methuselah: Hi all! Brief intro and advice?

[ChessieCat]

I just wanted to remind you about this:

 

On 12/13/2021 at 8:08 AM, ChessieCat said:

And because of the long half life of Prozac any dose change you make could take up to 2 weeks, or sometimes more, to be noticed.

 

[Altostrata]

I would not take the powder directly. Either put it back into the capsule or take it in water or juice. See Tips for tapering off fluoxetine (Prozac)

[methuselah]

1 hour ago, Altostrata said:

I would not take the powder directly. Either put it back into the capsule or take it in water or juice. See Tips for tapering off fluoxetine (Prozac)

@Altostrata the capsules are too small to put the fluffy powder back into, it’s an impossible task.  I did order larger capsules and a capsule filling kit which I will have later today.  Unfortunately, again this morning, I just dumped the powder in my mouth and chase it down with water.  I can see how even breathing the wrong way with the powder in my mouth could drastically throw off the dose as the  powder could go anywhere including my lungs.  I assume that is the root of your concern?

 

11 hours ago, ChessieCat said:

I just wanted to remind you about this:

 

 

@ChessieCat  thanks for the info. I’ve seen a variety of info on here about 4 days for effect but I figured it would be a bit longer with the Prozac.  Based on that information, and the fact that I have a trip to NY scheduled for mid June, I am going to   make my dose decrease 5%, which I did this morning.  I know to keep it consistent, and I will keep it 5% going forward for at least 2 weeks.  This way. If I’m taking too much Prozac which is the working theory, that decrease may help too, but just a bit less.  If my symptoms are still from the previous dose change and the expired drug, etc etc, then this more conservative drop will have less of an impact in terms of further withdrawal.   My goal is to do an extremely conservative taper anyway.  I need to switch to liquid, but I don’t know when given all that keeps happening.  I guess after I stabilize on the 5% drop.  
 

@Altostrata@ChessieCatDo you think I should just go with the 10% drop as initially suggested or is 5% a reasonable first step.  

[Altostrata]

The powder could irritate your mouth, throat, or lungs.

[methuselah]

May 22

 

8am - Woke with anxiety for first time in a while, slept poorly last night, significant physical activity and big fight with gf again yesterday.  Anxiety remnants from last night no doubt, also nervous to drop dose.  Almost didn’t do it, but forced it and dropped the dose from 10 to 9 using crude measurement like cutting lines.  Gemini Scale ordered for tomorrow delivery.

 

830am 9 mg Prozac

 

930am - some irritability and agitation.

 

330 pm - Tired through 4 hour drive home from Asheville and kinda spaced out.  Some anxiety popped up and depression.  In a haze from yesterday, difficult to tell impact of dose decrease.

 

7pm - dinner, first actual meal of the day. Rest of day diet had been fruit, toast, and Clif bars type things. Windowish through rest of evening with a slight uncomfortable anxiety brimming under the surface.

 

12am - fell asleep.

 

*zero appetite all day, forced down about 1500 calories max, which prob isn’t enough.

 

 

May 23

 

6am - woke with some anxiety and DR.  Fell back to sleep

 

8am - woke.  Called off work, just couldn’t do it today.

 

830 am - 9.5 mg Prozac powder ingested and chased with water.  Going to create a 10ml 10mg 1mg/1ml water solution tomorrow morning and take 9.5ml.

 

10am - anxiety and some intrusive thoughts lingered through this time and lifted a bit when I finally got up and started moving a bit.  The absolute worst intrusive is the SI.  I have no desire to do anything like that, but that doesn’t stop the thiight from popping into my head.  It’s like the thought and the fear that I’ll do it and fear that I’ll be compelled to do it.  Feels like OCD.  It can be so intense, awful.  The literal worst symptom I’ve had to deal with.

 

1030am - anxiety 6/10.  Some chest tightness.  Perhaps I should have kept things at 9mg.  Tomorrow I’m going try a 10 ml solution and take 9ml.   More accurate and easier.  Going back to 9mg. Tired yesterday is better than anxious today.  Let’s see how rest of day goes.  Ate a banana and Cliff bar.  Zero appetite.

 

1130am - anxiety 1/10.  Windowish but some breakthrough anxiety, fear, dr, etc.

 

1230 pm - Shakey and sorta jittery. Lunch 2 eggs and 2 pieces whole wheat toast.  Food seems to help sometimes.

