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killme: off mirtazapine


killme

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Hi Altostrata thank you for this info. I have just discovered these forums and had not heard of the 10% rule until now.

 

I was on mirtzapaine for about a year and got up to a very high dose of 60mg. It did not help me and I should have been taken off it much earlier instead of increasing the dose higher and higher.

 

Over the last few months I've been trying to taper off it by increments of 7.5mg. Since then I've been getting this horrific feeling of being electrocuted just as I'm about to fall asleep, and am punched awake again. It's left me desperately wanting to sleep but afraid of sleep at the same time because that moment when you're about to nod off then ZAP.

 

I reduced my dose lower and lower and towards the end I sped up my tapering rather than slowing it down as I couldn't stand the zaps and just wanted this toxic **** out of my body. It would have been well over 10% of that dose. I had nobody to guide me through this and didn't realise that at lower doses you need to taper extra slow, not faster. I realise I've been showing all the signs of somebody who's extra sensitive to dose reductions.

 

Now my sleep is even worse than before I started taking antidepressants. I have lost the ability to sleep altogether. No matter what I do, I'm awake all night, and am still getting the zaps. I've been feeling so hopeless I want to die. I often have to take sleeping pills to get any sleep at all, but they usually only give me about 3 hours, a little less. I don't want to get hooked on another drug and then go through this nightmare withdrawal thing all over again.

 

I don't know what to do. What would you suggest? Is it worth getting back on it or just trying to ride this out? Have I done permanent damage to my brain? I need help

 

Edited by ChessieCat
added spacing

Escitalopram: late 2016 - early 2017
Olanzapine 5mg: started for two months in 2017, discontinued and am currently taking again
Abilify 5mg: one week in late 2017
Valium: occassionally
Mirtazapine: 2017 with gradual increasing to 60mg - tapered off at 7.5mg every few weeks. Insomnia and zaps continuing
Temazepam: occasionally
Other meds taken for short periods (up to a few months): Seroquel, Sertaline, Fluoxetine, Fluvoxamine, Zyban, Valdoxan
July 2022: Effexor for a few weeks- 37.5mg. Vyvanse 15-30mg for a few days.

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  • Administrator

Welcome, killme.

 

I moved your post to start your Introductions topic. You can post questions about your situation and track your progress in this topic.

 

How long have you been clear of mirtazapine? Do you have any mirtazapine left?

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

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Thanks for such a quick reply Altostrata! I took my last dose of mirtazapine almost a week ago. I still have plenty of tablets left, I haven't thrown out the packs yet. 

Escitalopram: late 2016 - early 2017
Olanzapine 5mg: started for two months in 2017, discontinued and am currently taking again
Abilify 5mg: one week in late 2017
Valium: occassionally
Mirtazapine: 2017 with gradual increasing to 60mg - tapered off at 7.5mg every few weeks. Insomnia and zaps continuing
Temazepam: occasionally
Other meds taken for short periods (up to a few months): Seroquel, Sertaline, Fluoxetine, Fluvoxamine, Zyban, Valdoxan
July 2022: Effexor for a few weeks- 37.5mg. Vyvanse 15-30mg for a few days.

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  • ChessieCat changed the title to killme: off mirtazapine
  • Moderator Emeritus

Hi killme and welcome from me too,

 

We ask all members to create a drug signature.  This appears below every post you make.  Please update it whenever you make a change.  This is the preferred format which makes it easier for us to see your drug history at a glance:

 

A request: Would you summarize your history in a signature - ALL drugs, doses, dates, and discontinuations & reinstatements, in the last 12-24 months particularly?

  • Please leave out symptoms and diagnoses.
  • A list is easier to understand than one or multiple paragraphs. 
  • Any drugs prior to 24 months ago can just be listed with start and stop years.
  • Please use actual dates or approximate dates (mid-June, Late October) rather than relative time frames (last week, 3 months ago)
  • Spell out months, e.g. "October" or "Oct."; 9/1/2016 can be interpreted as Jan. 9, 2016 or Sept. 1, 2016.
  • Link to Account Settings – Create or Edit a signature.

Please DO NOT TAG me - thank you

PLEASE NOTE:  I am not a medical professional.  I provide information and make suggestions. 

