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LarryS: tapering off venlafaxine / Effexor 225mg


LarryS

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So glad to see your post, Larry. I am so glad to hear you are Covid negative and your WD is progressing. Take care

Prozac 10mg 1990-1999                 -1999-2018 Effexor XR 75 mg capsules

-2018 Dr direct switched me from Effexor 75XR to Cymbalta 20mg XR and 20 mg Metoprolol following irregular heartbeat incident  -Late 2019 began worsening anxiety/ depression symptoms     -2020 Dr direct switched  back to 75 mg Effex XR   Symptoms worsened   -2021 Changed Dr and began therapy for GAD and  Worsening physical symptoms   -2022 Found this forum and began slow taper by removing beads -    6/7 - 6/10 Effexor 73.2mg  6/11-6/14  Effexor 72.9mg   nightmares, tinnitus, anxiety;  6/15- Effexor XR 72.6mg  6/16 - 6/20 Effexor XR 72.8   nausea, heart palpitations, anxiety, tinnitus 6/22-7/4 hold Effexor XR 72.9-73.1     7/5-7/11  Effexor XR 72.62  7/12 - 7/15  Effexor 72.6  bad symptoms 

7/16-7/17 Effexor XR upped to 72.9  7/18 Effexor XR 72.9  most symptoms gone  hold at 72.9 - 73.0   8/26 - 9/6  Trying to keep dosage under 73. Holding around 72.9 sometime 72.86 due to bead count  Having symptoms most days.

9/6-9/23    Holding at about 72.9-73. Still very ill. No improvement.

9/23 - 11/23  Still keeping dose around 72.9-73

11-23-Jan 14   Held until one week ago. Dropped to 72.75-72.81  terrible WD

1/14- present   Worse WD symptoms. Back to 73.10. Cannot seem to stabilize.

2/2 - present Holding at about 73 hoping to stabilize

1/24 Updose to 73-73.2. Take only Clarinex 5mg for allergies and the Effexor 73 XR. I cannot take any supplements. No caffeine, sugar, soy, gluten, dairy.

3/19 - present Dropped to the 92.9's (vary from day to day._ Will drop too 72.89 in a week then hold for 304 weeks.

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  • Mentor

@LarryS I was pleased to see your post. Sorry to hear about the Covid in regard to both you and your wife but glad you both tested negative.

 

I am glad the tapering is going so smoothly for you.

 

Thanks again for posting.

 

I am not a health professional in any way.  I do not give medical advice.   Discuss any decisions about your medical care with a professional medical practitioner.

 

NEW INFORMATION FOR GABAPENTIN TAPER

April 29, 2022 900 mg to 800 mg (11%), May 29, 2022 800 to 700 mg (12.5%), June 20, 2022 700 to 650mg (8%), July 20, 2022 650 to 575 (12%), August 20,  575 to 500 (13%),  Sept 20, 2020 500 to 475mg (5%) Nov 7, 2022 475 to 425 (11%), Nov 21, 2022 500mg

Medications and supplements: Gabapentin, Prednisone 4mg a day, Cortisol Inhaler daily,  Fish oil, vitamin D, Calcium

HISTORY FOR ZOLOFT TAPER

Feb. 2016 to June 2016  - Was on 150mg Zoloft.  Put on Gabapentin at 900mg a day in 2016 due to antidepressant withdrawal. 

Quit Zoloft (Sertraline) June  2016,  reinstated 50mg of Zoloft July 2016.  From July 2016  to October 2016 went from 50 mg down 2.3 mg. I up-dosed in November 2016 to 12.5 mg. Held there until January 2017 when I started a much slower taper.

