Jump to content

Cannabis, marijuana, hashish, THC, & CBD (cannabidiol) or Hemp oil


Jonathan
 Share

Recommended Posts

very likely I have posted this before, but an excellent source for info on cannabis is found on Dr. Sulak's site. he does offered classes you have to pay for, but there is plenty of free info. correct dosing is vital! (mostly, people take a much higher dose than they should)  cannabis basics.

Currently taking Ramapril (blood pressure) 5 mg twice a day

Omeprazole 10 mg AM and 20 mg PM  (the taper has gone nowhere after the first cut)

Famotidine   once a day (and I still needs tums sometimes)

magnesium 200 mg at night

as of yesterday 2 fish oil capsules "EPA-DHA 1000"

 

off Lexapro as of 5/2018  - last dose had been 5 mg every other day for a couple years

 

highest dose had been 20 mg at which point I was diagnosed with Bipolar II, which went away when I cut the lexapro down to 15 mg. 

 

I spent years on Paxil before Lexapro (can't remember dose), briefly on Effexor and Abilify and others I have forgotten. in fact, when I was diagnoses with BPII I was put on all kinds of things which made me feel so bad I stopped them cold turkey within maybe 3 or 4 weeks, thank goodness. since then I've known these pills were terrible and I weaned down the Lexapro with zero help or support over I'm not sure how many years. 

 

Link to comment
Share on other sites

  • 2 weeks later...
On 7/14/2021 at 12:24 PM, hayduke said:

@Rbvdk yeah you have to consider that you're still dealing with a sensitised nervous system to some extent.

 

I've never been that big on the high THC strains either.

 

Lately I've found I can tolerate a pin joint once or twice a month but I pay for a day or three if I have more than that, or more often.

 

Haven't had any at all lately, or grog...and not minding it!  Not that weed doesn't have its uses, and I do love it, but since my baseline doesn't seem to include anxiety these days (yay therapy) I don't have that urge to self-medicate with them now.

Yeah that's true, I wish I could just chill out but annoyingly, the anxiety is back too ugh.

 

I'm so glad to hear you've had success with therapy, that's awesome! 🙂

16.4.14 - 25.4.15 Took Paxil (??mg) - cold turkey. Had random pgad symptoms around this time but not sure when exactly.

?.5.14: Started Citalopram (10mg) / 17.5.14: Quickly upped to 20mg  / 9?.15: upped to 30mg. 

8.16: Tapered off Citalopram in less than 2 weeks / 9.16: straight back on 20mg for just a week then stopped cold turkey. 11.16 Very mild pgad, PN symptoms and other withdrawals started.

7.12.16: Took Amitriptyline 10mg for just 2 days then stopped cold turkey.

14.12.16: reinstated 5mg of Citalopram / 1?.16: 10mg Citalopram / ?.16: 20mg Citalopram. 3.17 (6 months since withdrawing) pgad hit.

8.2.18: 15mg Citalopram / 8.3.18: 10mg / 8.4.18: 5mg / 12?.5.18: 2.5mg / 19.5.18: 0mg. pgad worsened almost instantly from first tapper, all sorts of PN symptoms, earworm, tinnitus, other things, coming and going until late 9.18 (4 months since 0mg) where it all got SO MUCH worse for 1.11 years (with windows and waves).

1.9.20: 99% healed ❤️

31.5.21: Smoked weed 5 out of 9 days. Pgad and other old withdrawals came back, plus developed akathesia & fibromyalgia.

7.22: Steadily recovering again ❤

Link to comment
Share on other sites

  • 2 weeks later...
  • Moderator

I hate the title, but some good information on CBD or cannabidiol, the legal, over the counter stuff, with less than or equal to 0.3 % THC in it.

 

Pharmacology AND drug interactions.  AND if you scroll down it does indeed mention the probably withdrawal from, if taken regularly for a period of time.

Under the CBD and addiction heading there:

"Withdrawal symptoms are not well described in the literature but however, most likely a person who takes CBD regularly for insomnia, will experience rebound insomnia if he stops [81].

Similar exacerbating effects are to be expected when CBD is no longer taken for depression or anxiety [12, 42]. Studies about the withdrawal symptoms from CBD and their course are yet to be published. Only case reports exist."

Which would lead me to believe one should plan on some sort of taper, if using this on a regular basis when they decide to quit.

 

Dig in:

The Impact of Cannabidiol on Psychiatric and Medical Conditions

This article is a systematic review of literature reviewing the available clinical data on CBD, for use in various medical and psychiatric conditions with focus on a review of the pharmacology and toxicity.