 

2pm - food seemed to help.  Jitters went away, must have been blood sugar.

 

5pm - super fatigued and super lazy all day.  Zerooo energy.  Could have something to do with the 8mile hike I took Saturday, probs so.  Coupled with the drop in Prozac, probably so.  Stood up and got dizzy which freaked me out A bit, of course it has happened before a thousand times. Also had a few mild jerks and ticks, myoclonic perhaps?

 

630 - had not eaten much and knew I was due to.  Got up to get some food and got very lightheaded, shakey, faint feeling, like hypoglycemia.  Ate a Cliff bar but had to sit for 20min.  And that seemed to help a bit.  Followed with dinner.  Still shakey. Went away over time.

 

Felt ok rest of night.  Sleep by 1am

 

“Me drugging myself is me running from myself”…elbee

[Altostrata]

Why did you decrease to 9mg and then take 9.5mg the next day? It will take at least a week or two to see the full effect of a change in Prozac dosage.

[methuselah]

@Altostrata the reason for the 9.5mg dose I wrote in quote below, and further, honestly, im pretty nervous about the whole thing.  I swear I’ve felt it already as I’ve been feeling sorta strange since the drop.  Some good strange and some bad strange.  Do you think I’m doing the wrong thing here?

 

On 5/23/2022 at 9:40 AM, methuselah said:

On 5/22/2022 at 10:06 PM, ChessieCat said:

I just wanted to remind you about this:

 

 

@ChessieCat  thanks for the info. I’ve seen a variety of info on here about 4 days for effect but I figured it would be a bit longer with the Prozac.  Based on that information, and the fact that I have a trip to NY scheduled for mid June, I am going to   make my dose decrease 5%, which I did this morning.  I know to keep it consistent, and I will keep it 5% going forward for at least 2 weeks.  This way. If I’m taking too much Prozac which is the working theory, that decrease may help too, but just a bit less.  If my symptoms are still from the previous dose change and the expired drug, etc etc, then this more conservative drop will have less of an impact in terms of further withdrawal.   My goal is to do an extremely conservative taper anyway.  I need to switch to liquid, but I don’t know when given all that keeps happening.  I guess after I stabilize on the 5% drop.  

 

[methuselah]

May 24

 

830am - Woke and took 9.5mg Prozac.  Had some racing thoughts, anxiety, etc. zero motivation for work but gotta do it.

 

1030am - very tired with no motivation or energy. Depressed with some intrusive thoughts.

 

1130am - ate lunch.  Cold and shivering, intense shivering.

 

130pm - cold/shivering slowed down.  Tired.  Brain fog.

 

5pm - couch bound.  No energy.  No motivation.

 

630pm- decent window for an hour or so.

 

Sort of  Ok the rest of the evening, sort of slight anxiety and intrusive thoughts simmering underneath, with some Sensitivity to violent/dark television, which is crazy because I’ve watched every horror movie worth watching.  May have to put that down for a bit it seems.

 

1am - sleep.

[methuselah]

May 26

 

8am - wake and take 9.5mg Prozac

 

930 am - got out of bed and worked.  Feel ok with some energy.

 

1130am - smoothie.

 

130pm - took a walk for 30 minutes, it was more difficult then it should have been.  Sorta felt weak and fatigued too quickly.

 

230-6pm - windowish.  Had some real feelings break through there a few times

, good actual feelings.  Unblunted.

 

630pm - few heart palps.  Some anxiety and DR while out at dinner, consistently happens when our at crowded places that are loud.   

 

830pm - dizziness, sorta brain buzzing, head heavy.  Had to lay down.

 

1230am - Sorta fine rest of night with some DR.  Sleep

[methuselah]

 

May 27

 

815am - wake and take 9.5 mg Prozac

 

11am - Ok through morning with some anxiety, some restlessness.  Food seemed to help.

 

215pm - head feels heavy, almost like it’s filled with sand or something.

 

4pm - hard wave of anxiety and weird/dark thinking, DR.  1800mg epa/dha fish oil

 

Rest of night was decent, binged stranger things. Could the fish oil have helped!?  Turns out i haven’t been taking nearly enough fish oil all these months, like a third to a half of what I should have been.  Gonna juice that fish oil dose up!!!

 

May 28

 

830am - 9.5mg Prozac

 

Morning was fine but significant stress event at noon set a horrible tone for the day - hopefully that stressor has been permanently removed from my ecosystem.  Based on the stressful event, I consider the rest of the day notes irrelevant as stress has major impact on symptoms.  Exhausted, racing thoughts, buzzing head, intrusive thoughts, etc.

