Jump to content

Change in drug manufacturer or generic substituted for brand-name drug


solida

Recommended Posts

  • Moderator
4 hours ago, crhawk said:

My pdoc gave me a new prescription for the 5mg Mylan, but will be harder to cut accurately. And... Pharmacy says they're running low on that one too and teva might take its place.

 

At least it will give you the ability to do a crossover.

NEW!!!              INTERVIEW with Altostrata, SA's founder               NEW!!! 

 

ADs:  25 years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after)

Pristiq:  50mg 2012, 100mg beg 2013 (Serotonin Toxicity)  Tapering Oct 2015  Current from 14 Nov 2020:  Pristiq 0.50 mg

My tapering program                                      My Intro (goes to my tapering graph)

My website - includes my brief history + links to videos & information on the web

PLEASE NOTE:  I am not a medical professional.  I provide information and make suggestions.

REMINDER TO SELF:  I don't need the drug now, but my still brain does.

Link to post
Share on other sites
  • ChessieCat changed the title to Generic vs brand - change in drug manufacturer
  • 4 weeks later...
  • Replies 88
  • Created
  • Last Reply

Top Posters In This Topic

  • Altostrata

    15

  • NewMe

    10

  • btdt

    5

  • ChessieCat

    4

Top Posters In This Topic

  • Moderator

Something to consider:

 

Do you go usually go to the same pharmacy for your drug?  If so, you could ask them to ensure that the same brand is available for you for the next refill of your script.  All they would need to do would be to put a note on one of the boxes on their shelf with your name on so that they don't sell it unless they have more of the same come in. 

 

If they are concerned that you aren't going to return for it, you could get them to hold your script, or they could always give you a phone call to check to see if you still need it.  But obviously the less work you make for them the more likely they will be to assist you.

 

And if it happened that they were not going to get the same brand in at least you would have the old brand and be able to do a cross over to a different brand.

 

CROSS OVER:

 

3/4 old + 1/4 new, 1/2 + 1/2, 1/4 old + 3/4 new  - take each of these combinations for 3 to 7 days

 

 

Edited by ChessieCat
added cross over

NEW!!!              INTERVIEW with Altostrata, SA's founder               NEW!!! 

 

ADs:  25 years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after)

Pristiq:  50mg 2012, 100mg beg 2013 (Serotonin Toxicity)  Tapering Oct 2015  Current from 14 Nov 2020:  Pristiq 0.50 mg

My tapering program                                      My Intro (goes to my tapering graph)

My website - includes my brief history + links to videos & information on the web

PLEASE NOTE:  I am not a medical professional.  I provide information and make suggestions.

REMINDER TO SELF:  I don't need the drug now, but my still brain does.

Link to post
Share on other sites
  • 2 weeks later...

Hi guys, 

 

Mentioned it in my introduction topic but perhaps more people read it here..

 

I changed citalopram manufacturer on Monday 14th Jan 2019.

 

I used to take Aurobindo but now they gave me Sandoz. It could be me but I'm having a lot of issues the last couple of days.. could this have such a big influence? 

Does any of you have experience with citalopram manufacturer swaps??

 

i have a lot of dreadful feelings of hopelessness. Normally I'm quite relaxed most evenings but now I'm pretty down until I go to bed.

 

Thanks a lot!!

 

 

Jozeff

- 2016 - Okt 2017 citalopram some months 15 mg some months 20 mg

- Nov 2017- Apr 2018 citalopram 25 mg

- April 2018 -  June 2018 citalopram 3 month TAPER too fast  from 25mg to 16.5 mg (0.1 mg per day decrease, felt horrible and crashed)

- June 2018 - Aug13th 2018 citalopram trying to stabilize at 16.5 mg for 5 weeks, felt absolutely awful.