  MISSION ACCOMPLISHED:    (6 year taper)      0mg Pristiq      on 13th November 2021

ADs since ~1992:  25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq:  50mg 2012, 100mg beg 2013 (Serotonin Toxicity)  Tapering from Oct 2015 - 13 Nov 2021   LAST DOSE 0.0025mg

Post 0 updates start here    My tapering program     My Intro (goes to tapering graph)

 VIDEO:   Antidepressant Withdrawal Syndrome and its Management

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  • Administrator

The zaps were indications you were tapering too fast.

 

What kind of sleeping pills are you taking, and how often?

 

If I were you, I would try 5mg mirtazapine again. We call this a reinstatement. This topic explains how to take a small dose:

 

Tips for tapering off Remeron (mirtazapine)

 

About reinstating and stabilizing to reduce withdrawal symptoms

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

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I'm so lucky to have found this forum. Thanks for the links. Altostrata the sleeping pills are temazepam 10mg. I try to take them sparingly, but the last few nights I've been taking them each night as I can't sleep at all and am sick of it.

Escitalopram: late 2016 - early 2017
Olanzapine 5mg: started for two months in 2017, discontinued and am currently taking again
Abilify 5mg: one week in late 2017
Valium: occassionally
Mirtazapine: 2017 with gradual increasing to 60mg - tapered off at 7.5mg every few weeks. Insomnia and zaps continuing
Temazepam: occasionally
Other meds taken for short periods (up to a few months): Seroquel, Sertaline, Fluoxetine, Fluvoxamine, Zyban, Valdoxan
July 2022: Effexor for a few weeks- 37.5mg. Vyvanse 15-30mg for a few days.

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It's hard to divide the mirtazapine tablet into such small doses

Escitalopram: late 2016 - early 2017
Olanzapine 5mg: started for two months in 2017, discontinued and am currently taking again
Abilify 5mg: one week in late 2017
Valium: occassionally
Mirtazapine: 2017 with gradual increasing to 60mg - tapered off at 7.5mg every few weeks. Insomnia and zaps continuing
Temazepam: occasionally
Other meds taken for short periods (up to a few months): Seroquel, Sertaline, Fluoxetine, Fluvoxamine, Zyban, Valdoxan
July 2022: Effexor for a few weeks- 37.5mg. Vyvanse 15-30mg for a few days.

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6 hours ago, killme said:

It's hard to divide the mirtazapine tablet into such small doses

Hi Killme,

Ask your doctor to prescribe a 15mg SolTab mitrazapine. It is a dissolvable tablet. Dissolve 15mg tablet in 15mls of water, ( get a medicine cup), and withdraw with the syringe 5mls.

That is how I am tappering.

Don't lose hope,  it will be alright. 

Take care,  Hopefull. :)

DRUG HISTORY:

 

November 2013- Zoloft, ( Bad reaction).

January 2014 - March 2014 Seroquel.( Quit Cold Turkey).

January2014- Mirtazapine, I was taking 15mg at one stage, reduced to 7.5mg, Pgad reactions to Mirtazapine. Doctor kept increasing it to 37.5mg, until July 2014. No improvement, experiencing panic attacks, on 37.5 mg. I had enough by October 2014. Began tapering.

October 2014- Started tapering Mirtazapine from 37.5mg.

September 2015- Down to 4mg of Mirtazapine. Crashed.

September 16th- Up dosed to 5mg. Held this dose for almost 5 months. Stabilised.

February 2016- Began tapering again. From 5mg to 4.5mg of Mirtazapine. (Rocking the boat, again)! Lol. :(

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  • Moderator

HI Killme

Do not be scared my friend. I swear there life after this.

I had the same electroshocking feeling you are describing at my worse moments. I slowly tapered mirtazapine and now i am getting my life back. Not exactly as before yet but a lot better.

Follow the advice of Altostrada just start some small amount of mirt around 5Mg and keep at it until you stabilize your sleep. Later you can taper using the 10% rule. 

All the best

Santino

 

2015 -  2016 Xanax only rescue doses of 0.125 mg 1-2 times per month
 March 2016 0.125Mg * 2 Xanax for 10 days.

20 March 2016 0.25 Mg * 2 Xanax for one week. 1 April 2016 Tranxene 5 mg and Fevarin but bad reaction for 5 days.4 April 2016 25 Mg Amitryptiline + 6 MG bromazepam at night

Started tapering Bromazepam 6 days later reached up to 3 MG in 10 days and withdrawal. Pdoc asked to go 6 MG again.

