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BfromNJ

BfromNJ: mirtazapine taper

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BfromNJ
5 hours ago, ShiningLight said:

Hang in there. Not sure re urinary symptoms--I've certainly had some on gaba. In my opinion the rest of your log is classic gabapentin withdrawal. It's evil. There are many of us out there suffering similarly, if that helps at all. A whole battalion of us invisible and silent warriors. 

Thanks.  I am . lol.  feeling better today.  started my antibiotic so hopefully that will help the urinary issues, since there is bacteria present.  So frustrating!  now I will need to hold more on tapering till I am done with antibiotic and stable again.  Ive done just one gabapentin drop!  oh well.  better safe than sorry.  

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Boris

I started with frequent urination and genital sensations a while back while taking Pregablin/Lyrica which I believe is similar to Gabapentin? It was actually my GP that suggested it could be that medication causing the urinary issues as every test was negative (I've had cameras and tests everywhere). 

 

After reducing down from 300 to 25mg I'm now getting good windows of less needing to urinate with less intense waves. Luckily I've not had the genital sensations for quite afew months. All my cultures were negative.

 

I don't know if that helps with me being on lyrica but I thought I'd chime in with them being similar. I know how bad it can be, my life has been on hold due to this symtom. 

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BfromNJ
59 minutes ago, Boris said:

I started with frequent urination and genital sensations a while back while taking Pregablin/Lyrica which I believe is similar to Gabapentin? It was actually my GP that suggested it could be that medication causing the urinary issues as every test was negative (I've had cameras and tests everywhere). 

 

After reducing down from 300 to 25mg I'm now getting good windows of less needing to urinate with less intense waves. Luckily I've not had the genital sensations for quite afew months. All my cultures were negative.

 

I don't know if that helps with me being on lyrica but I thought I'd chime in with them being similar. I know how bad it can be, my life has been on hold due to this symtom. 

thank you Boris.  it does help to know i am not alone.  although I really hate hearing that you suffer as well.  Im glad you are doing better.   I have a ways to go, as i have just started to taper and had to hold due to needing some symptoms to settle, life changes and also this urinary issue.  I did have cultures.  one came back positive for ureaplasma bacteria, so this could be the cause of my problems or at least oontributiing to it.  its been better, thank you to god.  at least for today.  because as you very well know, it can change day to day.  But i am hopeful that it is merely the bacterial infection causing my grief and it will settle more. 

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BfromNJ
8/7 daily log
 
6:00- up
-183 mg gabapentin and probiotic
-urinary frequency 
-tinnitus and some zaps (hard to explain this, weird sensation in throat), fullness in head, feeling off- lasted the day
6:45- breakfast
-100 mg doxycycline antibiotic
9:00- legs feel activated 
- internal tremor/shaking/pulsing in left foot, leg
12- tremors worsen now also in chest, head
12:30- 183 mg gabapentin and 18.75 mg luvox
1:30- slight headache- passed
2:00- slight genital symptoms
-feeling depressed,  hopeless
-legs feel activated
6:30-doxycycline 100 mg
9:00- gabapentin 183 mg
9:30- seroquel 25 mg
- very bad nights sleep, kept waking up through the night.  pulsing, pressure sensation in head

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BfromNJ
8/8 daily log-
 
6:00- up.  sleep was terrible last night
  kept waking up, thumping sensation in head
- 183 mg gabapentin and probiotic 
6:30- weird zap sensations in head and throat when swallowing, moving head- feels like sand paper rubbing
-dizzy, feel off
8:00- tinnitus and hyperaucosis - worsens 
11:20- tinnitus worsens. and thumping/pressure in head.  
12:30- 183 mg gabapentin and 18.75 mg luvox
2:00- fatigue.  depressed, feeling hopeless, down
5:30- dinner
7:00- 100 mg doxycycline 
9:00- 183 mg gabapentin
10:00- 25 mg seroquel
 
- tinnitus and senitivity to noises along with dizzyness and feeling off and disconnected, pressure in head were the worst symptoms for today.  

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ShiningLight

By the way, be careful about the gabapentin facebook group. It used to be better than it is now. There used to be better mods and more posts from people doing slow titration. Recently there has been a culture change over there with the retirement of one of the mods. There are still people doing slow titration but they don't post as much.