STARTING SENSIBLE  ZOLOFT TAPERING USING GUIDELINES FROM THIS SITE

Dec. 10 2016  - switched to Liquid Zoloft (Sertraline) @ 12.5 mg.   Jan. 4, 2020 1.875 mg (6.3%). Jan. 25, 2020 1.75 mgFeb. 29, 2020 1.625mg (7.10%).  Apr. 4, 2020 1.5 mg.  May 9, 2020 1.375 mg.  June 6, 2020 1.25 mg. (9.10%).  July 4, 2020 1.125 mg. (10%).  August 15, 2020 1.0 mg.  Oct 24, 2020 .875 mg.  Nov. 28, 2020 .75mgJan 16, 2021 .685mg (8.7%).  Feb 13, 2021 .62mg. March 12, 2021 .56mg.  May 1, 2021 .375mg.  May 29, 2021 .25mg. June 26, 2021 .0125mg. July 25, 2021 .065mg. August 22, 2021 .048mg.  October 2, 2021 .043mg.  October 10, 2021 .038mg.  October 23, 2021 .035mg.  October 30, 2021 .032mg.  Nov. 13, 2021 .030 mg.  Dec 4, 2021 .0285 mg.  Dec 11, 2021 .0265 mg. Dec 18, 2021 .0246 mg. Dec 25, 2021 .023mg. Jan 1, 2022. 0 mg. OFF COMPLETELY

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  • 1 month later...

Five Week Hold: 20% Drop From 1.88 mg


Dropping to 1.50 mg February 9, 2023.  To do this drop, I am cutting from 5 beads to 4 beads, each bead valued at 0.375 mg.  

 

Tapering over the past five weeks has gone smoothly.  Back pain and neck pain have been constant and significant.  Neck pain has been accompanied by what I will call cognitive fog quite often lately.  Performing basic tasks becomes more difficult when I experience cognitive fog.  I can obtain some short-term relief by icing, hot bath and massage.

 

I turn 75 years old this February.  I continue to provide caregiving to my wife who has vascular dementia.  

 

Scores below are the average over the past 35 days of the drop period.  

Anhedonia      3.00    Feeling caring about myself and others with some motivation.

Insomnia         2.62    Slept minimum 7 hours with 2+ interruptions during the night.

Fatigue            4.11    Mild to moderate fatigue all day.

Head-pressure    1.37    No headache or odd feelings in my head.  Clear head.

Back Pain        7.08    Uncomfortable pain.

Neck Pain       6.51    Uncomfortable pain.

 

I consider a score of 7 and above getting into the hard to tolerate range.

Scores in all categories have moderately increased since the previous tapering period.  The overall score is below my previous highest overall score.
 

See LarryS Health History, Introduction's page 6, 4th post from top.

Aug 2014 start Venlafaxine 225 mg.

Other Pharmaceuticals per day:  Amlodipine Besylate 5 mg, As need Melatonin 3 mg

Vitamins per day:  C 1,000 mg; D3 50 mcg; Probiotic 218 mg; Fish Oil 1,600 mg; Magnesium Glycinate 240 mg; CoQ10 40 mg; Saw Palmetto 320 mg; Calcium 250 mg; Red Yeast Rice 1,200 mg; Plant Sterol Esters 1,000 mg

