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intothewoods: help converting Provigil / modafinil to liquid for slow taper

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intothewoods

Admin note: intothewoods was previous known under the username Out2C8383. 

 

After taking Provigil for 16 years, I've been tapering for two years and am down from 300 mg to about 12-18 mg. I say "about 12-18 mg" because the smallest tablet is 100 mg so I cut it into fourths and then attempt eighths when it starts to crumble. I've been stuck at this dose for over six months, wake every morning in frenzied CNS Provigil withdrawal (it has a short half-life, about 11 hours; I've tried taking small doses later in the day but my it makes me sicker) until I can get enough small pieces in my bloodstream to function a little. I've read that Provigil is not water-soluable but yet, I am able to liquify it easily with water.   I just don't know how to create a formula and dosing schedule but it would save my body to have a more precise amount of the drug day by day. 

Thanks to all help!!

 

 

Edited by Shep
added username to title and admin note

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Shep

Hi, Out2C8383.

 

Welcome to Surviving Antidepressants. 

 

From your post, it sounds like you may have already done some reading on this site, but just so we're on the same page, here are the links for liquid tapering: 

 

How to make a liquid from tablets or capsules

 

On 12/16/2018 at 12:39 PM, Out2C8383 said:

I've read that Provigil is not water-soluable but yet, I am able to liquify it easily with water. 

 

Please note this for drugs that have limited solubility in water:

 

On 2/27/2013 at 12:30 PM, Rhiannon said:

Mostly I would just say, I don't think it really matters if the medication is soluble in whatever vehicle you're using, as long as it can be evenly distributed. What really matters is that it be evenly distributed and that your method be repeatable and consistent.

 

As long as your being consistent, you'll be fine using water as your liquid. 

 

For more information on tapering:

 

Why taper by 10% of my dosage?

 

What is withdrawal syndrome? 

 

The Windows and Waves Pattern of Stabilization

 

Are you taking any other drugs besides Provigil? Or any supplements?

 

Please add a signature.  Include drugs, doses, dates, and discontinuations & reinstatements in the last 12-24 months. Also include supplements. This will help us give you the most accurate advice we can. 

  • Any drugs and supplements prior to 24 months ago can just be listed with start and stop years. 
  • Please use actual dates or approximate dates (mid-June, Late October) rather than relative time frames (last week, 3 months ago) 
  • Spell out months, e.g. "October" or "Oct."; 9/1/2016 can be interpreted as Jan. 9, 2016 or Sept. 1, 2016. 
  • Please leave out symptoms and diagnoses. 
  • A list is easier to understand than one or multiple paragraphs. 
  • This is a direct link to your signature:  Account Settings – Create or Edit a signature.

Once we have more information, we can better guide you in your taper.

 

Please continue to use this thread to document your symptoms and to ask plenty of questions. 

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Carmie

Hi Out2C8383, 

 

Welcome to SA, 

 

Please put in your drug signature so that we can see it at a glance every time and don’t need to go through your whole thread to find the info. Just press on the link Shep gave you. Thanks a lot. Have a read of the links Shep gave you too, especially on water titrating. You seem quite knowledgeable already. 

 

I’ve been water titrating my meds for years. I always use my 25mg tablet in 20ml of water n have used that math. I’m not great at math but somehow managed to get myself down from 300mg of Seroquel to 7.5mg. I had to start water titrating on the lower doses as I could no longer split the tablets with my tablet cutter. Some people use scales instead of water titrating, but I’ve never used them and don’t know much about them.

 

Wishing you all the best with your tapering 💚

 

 

 

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Altostrata

Welcome, out.

 

If you have a 100mg tablet, you might want to mix it in 25mL water (4mg active ingredient in 1mL), then use a 5mL oral syringe to take  4.5mL (18mg active ingredient). You'd taper by drawing up less and less in the syringe. We can help you with the calculations.

