JackieDecides Posted July 18, 2021 Share Posted July 18, 2021 very likely I have posted this before, but an excellent source for info on cannabis is found on Dr. Sulak's site. he does offered classes you have to pay for, but there is plenty of free info. correct dosing is vital! (mostly, people take a much higher dose than they should) cannabis basics. 1 Currently taking Ramapril (blood pressure) 5 mg twice a day Omeprazole 10 mg AM and 20 mg PM (the taper has gone nowhere after the first cut) Famotidine once a day (and I still needs tums sometimes) magnesium 200 mg at night as of yesterday 2 fish oil capsules "EPA-DHA 1000" off Lexapro as of 5/2018 - last dose had been 5 mg every other day for a couple years highest dose had been 20 mg at which point I was diagnosed with Bipolar II, which went away when I cut the lexapro down to 15 mg. I spent years on Paxil before Lexapro (can't remember dose), briefly on Effexor and Abilify and others I have forgotten. in fact, when I was diagnoses with BPII I was put on all kinds of things which made me feel so bad I stopped them cold turkey within maybe 3 or 4 weeks, thank goodness. since then I've known these pills were terrible and I weaned down the Lexapro with zero help or support over I'm not sure how many years. Link to comment Share on other sites More sharing options...
Rbvdk Posted July 28, 2021 Share Posted July 28, 2021 On 7/14/2021 at 12:24 PM, hayduke said: @Rbvdk yeah you have to consider that you're still dealing with a sensitised nervous system to some extent. I've never been that big on the high THC strains either. Lately I've found I can tolerate a pin joint once or twice a month but I pay for a day or three if I have more than that, or more often. Haven't had any at all lately, or grog...and not minding it! Not that weed doesn't have its uses, and I do love it, but since my baseline doesn't seem to include anxiety these days (yay therapy) I don't have that urge to self-medicate with them now. Yeah that's true, I wish I could just chill out but annoyingly, the anxiety is back too ugh. I'm so glad to hear you've had success with therapy, that's awesome! 🙂 16.4.14 - 25.4.15 Took Paxil (??mg) - cold turkey. Had random pgad symptoms around this time but not sure when exactly. ?.5.14: Started Citalopram (10mg) / 17.5.14: Quickly upped to 20mg / 9?.15: upped to 30mg. 8.16: Tapered off Citalopram in less than 2 weeks / 9.16: straight back on 20mg for just a week then stopped cold turkey. 11.16 Very mild pgad, PN symptoms and other withdrawals started. 7.12.16: Took Amitriptyline 10mg for just 2 days then stopped cold turkey. 14.12.16: reinstated 5mg of Citalopram / 1?.16: 10mg Citalopram / ?.16: 20mg Citalopram. 3.17 (6 months since withdrawing) pgad hit. 8.2.18: 15mg Citalopram / 8.3.18: 10mg / 8.4.18: 5mg / 12?.5.18: 2.5mg / 19.5.18: 0mg. pgad worsened almost instantly from first tapper, all sorts of PN symptoms, earworm, tinnitus, other things, coming and going until late 9.18 (4 months since 0mg) where it all got SO MUCH worse for 1.11 years (with windows and waves). 1.9.20: 99% healed ❤️ 31.5.21: Smoked weed 5 out of 9 days. Pgad and other old withdrawals came back, plus developed akathesia & fibromyalgia. 7.22: Steadily recovering again ❤ 2.23: Acute withdrawals coming back, no apparent reason. Link to comment Share on other sites More sharing options...
Moderator Emeritus manymoretodays Posted August 6, 2021 Moderator Emeritus Share Posted August 6, 2021 (edited) I hate the title, but some good information on CBD or cannabidiol, the legal, over the counter stuff, with less than or equal to 0.3 % THC in it. Pharmacology AND drug interactions. AND if you scroll down it does indeed mention the probably withdrawal from, if taken regularly for a period of time. Under the CBD and addiction heading there: "Withdrawal symptoms are not well described in the literature but however, most likely a person who takes CBD regularly for insomnia, will experience rebound insomnia if he stops [81]. Similar exacerbating effects are to be expected when CBD is no longer taken for depression or anxiety [12, 42]. Studies about the withdrawal symptoms from CBD and their course are yet to be published. Only case reports exist." Which would lead me to believe one should plan on some sort of taper, if using this on a regular basis when they decide to quit. Dig in: The Impact of Cannabidiol on Psychiatric and Medical Conditions This article is a systematic review of literature reviewing the available clinical data on CBD, for use in various medical and psychiatric conditions with focus on a review of the pharmacology and toxicity. Edited August 6, 2021 by manymoretodays Late 2023- gone to emeritus status, inactive, don't @ me, I can check who I've posted on, and I'm not really here like I used to be......thanks. Started with psycho meds/psychiatric care circa 1988. In retrospect, and on contemplation, situational overwhelm. Rounding up to 30 years of medications(30 medication trials, poly-pharmacy maximum was 3 at one time). 5/28/2015-off Adderal salts 2.5mg. (I had been on that since hospital 10/2014) 12/2015---just holding, holding, holding, with trileptal/oxcarb at 75 mg. 1/2 tab at hs. My last psycho med ever! Tapered @ 10% every 4 weeks, sometimes 2 weeks to 2016 Dec 16, medication free!! Longer signature post here, with current supplements. Herb and alcohol free since 5/15/2016. And.....I quit smoking 11/2021. Lapsed. Redo of quit smoking 9/28/2022. Can you say Hallelujah?(took me long enough)💜 None of my posts are intended as medical advice. Please discuss any decisions about your medical care with a knowledgeable medical provider. My success story: Blue skies ahead, clear sailing Link to comment Share on other sites More sharing options...
SouthernFreeze Posted August 6, 2021 Share Posted August 6, 2021 Tbh I haven't found any withdrawal effects and I stopped after about it a month, and I am super sensitive. But who knows. 1 10 years on various anti-depressants 5 years Effexor xr tappered of 150mg in 6 months nothing for two weeks Reinstated 15 beads for 50 days Tappered off then clean 2-3months gradually went back up to 13 mg 3 years bridged fluoxetine 10mg 2 week tapper 1 year clean reinstated 5ml dispersed fluroxatine for 6months Link to comment Share on other sites More sharing options...
Miyan Posted September 10, 2021 Share Posted September 10, 2021 @Rbvdk How are you man? I'm like you, I healed 75% but the last sunday I smoked brick weed, about 3 hour I got paranoid(people who starred at me and hurt me) then I slept 5 hours on that day. I went for a friends marriage which about 70 miles away from my home. Next morning I came to my home and got slept 2 hour sleep afterwards I went for Job nothing happens at that day. On Tuesday from morning to evening also nice man about night I fought with my little sister for cream cookies after the fight my whole body got little tremors and I went to bed, I slept about 8 hrs man, On Wednesday morning I had bath to go for work and meditate myself and went to yougurt drink for my stomach irriation(when i gets irriation bloated stomach I goes to have yougurt). Shop guy who served yougurt stare at me and I drank yougurt then all people stare at me like symptoms I got and went to my work and asked my co worker what today I got racing heart beat(I think that heart palpitations) then I left my shop to home quickly When I reached home I sit in a chair I distracted my paranoid thoughts. I didn't have any symptoms as I mentioned here was not in my Withdrawl. From Thursday I felt paranoid in morning and today also I get paranoid. If my mama worried, the paranoid hit the roof. I also gets brain fog, memory impairment. I feels these symptoms aren't had in tapering Withdrawal, I hope you can help me Out from this. (6 Aug 2019 start taper 4.8mg, 5 Sep - 4mg, 16 oct 19- 3mg, 28 nov 19 - 2mg, 11 may 20 -1mg 1 oct 20- 0.5mg, 24 dec 20 - 0.25mg, 5 jan 21- 0.2375, 9 jan 21 - 0.225, 13 jan 21 - 0.2125, 17 jan 21- 0.2, 21 jan 21 - 0.1875, 25 jan 21 - 0.175, 29 jan 21 - 0.1625, 2 feb 21 - 0.15, 6 feb 21 - 0.1375, 10 feb 21 - 0.125, 14 feb 21 - 0.1125, 18 feb 21 - 0.1, 22 feb - 0.0875, 26 feb - 0.075 , 2 mar - 0.0625, 9 mar - 0.05625, 13 mar- .05, 17 mar - 0.04375, 22 mar- 0.0375, 27 mar- .03125, 31 mar- 0.025 At 9 Apr - 0.0125 From 10 Apr - 0.0000 ) End game Taper from 0.5mg to 0.125mg Link to comment Share on other sites More sharing options...