 

I saw that you eat a lots of nuts and veggies. I had to be careful about eating high magnesium foods within 2 hours of gaba; I couldn't tolerate almonds at all when I was in a severe state. They would send me into a reaction. Almonds and spinach are high if I remember correctly.

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BfromNJ
1 hour ago, ShiningLight said:

By the way, be careful about the gabapentin facebook group. It used to be better than it is now. There used to be better mods and more posts from people doing slow titration. Recently there has been a culture change over there with the retirement of one of the mods. There are still people doing slow titration but they don't post as much.

 

I saw that you eat a lots of nuts and veggies. I had to be careful about eating high magnesium foods within 2 hours of gaba; I couldn't tolerate almonds at all when I was in a severe state. They would send me into a reaction. Almonds and spinach are high if I remember correctly.

you might be right on the magnesium rich foods.  as i cant tolerate magnesium supplements.  i will keep an eye on this. 

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BfromNJ

 8/9 log

 

5:45- up.  slept good
- 183 mg gabapentin and probiotic
7:00- 100 mg doxycycline
- no/low tinnitus
8:00- genital symptoms- pass by noon
- internal tremor/pulsing/shaking  in foot , groin
9:30- head feels think, thumping sensation (I think may be antibiotic)
12- lunch
-weird throat/head sensation (zaps?)
12:30- 183 mg gabapentin and 18.75 mg luvox
1:00- tinnitus starts (none all morning)

- log not finished for day.  but most of day was good symptom wise.   tinnitus was acting up but not all day.  overall felt good today. 

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ShiningLight

👏 so glad you felt better today!!!

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BfromNJ

8/12 Daily log -

 

6- up.  slept good. 
- 183 mg gabapentin and probiotic
6:30- breakfast
- 100 mg doxycycline
-urinary frequency/urgency all morning (two prior days this was much better to non existent)
12:30 - lunch
- 183 mg gabapentin and 18.75 mg luvox
- weird throat head sensation (zaps?) - starts right after eating
- pressure in head.  slight tinnitus
2:30- urinary problems lesson some, but not much
- feeling a bit down, depressed
4:00- workout
5:30- internal tremor/pulsing/vibrating in left foot, leg, genitals and abdomen
6:00- dinner
- 100 mg doxycycline
8:30- 183 mg gabapentin
9:45 - 25 mg seroquel

-urinary frequency and urgency is very bad and persisted all day.  

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eymen23

BfromNJ,

 

Until you have a follow up test to check whether the Ureaplasma bacteria is eradicated we can’t know for sure, but it’s starting to look like the urinary and genital issues are withdrawal symptoms or adverse reactions, appearing in the windows and waves format we often talk about. 

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BfromNJ
2 hours ago, eymen23 said:

BfromNJ,

 

Until you have a follow up test to check whether the Ureaplasma bacteria is eradicated we can’t know for sure, but it’s starting to look like the urinary and genital issues are withdrawal symptoms or adverse reactions, appearing in the windows and waves format we often talk about. 

I was afraid of that.  I'm still on the antibiotic till friday, but I thought I'd be better by now. This is pretty debilitating if it is and by far the worst symptom yet.  I am uncomfortable all day long and in pain.  I dont know how to ride this one out if it is adverse/withdraw related.    It is really impacting my life, making me depressed  and anxious.  I'm tired of it all.   I haven't made a cut since 6/5 .  So disheartening.  I was planning on one next week once I've made my move to VA and the antibiotic is done.  

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eymen23
27 minutes ago, BfromNJ said:

This is pretty debilitating if it is and by far the worst symptom yet.  I am uncomfortable all day long and in pain.  I dont know how to ride this one out if it is adverse/withdraw related.    It is really impacting my life, making me depressed  and anxious.  I'm tired of it all.   

 

BfromNJ,

 

I’m sorry you are in this situation and are struggling so much, but please be mindful of your tendency to catastrophize. You have experienced some windows as of late and you are likely to experience more.

 

It was only Sunday you reported reduced symptoms and an overall good day, so please try to see the positive side of things. I know that is hard in withdrawal, but we have many members who have worked on this and found ways to accept symptoms. 

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BfromNJ
28 minutes ago, eymen23 said:

 

BfromNJ,

 

I’m sorry you are in this situation and are struggling so much, but please be mindful of your tendency to catastrophize. You have experienced some windows as of late and you are likely to experience more.