 

See Using an oral syringe and other tapering techniques

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Simmering

If you are up to it, can you say why you are tapering off Provigil?  I have recently started taking 50-100mg 2 or 3 times a week. I wish you well on your taper. Simmering 

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Carmie

Hi Out2C8383, 

 

How are doing? I see Alto gave you the math to help you with your taper. There are a number of mods that are great at math so if you need help with that just ask. You’ve done really well getting down from 300mg. Being around 12mg to 18mg doesn’t sound too accurate as you know. The water titrating will make that more accurate.

 

Please keep us updated with your taper. Thank you💚

 

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intothewoods
On 12/16/2018 at 12:39 PM, Out2C8383 said:

After taking Provigil for 16 years, I've been tapering for two years and am down from 300 mg to about 12-18 mg. I say "about 12-18 mg" because the smallest tablet is 100 mg so I cut it into fourths and then attempt eighths when it starts to crumble. I've been stuck at this dose for over six months, wake every morning in frenzied CNS Provigil withdrawal (it has a short half-life, about 11 hours; I've tried taking small doses later in the day but my it makes me sicker) until I can get enough small pieces in my bloodstream to function a little. I've read that Provigil is not water-soluable but yet, I am able to liquify it easily with water.   I just don't know how to create a formula and dosing schedule but it would save my body to have a more precise amount of the drug day by day. 

Thanks to all help!!

 

 

 

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intothewoods

Hello and Truly Sincere Thanks to all who wrote. I apologize that I'm only finding this tonight, 12/23/18, as my notifications failed. (Fixed Now :).

 

Honestly in years of embattled tapering, I've never felt such a like mind and presence nor this kind of firm hope. 

 

Tomorrow I will give proper responses but for now, to answer your question, Simmering: I was prescribed Provigil for Chronic Fatigue Syndrome 16 years ago and fully believed all the studies that it had low dependency issues. It certainly wasn't as hard on my system as Wellbutrin. But, over time and after cycling through the psychiatric system from 2012-2016 with trials of other multiple meds with Provigil - - it took hold of me. Even without all the polypharmacy, I know for me that taking anything psychotropic daily for more than a year means dependency. Never did I imagine it would exact such a hold at such a small dose at the end but I believe it's the inconsistency too. But for almost 2 years, I wake to this creeping awareness that without some little pieces of Provigil within an hour - - I'm like some junkie. I mean it's extreme and I can't stress how dangerous I know this drug to be (I have no addiction predisposition but anything that affects dopamine and makes rats crave it like cocaine... It is sobering). 

 

More tomorrow and thanks for a better night's sleep just finding this thread! ❤️

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intothewoods

Will add my drug wd signature. Somehow am unable to access it from when I joined last year but it needs updating. Progress has been made and not in small part thanks to this fantastic site 👍😊

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intothewoods

Thank you, Gridley!

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intothewoods

Again, a huge thanks to all for jumping on this so quickly and for your patience while I pull things together. Just posted wd signature. 

 

This helps to see a big event since December 15, 2018: Conversion of amitriptyline from pill to liquid with the help of my pharmacist who -- this is the wonderful part -- created a taper schedule using information from this site. Alto and Rhiannon's posts especially impressed him. (me too :) ) Using Alto's instructions, I stayed at 25 mg from pill to liquid for four days with absolutely no problems. Dropped to 22 1/2 mg Dec 11 - 13  2018, with severe withdrawal symptoms esp insomnia. Again using Alto's suggestion, I raised it to 23 1/2 mg -- closer to five percent drop rather than 10 percent -- on December 14 and am now nearly stablized.  

 

My doctor, who also loves this site and is very supportive, wants me to hold the Provigil (although it's not a steady dose, which is why I'm here now) and begin tapering the Elavil because it's causing neurological problems.

 

Re. the topic here, Provigil to liquid -- My doctor is eager for me to learn how to make a water solution (thank you for specific recipe, Alto!) so we can know exactly what I'm taking each day. As Carmie said, being so inaccurate with pill pieces is no good. I will begin water titrating ASAP with approval from you guys and to say, I am thinking to try 15 mg water tritation to start but be ready to increase or decrease until I see what my body wants. What do you think?