 

*1800mg dha/epa

 

[methuselah]

@Altostrata it’s been about 3 weeks since my .5mg drop in Prozac.  Is it normal to be this depressed, in waves, from such a small drop in what is considered an “easier to taper” drug?  Admittedly, there was a pretty difficult breakup about 10 days ago and I’m really reeling from that.  She has moved on and I’m here, damaged.   Alll the medication issues since thanksgiving  effectively ruined the relationship. The depression just feels so exaggerated.  Jesus, it’s brutal.  Feeling sooooo alone.  This isn’t easy stuff.
 

Thanks for any thoughts. 

 

M

[Altostrata]

15 minutes ago, methuselah said:

Admittedly, there was a pretty difficult breakup about 10 days ago and I’m really reeling from that.  She has moved on and I’m here, damaged.

 

Pretty clear that situational influences have intervened. I would not attribute your feelings to your recent reduction.

[methuselah]

@Altostrata I’ve been through breakups before, and a divorce, this feels like an extremely amplified version of depression.  Maybe it’s not per the reduction, but the wave of depression hit today  after a strange auditory distortion, which I’ve only felt from an previous attempted failed taper.  I just feel very very sensitive to things and while my emotional state of being sad may be normal, it feels very very exaggerated.

[Altostrata]

Might be best for you to not taper for a good while until you get well past upsetting life events.

[Heath]

1 hour ago, methuselah said:

I just feel very very sensitive to things and while my emotional state of being sad may be normal, it feels very very exaggerated.

More sensitive to things is part of withdrawals and tapering and healing. 
 

for example food preservatives never bothered me. But sometimes during tapering it causes me to have headaches and feel tired. And sometimes my ears are more sensitive to sound not before. And in relationships I have found sometimes I can be more sensitive to what someone says to me. Where it didn’t bother me before. 
 

as alto said the waves of feelings you are having are most likely from the break up. And the tapering, remodeling brain healing can give us more sensitivity  to things.   Both being temporary.  Stressful situations are a good time to put taper on pause also temporary.

[methuselah]

@Altostrata@Heath  thanks for the feedback.  I literally just started the taper in may after a 6 month hold, where I never really stabilized, because alto was thinking I was reacting to too much of the drug.  It feels to me like I’m reacting to the drug (some paradoxical effext perhaps) and also hooked on it so I’m between a rock and a hard place here.  I’m really at a loss as I can’t go any direction including still without negative repercussions, tough spot.  

[Heath]

@methuselahCompletely understand. 

Is it allergy season where you are? I have weird ear /auditory feeling and sensations during wd, and tapering. The reason I thought of this is because I was just outside and I started feeling heavily fatigued, loopy, brain fatigue, dizzy feeling and exhausted. It hit me within in one hour. It alarmed me a little. And then I felt the pressure in my ears. Then I knew what it was. Allergies. Before taking  lexapro and having withdrawals and tapering slow I never had this much sensitivity to pollen . It has always been sneezing and watery eyes before ssris. 
 

speaking of the hold . I know 6 months is a long time. But there is no set time. Before - different times I have stabilized at 4 months and another time it was about 9 months. Stress can put us in a wave and prolong it a little longer. When life stresses come on Holding dosage is  the best thing to do in the drug department.  

[methuselah]

@Heath I’m in Raleigh, NC and allergy season has thankfully passed,  the massive amounts of pollen did seem to impact me more than normal this year so your definitely onto something.  
 

im pretty sure I’m experiencing neuro emotions.  I just had another read through the posts on that and that’s almost certainly what it is.  Exaggerated feelings of:

 

neuro-guilt

neuro-shame

neuro-hurt and deep sadness and loneliness

neuro-regret

neuro-self-criticism

Fortunately it comes in waves and doesn’t seem to be static, though this most recent bout of “neuro depression”, to use an all enompassing term, hit pretty hard and is stickier than usual.  
 

The only way out is through. 

[Heath]

Methuselah yes. 
spring is tree pollen 

summer is grass pollen 

fall is weed pollen

here in south east USA 

 

I have allergies to all 3 🙄. So I get one clear headed season 🤪. 
 

and yes neuro emotions. Just about all wd suffers experience this at one time or another. And it does come and go. 
It takes time to learn what’s causing what when we are taking these drugs or are in wd. Once you begin to see what it is it makes it easier. But even though it is easier and we acknowledge it could be wd - it still isn’t always crystal clear on cause. 
 

you get caught in a loop and they all feed off each other. It’s hard to break the cycle sometimes. 
 

