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Using a digital scale to measure doses

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brassmonkey

Considering that you have just started to taper the small variations in pill weight shouldn't make any difference for quite some time.  If you are doing a 10% Brassmonkey Slide you should be getting down to 15mgai in about nine months.  When you get to that level you will need to be paying closer attention to the small variations, but even then two or three milligrams pill weight shouldn't make much difference.  I'm not saying to be sloppy in making up your doses, but rather to not obsess over it quite yet.

 

So we can do some quick calculations what is the average weight of one of your pills? We usually use 10 pills to determine the average weight. I am assuming that the 30mg is the strength listed on the package.

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PerAsperaAdAstra
On 3/29/2020 at 9:01 AM, brassmonkey said:

Considering that you have just started to taper the small variations in pill weight shouldn't make any difference for quite some time.  If you are doing a 10% Brassmonkey Slide you should be getting down to 15mgai in about nine months.  When you get to that level you will need to be paying closer attention to the small variations, but even then two or three milligrams pill weight shouldn't make much difference.  I'm not saying to be sloppy in making up your doses, but rather to not obsess over it quite yet.

 

So we can do some quick calculations what is the average weight of one of your pills? We usually use 10 pills to determine the average weight. I am assuming that the 30mg is the strength listed on the package.

 

Sorry for my late reply! Haven't seen you've replied until now. You're right about the 30 MGAI being the amount on the package. I started with that amount on 28 March.

I also read your advice about taking the average of 10 pills instead of 1, which I've applied.

 

According to the calculations in Excel I will be at 15,94323 MGAI at the beginning of December. At that moment I'm sort of 8,3 months tapering already. 9 months and 15 MGAI would therefore make sense. This reassures me I'm properly doing the Brassmonkey Slide. Thanks for providing these metrics to gauge I'm not doing any stupid things.

 

I've heard that below 20 MGAI (or somewhere thereabouts) one would need to be a little bit more careful because of the exponential effects tapering a certain amount has, right?

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brassmonkey

If you look at the SERT Occupancy chart http://www.mediafire.com/view/opcitwztcu1x3sb/5HTT_occupancy_curve_-_clomipramine_and_fluvoxamine.jpg it really brings the taper into prospective.  Any dose over 20mgai is pretty much wasted as it has very little affect. Between 20 and 10mgai there are noticeable differences with each reduction and from 10mgai on down things happen quickly with each reduction.  Our recommended 10% reduction plan and the Brassmonkey Slide have a reduction rate that pretty well matches the same curve. 

 

Because of this curve it is quite important to do reductions on  a percentage basis instead of by a set weight.  The set weight would give a straight line instead of a curve and an accelerating amount of reduction. The percentage base taper will match the curve and give a smaller decrease each reduction cycle making things much easier on the body.

 

In theory on can reduce a bit faster between 20mgai and 10mgai has to slow up a bit from 10mgai to 5mgai and then take things very carefully below that.  In practice it works better to take it slow and steady the entire way.  Even though the occupancy rate can be matched there are a lot of other things going on that need time to heal also.  If these are rushed then they have a bad tendency to build up and eventually cause a crash.  That crash can take months to stabilize and frequently leaves a person sensitized so they have to proceed with even more caution.

 

What is the average weight of one of your tablets? Who is the manufacturer?

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PerAsperaAdAstra
19 hours ago, brassmonkey said:

If you look at the SERT Occupancy chart http://www.mediafire.com/view/opcitwztcu1x3sb/5HTT_occupancy_curve_-_clomipramine_and_fluvoxamine.jpg it really brings the taper into prospective.  Any dose over 20mgai is pretty much wasted as it has very little affect. Between 20 and 10mgai there are noticeable differences with each reduction and from 10mgai on down things happen quickly with each reduction.  Our recommended 10% reduction plan and the Brassmonkey Slide have a reduction rate that pretty well matches the same curve. 