10 of May started Remeron 15 MG and started tapering Bromazepam again.

SINCE 09/06/2016 BENZO FREE - Started Tapering Remeron 04/07/2016

 

04/Jul/16 12.8 Mg, 11/Aug/16 12 Mg, 20/Aug/16 11Mg, 3/Sept/16 10Mg, 11/Sept/16 9 Mg, 30/Sept/16 8.1 Mg, 14/Oct/16 7.25 Mg, 17/Nov/16 6.7, 23/Nov/16 6.5, 2/Dec/16 6.25, 9/Dec/16 6Mg, 25/Dec/16 5.7Mg, 4/Jan/17 5.4Mg, 20/Jan/17 5.2Mg, 07/Feb/17 5 Mg, 15/Feb/17 4.8Mg, 27/Feb/17 4.5Mg, 15/Mar/17 4.2Mg, 23/Mar/17 4Mg, 1/Apr/17 3.7Mg, 14/Apr/17 3.4Mg, 27/Apr/17 3.1Mg, 06/May/17 2.8Mg, 22/May/17 2.6Mg, 31/May/17 2.3Mg 09/Jun/17 2Mg, 20/Jun/17 1.7Mg, 29/Jun/17 1.4Mg, 11/Jul/17 1.2Mg, 20/Jul/17 1Mg, 31/Jul/17 0.8Mg, 11/Aug/17 0.6Mg, 23/Aug/17 0.5Mg, 05/Sept/17 0.4Mg, 13/Sept/17 0.3Mg. 22/Sept/17 0.2Mg, 03/Oct/17 0.15Mg, 10/Oct/17 0.1Mg, 23/Oct/17 0.05Mg, 22/Nov/17 0.025Mg, 06/DECEMBER/2017 MIRT FREEE.

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The difference between 7.5 mg and 0 mg, and say, 30 and 22.5 mg, is enormous. 7.5 mg of mirtazapine is extremely potent. Huge occupancy of H1R occurs at this dose. For reference H1R is completely saturated at 15 mg.

 

Just getting to 7.5 mg is like stage 1 of the withdrawal. Stage 2 is 7.5 mg to 0, which can take a while. This is just my opinion as someone who is currently tapering mirtazapine and was also taking 60 mg upon a time.

April / 2016: Cipralex 10 mg, Mirtazapine 30 mg, Lyrica 600 mg, Diazepam 20 mg, Bystolic 5 mg

2018: Lots of polypharmacy which is undocumented here. Started and stopped several drugs and changed doses of existing ones

August / 2018: Back on track! Cipralex 15 mg, Mirtazapine 7.5 mg, Diazepam 15 mg

September 2018: Cipralex 15 mg -> 12.5 mg

October 2018: Cipralex 12.5 mg -> 10 mg, Mirtazapine 7.5 mg -> 3.75 mg -> Stopped, Diazepam 15 mg

November 2019: Cipralex 5 mg, Diazepam 10 mg

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19 hours ago, Hopefull said:

Hi Killme,

Ask your doctor to prescribe a 15mg SolTab mitrazapine. It is a dissolvable tablet. Dissolve 15mg tablet in 15mls of water, ( get a medicine cup), and withdraw with the syringe 5mls.

That is how I am tappering.

Don't lose hope,  it will be alright. 

Take care,  Hopefull. :)


Thanks Hopefull, that is a good idea to use a dissolvable tablet and dropper.

Escitalopram: late 2016 - early 2017
Olanzapine 5mg: started for two months in 2017, discontinued and am currently taking again
Abilify 5mg: one week in late 2017
Valium: occassionally
Mirtazapine: 2017 with gradual increasing to 60mg - tapered off at 7.5mg every few weeks. Insomnia and zaps continuing
Temazepam: occasionally
Other meds taken for short periods (up to a few months): Seroquel, Sertaline, Fluoxetine, Fluvoxamine, Zyban, Valdoxan
July 2022: Effexor for a few weeks- 37.5mg. Vyvanse 15-30mg for a few days.