I don’t get neuro emotions much anymore after finding  SA and practicing. Acknowledge accept and float. But some every now and then. The more experience I get and what I have learned it gets easier to catch and head it off with self help. They are all bad but I really hate the guilt one. 
 

there is a lot of info about it on SA. I’m glad you have read and acknowledge it. 

[methuselah]

@Altostrata @brassmonkey @ChessieCat

@Onmyway
 

Hi all,  sorry to ping you all but I’m having a bit of an emergency.  I’m working on transitioning from brand name Prozac water solution to compounding pharmacy liquid.  I’m currently at 9.2mg Prozac daily.  My transition so far has been brand name water solution of 7 mg and compounding liquid of 2.2mg….did This for four days no real issues other than a little out of it at times.  Today is day two of 5mg brand name water solution and 4.2mg compounding liquid and I’m getting some kind of negative reaction today.  I took the drugs at 830 am, and started to get anxious at about 1030 followed by just laying here in bed shivering a lot, full body shaking like muscles contracting sort of, with some ectopic heart stuff.  I’m clearly having some kind of reaction to something here.  

so, Do I slow down the transition or abort it entirely or what bc I cannot function like this?  I’m thinking maybe go back to first phase of transition, 7mg brand and 2.2mg compound and sit there for a week or so then slow way down on transition like 1mg changes per week or two weeks. Thanks so much for feedback and thoughts!!!

 

edit - no other changes or additional or new supplements or anything like that. No missed days, no taking anything late or anything like that. Stress has been high last few days but this is definitely abnormal and feels pretty clearly like a reaction to the change in making.

 

[Onmyway]

@methuselah, so sorry you may be having a reaction to the new drug formulation.

I can't think why that is. I wonder if there is a different ingredient in the drug to which you are reacting but if so I would think you would be reacting the first time you took it.

 

Another option is that there is some variation in the bioavailability. Some small variation in generics is allowed and it is small enough that it wouldn't normally matter but in people like us with sensitized systems it might. If the bioavailability of the new version is less it shouldn't feel like a huge drop to you yet because prozac has such a long half life that you still have drug in your system from a month ago. However, if the bioavailability is higher then it might hit you faster. I am not sure what is going on (I am not a pharmacist or a doctor). Safest bet seems to be to go back to your old drug. Did you change because of cost issues?

 

If you have insurance they will usually make you change to generic to save money but you can have your doctor write 'no substitution' on the prescription and insist on the prozac brand. They have to honor that. It will likely be more expensive but you can argue with the insurance company that you need this one and shouldn't pay more (not sure if it will be successful and not sure if that is even an issue for you). 

Edited July 27, 2022 by Onmyway

[methuselah]

Thanks for chiming in @Onmyway.  The generic is from a compounding pharmacy and according to the pharmacist there, it’s basically just the fluoxetine molecule mixed in a suspension.  I’m switching as it is cheaper and also I was getting some nasty dizziness, blurred vision, etc from my ultra slow taper on the brand name water solution I make which may be I incorrectly attributed to the brand name changing something. Up.  I’m basically lost at this point and clueless, feel that way far too often these days. 
 

Also worth noting is that I’m highly sensitive so I very well may be just changing over drugs way too fast.  Thought I’d sort of go for it but I should have known better.  I also prob understated the amount of stress I dealt with in the last few days which definitely isn’t helping anything.  

[brassmonkey]

It is not uncommon for people to have problems like this switching from brand name to generic. It is usually claimed that they are identical, but they are not. I suspect that this is the problem. You could try slowing down the cross-taper and see what happens, but I have a feeling it won't help.

 

The two different suspension mediums could also be adding to the problem. They would have different absorption rates and the like. It could be possible to get use to the new medium, but it would probably cause several months of discomfort while your body adjusts. There is also a possibility of symptom buildup that leads to a crash, which you don't want to happen.

 

I would reverse taper back to your previous 7/2.2 for a couple of weeks and then back to all original and stabilize there.

