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The antidepressant effectiveness controversy (UK)


peng
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After speaking on the phone to the practice manager of the health centre of our town, she passed me her email (not available on website, by the way - it does not seem to encourage emails, surprise, surprise) and, apparently sympathetic and understanding, she agreed to circulate this link among our GPs.  I have been using this health centre since 1978.  Currently, and for the last couple of years, my GP is supporting my attempted tapering down of the beast that is Effexor.

 

Our GPs are mostly very good to us, but, it is clear to me, that they are firefighting and do not have the resources available to get people like us, support from, say, nutritionists and other potentially useful therapists.  Nor do they have the lived experience so many of us have acquired.

Here's hoping actions like this can someday help other desperate, suffering folks.   

 

At almost 73 I am not at my peak, but if even I can do this, perhaps many others can, too - maybe we can help turn the tide?

 

I have to confirm at this point that I am only doing this after gaining knowledge myself, through research, and that includes visiting the wonderful survivingantidepressants.org site, its admirable moderators, leader and fellow sufferers.

 

 

http://cepuk.org/2018/03/01/royal-college-psychiatrists-challenged-burying-inconvenient-antidepressant-data/

 

 

 

 

 

 

 

 

Born 1945. 

1999 - First Effexor/Venlafaxine

2016 Withdrawal research. Effexor.  13Jul - 212.5mg;  6Aug - 200.0mg;  24Aug - 187.5mg;  13Sep - 175.0mg;  3Oct - 162.5mg;  26Oct - 150mg 

2017  9Jan - 150.00mg;  23Mar - 137.50mg;  24Apr - 125.00mg;  31May - 112.50mg holding;  3Sep - 100.00mg;  20Sep - 93.75mg;  20Oct - 87.5mg;  12Nov - 81.25mg;  13 Dec - 75.00mg

2018  18Jan - 69.1mg; 16Feb - 62.5mg; 16March - 57.5mg (-8%); 22Apr - 56.3mg(-2%); CRASHED - Updose 29May - 62.5mg; Updose - 1Jul - 75.0mg. Updose - 2Aug - 87.5mg. Updose - 27Aug - 100.0mg. Updose - 11Oct 112.5mg. Updose - 6Nov 125.00mg

2019 Updoses 19 Jan - 150.0mg. 1April - 162.5mg. 24 April - Feeling better - doing tasks, getting outside.  7 May - usual depression questionnaire gives "probably no depression" result.

Supps/Vits  Omega 3;  Chelated Magnesium;  Prebiotics/Probiotics, Vit D3. 

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Things have moved apace in that a formal complaint has now been lodged with the Royal College of Psychiatrists against its President Wendy Burn and the chair of its Psychopharmacology Committee Professor David Baldwin. They are charged with misleading the public over claims that AD withdrawal resolves within 2 weeks when on the RCPsych own website - document has subsequently been removed - they acknowledged that within their survey group anxiety lasted more than 12 weeks.

 

https://www.madinamerica.com/2018/03/formal-complaint-uk-royal-college-psychiatrists-2/ 

 

Professor John Read discusses the formal complaint with James Moore on his podcast.

 

https://www.madinamerica.com/2018/03/professor-john-read-royal-college-psychiatrists-antidepressant-withdrawal/  

1979 put on Clomipramine.
Failed attempt to withdraw from Clomipramine started on Seroxat 1992.
1997 Effexor replaces Seroxat after failed withdrawal.
2011 fail to withdraw from Effexor despite combined use of Prozac and Seroquel. Started on Cymbalta.
Anxiety not resolved by Cymbalta so taper off by 28th March 2012. Left on 10mg Buspirone and 1 quarter of 5mg Diazepam.
Anxiety at times very severe. 19th May take my first half of a 5mg Lamictal.

As of 5/11/2013, off all psychiatric drugs. Doing better but hope for more healing yet.