 

As you know, the Elavil drop December 15 is a huge player. It made me want to make the Provigil exact. I really thought I could just finally get off of the Provigil but as mentioned, never has anything held onto with such fierceness. (I will respond to Simmering a bit more below). The pharmacist is uncomfortable recommending anything with converting the Provigil. That's ok because you guys aren't and yes, I have various syringes and all other equipment needed.

 

Please do let me know of any deviation from the guidelines as I am reading and re-reading them as fast as possible. I admire the moderators and members who take such time to lend a hand, and to Alto for starting this lifesaver to begin with. 

 

 

 

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intothewoods
On 12/20/2018 at 5:50 PM, Simmering said:

If you are up to it, can you say why you are tapering off Provigil?  I have recently started taking 50-100mg 2 or 3 times a week. I wish you well on your taper. Simmering 

 

In the early years of Provigil, I took it like you, PRN or up to 3X week. I never went above 50 mg; 25 mg was usually fine. Then over time and with new doctors, I was prescribed higher doses and ultimately 200 mg tablets with daily dosing. 

 

So the big question is: Had I stayed PRN on a low dose for 14 years, would I face this horrific withdrawal? I don't know. With all of us, everything matters, everything has an impact and once so many other drugs were introduced and I destabiilized, the Provigil had me. You know the nature of it, that it's not considered an amphetamine and it's not, yet it rewires the brain over time to believe it cannot function without it. It's subtle, seductive and sadly, very little online substantiates my experience. 

 

I hope this has helped at least a little and thank you for asking. 💙

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intothewoods

Update: I made a water solution using Alto's numbers. Started with 18.5 mg this morning and slowly increased to 22.5 mg before the shakes stopped and I could walk around. (This takes between 1-2 hrs every morning)

 

Am thrilled to have an accurate measurement and know better what I've been taking. For sure, I took 25 mg and a bit higher many days during October as I was in the path of Hurricane Michael, evacuated very quickly, and was displaced for a month until my home was livable. Lots of moving around, waiting in gas lines, and .....STRESS. 

 

Thank you all for the transition to water titrating. My body and brain especially thank you. ☺️

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intothewoods
On 12/18/2018 at 10:27 PM, Carmie said:

I’ve been water titrating my meds for years. I always use my 25mg tablet in 20ml of water n have used that math. I’m not great at math but somehow managed to get myself down from 300mg of Seroquel to 7.5mg. I had to start water titrating on the lower doses as I could no longer split the tablets with my tablet cutter. Some people use scales instead of water titrating, but I’ve never used them and don’t know much about them.

 

Carmie, 

Your reduction in Seroquel is inspiring. So much work, perseverance, courage. 

 

I'm curious about your conversion formula. Do you use that as a standard for all liquid med conversions? How do you determine the active ingredient per ML? I think I am worse at math than you. 😔 

 

I see I need to make a formula that's not as concentrated or, in other words, something that allows for more leeway than 4.5 mg active ingredient to 1 ml of liquid. Maybe Alto can help too? Brain seems absent but then, the crazy Provigil reduction.😂

 

Congrats on an amazing taper journey. Like you, I have CFS. I now believe it was triggered by CNS reaction to Prozac in 1999. My family and friends and doctor agree. Hope!

 

 

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intothewoods

An afternoon update: Just when all seemed ok this morning at 22.5 mg Provigil liquid, withdrawal symptoms returned in different and fierce way. I increased twice over the next two hours to total 29 mg and finally, began to be able to function. I see from this site that it's not uncommon to have to increase dosing when you switch from hard-pill cutting to liquid because you lose a percentage in the implements plus the body reacts differently. Of course we don't know what I've actually been taking but no more than four quarter pieces of a 100 mg every four days and usually, it lasts 6-7 days. 

 

No doubt the Amitriptyline pill-to-liquid transfer and taper of Dec 15- now, combined with still recovering from hurricane for a while here, and then switching to liquid Provigil -- this is not wise. But I'll stay with the liquids because they are precise. Standardization was much needed in my drug signature. .....

