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fleurdelice: Lexapro and Abilify withdrawal - excessive sweating


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Hi everyone, I'm a 31 year old woman currently tapering off both Lexapro and Abilify and I'm dealing with some pretty unpleasant withdrawal symptoms so far. I can handle the mental fog and increased anxiety but the physical side effects of withdrawal- specifically heat intolerance and uncontrollable craniofacial sweating are really impacting my quality of life. I can't even do my hair and get dressed- let alone do my makeup- without my face and neck become drenched in sweat. I have also been experiencing insomnia and night sweats as well. It doesn't help that it's currently quite hot and humid where I live, but I have never experienced this before even when I was on my originally prescribed doses. Has anyone else experienced excessive sweating during withdrawal?


A bit more background: I was prescribed Lexapro 4½ years ago for anxiety and Body Dysmorphic Disorder, and was at one point taking 40 mg/day. I'm in a much better place than I was then and began slowly tapering off Lexapro roughly six months ago. I'm now down to 5mg/day as of a week and a half ago, and my ultimate goal is to discontinue this medication completely. I was also prescribed Abilify (5mg/day) as an adjunct about three years ago. I'm now completely off Abilify as of two weeks ago.


After doing some research, I purchased the following supplements last night to help me cope with current and future withdrawal symptoms:

  • Schisandra: I read that this berry can reduce excessive sweating and alleviate symptoms of menopause (which I may as well be going through with the constant hot flashes and night sweats) but couldn't find any anecdotes of people using it for SSRI side effects or withdrawal. I plan to take this in the evening before bed.

  • Melatonin: I plan to take this before bed to help combat withdrawal-induced insomnia.

  • Magnesium Oxide: I read that this is good for adrenal health and anxiety reduction. I plan to take this in the morning.

  • Fish Oil: I'm terrified of the dreaded "brain zaps" and I read that this can help prevent/reduce them. Omega-3s are also great for brain health and I'm hoping it will help me recover from withdrawal quicker.

  • L-Tyrosine: I'm hoping this will help my dopamine levels recover after years on Abilify, as well as combat withdrawal-related fatigue. I plan to take this in the morning.

  • Vitamin B Complex: I'm hoping this will help boost my energy. I'm also likely deficient in B12 after years as a vegetarian (yes, I know the fish oil listed above is not vegetarian but I'll take whatever helps at this point). I plan to take this in the morning.

  • 5-HTP: I used to take this back in college to help my serotonin levels recover after a night on MDMA, and I'm hoping it will do the same after years on Lexapro. I'm aware of the dangers of serotonin syndrome and don't plan to add this to my regimen until I'm completely off of Lexapro.

Thoughts on this regimen? Anything else I should add? I recently lost my health insurance coverage and am relying on my own research and the expertise of others, so any advice would be greatly appreciated :)

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  • Moderator

Hello, fleurdelice, and welcome to SA.


To start, could you please do a drug signature?  This drug history is very helpful to the moderators.  Here's how:  

Please include the dates of your taper and the rate at which you tapered.
We don't recommend a lot of supplements because our nervous systems in withdrawal are so sensitized.  Two on your list we do recommend are omega fish oil and magnesium.
Please research all supplements first and only add in one at a time and at a low dose in case you do experience problems.
While it is often a first response to stress to take a B-Complex, in withdrawal it can be overstimulating.
It's best to start Melatonin at a very low dosage, such as .25mg, and gradually increase if needed to the lowest effective dose.
At Surviving Antidepressants, it is recommended that a person taper by no more than 10% of their current dose with at least a four week hold in-between decreases.  The 10% taper recommendation is a harm reduction approach to going off psychiatric drugs.  Some people may have to taper at a more conservative rate as they are sensitive to even the smallest drops.  
Since you just finished your Abilify taper and are also suffering these withdrawal symptoms, I would consider holding where you are on the Lexapro for at least a couple of months to let your system stabilize.  At the low doses, such as 5mg, it is especially important to taper slowly.
To help you understand the symptoms you are experiencing, here is some information on withdrawal.  
Glenmullen’s withdrawal symptom list.  Sweats is one of the withdrawal symptoms listed.