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I am new here and just reading this. The complaint letter is fantastic. I am in the US and am embarrassed to say work in healthcare. Unfortunately our medical system is ruled by money. No one will sponsor a study to prove withdrawal symptoms exist because it would mean losing $ by big pharma. And, big pharma unfortunately sponsors way too much research. I have lost complete faith in our medical system. Follow the money..sad

Start citalopram late 2004 20 mg/d, tapered to 10 mg 1xd on for several years

Citalopram 5 mg 1xd, occasional attempt to taper; off citalopram 4 months Aug. 2016

Venlafaxine 37.5 mg 2 months Nov, Dec 2016 stopped ct and change to citalopram 10 mg/d severe withdrawal with daily nausea 

Citalopram 20mg/day April 2017 - Feb 21, 2018, Citalopram 15 mg/day Feb. 21 - 3/3/2018

Citalopram 20 mg/day 3/4/18, Citalopram 18 mg 1xd 3/5 - 4/1,

Citalopram 17 mg 4/2, 16.6 mg 4/16, 16.2 mg 4/23, 16 mg 5/14, 15.8 mg 5/18, 15.6 mg 5/22, 15.4 mg 5/29, 15.2 mg 6/5, 15 mg 6/12,

14.6 mg 7/21, 14.2 mg 7/28, 14 mg 8/4, 13.6mg 8/18, 13.2 mg 8/25, 13 mg 9/1, 12.6 mg 9/22, 9/25 13 mg, 11/9 12.8 mg, back to 13 mg after a few days. 1/9/19 12.8 mg, 1/14 12.6 mg, 1/20 12.4 mg, 1/27 12.2mg, 2/4 12 mg, 2/24 11.8 ,3/1 11.6, 3/6 11.4, 3/11 11.2, 3/14 11, by 4/28 10 mg.

Nov. 1 9.8 mg, Nov 8 9.6 mg, Nov 22 9.5 mg, slow taper down to 9 mg 1/27/2020. Slow taper down to 8 mg Sept 1 2020, decrease by approx. 10% a month to 5 mg/day Jan. 2021.

 

Supplements/other: multivitamin, vitamin d 2000 u 1xd,, melatonin 0.75 mg mg 1xd prn, magnesium, Propranolol Sr 60 mg/day Feb. 2016 (?), alprazolam 0.125 mg prn  (rarely taken) approx. <2 yrs 

Change to famotidine 20 mg prn, cetirizine 10 mg prn or loratadine 10 mg prn for allergy sx.

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Agree. 

 

2001 Remeron , Celexa, prozac a week on lithium. 

2014 went off effexor and trazadone in 3 weeks. 

2014 zoloft (hyper reaction) put on effexor 75 mg. Was stable until 2017 

2017  Trazadone 50 mg (June) Effexor to 113 mg (2 weeks) Effexor 150 mg for a month . Took 75 mg until November. . Lithium 10 days, Lamactil 10 day  aug-nov15 ativan

October : Prozac bridge to get off 75 mg of effexor Used 10 mg of prozac. Stopped prozac 3 wk 

Dec 6, 7 Upped trazadone from 50 to 100 mg Did it for 3 days Stopped it

Dec 7 , Dec 8 Took prozac again 0.1 , 0.1, 0.6 stopped it

Dec 11 and Dec 12 upped it to 100 again

Dec 15 , 16,17 went back to 50 mg of trazadone

December 18 Began 3 beads of effexor  Dec 25 began 5 beads of effexor take 10 mg of omneprazole daily

 

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  • ChessieCat changed the title to The antidepressant effectiveness controversy (UK)

Hi all, just wanted to mention that action has recently been taken in Australia and New Zealand too, here is the letter from a group of six doctors and psychiatrists to the Royal Australian and New Zealand College of Psychiatrists:

 

https://www.madinamerica.com/2018/03/letter-royal-australian-new-zealand-college-psychiatrists/

 

March 2012 - Prescribed Mirtazapine 15mg for anxiety and phobias

May 2012 - Jan 2017 - Had several brief spells on 30mg, none helpful, remained at 15mg

May 2017 - Started my withdrawal by transferring to liquid preparation at the same dosage (1ml = 15mg)

 

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  • 2 months later...