 

Thanks again for the help and support, also much needed :).

 

Catherine

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Altostrata

Hello, Out2C, what are your symptoms now? Do your symptoms follow any daily pattern?  Please keep daily notes on paper about your symptoms, when you take your drugs, and their dosages. Use a simple list format with time of day on the left and notation (symptom, drug and dosage) on the right.

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intothewoods

Thanks for checking in, Altostrata. Symptoms have abated as Provigil is working its way out of system (always this time of day). That is always true in early evening but one thing, the liquid seemed easier on my system. Plus there is a huge boost in hope endorphins as I feel you are all helping eliminate the up and down dosing of Provigil particles. 

(I've been mocked by doctors and others but you know how that is 😅

 

I started a much more organized, detailed log/spreadsheet today, so I can report as accurately as possible. 

 

Also reading the backbone of the site as fast as possible so I can make your assistance easier. 

 

Thanks again. 

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ChessieCat

An example:


6 a.m. Woke with anxiety
8 a.m. Took 2.5mg Lexapro
10 a.m. Stomach is upset
10:30 a.m. Ate breakfast
11:35 a.m. Got a headache, lasted one hour
12:35 p.m. Ate lunch
4 p.m. Feel a bit better
5 p.m. Took 2.5mg Lexapro
6 p.m. Ate dinner
9:20 p.m. Headache
10:00 p.m. Took 50mg Seroquel
10:20 p.m. Feeling dizzy
10:30 p.m. Fell asleep
2:30 a.m. Woke, took 3mg Ambien (NOT "took 1/2 tablet Ambien")
2:45 a.m. Fell asleep
4:30 a.m. Woke but got back to sleep

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intothewoods

I see now.... Thanks for precise example, ChessieCat. Will do! 👍😀

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ChessieCat

Hi Out2C,

 

 

I've put the drugs you are currently taking into a drugs interaction checker and the results are pasted below.

  • Prozac
  • Provigil
  • Amitriptyline
  • Valium
  • Vistaril
  • PremPro

 

Interactions check from https://reference.medscape.com/drug-interactionchecker

Serious - Use Alternative

  • fluoxetine + amitriptyline

    fluoxetine and amitriptyline both increase serotonin levels. Avoid or Use Alternate Drug.

  • hydroxyzine + fluoxetine

    hydroxyzine increases toxicity of fluoxetine by QTc interval. Avoid or Use Alternate Drug. Increases risk of torsades de pointes.

  • fluoxetine + amitriptyline

    fluoxetine will increase the level or effect of amitriptyline by affecting hepatic enzyme CYP2C19 metabolism. Avoid or Use Alternate Drug.

Monitor Closely

  • fluoxetine + diazepam

    fluoxetine will increase the level or effect of diazepam by affecting hepatic enzyme CYP2C19 metabolism. Use Caution/Monitor.

  • modafinil + amitriptyline

    modafinil will increase the level or effect of amitriptyline by affecting hepatic enzyme CYP2C19 metabolism. Use Caution/Monitor.

  • modafinil + conjugated estrogens

    modafinil will decrease the level or effect of conjugated estrogens by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.

  • modafinil + diazepam

    modafinil will decrease the level or effect of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.

  • modafinil + medroxyprogesterone

    modafinil will decrease the level or effect of medroxyprogesterone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Contraceptirve failure possible. Use alternative if available.

  • amitriptyline + fluoxetine

    amitriptyline and fluoxetine both increase QTc interval. Modify Therapy/Monitor Closely.

  • hydroxyzine + diazepam

    hydroxyzine and diazepam both increase sedation. Use Caution/Monitor.

  • hydroxyzine + amitriptyline

    hydroxyzine and amitriptyline both increase sedation. Use Caution/Monitor.

  • hydroxyzine + modafinil

    hydroxyzine increases and modafinil decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

  • diazepam + amitriptyline

    diazepam and amitriptyline both increase sedation. Use Caution/Monitor.