lex1989 Posted December 17, 2021 Share Posted December 17, 2021 (edited) Lexapro (escitalopram) possible interaction with CBD oil (caution) Lexapro is the brand name for a drug called escitalopram. It is a selective serotonin reuptake inhibitor (SSRI). SSRIs are a class of antidepressant. They’re used to treat major depressive disorder and generalized anxiety disorder. CBD (cannabidiol) is one of the many active compounds found in cannabis. These compounds are called cannabinoids. Unlike its cousin THC (delta-9-tetrahydrocannabinol), CBD does not cause an intoxicating ‘high.’ However, that is not to say that CBD has no psychoactive effects whatsoever. In fact, it has become well known for its supposed anti-anxiety and antidepressant properties. Nowadays, more people are turning to CBD to relieve the symptoms of anxiety and depression. However, scientists are still trying to ascertain exactly how the cannabinoid works for these conditions. This post it is meant to prevent and explain a possible interaction with this 2 drugs, although CBD can be recognized as a supplement or a herb also. The following enzymes metabolize Lexapro: CYP3A4 CYP2D6 CYP2C19 The CYP450 pathway also metabolizes CBD in the liver. The specific enzymes responsible for breaking down CBD are: CYP3A4 CYP2C9 CYP2C19 As it turns out, CBD inhibits the enzymes CYP3A4 and CYP2C6. As you can see, Lexapro and CBD share many of the same enzymatic pathways and, therefore, have a strong chance of interacting. So the downside is that taking CBD alongside Lexapro may increase the amount of antidepressants in the body. One might assume this is a positive thing, but it significantly increases the risk of harmful side effects if taken together. It is recommended that anyone wanting to try CBD for depression / anxiety should stop taking their medication first and then make the switch. However, it is essential that one does this gradually, carefully like we all know from all the information we have on here. Combining this two can outcome the risk or severity of serotonin syndrome, also noted the fact that combining any A/D with CBD oil can increase the risk or severity of adverse effects. In conclusion, both Lexapro and CBD oil are popular remedies for depression and anxiety. However, taking the two together may cause a drug interaction as they are both metabolized by the same enzymes in the liver. Relevant links : https://wayofleaf.com/cbd/101/does-cbd-oil-interact-with-lexapro https://go.drugbank.com/drugs/DB01175 Edited December 17, 2021 by ChessieCat added topic title before merging with existing topic 1 27/04/21 Escitalopram x 2.5mg Clonazepam 0.375 mg | 14/05/21 Escitalopram x 5mg Clonazepam x 0.5 mg | 30/05/21 Escitalopram x 7.5mg Clonazepam x 0.375 mg | 14/06/21 Escitalopram x 10mg Clonazepam x 0.25 mg | 27/08/21 Escitalopram x 5mg Clonazepam x 0.5 mg | 28/08/21 Escitalopram x 5mg Clonazepam x 0.475 mg | 04/09/21 Escitalopram x 5mg Clonazepam x 0.4 mg | 09/09/21 Escitalopram x 5mg Clonazepam x 0.35 mg | 14/09/21 Escitalopram x 5 mg Clonazepam x 0.3 mg | 14/10/2021 Escitalopram x 4mg Clonazepam x 0.3 mg | 22/10/21 Escitalopram x 4.5mg Clonazepam x 0.3 mg | 19/11/21 Escitalopram x 4mg Clonazepam x 0.3 mg | 29/12/21 Escitalopram x 3.92 mg Clonazepam x 0.3 mg | 2/1/2022 Escitalopram x 3.84 mg Clonazepam x 0.3 mg | 7/1/2022 Escitalopram x 3.76 mg Clonazepam x 0.3 mg | 7/1/2022 Escitalopram x 3.76 mg Clonazepam x 0.3 mg | 17/05/22 Escitalopram x 3.36 mg Diazepam x 14 mg | 12/06/22 Escitalopram x 2.92 mg Diazepam x 14 mg | 01/08/22 Escitalopram x 2.61 mg Diazepam x 14 mg | 29/08/22 Escitalopram x 2.46 mg Diazepam x 14 mg | 1/11/22 Escitalopram x 2 mg Diazepam x 14 mg | 28/11/22 Escitalopram x 1.61 mg Diazepam x 14 mg | 09/01/23 Escitalopram x 1.30 mg Diazepam x 14 mg | 09/02/23 Escitalopram x 1 mg Diazepam x 14 mg | 09/03/23 Escitalopram x 0.76 mg Diazepam x 14 mg | 09/04/23 Escitalopram x 0.54 mg Diazepam x 14 mg | 08/05/23 Escitalopram x 0.31 mg Diazepam x 14 mg | 06/06/23 Escitalopram x 0.15 mg Diazepam x 14 mg | 04/07/23 Lexapro FREE Diazepam x 14 mg | 10/09/23 Lexapro FREE Diazepam x 13 mg | 02/10/23 Diazepam x 12 mg | 23/10/23 Diazepam x 10 mg | Link to comment Share on other sites More sharing options...
curiousnootropics Posted March 22, 2022 Share Posted March 22, 2022 Think I reacted badly on CBD oil, sorry to say. Zoloft, November 2019. I worked up to 50 mg and stayed there until 1 year later. I tapered for 3 months, which should consider to be cold turkey. Tapering schedule: Month 1: 37.5 mg Month 2: 25 mg Month 3: 12.5 mg Month 4(Half the month): 6.75 mg Month 4(Other half): 0 mg December 9, 2020 Link to comment Share on other sites More sharing options...
Moderator hayduke Posted March 24, 2022 Moderator Share Posted March 24, 2022 I couldn't afford CBD oil. I was also a bit concerned it might be a bit of a crutch I would also have to untangle from later on. Though it's probably helpful for some people in some cases. What I did find, because I hate fish oil, was that hemp protein powder is the other major viable source of Omega 3. Now I scoff it down regularly. While it probably isn't THC or heavily CBD related, I don't think it's contentious that this plant has many health benefits among its various forms. I find this is a reliable meal for alleviating anxiety a few times a week, and isn't bad in yoghurt. I am not a health professional - your actions are your own. Please do not seek tapering support via private message - "Any reason to hold is a good one" My taper visualised as a graph | My intro thread Backdrop: 2003 10mg olanzapine | 2004 2-3mg risperidone | end 2014 3wks aripiprazole 2015: olanzapine 10 -> 7½ -> 6⅔ -> 5mg by crude pill cutter 2018: Mar 5.00mg -> water titrated taper -> Aug2.5mg tablet and hold Jan 2019 2.50mg water titration -> Jan 2020 1.214 -> Jan 2021 0.44 -> 2 Oct 0.205 ->3 Oct ZERO🥂 Jun 2023 💉150mg paliperidone "loading" depot shot, 100mg 1wk after Jul 100mg Aug-Dec 75mg/4wks Jul 2023 2.50mg aripiprazole/day attempt to lower prolactin^ Jan-Feb 2024 cross taper off shots to 1mg risperidone Ask not what you can do for your country, but what your country did to you" -- KMFDM Link to comment Share on other sites More sharing options...
SouthernFreeze Posted June 3, 2022 Share Posted June 3, 2022 The last drop in fluoxetine was a 20% drop which is a big drop for me, usually I do the recommended 10% or less. Through the weeks before and after the drop I took CBD oil and smoked Charlottes web and came away with a very mild withdrawal. It has been close to four months now so I feel like I escaped any major unpleasantness, I waited to comment in this thread as I worried the the withdrawal was just delayed. I stopped taking any cbd a bout 3 weeks after my drop, I wasn't taking cbd consistently, usually just before bed or in the middle of night with oil. I really wish I wrote down the exact times I was taking it and how much, but the times were all over the place anyway. It's hard to say how much when smoking it too, but it was a very small amount and I found that when you smoked it it was fast acting and more powerful, usually putting me to sleep. This weekend I'm going to do another drop. 10 years on various anti-depressants 5 years Effexor xr tappered of 150mg in 6 months nothing for two weeks Reinstated 15 beads for 50 days Tappered off then clean 2-3months gradually went back up to 13 mg 3 years bridged fluoxetine 10mg 2 week tapper 1 year clean reinstated 5ml dispersed fluroxatine for 6months Link to comment Share on other sites More sharing options...