- August 14th 2018 - April 29th 2019  citalopram 18 mg (1.5 mg updose). Try to stabilize.-

START TAPER 29 apr 2019 @ 18 mg,    29th Jun 16.4 mg / 19th aug 15.4 mg / 25th Aug 15.2 mg / 30th sep 14.0 mg / 4th dec 13.1 mg2020 citalopram taper approx 1 % per week: 03rd Jan 12.75 mg / 28 Jan 12.29 mg / 18th Feb 11.83 mg, 25th Feb 11.68 mg hold../7th May 11.33 mg hold, 4th Aug 10.98 mg. Holding because of not feeling well.

 

 

Link to post
Share on other sites
  • Moderator
32 minutes ago, jozeff said:

I changed citalopram manufacturer on Monday 14th Jan 2019.

 

I answered in your intro thread.

Gridley Introduction

 

Lexapro 20 mg since 2004.  Begin Brassmonkey Slide Taper Jan. 2017.   

End 2017 year 1 of taper at 9.25mg 

End 2018 year 2 of taper at 4.1mg

End 2019 year 3 of taper at 1.0mg  

Oct. 30, 2020  Jump to zero from 0.025mg.  Current dose: 0.000mg

3 year, 10 month taper is 100% complete.

 

Lorazepam 1 mg 1986-1991 CT, soon reinstated.  CT 2000. RI 1 mg 2011-2016.  Sept. 2016  0.625mg X 3

Nov.27, 2020 Begin 6-week Ativan-Valium crossover.

 

Imipramine 75 mg daily since 1986.  Jan. 2016 began every 3-weeks 10% taper, down to 15mg.  Aug 2016, discovered SA, updosed to 25mg and holding.  Taper is 66% complete.  

  

Supplements: omega, vitamins E and D3, magnesium glycinate, probiotic, melatonin .3mg


I am not a medical professional and this is not medical advice, but simply information based on my own experience, as well as other members who have survived these drugs.

Link to post
Share on other sites

Thank Gridley!

 

I didn't realize there was a special topic about this!

 

Cheers

 

Jozeff

- 2016 - Okt 2017 citalopram some months 15 mg some months 20 mg

- Nov 2017- Apr 2018 citalopram 25 mg

- April 2018 -  June 2018 citalopram 3 month TAPER too fast  from 25mg to 16.5 mg (0.1 mg per day decrease, felt horrible and crashed)

- June 2018 - Aug13th 2018 citalopram trying to stabilize at 16.5 mg for 5 weeks, felt absolutely awful.

- August 14th 2018 - April 29th 2019  citalopram 18 mg (1.5 mg updose). Try to stabilize.-

START TAPER 29 apr 2019 @ 18 mg,    29th Jun 16.4 mg / 19th aug 15.4 mg / 25th Aug 15.2 mg / 30th sep 14.0 mg / 4th dec 13.1 mg2020 citalopram taper approx 1 % per week: 03rd Jan 12.75 mg / 28 Jan 12.29 mg / 18th Feb 11.83 mg, 25th Feb 11.68 mg hold../7th May 11.33 mg hold, 4th Aug 10.98 mg. Holding because of not feeling well.

 

 

Link to post
Share on other sites
  • 2 months later...
Coraliefraser89

Hey everyone 2 days ago I changed brands due to pharmacy they said it’s same ingredients ect! 

Its giving me extra anxiety, I’m not sure if it’s the overthinking of it, that I’m going through withdrawal/updose so I’m not stable and I’ve had to increase sleep meds last 2 night even before the change,  so could be a number of things 

 

should I find a pharmacy with original brand of just keep on it as it’s probally from not being stable yet. 

 

Anyone had had issue with brand change and what should I do. 

50 mg Zoloft 3 years consistently 

tired to wean and have got severe side effects I cut the Zoloft 1/4 2 weeks later hit with side effects the updosed back to 50mg 

zoloft started October 2015 

25% wean February 16th 2018/ updosed 6th March due to severe side effects. 

 

Link to post
Share on other sites
  • Moderator
31 minutes ago, Coraliefraser89 said:

 

should I find a pharmacy with original brand of just keep on it as it’s probally from not being stable yet. 

 

If you can find a pharmacy with your brand, that would be best.