  • amitriptyline + modafinil

    amitriptyline increases and modafinil decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.

Minor

  • modafinil + diazepam

    modafinil will increase the level or effect of diazepam by affecting hepatic enzyme CYP2C19 metabolism. Minor/Significance Unknown.

  • modafinil + amitriptyline

    modafinil will decrease the level or effect of amitriptyline by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown.

  • conjugated estrogens + amitriptyline

    conjugated estrogens, amitriptyline. Mechanism: unspecified interaction mechanism. Minor/Significance Unknown. Estrogens and progestins may decr tricyclic antidepressant effects, while increasing TCA plasma concentration and adverse effects.

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intothewoods

Bleck. I am aware of some of these but nothing like your list. 

Can eliminate the hydroxyzine to help straight away. Only use for insomnia emergencies but did use a lot while on the run during Hurricane Michael evac but not worth increasing fluoxetine toxicity. 

I appreciate the individualized assistance very much and have noticed you do this with others. I mean it stands out that you hone in on the meat of things. 

I feel more progress in the last 48 hrs than four years... 

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intothewoods

The fluoxetine - amitriptyline serious interaction - - I've questioned it all along and was always told because low dose of amit., that was low risk. Mayo Clinic, Johns Hopkins... They all say OK but soon will do no more harm.. 

 

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intothewoods

Awesome -- thanks. .... I am reading your website now :). 

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intothewoods

Duplication categories -- unbelievable that they just don't care.  GRRRRRRRR. 

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intothewoods

I just read something that JanCarol posted on an Introduction Forum on Friday: 

 

Each time you escape (not just reduce, but ESCAPE) by lowering dose, you are healing.
What do I mean by escape?  Well, you could quit taking quetiapine tomorrow - but that wouldn't free you of the drug, it would send you into deeper crisis.

But when you taper a small amount off, and get stable after the taper - then that is an escape.  

 

Beautiful. Reducing = Escaping

Lately I tell myself I'm on a great "sneak escape" from these insidious meds, their prescribers, and the system, and they can't stop me. They can't stop any of us. We are all on a Great Escape. 

 

Thanks, JanCarol!

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ChessieCat

This is good:

 

Video:  Healing From Antidepressants - Patterns of Recovery

 

This is another really good analogy:

 

On 8/31/2011 at 5:28 AM, Rhiannon said:

 

When we stop taking the drug, we have a brain that has designed itself so that it works in the presence of the drug; now it can't work properly without the drug because it's designed itself so that the drug is part of its chemistry and structure. It's like a plant that has grown on a trellis; you can't just yank out the trellis and expect the plant to be okay. When the drug is removed, the remodeling process has to take place in reverse. SO--it's not a matter of just getting the drug out of your system and moving on. If it were that simple, none of us would be here. It's a matter of, as I describe it, having to grow a new brain. I believe this growing-a-new-brain happens throughout the taper process if the taper is slow enough. (If it's too fast, then there's not a lot of time for actually rebalancing things, and basically the brain is just pedaling fast trying to keep us alive.) It also continues to happen, probably for longer than the symptoms actually last, throughout the time of recovery after we are completely off the drug, which is why recovery takes so long.

 

 

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intothewoods

Phenomenal video and illustration. I feel stunned, in a great way. 

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intothewoods

Checking in quickly to say I will submit my first day of notes in the morning. Wanted it to be 24 hrs. 

 

Good things since last night: Slept 10 hours, some of best sleep in years. Woke with less violent Provigil withdrawals. Dosed 29 1/2 mg immediately -- better -- but ultimately took 32 1/4 mg to function by 11 a.m.  Realized I used a different batch of Provigil generics for the liquid conversion. Could this account for discrepancy in dosing? I'm very sensitive, and becoming more so, to generic meds and can only take Modalert. Even that differs between batches. Cannot take any Provigil from any U.S. pharmacy. Started on Modalert in 2005 and didn't try to deviate until 2014 when tried several generics here and failed. 