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15 hours ago, degen12 said:

The difference between 7.5 mg and 0 mg, and say, 30 and 22.5 mg, is enormous. 7.5 mg of mirtazapine is extremely potent. Huge occupancy of H1R occurs at this dose. For reference H1R is completely saturated at 15 mg.

 

Just getting to 7.5 mg is like stage 1 of the withdrawal. Stage 2 is 7.5 mg to 0, which can take a while. This is just my opinion as someone who is currently tapering mirtazapine and was also taking 60 mg upon a time.


God it's such a long, tedious process!!!! I can't believe doctors can get away with prescribing this ****. I had no idea it would be such a problem to get off, and it didn't even help me. 

Can someone tell me will these zaps ever go away? Or has this drug and the way I've tapered it sentenced me to a life of torment? I didn't realise the zaps I was getting all along were signs I was tapering too quickly.

I took half a 15mg tablet (so 7.5mg) again last night. Would this be ok or should I go get a prescription for a dissolvable tablet right away so I can make it 5mg? I was able to sleep again at last.... I suspect discovering these forums and knowing I'm on the right track and under the right guidance now helped. 

Escitalopram: late 2016 - early 2017
Olanzapine 5mg: started for two months in 2017, discontinued and am currently taking again
Abilify 5mg: one week in late 2017
Valium: occassionally
Mirtazapine: 2017 with gradual increasing to 60mg - tapered off at 7.5mg every few weeks. Insomnia and zaps continuing
Temazepam: occasionally
Other meds taken for short periods (up to a few months): Seroquel, Sertaline, Fluoxetine, Fluvoxamine, Zyban, Valdoxan
July 2022: Effexor for a few weeks- 37.5mg. Vyvanse 15-30mg for a few days.

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I found out there is a name for the zaps I'm getting: "sleep myoclonus" 

https://www.ninds.nih.gov/Disorders/Patient-Caregiver-Education/Fact-Sheets/Myoclonus-Fact-Sheet

Escitalopram: late 2016 - early 2017
Olanzapine 5mg: started for two months in 2017, discontinued and am currently taking again
Abilify 5mg: one week in late 2017
Valium: occassionally
Mirtazapine: 2017 with gradual increasing to 60mg - tapered off at 7.5mg every few weeks. Insomnia and zaps continuing
Temazepam: occasionally
Other meds taken for short periods (up to a few months): Seroquel, Sertaline, Fluoxetine, Fluvoxamine, Zyban, Valdoxan
July 2022: Effexor for a few weeks- 37.5mg. Vyvanse 15-30mg for a few days.

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  • 1 month later...

Hi killme, how are you doing? I just wanted to chime in that the normal 15 mg tablets appear to dissolve in water just fine. 

HopefulOne1

History:

Zyprexa 5mg (21JUL18) ☹️

Mirtazapine 7.5mg (19FEB18), raised to 15mg (20MAR18)

==> taper started; 14mg (23APR18)....9.5 mg (12MAY18)...7.5 mg (02JUN18)...6 mg (23JUN18)....stopped CT (21JUL18)

- Xanax 0.5mg 4-5 days/wk for ~10 yrs; reduced to 2-3 days/wk (19JAN18)

- Lexapro 20mg for ~10 yrs; ~6wk fast taper, last pill 13MAR18

- Provigil 200mg for ~10yrs; quit ct AUG 2017

- ~10 yrs of Prozac, Zoloft & Wellbutrin (not at same time) prior to Lexapro but don’t remember lengths of time or doses.

- Supplements: morning - kelp (iodine), VitD / evening - fish oil, mag gly, fiber 

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Hi killme,

 

I'm checking in to see how you are doing.   I'm currently tapering mirtazapine from a 15 mg dose.   I'm now down to 4.8 mg after 4 months and I found I need to take it much more slowly than I have at the lower doses.  I tapered at about 25% of the current dose the first 4 months and am now going to taper at 10% of the current dose every 3-4 weeks here on out.   The goal is to have minimal or no withdrawal systems.   

 

Hang in there.  You can do this!   I hope and pray the best for you.

2010:  Escitalopram (Lexapro) 10 mg.   Mirtazapine (Remeron) 15 mg. 