 

Because of this curve it is quite important to do reductions on  a percentage basis instead of by a set weight.  The set weight would give a straight line instead of a curve and an accelerating amount of reduction. The percentage base taper will match the curve and give a smaller decrease each reduction cycle making things much easier on the body.

 

In theory on can reduce a bit faster between 20mgai and 10mgai has to slow up a bit from 10mgai to 5mgai and then take things very carefully below that.  In practice it works better to take it slow and steady the entire way.  Even though the occupancy rate can be matched there are a lot of other things going on that need time to heal also.  If these are rushed then they have a bad tendency to build up and eventually cause a crash.  That crash can take months to stabilize and frequently leaves a person sensitized so they have to proceed with even more caution.

 

What is the average weight of one of your tablets? Who is the manufacturer?

 

Massive thanks for the information brassmonkey! This is of great help! 🙂

I am now even more resolved to do it by the book, easy as she goes. But good to know where I need to start paying extra attention to reductions. I sure want to prevent stuff from building up too much, thereby sensitizing the CNS.

 

The tablets are from Aurobindo. One pill (30 MGAI, based on the average of 10 pills) weighs somewhere between 0,3663 mg and 0,3684 mg. The measurements differ however, but slightly.

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brassmonkey

Thanks for the numbers Per they really help.

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PerAsperaAdAstra

I'm pretty lucky I'm not in serious withdrawal atm and can wrap my head around your instructions easily. 

(and it helps I'm well versed in Excel :-P)

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phillyfan24

@brassmonkey

quick question regarding crushing the pills and using the scale. I am using trintellix, which has a film coating. Is this something to worry about? I am obv not getting the same amount of coating in each capsule. Should I avoid the coating all together when filling my capsules? I really want to make sure I’m doing things consistently. I am at the high dose as of now and think it may make more of a difference as I get lower 

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brassmonkey

Consistency is a major key to a successful taper. The actual dose doesn't matter, but rather getting as close to the same dose as possible each time. Does the coating grind to a powder when you crush the pills?  If so try to mix it in as best as you can and not worry about it.  If it stays in big sheets then try to remove as much of the powder as possible from each piece and then discard the pieces of film.  The physical weight of the skin will be so small it's not going to change the dose unless you get big chunks of it at one time.

 

When working with powder/crushed pills and scales the weight of original pile of powder doesn't matter, It is basically a stockpile that you draw a specific weight out of. The weight you are measuring on the scale is the important one. I usually rushed up three or four pills at a time in one pile so I would have enough to work with.

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Timberline

Hi @brassmonkey...just started crushing pills to get ready for taper. I weighed 20 pills and got a weight of 2.581 grams. I divided that number by 20 and got .129 grams as an average weight per pill. I crushed up one pill and weighed the powder and got a weight of .089. With my first 10% cut, I will need a weight of .116 of powder. It seems as if I'll run out of my RX quicker, if it takes about 1 and 1/2 pills to get the correct weight of powder for 1 dose. Am I looking at this correctly?

 

Thanks!!

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brassmonkey

Interesting.  I can see a few milligrams being lost, maybe four or five, but 40 is quite a lot. The crushed tablet should have the same weight as the whole one. Have you tried it again and gotten the same result? How are you crushing them?

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Timberline

Thanks @brassmonkey... I'm using this: https://www.amazon.com/gp/product/B01MZ04NWS/ref=ppx_yo_dt_b_asin_image_o07_s00?ie=UTF8&psc=1

It's crushes it in to a very fine powder and some gets left behind when I pour the powder out on to the scale. It's impossible to scrape the film of powder left behind. Maybe I should crush with a spoon instead?

 

I didn't want to try it again until I heard some suggestions... didn't want to risk losing another dose!

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brassmonkey

Yea, I'd try the two spoon method. Work over a piece of paper to catch any that falls and put a small piece of paper with a fold in it on the pan of the scales. The spoon method can leave things a little course, I just would put it on the paper and crush it some more with one spoon against the table top. When you measure out the dose be sure to save the leftovers, you end up getting "a free dose" that way.

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