[methuselah]

@brassmonkey

 

@Onmyway

 

thanks both for chiming in.  I’m currently dumping the Prozac capsule into water and using that solution for the brand name drug delivery.  The compounding pharmacy has the fluoxetine suspended in unispend - ORAL SUSPENDING VEHICLE UniSpend Anhydrous® Unsweetened is an elegant, easy to use, anhydrous plant-based oral suspension vehicle. This product utilizes medium chain triglycerides that are resistant to oxidation and preservative-free.

 

the problem with the brand name is that it’s 500 per month until I reach my deductible, then it’s 70$ per month.  It also requires annual pre authorization for them to even allow the money spent to go to my deductible so using it is a burden.  
 

ideally I’d like to try to switch over to the compound as it’s cheaper, more accurate dosage, easier to taper, etc.  also, I started the brand name about 7 months ago after some issue with an expired or bad batch of generic and haven’t ever really felt well on the brand name anyway. Recently I’d been getting some bad dizziness which coincidentally has mostly gone away since starting to move over to the compound.

 I’m thinking of maybe stepping back to the previous 7.2/2 for a week or so and then trying again but at a much slower pace with hopes of being fully transitioned over in a few months.  maybe switch out like .5mg per week or two, something like that. You think this approach is flawed and I should just stick with the brand and hope the dizziness and blurred vision doesn’t come back?

[brassmonkey]

I can understand the financial reasons for wanting to change, the big question is whether your body will let you. It's worth a shot to updose a bit, hold until good and stable and then try again at a slower rate. I would go with at least two or three weeks between reductions when you resume.

[Altostrata]

Is this compounded liquid less expensive than the generic prescription liquid?

[methuselah]

No, it costs a bit more than the generic liquid but it’s supposedly cleaner and more consistent in its dosing and is only the fluoxetine molecule plus the suspension, no alcohol, no offshore massive manufacturing factory with unknown quality control practices, etc.  maybe it’s exactly the same thing and I’m just being sold a bill of goods. 

[Altostrata]

On 7/27/2022 at 8:18 AM, methuselah said:

My transition so far has been brand name water solution of 7 mg and compounding liquid of 2.2mg….did This for four days no real issues other than a little out of it at times.

 

Fluoxetine has a longer half-life than other antidepressants. The liquid, which is based on a generic, may be slightly stronger than your name-brand Prozac. Four days was too short a period to adapt to a change. When you increased the compounded liquid component, you might be slightly overdosing, with effect increasing as fluoxetine ramps up over weeks.

 

Suggest you go back to 7mg homemade suspension with 2.2mg compounded liquid for a week, then change to 5mg homemade with 4mg  compounded for 2 weeks. This is a slight reduction in overall daily fluoxetine dose.

 

If this seems okay, then 3mg homemade with 6mg compounded for 2 weeks, then 9mg compounded. Please let us know how you're doing.

[methuselah]

Hi @Altostrata, thanks for the feedback and support as always.  
 

I’m definitely feeling strange today with some irritability, anxiousness, and just feeling odd and off.  Stress never helps and I’ve had plenty of that as well.  I may just abort the whole thing and just deal with the cost and keep making the homemade solution.  I’m so worn out it’s tough to push through another change again and not know what’s happening again with underdosimg, overdosing, etc etc.  so if I wanted to abort entirely, can I just go back to the 9.2 homemade solution and call it a day?

 

Or, if I wanted to walk this back and try it much slower, could I go back to say 8.5 homemade solution and .7mg compound tomorrow, hold that for a while than transition much slower keeping in mind  the strength difference in the generic liquid and shave off the .2 over a few weeks?  I’m clearly highly sensitive and this change it seems is just beginning to materialize and it’s getting uncomfortable at times. It started out so well too, 

[Altostrata]

Yes, you could do any of those.

[methuselah]

@brassmonkey @Altostrata

 

Thanks to both of you for chiming in on this and for the help, just wanted to give a quick update.  While there has been a significant amount of relationship stress lately that has significantly muddied the waters regarding what's causing what symptoms during the attempt to change over to the compounding liquid, i've become exceedingly uncomfortable as time has passed.  New symptoms like being agitated, almost sped up, STRONG anxiety like symptoms, burning skin, tinnitus, etc.  I'm taking Brass's original advice and aborted the attempt to cross taper today.  i just do not have the wherewithal to power through it with no guarantee it's actually going to workout and not continue to get worse.  I'm back to 9.2 prozac brand water solution as of this morning. 