2011:    Tapered Mirtazapine: 5 month successful taper.  Then tapered Lexapro:  4 month successful taper

May 2011 to August 2017:   No medications, full recovery

September 6, 2017:  started Mirtazapine (Remeron) 15 mg  - due to severe sudden insomnia (I believe caused by statin use)

November 16, 2017:   started Escitalopram (Lexapro) 10 mg

January 1, 2018 to October 30. 2020 -- 34 month taper off of Mirtazapine 15 mg to 0.00 mg

June 16, 2018:  Started slow taper of 10 mg Escitalopram (Lexapro)

Current (mgai):    0.23 mg  Escitalopram

Supplements:  Fish Oil, Curcumin, bio active B vitamins, zinc, magnesium glycinate, Vitamin D, Vitamin C, saffron, citrus bergamot, ashwagandha

 

"Therefore do not worry about tomorrow, for tomorrow will worry about itself. Each day has enough trouble of its own."  Matthew 6:34

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  • 4 years later...

I had a really bad experience with mirtazapine. I have been off mirtazapine for years and still get the feeling of being electrocuted when I'm about to fall asleep at night. I am really concerned about these zaps I hear are common with effexor. My plan was to try 75mg for maybe 2 months and if I see no improvement then wean off the drug. Has anyone got the zaps from only a couple of months on effexor and at a relatively low dose? Will it leave me permanently scarred like the mirtazapine did?

Escitalopram: late 2016 - early 2017
Olanzapine 5mg: started for two months in 2017, discontinued and am currently taking again
Abilify 5mg: one week in late 2017
Valium: occassionally
Mirtazapine: 2017 with gradual increasing to 60mg - tapered off at 7.5mg every few weeks. Insomnia and zaps continuing
Temazepam: occasionally
Other meds taken for short periods (up to a few months): Seroquel, Sertaline, Fluoxetine, Fluvoxamine, Zyban, Valdoxan
July 2022: Effexor for a few weeks- 37.5mg. Vyvanse 15-30mg for a few days.

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  • Moderator

Previous post moved to your intro topic to keep your history all in one place.  Please post questions and discussion about your situation in this one thread, to avoid confusion and duplication of efforts.  Thank you.  

Do not private message me. Please do not tag me unless it's an urgent question about tapering or reinstating.

 

***Please note this is not medical advice.  Discuss any decisions about your medical care with a doctor who understands psych meds and how to withdraw from them, if you can find one.

 

Lexapro   Started Apr 15 '2010 - 10 mg;  Apr 2 '20  0.18 mg; Jul 16  0.17 mg, Aug 23  0.16 mg, Oct 7  0.15 mg, Nov 8 - 0.14, Jan 16 '21 - 0.13, Feb 7 - 0.12, Feb 22 - 0.11, Mar 26 - 0.10, May 21 - 0.09, June 15 - 0.08 Aug 16 - 0.07, Oct 6 - 0.06, Nov 21 0.05, Dec. 17 0.04, Jan 14 '22 0.03, Feb 19 0.02, Apr 18 0.01, May 15 0.005,  Jul 8, 0.00.  Psych Drug Free as of July 8, 2022!!  Woohoo!!!

other meds: Levothyroxine 75 mg

magnesium in small amounts at 4 AM, 3 PM, before bed

suppl AM: fish oil, flax oil, vit C, vit E, multivitamin, zinc

suppl 8 PM: magnesium 350 mg, GABA 750 mg, Estroven, melatonin 2 mg

 

Paxil 2002 - 2010, switched to Lexapro 

Trazodone 50 mg. 2002 - 2019, fast tapered in 2019 

Xanax 0.5 mg as needed 2002 - 2019, up to 3x weekly 

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  • Moderator Emeritus

Q:  Have you taken any other psychiatric drugs in the 4 years since you last posted.  If yes, please update your drug signature.

 

Q:  Do you drink alcohol?  If you do, then you might consider abstaining for a few months to see if that makes any difference.

 

SA is a site for reducing/going off psychiatric drugs, not about what drug to try next.

 

There is no way to know what taking Effexor will do.

 

The effect that taking psychiatric drugs has on the nervous system is cumulative so you do need to take your drug history into account.

 

75mg Effexor is NOT a low dose.  Your nervous system may be sensitised and taking this dose might make things worse.  When trying anything new, even a supplement, SA suggests only trying a small amount to test to see how you react to it.