lex1989 Posted June 29, 2022 Share Posted June 29, 2022 On 6/3/2022 at 9:21 PM, SouthernFreeze said: The last drop in fluoxetine was a 20% drop which is a big drop for me, usually I do the recommended 10% or less. Through the weeks before and after the drop I took CBD oil and smoked Charlottes web and came away with a very mild withdrawal. It has been close to four months now so I feel like I escaped any major unpleasantness, I waited to comment in this thread as I worried the the withdrawal was just delayed. I stopped taking any cbd a bout 3 weeks after my drop, I wasn't taking cbd consistently, usually just before bed or in the middle of night with oil. I really wish I wrote down the exact times I was taking it and how much, but the times were all over the place anyway. It's hard to say how much when smoking it too, but it was a very small amount and I found that when you smoked it it was fast acting and more powerful, usually putting me to sleep. This weekend I'm going to do another drop. You are one of the lucky ones, for me CBD, oil or vaped has interfered with the meds many times, it works on the day it is taken, then suffer days / weeks because of it… 27/04/21 Escitalopram x 2.5mg Clonazepam 0.375 mg | 14/05/21 Escitalopram x 5mg Clonazepam x 0.5 mg | 30/05/21 Escitalopram x 7.5mg Clonazepam x 0.375 mg | 14/06/21 Escitalopram x 10mg Clonazepam x 0.25 mg | 27/08/21 Escitalopram x 5mg Clonazepam x 0.5 mg | 28/08/21 Escitalopram x 5mg Clonazepam x 0.475 mg | 04/09/21 Escitalopram x 5mg Clonazepam x 0.4 mg | 09/09/21 Escitalopram x 5mg Clonazepam x 0.35 mg | 14/09/21 Escitalopram x 5 mg Clonazepam x 0.3 mg | 14/10/2021 Escitalopram x 4mg Clonazepam x 0.3 mg | 22/10/21 Escitalopram x 4.5mg Clonazepam x 0.3 mg | 19/11/21 Escitalopram x 4mg Clonazepam x 0.3 mg | 29/12/21 Escitalopram x 3.92 mg Clonazepam x 0.3 mg | 2/1/2022 Escitalopram x 3.84 mg Clonazepam x 0.3 mg | 7/1/2022 Escitalopram x 3.76 mg Clonazepam x 0.3 mg | 7/1/2022 Escitalopram x 3.76 mg Clonazepam x 0.3 mg | 17/05/22 Escitalopram x 3.36 mg Diazepam x 14 mg | 12/06/22 Escitalopram x 2.92 mg Diazepam x 14 mg | 01/08/22 Escitalopram x 2.61 mg Diazepam x 14 mg | 29/08/22 Escitalopram x 2.46 mg Diazepam x 14 mg | 1/11/22 Escitalopram x 2 mg Diazepam x 14 mg | 28/11/22 Escitalopram x 1.61 mg Diazepam x 14 mg | 09/01/23 Escitalopram x 1.30 mg Diazepam x 14 mg | 09/02/23 Escitalopram x 1 mg Diazepam x 14 mg | 09/03/23 Escitalopram x 0.76 mg Diazepam x 14 mg | 09/04/23 Escitalopram x 0.54 mg Diazepam x 14 mg | 08/05/23 Escitalopram x 0.31 mg Diazepam x 14 mg | 06/06/23 Escitalopram x 0.15 mg Diazepam x 14 mg | 04/07/23 Lexapro FREE Diazepam x 14 mg | 10/09/23 Lexapro FREE Diazepam x 13 mg | 02/10/23 Diazepam x 12 mg | 23/10/23 Diazepam x 10 mg | Link to comment Share on other sites More sharing options...
lex1989 Posted June 29, 2022 Share Posted June 29, 2022 On 3/22/2022 at 3:48 AM, curiousnootropics said: Think I reacted badly on CBD oil, sorry to say. Are you on any meds or off? 27/04/21 Escitalopram x 2.5mg Clonazepam 0.375 mg | 14/05/21 Escitalopram x 5mg Clonazepam x 0.5 mg | 30/05/21 Escitalopram x 7.5mg Clonazepam x 0.375 mg | 14/06/21 Escitalopram x 10mg Clonazepam x 0.25 mg | 27/08/21 Escitalopram x 5mg Clonazepam x 0.5 mg | 28/08/21 Escitalopram x 5mg Clonazepam x 0.475 mg | 04/09/21 Escitalopram x 5mg Clonazepam x 0.4 mg | 09/09/21 Escitalopram x 5mg Clonazepam x 0.35 mg | 14/09/21 Escitalopram x 5 mg Clonazepam x 0.3 mg | 14/10/2021 Escitalopram x 4mg Clonazepam x 0.3 mg | 22/10/21 Escitalopram x 4.5mg Clonazepam x 0.3 mg | 19/11/21 Escitalopram x 4mg Clonazepam x 0.3 mg | 29/12/21 Escitalopram x 3.92 mg Clonazepam x 0.3 mg | 2/1/2022 Escitalopram x 3.84 mg Clonazepam x 0.3 mg | 7/1/2022 Escitalopram x 3.76 mg Clonazepam x 0.3 mg | 7/1/2022 Escitalopram x 3.76 mg Clonazepam x 0.3 mg | 17/05/22 Escitalopram x 3.36 mg Diazepam x 14 mg | 12/06/22 Escitalopram x 2.92 mg Diazepam x 14 mg | 01/08/22 Escitalopram x 2.61 mg Diazepam x 14 mg | 29/08/22 Escitalopram x 2.46 mg Diazepam x 14 mg | 1/11/22 Escitalopram x 2 mg Diazepam x 14 mg | 28/11/22 Escitalopram x 1.61 mg Diazepam x 14 mg | 09/01/23 Escitalopram x 1.30 mg Diazepam x 14 mg | 09/02/23 Escitalopram x 1 mg Diazepam x 14 mg | 09/03/23 Escitalopram x 0.76 mg Diazepam x 14 mg | 09/04/23 Escitalopram x 0.54 mg Diazepam x 14 mg | 08/05/23 Escitalopram x 0.31 mg Diazepam x 14 mg | 06/06/23 Escitalopram x 0.15 mg Diazepam x 14 mg | 04/07/23 Lexapro FREE Diazepam x 14 mg | 10/09/23 Lexapro FREE Diazepam x 13 mg | 02/10/23 Diazepam x 12 mg | 23/10/23 Diazepam x 10 mg | Link to comment Share on other sites More sharing options...
Mentor Greatful Posted June 29, 2022 Mentor Share Posted June 29, 2022 @lex1989 Did you end up trying the CBD and vaping like you mentioned the other week? https://www.survivingantidepressants.org/topic/24894-greatful-is-this-withdrawal-or-to-many-med-changes-at-once/ 1995? Prozac, tried several Paxil, Serzone, St John's Wart back to Prozac and Trazodone ct:d Traz Lexapro. Tried to stop Crash in 2015 Kindled Hospitalized, Vybrid, Seroquel, Effexor, Abilify Pristiq, Wellbutrin-- 2016 ended back on Prozac and Lamictal 200mg 5/2020 thru 12/2020 taper from 20mg Prozac down to 3mg. Crashed 12/13/2020 Zoloft 50mg 1/29ct 1/29/2021 Seroquel 50mg ct 2/12/2021 Wellbutrin 75mg. Became hypo manic 2/1 6ct Trazodone 50mg 4/25 25mg 2/5/ 2021 Lamictal 150mg. 2/24 100mg 4/9 75mg 4/21 37.5 2/16/2021 Seroquel 50xr 3/3 100mg 3/17 150mg side effects ct 4/3 2021 Lexapro 5mg 4/14 7.5mg 4/30 10mg 5/10 7.5mg 2021/ 5/16 5mg Lexapro 37.5 Lamictal 25mg trazadone, xanax .0625mg 3x a day Lexapro Taper> Sept/01/2021 4.90mg> Sept/25 4.75mg> Oct/19 4.69mg > Nov/14 4.2mg Jan/30/2022-- Split dosing 2x a day All liquid 4.2mg (2.20mg at 8am & 2mg at 4pm) 2/17 4mg> 2/24 3.8mg slow taper to Aug/12/2022 2.04mg 2023> 2mg, 1.90mg, 1.80mg, 1.70mg, 1.5mg, 1.4mg, 1.3mg 1.2mg, 1.1mg, 1mg, 0.9mg, 0.8mg, 0.7mg 0.65mg, 0.6mg, 0.55mg, 0.5mg, 0.45mg, 0.4mg, 0.35mg, 0.3mg, 0.25,mg, back to once a day dosing 0 .1mg, 0.07mg , 0.05mg 4/1/2024 0 Lamictal taper 4/17/ 2022 25mg, 9/9/ 22 -20mg, 9/25/22- 15mg , 10/20/22- 0 Trazodone..2023.>down to 14mg, 7mg, 6mg July 2023 0 Xanax 0.0625 3 x a day, 2023> 0.042 3x a day Supplements Magnesium glycinate, Omega 3, D3, vitamin c , zinc, NAC Link to comment Share on other sites More sharing options...
Kaervin Posted June 29, 2022 Share Posted June 29, 2022 Curious as well. I tried some cbd gummies when I was having sleep issues. Didn't really feel anything but I only took 20 mgs. 2008: March, Klonopin .5 mg to 1 mg 2009: Dec, CT Klonopin 2010: full year heavy alcohol use 2011: Jan - withdrawals start 2012: Apr- bad wave, start zoloft 50 2014 to 2020: Switch ADs Sertraline 100mgs >Lexapro 20 mgs>Prozac 20 mgs >Lexapro 20 2021: Sertraline 25 mgs 2022: Mar. Cut dose down to 12.5 End of May, starting to crash physically/mentally. Link to comment Share on other sites More sharing options...