 

Recently unable to take Fluoxetine in low-quality generics. Nausea, vomiting, dizziness. 

 

Not so good things: Crashed physically and mentally about 3 p.m. Profound distress but am working through it. Too much stimuli as I'm trying to take in as much knowledge as I can. Haven't been able to tolerate a TV since 2013. This seems more brought on by my making two liquid conversions in two weeks, and pushing myself. 

 

Wishing all a very good night, with joy and gratitude.

 

 

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intothewoods

Changed mind about daily  notes and posting in below, in case helpful. Thanks!!!!

 

Thursday, Dec. 27:

 

9 a.m.  Wake shaking in Provigil WD but not as bad as normal. Take 29 mg Provigil and 50 mg Fluoexetine.

 

10 a.m.  In bed and not fully functional. Take additional 2.5 mg Provigil to total 31.5 mg Provigil.

 

10:30  Get up, drink green smoothie. Feel can’t stay up without little more Provigil. Take 1.25 mg Provigil. Total now 32.75 mg Provigil

 

11 a.m. - Alert, confident can function. Read, housework.  

 

11:30 -- Moderate mania. Too much Provigil?

 

Noon -- Brisk walk. Feel better.

 

1 p.m. -- Provigil leveling off. Mania abates.

 

1:30 - Start draft of this schedule. Profuse sweating, anxiety. (Any serious writing causes this since drug wd; I was a journalist for most of my life; maybe deadline association?)

 

2 p.m. -- Eat main meal. (diet is mostly whole, plant-based foods)

 

3 p.m.  Afternoon crash. Provigil gone. Depressed, body and brain zaps.

 

3:30   Light exercise with music.

 

4 p.m.  Call Mom. Have meltdown. Chemistry no good. Extreme emotions from too fast a change? Not Mom’s fault.(have a fabulous Mom)

 

5 p.m.  Re-watch video ChessieCat sent: “Healing from Antidepressants -- Patterns of Recover.”  

 

5:30  Feel little better. Experience daily craving to surrender to dark bedroom for day but resist. Take shower.

 

6 p.m.  Stimuli mercilessly painful. Shakes. Stress of going on phone tieline of Bible study meeting

       In hour. Rapid heart beat. Mentally, know this is ludicrous.

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Carmie
On 12/27/2018 at 12:49 AM, Out2C8383 said:

 

Carmie, 

Your reduction in Seroquel is inspiring. So much work, perseverance, courage. 

 

I'm curious about your conversion formula. Do you use that as a standard for all liquid med conversions? How do you determine the active ingredient per ML? I think I am worse at math than you. 😔 

 

I see I need to make a formula that's not as concentrated or, in other words, something that allows for more leeway than 4.5 mg active ingredient to 1 ml of liquid. Maybe Alto can help too? Brain seems absent but then, the crazy Provigil reduction.😂

 

Congrats on an amazing taper journey. Like you, I have CFS. I now believe it was triggered by CNS reaction to Prozac in 1999. My family and friends and doctor agree. Hope!

 

 

 

Hi Out2C, 

 

I’m so sorry you have CFS as well, not much fun, is it? I’ve had it for 24 years. In the last couple of years I’ve learnt a lot about it which I didn’t know in the past. It’s a CNS illness as well. I have read lots of success stories of people taking care of their CNS and recovering. Too bad we’re going through withdrawals now as we have no chance of recovering from this illness until our CNS is no longer so compromised. On the bright side though, there is hope of recovery from CFS. 

 

Yes, I’ve always done my calculations with 20ml of water. I only started water titrating the 25mg tablet. When I was on higher doses I just used a pill cutter. 

 

My calculations were that a 25mgai tablet in 20ml of water made every ml 1.25mgai. I’ve always used a 5ml syringe. When the doses end up being teeny tiny eventually I will be using a 1ml syringe.

 

Sending hugs🤗

 

 

 

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intothewoods

Thursday, Dec. 27:

 

9 a.m.  Wake shaking in Provigil WD but not as bad as normal. Take 29 mg Provigil and 50 mg Fluoexetine.