 

Please note that it can take as little as 1 month for the brain to fully adapt to getting a drug.  After that time you would need to taper it.  You might be able to do a fast taper, but at the 2 month mark a slower taper would probably be needed, so you could end up taking longer to get off the drug than the length of the trial period.

 

Post #1 of the following has links to various helpful information, includes to the tips for tapering various drugs and how to get non standard doses.

 

Important topics in the Tapering forum and FAQ 

 

Please DO NOT TAG me - thank you

PLEASE NOTE:  I am not a medical professional.  I provide information and make suggestions. 

  MISSION ACCOMPLISHED:    (6 year taper)      0mg Pristiq      on 13th November 2021

ADs since ~1992:  25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq:  50mg 2012, 100mg beg 2013 (Serotonin Toxicity)  Tapering from Oct 2015 - 13 Nov 2021   LAST DOSE 0.0025mg

Post 0 updates start here    My tapering program     My Intro (goes to tapering graph)

 VIDEO:   Antidepressant Withdrawal Syndrome and its Management

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Is it possible to get zaps/bad withdrawals from being on effexor for only a few months and at a relatively low dose e.g. 75mg?

Escitalopram: late 2016 - early 2017
Olanzapine 5mg: started for two months in 2017, discontinued and am currently taking again
Abilify 5mg: one week in late 2017
Valium: occassionally
Mirtazapine: 2017 with gradual increasing to 60mg - tapered off at 7.5mg every few weeks. Insomnia and zaps continuing
Temazepam: occasionally
Other meds taken for short periods (up to a few months): Seroquel, Sertaline, Fluoxetine, Fluvoxamine, Zyban, Valdoxan
July 2022: Effexor for a few weeks- 37.5mg. Vyvanse 15-30mg for a few days.

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Posted (edited)

Effexor

 

Hi, so I was on this forum years ago as I was having trouble getting off mirtazapine. I felt like I was being electrocuted just when I was about to fall asleep at night and would jerk awake. This STILL hasn't gone away completely! I am still severely depressed and have now been prescribed effexor. I am really concerned about these brain zaps I hear are common with effexor and how hard it is to get off it. I have tried so many antidepressants and none have helped. I was hoping this one might be able to help me but now I don't know if it's worth it? My plan was to try 75mg for maybe 2 or 3 months and if I see no improvement then wean off the drug. Is it possible to get the zaps/bad withdrawals from only a couple of months on effexor and at a relatively low dose? Will it leave me permanently scarred like the mirtazapine did?

 

Edited by ChessieCat
added Intro topic title before merging with intro topic

Escitalopram: late 2016 - early 2017
Olanzapine 5mg: started for two months in 2017, discontinued and am currently taking again
Abilify 5mg: one week in late 2017
Valium: occassionally
Mirtazapine: 2017 with gradual increasing to 60mg - tapered off at 7.5mg every few weeks. Insomnia and zaps continuing
Temazepam: occasionally
Other meds taken for short periods (up to a few months): Seroquel, Sertaline, Fluoxetine, Fluvoxamine, Zyban, Valdoxan
July 2022: Effexor for a few weeks- 37.5mg. Vyvanse 15-30mg for a few days.

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It is absolutely possible. I’m not saying it is definitely gone by to happen, but it sure can. I missed a dose about a month after I first started on 37.5 and got the zaps and withdrawal symptoms. 

Effexor XR 75mg start June 2017

Tapered to 0 April 19-August 23/19

reinstated 1.65 mg Oct 23, updosed again to 3.35mg Oct 31/19

currently 3.35mg/day, reinstated up to full 75mg dose by February 2020

Tapered from April 2019 - August 2019 by removing beads from each capsule, i now realize that even though it may have seemed slow at the time, it wasn't!

Restarted taper from 75mg November 2021 via bead counting

currently sitting at 37.5mg

Klonopin - 1mg start January 2017, currently 0mg

Tapered down via liquid titration from Nov 2017 to Feb 2019, no withdrawals at all as I went super slow and steady.

Currently - Synthroid for under active thyroid

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  • Moderator Emeritus
Posted (edited)

I was taking Pristiq / desvenlafaxine which is a cousin of Effexor / venlafaxine.  When I missed a dose I would get brain zaps.  Once I missed 2 doses and the brain zaps were so bad that even lying down with my eyes closed if I moved my eyes without opening then I would get a zaps and a horrible sickening/nauseous feeling.  Once I took my dose and it had a chance to take effect then the brain zaps went so it was definitely the missed dose/s that caused it.