ByeByeSSRI Posted September 17, 2022 Share Posted September 17, 2022 Fascinating thread, I read a lot of the 7 pages of posts and wanted to share my experience with cannabis since I'm new here. I've been on paxil for 24 years and I actually credit cannabis as one of the reasons why I started my tapering journey. This is in no way an endorsement for cannabis during withdrawal, simply my personal experience that some might find interesting. I never smoked cannabis, mainly due to the fear of increased anxiety. I had so many panic attacks as a young man (hundreds?) that I had no interest in partaking in a drug that might increase my anxiety. However, when I turned 30, I threw caution to the wind and smoked for the first time (while on paroxetine). Sure enough, I experienced one of the most intense panic attacks I had ever experienced (my fears of cannabis had come true!). However, because of the thc high, I think I was able to "step outside myself" during this panic attack, and view the immense terror I was in from a different perspective. I remember thinking "oh, this is why people call 911 when they smoke!" I felt I was dying and every time I blinked, I felt as though I was time-traveling to later in that night where I was convinced I'd be dead on the bathroom floor. I considered taking a benzo but thankfully decided against it. Eventually, I was able to talk myself down that night. I had become so used to panic attacks growing up, I took a bunch of deep breaths and told myself I'd be fine. Soon, I calmed down and I experienced an immense bliss followed by waves of gratitude, a feeling of connection to the universe, and then deep sleep. For context, at the time I was on either 20mg or 40mg of paroxetine. Over the next few years I experimented with cannabis and I personally found it (again, not an endorsement) to be mind-opening in very helpful ways. It also helped me realize that my paroxetine wasn't "medicine" but very much a drug. For instance, I experienced derealization from smoking one time which helped me connect the dots to the many times I experienced derealization from paroxetine when I was a child. At the time, I never knew it was the paroxetine causing those feelings or what those feelings even were. Growing up, I had a very sheltered childhood and was very fearful of many things. As an adult, I never felt that cannabis "made me anxious" but instead, I felt it was bringing up deep-seated/repressed feelings in me. If anxiety came up, I'd talk with it and ask it why it was there (turns out you can practice this sober as well). For instance, I have a fear of vomiting and have not thrown up since basically before I was put on the pills over 20 years ago. One night I smoked a bit with my wife and instantly felt my stomach turn over and my mouth start to water. I ran to the bathroom, surprised that I might vomit. I tried and tried but only dry-heaved. I was actually over-joyed by this response! I remember yelling to my wife in the other room, "They should give weed to anyone suffering from PTSD! This stuff works!" (Mind you, I was quite high). She was like, "uh, I think they do?" Ha, anyway I digress... I started looking into cannabis-related therapy and found a great teacher named Becca Williams (you can look her up on YT for some free breathing technique videos- no cannabis required). When COVID hit, her class would meet up twice a week to learn about emotions, meditation, and breathing work. On Saturday's classes, we'd smoke a bit (or not, the breathing techniques are powerful on their own) and practice these very active breathing techniques. All sorts of emotions and memories would come up and then after the 15-20 minute session, we'd all journal. These practices also allowed me to cry which I hadn't done since I was a kid. (I remember crying at my wedding, but other than that, I was pretty numb for 24 years) After a year of these meditation classes, I was struck one night (April of 2021) while sitting on my couch with the thought/message: "Chris, it's time to come off the pills." It hit me like a ton of bricks and I started learning everything I could about AD withdrawal. I had tried to taper off paxil twice before, years earlier, and the experiences were horrendous. I had given up and thought I'd be on the pills for life. During my first 16 months of withdrawal, I smoked cannabis every night (flower, not concentrate) and I also drank somewhat regularly, but never heavily. After reading this thread, I'm realizing I must've been very lucky as I realize this isn't the experience of many people posting here. But I wanted to share in case it's helpful or interesting in anyway. More recently, I quit smoking (4 weeks ago, cold turkey) after I felt it was no longer serving me. Mainly because my wife and I are talking about having a baby and we both would never attempt to get pregnant unless completely sober. Quitting cannabis was a walk in the park compared to coming off SSRIs but I do think I'll go low and slow if I ever decide to return to smoking. I learned a lot from my time with MJ and maybe the most important lesson I've learned is that we don't need external substances (street drug or psych drug) on the daily to "feel better." The power is within ourselves. Moreso than cannabis, I really credit meditation, breathing techniques, cold showers, and support groups with helping me in withdrawal. Getting off SSRIs is tough stuff. Ok, I've written enough. I wish for healing and relief for everyone suffering from drug withdrawal. Stay strong- we've got this. 4 1998- 2018 20mg paroxetine (.5mg of Ativan taken "as needed" but never daily or even weekly. Took my last Ativan sometime during 2020) 2018- 4/21 40mg paroxetine 8/20/22 8mg paroxetine 5/30/21 30mg paroxetine 9/8/22 7mg paroxetine 8/4/21 20mg paroxetine Supplements: magnesium, lithium orotate, vitamin D, Lion's Mane, and occasionally L-Theanine) 10/11/21 17.5mg paroxetine (I was a nightly herb smoker from 1/20–8/22. I've also reduced my alcohol from 1-2 drinks a night to ~1 drink/week) 11/8/21 16.2mg paroxetine LINK TO MY INTRO 11/19/21 15mg paroxetine 1/6/22 13.5mg paroxetine 2/20/22 slowly tapered to 10mg paroxetine (rested here for 6 months) 4/1/23 Still slowly tapering. Currently at 4mg Link to comment Share on other sites More sharing options...
JackieDecides Posted September 21, 2022 Share Posted September 21, 2022 On 9/16/2022 at 6:01 PM, ByeByeSSRI said: I started looking into cannabis-related therapy and found a great teacher named Becca Williams (you can look her up on YT for some free breathing technique videos- no cannabis required) one problem with cannabis is how difficult or even impossible it can be to get a low enough dose. especially if you are smoking or vaping. those of us with anxiety know too much can be unpleasant to say the least. a good place to learn a lot about dosage is from Dr. Sulak's website https://healer.com/ he has things for sale but lots and lots of free info. for many people, cannabis IS medicine. Currently taking Ramapril (blood pressure) 5 mg twice a day Omeprazole 10 mg AM and 20 mg PM (the taper has gone nowhere after the first cut) Famotidine once a day (and I still needs tums sometimes) magnesium 200 mg at night as of yesterday 2 fish oil capsules "EPA-DHA 1000" off Lexapro as of 5/2018 - last dose had been 5 mg every other day for a couple years highest dose had been 20 mg at which point I was diagnosed with Bipolar II, which went away when I cut the lexapro down to 15 mg. I spent years on Paxil before Lexapro (can't remember dose), briefly on Effexor and Abilify and others I have forgotten. in fact, when I was diagnoses with BPII I was put on all kinds of things which made me feel so bad I stopped them cold turkey within maybe 3 or 4 weeks, thank goodness. since then I've known these pills were terrible and I weaned down the Lexapro with zero help or support over I'm not sure how many years. Link to comment Share on other sites More sharing options...
conkaia Posted October 11, 2022 Share Posted October 11, 2022 On 12/17/2021 at 2:24 PM, lex1989 said: Lexapro (escitalopram) possible interaction with CBD oil (caution) Lexapro is the brand name for a drug called escitalopram. It is a selective serotonin reuptake inhibitor (SSRI). SSRIs are a class of antidepressant. They’re used to treat major depressive disorder and generalized anxiety disorder. CBD (cannabidiol) is one of the many active compounds found in cannabis. These compounds are called cannabinoids. Unlike its cousin THC (delta-9-tetrahydrocannabinol), CBD does not cause an intoxicating ‘high.’ However, that is not to say that CBD has no psychoactive effects whatsoever. In fact, it has become well known for its supposed anti-anxiety and antidepressant properties. Nowadays, more people are turning to CBD to relieve the symptoms of anxiety and depression. However, scientists are still trying to ascertain exactly how the cannabinoid works for these conditions. This post it is meant to prevent and explain a possible interaction with this 2 drugs, although CBD can be recognized as a supplement or a herb also. The following enzymes metabolize Lexapro: CYP3A4 CYP2D6 CYP2C19 The CYP450 pathway also metabolizes CBD in the liver. The specific enzymes responsible for breaking down CBD are: CYP3A4 CYP2C9 CYP2C19 As it turns out, CBD inhibits the enzymes CYP3A4 and CYP2C6. As you can see, Lexapro and CBD share many of the same enzymatic pathways and, therefore, have a strong chance of interacting. So the downside is that taking CBD alongside Lexapro may increase the amount of antidepressants in the body. One might assume this is a positive thing, but it significantly increases the risk of harmful side effects if taken together. It is recommended that anyone wanting to try CBD for depression / anxiety should stop taking their medication first and then make the switch. However, it is essential that one does this gradually, carefully like we all know from all the information we have on here. Combining this two can outcome the risk or severity of serotonin syndrome, also noted the fact that combining any A/D with CBD oil can increase the risk or severity of adverse effects. In conclusion, both Lexapro and CBD oil are popular remedies for depression and anxiety. However, taking the two together may cause a drug interaction as they are both metabolized by the same enzymes in the liver. Relevant links : https://wayofleaf.com/cbd/101/does-cbd-oil-interact-with-lexapro https://go.drugbank.com/drugs/DB01175 Wow, I did NOT realise this. I've tried CBD oil but its did absolutely nothing for me; this may well explain why. Thanks for the post, I'll follow this thread with interest. Guess I won't use anymore CBD until such times as I can get off this poison. Although I wonder if it would be helpful to supplement when reducing dose to minimise withdrawal, does anyone have any thoughts? August 2004: Citalopram 20mg for "postnatal anxiety". May-Sept 2011: Adverse reaction to the contraceptive pill, causing severe anxiety and panic. Was switched from 7 years on Citalopram to Lofepramine briefly, then Mirtazapine 30mg. Was an anxious, depressed, suicidal wreck and got misdiagnosed with GAD by a psychiatrist. I now realise my symptoms were all medication related, as opposed to so-called psychiatric diagnosis. October 2011: Pregabalin 450mg and propranolol 40mg TID added by psychiatrist. Feb 2013: Tapered off pregabalin 450mg; stopped propranolol. July 2013: Switched from Mirtazapine 30mg to Cipralex 10mg in a two-week cross titration, which caused horrific withdrawal symptoms lasting months. April 2015: Increased to 15mg Cipralex. 2017: Was treated by a clinical psychologist for medication-related trauma and slowly tapered down to 2mg Cipralex over the next four years. December 2021: Switched from Cipralex tablets to drops to facilitate further tapering; this caused withdrawal reaction lasting approx 6 weeks. May 2022: Experienced severe withdrawal reaction after inadvertently taking expired drops. 3rd June 2022: Reinstated 2mg Cipralex drops. Stabilisation hindered by drinking alcohol socially; didn't realise impact of this. Nil alcohol since September 2022. Supplements: Cycling Magnesium, Omega 3, Evening Primrose, Vitamin D3, Vitamin C, Vitamin B Complex, Zinc, Ashwagandha, Sage. Had been taking these prior to withdrawal incident. Feb 2023: Relatively stable and aiming to hold on 2mg Cipralex and with a view to tapering down in 2024. Tapered off Ashwagandha. Link to comment Share on other sites More sharing options...
