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Weanie: Wellbutrin / bupropion


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Post moved from:  survivingwellbutrin: Wellbutrin withdrawal weight gain?


Hi , I’m new to this site and trying to figure out how and what to start tapering off of 1st. Currently on the highest dose Bupropion XL 450 mg 1x in morning.


Ive been on varied increasing doses of Wellbutrin /Bupropion since 1999. Tried tapering on my own in 2012 because I lost my insurance. It didn’t work to well and had to endure severe psychological & physical withdrawals for 3 months before I could get in to see the state provided psychologist. 


I’m really scared to taper and I’ve read the other meds my dr has me on have major drug interactions if taken together! Main one is high blood pressure and seizures. I’m over this roller coaster , my depression is controlled to some degree but still have persistent depression with other symptoms. I want to try to supplement with something natural and am about to drastically change my diet for the better . I want to be pill free ,healthy & happy !


Any suggestions or experiences welcome ...I’d also like to know how  “ survivingWellbutrin “ above is doing since your last post as weight gain is a concern of mine as well .

Thanks for letting me share 🤗 


Edited by ChessieCat
added note and spacing
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  • ChessieCat changed the title to Weanie: Wellbutrin / bupropion
  • Moderator

Hello, WEANie (nice name) and welcome to SA.


We need to know which drugs you are on and then we can make a recommendation about tapering.


To give members the best information, we ask them to summarize their medication history in a signature -- drugs, doses, dates, and discontinuations & reinstatements, in the last 12-24 months particularly.  Please put the answers to the above questions plus other requested information into your signature. 
  • Please use actual dates or approximate dates (mid-June, Late October) rather than relative time frames (last week, 3 months ago) 
  • Spell out months, e.g. "October" or "Oct."; 9/1/2016 can be interpreted as Jan. 9, 2016 or Sept. 1, 2016. 
  • Please leave out symptoms and diagnoses. 
  • A list is easier to understand than one or multiple paragraphs. 
  • Link to Account Settings – Create or Edit a signature 
At Surviving Antidepressants, it is recommended that a person taper by no more than 10% of their current dose with at least a four week hold in-between decreases.  The 10% taper recommendation is a harm reduction approach to going off psychiatric drugs.  Some people may have to taper at a more conservative rate as they are sensitive to even the smallest drops.  Please read the following links.
Before you begin tapering what you need to know
Why taper by 10% of my dosage?
Here is another informative link:
This is your introduction topic -- the place for you to ask questions, record symptoms, share your progress, and connect with other members of the SA community. I hope you'll find the information in the SA forums helpful for your situation. I'm sorry that you are in the position that you need the information, but I am glad that you found us.

Gridley Introduction


Lexapro 20 mg since 2004.  Begin Brassmonkey Slide Taper Jan. 2017.   

End 2017 year 1 of taper at 9.25mg 

End 2018 year 2 of taper at 4.1mg

End 2019 year 3 of taper at 1.0mg  

Oct. 30, 2020  Jump to zero from 0.025mg.  Current dose: 0.000mg

3 year, 10 month taper is 100% complete.


Ativan 1 mg to 1.875mg 1986-2020, two CT's and reinstatements

Nov. 2020, 7-week Ativan-Valium crossover to 18.75mg Valium

Feb. 2021, begin 10%/4 week taper of 18.75mg   

End 2021  year 1 of taper at 6mg

End 2022 year 2 of taper at 2.75mg 

Current dose as of Feb. 25, 2023 2mg

Taper is 89% complete.


Imipramine 75 mg daily since 1986.  Jan-Sept 2016 tapered to 16mg  

Held until Aug 2021, tapered for 4 weeks to 14.4mg

March 22, 2022: Begin 10%/4 week taper

Aug. 5, 2022: hold at 9.5 and shift to Valium taper

Taper is 87% complete.  


Supplements: omega-3, vitamins C, E and D3, magnesium glycinate, probiotic, zinc, melatonin .3mg

I am not a medical professional and this is not medical advice but simply information based on my own experience, as well as other members who have survived these drugs.

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