 

10 a.m.  In bed and not fully functional. Take additional 2.5 mg Provigil to total 31.5 mg Provigil.

 

10:30  Get up, drink green smoothie. Feel can’t stay up without little more Provigil. Take 1.25 mg Provigil. Total now 32.75 mg Provigil

 

11 a.m. - Alert, confident can function. Read, housework.  

 

11:30 -- Moderate mania. Too much Provigil?

 

Noon -- Brisk walk. Feel better.

 

1 p.m. -- Provigil leveling off. Mania abates.

 

1:30 - Start draft of this schedule. Profuse sweating, anxiety. (Any serious writing causes this since drug wd; I was a journalist for most of my life; maybe deadline association?)

 

2 p.m. -- Eat main meal. (diet is mostly whole, plant-based foods)

 

3 p.m.  Afternoon crash. Provigil gone. Depressed, body and brain zaps.

 

3:30   Light exercise with music.

 

4 p.m.  Call Mom. Have meltdown. Chemistry no good. Extreme emotions from too fast a change? Not Mom’s fault.(have a fabulous Mom)

 

5 p.m.  Re-watch video ChessieCat sent: “Healing from Antidepressants -- Patterns of Recover.”  

 

5:30  Feel little better. Experience daily craving to surrender to dark bedroom for day but resist. Take shower.

 

6 p.m.  Stimuli mercilessly painful. Shakes. Stress of going on phone tieline of Bible study meeting

       In hour. Rapid heart beat. Mentally, know this is ludicrous

 

7 -  9 pm  Phone tie-in to Bible meeting. Shaking,              confused, anguish. Worse symptoms in                    over a year. Huge CFS crash in wd. 

 

9:30 - 23 2/2 mg Amitriptyline, 5 mg Valium

 

11:30 - 8:30 am   Sleep, thrashing, sweating.

 

********'****

Dec. 28, 2018

8:30 am     31 mg Provigil, 50 mg Prozac 

 

10 am  Provigil dose equalizes that wd but can't                   move from bed. 

 

2 pm -  in bed, darkest bleakness. Body like                           vibrating inside and out. This hasn't                            happened since tapered too rapidly from                  Provigil in 2017. Happened many times                     years before when didn't realize too fast                  taper. 

 

2:30 pm - Realize haven't taken  Vistaril since Dec                     24. Was trying to stop entirely since                          they are PRN. Take 25 mg Vistaril. 

 

3:30 pm - - Symptoms begin to improve. Sit up in                  bed and write this. Realize Alto needs                        info. to help 😊

                  Am thinking need to slowly back off                         Vistaril next couple of weeks. Have it in                   12.5 mg dose so can taper. 

 

To be cont. 😅  (and big thank you!!) 

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ChessieCat

Please post your notes in a block of a full day at one time.  In other words, don't post a full day plus part of a day.  It will become very confusing and make it harder for the mods to sort out.  Please also fix up the formatting for Dec 28.  It is very difficult to read.  Thanks.

 

Also what do you mean by "mania" and "chemistry no good"?  Please state the symptoms and briefly describe how you feel, not a label.  The label can easily be misinterpreted.

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intothewoods

Sorry, I totally understand and need to rework it over the weekend. Will simplify my notes. 

Thanks, ChessieCat. 

Out2C

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Altostrata
1 hour ago, Out2C8383 said:

9 a.m.  Wake shaking in Provigil WD but not as bad as normal. Take 29 mg Provigil and 50 mg Fluoexetine.

 

10 a.m.  In bed and not fully functional. Take additional 2.5 mg Provigil to total 31.5 mg Provigil.

 

What's your usual drug schedule? Provigil has a half-life of only about 15 hours. This won't maintain blood levels overnight, thus withdrawal symptoms in the morning.

 

Why are you taking Provigil with Prozac?

 

Yes, I think you took too much Provigil in the morning on Dec. 27 and had adverse reactions later in the day.

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