catmama Posted October 11, 2022 Share Posted October 11, 2022 3 hours ago, conkaia said: Wow, I did NOT realise this. I've tried CBD oil but its did absolutely nothing for me; this may well explain why. Thanks for the post, I'll follow this thread with interest. Guess I won't use anymore CBD until such times as I can get off this poison. Although I wonder if it would be helpful to supplement when reducing dose to minimise withdrawal, does anyone have any thoughts? I have tried using a high quality full-spectrum CBD oil to help with WD insomnia. I found that it doesn't really help much, and the following days my dizziness/lightheadedness seems to be worse. So I stopped using it. Of course YMMV. 1 • 2013-2015: paroxetine, with brief switch to sertraline, and brief combo with bupropion • 2015: got off all antidepressant meds for approx 9-12 months, felt great • 2015: fluoxetine, bad side effects, quit after two weeks • 2015: escitalopram 15mg/day • Summer 2019: attempted fast taper off escitalopram, reinstated to 15mg/day dose after six weeks • October 16, 2020: begin taper off escitalopram at rate of 1mg per 1 week (sometimes per 2 weeks) using 1mg/ml liquid from pharmacy • Jan 22, 2021: down to 3mg and holding due to worsening of WD symptoms • Feb 4, 2021: updose to 4mg holding • Feb 2021: tapering at 10% every 28 days • Jul 2021: begin using microtaper of 2.5% per week • Feb 2022: down to 1.43mg and experiencing worsening WD symptoms, updose to 1.45mg and holding • Mar 2022: resume microtaper schedule, lowest dose: 1.34 mg • Mar 2022: extended hold at 1.36 mg •Jul 2022: resume 10% taper • Apr 2-Jun 21, 2023 extended hold at 0.5mg • Jun 9, 2023 massive life stress situation triggered WD wave, Jun 15-16 took 5mg dose, Jun 17-21 back to 0.5mg dose • Jun 22 small updose to 0.58mg • Jul 1-2 tried 2.5mg, suffered adverse affects (anxiety, can’t eat, palpitations, electric jolts in chest) • Jul 1, 2023 - Jan 3, 2024 long hold at 1mg, slowly stabilizing after crash • Jan 4 resume taper 0.98mg Jan 11 0.95mg Supplements: vitamin D3 with K2, vitamin C, iron, magnesium glycinate, EPA/DHA essentials fish oil, melatonin(as needed) Other prescription meds: levothyroxine 75 mcg (for hypothyroidism), lorazepam 0.25 to 0.5mg (as needed, which is almost never), zofran 2 to 4mg (as needed) Link to comment Share on other sites More sharing options...
Ventus Posted October 11, 2022 Share Posted October 11, 2022 I have tried cbd and it doesn't do much. But I also don't really have many day time symptoms. CBD does nothing for my sleep. THC is the most effective sleep aid during my periods of insomnia but I am afraid to use it long term in case of tolerance. I might go back to it soon because the insomnia is not letting up this time do to my mistake. ???? To early April 2021: citalopram 20mg. This was a about 12+years April 2021: stopped taking citalopram 6/10/2021 to 6/11/2021: started taking buspirone for anxiety . Got ringing in the ears and insomnia so I stopped 6/16/2021 reinstatement of citalopram at 10mg 8/12/2021: 4.5ml/9mg citalopram 10/11/21 4ml 11/15/21 3.5ml 12/28/2021: 3ml/6mg 1/28/2022 2.5ml/5mg 2mL/4mg 3/6/2022 1.5ml/3mg 4/12/2022 5/31/2022 1ml/2mg 7/31/2022 .5ml/1mg 9/3/2022: .4ml/.8mg citalopram. after a few days got some severe withdrawal so .45ml/.9mg 9/8/2022 10/6/2022 1mg again .45ml/.9mg 12/9/2022 Link to comment Share on other sites More sharing options...
SouthernFreeze Posted October 11, 2022 Share Posted October 11, 2022 5 hours ago, Ventus said: I have tried cbd and it doesn't do much. But I also don't really have many day time symptoms. CBD does nothing for my sleep. THC is the most effective sleep aid during my periods of insomnia but I am afraid to use it long term in case of tolerance. I might go back to it soon because the insomnia is not letting up this time do to my mistake. I'm not condoning it, but it did help me with a drop. 10 years on various anti-depressants 5 years Effexor xr tappered of 150mg in 6 months nothing for two weeks Reinstated 15 beads for 50 days Tappered off then clean 2-3months gradually went back up to 13 mg 3 years bridged fluoxetine 10mg 2 week tapper 1 year clean reinstated 5ml dispersed fluroxatine for 6months Link to comment Share on other sites More sharing options...
Ventus Posted October 11, 2022 Share Posted October 11, 2022 It's the only reason I am functioning right now. I am taking a few weeks break but that means dealing with little sleep. I hate this wave and wish it would end. ???? To early April 2021: citalopram 20mg. This was a about 12+years April 2021: stopped taking citalopram 6/10/2021 to 6/11/2021: started taking buspirone for anxiety . Got ringing in the ears and insomnia so I stopped 6/16/2021 reinstatement of citalopram at 10mg 8/12/2021: 4.5ml/9mg citalopram 10/11/21 4ml 11/15/21 3.5ml 12/28/2021: 3ml/6mg 1/28/2022 2.5ml/5mg 2mL/4mg 3/6/2022 1.5ml/3mg 4/12/2022 5/31/2022 1ml/2mg 7/31/2022 .5ml/1mg 9/3/2022: .4ml/.8mg citalopram. after a few days got some severe withdrawal so .45ml/.9mg 9/8/2022 10/6/2022 1mg again .45ml/.9mg 12/9/2022 Link to comment Share on other sites More sharing options...
conkaia Posted October 17, 2022 Share Posted October 17, 2022 On 10/11/2022 at 5:42 PM, Ventus said: I have tried cbd and it doesn't do much. But I also don't really have many day time symptoms. CBD does nothing for my sleep. THC is the most effective sleep aid during my periods of insomnia but I am afraid to use it long term in case of tolerance. I might go back to it soon because the insomnia is not letting up this time do to my mistake. I'm literally too scared to take anything psychoactive until I heal! August 2004: Citalopram 20mg for "postnatal anxiety". May-Sept 2011: Adverse reaction to the contraceptive pill, causing severe anxiety and panic. Was switched from 7 years on Citalopram to Lofepramine briefly, then Mirtazapine 30mg. Was an anxious, depressed, suicidal wreck and got misdiagnosed with GAD by a psychiatrist. I now realise my symptoms were all medication related, as opposed to so-called psychiatric diagnosis. October 2011: Pregabalin 450mg and propranolol 40mg TID added by psychiatrist. Feb 2013: Tapered off pregabalin 450mg; stopped propranolol. July 2013: Switched from Mirtazapine 30mg to Cipralex 10mg in a two-week cross titration, which caused horrific withdrawal symptoms lasting months. April 2015: Increased to 15mg Cipralex. 2017: Was treated by a clinical psychologist for medication-related trauma and slowly tapered down to 2mg Cipralex over the next four years. December 2021: Switched from Cipralex tablets to drops to facilitate further tapering; this caused withdrawal reaction lasting approx 6 weeks. May 2022: Experienced severe withdrawal reaction after inadvertently taking expired drops. 3rd June 2022: Reinstated 2mg Cipralex drops. Stabilisation hindered by drinking alcohol socially; didn't realise impact of this. Nil alcohol since September 2022. Supplements: Cycling Magnesium, Omega 3, Evening Primrose, Vitamin D3, Vitamin C, Vitamin B Complex, Zinc, Ashwagandha, Sage. Had been taking these prior to withdrawal incident. Feb 2023: Relatively stable and aiming to hold on 2mg Cipralex and with a view to tapering down in 2024. Tapered off Ashwagandha. Link to comment Share on other sites More sharing options...