Start Taper: 225 mg to 55 mg; June 5, 2018, to June 15, 2019

49 mg July 16, 2019; 44 mg August 13, 2019; 49 mg (up 11%) Aug. 26, 2019: 44 mg Sept. 10, 2019; 40 mg Oct. 8, 2019;  37.5 mg (6%) Nov. 6, 2019; 49.5 mg (up 32%) Nov 18, 2019; 44.5 mg Dec. 30, 2019; 40 mg Jan. 27, 2020; 36 mg Feb. 24, 2020; 32.5 mg March 23, 2020; 29.2 mg April 20, 2020; 26.3 mg May 18, 2020; 23.7 mg June 15, 2020; 21.3 mg July 6, 2020; 19.2 mg Aug. 4, 2020; 17.3 mg Sept. 1, 2020; 15.5 mg Sept. 29, 2020; 14.0 mg Oct. 27, 2020; 12.6 mg Nov. 24, 2020; 11.3 mg Dec. 15, 2020; 10.2 mg Jan. 5, 2021; 9.2 mg Feb. 2, 2021; 8.3 mg March 9, 2021; 7.4 mg April 6, 2021; 6.7 mg 5/4/2021; 6.0 mg 6/01/2021; 5.4 mg 7/13/2021; 4.9 mg 8/10/2021; 4.4 mg 9/9/2021; 4.0 mg 10/14/2021; 3.5 mg 11/11/2021; 7.5 mg (up 200%) 12/6/2021; 6.75 mg 1/17/2022; 6.00 mg 2/21/2022; 5.62 mg 3/21/2022; 4.87 mg 4/25/2022; 4.50 mg 5/30/2022; 4.13 mg 7/5/2022; 3.75 mg 8/1/2022; 3.38 mg 9/7/2022; 3.00 mg 10/5/2022; 2.63 mg 11/02/2022; 2.25 mg 12/1/2022; 1.88 mg 1/5/2023; 1.50 mg 2/9/2023; 1.13 mg 3/16/2023;

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Hello Larry. I am so happy that you are able to continue your taper and that it is so far, so good. I am down from 75 XR to 73 XR in 8 months.

 

Saw my doc today who told me that even though he has supported me in the slow taper/bead counting, he is very worried about overall health. I, too, am 75 years old and have lost 25% of my body weight in 9 months due to food and supplement intolerance. He says I look anorexic, and if this continues, I will not last a year as other body systems/organs are starting to suffer due to inadequate nutrition and my constant high anxiety. I have refused everything he has suggested for 2 years (bridge drugs, changing AD, fast taper, etc.), because I want to follow the safe protocols and guidance here and not de-stabilize my CNS more. 

 

I just don't know what to do and where to turn. I know I am growing weaker...I can feel it. But I want to heal my CNS and get off this drug safely. I knew none of this would be easy, but I did not think it could kill me. What do you think?

Prozac 10mg 1990-1999                 -1999-2018 Effexor XR 75 mg capsules

-2018 Dr direct switched me from Effexor 75XR to Cymbalta 20mg XR and 20 mg Metoprolol following irregular heartbeat incident  -Late 2019 began worsening anxiety/ depression symptoms     -2020 Dr direct switched  back to 75 mg Effex XR   Symptoms worsened   -2021 Changed Dr and began therapy for GAD and  Worsening physical symptoms   -2022 Found this forum and began slow taper by removing beads -    6/7 - 6/10 Effexor 73.2mg  6/11-6/14  Effexor 72.9mg   nightmares, tinnitus, anxiety;  6/15- Effexor XR 72.6mg  6/16 - 6/20 Effexor XR 72.8   nausea, heart palpitations, anxiety, tinnitus 6/22-7/4 hold Effexor XR 72.9-73.1     7/5-7/11  Effexor XR 72.62  7/12 - 7/15  Effexor 72.6  bad symptoms 

7/16-7/17 Effexor XR upped to 72.9  7/18 Effexor XR 72.9  most symptoms gone  hold at 72.9 - 73.0   8/26 - 9/6  Trying to keep dosage under 73. Holding around 72.9 sometime 72.86 due to bead count  Having symptoms most days.

9/6-9/23    Holding at about 72.9-73. Still very ill. No improvement.

9/23 - 11/23  Still keeping dose around 72.9-73

11-23-Jan 14   Held until one week ago. Dropped to 72.75-72.81  terrible WD

1/14- present   Worse WD symptoms. Back to 73.10. Cannot seem to stabilize.

2/2 - present Holding at about 73 hoping to stabilize

1/24 Updose to 73-73.2. Take only Clarinex 5mg for allergies and the Effexor 73 XR. I cannot take any supplements. No caffeine, sugar, soy, gluten, dairy.

3/19 - present Dropped to the 92.9's (vary from day to day._ Will drop too 72.89 in a week then hold for 304 weeks.