 

If you have any of your old brand left, it's less stressful to your system to do a crossover:

3/4 old brand, 1/4 new brand for 3 to 7 days

1/2, 1/2 for three to 7 days

1/4 old, 3/4 new for 3 to 7 days

all new thereafter

 

If you have a question that pertains to you, it's best not to start a new topic but rather to post in your Introductory thread.  That way, all your information is in one place.

Gridley Introduction

 

Lexapro 20 mg since 2004.  Begin Brassmonkey Slide Taper Jan. 2017.   

End 2017 year 1 of taper at 9.25mg 

End 2018 year 2 of taper at 4.1mg

End 2019 year 3 of taper at 1.0mg  

Oct. 30, 2020  Jump to zero from 0.025mg.  Current dose: 0.000mg

3 year, 10 month taper is 100% complete.

 

Lorazepam 1 mg 1986-1991 CT, soon reinstated.  CT 2000. RI 1 mg 2011-2016.  Sept. 2016  0.625mg X 3

Nov.27, 2020 Begin 6-week Ativan-Valium crossover.

 

Imipramine 75 mg daily since 1986.  Jan. 2016 began every 3-weeks 10% taper, down to 15mg.  Aug 2016, discovered SA, updosed to 25mg and holding.  Taper is 66% complete.  

  

Supplements: omega, vitamins E and D3, magnesium glycinate, probiotic, melatonin .3mg


I am not a medical professional and this is not medical advice, but simply information based on my own experience, as well as other members who have survived these drugs.

Link to post
Share on other sites

Yes, I had this happen with two different meds. This is pretty common. Try to find a pharmacy with your brand. I have a mail away prescription and I have my doctor write the script "XXXX brand only". I always get the right one.

 

Marie

10/13--10/14 Ambien. Started tapering 1/14  Jumped 10/14.  Done.                                                                              

3/14        7.5 Remeron  still taking this.                              

2/14         75 Trazodone   -    Tapered by dry cutting all the way down.

1/16        4 mg Trazodone  -  Jumped. Bad mistake. Got hit with late withdrawal 6 weeks later. Had to reinstate.

4/16        Reinstated 1 mg, updose to 2 mg Trazodone

2/19        .04 Trazodone. Walked off.  Done.

10/3/19  Started 7.5 Mirtazapine taper cut to .073 gram weight, pill weighs .076

4/5/20    New Mirtazapine Taper - Compound Liquid 7.35 mg April '20, 7.25 mg May, 7.05 mg June, 6.99 mg June, 6.78 mg July, 6.57 mg Aug, Sept 6.35 mg, Sept 6.24 mg, Sept 6.21 mg, Oct 5.99 mg, Oct 5.90 mg, Oct 5.70 mg.

 

Link to post
Share on other sites
  • Altostrata changed the title to Change in drug manufacturer or generic substituted for brand-name drug
  • Administrator

@Coraliefraser89 , merged similar topics, please see discussion above.

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

Link to post
Share on other sites

I think I may have a problem like this with my Seroquel.  the manufacturer changed.  I was cutting a 50 mg pill in half.  it was a pain beacause they are very hard to cut evenly.  so I asked doctor for 25 mg instead.  but the 25 has a different manufacturer.  and last two nights I am having harder time with sleep.  but, its weird im feeling better when I wake up.  go figure.  I may go back to the other original one to see what happens. 

 

but, I am also tapering another med, so it could be the sleep issue is from this as well.   

 

so hard to know sometimes. 