Ventus Posted October 17, 2022 Share Posted October 17, 2022 I do not blame you at all. I am not really sensitive to stuff so I can but honestly I don't like how they make me feel. If thc wasn't the most effective easiest to get sleep aid I wouldn't touch it. ???? To early April 2021: citalopram 20mg. This was a about 12+years April 2021: stopped taking citalopram 6/10/2021 to 6/11/2021: started taking buspirone for anxiety . Got ringing in the ears and insomnia so I stopped 6/16/2021 reinstatement of citalopram at 10mg 8/12/2021: 4.5ml/9mg citalopram 10/11/21 4ml 11/15/21 3.5ml 12/28/2021: 3ml/6mg 1/28/2022 2.5ml/5mg 2mL/4mg 3/6/2022 1.5ml/3mg 4/12/2022 5/31/2022 1ml/2mg 7/31/2022 .5ml/1mg 9/3/2022: .4ml/.8mg citalopram. after a few days got some severe withdrawal so .45ml/.9mg 9/8/2022 10/6/2022 1mg again .45ml/.9mg 12/9/2022 Link to comment Share on other sites More sharing options...
itiscomplicated Posted October 22, 2022 Share Posted October 22, 2022 I suspect that cannabis use (THC and CBD) played some part in the weirdness I've experienced both on psych meds and after stopping cold turkey. For example: one day about four months after stopping all meds (I was still using cannabis, though), I put some CBD oil on my lips, and suddenly felt zaps surging down my body, left to right. It was extremely alarming, and I had no idea what was going on. 2003 - Ritalin, Vyvanse 2004 - Wellbutrin 2006 - Temazepam, possibly an antidepressant 2006 to present - testosterone cypionate, 100mg every 10 days 2008 - Clonazepam 2011 - Chantix, Adderall, Vyvanse, Lamictal 200mg 2012 - Lamictal 200mg, Wellbutrin 2013 - Lamictal 200mg, others 2014 - Lamictal 200mg, Latuda, Prozac, Clonazepam, Gabapentin, others 2015 on - Lamictal 200mg, Sapphris, Vraylar, Clonazepam, Lithium, Wellbutrin, Desipramine, Effexor, Adderall, Seroquel, Depakote, others, ECT 2018 to 2022 - medical cannabis for headaches 2022 (ended in March) - Lamictal 200mg, Wellbutrin XL 300mg, Adderall 15mg, Lexapro 5mg, Xanax 0.5mg (prn) Link to comment Share on other sites More sharing options...
Thorin Posted November 25, 2022 Share Posted November 25, 2022 So I abused cannabis as a young teenager and ended up having a horrible experience (not just cannabis if I’m honest). So I was very wary of going near it again despite being in my early 40s. At 41 I was prescribed CBD oil and felt it often helped me with anxiety. Better than psych meds (not as well as Xanax but it had none of the hooks that Xanax has). I eventually tried a very low dose CBD:THC oil (10mg THC per ml). I’ve found that no matter the symptom, anxiety, trauma issue a low dose of THC will allow me to just sit with the feeling/experience, which in turn allows me to start processing it. I hope I don’t have to take it forever but for the moment I feel that it’s benefitting me. 2 Age 16 (1995 - 2000) -Paroxetine Age 21 (2000-2004) - Effexor 37.5mg Age 24 (2004-2012) - Lexapro (70mg), Xanax minimum 2mg Xanax a day About 32 (2012-2017?) - Every mood stabiliser under the sun (not at the same time) and minimum 2mg Xanax a day; occasional amisulpride About 35 (2017-current) - Lurasidone 80 mg, quickly titrated down to 40mg, Pristiq (50 mg), minimum of 2mg Xanax a day About 41 (2020) Switched from Xanax to clonazepam and started tapering at 0.125 mg each reduction, tapered off Pristiq with a cross taper at the end, low dose of dextroamphetamine. Age 42 (2021) Tried to taper off Lurasidone three times. Quick taper from 40mg to 0 mg over a couple of months the first time. Reinstated at 20mg. Tried twice more to taper from 20 mg to 0 mg dropping by 5 mg each reduction (about every 2 weeks). Age 42-43 (April 2022) 20mg-18mg; May 18mg-16mg; June 16-14mg; September 14-12mg; September 12-14mg reinstated. February 2023 - hiccup with brand change, Back to Apotek brand and switch to homemade suspension. Age 44 (August 2023 -restarted clonazepam taper). Start dose 0.375mg. 1/9/2023 - 0.365mg; 1/10/2023 - 0.324mg; 1/11/2023 - 0.264mg; 1/12/2023 - 0.25 mg (holding); 1/2/2024 - 0.232mg; 1/3/2024 - 0.221mg; 1/4/2024 - 0.205mg; Health regimen: walks, hot/cold showers, ice baths, breathwork, mostly healthy diet, therapy...... Open to ideas! Supplements: Milk Kefir, Mag, Omega 3, CBD/THC. Link to comment Share on other sites More sharing options...
Moderator hayduke Posted November 29, 2022 Moderator Share Posted November 29, 2022 I think the CBD vs THC ratio is one of the major things to concentrate on with this natural medicine. 1 I am not a health professional - your actions are your own. Please do not seek tapering support via private message - "Any reason to hold is a good one" My taper visualised as a graph | My intro thread Backdrop: 2003 10mg olanzapine | 2004 2-3mg risperidone | end 2014 3wks aripiprazole 2015: olanzapine 10 -> 7½ -> 6⅔ -> 5mg by crude pill cutter 2018: Mar 5.00mg -> water titrated taper -> Aug2.5mg tablet and hold Jan 2019 2.50mg water titration -> Jan 2020 1.214 -> Jan 2021 0.44 -> 2 Oct 0.205 ->3 Oct ZERO🥂 Jun 2023 💉150mg paliperidone "loading" depot shot, 100mg 1wk after Jul 100mg Aug-Dec 75mg/4wks Jul 2023 2.50mg aripiprazole/day attempt to lower prolactin^ Jan-Feb 2024 cross taper off shots to 1mg risperidone Ask not what you can do for your country, but what your country did to you" -- KMFDM Link to comment Share on other sites More sharing options...
Moderator hayduke Posted November 29, 2022 Moderator Share Posted November 29, 2022 https://www.youtube.com/watch?v=T2cAFRAX3Gs I am not a health professional - your actions are your own. Please do not seek tapering support via private message - "Any reason to hold is a good one" My taper visualised as a graph | My intro thread Backdrop: 2003 10mg olanzapine | 2004 2-3mg risperidone | end 2014 3wks aripiprazole 2015: olanzapine 10 -> 7½ -> 6⅔ -> 5mg by crude pill cutter 2018: Mar 5.00mg -> water titrated taper -> Aug2.5mg tablet and hold Jan 2019 2.50mg water titration -> Jan 2020 1.214 -> Jan 2021 0.44 -> 2 Oct 0.205 ->3 Oct ZERO🥂 Jun 2023 💉150mg paliperidone "loading" depot shot, 100mg 1wk after Jul 100mg Aug-Dec 75mg/4wks Jul 2023 2.50mg aripiprazole/day attempt to lower prolactin^ Jan-Feb 2024 cross taper off shots to 1mg risperidone Ask not what you can do for your country, but what your country did to you" -- KMFDM Link to comment Share on other sites More sharing options...
Ventus Posted November 29, 2022 Share Posted November 29, 2022 Depends on what you are using it for so yes. Personally I get editables that are either thc or cbd alone. So not much of a ratio. That being said I haven't needed any in weeks! 1 ???? To early April 2021: citalopram 20mg. This was a about 12+years April 2021: stopped taking citalopram 6/10/2021 to 6/11/2021: started taking buspirone for anxiety . Got ringing in the ears and insomnia so I stopped 6/16/2021 reinstatement of citalopram at 10mg 8/12/2021: 4.5ml/9mg citalopram 10/11/21 4ml 11/15/21 3.5ml 12/28/2021: 3ml/6mg 1/28/2022 2.5ml/5mg 2mL/4mg 3/6/2022 1.5ml/3mg 4/12/2022 5/31/2022 1ml/2mg 7/31/2022 .5ml/1mg 9/3/2022: .4ml/.8mg citalopram. after a few days got some severe withdrawal so .45ml/.9mg 9/8/2022 10/6/2022 1mg again .45ml/.9mg 12/9/2022 Link to comment Share on other sites More sharing options...