Edited by manymoretodays

2022 May- continuing with limited activity on site, just something I need to do right now

Started with psycho meds/psychiatric care circa 1988.  In retrospect, and on contemplation, situational overwhelm.

Rounding up to 30 years of medications(30 medication trials, poly-pharmacy maximum was 3 at one time).

5/28/2015-off Adderal salts 2.5mg. (I had been on that since hospital 10/2014)

12/2015---just holding, holding, holding, with trileptal/oxcarb at 75 mg. 1/2 tab at hs.  My last psycho med ever!  Tapered @ 10% every 4 weeks, sometimes 2 weeks to

2016 Dec 16 medication free!!

Longer signature post here, with current supplements.

Herb and alcohol free since 5/15/2016.  And.....I quit smoking 11/2021.  Can you say Hallelujah?(took me long enough)💜

None of my posts are intended as medical advice.  Please discuss any decisions about your medical care with a knowledgeable medical provider. manymoretodays

 

Link to comment
Share on other sites

Tbh I haven't found any withdrawal effects and I stopped after about it a month, and I am super sensitive. But who knows.

10 years on various anti-depressants

5 years Effexor xr

tappered of 150mg in 6 months

nothing for two weeks

Reinstated 15 beads for 50 days

Tappered off then clean 2-3months

gradually went back up to 13 mg 3 years

bridged fluoxetine 10mg

2 week tapper

1 year clean

reinstated 5ml dispersed fluroxatine for 6months

 

Link to comment
Share on other sites

  • 1 month later...

@Rbvdk How are you man?

I'm like you, I healed 75% but the last sunday I smoked brick weed, about 3 hour I got paranoid(people who starred at me and hurt me) then I slept 5 hours on that day.

I went for a friends marriage which about 70 miles away from my home.

Next morning I came to my home and got slept 2 hour sleep afterwards I went for Job nothing happens at that day.

On Tuesday from morning to evening also nice man about night I fought with my little sister for cream cookies after the fight my whole body got little tremors and I went to bed, I slept about 8 hrs man,

On Wednesday morning I had bath to go for work and meditate myself and went to yougurt drink for my stomach irriation(when i gets irriation bloated stomach I goes to have yougurt). Shop guy who served yougurt stare at me and I drank yougurt then all people stare at me like symptoms I got and went to my work and asked my co worker what today I got racing heart beat(I think that heart palpitations) then I left my shop to home quickly When I reached home I sit in a chair I distracted my paranoid thoughts.

I didn't have any symptoms as I mentioned here was not in my Withdrawl.

From Thursday I felt paranoid in morning and today also I get paranoid.

If my mama worried, the paranoid hit the roof.

I also gets brain fog, memory impairment.

I feels these symptoms aren't had in tapering Withdrawal,

I hope you can help me Out from this.

(6 Aug 2019 start taper 4.8mg, 5 Sep - 4mg,

16 oct 19- 3mg, 28 nov 19 - 2mg, 11 may 20 -1mg

1 oct 20- 0.5mg, 24 dec 20 - 0.25mg,

5 jan 21- 0.2375, 9 jan 21 - 0.225, 13 jan 21 - 0.2125,

17 jan 21-  0.2, 21 jan 21 - 0.1875, 25 jan 21 - 0.175,

29 jan 21 - 0.1625, 2 feb 21 - 0.15, 6 feb 21 - 0.1375,

10 feb 21 - 0.125, 14 feb 21 - 0.1125, 18 feb 21 - 0.1, 

22 feb  - 0.0875, 26 feb - 0.075 , 2 mar - 0.0625, 

9 mar - 0.05625, 13 mar- .05, 17 mar - 0.04375,

 22 mar- 0.0375, 27 mar- .03125, 31 mar- 0.025

At 9 Apr - 0.0125 From 10 Apr - 0.0000 )

End game Taper from  0.5mg to 0.125mg

Link to comment
Share on other sites

  • 3 months later...

Lexapro (escitalopram) possible interaction with CBD oil (caution)

 

Lexapro is the brand name for a drug called escitalopram. It is a selective serotonin reuptake inhibitor (SSRI). SSRIs are a class of antidepressant. They’re used to treat major depressive disorder and generalized anxiety disorder.

 

CBD (cannabidiol) is one of the many active compounds found in cannabis. These compounds are called cannabinoids. Unlike its cousin THC (delta-9-tetrahydrocannabinol), CBD does not cause an intoxicating ‘high.’

However, that is not to say that CBD has no psychoactive effects whatsoever. In fact, it has become well known for its supposed anti-anxiety and antidepressant properties.

