the board is that dieting sucks!

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AliG

I Addax, it's a book. can't remember the author , but if you google it , it will come up.It does sound funny. I agree.  The other thing I agree with you is that dieting sucks I agree that it's how it makes you feel and at the moment I want to eat to feed my brain, but the thing is I'm carrying what I call "drug weight" and I also have high cholesterol (from the drugs), so I feel torn between the plant based, high carb diet and the high protein (paleo) diet.  Sometimes there is just too much information, and too much disagreement , from the so - called experts, it is hard to sort out. You have to be a detective these days, with everything.  It does your head in.

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