Moderator hayduke Posted November 29, 2022 Moderator Share Posted November 29, 2022 Since I started yoga a bit over a decade ago, I have come to find that a much more reliable way to calm the CNS and release somatic tensions. Plus you don't get muddle headed. I am not a health professional - your actions are your own. Please do not seek tapering support via private message - "Any reason to hold is a good one" My taper visualised as a graph | My intro thread Backdrop: 2003 10mg olanzapine | 2004 2-3mg risperidone | end 2014 3wks aripiprazole 2015: olanzapine 10 -> 7½ -> 6⅔ -> 5mg by crude pill cutter 2018: Mar 5.00mg -> water titrated taper -> Aug2.5mg tablet and hold Jan 2019 2.50mg water titration -> Jan 2020 1.214 -> Jan 2021 0.44 -> 2 Oct 0.205 ->3 Oct ZERO🥂 Jun 2023 💉150mg paliperidone "loading" depot shot, 100mg 1wk after Jul 100mg Aug-Dec 75mg/4wks Jul 2023 2.50mg aripiprazole/day attempt to lower prolactin^ Jan-Feb 2024 cross taper off shots to 1mg risperidone Ask not what you can do for your country, but what your country did to you" -- KMFDM Link to comment Share on other sites More sharing options...
Tridentata Posted January 7, 2023 Share Posted January 7, 2023 Well, that's an experiment I won't try again: ate a full-spectrum CBD gummy last night between dinner and bed, 25 mg CBD + 2 mg THC, supposedly below the psychoactive threshold. Indeed I felt little effect from it while awake, but I'm assuming it was the reason for one of the worst nights of sleep I've had during withdrawal off amitriptyline (from 10 mg, currently at 2.5). I can't be certain it was the CBD/THC interacting with ami or with the WD symptoms, but before I was on ami I did use full-spectrum sublingual CBD without problems. I haven't had a substantial amount of THC for many years so I don't know how it would have affected me before I went on ami last year. Given how disruptive this was, I imagine I should treat the episode as a destabilization and hold at my current dose for a couple of weeks? I was about ready to taper another 10%, alas. Amitriptyline: prescribed 10 mg/day in mid-August 2022 Began fairly quick taper 18 October 2022 to 3 mg by 9 November (no withdrawal symptoms) Reinstated at 10 mg on 9 November leading to some serious sleep disturbance 10–17 November, tried 8 or 9 mg 18 November, 10 mg 19–22 November, 3.5 mg after advice to drop back to taper level 23 November – 14 Dec., 3 mg 15–22 Dec., 2.7 mg 23 Dec. 2022 to 3/15/2023, ranged from 2.5 mg up to 3 mg w/partial reinstatement after bad crash provoked by CBD/THC gummy, then slowly back down to 2.5 with long hold in March from 15 March 2023, continued slow taper (Brassmonkey slide, 2.5% week + 2 week hold every 4 weeks) to 1.2 mg as of 1/1/24. Increased tapering speed to 20% in 6 weeks, probably bad idea. Other medications: albuterol inhaler as needed, acetaminophen as needed Supplements: daily multivitamin, magnesium glycinate 400 mg/day PRN, probiotics Caffeine: Max 1 cup coffee/day or 2 cups of tea Link to comment Share on other sites More sharing options...
Ryder Posted January 8, 2023 Share Posted January 8, 2023 Yes, most likely. 👌👌 2008-2012: Cymbalta, Zyprexa, Valium (5 days supply), 2012 - Seroquel x 4 weeks C/T. 2014 - Seroquel x 2 Weeks C/T. Crossed to Risperidone 3mg for 6months until December. 2014 - Stopped Risperidone. Xfer > Anti-Depressant 200mg Zoloft and 6mg Clonazepam. 2018 - 150mg Clomipromine changed Anti-depressant. Tapered Benzo to 1mg Clonazepam. 2019 - xfer to 20mg Diazepam. Currently: Anafranil: 75mg. 17th Dec 2022 70mg. 27th Dec 22: 75mg, 14 January 23': 70mg. 16-26th January: 50mg (too fast drop no sleep). Jan 28th 2023: 70mg. 20 Feb 2023: 65mg. 11/06: 60mg 9/08: 55mg 15/08/23 : 50mg 3/03/2024: 60mg (Updose) Diazepam (V): 25th Oct 2019' 20mg. 22 Dec 19' 19mg. 04 Apr 2020' 18mg, 30 September 20' 17.5mg , 13 Nov 2020' 17mg. 01 January 2021: 16mg, 13th Aug 21' 15mg. 1st Nov' 2021 14.5mg. 1st Dec' 2021 14mg. 13 January 2022: 13.5mg, 11 Feb: 13mg. 11 April 22' 12.5mg, 12 May 22': 12mg, 6th September 2022: 11mg Valium. 9th October: 10.5mg, 25th Oct 10mg. 12 March 23: 9.5mg 2 April: 9.25mg 23 April: 9mg 12/05: 8.75 26/05: 8.5 12/09: 8.25 21/09: 8.5. 3/10: 8.25 17/10: 8mg 20th Nov Brassmonkey: (7.9.,7.8, 7.75) 5 Feb: 7.25mg. 23 Feb: 7mg *. Have tried to go at faster rate than 0.5mg but is currently too fast. Link to comment Share on other sites More sharing options...
Thorin Posted January 13, 2023 Share Posted January 13, 2023 On 11/29/2022 at 1:27 PM, hayduke said: I think the CBD vs THC ratio is one of the major things to concentrate on with this natural medicine. You probably know already but THC is considered ‘propsychotic’ and CBD is considered ‘antipsychotic). The the strains that have been selectively bred for high THC content that cause problems at times. Originally THC would have been much lower and CBD higher and the medicine would have been a little ‘healthier’ if that makes sense. Age 16 (1995 - 2000) -Paroxetine Age 21 (2000-2004) - Effexor 37.5mg Age 24 (2004-2012) - Lexapro (70mg), Xanax minimum 2mg Xanax a day About 32 (2012-2017?) - Every mood stabiliser under the sun (not at the same time) and minimum 2mg Xanax a day; occasional amisulpride About 35 (2017-current) - Lurasidone 80 mg, quickly titrated down to 40mg, Pristiq (50 mg), minimum of 2mg Xanax a day About 41 (2020) Switched from Xanax to clonazepam and started tapering at 0.125 mg each reduction, tapered off Pristiq with a cross taper at the end, low dose of dextroamphetamine. Age 42 (2021) Tried to taper off Lurasidone three times. Quick taper from 40mg to 0 mg over a couple of months the first time. Reinstated at 20mg. Tried twice more to taper from 20 mg to 0 mg dropping by 5 mg each reduction (about every 2 weeks). Age 42-43 (April 2022) 20mg-18mg; May 18mg-16mg; June 16-14mg; September 14-12mg; September 12-14mg reinstated. February 2023 - hiccup with brand change, Back to Apotek brand and switch to homemade suspension. Age 44 (August 2023 -restarted clonazepam taper). Start dose 0.375mg. 1/9/2023 - 0.365mg; 1/10/2023 - 0.324mg; 1/11/2023 - 0.264mg; 1/12/2023 - 0.25 mg (holding); 1/2/2024 - 0.232mg; 1/3/2024 - 0.221mg; 1/4/2024 - 0.205mg; Health regimen: walks, hot/cold showers, ice baths, breathwork, mostly healthy diet, therapy...... Open to ideas! Supplements: Milk Kefir, Mag, Omega 3, CBD/THC. Link to comment Share on other sites More sharing options...
Moderator hayduke Posted January 21, 2023 Moderator Share Posted January 21, 2023 On 1/13/2023 at 7:32 PM, Thorin said: You probably know already but THC is considered ‘propsychotic’ and CBD is considered ‘antipsychotic). The the strains that have been selectively bred for high THC content that cause problems at times. Originally THC would have been much lower and CBD higher and the medicine would have been a little ‘healthier’ if that makes sense. Pretty much. How ironic that stale dogma in Australia interferes with responsible usage. Specifically, potentially troublesome high THC hydro is ubiquitous, while mellow high CBD strains are rare and coveted. Except in the A.C.T, where politicians can indulge scot free to their hearts' content. John Birmingham wrote a social history about cannabis some years ago, IIRC that was where I read that a great many "conservative" Australian politicians love getting baked. Hypocrites. I really applaud Canada's federal legalisation of this plant. Bill Hicks had a great sketch about this. "Making a plant illegal is saying God made a mistake" etc etc. I am not a health professional - your actions are your own. Please do not seek tapering support via private message - "Any reason to hold is a good one" My taper visualised as a graph | My intro thread Backdrop: 2003 10mg olanzapine | 2004 2-3mg risperidone | end 2014 3wks aripiprazole 2015: olanzapine 10 -> 7½ -> 6⅔ -> 5mg by crude pill cutter 2018: Mar 5.00mg -> water titrated taper -> Aug2.5mg tablet and hold Jan 2019 2.50mg water titration -> Jan 2020 1.214 -> Jan 2021 0.44 -> 2 Oct 0.205 ->3 Oct ZERO🥂 Jun 2023 💉150mg paliperidone "loading" depot shot, 100mg 1wk after Jul 100mg Aug-Dec 75mg/4wks Jul 2023 2.50mg aripiprazole/day attempt to lower prolactin^ Jan-Feb 2024 cross taper off shots to 1mg risperidone Ask not what you can do for your country, but what your country did to you" -- KMFDM Link to comment Share on other sites More sharing options...