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@rmce72a  Based upon what you are telling me, your health is very concerning.  All I can recommend is that you continue to seek professional help. 

 

I read all of your page 7 blog.  

 

@FindRest  Relates well with you and I like his advice for you.

See LarryS Health History, Introduction's page 6, 4th post from top.

Aug 2014 start Venlafaxine 225 mg.

Other Pharmaceuticals per day:  Amlodipine Besylate 5 mg, As need Melatonin 3 mg

Vitamins per day:  C 1,000 mg; D3 50 mcg; Probiotic 218 mg; Fish Oil 1,600 mg; Magnesium Glycinate 240 mg; CoQ10 40 mg; Saw Palmetto 320 mg; Calcium 250 mg; Red Yeast Rice 1,200 mg; Plant Sterol Esters 1,000 mg

Start Taper: 225 mg to 55 mg; June 5, 2018, to June 15, 2019

49 mg July 16, 2019; 44 mg August 13, 2019; 49 mg (up 11%) Aug. 26, 2019: 44 mg Sept. 10, 2019; 40 mg Oct. 8, 2019;  37.5 mg (6%) Nov. 6, 2019; 49.5 mg (up 32%) Nov 18, 2019; 44.5 mg Dec. 30, 2019; 40 mg Jan. 27, 2020; 36 mg Feb. 24, 2020; 32.5 mg March 23, 2020; 29.2 mg April 20, 2020; 26.3 mg May 18, 2020; 23.7 mg June 15, 2020; 21.3 mg July 6, 2020; 19.2 mg Aug. 4, 2020; 17.3 mg Sept. 1, 2020; 15.5 mg Sept. 29, 2020; 14.0 mg Oct. 27, 2020; 12.6 mg Nov. 24, 2020; 11.3 mg Dec. 15, 2020; 10.2 mg Jan. 5, 2021; 9.2 mg Feb. 2, 2021; 8.3 mg March 9, 2021; 7.4 mg April 6, 2021; 6.7 mg 5/4/2021; 6.0 mg 6/01/2021; 5.4 mg 7/13/2021; 4.9 mg 8/10/2021; 4.4 mg 9/9/2021; 4.0 mg 10/14/2021; 3.5 mg 11/11/2021; 7.5 mg (up 200%) 12/6/2021; 6.75 mg 1/17/2022; 6.00 mg 2/21/2022; 5.62 mg 3/21/2022; 4.87 mg 4/25/2022; 4.50 mg 5/30/2022; 4.13 mg 7/5/2022; 3.75 mg 8/1/2022; 3.38 mg 9/7/2022; 3.00 mg 10/5/2022; 2.63 mg 11/02/2022; 2.25 mg 12/1/2022; 1.88 mg 1/5/2023; 1.50 mg 2/9/2023; 1.13 mg 3/16/2023;

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Thank you so much.

Prozac 10mg 1990-1999                 -1999-2018 Effexor XR 75 mg capsules

-2018 Dr direct switched me from Effexor 75XR to Cymbalta 20mg XR and 20 mg Metoprolol following irregular heartbeat incident  -Late 2019 began worsening anxiety/ depression symptoms     -2020 Dr direct switched  back to 75 mg Effex XR   Symptoms worsened   -2021 Changed Dr and began therapy for GAD and  Worsening physical symptoms   -2022 Found this forum and began slow taper by removing beads -    6/7 - 6/10 Effexor 73.2mg  6/11-6/14  Effexor 72.9mg   nightmares, tinnitus, anxiety;  6/15- Effexor XR 72.6mg  6/16 - 6/20 Effexor XR 72.8   nausea, heart palpitations, anxiety, tinnitus 6/22-7/4 hold Effexor XR 72.9-73.1     7/5-7/11  Effexor XR 72.62  7/12 - 7/15  Effexor 72.6  bad symptoms 

7/16-7/17 Effexor XR upped to 72.9  7/18 Effexor XR 72.9  most symptoms gone  hold at 72.9 - 73.0   8/26 - 9/6  Trying to keep dosage under 73. Holding around 72.9 sometime 72.86 due to bead count  Having symptoms most days.