@JamesMoore was there a response?

2005 St John's Wort / 2006-2012 Lexapro 20mg, 2 failed attempts to stop, tapered over 4.5 months in early 2012

January 2013 started Sertraline, over time worked up to 100mg

July 2014 Sertraline dropped from 100mg to 75mg, held for six months, slower tapering until 2019 22 Dec 3.2mg

2020 Sertraline 19 Jan 3.1mg, 26 Jan 3.0mg; 1 Mar 2.9, 7 Mar 2.8, May (some drops here) 24 May 2.5, May 29 2.4, June 21 2.3, June 28 2.2mg,  July 4 2.1mg, July 24 (or maybe a bit before) 2mg, early Nov switched to home made suspension; 29 Nov 1.8mg; approx 25 Dec 1.6mg)

2021 Some time in about Jan/Feb realised probably on more like 1.8mg and poss mixing error in making suspension; doses after 10 Feb accurate; 10 Feb 1.6mg; 7 Mar 1.4, continued monthly

10% drops until 1mg, then dropped 0.1mg monthly.

May 2022,0.1mg, now dropping 0.01mg per week

My thread here at SA: https://www.survivingantidepressants.org/topic/1775-bubbles/page/18/

CurrentSertraline: 0.08mg / Armour Thyroid

 

 

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Hi @bubbles there has been a response to the UK letter, which, as you can imagine, was not in any way satisfactory, we wrote this up here: 

 

https://www.madinamerica.com/2018/05/royal-college-dismisses-complaint/

 

and I was fortunate to get to chat to John Read about this for the podcast too:

 

https://www.madinamerica.com/2018/05/professor-john-read-uk-royal-college-psychiatry-dismisses-complaint/

 

as for the letter to the RNZACP, I don’t think there has been a formal response yet, but the author of the complaint, Psychiatrist Niall McLaren wrote this rather brilliant article recently:

 

https://www.madinamerica.com/2018/05/questioning-integrity-psychiatry/

 

I will try to remember to update this thread when there is more news, I’m forgetting all sorts at the moment, I blame the withdrawal!

 

 

 

 

March 2012 - Prescribed Mirtazapine 15mg for anxiety and phobias

May 2012 - Jan 2017 - Had several brief spells on 30mg, none helpful, remained at 15mg

May 2017 - Started my withdrawal by transferring to liquid preparation at the same dosage (1ml = 15mg)

 

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Thanks @JamesMoore

2005 St John's Wort / 2006-2012 Lexapro 20mg, 2 failed attempts to stop, tapered over 4.5 months in early 2012

January 2013 started Sertraline, over time worked up to 100mg

July 2014 Sertraline dropped from 100mg to 75mg, held for six months, slower tapering until 2019 22 Dec 3.2mg

2020 Sertraline 19 Jan 3.1mg, 26 Jan 3.0mg; 1 Mar 2.9, 7 Mar 2.8, May (some drops here) 24 May 2.5, May 29 2.4, June 21 2.3, June 28 2.2mg,  July 4 2.1mg, July 24 (or maybe a bit before) 2mg, early Nov switched to home made suspension; 29 Nov 1.8mg; approx 25 Dec 1.6mg)

2021 Some time in about Jan/Feb realised probably on more like 1.8mg and poss mixing error in making suspension; doses after 10 Feb accurate; 10 Feb 1.6mg; 7 Mar 1.4, continued monthly

10% drops until 1mg, then dropped 0.1mg monthly.

May 2022,0.1mg, now dropping 0.01mg per week

My thread here at SA: https://www.survivingantidepressants.org/topic/1775-bubbles/page/18/

CurrentSertraline: 0.08mg / Armour Thyroid

 

 

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