 

Edited by ChessieCat

Please DO NOT TAG me - thank you

PLEASE NOTE:  I am not a medical professional.  I provide information and make suggestions. 

  MISSION ACCOMPLISHED:    (6 year taper)      0mg Pristiq      on 13th November 2021

ADs since ~1992:  25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq:  50mg 2012, 100mg beg 2013 (Serotonin Toxicity)  Tapering from Oct 2015 - 13 Nov 2021   LAST DOSE 0.0025mg

Post 0 updates start here    My tapering program     My Intro (goes to tapering graph)

 VIDEO:   Antidepressant Withdrawal Syndrome and its Management

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  • Administrator

@killme withdrawal symptoms are a risk from any antidepressant taken for 30 days or longer. We cannot advise you what drug to take to treat your depression.

 

If your "severe depression" is emotional anesthesia, it's very possible it's an aftereffect of going on and off the antidepressants and other psychiatric drugs you've taken since 2016. Many people here have experienced this. It can last years, and very gradually goes away without further drug treatment. See

 

Derealization or Depersonalization

 

Overwhelmed, demotivated, apathetic? Cannot get going on interest or action

 

Apathy, anhedonia, emotional numbness, emotional anesthesia

 

Non-drug techniques to cope with emotional symptoms

 

Journaling / Journalling / Writing therapy / Therapeutic Writing

 

Withdrawal dialogues and encouragement

 

"Is it always going to be like this?"

 

The importance of recognizing you're feeling good

 

"Forest bathing" reduces cortisol, aids mood, immune system

 

Easing your way into meditation for a stressed-out nervous system

 

Music for self-care: calms hyperalertness, anxiety, aids relaxation and sleep

 

Shame, guilt, regret, and self-criticism

 

Health anxiety, hypochondria, and obsession with symptoms

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

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  • 1 month later...

Hi all, thank you for the replies. I stayed on Effexor for a month at 37.5mg (well actually a little less than that- I dropped down to two of the three beads inside the capsule). Not long after I started the Effexor I started getting this tingling, vibrating sensation on my scalp. Sometimes it feels like something is crawling through my hair. It's always in the same spot. I put up with it as I was starting to feel better mentally, especially when another doctor diagnosed me with ADD and prescribed a stimulant Vyvanse. But apparently I was TOO good. I became manic, which I loved, but then it all turned so horrible. I started getting panic attacks, dissociating really badly, having an existential crisis and the doctors even think I was psychotic. I ended up in hospital. In hospital they took me straight off the Effexor without weaning. I have been off it for about a month now but my scalp is still vibrating. It is upsetting me so much I want to die. I'm so scared that it will never go away and the Effexor has scarred me for life now. Does anyone know what it might be? It was kinda there before I went off the Effexor so not sure if it's just the withdrawals. 

Escitalopram: late 2016 - early 2017
Olanzapine 5mg: started for two months in 2017, discontinued and am currently taking again
Abilify 5mg: one week in late 2017
Valium: occassionally
Mirtazapine: 2017 with gradual increasing to 60mg - tapered off at 7.5mg every few weeks. Insomnia and zaps continuing
Temazepam: occasionally
Other meds taken for short periods (up to a few months): Seroquel, Sertaline, Fluoxetine, Fluvoxamine, Zyban, Valdoxan
July 2022: Effexor for a few weeks- 37.5mg. Vyvanse 15-30mg for a few days.

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This all sounds like the after effects of taking psychiatric medication.  I’m sorry for all the things that have happened to you and that you are feeling depressed and in despair. It is very frightening but people do recover from this, it’s just it can take a long time. Alto has give you some useful links, so do have a look and try some things suggested. You might like to read some success stories of people who have healed where you will see people do recover from symptoms like yours. 

 

Medications may make some people feel better for some time, but in the long run they are bad for our brains and we have to learn to live without them if we want to be fully healthy.