9/6-9/23    Holding at about 72.9-73. Still very ill. No improvement.

9/23 - 11/23  Still keeping dose around 72.9-73

11-23-Jan 14   Held until one week ago. Dropped to 72.75-72.81  terrible WD

1/14- present   Worse WD symptoms. Back to 73.10. Cannot seem to stabilize.

2/2 - present Holding at about 73 hoping to stabilize

1/24 Updose to 73-73.2. Take only Clarinex 5mg for allergies and the Effexor 73 XR. I cannot take any supplements. No caffeine, sugar, soy, gluten, dairy.

3/19 - present Dropped to the 92.9's (vary from day to day._ Will drop too 72.89 in a week then hold for 304 weeks.

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  • 1 month later...

Five Week Hold: 25% Drop From 1.50 mg

 

Dropping to 1.13 mg March 16, 2023.  To do this drop, I am cutting from 4 beads to 3 beads, each bead valued at 0.375 mg.  

 

Tapering over the past five weeks has gone smoothly.  

 

Back pain and neck pain have been constant and significant.  Sometimes my neck pain is accompanied by feeling like I am in a cognitive fog.  Occasionally I have also experienced balance instability.  I consulted with the doctor, that has given me pain relief shots in my low back previously, yesterday.  I discussed my neck pain issues.  My first step is to get an updated MRI of my neck today.

 

Scores below are the average over the past 35 days of the drop period.  
Anhedonia      3.00    Feeling caring about myself and others with some motivation.

Insomnia         3.14    Slept minimum 6 hours with 1 interruption during the night.

Fatigue           3.02    Minor fatigue after noon.

Head-pressure    1.00    No headache or odd feelings in my head.  Clear head.

Back Pain       6.57    Uncomfortable pain.

Neck Pain      6.42    Uncomfortable pain.

 

I consider a score of 7 and above getting into the hard to tolerate range.  I scored 19 days with back pain of 7 during this last period.  I scored 12 days with neck pain of 7 or above during this last period.  The average scores above for both back and neck pain slightly decreased from the previous period scores.
 

See LarryS Health History, Introduction's page 6, 4th post from top.

Aug 2014 start Venlafaxine 225 mg.

Other Pharmaceuticals per day:  Amlodipine Besylate 5 mg, As need Melatonin 3 mg

Vitamins per day:  C 1,000 mg; D3 50 mcg; Probiotic 218 mg; Fish Oil 1,600 mg; Magnesium Glycinate 240 mg; CoQ10 40 mg; Saw Palmetto 320 mg; Calcium 250 mg; Red Yeast Rice 1,200 mg; Plant Sterol Esters 1,000 mg