Nowadays, more people are turning to CBD to relieve the symptoms of anxiety and depression. However, scientists are still trying to ascertain exactly how the cannabinoid works for these conditions.

 

This post it is meant to prevent and explain a possible interaction with this 2 drugs, although CBD can be recognized as a supplement or a herb also. 

 

 

The following enzymes metabolize Lexapro:

  • CYP3A4
  • CYP2D6
  • CYP2C19

The CYP450 pathway also metabolizes CBD in the liver. The specific enzymes responsible for breaking down CBD are:

  • CYP3A4
  • CYP2C9
  • CYP2C19

As it turns out, CBD inhibits the enzymes CYP3A4 and CYP2C6. As you can see, Lexapro and CBD share many of the same enzymatic pathways and, therefore, have a strong chance of interacting.

 

So the downside is that taking CBD alongside Lexapro may increase the amount of antidepressants in the body. One might assume this is a positive thing, but it significantly increases the risk of harmful side effects if taken together.

It is recommended that anyone wanting to try CBD for depression / anxiety should stop taking their medication first and then make the switch. However, it is essential that one does this gradually, carefully like we all know from all the information we have on here.

 

Combining this two can outcome the risk or severity of serotonin syndrome, also noted the fact that combining any A/D with CBD oil can increase the risk or severity of adverse effects.

 

In conclusion, both Lexapro and CBD oil are popular remedies for depression and anxiety. However, taking the two together may cause a drug interaction as they are both metabolized by the same enzymes in the liver.

 

Relevant links :

https://wayofleaf.com/cbd/101/does-cbd-oil-interact-with-lexapro

https://go.drugbank.com/drugs/DB01175

 

Edited by ChessieCat
added topic title before merging with existing topic

27/04/21 Escitalopram x 2.5mg Clonazepam 0.375 mg | 14/05/21 Escitalopram x 5mg Clonazepam x 0.5 mg | 30/05/21 Escitalopram x 7.5mg Clonazepam x 0.375 mg | 14/06/21 Escitalopram x 10mg Clonazepam x 0.25 mg | 27/08/21  Escitalopram x 5mg Clonazepam x 0.5 mg |

28/08/21 Escitalopram x 5mg Clonazepam x 0.475 mg | 04/09/21 Escitalopram x 5mg Clonazepam x 0.4 mg | 09/09/21 Escitalopram x 5mg Clonazepam x 0.35 mg | 14/09/21  Escitalopram x 5 mg Clonazepam x 0.3 mg | 14/10/2021 Escitalopram x 4mg Clonazepam x 0.3 mg | 22/10/21 Escitalopram x 4.5mg Clonazepam x 0.3 mg | 19/11/21 Escitalopram x 4mg Clonazepam x 0.3 mg | 29/12/21 Escitalopram x 3.92 mg Clonazepam x 0.3 mg | 2/1/2022 Escitalopram x 3.84 mg Clonazepam x 0.3 mg | 7/1/2022 Escitalopram x 3.76 mg Clonazepam x 0.3 mg | 7/1/2022 Escitalopram x 3.76 mg Clonazepam x 0.3 mg | 17/05/22  Escitalopram x 3.36 mg Diazepam x 14 mg | 12/06/22 Escitalopram x 2.92 mg Diazepam x 14 mg | 01/08/22 Escitalopram x 2.61 mg Diazepam x 14 mg

 

Supplements:  Omega 3 , Magnesium Threonate

 

Link to comment
Share on other sites

  • 3 months later...

Think I reacted badly on CBD oil, sorry to say.

Zoloft, November 2019.  I worked up to 50 mg and stayed there until 1 year later. I tapered for 3 months, which should consider to be cold turkey.
Tapering schedule:
Month 1: 37.5 mg

Month 2: 25 mg

Month 3: 12.5 mg

Month 4(Half the month): 6.75 mg
Month 4(Other half): 0 mg December 9, 2020

Link to comment
Share on other sites

  • Moderator

I couldn't afford CBD oil.  I was also a bit concerned it might be a bit of a crutch I would also have to untangle from later on.  Though it's probably helpful for some people in some cases.

What I did find, because I hate fish oil, was that hemp protein powder is the other major viable source of Omega 3.  Now I scoff it down regularly.  While it probably isn't THC or heavily CBD related, I don't think it's contentious that this plant has many health benefits among its various forms.

I find this is a reliable meal for alleviating anxiety a few times a week, and isn't bad in yoghurt.

 

I am not a health professional - your actions are your own.  