 9/2018- lexapro for 5 days - was low- dose rigid muscles

11/3/2018- zoloft 2 days, starting dose is.intrusive thoughts

11/7/18  - 11/15/18 - Prozac 9 days, from 10 mg for week, to 20 mg 

11/16  inpatient put on Lexapro for a few days,  Cymbalta, 2 days

11/24-12/8 - gabapentin 100 mg 3xs per day - a very fast taper

1/7 - t buspar for  three days- blurry vision, jerky eye

1/17/19 - 2/15/19- mirtazapine 15 mg - started taper on 1/30 fast

2/15/19 - inpatient .2/17-abilify, topamax given.  next day changed

2/20/19 gabapentin 600 mg, 6/5 -545 mg ,8/21  494 mg , 9/30 444mg, 11/14 399 mg, 12/10- 360 mg, 1/21-342 mg, 2/11- 324 mg (current)

2/20/19 - seroquel 25 mg 

2/20- luvox (generic) 25 mg, 4/6- 18.75 mg (current)

Link to post
Share on other sites

Hello, I posted about this on my intro post too, but I was forced to switch from Rodomel XL to Venlor XL as my GP refused to prescribe it and it’s been discontinued anyway.

 

That was around 1.5 months ago and it seems to have triggered instability, as my anxiety has been getting worse and I feel quite jittery/on edge.

 

im not sure whether I should 1) stay on venlor and pray stability returns 2) go back on Rodomel (I have enough beads for 2 months or so) and then cross taper back onto Venlor or 3) maybe try the Effexor XL brand and see if it’s more reliable?  I recall being on it before and I don't remember feeling like this on it.  It is more expensive, but if it stops me feeling like this then might be worth it.

2003-2011: Paroxetine,Citalopram,Effexor; Aug/Sept 2011: Effexor to Mirtazapine; Oct 2011: C/T Mirtazapine back to Effexor; Nov/Dec 2011: Fast Tapered Effexor - w/d hell; Feb 2012: Reinstated Effexor 37.5mg; June 2012: Dropped to 35.6mg; Jan 2016: Propranolol 2.5mg per day for general anxiety; Feb 2016: Finasteride 0.25mg per week to slow hair loss; 18th May - 8th June 2019: Started Vyvanse 7.5mg and increased by 7.5mg weekly to 30mg (lowest “therapeutic” dose for adults).; 21st June 2019 - 12th July: Cross tapered from venlafaxine brand Rodomel to Efexor (1/4 > 1/2 > 3/4 weekly before ditching Rodomel); 13th July 2019: Cut Vyvanse dose to 15mg; 15th July 2019: Akathisia returned after years of being free; 16th July 2019: Went back up to Vyvanse 30mg

Supplements: Omega-3, Vitamin D, Zinc, Phosphatidylserine 

Link to post
Share on other sites
  • 9 months later...
Healedfromabove1

MFG AMNEAL vs. MFG CAMBER(mod note: title added after merged to topic)

 

Hi everyone. I just recently got another bottle of lexapro liquid, as I have been for a while now. I’m currently at 3.75, but want to ask if this I s common or something to be concerned about...

 

my medicine tastes completely different. Could it just be because of the different brand? Will this be okay? Any insight is super appreciated, love you guys!

Edited by manymoretodays
merged to pre existing topic, title added

Klonopin starting December, 2017 -  5mg - took it for 3 maybe 4 months. 

Lexapro - 10mg starting November 2017, then perscribed 20mg two months later, am still on lexapro presently.

I cold turkeyed off of Klonopin and had horrific withdrawal, every symptom other than being hospitalized.

I cold turkeyed off of Lexapro for 5 days, reinstated back to 20 mg for 3 months before looking into tapering. (unsure how long it may have been more)

I have dropped from 20 to 3.5mg in 9.5 months. 

I just reinstated from 3.5 to 3.75mg and have been on it for 4 days.

I have taken multi vitamins, niacin, ginko baloba, amino acids, and protein drinks supplements.

I have smoked weed for 6 months, just stopped for good three weeks ago.

I have drank on the weekends in excess for many months in the past.

 

 

Link to post
Share on other sites
  • Moderator
manymoretodays

Hi Healedfromabove1, @Healedfromabove1

Hey, I merged your post here to an ongoing topic on your question, and also added it to your introduction/update page.

How are you doing since the change in manufacturers?

And if it were me, I would NOT do any further tapers, until I was sure I was doing okay on the present dose with the new manufacturer.