Start Taper: 225 mg to 55 mg; June 5, 2018, to June 15, 2019

49 mg July 16, 2019; 44 mg August 13, 2019; 49 mg (up 11%) Aug. 26, 2019: 44 mg Sept. 10, 2019; 40 mg Oct. 8, 2019;  37.5 mg (6%) Nov. 6, 2019; 49.5 mg (up 32%) Nov 18, 2019; 44.5 mg Dec. 30, 2019; 40 mg Jan. 27, 2020; 36 mg Feb. 24, 2020; 32.5 mg March 23, 2020; 29.2 mg April 20, 2020; 26.3 mg May 18, 2020; 23.7 mg June 15, 2020; 21.3 mg July 6, 2020; 19.2 mg Aug. 4, 2020; 17.3 mg Sept. 1, 2020; 15.5 mg Sept. 29, 2020; 14.0 mg Oct. 27, 2020; 12.6 mg Nov. 24, 2020; 11.3 mg Dec. 15, 2020; 10.2 mg Jan. 5, 2021; 9.2 mg Feb. 2, 2021; 8.3 mg March 9, 2021; 7.4 mg April 6, 2021; 6.7 mg 5/4/2021; 6.0 mg 6/01/2021; 5.4 mg 7/13/2021; 4.9 mg 8/10/2021; 4.4 mg 9/9/2021; 4.0 mg 10/14/2021; 3.5 mg 11/11/2021; 7.5 mg (up 200%) 12/6/2021; 6.75 mg 1/17/2022; 6.00 mg 2/21/2022; 5.62 mg 3/21/2022; 4.87 mg 4/25/2022; 4.50 mg 5/30/2022; 4.13 mg 7/5/2022; 3.75 mg 8/1/2022; 3.38 mg 9/7/2022; 3.00 mg 10/5/2022; 2.63 mg 11/02/2022; 2.25 mg 12/1/2022; 1.88 mg 1/5/2023; 1.50 mg 2/9/2023; 1.13 mg 3/16/2023;

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  • Mentor
Posted (edited)

@LarryS I dropped by to wish you good luck with your most recent taper.  You seem to be doing well. I do wish your neck and back pain was lower, as do you. 

 

You had so much going on medically last year, I am pleased that you have recovered.

 

Stay well.

Edited by RachelSusan

 

I am not a health professional in any way.  I do not give medical advice.   Discuss any decisions about your medical care with a professional medical practitioner.

 

NEW INFORMATION FOR GABAPENTIN TAPER

April 29, 2022 900 mg to 800 mg (11%), May 29, 2022 800 to 700 mg (12.5%), June 20, 2022 700 to 650mg (8%), July 20, 2022 650 to 575 (12%), August 20,  575 to 500 (13%),  Sept 20, 2020 500 to 475mg (5%) Nov 7, 2022 475 to 425 (11%), Nov 21, 2022 500mg

Medications and supplements: Gabapentin, Prednisone 4mg a day, Cortisol Inhaler daily,  Fish oil, vitamin D, Calcium

HISTORY FOR ZOLOFT TAPER

Feb. 2016 to June 2016  - Was on 150mg Zoloft.  Put on Gabapentin at 900mg a day in 2016 due to antidepressant withdrawal. 

Quit Zoloft (Sertraline) June  2016,  reinstated 50mg of Zoloft July 2016.  From July 2016  to October 2016 went from 50 mg down 2.3 mg. I up-dosed in November 2016 to 12.5 mg. Held there until January 2017 when I started a much slower taper.

STARTING SENSIBLE  ZOLOFT TAPERING USING GUIDELINES FROM THIS SITE

Dec. 10 2016  - switched to Liquid Zoloft (Sertraline) @ 12.5 mg.   Jan. 4, 2020 1.875 mg (6.3%). Jan. 25, 2020 1.75 mgFeb. 29, 2020 1.625mg (7.10%).  Apr. 4, 2020 1.5 mg.  May 9, 2020 1.375 mg.  June 6, 2020 1.25 mg. (9.10%).  July 4, 2020 1.125 mg. (10%).  August 15, 2020 1.0 mg.  Oct 24, 2020 .875 mg.  Nov. 28, 2020 .75mgJan 16, 2021 .685mg (8.7%).  Feb 13, 2021 .62mg. March 12, 2021 .56mg.  May 1, 2021 .375mg.  May 29, 2021 .25mg. June 26, 2021 .0125mg. July 25, 2021 .065mg. August 22, 2021 .048mg.  October 2, 2021 .043mg.  October 10, 2021 .038mg.  October 23, 2021 .035mg.  October 30, 2021 .032mg.  Nov. 13, 2021 .030 mg.  Dec 4, 2021 .0285 mg.  Dec 11, 2021 .0265 mg. Dec 18, 2021 .0246 mg. Dec 25, 2021 .023mg. Jan 1, 2022. 0 mg. OFF COMPLETELY

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