Please do not seek tapering support via private message

My taper visualised as a graph   |   My intro thread

Backdrop:  2003 10mg olanzapine | 2004 2-3mg risperidone | end 2014 3wks aripiprazole

2015: olanzapine  10 -> 7½ -> 6⅔ -> 5mg  by crude pill cutter

2018:  Mar 5.00mg -> water titrated taper -> Aug2.5mg tablet and hold

Jan 2019 2.50mg water titration -> Jan 2020 1.214  -> Jan 2021 0.44 -> 2 Oct 0.205 ->3 Oct ZERO🥂

"Ask not what you can do for your country, but what your country did to you"  -- KMFDM

Link to comment
Share on other sites

  • 2 months later...

The last drop in fluoxetine was a 20% drop which is a big drop for me, usually I do the recommended 10% or less. 

Through the weeks before and after the drop  I took CBD oil and smoked Charlottes web and came away with a very mild withdrawal. 

 

It has been close to four months now so I feel like I escaped any major unpleasantness, I waited to comment in this thread as I worried the the withdrawal was just delayed.

 

I stopped taking any cbd a bout 3 weeks after my drop, I wasn't taking cbd consistently, usually just before bed or in the middle of night with oil. I really wish I wrote down the exact times I was taking it and how much, but the times were all over the place anyway. It's hard to say how much when smoking it too, but it was a very small amount and I found that when you smoked it it was fast acting and more powerful, usually putting me to sleep.

 

 

This weekend I'm going to do another drop. 

10 years on various anti-depressants

5 years Effexor xr

tappered of 150mg in 6 months

nothing for two weeks

Reinstated 15 beads for 50 days

Tappered off then clean 2-3months

gradually went back up to 13 mg 3 years

bridged fluoxetine 10mg

2 week tapper

1 year clean

reinstated 5ml dispersed fluroxatine for 6months

 

Link to comment
Share on other sites

  • 4 weeks later...
On 6/3/2022 at 9:21 PM, SouthernFreeze said:

The last drop in fluoxetine was a 20% drop which is a big drop for me, usually I do the recommended 10% or less. 

Through the weeks before and after the drop  I took CBD oil and smoked Charlottes web and came away with a very mild withdrawal. 

 

It has been close to four months now so I feel like I escaped any major unpleasantness, I waited to comment in this thread as I worried the the withdrawal was just delayed.

 

I stopped taking any cbd a bout 3 weeks after my drop, I wasn't taking cbd consistently, usually just before bed or in the middle of night with oil. I really wish I wrote down the exact times I was taking it and how much, but the times were all over the place anyway. It's hard to say how much when smoking it too, but it was a very small amount and I found that when you smoked it it was fast acting and more powerful, usually putting me to sleep.

 

 

This weekend I'm going to do another drop. 


You are one of the lucky ones, for me CBD, oil or vaped has interfered with the meds many times, it works on the day it is taken, then suffer days / weeks because of it…

27/04/21 Escitalopram x 2.5mg Clonazepam 0.375 mg | 14/05/21 Escitalopram x 5mg Clonazepam x 0.5 mg | 30/05/21 Escitalopram x 7.5mg Clonazepam x 0.375 mg | 14/06/21 Escitalopram x 10mg Clonazepam x 0.25 mg | 27/08/21  Escitalopram x 5mg Clonazepam x 0.5 mg |

28/08/21 Escitalopram x 5mg Clonazepam x 0.475 mg | 04/09/21 Escitalopram x 5mg Clonazepam x 0.4 mg | 09/09/21 Escitalopram x 5mg Clonazepam x 0.35 mg | 14/09/21  Escitalopram x 5 mg Clonazepam x 0.3 mg | 14/10/2021 Escitalopram x 4mg Clonazepam x 0.3 mg | 22/10/21 Escitalopram x 4.5mg Clonazepam x 0.3 mg | 19/11/21 Escitalopram x 4mg Clonazepam x 0.3 mg | 29/12/21 Escitalopram x 3.92 mg Clonazepam x 0.3 mg | 2/1/2022 Escitalopram x 3.84 mg Clonazepam x 0.3 mg | 7/1/2022 Escitalopram x 3.76 mg Clonazepam x 0.3 mg | 7/1/2022 Escitalopram x 3.76 mg Clonazepam x 0.3 mg | 17/05/22  Escitalopram x 3.36 mg Diazepam x 14 mg | 12/06/22 Escitalopram x 2.92 mg Diazepam x 14 mg | 01/08/22 Escitalopram x 2.61 mg Diazepam x 14 mg

 

Supplements:  Omega 3 , Magnesium Threonate

 

Link to comment
Share on other sites

On 3/22/2022 at 3:48 AM, curiousnootropics said:

Think I reacted badly on CBD oil, sorry to say.