The change is taste is not too concerning, that just means they are using different additives for flavoring, and should not effect the actual drug that you are ingesting and ultimately absorbing.

 

That's all I've got on it, for now.  Maybe others will chime on in.

You may find something here that offers reassurance too, Healed.

Myths About Your Drugs

^ this is a nice piece that moderator brassmonkey put together, not too long ago and it may apply, @brassmonkey

 

L, P, H, and G,

mmt

Edited by manymoretodays
@'s added, link added, taste comment

Started with psycho meds circa 1988 I think 27 or 28 total.

AD's, antpsychotics, antiseizure mood stabilizers. Lithium, lamictal ,benzos, and stimulants. Some med. for narcolepsy once(Provigil,) Gabapentin........probably more.  Ask me?......I probably was on it.  Haphazard W/D's by Dr. recommend or uneducated self.

10/2014- off Lexapro--had been on highest dose 10 mg. then 5 mg. for a couple of years, went from 5 mg. to 3 mg. liquid and then CT in hospital(voluntary).  I got out of the hospital on a combination of low dose adderal salts x1/day and trileptal 150mg. x2/day.

5/28/2015-off Adderal salts 2.5mg. (I had been on that since hospital 10/2014)

12/2015---just holding, holding, holding, with trileptal/oxcarb at 75 mg. 1/2 tab at hs.  My last psycho med ever!

 

3/21/2016---I did some unwise updosing of trileptal/oxcarbazepine with some stressful stuff......doubled the above dose x2 during this last wave but began liquifying again and on approximately 68mg. starting today.  11/12//2016 24 mg. oxcarbazepine  12/9/2016 off oxcarbazepine/trileptal!!!! :) optimistic  2016 December 9- completely off all medications!!!!!

Omega3's,EPA +DHA= 1800 mg/day. Magnesium complex, orally, diluted in a liter of H2O(that I can shake up.....it usually dissolves more completely as the water gets down to room temperature) and/or Epsom salt baths prn.   Vit. C, D3, and E.  B12, melatonin tapered to 1mg., and bioidentical hormones sublingually.  Trace mineral drops.  L-lysine.  L-methylfolate=400 mcg plus daily spinach. Totally ready for a good long window to hit soon and getting better strings of full days and partial days along the way.  Definite improvement overall since I first arrived on the SA survivor ship.  Herb and alcohol free since 5/15/2016.  None of my posts are intended as medical advice.  Please discuss any decisions about your medical care with a knowledgeable medical provider. manymoretodays

 

Link to post
Share on other sites
Healedfromabove1

Thank you for this reply. I am going to be asking my doctor tomorrow to get a refill for the other brand. I am experiencing a metallic taste in my mouth and have been now for 4 days. 

Klonopin starting December, 2017 -  5mg - took it for 3 maybe 4 months. 

Lexapro - 10mg starting November 2017, then perscribed 20mg two months later, am still on lexapro presently.

I cold turkeyed off of Klonopin and had horrific withdrawal, every symptom other than being hospitalized.

I cold turkeyed off of Lexapro for 5 days, reinstated back to 20 mg for 3 months before looking into tapering. (unsure how long it may have been more)

I have dropped from 20 to 3.5mg in 9.5 months. 

I just reinstated from 3.5 to 3.75mg and have been on it for 4 days.

I have taken multi vitamins, niacin, ginko baloba, amino acids, and protein drinks supplements.

I have smoked weed for 6 months, just stopped for good three weeks ago.

I have drank on the weekends in excess for many months in the past.

 

 

Link to post
Share on other sites
1 hour ago, Healedfromabove1 said:

Thank you for this reply. I am going to be asking my doctor tomorrow to get a refill for the other brand. I am experiencing a metallic taste in my mouth and have been now for 4 days. 

You can also just go back to the pharmacy and ask them direct if they can get the old manufacturer.  