When we take medications, the CNS (central nervous system) responds by making changes over the months and years we take the drug(s). When the medication is discontinued, the CNS has to undo all the changes it made. Rebuilding the neurotransmitter production and reactivating the receptor and transporter cells takes time -- during that rebuilding process symptoms occur.  

This is your introduction topic -- the place for you to ask questions, record symptoms, share your progress, and connect with other members of the SA community.  I hope you’ll find the information in the SA forums helpful for your situation.  I'm sorry that you are in the position that you need the information, but I am glad that you found us.

Gridley Introduction


Lexapro 20 mg since 2004.  Begin Brassmonkey Slide Taper Jan. 2017.   

End 2017 year 1 of taper at 9.25mg 

End 2018 year 2 of taper at 4.1mg

End 2019 year 3 of taper at 1.0mg  

Oct. 30, 2020  Jump to zero from 0.025mg.  Current dose: 0.000mg

3 year, 10 month taper is 100% complete.


Ativan 1 mg to 1.875mg 1986-2020, two CT's and reinstatements

Nov. 2020, 7-week Ativan-Valium crossover to 18.75mg Valium

Feb. 2021, begin 10%/4 week taper of 18.75mg Valium  

End 2021  year 1 of taper at 6mg

End 2022 year 2 of taper at 2.75mg 

Current dose as of Feb. 25, 2023 2mg

Taper is 89% complete.


Imipramine 75 mg daily since 1986.  Jan-Sept 2016 tapered to 14.4mg  

March 22, 2022: Begin 10%/4 week taper

Aug. 5, 2022: hold at 9.5mg and shift to Valium taper

Taper is 87% complete.  


Supplements: omega-3, vitamins C, E and D3, magnesium glycinate, probiotic, zinc, melatonin .3mg

I am not a medical professional and this is not medical advice but simply information based on my own experience, as well as other members who have survived these drugs.

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Hi Fleurdilice


I continue to experience excessive sweating during withdrawal.  It started when I first got off of my second drug Remeron.  The sweat poured off of me at night for a week.  


Now I continued to have excessive sweating, mainly at night though sometimes during the day it seems to have started back as I got to

 lower doses of my last med to taper.  I keep framing it as my body trying to heal and regulate itself. 


I get how uncomfortable it is.  I'm older than you and post menopausal but I posted a similar question about hot flashes and sweating to men on this site and got some responses that men were experiencing it to.  

9/2013-4/2014:  After moms death, was prescribed a series of meds for short periods of time that didn't work. Zoloft, Lexapro,  Nortriptyline, Liquid Prozac, Cymbalta. 

1/2014-9/2014. Clonzapam: Given Lamictal, stopped Clonzapam at .125mgs  

1/2015-4 2017 Remeron: 41.25 -0.025mgs

7/2015-11/2018 Lamictal: 200mgs-0.05 mgs Had paradoxical reaction to Lamictal wd, broke my heart to take a benzo but wasn't sleeping. 

3/28/2019 -2/5/ 2021  Clonazapam: 0.625mgs-.00115 Med Free 

July 27th, 2022**Severe Setback due to surgery/ anesthesia. 

9/7/22-10/4/22 Trazadone 50-100mgs for sleep, 10/13/22-11/13/22 Trazadone 1 mg to stabilize

10/4/22-11/20/22 Remeron 7.5mgs (for sleep doesn't work) 11/20 7.3 12/4 7.0 12/14 6.9 12/22 6.6 12/31 6.3  2023: 1/18 6.1  1/29 5.9  2/17 5.7  2/28 5.5

3/14 5.3  3/27 5.1  4/8 4.8  4/21 4.6  5/3 4.3 5/13 4.0

5/25 3.8  6/6 3.6

Additional Support:  Armour Thyroid 75mgs, Magnesium Glycinate 300-500mgs, Calms Forte, Flaxseed oil, L-theanine 

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  • ChessieCat changed the title to fleurdelice: Lexapro and Abilify withdrawal - excessive sweating

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