Are you on any meds or off? 

27/04/21 Escitalopram x 2.5mg Clonazepam 0.375 mg | 14/05/21 Escitalopram x 5mg Clonazepam x 0.5 mg | 30/05/21 Escitalopram x 7.5mg Clonazepam x 0.375 mg | 14/06/21 Escitalopram x 10mg Clonazepam x 0.25 mg | 27/08/21  Escitalopram x 5mg Clonazepam x 0.5 mg |

28/08/21 Escitalopram x 5mg Clonazepam x 0.475 mg | 04/09/21 Escitalopram x 5mg Clonazepam x 0.4 mg | 09/09/21 Escitalopram x 5mg Clonazepam x 0.35 mg | 14/09/21  Escitalopram x 5 mg Clonazepam x 0.3 mg | 14/10/2021 Escitalopram x 4mg Clonazepam x 0.3 mg | 22/10/21 Escitalopram x 4.5mg Clonazepam x 0.3 mg | 19/11/21 Escitalopram x 4mg Clonazepam x 0.3 mg | 29/12/21 Escitalopram x 3.92 mg Clonazepam x 0.3 mg | 2/1/2022 Escitalopram x 3.84 mg Clonazepam x 0.3 mg | 7/1/2022 Escitalopram x 3.76 mg Clonazepam x 0.3 mg | 7/1/2022 Escitalopram x 3.76 mg Clonazepam x 0.3 mg | 17/05/22  Escitalopram x 3.36 mg Diazepam x 14 mg | 12/06/22 Escitalopram x 2.92 mg Diazepam x 14 mg | 01/08/22 Escitalopram x 2.61 mg Diazepam x 14 mg

 

Supplements:  Omega 3 , Magnesium Threonate

 

Link to comment
Share on other sites

  • Mentor

@lex1989  Did you  end up trying the CBD and vaping like you mentioned the other week?

https://www.survivingantidepressants.org/topic/24894-greatful-is-this-withdrawal-or-to-many-med-changes-at-once/

1995? Prozac,  tried several Paxil, Serzone, St John's Wart back to Prozac and Trazodone ct:d Traz

 Lexapro. Tried to stop Crash in 2015  Kindled   Hospitalized, Vybrid, Seroquel, Effexor, Abilify  Pristiq, Wellbutrin-- 2016  ended back on   Prozac and Lamictal 200mg

5/2020  thru 12/2020 taper from 20mg  Prozac  down to 3mg.  Crashed  12/13/2020 Zoloft 50mg 1/29ct  1/29/2021 Seroquel 50mg ct  2/12/2021 Wellbutrin 75mg.  Became hypo manic 2/1  6ct Trazadone 50mg 4/25  25mg 2/5/ 2021 Lamictal 150mg.  2/24  100mg   4/9  75mg   4/21 37.5 

2/16/2021 Seroquel 50xr  3/3 100mg  3/17  150mg  side effects ct   4/3 2021 Lexapro 5mg  4/14  7.5mg  4/30 10mg  5/10  7.5mg 

2021/ 5/16  5mg Lexapro   37.5 Lamictal   25mg trazadone,   xanax  .0625mg  3x a day   Magnesium glycinate 300 to 400mg a day 

Lexapro   Sept/01/2021  4.90mg  Sept/25  4.75mg   Oct/19 4.69mg  Nov/14 4.2mg    Jan/30/2022-- All liquid  4.2mg  (2.20mg at 8am & 2mg at 4pm) 2/17 4mg  2/24  3.8mg   3/21 3.4mg  5/2 3mg  6/1  decreasing by 0.02ml  daily  to 2.70 mg  7/1 decreasing 0.02ml daily to  2.5 mg 8/1 decreasing 0.02ml daily to 2.3mg

Lamictal 25mg

 

Link to comment
Share on other sites

Curious as well. I tried some cbd gummies when I was having sleep issues. Didn't really feel anything but I only took 20 mgs.  

2008: March, Klonopin .5 mg to 1 mg

2009: Dec, CT Klonopin

2010: full year heavy alcohol use

2011: Jan - withdrawals start

2012: Apr- bad wave, start zoloft 50

2014 to 2020: Switch ADs

Sertraline 100mgs >Lexapro 20 mgs>Prozac 20 mgs >Lexapro 20

2021: Sertraline 25 mgs

2022: Mar. Cut dose down to 12.5

End of May, starting to crash physically/mentally.

 

Link to comment
Share on other sites

 Share

×
×
  • Create New...

Important Information

Terms of Use Privacy Policy