 9/2018- lexapro for 5 days - was low- dose rigid muscles

11/3/2018- zoloft 2 days, starting dose is.intrusive thoughts

11/7/18  - 11/15/18 - Prozac 9 days, from 10 mg for week, to 20 mg 

11/16  inpatient put on Lexapro for a few days,  Cymbalta, 2 days

11/24-12/8 - gabapentin 100 mg 3xs per day - a very fast taper

1/7 - t buspar for  three days- blurry vision, jerky eye

1/17/19 - 2/15/19- mirtazapine 15 mg - started taper on 1/30 fast

2/15/19 - inpatient .2/17-abilify, topamax given.  next day changed

2/20/19 gabapentin 600 mg, 6/5 -545 mg ,8/21  494 mg , 9/30 444mg, 11/14 399 mg, 12/10- 360 mg, 1/21-342 mg, 2/11- 324 mg (current)

2/20/19 - seroquel 25 mg 

2/20- luvox (generic) 25 mg, 4/6- 18.75 mg (current)

Link to post
Share on other sites
Healedfromabove1

I am going back on to the original brand. They said that CAMBER is undercutting AMNEAL by selling the drug for a third of the price. I was still able to get the AMNEAL though. I am having symptoms of withdrawal. Metallic taste, nausea, anxiety, chest pain. Crazy how a change just in brand can cause something like this. I am going to jump straight back in the dose from AMNEAL at 3.75mg and hope this symptoms go away quickly and there are no adverse reactions.

Klonopin starting December, 2017 -  5mg - took it for 3 maybe 4 months. 

Lexapro - 10mg starting November 2017, then perscribed 20mg two months later, am still on lexapro presently.

I cold turkeyed off of Klonopin and had horrific withdrawal, every symptom other than being hospitalized.

I cold turkeyed off of Lexapro for 5 days, reinstated back to 20 mg for 3 months before looking into tapering. (unsure how long it may have been more)

I have dropped from 20 to 3.5mg in 9.5 months. 

I just reinstated from 3.5 to 3.75mg and have been on it for 4 days.

I have taken multi vitamins, niacin, ginko baloba, amino acids, and protein drinks supplements.

I have smoked weed for 6 months, just stopped for good three weeks ago.

I have drank on the weekends in excess for many months in the past.

 

 

Link to post
Share on other sites
  • Moderator
ChessieCat

I found the following elsewhere and have added the following information to Post #1 of this topic.

 

On 12/17/2019 at 1:09 PM, brassmonkey said:

 

According to the FDA website:

 

"A generic medicine is the same as a brand-name medicine in dosage, safety, effectiveness, strength, stability, and quality, as well as in the way it is taken and should be used."

 

Generic medications are manufactured and inspected using the same criterion as brand name drugs and can only vary in Shape, Color, Packaging, Flavorings and Inactive ingredients.  Except for those five areas they must be exactly the same.

 

There is also a major misconception that the active ingredient is not mixed evenly through out the tablet or capsule.  Many years ago there was a case come up of a unlicensed generic manufacturer that had poor mixing quality and even some batches that didn't have any active ingredient at all.  This was a one off problem that has plagued the industry ever since.  If you buy from a reputable manufacturer you should be getting a quality product.  There are manufacturing standards that the makers have to adhere to or they face heavy fines and loss of their license.  In regards to even distribution of the active ingredient in the filler there is no problem with dry cutting tablets or taking the powder out of capsules. The same goes for commercially made liquid products.

 

 

NEW!!!              INTERVIEW with Altostrata, SA's founder               NEW!!! 

 

ADs:  25 years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after)

Pristiq:  50mg 2012, 100mg beg 2013 (Serotonin Toxicity)  Tapering Oct 2015  Current from 14 Nov 2020:  Pristiq 0.50 mg

My tapering program                                      My Intro (goes to my tapering graph)

My website - includes my brief history + links to videos & information on the web

PLEASE NOTE:  I am not a medical professional.  I provide information and make suggestions.

REMINDER TO SELF:  I don't need the drug now, but my still brain does.

Link to post
Share on other sites

×
×
  • Create New...

Important Information

Terms of Use Privacy Policy