 

You say you were still experiencing zaps after stopping the mirtazepine, then a doctor prescribed Effexor to an already sensitised and upset nervous system, further disturbing the balance your brain was trying to achieve. Brain zaps are a common withdrawal effect and will subside over time. It is important that your brain has time to sort out the chemicals it has had disrupted.  Adding any other drugs to your nervous system will likely disrupt things further and could prolong your suffering. I know it is horrible right now and you are suffering and you want things to be better. Unfortunately the only thing we know of that makes things better is time and stability. 

 

There is a talk later today that you might find helpful, if you are feeling up to it:

 

Edited by ChessieCat
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Take part in a study about tapering - www.tapersafer.org
 

I am not a medical professional. I provide information and make suggestions based on my own experience and SA guidelines. I am unable to respond to private messages. 

Mirtazepine 15mg Nov 2018 -April 2019

April - Sept 2019 Mirtazepine down to around 6mg - skipping days to taper

October 2019 - Dec 2019 unwell from failed taper including jumping about in doses 

15 December 2019 to 13 June 2021 back to 15mg Mirtazepine 

14 June 2021 started brass monkey Slide.  
2021: 23 August 12.3mg, 28 October 11.1mg, 6 Dec 10mg

2022: 12 Feb 8.5, 25 Oct 4.5mg

 

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  • Administrator

@killme Effexor and Vyvanse do not appear in your signature. Please update your signature.

 

8 hours ago, killme said:

I put up with it as I was starting to feel better mentally, especially when another doctor diagnosed me with ADD and prescribed a stimulant Vyvanse.

 

During what period were you taking Effexor with Vyvanse, at what dosages?

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

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  • 3 weeks later...

Thanks Faure. I want to be off everything but my sleep has been horrendous so I am taking 5mg of olanzapine. My case worker thought it may even help with the vibration sensation, which he thought might be a tactile hallucination. I doubt it, they seem to be interpreting everything through the lens of psychosis now. The sensation is still there. I think the Effexor has ***** up my nerves. 

Altostrata, I was only taking Effexor with Vyvanse for a couple of days. I was prescribed 30mg of Vyvanse and took half that for a few days, then took the full 30mg and that is the day I ended up in hospital. At this time I was taking a small dose of Effexor- two of the three beads in the 37.5mg capsule.



 

Escitalopram: late 2016 - early 2017
Olanzapine 5mg: started for two months in 2017, discontinued and am currently taking again
Abilify 5mg: one week in late 2017
Valium: occassionally
Mirtazapine: 2017 with gradual increasing to 60mg - tapered off at 7.5mg every few weeks. Insomnia and zaps continuing
Temazepam: occasionally
Other meds taken for short periods (up to a few months): Seroquel, Sertaline, Fluoxetine, Fluvoxamine, Zyban, Valdoxan
July 2022: Effexor for a few weeks- 37.5mg. Vyvanse 15-30mg for a few days.

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2 hours ago, killme said:

I was prescribed 30mg of Vyvanse and took half that for a few days, then took the full 30mg and that is the day I ended up in hospital. At this time I was taking a small dose of Effexor- two of the three beads in the 37.5mg capsule.

 

I am utterly confused. Neither Vyvanse nor Effexor appear in your signature. I can't follow your chronology.

 

What is your current withdrawal-related problem?

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

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On 9/26/2022 at 3:12 AM, Altostrata said:

 

I am utterly confused. Neither Vyvanse nor Effexor appear in your signature. I can't follow your chronology.

 

What is your current withdrawal-related problem?

I need to update my signature.

I don't think it is a withdrawal problem. I think the Effexor screwed me up right from the start. I started getting this vibration sensation when I started it and it has not got any better or worse since coming off it. 

Escitalopram: late 2016 - early 2017
Olanzapine 5mg: started for two months in 2017, discontinued and am currently taking again
Abilify 5mg: one week in late 2017
Valium: occassionally
Mirtazapine: 2017 with gradual increasing to 60mg - tapered off at 7.5mg every few weeks. Insomnia and zaps continuing
Temazepam: occasionally
Other meds taken for short periods (up to a few months): Seroquel, Sertaline, Fluoxetine, Fluvoxamine, Zyban, Valdoxan
July 2022: Effexor for a few weeks- 37.5mg. Vyvanse 15-30mg for a few days.

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  • Administrator

Do you mean the Effexor you took in July 2022? Were you taking Vyvanse at the same time? What other drug changes occurred in June and July?

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

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