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Lulupaige: Tapering off Seroquel and Abilify


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Hi I am a new member and am interested if anyone has tapered from seroquel and abilify successfully.  Interested in yr journey. 



prescribed 100mg 9/2011

increased to 200 mg 1/2016

tapered to 100 mg 6/2018

tapering to 50 mg 7/2018



prescribed 10mg 3/2010

tapered to 7 mg 3/2018

tapering to 5 mg 7/2018


Too soon for side effects for abilify and doing okay with seroquel.




3/2005 10 mg buspar 

7/2018 100 mg seroquel tapering to 75 mg

7/2018 7 mg abilify tapering to 5 mg

1/2018 200 mg wellbutrin

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  • ChessieCat changed the title to Lulupaige: Tapering off Seroquel and Abilify
  • Moderator

Hello, Lulupage, and welcome to SA.


First of all, could you copy what you've written about your drug history into a drug signature using the following link.  That was, the moderators can see your history without having to cross back to your original post.


Account Settings – Create or Edit a signature.


You are tapering both drugs far too quickly.  At Surviving Antidepressants, it is recommended that a person taper by no more than 10% of their current dose with at least a four week hold in-between decreases.  The 10% taper recommendation is a harm reduction approach to going off psychiatric drugs.  Some people may have to taper at a more conservative rate as they are sensitive to even the smallest drops.
We recommend tapering only one drug at a time.  Otherwise, if you have a problem, you won't be able to pinpoint which taper is causing it.  As the following link explains, we recommend tapering the more activating of the drugs first.


Gridley Introduction


Lexapro 20 mg since 2004.  Begin Brassmonkey Slide Taper Jan. 2017.   

End 2017 year 1 of taper at 9.25mg 

End 2018 year 2 of taper at 4.1mg

End 2019 year 3 of taper at 1.0mg  

Oct. 30, 2020  Jump to zero from 0.025mg.  Current dose: 0.000mg

3 year, 10 month taper is 100% complete.


Ativan 1 mg to 1.875mg 1986-2020, two CT's and reinstatements

Nov. 2020, 7-week Ativan-Valium crossover to 18.75mg Valium

Feb. 2021, begin 10%/4 week taper of 18.75mg   

End 2021  year 1 of taper at 6mg

End 2022 year 2 of taper at 2.75mg 

Current dose as of Feb. 25, 2023 2mg

Taper is 89% complete.


Imipramine 75 mg daily since 1986.  Jan-Sept 2016 tapered to 16mg  

Held until Aug 2021, tapered for 4 weeks to 14.4mg

March 22, 2022: Begin 10%/4 week taper

Aug. 5, 2022: hold at 9.5 and shift to Valium taper

Taper is 87% complete.  


Supplements: omega-3, vitamins C, E and D3, magnesium glycinate, probiotic, zinc, melatonin .3mg

I am not a medical professional and this is not medical advice but simply information based on my own experience, as well as other members who have survived these drugs.

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