 

It was only Sunday you reported reduced symptoms and an overall good day, so please try to see the positive side of things. I know that is hard in withdrawal, but we have many members who have worked on this and found ways to accept symptoms. 

sorry if I sound as though I am catastrosizing.  I do not mean to.  I seems everytime I have a window, the next wave is even worse.    Its hard to do anything when you are in the bathroom literally all day long.  :(     What I am thinking about is this - I do not see in my research that frequent urination/urgency is a side effect of the gabapentin.  But it is listed pretty high up in the side effects of the luvox.  So this is just making me rethink my next course of action as far as tapering.    I reduced luvox already back in april, a big cut of 25%.  But then it looked like I was having adverse reaction from gabapentin so it was suggested I go for the gabapentin reduction and hold off on the luvox.  I have done one one gabapentin reduction on 6/5 of 8%.   And that is where I have remained, due to the antibiotics, etc.   I suppose I stay the course still with the gabapentin, even if it isn't the cause of my urinary woes, as I guess I cant know for sure. 

 

Of course, this could still be infection related.  Never thought I would be hopeful for an infection.  sigh.....

 

I am going to see if I can find on here and online any ways to reduce the urinary discomfort naturally, if that is even possible.  Besides dehydrating myself.  lol. 

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BfromNJ

@brassmonkey

@ChessieCat

 

or whomever else reads this.  

 

Hello. I have a question   Not on tapering seroquel but here goes.   I did know where to post this.   I take 25 mg.  I was cutting a 50 mg pill in half.  Some time ago my doctor did give me 25 mg to make things easier, but i took it one night and did not sleep well, so i thought it was that maybe active ingredient differnece or something.  So i went back to just taking half a 50.  I have a hard time cutting them, so i recently tried to take the 25 mg tablet again and actually did fine with it.  seemed to sleep even better.  Turns out its the same manufacturer.  

 

Im just wondering if this could give me problems ?  Is it considered making a change?  Im not sure how it works filler wise and active ingredient. Like if i was even getting an even amount of active ingredient by cutting or if the filler amounts/type vary from one dosage strength to another.   I did measure both pieces on my scale afterward just to be sure, and if the were off i would make sure to even it out with another extra little piece or take off it it was over.    I would think this is even better to just take the 25 mg since its consistant?  

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manymoretodays
Posted (edited)

Hi BfromNJ,

Are you on the immediate release form of Seroquel?

Extended release is labeled XR.

 

Tips for tapering off Seroquel(quetiapine)

Splitting an extended-release tablet appears possible (there are many reports on the Web of people doing this), but this compromises the extended-release quality, possibly resulting in immediate-release quetiapine. If you are used to the extended-release form, you may be sensitive to the "dosage dumping" resulting from immediate release of the drug.

(not to worry about this ^, if you have been using immediate release all along)

 

If you were halving the immediate release AND weighing you were okay.......I do see your point though, of the ease of a 25 mg tablet.

 

If you are on the immediate release and your new tablet is immediate release, same manufacturer, I don't you need to worry on active ingredient and filler changes at all. 

There might be a minimal adjustment, to deal with, yet, maybe none.

You may be good to go with the 25 mg tablet.  We usually encourage some form of crossover from old to new:

3/4 old + 1/4 new, hold for 3-7 days

1/2 old + 1/2 new, same hold

1/4 old + 3/4 new, same hold

Then on to the dose with your new tablet.

 

You've had some windows!  Yay!  And when is the upcoming move?

L, P, H, and G,

mmt

 

 

 

Edited by manymoretodays

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BfromNJ
Posted (edited)

No its not extended release.   The move is Saturday.  Yikes!

 

Edited by ChessieCat
removed quote

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manymoretodays
Posted (edited)

That's good then.

If you have some of the old, you could do 1/4 of that(12.5 mg) and half of the new 25 mg(12.5 mg) for a couple of nights. 

And then just go to the new.

 

Practice your coping skills, as much as you can, self soothe, etc.  Moving is a biggie. 

I think you are going to be fine with it, BfromNJ.  From what you've said.......it's for the better.  More community and family to be around will be great! 

People need other people.  If your bio family works for you......that's a plus.