 

What drove me to make to attempt the switch to the compound wasn't only cost and insurance nonsense, though that is a big factor, but some serious debilitating dizziness and blurred vision that came out of nowhere.  I was looking for a quick fix, again, from my problems with these drugs.  And while the dizziness did go away after starting the switch to compound, it's impossible to say that it went away because of the change, hell, maybe i just had some kind of ear infection as i fell asleep with airpods in a few nights in a row and my ears actually did hurt a bit.  Bottom line is, even if this dizziness does come back, i know that it will fade as i lower my prozac dose over time.  I need to work on my acceptance, which is quite a challenge.  Thanks again folks.

 

Matt

[methuselah]

Other new symptoms that showed up during crossover include exercise intolerance, exhaustion, strong hypoglycemic feeling, some clumsiness and lack of coordination. 

[methuselah]

@brassmonkey Hello sir!  I really do hate to bother you but I am need of your expertise yet again.  
 

The recent failure of my switch to the compound aside, I’ve never really been able to hone in on what exactly is happening in my particular situation, and poop out aka tachyphylaxis seem to ring the most true to me based on my reading of the site.  My gut feeling has always been that my body is both rejecting and needing the Prozac at the same time.  I held for 6 months after a 2mg drop and switch to brand name after a few different issues that occurred in December 2021 (bad or expired generic batch leading to a crash of sorts), but never stabilized and in fact may have gotten worse the longer I held.  Some new symptoms crept in as well which never quite left (bouts of strong Depression, strong DR and anxiety, anhedonia) but seem to get somewhat better with the slight  taper down, but some new symptoms show up with the taper so that’s confusing.  
 

Ever since the December 2021 crash, everything has just been off and I’m trying to determine if I’m dealing with poop out or not and how to best handle it.  So, how do I figure out if I’m indeed in poop out? Thanks for any time U can spare!

PS - if it is poop out, it doesn’t seem like the Brassmonkey slide is appropriate for Prozac, so I’m at a bit of a loss on best tapering method as I seem pretty sensitive to everything at this point. I started a taper in late May and have dropped by .8 mg so far with mixed results as mentioned above.   
 

Matt

[brassmonkey]

Poopout is a funny condition that is hard to diagnose as the symptoms are so like all the other symptoms we get for tapering, destabilization, and the like. What you describe could be poopout or it could be destabilization from all the different drugs and changes you have used/made of the past several years. Either way the only way to reduce the symptoms is to reduce the drug. If you truly are experiencing poopout, then you will have to reduce slowly and for quite some time before you see any real improvements. If it is destabilization, you may see things improve fairly quickly.

 

The Brassmonkey Slide Method is designed to minimize the symptoms you feel while tapering. If you were to make 10% reductions all at once, it is quite possible that you will experience a strong spike in symptoms with each reduction. Because of your current destabilization it would more than likely take them a long time to resolve before you can reduce again. So yes, the Brassmonkey Slide would be a good way to go.

[rmce72a]

I am in a similar situation. I am tapering from poop out too but can't seem to stabilize even though I have been holding for 7 weeks at 73mg Effexor XR down from 75 mg.  My symptoms vary so from day to day. One day is ok, then the next is bad with heightened anxiety, loud tinnitus, dizziness, headache even though I don't change a thing. A few days ago, Alto told me I should continue holding, which is what I am doing. I wonder if I will ever be able to get off this drug. I hope you are able to find your way and heal, Methuselah.

[Altostrata]

On 8/2/2022 at 7:58 PM, methuselah said:

I’ve never really been able to hone in on what exactly is happening in my particular situation, and poop out aka tachyphylaxis seem to ring the most true to me based on my reading of the site.  My gut feeling has always been that my body is both rejecting and needing the Prozac at the same time.

 

From 2015 onward, you've had serial drug changes, one after another. You've been up and down with Prozac many times.

 

It's impossible to identify "poop-out" when there are so many drug changes. "Poop-out" occurs when someone has been taking a drug consistently and it stops having the effect it did. You are overthinking "poop-out".

 

On 5/20/2022 at 8:43 PM, methuselah said:

@Altostrata thanks.  I have made no drug changes since December 4, 202I.....

 

Please note that you started making changes in Prozac 5 months later.

 

On 5/21/2022 at 2:48 PM, Altostrata said:

This pattern indicates that 10mg Prozac may be causing the symptoms as it is absorbed. It's very possible this is too high a dose for you. You might try a 10% reduction, keeping daily notes to see how your symptom pattern changes.

 

Would be helpful to see those notes!