Thorin Posted January 22, 2023 Share Posted January 22, 2023 10 hours ago, hayduke said: Pretty much. How ironic that stale dogma in Australia interferes with responsible usage. Specifically, potentially troublesome high THC hydro is ubiquitous, while mellow high CBD strains are rare and coveted. Except in the A.C.T, where politicians can indulge scot free to their hearts' content. John Birmingham wrote a social history about cannabis some years ago, IIRC that was where I read that a great many "conservative" Australian politicians love getting baked. Hypocrites. I really applaud Canada's federal legalisation of this plant. Bill Hicks had a great sketch about this. "Making a plant illegal is saying God made a mistake" etc etc. Big fan of Bill Hicks here. Yes it’s hilarious how all the politicians and public servants can do what they want but not the rest of Australia. You can be prescribed cannabis, but outside of ACT and TAS if you have THC in your system and are driving you can lose your license. Cannabis stays in your system quite some time if you’re a regular user. I could use it a week ago and be caught a week later with it in my system, even though it’s legally prescribed. But I could take Xanax or Oxycodone today and drive immediately after with no repercussions. Disgusting. Age 16 (1995 - 2000) -Paroxetine Age 21 (2000-2004) - Effexor 37.5mg Age 24 (2004-2012) - Lexapro (70mg), Xanax minimum 2mg Xanax a day About 32 (2012-2017?) - Every mood stabiliser under the sun (not at the same time) and minimum 2mg Xanax a day; occasional amisulpride About 35 (2017-current) - Lurasidone 80 mg, quickly titrated down to 40mg, Pristiq (50 mg), minimum of 2mg Xanax a day About 41 (2020) Switched from Xanax to clonazepam and started tapering at 0.125 mg each reduction, tapered off Pristiq with a cross taper at the end, low dose of dextroamphetamine. Age 42 (2021) Tried to taper off Lurasidone three times. Quick taper from 40mg to 0 mg over a couple of months the first time. Reinstated at 20mg. Tried twice more to taper from 20 mg to 0 mg dropping by 5 mg each reduction (about every 2 weeks). Age 42-43 (April 2022) 20mg-18mg; May 18mg-16mg; June 16-14mg; September 14-12mg; September 12-14mg reinstated. February 2023 - hiccup with brand change, Back to Apotek brand and switch to homemade suspension. Age 44 (August 2023 -restarted clonazepam taper). Start dose 0.375mg. 1/9/2023 - 0.365mg; 1/10/2023 - 0.324mg; 1/11/2023 - 0.264mg; 1/12/2023 - 0.25 mg (holding); 1/2/2024 - 0.232mg; 1/3/2024 - 0.221mg; 1/4/2024 - 0.205mg; Health regimen: walks, hot/cold showers, ice baths, breathwork, mostly healthy diet, therapy...... Open to ideas! Supplements: Milk Kefir, Mag, Omega 3, CBD/THC. Link to comment Share on other sites More sharing options...
Tridentata Posted February 19, 2023 Share Posted February 19, 2023 This might help explain why taking a full-spectrum CBD gummy with 2g THC disrupted my amitriptyline withdrawal taper pretty badly. https://www.drugs.com/news/cbd-could-worsen-thc-brownies-other-products-110784.html Amitriptyline: prescribed 10 mg/day in mid-August 2022 Began fairly quick taper 18 October 2022 to 3 mg by 9 November (no withdrawal symptoms) Reinstated at 10 mg on 9 November leading to some serious sleep disturbance 10–17 November, tried 8 or 9 mg 18 November, 10 mg 19–22 November, 3.5 mg after advice to drop back to taper level 23 November – 14 Dec., 3 mg 15–22 Dec., 2.7 mg 23 Dec. 2022 to 3/15/2023, ranged from 2.5 mg up to 3 mg w/partial reinstatement after bad crash provoked by CBD/THC gummy, then slowly back down to 2.5 with long hold in March from 15 March 2023, continued slow taper (Brassmonkey slide, 2.5% week + 2 week hold every 4 weeks) to 1.2 mg as of 1/1/24. Increased tapering speed to 20% in 6 weeks, probably bad idea. Other medications: albuterol inhaler as needed, acetaminophen as needed Supplements: daily multivitamin, magnesium glycinate 400 mg/day PRN, probiotics Caffeine: Max 1 cup coffee/day or 2 cups of tea Link to comment Share on other sites More sharing options...
HughesEddie Posted April 4, 2023 Share Posted April 4, 2023 Hello all, I’m just after a few extra opinions and peoples experiences. I started smoking cannabis when I was around 18. I smoked it, and quite frankly, really enjoyed smoking on a daily habitual basis up until when I (stupidly) started taking mirtazapine at the age of 31. A few weeks into taking mirt, I found that when I smoked it, that I had horrendous feelings that are hard to explain, which I can only describe as anxiety, which I don’t even know if this is the right term to describe how i feel. I am just wondering if anybody else had similar experiences? It got so uncomfortable when smoking where it got to the point that I ended up quitting smoking cannabis around 5 months or so into being on the mirt. This was something that before taking mirt, i could have never imagined as I was quite badly addicted to smoking regularly, and would hate not being able to smoke. So to see such a turnaround, from a regular (daily) smoker for around 13 years, to suddenly not being able to handle a few puffs, seemed very odd and quite frankly, strange to me. So I can’t help but think it is the mirtazapine that made the difference. Although stopping smoking is of course a good thing, in all honesty I do miss it as it was my way of unwinding and having a chill out. I no longer take mirtazapine, after tapering admittedly too quickly from 30 mg to completely stopping, over the course of around 2 and a half months (as best as I can remember). I haven’t taken any mirtazapine since June 2022 so have been in what I believe to be withdrawal for around the last 9 months and a week or 2. But still at this point I can’t handle smoking cannabis the odd time I do try a few puffs. Is this normal? And although it seems a little wrong to ask this question, but being as legalisation is becoming more and more common around the world, will I ever be able to enjoy a smoke with my friends again, and feel the way I used to (just normally high) and not feel like I’m in some strange trippy world? Thanks for reading, and I look forward to what you guys may have to say on this matter. Link to comment Share on other sites More sharing options...
ByeByeSSRI Posted April 4, 2023 Share Posted April 4, 2023 Hey Eddie- Thanks for sharing. I'm no expert but I would think both starting the mirtazapine and coming off of it really shook up your system. Adding cannabis (even though you were used to smoking) obviously didn't mix well. Good for you for listening to your body. Bravo for pausing the cannabis bc it was making things worse as well as tapering off of the mirtazapine. Since you're only 9 months off of the meds after a fast taper, I'd say to just give it time. Your body should eventually heal and readjust. Will cannabis effect you in a positive way once again? Who knows. You could always try again later but also know that life is good without cannabis as well. I've been working on quitting cannabis myself. I was on paxil for decades and THEN introduced cannabis. I never smoked until I was 30 and I had been on paxil since I was 10. I had very positive experiences with cannabis for a number of years and I even credit cannabis with helping me to "reconnect" with myself and realize that I had to get off paxil. I started tapering 2 years ago and I'm now almost completely off. I've been smoking way less during tapering but at the start of my taper, cannabis really helped withdrawal symptoms. However now, having just a few hits of a joint just doesn't sit quite right to me. Lately I've found I feel better without cannabis. I have nothing against the plant but I also respect the fact that it seems to have a mind of its own. Perhaps it'll be a helpful tool for me in the future but for the time being, my relationship with cannabis is certainly "on hold." 1998- 2018 20mg paroxetine (.5mg of Ativan taken "as needed" but never daily or even weekly. Took my last Ativan sometime during 2020) 2018- 4/21 40mg paroxetine 8/20/22 8mg paroxetine 5/30/21 30mg paroxetine 9/8/22 7mg paroxetine 8/4/21 20mg paroxetine Supplements: magnesium, lithium orotate, vitamin D, Lion's Mane, and occasionally L-Theanine) 10/11/21 17.5mg paroxetine (I was a nightly herb smoker from 1/20–8/22. I've also reduced my alcohol from 1-2 drinks a night to ~1 drink/week) 11/8/21 16.2mg paroxetine LINK TO MY INTRO 11/19/21 15mg paroxetine 1/6/22 13.5mg paroxetine 2/20/22 slowly tapered to 10mg paroxetine (rested here for 6 months) 4/1/23 Still slowly tapering. Currently at 4mg Link to comment Share on other sites More sharing options...
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