I'm optimistic.  Yes, Yikes.  Plenty to keep you busy I'm sure.

 

L, P, H, and G,

mmt

Edited by manymoretodays

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BfromNJ

This may seem like a dumb question, but here goes.  Can you get withdrawal after finishing a round of antibiotics?   

10 hours ago, manymoretodays said:

That's good then.

If you have some of the old, you could do 1/4 of that(12.5 mg) and half of the new 25 mg(12.5 mg) for a couple of nights. 

And then just go to the new.

 

Practice your coping skills, as much as you can, self soothe, etc.  Moving is a biggie. 

I think you are going to be fine with it, BfromNJ.  From what you've said.......it's for the better.  More community and family to be around will be great! 

People need other people.  If your bio family works for you......that's a plus.

I'm optimistic.  Yes, Yikes.  Plenty to keep you busy I'm sure.

 

L, P, H, and G,

mmt

I could try that.  I didnt think to do a crossover.  Its just that its such a pain to cut the 50 mg, probably even harder to quarter them.  I have just been taking the new 25s.     So you think that the new 25s (same manufacturer) has the same strength as cutting the 50s in half?   Just want to make sure i dont upset the apple cart.  lol.   im sure i will adjust.  i do feel more clear headed the next morning and day, not so dopey.  which is a plus.  But, it seems like my urinary issues is worse the last couple of days.  Yesterday, it was terrible in the am, then by late afternoon it was like i had no problems at all.  I was then thinking, hmm, maybe its the seroquel thats doing it and the new 25s are making it worse. but i would think if its pretty much the same dose wise, etc that could not be it.   

So this may be a dumb question, but here goes.  lol 

 

Is it possible to have withdrawal symptoms after finishing an antibiotic?   

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manymoretodays
2 hours ago, BfromNJ said:

 

Is it possible to have withdrawal symptoms after finishing an antibiotic?   

 

Hi BfromNJ,

My best guess is, that it's not so much ABX WD, rather just another change to your whole system, and the subsequent CNS/ANS response to that.  A little change in the "apple cart" is all.

Here's what we've got collected, as far as ABX go, cautions, and other members experiences.

Cipro, Levaquin, Azithromycin(Z-pack)and other antibiotic

 

3 hours ago, BfromNJ said:

I have just been taking the new 25s.     So you think that the new 25s (same manufacturer) has the same strength as cutting the 50s in half? 

 

With your new 25 mg Seroquel, same manufacturer, yes, I do think the active ingredient is going to be 25 mg.  Of course, you might be feeling a bit of adjustment variance.  If you have already gone 7 days with the new.......if I were you, I'd just ride it out.  Otherwise, go ahead with some form of crossover(as described above).  That should limit any waveish-ness I think.

 

L, P, H, and G,

mmt

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BfromNJ

I've been very busy with the move and settling in.  So not here much.  I've holding my own I guess.  Urinary issues are still quite an annoyance and disruption to my day..  and painful.   I am stuck until I have my new insurance if I want to follow up with doctor.  

 

I have an interview today.  Which is great.   Fingers crossed!  

 

I am planning a gabapentin reduction tomorrow.  It will be 7%.  Figured I'd do a bit less than the 10% but more than 5.  😁

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BfromNJ

So I actually decided on 10% for this reduction.  First dose this morning.  I will log it .

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BfromNJ

Well this will be my 4th day of my gabapentin drop.  I am guilty of not doing my daily logs I must admit.  I have been settling in with my move and out of the routine of doing them.  I know they are important but sometimes I feel as though in doing them I focus on my symptoms , etc too much and become ocd about it.  I feel like then it just brings them too much front and center.  Any one have advice on this?  

 

 The only thing this far I have noticed is starting last night an increase in my tinnitus.  I still struggle with urinary and genital issues.  Most distressing is the discomfort of urinary urgency and frequency.  It's pretty constant now and oh so uncomfortable.  And pain in the area. I've also been very bloated and feel a constant pressure.  I cant go to doctor yet as my new insurance does not start until 9/1.  I feel like this may not be drug or withdraw related but we shall see. 

 

 

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ShiningLight

Glad to hear your drop is going well! You could also think of the log as a way to keep your focus off the symptoms, by writing it down and getting it out of your head.

 

Good for you for going on an interview in the middle of all this!!! How did it go?

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